Genomes and Genes
Summary: General term for a group of MALNUTRITION syndromes caused by failure of normal INTESTINAL ABSORPTION of nutrients.
Publications195 found, 100 shown here
- Chylomicron retention disease--the role of ultrastructural examination in differential diagnosisR Boldrini
Dipartimento di Anatomia Patologia, , IRCCS, Roma, Italy
Pathol Res Pract 197:753-7. 2001..together with clinical aspects and laboratory measurements. In this study, we describe the histological and ultrastructural aspects observed in three pediatric cases of CRD...
- The role of the microsomal triglygeride transfer protein in abetalipoproteinemiaN Berriot-Varoqueaux
U327 Institut National de la Santé et de la Recherche Médicale, Faculte de Medecine Xavier Bichat, Université de Paris 7 Denis Diderot, 75870 Paris, France
Annu Rev Nutr 20:663-97. 2000..Unless treated, abetalipoproteinemic subjects develop gastrointestinal, neurological, ophthalmological, and hematological abnormalities...
- Review article: fructose malabsorption and the bigger pictureP R Gibson
Department of Gastroenterology and Monash University Department of Medicine, Box Hill Hospital, Victoria, Australia
Aliment Pharmacol Ther 25:349-63. 2007....
- Fructose malabsorption and symptoms of irritable bowel syndrome: guidelines for effective dietary managementSusan J Shepherd
Department of Gastroenterology and Monash University, Victoria, Australia
J Am Diet Assoc 106:1631-9. 2006..01), as was improvement in individual symptoms (P<0.01 for all symptoms). This comprehensive fructose malabsorption dietary therapy achieves a high level of sustained adherence and good symptomatic response...
- Imerslund-Gräsbeck syndrome (selective vitamin B(12) malabsorption with proteinuria)Ralph Gräsbeck
Biochemistry Unit, Minerva Foundation Institute for Medical Research, Biomedicum Helsinki, FI 00290 Helsinki, Finland
Orphanet J Rare Dis 1:17. 2006..In diagnosing this disease, it is important to be aware that cobalamin deficiency affects enterocyte function; therefore, all tests suggesting general and cobalamin malabsorption should be repeated after abolishment of the deficiency...
- Medical follow up after bariatric surgery: nutritional and drug issues. General recommendations for the prevention and treatment of nutritional deficienciesO Ziegler
Unité Multidisciplinaire de Chirurgie de l Obésité, CHU de Nancy
Diabetes Metab 35:544-57. 2009....
- Fructose malabsorption is associated with decreased plasma tryptophanM Ledochowski
Dept of Clinical Nutrition, Institute for Medical Chemistry and Biochemistry, University of Innsbruck, Austria
Scand J Gastroenterol 36:367-71. 2001..Recently it was found that fructose malabsorption was associated with early signs of depressive disorders. Therefore, it was investigated whether fructose malabsorption is associated with abnormal tryptophan metabolism...
- Ancient founder mutation is responsible for Imerslund-Gräsbeck Syndrome among diverse ethnicitiesCameron M Beech
Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA
Orphanet J Rare Dis 6:74. 2011..We present evidence that this founder mutation causes a substantial percentage of cases among diverse ethnicities and that the mutation is as old as human civilization...
- Juvenile selective vitamin B₁₂ malabsorption: 50 years after its description-10 years of genetic testingRalph Gräsbeck
Minerva Foundation Institute for Medical Research, Biomedicum Helsinki 2U, Helsinki 00290, Finland
Pediatr Res 70:222-8. 2011..Clinical awareness must include attention to ethnicity, a sensitive topic but effective for fast diagnosis. The treatment with monthly parenteral Cbl for life offers a simple and cost-effective solution once proper diagnosis is made...
- Iron deficiency and anaemia in bariatric surgical patients: causes, diagnosis and proper managementM Munoz
School of Medicine, University of Malaga, Malaga, Spain
Nutr Hosp 24:640-54. 2009..New IV preparations, such ferric carboxymaltose, are safe, easy to use and up to 1000 mg can be given in a single session, thus providing an excellent tool to avoid or treat iron deficiency in this patient population...
- [Nutritional deficiencies associated with bariatric surgery]Vanessa Folope
Unité de Nutrition et groupe ADEN EA3234, IFR23, CHU de Rouen, Rouen, France
Gastroenterol Clin Biol 31:369-77. 2007..The case by case correction of these deficiencies is mandatory, and their systematic prevention should be evaluated...
- Luminal expression of cubilin is impaired in Imerslund-Grasbeck syndrome with compound AMN mutations in intron 3 and exon 7Fares Namour
Faculte de Medecine, INSERM U954 Nutrition, Genetics, and Environmental Risk Exposure, Vandoeuvre les Nancy, France
Haematologica 96:1715-9. 2011..Heterozygous carriers for c.742T and c.208-2G had no pathological signs. These results indicate that amnionless is essential for the correct luminal expression of cubilin in humans...
- Identification of an intestinal folate transporter and the molecular basis for hereditary folate malabsorptionAndong Qiu
Department of Medicine, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
Cell 127:917-28. 2006..However, the current study establishes that a major function of this gene product is proton-coupled folate transport required for folate homeostasis in man, and we have thus amended the name to PCFT/HCP1...
- Anemia after bariatric surgery: more than just iron deficiencyAnnette Von Drygalski
VA San Diego Healthcare System, La Jolla Medical Center, 3350 La Jolla Village Dr, 111E, San Diego, CA 92161, USA
Nutr Clin Pract 24:217-26. 2009....
- Obesity, bariatric surgery, and iron deficiency: true, true, true and relatedAileen L Love
Department of Medicine, Weill Cornell Medical Center, New York, New York, USA
Am J Hematol 83:403-9. 2008..Bariatric surgery patients require lifelong follow-up of hematological and iron parameters since iron deficiency and anemia may develop years after surgery...
- Benefits of breath hydrogen testing after lactulose administration in analysing carbohydrate malabsorptionJohn P Bate
Departments of Medicine and Gastroenterology, Monash University, Box Hill Hospital, Box Hill, Victoria, Australia
Eur J Gastroenterol Hepatol 22:318-26. 2010..We examined the contribution of breath testing after lactulose administration to the conduct and interpretation of breath hydrogen responses after fructose and lactose administration...
- Current spectrum of malabsorption syndrome in adults in IndiaPooja Yadav
Department of Microbiology, All India Institute of Medical Sciences, New Delhi, India
Indian J Gastroenterol 30:22-8. 2011..Tropical sprue was considered to be the most important cause of malabsorption in adults in India. However, several reports indicate that celiac disease is now recognized more frequently...
- Ability of the normal human small intestine to absorb fructose: evaluation by breath testingSatish S C Rao
Department of Internal Medicine and Clinical Research Center, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242 1009, USA
Clin Gastroenterol Hepatol 5:959-63. 2007..We performed a dose-response study of fructose absorption in healthy subjects to develop a breath test to distinguish normal from abnormal fructose absorption capacity...
- A randomized, double-blind, placebo-controlled trial of rifaximin, a nonabsorbable antibiotic, in the treatment of tropical enteropathyIndi Trehan
Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri, USA
Am J Gastroenterol 104:2326-33. 2009..This study tested the hypothesis that treatment with a nonabsorbable, broad-spectrum antibiotic, rifaximin, reduces the L:M ratio in rural Malawian children, among whom tropical enteropathy is common...
- Sugar malabsorption in functional abdominal bloating: a pilot study on the long-term effect of dietary treatmentFernando Fernández-Bañares
Department of Gastroenterology, Hospital Universitari Mutua Terrassa, Plaza Dr Robert 5, 08221 Terrassa, Barcelona, Spain
Clin Nutr 25:824-31. 2006..Gas-related complaints (i.e., passage of flatus), which are present in a subgroup of these patients, might be associated with carbohydrate malabsorption...
- Low rate of production of apolipoproteins B100 and AI in 2 patients with Anderson disease (chylomicron retention disease)Khadija Ouguerram
INSERM UMR 1087 CNRS UMR 6291 and CRNH Nantes, IRT UN, Nantes, France
Arterioscler Thromb Vasc Biol 32:1520-5. 2012..The aim of this article was to analyze the mechanisms responsible for the low plasma apolipoprotein Apo-B100 and Apo-AI in 2 patients with Anderson disease...
- Inherited cobalamin malabsorption. Mutations in three genes reveal functional and ethnic patternsStephan M Tanner
Human Cancer Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, OH 43210, USA
Orphanet J Rare Dis 7:56. 2012..IGS and IFD differ in that IGS usually presents with proteinuria, which is not observed in IFD. The genetic heterogeneity and numerous differential diagnoses make clinical assessment difficult...
- Etiological spectrum of sporadic malabsorption syndrome in northern Indian adults at a tertiary hospitalPiyush Ranjan
Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
Indian J Gastroenterol 23:94-8. 2004..CONCLUSIONS: Tropical sprue, celiac disease and Crohn's disease are common causes of MAS in Indian adults. Inappropriate anti-tubercular treatment is common in them and needs to be discouraged...
- Molecular study of proteinuria in patients treated with B₁₂ supplements: do not forget megaloblastic anemia type 1Nomy Levin-Iaina
Nephrology and Hypertension Institute, Department of Medicine, Tel Aviv University, Sackler School of Medicine, Chaim Sheba Medical Center, Tel Hashomer, Israel
Nephron Clin Pract 118:c67-71. 2011..In the present study, we describe 2 Israeli Jewish patients with MGA1 and isolated proteinuria...
- An exon 53 frameshift mutation in CUBN abrogates cubam function and causes Imerslund-Gräsbeck syndrome in dogsJohn C Fyfe
Laboratory of Comparative Medical Genetics, College of Veterinary Medicine, Michigan State University, East Lansing, MI 48824, USA
Mol Genet Metab 109:390-6. 2013..The border collie disorder indicates that a CUBN mutation far C-terminal from the intrinsic factor-cobalamin binding site can abrogate receptor expression and cause Imerslund-Gräsbeck syndrome. ..
- Hyperammonaemic encephalopathy secondary to selective cobalamin deficiency in a juvenile Border collieI A Battersby
Department of Clinical Veterinary Science, University of Bristol, Langford, Bristol BS40 5DU
J Small Anim Pract 46:339-44. 2005....
- Imerslund-Gräsbeck syndrome in a 15-year-old German girl caused by compound heterozygous mutations in CUBNFabian H Hauck
Department of Paediatrics, University Hospital Carl Gustav Carus at the Technical University Dresden, Dresden, Germany
Eur J Pediatr 167:671-5. 2008..Diagnosis should be confirmed genetically to avoid further invasive diagnostics, administer proper lifelong treatment and offer genetic counselling...
- Nutritional markers following duodenal switch for morbid obesityRobert A Rabkin
Pacific Laparoscopy, San Francisco, CA, USA
Obes Surg 14:84-90. 2004..In LapDS, both the quantity of food ingested and the efficiency of digestion are reduced...
- A role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosisRongbao Zhao
Departments of Medicine and Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, New York 10461, USA
J Biol Chem 284:4267-74. 2009....
- Intestinal fructose transport and malabsorption in humansHilary F Jones
Mechanisms in Cell Biology and Disease Research Group, Sansom Institute for Health Research, Univ of South Australia, South Australia 5001, Australia
Am J Physiol Gastrointest Liver Physiol 300:G202-6. 2011..Understanding the relative roles of these transporters in humans will be crucial for establishing a mechanistic basis for fructose malabsorption in gastrointestinal patients...
- Spectrum and antibiotic sensitivity of bacteria contaminating the upper gut in patients with malabsorption syndrome from the tropicsUjjala Ghoshal
Department of Microbiology Sanjay Gandhi Postgraduate Institute of Medical Sciences Lucknow 226014, India
BMC Gastroenterol 3:9. 2003..Frequency, nature and antibiotic sensitivity of SIBO in patients with MAS are not well understood...
- The spectrum of mutations in the PCFT gene, coding for an intestinal folate transporter, that are the basis for hereditary folate malabsorptionRongbao Zhao
Departments of Medicine, Molecular Pharmacology, Albert Einstein College of Medicine, Bronx, NY 10461, USA
Blood 110:1147-52. 2007....
- The mechanism of the formation and secretion of chylomicronsTammy Kindel
University of Cincinnati College of Medicine, United States
Atheroscler Suppl 11:11-6. 2010..The physiologic role of apo B-48 in the intestine is presented as well as clinical disease of chylomicron metabolism, specifically abetalipoproteinemia and Anderson's disease...
- The clinical course and genetic defect in the PCFT gene in a 27-year-old woman with hereditary folate malabsorptionSang Hee Min
Department of Medicine, Albert Einstein College of Medicine, Bronx, NY, USA
J Pediatr 153:435-7. 2008....
- Inborn errors of cobalamin absorption and metabolismDavid Watkins
Department of Human Genetics, McGill University, Canada
Am J Med Genet C Semin Med Genet 157:33-44. 2011..Two other disorders, haptocorrin deficiency and transcobalamin receptor deficiency, have been described, but it is not clear that they have any consistent clinical phenotype...
- Decreased expression of Intestinal I- and L-FABP levels in rare human genetic lipid malabsorption syndromesS Guilmeau
Institut National de la Sante et de la Recherche Medicale INSERM, U773, Centre de Recherche Bichat Beaujon CRB3, Universite Paris 7 Denis Diderot, site Bichat, BP 416, 75018, Paris, France
Histochem Cell Biol 128:115-23. 2007We investigated, for the first time, the expression of I- and L-FABP in two very rare hereditary lipid malabsorption syndromes as compared with normal subjects...
- A novel loss-of-function mutation in the proton-coupled folate transporter from a patient with hereditary folate malabsorption reveals that Arg 113 is crucial for functionInbal Lasry
The Fred Wyszkowski Cancer Research Laboratory, Department of Biology, Technion Israel Institute of Technology, Haifa, Israel
Blood 112:2055-61. 2008..These findings establish a novel loss of function mutation in HFM residing in an intracellular loop of PCFT crucial for folate transport...
- Coincidental malabsorption of lactose, fructose, and sorbitol ingested at low doses is not common in normal adultsS D Ladas
Second Department of Internal Medicine, Athens University, Evangelismos Hospital, Greece
Dig Dis Sci 45:2357-62. 2000..In conclusion, the frequency of coincidental malabsorption of lactose, fructose, and sorbitol and intolerance to these sugars is not common, when normal adults ingest them at low doses...
- Fecal energy losses in enterally fed intensive care patients: an explorative study using bomb calorimetryR J M Strack van Schijndel
Department of Intensive Care, VU University Medical Center, PO Box 7057, 1007 MB Amsterdam, The Netherlands
Clin Nutr 25:758-64. 2006..The purpose of this explorative study was to evaluate the energy losses of patients with loose stools, necessitating the use of a feces-collector device in a tertiary academic ICU...
- Fructose malabsorption: true condition or a variance from normalityMoe Htet Kyaw
Digestive Diseases Centre, Leiceter Royal Infirmary Square, Leicester, UK
J Clin Gastroenterol 45:16-21. 2011..This low level may be difficult to exclude from the daily diet, resulting in symptoms of fructose malabsorption...
- Carbohydrate intolerance in patients with self-reported food hypersensitivity: comparison of lactulose and glucoseJørgen Valeur
Institute of Medicine, University of Bergen, Bergen, Norway
Scand J Gastroenterol 44:1416-23. 2009..We investigated symptom anticipation and microbial fermentation as possible mechanisms of carbohydrate intolerance in patients with self-reported food hypersensitivity...
- Dietary fructose intolerance: diet modification can impact self-rated health and symptom controlFrederick C Johlin
Division of Gastroenterology, Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
Nutr Clin Care 7:92-7. 2004..DFI can cause significant gastrointestinal symptoms that may not respond to medications or surgical interventions. Symptoms can improve and self-rated health does improve in DFI patients willing to adhere to a low fructose diet...
- Predictors of weight loss and reversal of comorbidities in malabsorptive bariatric surgeryMaria E Valera-Mora
Department of Internal Medicine, Catholic University of Rome, Rome, Italy
Am J Clin Nutr 81:1292-7. 2005..Cardiovascular and metabolic comorbidities are dramatically increased in severe obesity, a condition highly resistant to nonsurgical therapy...
- Treatment of vitamin D deficiency with UV light in patients with malabsorption syndromes: a case seriesPrakash Chandra
Graduate Program in Nutrition and Health Sciences and Department of Medicine, Emory University School of Medicine, Atlanta, GA 30307, USA
Photodermatol Photoimmunol Photomed 23:179-85. 2007..We evaluated whether a commercial portable ultraviolet (UV) indoor tanning lamp that has a spectral output that mimics natural sunlight could raise circulating 25-hydroxyvitamin D [25(OH)D] levels in subjects with CF and SBS...
- Anderson's disease (chylomicron retention disease): a new mutation in the SARA2 gene associated with muscular and cardiac abnormalitiesM Silvain
CNRS, Centre de Genetique Moleculaire, UPR2167, Gif sur Yvette, France
Clin Genet 74:546-52. 2008..These results suggest that myolysis and other extraintestinal abnormalities can occur in AD/CMRD and that the clinical evaluation of patients should reflect this...
- Homozygous AMN mutation in hereditary selective intestinal malabsorption of vitamin B12 in JordanJamil R Al-Alami
Department of Biochemistry and Medical Laboratory Science, Jordan University of Science and Technology, Irbid, Jordan
Saudi Med J 26:1061-4. 2005..Several syndromes present with megaloblastic anemia such as congenital megaloblastic anemia due to intrinsic factor defect and juvenile megaloblastic anemia with proteinuria due to defects in the cubilin or the amnionless protein...
- Fructose intake at current levels in the United States may cause gastrointestinal distress in normal adultsPeter L Beyer
Department of Dietetics and Nutrition, University of Kansas Medical Center, Kansas City 66160, USA
J Am Diet Assoc 105:1559-66. 2005..The purpose was to determine how often fructose, in amounts commonly consumed, would result in malabsorption and/or symptoms in healthy persons...
- Usefulness of jejunal biopsy in the study of intestinal malabsorption in the elderlyB Lobo
Service of Digestive Diseases, University Hospital Vall d Hebron, Barcelona, Spain
Rev Esp Enferm Dig 96:259-64. 2004..A key test for the etiologic diagnosis of intestinal malabsorption, jejunal biopsy, has not been specifically examined to assess its usefulness and risk of complications in this advanced age patients...
- Nutritional and metabolic complications of bariatric surgeryScott S Malinowski
Department of Pharmacy Services, Division of Digestive Health and Nutrition, University of Mississippi Medical Center, Jackson, Mississippi 39216 4505, USA
Am J Med Sci 331:219-25. 2006..Counseling, monitoring, and nutrient and mineral supplementation are essential for the treatment and prevention of nutritional and metabolic complications after bariatric surgery...
- Variable phenotypic expression of chylomicron retention disease in a kindred carrying a mutation of the Sara2 geneAngelo B Cefalù
Departmet of Clinical Medicine and Emerging Diseases, University of Palermo, I 90127 Palermo, Italy
Metabolism 59:463-7. 2010..More studies are needed to understand the reasons of the phenotypic variability of the same molecular defect in the same family...
- Utility of hydrogen breath tests in diagnosis of small intestinal bacterial overgrowth in malabsorption syndrome and its relationship with oro-cecal transit timeUday C Ghoshal
Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow
Indian J Gastroenterol 25:6-10. 2006..Quantitative culture of upper gut aspirate is used as a gold standard for the diagnosis of SIBO. Studies on diagnosis of SIBO using non-invasive hydrogen breath tests are contradictory...
- Molecular analysis and intestinal expression of SAR1 genes and proteins in Anderson's disease (Chylomicron retention disease)Amandine Georges
INSERM U781, Universite Paris Descartes, Hopital Necker Enfants Malades, Paris, 75015, France
Orphanet J Rare Dis 6:1. 2011....
- Nonradioactive vitamin B12 absorption test evaluated in controls and in patients with inherited malabsorption of vitamin B12Mustafa Vakur Bor
Department of Clinical Biochemistry, NBG, As, Aalborg Hospital, Aarhus University Hospital, Denmark
Clin Chem 51:2151-5. 2005..Current tests for evaluation of vitamin B(12) absorption are problematic because they involve the use of radioactively labeled vitamin B(12). We describe a vitamin B(12) absorption test that circumvents this problem...
- Guidelines for the diagnosis and management of chylomicron retention disease based on a review of the literature and the experience of two centersNoel Peretti
Department of Nutrition, CHU Sainte Justine Research Center, Universite de Montreal, 3175, Ste Catherine Road, Montreal, Quebec, H3T 1C5, Canada
Orphanet J Rare Dis 5:24. 2010..The clinical guidelines proposed will helpfully lead to an earlier diagnosis and the prevention of complications...
- Bioavailability of a novel, water-soluble vitamin E formulation in malabsorbing patientsKonstantinos Papas
Yasoo Health Inc, Johnson City, TN 37604, USA
Dig Dis Sci 52:347-52. 2007..09). In conclusion, this novel, water-soluble formulation showed a marked and statistically significant increase in absorption of gamma-tocopherol in malabsorbing patients with CF compared with an oil-based formulation...
- Mutations in a Sar1 GTPase of COPII vesicles are associated with lipid absorption disordersBethan Jones
Genomic and Molecular Medicine Group, MRC Clinical Sciences Centre, Imperial College, London, England, UK
Nat Genet 34:29-31. 2003..Our data suggest that chylomicrons, which vastly exceed the size of typical COPII vesicles, are selectively recruited by the COPII machinery for transport through the secretory pathways of the cell...
- Late onset of Imerslund-Gräsbeck syndrome without proteinuria in four children of one family from the LebanonJochen Rossler
Department of Paediatric Haematology Oncology and Endocrinology, Children s Hospital, University of Essen, 45122 Essen, Germany
Eur J Pediatr 162:808-9. 2003
- Spectrum of malabsorption in India--tropical sprue is still the leaderA K Dutta
Department of Gastrointestinal Sciences, Christian Medical College and Hospital, Vellore 632 004
J Assoc Physicians India 59:420-2. 2011..The aim of this study therefore was to assess the spectrum of malabsorption seen at our center during the past nine years...
- Vitamin B 12 malabsorption due to a biologically inert intrinsic factorM Katz
N Engl J Med 287:425-9. 1972
- Effect of nonabsorbed amounts of a fructose-sorbitol mixture on small intestinal transit in healthy volunteersJan L Madsen
Department of Clinical Physiology and Nuclear Medicine, Hvidovre Hospital, University Hospital of Copenhagen, Copenhagen, Denmark jan lysgaard madsen hh hosp dk
Dig Dis Sci 51:147-53. 2006..0128). In healthy humans, malabsorption of small amounts of a fructose-sorbitol mixture accelerates small bowel transit...
- Carbohydrate malabsorption and the effect of dietary restriction on symptoms of irritable bowel syndrome and functional bowel complaintsR Goldstein
Gastroenterology Institute, Shaare Zedek Medical Center, Jerusalem, Israel
Isr Med Assoc J 2:583-7. 2000..Elimination of the offending sugar(s) should result in clinical improvement...
- Hereditary folate malabsorption: family report and review of the literatureJames Geller
Department of Pediatrics, New York Medical College, Valhalla, New York 10595, USA
Medicine (Baltimore) 81:51-68. 2002
- 1H NMR spectroscopic method for diagnosis of malabsorption syndrome: a pilot studyLakshmi Bala
Centre of Biomedical Magnetic Resonance, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Raebareli Road, Lucknow 226 014, India
NMR Biomed 17:69-75. 2004..The NMR method is simple and may be more accurate for the D-xylose absorption test. Colorimetry was found to be inferior as compared with NMR due to its low specificity...
- Carbohydrate digestibility and metabolic effectsJulia M W Wong
Clinical Nutrition and Risk Factor Modification Center, St Michael s Hospital, Toronto, Ontario, Canada
J Nutr 137:2539S-2546S. 2007..Therefore, further studies are required to explore these important aspects of metabolism related to the rate of carbohydrate absorption and fermentation and their implications in health and disease...
- Effect of Cryptosporidium parvum infection on the absorptive capacity and paracellular permeability of the small intestine in neonatal calvesPavel Klein
Institute of Animal Science, Pratelstvi 815, Praha Uhrineves, CZ 10401, Czech Republic
Vet Parasitol 152:53-9. 2008..i. In contrast, results of all tests obtained on day 21 p.i. suggest full recovery of the infected intestine. Significantly, growth of the calves which had recovered from cryptosporidiosis was still affected between days 14 and 21 p.i...
- Glucagon-like peptide 2 stimulates intestinal nutrient absorption in parenterally fed newborn pigsP T Sangild
Department of Human Nutrition, Royal Veterinary and Agricultural University, Copenhagen, Denmark
J Pediatr Gastroenterol Nutr 43:160-7. 2006....
- Colonic energy salvage in chronic pancreatic exocrine insufficiencyP M O Owira
GI Clinic and Department of Medicine, University of Cape Town and Groote Schuur Hospital, Cape Town, South Africa
JPEN J Parenter Enteral Nutr 32:63-71. 2008..As a result, increased amounts of undigested nutrients reach the colon, providing more substrate for bacterial fermentation to produce short-chain fatty acids, which could therefore provide additional energy supplement...
- Regression of lactose malabsorption in coeliac patients after receiving a gluten-free dietVeronica Ojetti
Internal Medicine Catholic University, Rome, Italy
Scand J Gastroenterol 43:174-7. 2008..Our aim was to evaluate the effect of a gluten-free diet on lactose malabsorption assessed using the hydrogen lactose breath test (LBT) and also the relationship with normalization of duodenal biopsies in coeliac patients...
- Vitamin B12 deficiency following restorative proctocolectomy: is it really related to surgical procedure?T Sikorski
Colorectal Dis 10:410-1; author reply 411-2. 2008
- Anemia following Roux-en-Y surgery for morbid obesity: a reviewMark A Marinella
Department of Medicine, Division of Hematology Oncology, Wright State University School of Medicine, Dayton, OH 45429, USA
South Med J 101:1024-31. 2008..Since physicians of various medical and surgical specialties are often involved with the postoperative care of bariatric patients, a review of anemia in this patient population is warranted...
- Evaluation of small bowel bacterial overgrowthLawrence R Schiller
Digestive Health Associates of Texas, Baylor University Medical Center, 3500 Gaston Avenue, Dallas, TX 75246, USA
Curr Gastroenterol Rep 9:373-7. 2007..The perfect test for small bowel bacterial overgrowth is yet to be devised...
- Normal or increased bile acid uptake in isolated mucosa from patients with bile acid malabsorptionAntal Bajor
Division of Gastroenterology, Department of Internal Medicine, Sahlgrenska University Hospital, Goteborg, Sweden
Eur J Gastroenterol Hepatol 18:397-403. 2006..Bile acid malabsorption as reflected by an abnormal Se-labelled homocholic acid-taurine (SeHCAT) test is associated with diarrhoea, but the mechanisms and cause-and-effect relations are unclear...
- Ctr1 drives intestinal copper absorption and is essential for growth, iron metabolism, and neonatal cardiac functionYasuhiro Nose
Department of Pharmacology and Cancer Biology, Sarah W Stedman Nutrition and Metabolism Center, Duke University Medical Center, Durham, North Carolina 27710, USA
Cell Metab 4:235-44. 2006..These studies identify Ctr1 as the major factor driving intestinal Cu absorption in mammals...
- Systematic evaluation of the causes of chronic watery diarrhea with functional characteristicsFernando Fernández-Bañares
Department of Gastroenterology, Hospital Universitari Mutua Terrassa, Terrassa, Barcelona, Spain
Am J Gastroenterol 102:2520-8. 2007....
- Exploring possible mechanisms for primary bile acid malabsorption: evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoeaSara Balesaria
Gastroenterology Section, Faculty of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London, UK
Eur J Gastroenterol Hepatol 20:413-22. 2008....
- [Irritable bowl or maldigestion: why is digestion not working properly?]Peter Stiefelhagen
MMW Fortschr Med 150:12-4. 2008
- Vitamin B12 malabsorption in patients with limited ileal resectionDonald R Duerksen
University of Manitoba, Winnipeg, Manitoba, Canada
Nutrition 22:1210-3. 2006..Patients with Crohn's disease who have terminal ileal resections are at risk for vitamin B12 malabsorption. Our aim was to determine whether the length of terminal ileum resected correlated with an abnormal Schilling test result...
- Prednisolone-induced Ca2+ malabsorption is caused by diminished expression of the epithelial Ca2+ channel TRPV6Sylvie Huybers
Department of Physiology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Hilversum Hospital, Nijmegen, The Netherlands
Am J Physiol Gastrointest Liver Physiol 292:G92-7. 2007..In conclusion, these data suggest that prednisolone reduces the intestinal Ca2+ absorption capacity through diminished duodenal expression of the active Ca2+ transporters TRPV6 and calbindin-D(9K) independent of systemic 1,25(OH)2D3...
- Acrodermatitis enteropathica and an overview of zinc metabolismEmanual Maverakis
Department of Dermatology, University of California Davis, Sacramento, CA 95816, USA
J Am Acad Dermatol 56:116-24. 2007..The diagnosis is made by way of clinical presentation together with histopathology and laboratory tests. Here we provide an overview of zinc metabolism and a description of inherited and acquired zinc deficiency...
- The pathology of malabsorption: current conceptsS R Owens
Department of Pathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
Histopathology 50:64-82. 2007..An overview of the most common and interesting entities in each of these categories follows, along with a discussion of current concepts. Mucosal conditions and microbial causes of malabsorption are given special attention...
- Gut hormones, and short bowel syndrome: the enigmatic role of glucagon-like peptide-2 in the regulation of intestinal adaptationG R Martin
Department of Gastrointestinal Sciences, Faculty of Medicine, University of Calgary, 3330 Hospital Drive NW, Calgary, Alberta T2N 4N1, Canada
World J Gastroenterol 12:4117-29. 2006....
- Iron deficiency in childhood and adolescence: retrospective reviewM Ferrara
Department of Pediatrics, The 2nd University of Naples, Naples, Italy
Hematology 11:183-6. 2006..Our findings show that iron replacement therapy was not always required and should not be prescribed until the diagnosis is certain...
- [Functional, microbiological and morphological intestinal findings among human immunodeficiency virus infected children]Christiane Araujo Chaves Leite
Departamento de Pediatria, Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP
Arq Gastroenterol 43:310-5. 2006..Most studies related to this subject were restricted to adults, being less investigated the problem in the children...
- Effect of feeding yogurt versus milk in children with acute diarrhea and carbohydrate malabsorptionG Boudraa
, Amilcar Cabral Clinic, Oran, , France
J Pediatr Gastroenterol Nutr 33:307-13. 2001..Yogurt feeding is associated with a clinically relevant decrease in stool frequency and duration of diarrhea in children who have reducing sugars in stools...
- Role of the pathologist in the differential diagnosis of malabsorptionC Sempoux
Department of Pathology, Cliniques Universitaires St Luc, Brussels, Belgium
Acta Gastroenterol Belg 69:49-51. 2006Histological examination of small intestinal biopsies is an essential step in the assessment of malabsorption syndromes. Multiple biopsies should be taken in the proximal jejunum or distal duodenum and correctly oriented...
- Serum and intestinal dipeptidyl peptidase IV (DPP IV/CD26) activity in children with celiac diseaseDijana Detel
Department of Chemistry and Biochemistry, School of Medicine, University of Rijeka, Croatia
J Pediatr Gastroenterol Nutr 45:65-70. 2007..The aim of this study was to examine the possible causal connection between DPP IV enzyme activities and celiac disease (CD) in children...
- Hematological response to short-term oral cyanocobalamin therapy for the treatment of cobalamin deficiencies in elderly patientsE Andres
Department of Internal Medicine, Hopitaux Universitaires de Strasbourg, 67 091 Strasbourg Cedex, France
J Nutr Health Aging 10:3-6. 2006..The aim of this trial was to demonstrate the efficacy of one month of oral cobalamin (vitamin B12) therapy in elderly patients with cobalamin deficiency related to food-cobalamin malabsorption (FCM)...
- Urinary patterns of patients with renal stones associated with chronic inflammatory bowel diseaseAlberto Trinchieri
Institute of Urology, IRCCS Ospedale Maggiore, Milano, Italy
Arch Ital Urol Androl 74:61-4. 2002..The aim of this study was to analyze the frequency of renal stone patients with chronic inflammatory bowel disease and their urinary patterns...
- Carbohydrate malabsorption may increase daily energy requirements in infantsSandra Valois
EMTAC Inc, Miami, Florida 33134, USA
Nutrition 19:832-6. 2003..However, the effect of this alteration on daily metabolic rate is unknown. We assessed daily metabolic rates in infants with asymptomatic carbohydrate malabsorption (ACM) after a single fruit juice load...
- The role of the intestine in bone homeostasisJulian R Walters
Faculty of Medicine, Imperial College London, London W12 0NN, UK
Eur J Gastroenterol Hepatol 15:845-9. 2003..Bone changes are found in many intestinal disorders including lactose intolerance, coeliac disease, short bowel syndrome, small intestinal bacterial overgrowth and Crohn's disease...
- Enteric bacterial flora and bacterial overgrowth syndromeClark R Gregg
Medical Service, Veterans Affairs, North Texas Health Care System, Dallas 75216, USA
Semin Gastrointest Dis 13:200-9. 2002..Improvements on this approach to SBBOS will be built on more widespread access to sensitive, specific, and less cumbersome testing than is currently available...
- Malabsorption syndromesGiuseppe Salerno
Istituto di Radiologia, Universita Cattolica del S Cuore, Policlinico A Gemelli, Largo A Gemelli 8, 00168 Roma, Italy
Rays 27:19-34. 2002b>Malabsorption syndromes are divided according to the underlying cause: maldigestion; bacterial contamination; mucosal abnormalities. One of the main causes of maldigestion are surgical resections...
- Small bowel diseasesItalo De Vitis
Istituto di Medicina Interna, Universià Cattolica del S Cuore, Policlinico A Gemelli, Largo A Gemelli 8, 00168 Roma, Italy
Rays 27:3-10. 2002The study of small bowel disease is hampered by the organ length and shape. Malabsorption syndromes, small bowel bleeding, intestinal obstruction are analyzed with reference to the clinical characteristics and present laboratory and ..
- Labeled acetate to assess intestinal absorption in critically ill patientsRené L Chioléro
Surgical Intensive Care Unit Department of Surgery, University Hospital CHUV, Lausanne, Switzerland
Crit Care Med 31:853-7. 2003..To compare the absorption of carbon-13(13C) acetate-enriched nutrients with D-xylose absorption...
- Bile acid malabsorption or disturbed intestinal permeability in patients treated with enzyme substitution for exocrine pancreatic insufficiency is not caused by bacterial overgrowthJan Lysgård Madsen
Department of Clinical Physiology and Nuclear Medicine, Hvidovre Hospital, Denmark
Pancreas 26:130-3. 2003..Therefore, other mechanisms separately or in interplay with reduced enzyme secretion might be responsible for malabsorption in these patients...
- Overview and diagnosis of malabsorption syndromeJames J Farrell
Division of Digestive Diseases, UCLA School of Medicine, UCLA Center for the Health Science, Los Angeles, CA 90095, USA
Semin Gastrointest Dis 13:182-90. 2002..This review discusses the etiology and pathophysiology of malabsorption. A diagnostic approach to malabsorption is proposed. Other articles review specific disorders such as celiac disease, bacterial overgrowth, and chronic pancreatitis...
- Malnutrition and gastrointestinal diseaseDarren A Kastin
Division of Gastroenterology and Hepatology, Northwestern University Medical School, Chicago, Illinois 60611, USA
Curr Opin Clin Nutr Metab Care 5:699-706. 2002..Selected topics including celiac disease, disaccharidase deficiencies, short bowel syndrome, and Crohn disease are discussed...
- Histologic follow-up of people with celiac disease on a gluten-free diet: slow and incomplete recoveryPeter J Wahab
Department of Gastroenterology and Hepatology, Rijnstate Hospital Arnhem, The Netherlands
Am J Clin Pathol 118:459-63. 2002..1% villous atrophy after 5 years). Systematic follow-up of patients with celiac disease and the malabsorption syndrome and secondary complications is needed...
- Chronic diarrhea and malabsorption (including short gut syndrome): Working Group Report of the First World Congress of Pediatric Gastroenterology, Hepatology, and NutritionJohn Walker-Smith
Commonwealth Association of Paediatric Gastroenterology and Nutrition, USA
J Pediatr Gastroenterol Nutr 35:S98-105. 2002
- Small bowel disease in the elderly: diarrhoea and malabsorptionJorg C Hoffmann
Medizinische Klinik I mit Schwerpunkt Gastroenterologie, Infektiologie, Rheumatologie, Universitatsklinikum Benjamin Franklin, Berlin, Germany
Best Pract Res Clin Gastroenterol 16:17-36. 2002..The careful diagnostic work-up must aim at the identification of treatable disorders such as coeliac disease, Crohn's disease and bacterial overgrowth. Often, a detailed drug history is of help in identifying a readily treatable cause...
- Beneficial effect of goat milk on nutritive utilization of iron and copper in malabsorption syndromeM Barrionuevo
Department of Physiology, Faculty of Pharmacy, University of Granada, Spain
J Dairy Sci 85:657-64. 2002..This study shows the beneficial effect of goat milk, with respect to cow milk, on the metabolism of iron and copper in control rats, especially those with malabsorption syndrome...
- 2011 Mechanisms of Membrane Transport Gordon Research ConferenceNancy Carrasco; Fiscal Year: 2011..of these proteins will lead to better understanding of normal function, of diseases like hypertension, malabsorption syndromes, and cystic fibrosis, and to development of new and improved therapeutic agents...
- Vitamin D Production by Sperti Lamp in Fat Malabsorption PatientsJAMES GAMBLE SHEPHERD; Fiscal Year: 2010..the commercial development of this novel vitamin D producing fluorescent lamp not only for patients with malabsorption syndromes but also elderly in nursing homes and for children and adults who cannot be exposed to sunlight and have ..
- Myosin Functions in the EnterocyteMark S Mooseker; Fiscal Year: 2010..essential to understand human diseases of the intestine including inflammatory bowel disease and malabsorption syndromes. Moreover, many myosins are targets for human diseases, including 2 of the 3 to be investigated.
- 2013 MECHANISMS OF MEMBRANE TRANSPORT GRCNancy Carrasco; Fiscal Year: 2013..of a host of vital molecules, but also for the development of new therapeutic agents and approaches to a wide variety of diseases, including hypertension, depression, hypothyroidism, malabsorption syndromes, and cystic fibrosis.
- 2014 Ligand Recognition and Molecular Gating Gordon Research ConferenceCrina M Nimigean; Fiscal Year: 2013..proteins will lead to better understanding of normal function, of diseases like epilepsy, hypertension, malabsorption syndromes, cystic fibrosis, and to development of new and improved therapeutic agents...
- The Drosophila midgut: A model of human intestinal stem cells and their progeny.Benjamin Ohlstein; Fiscal Year: 2013..Therefore the results of our research should provide valuable insights into the pathogenesis of human digestive disorders such as intestinal cancers, malabsorption syndromes, and diabetes.
- THE TRANSPORT OF CALCIUMDavid Schachter; Fiscal Year: 1991..These studies should contribute to an understanding of a number of human disorders including malabsorption syndromes, metabolic bone disorders and cardiovascular diseases such as essential hypertension.
- MOLECULAR UNDERSTANDING OF INTESTINAL PROLINE TRANSPORTBRUCE STEVENS; Fiscal Year: 1990..for understanding ion-coupled and ion-independent solute transport, and thus will enhance the understanding of the membrane pathophysiology of genetic defects of amino acid transport in intestinal and renal malabsorption syndromes.
- INTESTINAL ABSORPTION OF LIPIDSALFRED RAMPONE; Fiscal Year: 1980..entities associated with excessive intake, absorption or excessive blood levels such as obesity and hypercholesterolemia or 2) enhancing their absorption in cases where this is desirable such as malabsorption syndromes and malnutrition.
- FATTY ACID ASSIMILATION IN THE INTESTINEJudith Storch; Fiscal Year: 1991..of ffa assimilation at the molecular level will enable more effective treatment of several pathophysiological and drug-induced malabsorption syndromes, and will support the continued development of oral drug delivery systems.
- MOLECULAR ARCHITECTURE OF THE NA+/GLUCOSE COTRANSPORTERERNEST WRIGHT; Fiscal Year: 2005..coli, purified and reconstituted into liposomes. The results will provide a direct test of the alternating access model for sodium/sugar cotransport. ..
- FAMILIAL GLUCOSE GALACTOSE MALABSORPTIONERNEST WRIGHT; Fiscal Year: 2001..This study will enable us to identify and treat patients with sugar malabsorption due to mutations in the SGLT1 gene, and will provide unique information about the synthesis, trafficking and function of the cotransporter. ..
- Oleic Acid Effects on Transit and Absorption in SBSCharlene Compher; Fiscal Year: 2004....
- SUBTLE DISTURBANCES OF COBALAMIN STATUSRalph Carmel; Fiscal Year: 2007..unreadable] [unreadable]..
- CNS defects in a murine Zellweger syndrome modelPhyllis Faust; Fiscal Year: 2007....
- Use of symbiotics to reduce urinary oxalate excretionJOHN LIESKE; Fiscal Year: 2007..If results are positive, treatment for calcium oxalate kidney stones could be revolutionized. ..
- Hyperoxaluria and Nephrolithiasis After Gastric Bypass Surgery for ObesityRajiv Kumar; Fiscal Year: 2008..Finally, we will study why these complications occur and we will develop ways in which to prevent kidney stones and loss of kidney function after gastric bypass surgery. [unreadable] [unreadable] [unreadable]..
- Nephrolithiasis and Chronic Kidney DiseaseJOHN LIESKE; Fiscal Year: 2007..This will gain additional urgency if in fact we demonstrate that NL is a significant risk factor for CKD. [unreadable] [unreadable] [unreadable]..
- Nutritional Status In HIV Hispanic Drug AbusersJanet Forrester; Fiscal Year: 2008..The proposed study will build on the infrastructure of the BIENESTAR study (NIDA DA 11598) and the BIENESTAR-micronutrient study (NIDA DA 14501). ..
- THE PHYSIOLOGY AND METABOLISM OF VITAMIN DRajiv Kumar; Fiscal Year: 2003..Results of this investigation could lead to a better understanding of the pathogenesis of bone diseases and the formulation of new therapeutic strategies in disorders such as hyperparathyroidism and osteoporosis. ..
- ALPHA 2 ADRENERGIC CONTROL IN IRRITABLE BOWEL SYNDROMEMichael Camilleri; Fiscal Year: 2008..Significance: This project will characterize pharmacogenetic mechanisms determining the response to clonidine through studies of candidate genes that control alpha2-adrenoreceptor function and norepinephrine transport in IBS. ..
- Prevention of Postmenopausal Bone Loss with Nitric OxideSunil Wimalawansa; Fiscal Year: 2007..The study will also pave the way for the future, for providing more acceptable, affordable and cost- effective therapies for the prevention of postmenopausalosteoporosis. ..
- Epidemiology of Celiac Disease: A Population Based StudyJoseph A Murray; Fiscal Year: 2010..This will provide crucial data that will determine the need for early detection by screening and treatment of silent celiac disease, which may affect 1% of Americans. ..
- A HLA Mouse Model for Gluten Sensitivity and EnteropathyJoseph Murray; Fiscal Year: 2009..abstract_text> ..
- Cdx2 modulates beta-catenin activity in intestinal cellsJohn P Lynch; Fiscal Year: 2010..As a result, potential novel targeted therapeutics mayalso emerge. ..
- Cannabinoid Mechanisms in Human Gastrointestinal Motor and Sensory FunctionsMICHAEL L CAMILLERI; Fiscal Year: 2010..These actions may be relevant to develop new treatments for IBS. The studies will also provide further understanding of the potential of medications like medical marijuana on stomach function that may be relevant to appetite control. ..
- Mechanisms for differential effects of dietary fatty acids on metabolismCRAIG LAWRENCE KIEN; Fiscal Year: 2010..important new information regarding how mitochondrial malfunction, modified by dietary FA, plays a central role in the development of obesity, the metabolic syndrome, type 2 diabetes, and both heritable and age-related metabolic diseases ..
- Cell Fate Determination of the Intestine and Chronic Diarrhea in ChildrenMartin Martin; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Biology of a Novel Phosphaturic Protein - sFRP-4Rajiv Kumar; Fiscal Year: 2007..Our findings will have important implications with respect to Pi homeostasis, bone mineralization in mammals and humans, and the regulation of ion transport through Wnt signaling in the kidney. ..
- NUTRITIONAL STATUS OF CF PULMONARY DISEASEVirginia Stallings; Fiscal Year: 2001..These data will provide the scientific basis for early and effective nutritional intervention to promote normal growth and body composition as standard CF care. ..
- BIOLOGY OF HUMAN INTRAEPITHELIAL LYMPHOCYTESEllen Ebert; Fiscal Year: 2002..These studies will determine the mechanism of IEL chemotaxis toward secreted products of ECs, why IL-15 is more potent than IL-2 in inducing LAK activity by IELs, and how IL-10 and IL-12 augment this activity. ..
- Androgen deficiency and Osteopenia in Anorexia NervosaKaren Miller; Fiscal Year: 2002..In the third phase of the study, we will examine the effects of administering testosterone on bone density and body mass. ..
- CNS DEFECT IN A MURINE ZELLWEGER SYNDROME MODELPhyllis Faust; Fiscal Year: 2002....
- Regulation of Intestinal Nutrient TransportersMartin Martin; Fiscal Year: 2002..The identification and further characterization of these cis elements will provide better insight into the molecular mechanism of enterocyte-specific cell fate and the various factors mediating its regulation. ..
- Oxalate-Induced Renal Scarring and Crystal RetentionJOHN LIESKE; Fiscal Year: 2003..Dr. Luis Juncos has extensive experience studying the regulation of renal blood flow in vivo, and will be critical in our efforts to develop the constant infusion model of hyperoxalemia and hyperoxaluria. ..
- REGULATION OF INTESTINAL EPITHELIAL CELL PROLIFERATIONJohn Lynch; Fiscal Year: 2004..It will also enhance our understanding of the events leading to dysregulation of proliferation and human colon cancers. ..
- Micronutrient Metabolism in HIV+and HIV-Drug UsersJanet Forrester; Fiscal Year: 2004..The long term goal of this research is to develop effective interventions to improve the nutritional status and health outcomes of drug abusers with and without infectious diseases, including HIV. ..
- Permeability Changes in Small Bowel Allograft RejectionJonathan Fryer; Fiscal Year: 2006....
- Role of Nanobacteria in Human Calcifying DiseaseJOHN LIESKE; Fiscal Year: 2004..abstract_text> ..
- DIFFERENTIAL METABOLISM OF DIETARY FATTY ACIDSCRAIG KIEN; Fiscal Year: 2003..In specific aim 4, the PI will measure the thermic effect of feeding during both the solid food and formula diet periods. The PI hypothesizes that the high OA feeding will be associated with a higher thermic effect of feeding. ..
- Colonic Bacterial Synthesis of Butyric AcidCRAIG KIEN; Fiscal Year: 2004....
- Mechanisms of Adaptation in Human Short Bowel SyndromeThomas Ziegler; Fiscal Year: 2005..abstract_text> ..
- NOVEL INHIBITOR OF CRYSTAL ADHESION TO RENAL CELLSJOHN LIESKE; Fiscal Year: 2004..Achieving these specific aims will provide new knowledge about mechanisms that mediate stone formation, and provide a rational basis for design of novel strategies to treat and/or prevent this disease. ..
- MOLECULAR BASIS OF ENTEROCYTE REGULATION DURING ONTOGENYMartin Martin; Fiscal Year: 2002..Analysis of the FcRn and pIgR genes offers a unique model that may lead to a better understanding of the molecular mechanism of intestinal ontogeny, and specifically the intrinsic clock which controls its regulation. ..
- ALPHA-2 ADRENERGIC CONTROL OF COLONIC FUNCTION IN IBSMichael Camilleri; Fiscal Year: 2007..abstract_text> ..
- STRUCTURE/ACTIVITY STUDIES OF NPYAmbikaipakan Balasubramaniam; Fiscal Year: 2001..These analogs will have great significance both in fundamental studies as well as in the development of therapeutic drugs for a variety of conditions including feeding disorders and hypertension. ..
- REGULATIOIN OF RENAL PHOSPHATE EXCRETION AND VITAMIN D METABOLISM BY FGF 7Rajiv Kumar; Fiscal Year: 2010..The interaction between the FGF 7 and other PTNs will be clarified. Such information will significantly enhance our knowledge of mineralization processes and Pi homeostasis. ..
- THE STRUCTURE OF CALBINDIN-D28KRajiv Kumar; Fiscal Year: 2004..These findings will potentially be of significance in the understanding of neurodegenerative disorders, cerebellar function and long-term hippocampal potentiation. ..
- DIET/GROWTH FACTOR MECHANISMS OF GUT ADAPTATIONThomas Ziegler; Fiscal Year: 2004....
- EXPRESSION AND STRUCTURE OF THE CALCIUM SENSING RECEPTORRajiv Kumar; Fiscal Year: 2007..Furthermore, this information will serve as the basis for more extensive experiments involving the structure of the full-length receptor. [unreadable] [unreadable]..