carpal tunnel syndrome

Summary

Summary: Entrapment of the MEDIAN NERVE in the carpal tunnel, which is formed by the flexor retinaculum and the CARPAL BONES. This syndrome may be associated with repetitive occupational trauma (CUMULATIVE TRAUMA DISORDERS); wrist injuries; AMYLOID NEUROPATHIES; rheumatoid arthritis (see ARTHRITIS, RHEUMATOID); ACROMEGALY; PREGNANCY; and other conditions. Symptoms include burning pain and paresthesias involving the ventral surface of the hand and fingers which may radiate proximally. Impairment of sensation in the distribution of the median nerve and thenar muscle atrophy may occur. (Joynt, Clinical Neurology, 1995, Ch51, p45)

Top Publications

  1. ncbi Associations between work-related factors and the carpal tunnel syndrome--a systematic review
    Rogier M van Rijn
    Erasmus MC, Department of General Practice, Room Wk 109, PO Box 2040, NL 3000 CA Rotterdam, Netherlands
    Scand J Work Environ Health 35:19-36. 2009
  2. ncbi Prevalence of carpal tunnel syndrome in a general population
    I Atroshi
    Department of Orthopedics, Hässleholm Kristianstad Hospital, Sweden
    JAMA 282:153-8. 1999
  3. doi Carpal tunnel syndrome and musculoskeletal symptoms in postmenopausal women with early breast cancer treated with exemestane or tamoxifen after 2-3 years of tamoxifen: a retrospective analysis of the Intergroup Exemestane Study
    J Sven D Mieog
    Department of Surgery, Leiden University Medical Center, Leiden, Netherlands
    Lancet Oncol 13:420-32. 2012
  4. pmc Hypothalamus and amygdala response to acupuncture stimuli in Carpal Tunnel Syndrome
    V Napadow
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States
    Pain 130:254-66. 2007
  5. ncbi Yoga-based intervention for carpal tunnel syndrome: a randomized trial
    M S Garfinkel
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA
    JAMA 280:1601-3. 1998
  6. ncbi Treatment of carpal tunnel syndrome with alpha-lipoic acid
    G Di Geronimo
    UO Chirurgia della Mano e dei Nervi Periferici, Presidio Ospedaliero dei Pellegrini, Napoli, Italy
    Eur Rev Med Pharmacol Sci 13:133-9. 2009
  7. doi Brief post-surgical electrical stimulation accelerates axon regeneration and muscle reinnervation without affecting the functional measures in carpal tunnel syndrome patients
    Tessa Gordon
    Division of Physical Medicine and Rehabilitation Center for Neuroscience, University of Alberta, 525 Heritage Medical Research Centre, Edmonton, Alberta, Canada T6G 2S2
    Exp Neurol 223:192-202. 2010
  8. ncbi A case-control study of obesity as a risk factor for carpal tunnel syndrome in a population of 600 patients presenting for independent medical examination
    S P Stallings
    Department of Surgery, University of Louisville School of Medicine, KY, USA
    J Hand Surg Am 22:211-5. 1997
  9. ncbi Repetitive strain injury
    Maurits van Tulder
    Institute for Research in Extramural Medicine, VU University Medical Centre, Amsterdam, Netherlands
    Lancet 369:1815-22. 2007
  10. ncbi Switch from conventional to high-flux membrane reduces the risk of carpal tunnel syndrome and mortality of hemodialysis patients
    Y Koda
    Kidney Center of Shinraku en Hospital, Niigata University, School of Medicine, Japan
    Kidney Int 52:1096-101. 1997

Detail Information

Publications348 found, 100 shown here

  1. ncbi Associations between work-related factors and the carpal tunnel syndrome--a systematic review
    Rogier M van Rijn
    Erasmus MC, Department of General Practice, Room Wk 109, PO Box 2040, NL 3000 CA Rotterdam, Netherlands
    Scand J Work Environ Health 35:19-36. 2009
    The aim of this study was to make a quantitative assessment of the exposure-response relationships between work-related physical and psychosocial factors and the occurrence of carpal tunnel syndrome (CTS) in occupational populations.
  2. ncbi Prevalence of carpal tunnel syndrome in a general population
    I Atroshi
    Department of Orthopedics, Hässleholm Kristianstad Hospital, Sweden
    JAMA 282:153-8. 1999
    b>Carpal tunnel syndrome (CTS) is a cause of pain, numbness, and tingling in the hands and is an important cause of work disability...
  3. doi Carpal tunnel syndrome and musculoskeletal symptoms in postmenopausal women with early breast cancer treated with exemestane or tamoxifen after 2-3 years of tamoxifen: a retrospective analysis of the Intergroup Exemestane Study
    J Sven D Mieog
    Department of Surgery, Leiden University Medical Center, Leiden, Netherlands
    Lancet Oncol 13:420-32. 2012
    ..of breast-cancer recurrence, but at the expense of increased musculoskeletal side-effects, such as carpal tunnel syndrome. The aim of this study was to assess risk factors and the prognostic value of musculoskeletal symptoms ..
  4. pmc Hypothalamus and amygdala response to acupuncture stimuli in Carpal Tunnel Syndrome
    V Napadow
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, United States
    Pain 130:254-66. 2007
    ..We used fMRI to evaluate verum and sham acupuncture stimulation at acupoint LI-4 in Carpal Tunnel Syndrome (CTS) patients and healthy controls (HC). CTS patients were retested after 5 weeks of acupuncture therapy...
  5. ncbi Yoga-based intervention for carpal tunnel syndrome: a randomized trial
    M S Garfinkel
    Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, USA
    JAMA 280:1601-3. 1998
    b>Carpal tunnel syndrome is a common complication of repetitive activities and causes significant morbidity.
  6. ncbi Treatment of carpal tunnel syndrome with alpha-lipoic acid
    G Di Geronimo
    UO Chirurgia della Mano e dei Nervi Periferici, Presidio Ospedaliero dei Pellegrini, Napoli, Italy
    Eur Rev Med Pharmacol Sci 13:133-9. 2009
    b>Carpal Tunnel Syndrome (CTS) is the most common peripheral mononeuropathy; its symptoms and functional limitations significantly penalize the daily activities and quality of life of many people...
  7. doi Brief post-surgical electrical stimulation accelerates axon regeneration and muscle reinnervation without affecting the functional measures in carpal tunnel syndrome patients
    Tessa Gordon
    Division of Physical Medicine and Rehabilitation Center for Neuroscience, University of Alberta, 525 Heritage Medical Research Centre, Edmonton, Alberta, Canada T6G 2S2
    Exp Neurol 223:192-202. 2010
    ..Other outcome measures showed a significant improvement in both patient groups. We conclude that brief low frequency ES accelerates axonal regeneration and target reinnervation in humans...
  8. ncbi A case-control study of obesity as a risk factor for carpal tunnel syndrome in a population of 600 patients presenting for independent medical examination
    S P Stallings
    Department of Surgery, University of Louisville School of Medicine, KY, USA
    J Hand Surg Am 22:211-5. 1997
    Pain, numbness, and tingling through the median nerve distribution, known as carpal tunnel syndrome (CTS), has been associated with many personal risk factors...
  9. ncbi Repetitive strain injury
    Maurits van Tulder
    Institute for Research in Extramural Medicine, VU University Medical Centre, Amsterdam, Netherlands
    Lancet 369:1815-22. 2007
    ..The term repetitive strain injury includes specific disorders such as carpal tunnel syndrome, cubital tunnel syndrome, Guyon canal syndrome, lateral epicondylitis, and tendonitis of the wrist or hand...
  10. ncbi Switch from conventional to high-flux membrane reduces the risk of carpal tunnel syndrome and mortality of hemodialysis patients
    Y Koda
    Kidney Center of Shinraku en Hospital, Niigata University, School of Medicine, Japan
    Kidney Int 52:1096-101. 1997
    ..To examine the membrane effect as a factor of carpal tunnel syndrome onset and mortality, multivariate Cox regression analysis with time-dependent covariate was conducted on ..
  11. pmc Risk factors for operated carpal tunnel syndrome: a multicenter population-based case-control study
    Stefano Mattioli
    Occupational Health Service, ASL di Ravenna, Ravenna, Italy
    BMC Public Health 9:343. 2009
    b>Carpal tunnel syndrome (CTS) is a socially and economically relevant disease caused by compression or entrapment of the median nerve within the carpal tunnel...
  12. ncbi A neurophysiological grading scale for carpal tunnel syndrome
    J D Bland
    Kent and Canterbury Hospital, Canterbury, Kent, England
    Muscle Nerve 23:1280-3. 2000
    Different ways of expressing the severity of carpal tunnel syndrome (CTS) are found in the existing literature and in clinical records...
  13. ncbi Evaluation of age, body mass index, and wrist index as risk factors for carpal tunnel syndrome severity
    Joao A Kouyoumdjian
    Department of Neurological Sciences, State Medical School, Av Bady Bassitt 3896, 15025 000 Sao Jose Rio Preto, Sao Paulo, Brazil
    Muscle Nerve 25:93-7. 2002
    To determine the role of personal variables as risk factors for carpal tunnel syndrome (CTS) and their relationship to severity of nerve conduction abnormality, we studied 210 consecutive symptomatic CTS patients and 320 controls subjects ..
  14. ncbi An evaluation of gender, obesity, age and diabetes mellitus as risk factors for carpal tunnel syndrome
    Jefferson Becker
    Department of Clinical Neurophysiology, Hospital Luterano, Universidade Luterana do Brasil, RS, Porto Alegre, Brazil
    Clin Neurophysiol 113:1429-34. 2002
    ..gender, high body mass index (BMI), age and diabetes mellitus (DM) as independent risk factors (RF) for carpal tunnel syndrome (CTS) and to analyse the strength of association of these factors, both globally and in individual ..
  15. doi The quality and strength of evidence for etiology: example of carpal tunnel syndrome
    Santiago Lozano-Calderon
    Department of Orthopaedic Surgery, Hand and Upper Extremity Service, Massachusetts General Hospital, Boston, MA, USA
    J Hand Surg Am 33:525-38. 2008
    ....
  16. ncbi Performance of a high-repetition, high-force task induces carpal tunnel syndrome in rats
    Brian D Clark
    Department of Physical Therapy, Temple University, Philadelphia, PA 19140, USA
    J Orthop Sports Phys Ther 34:244-53. 2004
    ..A randomized controlled prospective experimental study with some repeated measures...
  17. pmc Carpal tunnel syndrome
    Somaiah Aroori
    Department of Surgery, Level 2, Belfast HSC Trust, Lisburn Road, Belfast BT9 7AB, United Kingdom
    Ulster Med J 77:6-17. 2008
    b>Carpal tunnel syndrome is one of the most common peripheral neuropathies. It affects mainly middle aged women. In the majority of patients the exact cause and pathogenesis of CTS is unclear...
  18. ncbi Carpal tunnel syndrome modifies sensory hand cortical somatotopy: a MEG study
    Franca Tecchio
    IFN CNR, Rome, Italy
    Hum Brain Mapp 17:28-36. 2002
    ..In the present study the effects of carpal tunnel syndrome (CTS) are investigated as reflected on the somatotopy of the primary cortical hand representation...
  19. ncbi Practice parameter: Electrodiagnostic studies in carpal tunnel syndrome. Report of the American Association of Electrodiagnostic Medicine, American Academy of Neurology, and the American Academy of Physical Medicine and Rehabilitation
    C K Jablecki
    American Association of Electrodiagnostic Medicine, 421 First Avenue SW, Suite 300 East, Rochester, MN 55902, USA
    Neurology 58:1589-92. 2002
  20. doi Carpal tunnel syndrome. Part I: effectiveness of nonsurgical treatments--a systematic review
    Bionka M Huisstede
    Department of General Practice, Erasmus Medical Center, Rotterdam, The Netherlands
    Arch Phys Med Rehabil 91:981-1004. 2010
    To review literature systematically concerning effectiveness of nonsurgical interventions for treating carpal tunnel syndrome (CTS).
  21. ncbi Somatosensory cortical plasticity in carpal tunnel syndrome treated by acupuncture
    Vitaly Napadow
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Hum Brain Mapp 28:159-71. 2007
    b>Carpal tunnel syndrome (CTS) is a common entrapment neuropathy of the median nerve characterized by paresthesias and pain in the first through fourth digits...
  22. ncbi Risk factors in carpal tunnel syndrome
    J M Geoghegan
    Department of Trauma and Orthopaedics, Derbyshire Royal Infirmary, Derby, UK
    J Hand Surg Br 29:315-20. 2004
    ..General Practice Research Database to quantify the relative contributions of the common risk factors for carpal tunnel syndrome (CTS) in the community...
  23. pmc Consensus criteria for the classification of carpal tunnel syndrome in epidemiologic studies
    D Rempel
    School of Medicine, University of California, San Francisco, USA
    Am J Public Health 88:1447-51. 1998
    Criteria for the classification of carpal tunnel syndrome for use in epidemiologic studies were developed by means of a consensus process...
  24. pmc Incidence of common compressive neuropathies in primary care
    R Latinovic
    Department of Public Health Sciences, King s College London, London SE1 1UL, UK
    J Neurol Neurosurg Psychiatry 77:263-5. 2006
    Apart from carpal tunnel syndrome, there are no population based studies of the epidemiology of compressive neuropathies...
  25. ncbi Prevalence, incidence and risk factors of carpal tunnel syndrome in a large footwear factory
    Y Roquelaure
    Center for Occupational Health and Ergonomics, University Hospital, Angers, France
    Int J Occup Med Environ Health 14:357-67. 2001
    The study was conducted to assess the prevalence and incidence of carpal tunnel syndrome (CTS) in a large modern footwear factory and to identify factors predictive of CTS...
  26. ncbi Anatomic distribution of sensory symptoms in the hand and their relation to neck pain, psychosocial variables, and occupational activities
    Isabel Reading
    MRC Environmental Epidemiology Unit, University of Southampton, Southampton, England
    Am J Epidemiol 157:524-30. 2003
    ..and tingling in the hand can be usefully distinguished in epidemiologic studies of disorders such as carpal tunnel syndrome, the authors used a postal questionnaire, an interview, and a physical examination to collect information ..
  27. ncbi Treatment of carpal tunnel syndrome with nerve and tendon gliding exercises
    Elif Akalin
    Department of Physical Medicine and Rehabilitation, Dokuz Eylul University, Izmir, Turkey
    Am J Phys Med Rehabil 81:108-13. 2002
    To assess the effect of nerve and tendon gliding exercises in carpal tunnel syndrome.
  28. ncbi Lifetime risk of symptomatic carpal tunnel syndrome in Type 1 diabetes
    R Singh
    Auckland Diabetes Centre, Auckland, New Zealand
    Diabet Med 22:625-30. 2005
    To determine the lifetime risk of developing symptomatic carpal tunnel syndrome (CTS) in subjects with Type 1 diabetes and to investigate the effect of glycaemic control, body mass index (BMI), gender and age of onset of diabetes.
  29. ncbi Carpal tunnel syndrome: the correlation between outcome, symptoms and nerve conduction study findings
    L Longstaff
    Department of Plastic Surgery, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    J Hand Surg Br 26:475-80. 2001
    ..Furthermore, no relationship could be identified between pre-operative nerve conduction impairment and either successful outcome of surgery (defined as complete symptom relief) or time to resolution of symptoms after surgery...
  30. ncbi Responsiveness of the Michigan Hand Outcomes Questionnaire and the Disabilities of the Arm, Shoulder and Hand questionnaire in carpal tunnel surgery
    Sandra V Kotsis
    Section of Plastic Surgery, Department of Surgery, The University of Michigan Health System, 1500 E Medical Center Drive, 2130 Taubman Center, Ann Arbor, MI 48109 0340, USA
    J Hand Surg Am 30:81-6. 2005
    Symptom resolution and functional improvement are the 2 primary reasons for patients to seek treatment for carpal tunnel syndrome (CTS)...
  31. ncbi The value of the history in the diagnosis of carpal tunnel syndrome
    J D Bland
    EEG Department, Kent and Canterbury Hospital, Kent, UK
    J Hand Surg Br 25:445-50. 2000
    Details of the clinical history were elicited by questionnaire from 8,223 patients with suspected carpal tunnel syndrome and compared with the neurophysiological findings...
  32. ncbi Prediction of the neurophysiological diagnosis of carpal tunnel syndrome from the demographic and clinical data
    Irenio Gomes
    Neurology Service, Hospital Sao Lucas da PUCRS, Porto Alegre, Brazil
    Clin Neurophysiol 117:964-71. 2006
    To use demographic and clinical data to identify the clinical pattern that best predicts the diagnosis of carpal tunnel syndrome (CTS), as defined by neurophysiologic studies.
  33. doi Functional sensibility assessment. Part II: Effects of sensory improvement on precise pinch force modulation after transverse carpal tunnel release
    Hsiu Yun Hsu
    Department of Physical Medicine and Rehabilitation, National Cheng Kung University, Tainan, 701 Taiwan
    J Orthop Res 27:1534-9. 2009
    ..We analyzed precision grip function after the sensory recovery of patients with carpal tunnel syndrome (CTS) who underwent carpal tunnel release (CTR)...
  34. ncbi The use of diagnostic ultrasound in carpal tunnel syndrome
    Ethan R Wiesler
    Department of Orthopaedic Surgery, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    J Hand Surg Am 31:726-32. 2006
    Traditional evaluation of suspected carpal tunnel syndrome (CTS) involves a thorough history, physical examination, and nerve conduction velocity studies (NCS)...
  35. doi The effectiveness of conservative treatments of carpal tunnel syndrome: splinting, ultrasound, and low-level laser therapies
    Umit Dincer
    Department of Physical Medicine and Rehabilitation, Gulhane Military Medical Academy, Haydarpasa Training Hospital, Istanbul, Turkey
    Photomed Laser Surg 27:119-25. 2009
    The objective of this study was to investigate the effectiveness of splinting, ultrasound (US), and low-level laser (LLL) in the management of carpal tunnel syndrome (CTS).
  36. doi The value added by electrodiagnostic testing in the diagnosis of carpal tunnel syndrome
    Brent Graham
    Hand Program, Toronto Western Hospital, 399 Bathurst Street, East Wing 2 425, Toronto, ON M5T 2S8, Canada
    J Bone Joint Surg Am 90:2587-93. 2008
    There is no clear-cut consensus on the best diagnostic criteria for carpal tunnel syndrome. The objective of this study was to compare the probability of carpal tunnel syndrome being present following electrodiagnostic testing with the ..
  37. pmc Symptoms, signs and nerve conduction velocities in patients with suspected carpal tunnel syndrome
    Georgia Ntani
    MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton SO16 6YD, UK
    BMC Musculoskelet Disord 14:242. 2013
    To inform the clinical management of patients with suspected carpal tunnel syndrome (CTS) and case definition for CTS in epidemiological research, we explored the relation of symptoms and signs to sensory nerve conduction (SNC) ..
  38. ncbi Discriminatory sonographic criteria for the diagnosis of carpal tunnel syndrome
    S M Wong
    Department of Medicine, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Arthritis Rheum 46:1914-21. 2002
    ..median nerve has been suggested as a useful alternative to electrophysiologic study in the diagnosis of carpal tunnel syndrome. To determine its usefulness and the best diagnostic criterion, sonograms of patients with the disease ..
  39. doi Pain and motor function in carpal tunnel syndrome: a clinical, neurophysiological and psychophysical study
    S Tamburin
    Dept of Neurological Sciences and Vision, Section of Neurological Rehabilitation, University of Verona, Verona, Italy
    J Neurol 255:1636-43. 2008
    Patients with carpal tunnel syndrome (CTS) complain of motor symptoms. The study is aimed to understand which features are associated with the presence of motor symptoms in CTS.
  40. ncbi Ultrasonography versus nerve conduction study in patients with carpal tunnel syndrome: substantive or complementary tests?
    Y M El Miedany
    Darent Valley Hospital, Dartford, Kent DA2 8DA, UK
    Rheumatology (Oxford) 43:887-95. 2004
    ..to assess the optimal discriminatory sonographic criteria and relevant threshold values in patients with carpal tunnel syndrome (CTS) and to evaluate quantitative ultrasonography (US) as a tool for diagnosis and treatment of patients ..
  41. doi Sympathetic sweat responses and skin vasomotor reflexes in carpal tunnel syndrome
    Satoshi Kuwabara
    Department of Neurology, Chiba University School of Medicine, Chiba, Japan
    Clin Neurol Neurosurg 110:691-5. 2008
    To investigate cutaneous sympathetic functions in carpal tunnel syndrome (CTS) using sympathetic sweat responses (SSwRs) and skin vasomotor reflexes (SVmRs).
  42. doi Bilateral widespread mechanical pain sensitivity in carpal tunnel syndrome: evidence of central processing in unilateral neuropathy
    César Fernández-de-Las-Peñas
    Facultad de Ciencias de la Salud, Universidad Rey Juan Carlos, Avenida de Atenas s n, Alcorcon, Madrid, Spain
    Brain 132:1472-9. 2009
    ..to investigate whether bilateral widespread pressure hypersensitivity exists in patients with unilateral carpal tunnel syndrome. A total of 20 females with carpal tunnel syndrome (aged 22-60 years), and 20 healthy matched females (..
  43. doi Questionnaire tools for the diagnosis of carpal tunnel syndrome from the patient history
    Jeremy D P Bland
    EEG Department, NHS Trust East Kent Hospitals University, Ethelbert Road, Canterbury, Kent CT1 3NG, UK
    Muscle Nerve 44:757-62. 2011
    There remains no "gold standard" for the diagnosis of carpal tunnel syndrome (CTS). Clinical diagnosis is often held to be paramount but depends on the skills of the individual practitioner...
  44. ncbi Histology of the transverse carpal ligament and flexor tenosynovium in idiopathic carpal tunnel syndrome
    K Nakamichi
    Department of Orthopaedic Surgery, Toranomon Hospital, Tokyo, Japan
    J Hand Surg Am 23:1015-24. 1998
    ..carpal ligament and flexor tenosynovium was investigated in 166 wrists from 130 patients with idiopathic carpal tunnel syndrome. Nine wrists from 9 controls were used for comparison. In the patients, 73.5% of the ligament and 56...
  45. pmc Carpal tunnel syndrome and peripheral polyneuropathy in patients with end stage kidney disease
    Hee Kyu Kwon
    Department of Physical Medicine and Rehabilitation, Korea University College of Medicine, Seoul, Korea
    J Korean Med Sci 26:1227-30. 2011
    This study was designed to identify the causes of the development of carpal tunnel syndrome (CTS) associated with end stage kidney disease (ESKD)...
  46. doi Changes in tissue substance P levels in patients with carpal tunnel syndrome
    Niyazi Öztürk
    1Department of Orthopedics and Traumatology, School of Medicine, Akdeniz University, Antalya, Turkey 2Department of Medical Pharmacology, School of Medicine, Akdeniz University, Antalya, Turkey
    Neurosurgery 67:1655-60; discussion 1660-1. 2010
    Although carpal tunnel syndrome (CTS) is the most common entrapment neuropathy in adults, its etiology is not completely known...
  47. pmc Is surgical intervention more effective than non-surgical treatment for carpal tunnel syndrome? A systematic review
    Qiyun Shi
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, L8S 4L8, Canada
    J Orthop Surg Res 6:17. 2011
    b>Carpal tunnel syndrome is a common disorder in hand surgery practice. Both surgical and conservative interventions are utilized for the carpal tunnel syndrome...
  48. ncbi Dupuytren's disease, carpal tunnel syndrome, trigger finger, and diabetes mellitus
    M Chammas
    Department of Endocrinology, Lapeyronie University Hospital, Montpellier, France
    J Hand Surg Am 20:109-14. 1995
    ..adults as controls showed significantly higher incidence of Dupuytren's disease, limited joint motion, carpal tunnel syndrome, and flexor tenosynovitis in the diabetic population...
  49. doi High prevalence of wild-type transthyretin deposition in patients with idiopathic carpal tunnel syndrome: a common cause of carpal tunnel syndrome in the elderly
    Yoshiki Sekijima
    Department of Medicine Neurology and Rheumatology, Shinshu University School of Medicine, Matsumoto 390 8621, Japan
    Hum Pathol 42:1785-91. 2011
    b>Carpal tunnel syndrome is the most common type of entrapment neuropathy. However, the cause of carpal tunnel syndrome remains unclear in most cases...
  50. doi Carpal tunnel syndrome and its relationship to occupation: a meta-analysis
    Annica Barcenilla
    Department of Rheumatology, Institute of Bone and Joint Research, University of Sydney, Level 4, Building 35, Royal North Shore Hospital, St Leonards, NSW 2065, Australia
    Rheumatology (Oxford) 51:250-61. 2012
    ..To examine the association between work place exposure and CTS by meta-analysis, including analyses with respect to exposure to hand force, repetition, vibration and wrist posture...
  51. pmc Carpal tunnel syndrome in hemodialysis patients as a dialysis-related amyloidosis manifestation--incidence, risk factors and results of surgical treatment
    Jerzy Kopeć
    Department of Nephrology, Jagiellonian University, Collegium Medicum, Cracow, Poland
    Med Sci Monit 17:CR505-9. 2011
    b>Carpal tunnel syndrome (CTS) is the most common complication of dialysis-related amyloidosis (DRA) developing in patients on long-term dialysis therapy...
  52. ncbi Relationship between the self-administered Boston questionnaire and electrophysiological findings in follow-up of surgically-treated carpal tunnel syndrome
    M Mondelli
    Unit of Neurosurgery, Azienda Ospedialiera Senese and Department of Neurology, Catholic University, Rome, Italy
    J Hand Surg Br 25:128-34. 2000
    ..and the Boston self-administered questionnaire (BQ) was carried out in patients with surgically-treated carpal tunnel syndrome. There were 104 hands in 93 patients (13 men and 80 women, mean age 56 years)...
  53. doi Carpal tunnel syndrome in manual wheelchair users with spinal cord injury: a cross-sectional multicenter study
    Jennifer Yang
    Human Engineering Research Laboratories, Department of Physical Medicine and Rehabilitation, School of Medicine, University of Pittsburgh, Pittsburgh, PA 15206, USA
    Am J Phys Med Rehabil 88:1007-16. 2009
    To investigate relationships between carpal tunnel syndrome, functional status, subject demographics, physical examination findings, and median nerve conduction study findings in manual wheelchair users with paraplegia.
  54. pmc Differences in risk factors for neurophysiologically confirmed carpal tunnel syndrome and illness with similar symptoms but normal median nerve function: a case-control study
    David Coggon
    MRC Lifecourse Epidemiology Unit, University of Southampton, Southampton SO16 6YD, UK
    BMC Musculoskelet Disord 14:240. 2013
    To explore whether risk factors for neurophysiologically confirmed carpal tunnel syndrome (CTS) differ from those for sensory symptoms with normal median nerve conduction, and to test the validity and practical utility of a proposed ..
  55. doi Medical and non-medical correlates of carpal tunnel syndrome in a Taiwan cohort of one million
    C H Tseng
    Department of Neurology, China Medical University Hospital, Taichung, Taiwan
    Eur J Neurol 19:91-7. 2012
    b>Carpal tunnel syndrome (CTS), with unclear etiology, is the most common entrapment neuropathy. Its occurrence is related to lots of medical and non-medical conditions with uncertain causality...
  56. doi Electrodiagnostic evaluation of carpal tunnel syndrome
    Robert A Werner
    University of Michigan Health System, Ann Arbor Veterans Health System, Ann Arbor, Michigan, USA
    Muscle Nerve 44:597-607. 2011
    b>Carpal tunnel syndrome (CTS) is the most common nerve entrapment. Electrodiagnostic (EDX) studies are a valid and reliable means of confirming the diagnosis...
  57. ncbi Nerves in a pinch: imaging of nerve compression syndromes
    Mary G Hochman
    Department of Musculoskeletal Radiology, Beth Israel Deaconess Medical Center and Harvard Medical School, 330 Brookline Avenue, Boston, MA 02215, USA
    Radiol Clin North Am 42:221-45. 2004
    ....
  58. doi Impact of compensation on work outcome of carpal tunnel syndrome
    Paul Sperka
    Community and Occupational Medicine Program, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada
    Occup Med (Lond) 58:490-5. 2008
    Work-related carpal tunnel syndrome (CTS) is a complex and costly condition. There is some evidence that the employment outcome may be worse in cases of CTS where the condition is being considered for compensation.
  59. pmc Effects of carpal tunnel syndrome on adaptation of multi-digit forces to object weight for whole-hand manipulation
    Wei Zhang
    School of Biological and Health Systems Engineering, Arizona State University, Tempe, Arizona, United States of America
    PLoS ONE 6:e27715. 2011
    ..One such condition is Carpal Tunnel Syndrome (CTS), a compression neuropathy of the median nerve that causes sensory and motor deficits in a subset of ..
  60. ncbi Best diagnostic criterion in high-resolution ultrasonography for carpal tunnel syndrome
    Lin Yi Wang
    Department of Rehabilitation, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Chang Gung Med J 31:469-76. 2008
    High-resolution ultrasonography (HRUS) has been used to diagnose carpal tunnel syndrome (CTS) in recent years. However, the best diagnostic criterion and optimal cut-off value for HRUS remain controversial.
  61. doi Pressure pain sensitivity topographical maps reveal bilateral hyperalgesia of the hands in patients with unilateral carpal tunnel syndrome
    César Fernández-de-Las-Peñas
    Universidad Rey Juan Carlos, Alcorcon, Madrid, Spain
    Arthritis Care Res (Hoboken) 62:1055-64. 2010
    To assess topographical pressure pain sensitivity maps of the hand in patients with unilateral carpal tunnel syndrome (CTS) as compared with healthy subjects.
  62. doi Carpal tunnel syndrome associated with the use of aromatase inhibitors in breast cancer
    Taiga Nishihori
    Department of Internal Medicine, Medical Oncology, Yale University School of Medicine, Yale Comprehensive Cancer Center, New Haven, CT, USA
    Clin Breast Cancer 8:362-5. 2008
    ..Joint-related symptoms, however, are seen in a significant proportion of patients. Carpal tunnel syndrome (CTS) is a common nerve entrapment disorder affecting the median nerve...
  63. ncbi Carpal tunnel syndrome pain treated with low-level laser and microamperes transcutaneous electric nerve stimulation: A controlled study
    Margaret A Naeser
    Department of Neurology, Boston University School of Medicine, Psychology Research Service, MA, USA
    Arch Phys Med Rehabil 83:978-88. 2002
    To investigate whether real or sham low-level laser therapy (LLLT) plus microamperes transcutaneous electric nerve stimulation (TENS) applied to acupuncture points significantly reduces pain in carpal tunnel syndrome (CTS).
  64. ncbi The relationship between electrodiagnostic severity and Washington Neuropathic Pain Scale in patients with carpal tunnel syndrome
    Cagatay Oncel
    Department of Neurology, Pamukkale University, Faculty of Medicine, Denizli, Turkey
    Agri 21:146-8. 2009
    We undertook this study to examine the relationships between clinical symptoms as evaluated by Washington Neuropathic Pain Scale (NPS) and electrodiagnostic classification in patients with carpal tunnel syndrome (CTS).
  65. doi The ultrasonographic wrist-to-forearm median nerve area ratio in carpal tunnel syndrome
    Lisa D Hobson-Webb
    Department of Medicine Division of Neurology, Duke University Medical Center, P O Box 3403, Clinic IL, Duke South Trent Drive, Durham, NC 27710, USA
    Clin Neurophysiol 119:1353-7. 2008
    Peripheral nerve ultrasound is an emerging tool in the diagnosis of carpal tunnel syndrome (CTS)...
  66. ncbi Changes in the functional structure of the tenosynovium in idiopathic carpal tunnel syndrome: a scanning electron microscope study
    Anke M Ettema
    Biomechanics Laboratory, Division of Orthopedic Research, Mayo Clinic College of Medicine, Rochester, Minn 55902, USA
    Plast Reconstr Surg 118:1413-22. 2006
    ..Although tenosynovial fibrosis is nearly universally noted in patients with carpal tunnel syndrome, the relationship, if any, between the fibrosis and nerve abnormalities is unknown...
  67. ncbi Prevalence of carpal tunnel syndrome in meat and fish processing plants
    Joon Youn Kim
    Department of Preventive Medicine, College of Medicine, Dong A University, Busan, Korea
    J Occup Health 46:230-4. 2004
    This study was carried out to survey the prevalence of carpal tunnel syndrome (CTS) in a high-risk job...
  68. doi Bilateral hand/wrist heat and cold hyperalgesia, but not hypoesthesia, in unilateral carpal tunnel syndrome
    Ana Isabel de la Llave-Rincón
    Department of Physical Therapy, Occupational Therapy, Rehabilitation and Physical Medicine, Facultad de Ciencias de la Salud, Universidad Rey Juan Carlos, Avenida de Atenas s n, 28922, Alcorcon, Madrid, Spain
    Exp Brain Res 198:455-63. 2009
    ..bilaterally warm/cold detection and heat/cold pain thresholds over the hand/wrist in patients with carpal tunnel syndrome (CTS)...
  69. ncbi Prevalence of musculoskeletal symptoms and carpal tunnel syndrome among dental hygienists
    Dan Anton
    Biomechanics and Ergonomics Facility, Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, Iowa 52242, USA
    Am J Ind Med 42:248-57. 2002
    b>Carpal tunnel syndrome (CTS) and other work-related musculoskeletal disorders (MSDs) are common problems in general industry as well as dental hygiene...
  70. doi Association of occupational and non-occupational risk factors with the prevalence of work related carpal tunnel syndrome
    Maryam Maghsoudipour
    University of Social Welfare and Rehabilitation, Koodakyar St, Daneshjoo Bvd, Tehran 1984738153, Iran
    J Occup Rehabil 18:152-6. 2008
    Several occupational and personal risk factors cause the development of carpal tunnel syndrome (CTS). The purpose of the study was to evaluate both non-occupational and occupational factors associated with CTS in industrial workers.
  71. doi Central sensitization in carpal tunnel syndrome with extraterritorial spread of sensory symptoms
    Giampietro Zanette
    Department of Neurological and Visual Sciences, Section of Rehabilitative Neurology, University of Verona, Verona, Italy
    Pain 148:227-36. 2010
    Extraterritorial spread of sensory symptoms is frequent in carpal tunnel syndrome (CTS). Animal models suggest that this phenomenon may depend on central sensitization...
  72. ncbi Effects of chronic median nerve compression at the wrist on sensation and manual skills
    J Thonnard
    Unite de Readaptation et de medecine physique, Universite Catholique de Louvain, 53 avenue Mounier, Tour Pasteur, B 5375 Brussels, Belgium
    Exp Brain Res 128:61-4. 1999
    ..Hand function was assessed in 11 patients (8 women and 3 men) with severe carpal tunnel syndrome (CTS) and compared with that of an age- and sex-matched control group...
  73. ncbi Prevalence of carpal tunnel syndrome and median mononeuropathy among dentists
    C Hamann
    Department of Environmental Health Sciences, School of Public Health, University of Michigan, Ann Arbor
    J Am Dent Assoc 132:163-70; quiz 223-4. 2001
    The authors undertook a study to determine the prevalence in dentists of abnormal sensory nerve conduction and/or symptoms of carpal tunnel syndrome, or CTS, the most common nerve entrapment syndrome.
  74. ncbi Outcomes of carpal tunnel release in diabetic and non-diabetic patients
    Y Ozkul
    Department of Neurology, Faculty of Medicine, University of Harran, Sanliurfa, Turkey
    Acta Neurol Scand 106:168-72. 2002
    To investigate the postoperative prognosis of carpal tunnel syndrome (CTS) in diabetic patients compared with non-diabetic patients.
  75. ncbi High resolution ultrasonography in the diagnosis of the carpal tunnel syndrome
    Elsa Iannicelli
    Dipartimento di Radiologia, II Facolta di Medicina, Roma, Italy
    Radiol Med 110:623-9. 2005
    b>Carpal tunnel syndrome (CTS) is a neuropathy caused by compression of the median nerve in the carpal tunnel...
  76. doi Differential involvement of A-delta and A-beta fibres in neuropathic pain related to carpal tunnel syndrome
    A Truini
    Department of Neurological Sciences, University La Sapienza, Rome, Italy
    Pain 145:105-9. 2009
    b>Carpal tunnel syndrome (CTS), a common entrapment neuropathy involving the median nerve at the wrist, frequently manifests with neuropathic pain. We sought information on pain mechanisms in CTS...
  77. doi Acupuncture for carpal tunnel syndrome: a systematic review of randomized controlled trials
    Hoseob Sim
    School of Korean Medicine, Pusan National University, Yangsan, South Korea
    J Pain 12:307-14. 2011
    Acupuncture is a widely used symptomatic treatment for carpal tunnel syndrome (CTS). The objective of this systematic review was to evaluate the evidence of the effectiveness of acupuncture and acupuncture-like treatments for CTS...
  78. ncbi Thickening of the synovium of the digital flexor tendons: cause or consequence of the carpal tunnel syndrome?
    A L Lluch
    Hand Unit, Hospital Sant Pau, Barcelona, Spain
    J Hand Surg Br 17:209-12. 1992
    ..As a result, the volume of the carpal tunnel was diminished, and "carpal tunnel syndrome" was produced. At various intervals after this procedure the animals were sacrificed...
  79. pmc The effect of wrist position on the relative motion of tendon, nerve, and subsynovial connective tissue within the carpal tunnel in a human cadaver model
    Yuichi Yoshii
    Biomechanics Laboratory, Division of Orthopedic Research, Mayo Clinic, 200 First Street SW, Rochester, Minnesota 55905, USA
    J Orthop Res 26:1153-8. 2008
    ..Thus, this result suggests that the SSCT may be predisposed to shear injury from activity done in 60 degrees of wrist flexion...
  80. doi Clinical diagnosis of carpal tunnel syndrome: old tests-new concepts
    Yasser El Miedany
    Rheumatology and Rehabilitation, Ain Shams University, Cairo, Egypt
    Joint Bone Spine 75:451-7. 2008
    The diagnosis of carpal tunnel syndrome (CTS) continues to be neurophysiologically and clinically controversial...
  81. ncbi Postoperative morphologic analysis of carpal tunnel syndrome using high-resolution ultrasonography
    Chi Ho Lee
    Department of Plastic and Reconstructive Surgery, Korea University, Ansan Hospital, Ansan, Korea
    Ann Plast Surg 54:143-6. 2005
    ..evaluated the morphologic changes that follow division of the transverse carpal ligament in patients with carpal tunnel syndrome (CTS) using high-resolution ultrasonography...
  82. ncbi Comparison of open carpal tunnel release and local steroid treatment outcomes in idiopathic carpal tunnel syndrome
    Serpil Demirci
    Department of Neurology, Suleyman Demirel University School of Medicine, Isparta, Turkey
    Rheumatol Int 22:33-7. 2002
    ..motor nerve conduction studies were performed in 90 patients with electrophysiologically proven idiopathic carpal tunnel syndrome, of whom 44 were treated surgically and 46 by two-dose steroid injection...
  83. ncbi Ultrasonography in carpal tunnel syndrome: comparison with electrophysiological stage and motor unit number estimate
    Ilkay Koray Bayrak
    Department of Radiology, Ondokuz Mayis University School of Medicine, Kurupelit 55139, Samsun, Turkey
    Muscle Nerve 35:344-8. 2007
    ..was to document the ultrasonographic measurement differences in median nerve size between patients with carpal tunnel syndrome (CTS) and controls, and to correlate these findings with electrophysiological stage and motor unit number ..
  84. ncbi Towards development of a nonhuman primate model of carpal tunnel syndrome: performance of a voluntary, repetitive pinching task induces median mononeuropathy in Macaca fascicularis
    Carolyn M Sommerich
    Department of Industrial, Welding and Systems Engineering, The Ohio State University, 1971 Neil Avenue, Room 210, Columbus, OH 43210, USA
    J Orthop Res 25:713-24. 2007
    ..to the pattern of evidence of a causal relationship between manual work, median mononeuropathy, and carpal tunnel syndrome in humans...
  85. ncbi Hand dominance in upper extremity musculoskeletal disorders
    Rahman Shiri
    Musculoskeletal Center, Finnish Institute of Occupational Health, and Department of Health and Functional Capacity, National Public Health Institute, Helsinki, Finland
    J Rheumatol 34:1076-82. 2007
    ..To investigate the role of hand dominance in common upper extremity musculoskeletal disorders (UEMSD) in a population study...
  86. ncbi Carpal tunnel syndrome with normal nerve conduction studies
    John C Witt
    Department of Neurology, Mayo Clinic, Scottsdale, Arizona, USA
    Muscle Nerve 29:515-22. 2004
    The utility of electrodiagnostic testing in the evaluation of carpal tunnel syndrome (CTS) has been questioned...
  87. ncbi Ultrasonography shows increased cross-sectional area of the median nerve in patients with arthritis and carpal tunnel syndrome
    H B Hammer
    Department of Rheumatology, Diakonhjemmet Hospital, Box 23, Vinderen, N 0319 Oslo, Norway
    Rheumatology (Oxford) 45:584-8. 2006
    To examine whether patients with arthritic diseases and carpal tunnel syndrome (CTS) have increased cross-sectional areas of the median nerves measured by ultrasonography (US)...
  88. ncbi High-resolution sonography versus EMG in the diagnosis of carpal tunnel syndrome
    L H Visser
    Department of Neurology, St Elisabeth Hospital, PO Box 90151, 5000 LC Tilburg, The Netherlands
    J Neurol Neurosurg Psychiatry 79:63-7. 2008
    b>Carpal tunnel syndrome (CTS) is a common entrapment neuropathy. Electrodiagnostic testing (EMG) is used to confirm the diagnosis. It is not known what the diagnostic accuracy of high-resolution sonography is in comparison to EMG.
  89. doi Carpal tunnel syndrome: ultrasound, neurophysiology, clinical and patient-oriented assessment
    L Padua
    Institute of Neurology, Universita Cattolica del Sacro Cuore, Largo F Vito 1, 00168 Rome, Italy
    Clin Neurophysiol 119:2064-9. 2008
    ..Second, to assess the sensitivity of ultrasonography (US) and neurophysiology in the diagnosis of CTS using clinical measures as gold standard...
  90. ncbi Biochemistry of carpal tunnel syndrome
    Vipul Sud
    Division of Plastic Surgery, Department of Surgery, Batra Hospital and Research Centre, New Delhi, India
    Microsurgery 25:44-6. 2005
    Although carpal tunnel syndrome (CTS) occurs due to intrinsic or extrinsic causes, the idiopathic group outnumbers the rest by far. Compression of the median nerve may be due to mechanical or ischemic causation...
  91. pmc Nonoccupational risk factors for carpal tunnel syndrome
    D H Solomon
    Division of Pharmacoepidemiology and Pharmacoeconomics, Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. 02115, USA
    J Gen Intern Med 14:310-4. 1999
    OBJECTIVE: To examine the relation between selected nonoccupational risk factors and surgery for carpal tunnel syndrome. DESIGN: Case-control study using an administrative database...
  92. ncbi Surgical treatment of carpal tunnel syndrome and trigger digits in children with mucopolysaccharide storage disorders
    A E Van Heest
    Department of Orthopaedic Surgery, University of Minnesota, Minneapolis 55455, USA
    J Hand Surg Am 23:236-43. 1998
    The role of surgical intervention for carpal tunnel syndrome (CTS) and trigger digits in children with mucopolysaccharide storage disorders (MPSDs) has not been clearly defined, particularly as the treatment of the underlying disease has ..
  93. ncbi Somatosensory cortical plasticity in carpal tunnel syndrome--a cross-sectional fMRI evaluation
    Vitaly Napadow
    Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA
    Neuroimage 31:520-30. 2006
    b>Carpal tunnel syndrome (CTS) is a common entrapment neuropathy of the median nerve characterized by paresthesias and pain in the first, second, and third digits...
  94. ncbi Splinting vs surgery in the treatment of carpal tunnel syndrome: a randomized controlled trial
    Annette A M Gerritsen
    Institute for Research in Extramural Medicine, Vrije Universiteit Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    JAMA 288:1245-51. 2002
    b>Carpal tunnel syndrome (CTS) can be treated with nonsurgical or surgical options. However, there is no consensus on the most effective method of treatment.
  95. ncbi Conservative treatment options for carpal tunnel syndrome: a systematic review of randomised controlled trials
    Annette A M Gerritsen
    Institute for Research in Extramural Medicine, Vrije Universiteit Medical Centre, Amsterdam, The Netherlands
    J Neurol 249:272-80. 2002
    b>Carpal tunnel syndrome (CTS) is a common disorder, for which various conservative treatment options are available...
  96. ncbi Carpal tunnel syndrome: diagnostic usefulness of sonography
    Shiu Man Wong
    Department of Medicine, Prince of Wales Hospital, Shatin, Hong Kong
    Radiology 232:93-9. 2004
    To prospectively evaluate accuracy of sonography for diagnosis of carpal tunnel syndrome (CTS) in patients clinically suspected of having the disease in one or both hands.
  97. doi Diagnostic utility of ultrasonography versus nerve conduction studies in mild carpal tunnel syndrome
    Mauro Mondelli
    EMG Service ASL 7, Siena, Italy
    Arthritis Rheum 59:357-66. 2008
    To prospectively compare high-resolution ultrasonography (US) and nerve conduction velocity (NCV) in clinically diagnosed mild carpal tunnel syndrome (CTS).
  98. doi Effects of traditional cupping therapy in patients with carpal tunnel syndrome: a randomized controlled trial
    Andreas Michalsen
    Immanuel Hospital Berlin, Department of Internal and Complementary Medicine, Berlin, Germany
    J Pain 10:601-8. 2009
    ..the effectiveness of cupping, a traditional method of treating musculoskeletal pain, in patients with carpal tunnel syndrome (CTS) in an open randomized trial. n = 52 outpatients (58.5 +/- 8...
  99. pmc Carpal tunnel syndrome
    Jeremy D P Bland
    Kent and Canterbury Hospital, Canterbury CT1 3NG
    BMJ 335:343-6. 2007
  100. ncbi A randomized controlled trial of surgery vs steroid injection for carpal tunnel syndrome
    A C F Hui
    Division of Neurology, Department of Medicine, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong, China
    Neurology 64:2074-8. 2005
    Decompressive surgery and steroid injection are widely used forms of treatment for carpal tunnel syndrome (CTS) but there is no consensus on their effectiveness in comparison to each other...
  101. ncbi Clinical features of 1039 patients with neurophysiological diagnosis of carpal tunnel syndrome
    Daniel B Nora
    Porto Alegre Research Group in Neuromuscular Diseases PARG, Porto Alegre, Brazil
    Clin Neurol Neurosurg 107:64-9. 2004
    To describe the clinical features of patients with a neurophysiologic diagnosis of carpal tunnel syndrome (CTS) in the state of Rio Grande do Sul, Brazil.

Research Grants64

  1. Sex Differences in Musculoskeletal Conditions across the Lifespan
    Nancy E Lane; Fiscal Year: 2013
    ..clinical study of sex differences in high resolution ultrasound in diagnosis and prognosis of carpal tunnel syndrome with conservative and surgical treatment, and a randomized trial of sex differences in response to a ..
  2. A New Device for Rapid Measurement of Touch Sensation in neuropathy
    Donald A Simone; Fiscal Year: 2010
    ..is a disabling complication of many conditions including diabetes, alcohol abuse, HIV infection, carpal tunnel syndrome, and chemotherapy for cancer...
  3. Schwann Cell Control of Chronic Nerve Injury
    Ranjan Gupta; Fiscal Year: 2013
    ..applicant): Each year, millions of Americans suffer from chronic nerve compression (CNC) injuries such as carpal tunnel syndrome, cubital tunnel syndrome, and spinal nerve root stenosis...
  4. Hand Sensorimotor Function and Carpal Tunnel Syndrome
    Zong Ming Li; Fiscal Year: 2013
    ..provided by applicant): The median nerve is susceptible to compression in the wrist, leading to carpal tunnel syndrome (CTS)...
  5. Noninvasive Assessment of Neuromuscular Disease using Electrical Impedance
    Jeremy M Shefner; Fiscal Year: 2013
    ..disorders include a wide group of conditions ranging from relatively mild focal problems, such as carpal tunnel syndrome, to severe, generalized diseases, such as amyotrophic lateral sclerosis (ALS)...
  6. A Pooled Longitudinal Analysis of Workplace Carpal Tunnel Syndrome
    David M Rempel; Fiscal Year: 2012
    A Pooled Longitudinal Analysis of Workplace Carpal Tunnel Syndrome Carpal tunnel syndrome continues to be a major source of disability among working persons and a major expense to employers and insurers...
  7. Exposure Response Relationships for CTS and Epicondylitis from Pooled Data
    Arun Garg; Fiscal Year: 2013
    ..non-occupational physical activities, demographics, medical history, psychosocial factors;and risk of carpal tunnel syndrome (CTS), lateral epicondylitis (LEPI), and medial epicondylitis (MEPI)...
  8. Development of an Alternative Manual Drive System for Wheelchair Mobility
    Michael Bayne; Fiscal Year: 2012
    ..Between 49% to 73% of full time MWC users report carpal tunnel syndrome (CTS) symptoms and 31% to 73% report shoulder pain...
  9. Brain Plasticity in Carpal Tunnel Syndrome and its Response to Acupuncture
    Vitaly Napadow; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Carpal tunnel syndrome (CTS), the most common entrapment neuropathy, is exceeded only by low back pain as a cause of employee absenteeism...
  10. An Outcome Study for Ulnar Neuropathy at the Elbow
    JAE WON SONG; Fiscal Year: 2011
    ..In contrast, a great deal of information has been collected for outcomes following carpal tunnel syndrome, which is highly dependent on patient-rated questionnaires...
  11. Local Biomechanics of Median Nerve Insult in Carpal Tunnel Syndrome
    THOMAS DUDLEY BROWN; Fiscal Year: 2010
    b>Carpal tunnel syndrome (CTS) is among the most important of the family of musculoskeletal disorders caused by chronic peripheral nerve compression...
  12. Post-offer screening and risk factors for CTS
    Bradley Evanoff; Fiscal Year: 2013
    ..provided by applicant): The overall aim of this study is to better understand important aspects of Carpal Tunnel Syndrome (CTS), a common disabling condition affecting working populations. The study consists of four major aims...
  13. Sensorimotor integration underlying hand control in Carpal Tunnel Syndrome
    Marco Santello; Fiscal Year: 2012
    ..to object properties can be disrupted by a number of neurological and musculo-skeletal diseases such as Carpal Tunnel Syndrome (CTS)...
  14. Dynamic Ultrasound Measurement of Median Nerve Kinematics in the Carpal Tunnel
    Jessica E Goetz; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Carpal tunnel syndrome (CTS) is the most commonly encountered compressive peripheral neuropathy, and the economic burden associated with its diagnosis, treatment, and indirect costs is in the billions ..
  15. Macaque Model of Carpal Tunnel Syndrome: Effects of Force and Posture Exposures
    Carolyn M Sommerich; Fiscal Year: 2010
    ..provided by applicant): The long term objective of this research is to reduce occurrence of work-related Carpal Tunnel Syndrome (CTS)...
  16. The Value of High Quality Medical Care for Work-Associated Carpal Tunnel Syndrome
    Steven M Asch; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Carpal tunnel syndrome (CTS) commonly affects working-age adults, causes severe functional impairment, and leads to both medical and disability costs...
  17. Exploration of Carpal Tunnel Mechanics for CTS Treatment
    Zong Ming Li; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Carpal tunnel syndrome (CTS) is the most common compression neuropathy and has an immense impact on national health care, worker productivity, and quality of life...
  18. A LONGITUDINAL STUDY OF MUSKULOSKELETAL DISORDERS
    Laura Punnett; Fiscal Year: 1990
    ..the results of two-point discrimination testing for median nerve impairment and other indications of carpal tunnel syndrome; (6) to explore the association between upper extremity pain and work pace under a piece-rate wage system; ..
  19. An Improved Lever Drive Wheelchair Transmission
    Steve Green; Fiscal Year: 2001
    ..The most common are shoulder injuries and carpal tunnel syndrome (CTS)...
  20. An Improved Lever Drive Wheelchair Transmission
    Steve Green; Fiscal Year: 2003
    ..Surveys of manual wheelchair users show the prevalence of shoulder pain to be between 31 and 73% and of Carpal Tunnel Syndrome to be between 49 and 73%...
  21. Wrist Flexion to Identify Carpal Tunnel Syndrome
    ROBERT TUCKETT; Fiscal Year: 2001
    DESCRIPTION (Applicant's Abstract): Although most health care practitioners would define carpal tunnel syndrome (CTS) as an entrapment, or compression, of the median nerve at the level of the wrist (e.g...
  22. Costs of Occupational Injury and Illness
    J Leigh; Fiscal Year: 2009
    ..cancer, lung cancer, coronary heart disease, and renal disease;4) non-fatal diseases such as dermatitis, carpal tunnel syndrome, hernia, and poisoning;5) fatal injuries such as homicides and falls;6) and non-fatal injuries such as ..
  23. OCCUPATIONAL EPIDEMIOLOGY OF CARPAL TUNNEL SYNDROME
    Hal Morgenstern; Fiscal Year: 1991
    ..b>Carpal tunnel syndrome (CTS) is one of the most commonly reported and widespread of the cumulative trauma disorders...
  24. AN INVESTIGATION OF OCCUPATIONAL WRIST INJURIES IN WOMEN
    Don Chaffin; Fiscal Year: 1980
    ..3 cases of carpal tunnel syndrome occurred per million man hours worked...
  25. Core Surveillance Model Program in California
    Robert Harrison; Fiscal Year: 2003
    ..and investigation of multiple work-related diseases and injuries, including asthma, pesticide illness, carpal tunnel syndrome, selected fatal injuries and lead poisoning...
  26. OCCUPATIONAL HEALTH GRADIENTS IN HOSPITAL WORKERS: THE
    Paul Blanc; Fiscal Year: 2004
    ..a broad class of outcomes including low back pain and upper extremity injuries, such as tendinitis and carpal tunnel syndrome. Both psychosocial and physical-ergonomic exposures at work are now thought to be joint determinants of ..
  27. A Modal Reciprocating Pushrim Drive Wheelchair
    Steve Green; Fiscal Year: 2003
    ..users surveyed, prevalence of shoulder pain is seen to be between 31 percent and 73 percent, and carpal tunnel syndrome (CTS) to be between 49 percent and 73 percent...
  28. NIAMS Muiltidisciplinary Clinical Research Center in...
    Richard Deyo; Fiscal Year: 2006
    ..These conditions, especially low back pain and carpal tunnel syndrome, are among the most common and disabling conditions in working age populations...
  29. TRIAL OF ACUPUNCTURE FOR CARPAL TUNNEL SYNDROME
    Arthur Weinstein; Fiscal Year: 2001
    ..The condition to be studied is carpal tunnel syndrome (CTS), a common, well delineated syndrome causing hand pain with characteristic clinical and objective ..
  30. EXPERIMENTAL INDUCTION OF CARPAL TUNNEL SYNDROME
    Edward Diao; Fiscal Year: 2004
    DESCRIPTION: Carpal Tunnel Syndrome (CTS) is a common clinical problem that has assumed epidemic proportions and is dramatically increasing in the working population...
  31. QUANTITATIVE MEASURES OF WRIST MOTIONS
    William Marras; Fiscal Year: 1990
    ..growing occupationally related problems in industry is that of hand and wrist cumulative trauma disorders (Carpal tunnel syndrome, tenosynovitis, etc.)...
  32. WHEELCHAIR PROPULSION BIOMECHANICS AND ARM PAIN
    Michael Boninger; Fiscal Year: 1999
    ..users (MWUs) with spinal cord injuries (SCI) is between 30% and 70% and mononeuropathies such as carpal tunnel syndrome have a prevalence between 40% and 60%...
  33. PREVENTION--UPPER EXTREMITY CUMULATIVE TRAUMA DISORDERS
    Patricia Gucer; Fiscal Year: 2001
    ..Bureau of Labor Statistics (BLS) 1995 Report on Lost- Workday Injuries showed that employees disabled by carpal tunnel syndrome experienced the largest median lost-work day rate among disabling conditions...
  34. SHAM DEVICE, PILL PLACEBO OR TREATMENT FOR ARM PAIN
    Ted Kaptchuk; Fiscal Year: 2003
    ..in patients with persistent upper extremity pain secondary to repetitive strain injury (RSI) most notably, carpal tunnel syndrome (CTS)...
  35. A Modal Reciprocating Pushrim Drive Wheelchair
    Steve Green; Fiscal Year: 2006
    ..Among manual wheelchair users surveyed, prevalence of shoulder pain is seen to be between 31% and 73%, and carpal tunnel syndrome (CTS) to be between 49% and 73%...
  36. QUANTITATIVE ASSESSMENT OF CARPAL TUNNEL SYNDROME
    Fredric Gerr; Fiscal Year: 1992
    ..b>Carpal tunnel syndrome is often considered prototypic of these disorders...
  37. ROCHESTER NEUROEPIDEMIOLOGY PROGRAM PROJECT
    LEONARD KURLAND; Fiscal Year: 1991
    ..Case-control studies of carpal tunnel syndrome, Bell's palsy, cerebral palsy, mental retardation, brain tumors, and anorexia nervosa are proposed...
  38. Biomechanical Evaluation of Wrist Ligament Injuries
    WALTER SHORT; Fiscal Year: 2005
    ..The diagnosis of wrist ligament injuries increases yearly and they are now as common as carpal tunnel syndrome. At our present knowledge of the pathomechanics, early diagnosis and treatment are limited and ..
  39. AXONAL TRANSPORT AND PERIPHERAL NERVE FUNCTION
    Kimberly Topp; Fiscal Year: 2001
    ..needs medical attention for some form of neuropathy, such as low back pain, diabetic neuropathy or carpal tunnel syndrome. Due to their prevalence and complexity of treatment, neuropathies have a major financial impact in health ..
  40. Surveillance of Work-Related Carpal Tunnel Syndrome
    Robert Harrison; Fiscal Year: 2002
    ..to further develop and enhance its surveillance system for the detection and prevention of occupational carpal tunnel syndrome (CTS)...
  41. Biomechanical Properties of the Transverse Carpal Ligament
    Zong Ming Li; Fiscal Year: 2009
    b>Carpal tunnel syndrome (CTS) is the most prominent hand disorder and has an immense negative impact on national health care cost, worker productivity, and activities of daily living...
  42. Outcomes of Injured Employee Health Status Assessment
    Robert Ross; Fiscal Year: 2001
    ..including strain/sprain, cumulative trauma (upper extremity, lower extremity, lower back), tendinitis, and carpal tunnel syndrome. The study tests the utility of the WBOAS, the significance of which for workplace health improvement is ..
  43. Disability Risk in Work-Related Musculoskeletal Injury
    Gary Franklin; Fiscal Year: 2005
    ..is a 5-year, population-based, prospective study among Washington State workers with back injuries and carpal tunnel syndrome (CTS)...
  44. Shock Absorbing Brace for Study of Upper Extremity MSD's
    MICHAEL POTTENGER; Fiscal Year: 2002
    ..and arm, and is a causal factor in the development of various musculoskeletal disorders (MSD's) such as carpal tunnel syndrome (CTS) and hand-arm vibration syndrome (HAVS)...
  45. MAGNETIC MEASUREMENTS OF PERIPHERAL NERVE FUNCTION III
    John Wikswo; Fiscal Year: 1993
    ..nerve injury to determine means of prevention; assessing the effect of nerve compression in carpal tunnel syndrome, and aiding surgeons' selection of strategies to optimize repair of neuroma-in-continuity...
  46. WORKER MONITORING TESTS FOR CARPAL TUNNEL SYNDROME
    Robert Radwin; Fiscal Year: 2000
    ..tests for periodically monitoring industrial workers for subtle functional deficits associated with carpal tunnel syndrome (CTS)...
  47. CARPAL TUNNEL SYNDROME AMONG CONSTRUCTION WORKERS
    John Rosecrance; Fiscal Year: 2001
    ..The applicant proposes a cross-sectional study to characterize the prevalence of carpal tunnel syndrome (CTS) among construction apprentices...
  48. SOFTWARE FOR EARLY DETECTION OF CARPAL TUNNEL SYNDROME
    John Engel; Fiscal Year: 1993
    The goal of this project is to develop a software product which can indicate the onset of carpal tunnel syndrome (CTS) in computer keyboard operators...
  49. Mechanisms of Neural Mobilization for Chronic Pain
    STEVEN GEORGE; Fiscal Year: 2007
    ..b>Carpal tunnel syndrome (CTS) is a commonly occurring example of upper extremity chronic pain that causes disability...
  50. Characterization of Tendon Damage Accumulation
    Vincent Wang; Fiscal Year: 2004
    Tendon injuries such as those of repetitive overuse and cumulative trauma (e.g., carpal tunnel syndrome) are a major source of pain and disability, yet the mechanism of low-level injury and progression of tendon pathology is unknown...
  51. FULL CIRCLE ERGONOMIC AUXILIARY TOOL HANDLE
    Samuel Johnson; Fiscal Year: 1991
    ..It may prevent disorders such as carpal tunnel syndrome, and it may allow patients with disorders, such as arthritis or diminished grip, to use tools more ..
  52. Prevention of MSDs in Plant Nursery Work
    John Miles; Fiscal Year: 2003
    ..This is a sub population of farmworkers who have documented history of diagnosed MSDs (specifically Carpal Tunnel Syndrome)...
  53. System for Non-Invasive EMG Motor Unit Recording
    KENNETH GUILLORY; Fiscal Year: 2005
    ..will enable new remote monitoring and telehealth diagnostic capabilities for common diseases such as Carpal Tunnel Syndrome and diabetic neuropathy...
  54. PERIPHERAL NEUROPATHY, SENSORIMOTOR FUNCTIONS & BALANCE
    James Richardson; Fiscal Year: 2004
    ..Stratification of the subjects in the first group by the presence of carpal tunnel syndrome and testing the subjects in the second group at 3 and 12 weeks may give insight into the mechanisms ..
  55. CUTANEOUS MECHANORECEPTOR SYSTEMS
    STANLEY BOLANOWSKI; Fiscal Year: 1993
    ..of stimulation; 4) cross-modality interactions; and; 5) effects of peripheral neuropathies associated with carpal tunnel syndrome, vibration "white finger", and diabetes...
  56. Carpal Tunnel Syndrome and Static Magnetic Field Therapy
    AGATHA COLBERT; Fiscal Year: 2008
    ..preliminary data for a R01 that will evaluate the efficacy of static magnetic field (SMF) therapy for carpal tunnel syndrome (CTS). Therapeutic magnets are a self-help modality with estimated sales of $350 million in the US in 1999...
  57. Treatment Efficacy of OMT for Carpal Tunnel Syndrome
    SCOTT STOLL; Fiscal Year: 2008
    The incidence of Carpal Tunnel Syndrome (CTS) in adults in the U.S. ranges from 15-20% depending on the study, and costs over one billion dollars annually in medical care...
  58. TRANSDUCTION OF CHRONIC NERVE INJURY BY SCHWANN CELLS
    Ranjan Gupta; Fiscal Year: 2004
    ..Successful completion of these studies will provide a greater understanding of the pathogenesis of CNI so that more effective treatment modalities may be developed. ..
  59. Rehabilitation of Spinal Cord Injury-Related Pain
    Mark Jensen; Fiscal Year: 2006
    ..abstract_text> ..
  60. The effect of alternative keyboards on discomfort and typing kinematics
    Nancy A Baker; Fiscal Year: 2010
    ..The effectiveness of alternative keyboards must be verified to ensure that they are providing interventions that will reduce musculoskeletal pain/discomfort and potentially prevent MSD-UE. ..