postoperative pain

Summary

Summary: Pain during the period after surgery.

Top Publications

  1. ncbi Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged
    Jeffrey L Apfelbaum
    Department of Anesthesia and Critical Care, The University Chicago Hospitals, Chicago, Illinois 60637, USA
    Anesth Analg 97:534-40, table of contents. 2003
  2. ncbi Persistent postsurgical pain: risk factors and prevention
    Henrik Kehlet
    Section of Surgical Pathophysiology 4074, Juliane Marie Centre, Rigshospitalet, 2100 Copenhagen, Denmark
    Lancet 367:1618-25. 2006
  3. ncbi Preoperative prediction of severe postoperative pain
    C J Kalkman
    Department of Anesthesiology, Division of Perioperative Care and Emergency Medicine, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Pain 105:415-23. 2003
  4. ncbi Chronic pain following total hip arthroplasty: a nationwide questionnaire study
    L Nikolajsen
    Department of Anesthesiology, Aarhus University Hospital, Aarhus, Denmark
    Acta Anaesthesiol Scand 50:495-500. 2006
  5. ncbi The effect of age on pain, function, and quality of life after total hip and knee arthroplasty
    C A Jones
    Department of Public Health Sciences, PT, Room 2137, Dentistry Pharmacy Bldg, University of Alberta, Edmonton, Alberta, Canada T6G 2N8
    Arch Intern Med 161:454-60. 2001
  6. ncbi Interpretation of visual analog scale ratings and change scores: a reanalysis of two clinical trials of postoperative pain
    Mark P Jensen
    Department of Rehabilitation Medicine, School of Medicine, and Multidisciplinary Pain Center, University of Washington, Seattle, WA 98195 6490, USA
    J Pain 4:407-14. 2003
  7. ncbi Prediction of postoperative pain: a systematic review of predictive experimental pain studies
    Mads U Werner
    Multidisciplinary Pain Center, Rigshospitalet, Copenhagen University Hospitals, Copenhagen, Denmark
    Anesthesiology 112:1494-502. 2010
  8. ncbi Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy
    Wen Ying Chou
    Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Taipei, Taiwan
    Anesthesiology 105:334-7. 2006
  9. ncbi Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients
    Dennis R Kerr
    Joint Orthopaedic Centre, New South Wales, Australia
    Acta Orthop 79:174-83. 2008
  10. ncbi The effect of pulpotomy using a calcium-enriched mixture cement versus one-visit root canal therapy on postoperative pain relief in irreversible pulpitis: a randomized clinical trial
    Saeed Asgary
    Iranian Center for Endodontic Research, Dental Research Center, Dental School, Shahid Beheshti Medical University, Evin, Tehran, 1983963113, Iran
    Odontology 98:126-33. 2010

Detail Information

Publications329 found, 100 shown here

  1. ncbi Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged
    Jeffrey L Apfelbaum
    Department of Anesthesia and Critical Care, The University Chicago Hospitals, Chicago, Illinois 60637, USA
    Anesth Analg 97:534-40, table of contents. 2003
    b>Postoperative pain can have a significant effect on patient recovery. An understanding of patient attitudes and concerns about postoperative pain is important for identifying ways health care professionals can improve postoperative care...
  2. ncbi Persistent postsurgical pain: risk factors and prevention
    Henrik Kehlet
    Section of Surgical Pathophysiology 4074, Juliane Marie Centre, Rigshospitalet, 2100 Copenhagen, Denmark
    Lancet 367:1618-25. 2006
    Acute postoperative pain is followed by persistent pain in 10-50% of individuals after common operations, such as groin hernia repair, breast and thoracic surgery, leg amputation, and coronary artery bypass surgery...
  3. ncbi Preoperative prediction of severe postoperative pain
    C J Kalkman
    Department of Anesthesiology, Division of Perioperative Care and Emergency Medicine, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Pain 105:415-23. 2003
    ..The outcome was the presence of severe postoperative pain (defined as Numeric Rating Scale > or =8) within the first hour postoperatively...
  4. ncbi Chronic pain following total hip arthroplasty: a nationwide questionnaire study
    L Nikolajsen
    Department of Anesthesiology, Aarhus University Hospital, Aarhus, Denmark
    Acta Anaesthesiol Scand 50:495-500. 2006
    ..Severe pre-operative pain is the primary indication for total hip arthroplasty (THA). Therefore, we examined the prevalence of chronic pain after THA in relation to pre-operative pain and early post-operative pain...
  5. ncbi The effect of age on pain, function, and quality of life after total hip and knee arthroplasty
    C A Jones
    Department of Public Health Sciences, PT, Room 2137, Dentistry Pharmacy Bldg, University of Alberta, Edmonton, Alberta, Canada T6G 2N8
    Arch Intern Med 161:454-60. 2001
    ....
  6. ncbi Interpretation of visual analog scale ratings and change scores: a reanalysis of two clinical trials of postoperative pain
    Mark P Jensen
    Department of Rehabilitation Medicine, School of Medicine, and Multidisciplinary Pain Center, University of Washington, Seattle, WA 98195 6490, USA
    J Pain 4:407-14. 2003
    ..To address these questions, we performed a reanalysis of data from 2 randomized controlled trials of postoperative pain (N = 123 and N = 125) to determine the meaning of VAS pain intensity ratings and change scores...
  7. ncbi Prediction of postoperative pain: a systematic review of predictive experimental pain studies
    Mads U Werner
    Multidisciplinary Pain Center, Rigshospitalet, Copenhagen University Hospitals, Copenhagen, Denmark
    Anesthesiology 112:1494-502. 2010
    ..have investigated the correlation between preoperative responses to experimental pain stimuli and clinical postoperative pain and demonstrates that the preoperative pain tests may predict 4-54% of the variance in postoperative pain ..
  8. ncbi Human opioid receptor A118G polymorphism affects intravenous patient-controlled analgesia morphine consumption after total abdominal hysterectomy
    Wen Ying Chou
    Department of Anesthesiology, Kaohsiung Chang Gung Memorial Hospital, Taipei, Taiwan
    Anesthesiology 105:334-7. 2006
    ..The purpose of the current study was to investigate whether this polymorphism contributes to the variability of morphine efficacy in women who undergo abdominal total hysterectomy...
  9. ncbi Local infiltration analgesia: a technique for the control of acute postoperative pain following knee and hip surgery: a case study of 325 patients
    Dennis R Kerr
    Joint Orthopaedic Centre, New South Wales, Australia
    Acta Orthop 79:174-83. 2008
    ..The technique allows virtually immediate mobilization and earlier discharge from hospital...
  10. ncbi The effect of pulpotomy using a calcium-enriched mixture cement versus one-visit root canal therapy on postoperative pain relief in irreversible pulpitis: a randomized clinical trial
    Saeed Asgary
    Iranian Center for Endodontic Research, Dental Research Center, Dental School, Shahid Beheshti Medical University, Evin, Tehran, 1983963113, Iran
    Odontology 98:126-33. 2010
    The purpose of this noninferiority trial was to compare postoperative pain relief after one-visit root canal therapy (ORCT) with a pulpotomy performed with a new endodontic calcium-enriched mixture cement (PCEM) in human permanent molars ..
  11. ncbi Preoperative anxiolytic effect of melatonin and clonidine on postoperative pain and morphine consumption in patients undergoing abdominal hysterectomy: a double-blind, randomized, placebo-controlled study
    Wolnei Caumo
    Anesthesia Service and Perioperative Medicine, Hospital de Clinicas de Porto Alegre Universidade Federal do Rio Grande do Sul, Porto Alegre, Brazil
    J Pain 10:100-8. 2009
    ..Taking into account that higher anxiety makes the control of postoperative pain more difficult, one can hypothesize that melatonin anxiolytic and analgesic effects improve the control of ..
  12. ncbi Spinal NK-1 receptor-expressing neurons and descending pathways support fentanyl-induced pain hypersensitivity in a rat model of postoperative pain
    Cyril Rivat
    Department of Anesthesiology, College of Medicine, University of Arizona, Tucson, AZ, USA
    Eur J Neurosci 29:727-37. 2009
    ....
  13. ncbi Correlation of postoperative pain to quality of recovery in the immediate postoperative period
    Christopher L Wu
    Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21287, USA
    Reg Anesth Pain Med 30:516-22. 2005
    It is unclear whether the severity of postoperative pain may affect patients' quality of recovery in the immediate postoperative period (within 2 weeks of surgery).
  14. ncbi Prevalence and predictors of postoperative pain after ear, nose, and throat surgery
    Michael Sommer
    University Hospital Maastricht, Department of Anesthesiology and Pain Treatment, PO Box 5800, 6202 AZ Maastricht, The Netherlands
    Arch Otolaryngol Head Neck Surg 135:124-30. 2009
    To determine postoperative pain in different types of ear, nose, and throat (ENT) surgery and their psychological preoperative predictors.
  15. ncbi Relationships between surgical difficulty and postoperative pain in lower third molar extractions
    Lucía Lago-Méndez
    Postgraduate Student, Oral Surgery and Oral Medicine Unit, School of Dentistry, University of Santiago de Compostela, Santiago de Compostela, Spain
    J Oral Maxillofac Surg 65:979-83. 2007
    To investigate the influence of surgical difficulty on postoperative pain after extraction of mandibular third molars.
  16. ncbi Monoamine-dependent, opioid-independent antihypersensitivity effects of intrathecally administered milnacipran, a serotonin noradrenaline reuptake inhibitor, in a postoperative pain model in rats
    Hideaki Obata
    Department of Anesthesiology, Gunma University Graduate School of Medicine, 3 39 22 Showa, Maebashi, Gunma 371 8511, Japan
    J Pharmacol Exp Ther 334:1059-65. 2010
    ..effects of milnacipran, a 5-HT and NA reuptake inhibitor (SNRI), in the spinal cord in a rat model of postoperative pain. Sprague-Dawley rats were used in all experiments...
  17. ncbi The role of catastrophizing in the prediction of postoperative pain
    Marianna Papaioannou
    Department of Anesthesiology, General Hospital of Nikaia, Athens, Greece
    Pain Med 10:1452-9. 2009
    ..The present study aimed at investigating the relationship between catastrophizing and postoperative pain outcomes (pain intensity and analgesia use) in patients undergoing elective instrumented lumbar fusion ..
  18. ncbi The prevalence of postoperative pain in a sample of 1490 surgical inpatients
    M Sommer
    University Hospital Maastricht, Department of Anaesthesiology and Pain Treatment, Maastricht, The Netherlands
    Eur J Anaesthesiol 25:267-74. 2008
    To measure the prevalence of postoperative pain, an assessment was made of 1490 surgical inpatients who were receiving postoperative pain treatment according to an acute pain protocol.
  19. ncbi Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery
    Zeev N Kain
    Center for the Advancement of Perioperative Health, Department of Anesthesiology, Yale University School of Medicine, PO Box 208051, 333 Cedar St, New Haven, Connecticut 06521, USA
    Pediatrics 118:651-8. 2006
    ..To date, no similar investigation has ever been conducted in young children...
  20. ncbi Analysis of individual patient data from clinical trials: epidural morphine for postoperative pain
    R J Ni Mhuircheartaigh
    Pain Research and Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Level 6 West Wing, Oxford, UK
    Br J Anaesth 103:874-81. 2009
    ..Individual patient information from clinical trials is infrequently available, but can provide insights for clinical trials and practice...
  21. ncbi Can we predict persistent postoperative pain by testing preoperative experimental pain?
    Michal Granot
    University of Haifa, Mount Carmel, Haifa 31905, Israel
    Curr Opin Anaesthesiol 22:425-30. 2009
    Although it is recognized that medical and surgical procedures may lead to persistent postoperative pain, predicting which patients are at risk for developing chronic pain presents an ongoing challenge...
  22. ncbi The perioperative validity of the visual analog anxiety scale in children: a discriminant and useful instrument in routine clinical practice to optimize postoperative pain management
    Sophie Bringuier
    Department of Anesthesiology and Critical Care Medicine, Lapeyronie University Hospital, Montpellier, France
    Anesth Analg 109:737-44. 2009
    ..In this study, we evaluated psychometric properties of the visual analog scale (VAS)-anxiety for children and to study its perioperative relevance in clinical practice...
  23. ncbi Early failure of metal-on-metal bearings in hip resurfacing and large-diameter total hip replacement: A consequence of excess wear
    D J Langton
    North Tees and Hartlepool NHS Trust, Stockton on Tees and Centre for Rehabilitation, Newcastle University, Newcastle upon Tyne, England
    J Bone Joint Surg Br 92:38-46. 2010
    ..Surgeons must consider implant design, expected component size and acetabular component positioning in order to reduce early failures when performing large-bearing metal-on-metal hip resurfacing and replacement...
  24. ncbi Preemptive use of gabapentin significantly decreases postoperative pain and rescue analgesic requirements in laparoscopic cholecystectomy
    Chandra Kant Pandey
    Department of Anaesthesiology and Biostatistics, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
    Can J Anaesth 51:358-63. 2004
    To evaluate the comparative preemptive effects of gabapentin and tramadol on postoperative pain and fentanyl requirement in laparoscopic cholecystectomy.
  25. ncbi High-dose local infiltration analgesia after hip and knee replacement--what is it, why does it work, and what are the future challenges?
    Tord Röstlund
    Acta Orthop 78:159-61. 2007
  26. ncbi Gabapentin and postoperative pain--a systematic review of randomized controlled trials
    Kok Yuen Ho
    Department of Anesthesiology, Duke University Medical Center, Box 3094, Durham, NC 27710, USA
    Pain 126:91-101. 2006
    ..evaluate the efficacy and tolerability of perioperative gabapentin administration for the control of acute postoperative pain. We searched Medline (1966-2006), the Cochrane Library (2006), Scopus, CINAHL and bibliographies from ..
  27. ncbi A randomized, placebo-controlled trial of preoperative oral pregabalin for postoperative pain relief after minor gynecological surgery
    Michael J Paech
    Pharmacology and Anaesthesiology Unit, School of Medicine and Pharmacology, The University of Western Australia, Australia
    Anesth Analg 105:1449-53, table of contents. 2007
    ..The null hypothesis was that there was no significant difference in pain relief between pregabalin and placebo...
  28. pmc Age, gender, obesity, and depression are associated with patient-related pain and function outcome after revision total hip arthroplasty
    Jasvinder A Singh
    Department of Health Sciences Research, Mayo Clinic School of Medicine, Rochester, MN, USA
    Clin Rheumatol 28:1419-30. 2009
    ..7 (1.1, 2.7). Obesity and depression, considered modifiable clinical factors, were important independent predictors of pain, functional limitation and use of pain medications, following revision THA...
  29. ncbi Effectiveness of acute postoperative pain management: I. Evidence from published data
    S J Dolin
    Pain Clinic, St Richard s Hospital, Chichester PO19 4E, UK
    Br J Anaesth 89:409-23. 2002
    ..m.) analgesia, patient controlled analgesia (PCA), and epidural analgesia...
  30. pmc Functional recovery after open versus laparoscopic colonic resection: a randomized, blinded study
    Linda Basse
    Department of Surgical Gastroenterology, Copenhagen University Hospital, Hvidovre, Kettegaard Alle 30, DK 2650 Hvidovre, Denmark
    Ann Surg 241:416-23. 2005
    ..Since no comparative data between laparoscopic and open colonic resection with multimodal rehabilitation are available, the value of laparoscopy per se is unknown...
  31. ncbi Postoperative pain following coblation tonsillectomy: randomized clinical trial
    Nastasha Polites
    Department of Otolaryngology, Flinders Medical Centre and Flinders University, Adelaide, Australia
    ANZ J Surg 76:226-9. 2006
    Tonsillectomy is one of the commonest surgical procedures, with postoperative pain being an important source of morbidity...
  32. ncbi Pain and depression influence outcome 5 years after knee replacement surgery
    Victoria Brander
    Northwestern University Feinberg School of Medicine, Northwestern Orthopedic Institute, Chicago, IL 60611, USA
    Clin Orthop Relat Res 464:21-6. 2007
    ..Expansion of this tool to include measures sensitive to psychologic and other health factors should be considered...
  33. ncbi Postoperative pain management following caesarean section in University of Ilorin Teaching Hospital (UITH), Ilorin, Nigeria
    I K Kolawole
    Department of Anaesthesia, University of Ilorin Teaching Hospital UITH, Ilorin, Nigeria
    West Afr J Med 22:305-9. 2003
    ..To assess the common methods of analgesia used in our hospital following caesarean section, their effectiveness and patient satisfaction...
  34. ncbi Postoperative pain and convalescence in living kidney donors-laparoscopic versus open donor nephrectomy: a randomized study
    M H Andersen
    Department of Surgery, Rikshospitalet Radiumhospitalet University, Norway
    Am J Transplant 6:1438-43. 2006
    The aim of the present study was to compare postoperative pain and convalescence in patients randomized to laparoscopic or open donor surgery in a prospective, controlled trial...
  35. ncbi Perioperative intravenous lidocaine has preventive effects on postoperative pain and morphine consumption after major abdominal surgery
    Wolfgang Koppert
    Department of Anesthesiology, University of Erlangen, Erlangen, Germany
    Anesth Analg 98:1050-5, table of contents. 2004
    ..Lidocaine blood concentrations were measured. Postoperative pain ratings (numeric rating scale of 0-10) and morphine consumption (patient-controlled analgesia) were assessed ..
  36. ncbi Pulmonary function, postoperative pain, and serum cytokine level after lobectomy: a comparison of VATS and conventional procedure
    I Nagahiro
    Department of Surgery II, Okayama University Medical School, Japan
    Ann Thorac Surg 72:362-5. 2001
    ..Although lobectomy by the video-assisted thoracic surgical (VATS) approach is assumed to be less invasive than lobectomy by the standard posterolateral thoracotomy (PLT) approach, it has not been scientifically proven...
  37. pmc Reduced hospital stay, morphine consumption, and pain intensity with local infiltration analgesia after unicompartmental knee arthroplasty
    Per Essving
    Department of Orthopedic Surgery, University of Linkoping, Sweden
    Acta Orthop 80:213-9. 2009
    The degree of postoperative pain is usually moderate to severe following knee arthroplasty. We investigated the efficacy of local administration of analgesics into the operating area, both intraoperatively and postoperatively.
  38. ncbi Pseudotumours associated with metal-on-metal hip resurfacings
    H Pandit
    Nuffield Orthopaedic Centre, Oxford, England
    J Bone Joint Surg Br 90:847-51. 2008
    ..We are concerned that with time the incidence of these pseudotumours may increase. Further investigation is required to define their cause...
  39. ncbi Efficacy of continuous wound catheters delivering local anesthetic for postoperative analgesia: a quantitative and qualitative systematic review of randomized controlled trials
    Spencer S Liu
    Department of Anesthesiology, Hospital for Special Surgery and the Weill College of Medicine of Cornell University, New York, NY 10021, USA
    J Am Coll Surg 203:914-32. 2006
  40. pmc The John Insall Award: gender-specific total knee replacement: prospectively collected clinical outcomes
    Steven J MacDonald
    Division of Orthopaedic Surgery, University of Western Ontario and London Health Sciences Centre, University Campus, London, ON, Canada
    Clin Orthop Relat Res 466:2612-6. 2008
    ..The data refute the hypothesis of inferior clinical outcome for women following total knee arthroplasty when using standard components...
  41. ncbi Effectiveness of transcutaneous electrical nerve stimulation on postoperative pain with movement
    Barbara Rakel
    Department of Nursing Services and Patient Care, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
    J Pain 4:455-64. 2003
    ..The lack of effect on pain at rest supports the hypothesis that TENS works through reducing hyperalgesia...
  42. ncbi Postoperative analgesia in total hip arthroplasty: a randomized double-blinded, placebo-controlled study on peroperative and postoperative ropivacaine, ketorolac, and adrenaline wound infiltration
    Lasse Juel Andersen
    Department of Orthopaedic Surgery, Odense University Hospital, Middelfart, Denmark
    Acta Orthop 78:187-92. 2007
    ..Comfort and lack of pain are important for optimal mobilization after hip replacement. We investigated the efficacy of double wound infiltration...
  43. ncbi Remifentanil-induced postoperative hyperalgesia and its prevention with small-dose ketamine
    Vincent Joly
    Department of Anesthesia, Institut National de la Santé et de la Recherche Médicale INSERM E 332, Hopital Ambroise Pare, Assistance Publique Hopitaux de Paris, France
    Anesthesiology 103:147-55. 2005
    ....
  44. ncbi Ketamine and postoperative pain--a quantitative systematic review of randomised trials
    Nadia Elia
    EBCAP Institute Evidence Based Critical care, Anaesthesia and Pain treatment, Division of Anaesthesiology, Geneva University Hospitals, 24 Rue Micheli du Crest, CH 1211 Geneva 14, Switzerland
    Pain 113:61-70. 2005
    ..Benefits and risks of ketamine for the control of postoperative pain are not well understood...
  45. ncbi The efficacy of preemptive analgesia for acute postoperative pain management: a meta-analysis
    Cliff K S Ong
    Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, National University of Singapore
    Anesth Analg 100:757-73, table of contents. 2005
    Whether preemptive analgesic interventions are more effective than conventional regimens in managing acute postoperative pain remains controversial...
  46. ncbi Acute and nonacute complications associated with interscalene block and shoulder surgery: a prospective study
    A Borgeat
    Department of Anesthesiology, Orthopedic University Clinic Zurich Balgrist, Zurich, Switzerland
    Anesthesiology 95:875-80. 2001
    ..The incidence, etiology, and evolution of complications after interscalene brachial plexus block (ISB) are not well-known. The authors prospectively monitored 521 patients for complications during the first 9 months after ISB...
  47. pmc Predictors of patient relevant outcome after total hip replacement for osteoarthritis: a prospective study
    A K Nilsdotter
    Department of Orthopaedics, Lund University Hospital, Spenshult Hospital of Rheumatic Diseases, Halmstad, Sweden
    Ann Rheum Dis 62:923-30. 2003
    ..To investigate prospectively long term patient relevant outcomes after unilateral total hip replacement (THR) for osteoarthritis (OA). To identify non-responders to this intervention and patient related predictors of unsatisfactory outcome...
  48. ncbi A multimodal analgesia protocol for total knee arthroplasty. A randomized, controlled study
    Pascal André Vendittoli
    Orthopaedic Surgery Unit, Department of Surgery, Maisonneuve Rosemont Hospital, 5345 Boul L Assomption, Suite 55, Montreal, Quebec H1T 4B3, Canada
    J Bone Joint Surg Am 88:282-9. 2006
    ..to improve pain control after total knee arthroplasty, parenteral narcotics still play a major role in postoperative pain management...
  49. ncbi Pharmacokinetics and efficacy of ropivacaine continuous wound instillation after joint replacement surgery
    M Bianconi
    Department of Anesthesiology and Intensive Care, St Anna Hospital Ferrara, Ferrara, Italy
    Br J Anaesth 91:830-5. 2003
    ....
  50. ncbi The risk of severe postoperative pain: modification and validation of a clinical prediction rule
    Kristel J M Janssen
    Julius Center for Health Sciences and Primary Care, Department of Anesthesiology, University Medical Center Utrecht, PO Box 85500, 3508 GA Utrecht, The Netherlands
    Anesth Analg 107:1330-9. 2008
    ..Subsequently, we prospectively tested the modified rule in patients who underwent surgery later in time and in another hospital (external validation)...
  51. ncbi Early postoperative pain management after thoracic surgery; pre- and postoperative versus postoperative epidural analgesia: a randomised study
    Arif Yegin
    Department of Anaesthesiology, Akdeniz University Medical Faculty, Antalya, Turkey
    Eur J Cardiothorac Surg 24:420-4. 2003
    ..In this study, we assessed preoperative and postoperative thoracic epidural analgesia (Preop-TEA and Postop-TEA) techniques on post-thoracotomy pain in 61 patients undergoing posterolateral thoracotomy...
  52. ncbi The exploration of the establishment of cutpoints to categorize the severity of acute postoperative pain
    Alfhild Dihle
    Faculty of Nursing, Oslo University College, Oslo, Norway
    Clin J Pain 22:617-24. 2006
    ..for a variety of chronic pain conditions, only one study by Mendoza and colleagues reported on CPs for acute postoperative pain that were derived using ratings of worst pain...
  53. ncbi Predictive factors of postoperative pain after day-case surgery
    Hans Fritz Gramke
    Department of Anesthesiology and Pain Therapy, University Hospital Maastricht, Maastricht, The Netherlands
    Clin J Pain 25:455-60. 2009
    Despite the growing number of ambulatory operations knowledge of predictive factors of postoperative pain after ambulatory surgery is limited...
  54. ncbi Review of the use of gabapentin in the control of postoperative pain
    Jefferson Clivatti
    Universidade Federal de Sao Paulo
    Rev Bras Anestesiol 59:87-98. 2009
    Gabapentin has been used as adjuvant in the treatment of postoperative pain with a neuropathic component. It is responsible for the inhibition of central sensitization, decreasing postoperative pain.
  55. ncbi Neuropathic pain following breast cancer surgery: proposed classification and research update
    Beth F Jung
    Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 604, Rochester, NY 14642, USA
    Pain 104:1-13. 2003
  56. ncbi Risk factors for chronic pain after hysterectomy: a nationwide questionnaire and database study
    Birgitte Brandsborg
    Danish Pain Research Center, Aarhus University Hospital, Aarhus, Denmark
    Anesthesiology 106:1003-12. 2007
    ..This nationwide questionnaire and database study describes pain and identifies risk factors for chronic postsurgical pain 1 yr after hysterectomy for benign indications...
  57. ncbi The relationship of intracanal medicaments to postoperative pain in endodontics
    E H Ehrmann
    School of Dental Science, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, 711 Elizabeth Street, Melbourne, Victoria, 3000, Australia
    Int Endod J 36:868-75. 2003
    To investigate the relationship of postoperative pain to three different medicaments placed in the root canal after a complete biomechanical debridement of the root canal system in patients presenting for emergency relief of pain.
  58. ncbi The impact of preoperative information on state anxiety, postoperative pain and satisfaction with pain management
    Mats Sjöling
    Department of Nursing and Health Sciences, Mid Sweden University, Sundsvall, Sweden
    Patient Educ Couns 51:169-76. 2003
    ..The postoperative pain declined more rapidly for patients in the treatment group, the degree of preoperative state anxiety was ..
  59. ncbi High and low frequency TENS reduce postoperative pain intensity after laparoscopic tubal ligation: a randomized controlled trial
    Josimari M Desantana
    Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, IA, USA
    Clin J Pain 25:12-9. 2009
    Transcutaneous electrical nerve stimulation (TENS) is an effective adjunctive therapy for postoperative pain; however, effects of different frequencies of stimulation have not been systematically investigated...
  60. ncbi A mouse model of incisional pain
    Esther M Pogatzki
    Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Anesthesiology 99:1023-7. 2003
  61. ncbi Mandibular third molar removal: risk indicators for extended operation time, postoperative pain, and complications
    Ingibjörg S Benediktsdóttir
    Faculty of Odontology, University of Iceland, Reykjavik
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 97:438-46. 2004
    ..The aim of this study was to identify risk indicators for extended operation time and postoperative complications after removal of mandibular third molars...
  62. ncbi Application of a locally placed anesthesia catheter for reduction of postoperative pain after mastectomy for breast cancer
    Volker R Jacobs
    Department of Surgery, Fayette Medical Center FMC, Fayette, AL, USA
    Int J Fertil Womens Med 51:225-9. 2006
    b>Postoperative pain management is important, especially in cancer patients...
  63. ncbi Physical and psychological morbidity after axillary lymph node dissection for breast cancer
    T F Hack
    University of Manitoba, Winnipeg, Canada
    J Clin Oncol 17:143-9. 1999
    ..Although potential negative side effects associated with ALND are known, we set out to examine whether these side effects contribute significantly to patient reports of quality of life and mental health...
  64. ncbi Preoperative emotional states in patients with breast cancer and postoperative pain
    G Ozalp
    Department of Anesthesiology, Ankara Oncology Hospital, Turkey
    Acta Anaesthesiol Scand 47:26-9. 2003
    ..The present study examined the relationship between psychological variables, including anxiety, depression, and patient-controlled analgesia (PCA) use in patients who underwent radical mastectomy...
  65. ncbi Postoperative pain assessment with three intensity scales in Chinese elders
    Li Li
    Department of Nursing, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China
    J Nurs Scholarsh 41:241-9. 2009
    ..To evaluate the reliability and validity of the Faces Pain Scale Revised (FPS-R), the Numeric Rating Scale (NRS), and the Iowa Pain Thermometer (IPT) for pain assessment in Chinese elders who have had surgery...
  66. ncbi Using the American Pain Society's patient outcome questionnaire to evaluate the quality of postoperative pain management in a sample of Norwegian patients
    Alfhild Dihle
    Faculty of Nursing, Oslo University College, Oslo, Norway
    J Pain 7:272-80. 2006
    ..with function, and in the doses of analgesics administered; to describe patients' level of satisfaction with postoperative pain management; and to determine the relationships between pain severity and patient outcomes...
  67. ncbi Predictors of acute postoperative pain after elective surgery
    Michael Sommer
    Department of Anaesthesiology and Pain Treatment, University Hospital Maastricht, 6202 AZ Maastricht, The Netherlands
    Clin J Pain 26:87-94. 2010
    Objectives:Despite efforts to improve acute postoperative pain management, a substantial number of patients still experience moderate to severe pain during the immediate postoperative days...
  68. ncbi Efficacy and safety of patient-controlled opioid analgesia for acute postoperative pain. A quantitative systematic review
    B Walder
    Division of Surgical Intensive Care, Department APSIC, Geneva University Hospitals, Geneva, Switzerland
    Acta Anaesthesiol Scand 45:795-804. 2001
    ..The usefulness of intravenous patient-controlled analgesia (PCA) with opioids for postoperative analgesia is not well defined...
  69. ncbi Predictors of postoperative pain and analgesic consumption: a qualitative systematic review
    Hui Yun Vivian Ip
    Department of Anesthesiology, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Anesthesiology 111:657-77. 2009
    ..Effective control of postoperative pain is important after anesthesia and surgery...
  70. ncbi Systemic postoperative pain management following minimally invasive pectus excavatum repair in children and adolescents: a retrospective comparison of intravenous patient-controlled analgesia and continuous infusion with morphine
    Danguole Ceslava Rugyte
    Department of Anesthesiology, Kaunas University of Medicine, Kaunas, Lithuania
    Pediatr Surg Int 26:665-9. 2010
    Optimal postoperative pain management following minimally invasive surgical repair of pectus excavatum is not established...
  71. ncbi Postoperative pain intensity assessment: a comparison of four scales in Chinese adults
    Li Li
    Department of Nursing, Zhujiang Hospital, Southern Medical University, Guangzhou, China
    Pain Med 8:223-34. 2007
    ..To determine the psychometric properties and applicability of four pain scales in Chinese postoperative adults...
  72. ncbi Control of acute postoperative pain by transcutaneous electrical nerve stimulation after open cardiac operations: a randomized placebo-controlled prospective study
    Mustafa Emmiler
    Department of Cardiovascular Surgery, Afyon Kocatepe University, School of Medicine, Afyon, Turkey
    Heart Surg Forum 11:E300-3. 2008
    ..We investigated the effectiveness of transcutaneous electrical nerve stimulation (TENS) therapy on pain during the first 24 hours after a cardiac surgical procedure...
  73. ncbi The effect of addition of intrathecal clonidine to hyperbaric bupivacaine on postoperative pain and morphine requirements after Caesarean section: a randomized controlled trial
    I van Tuijl
    Department of Anesthesiology, University Medical Center Utrecht, The Netherlands
    Br J Anaesth 97:365-70. 2006
    ..We investigated the effect of the addition of clonidine (75 microg) to hyperbaric bupivacaine on postoperative morphine consumption after Caesarean section in a randomized controlled double-blind trial...
  74. ncbi Environmental and genetic factors associated with morphine response in the postoperative period
    Laurent Coulbault
    Pharmacology Department, Saint Antoine University of Medicine, University Pierre et Marie Curie, Paris, France
    Clin Pharmacol Ther 79:316-24. 2006
    ..The aim of this study was to investigate the respective influence of genetic and nongenetic factors on morphine dose requirements and adverse effects after colorectal surgery...
  75. ncbi Perioperative small-dose S(+)-ketamine has no incremental beneficial effects on postoperative pain when standard-practice opioid infusions are used
    Wolfgang Jaksch
    Department of Anesthesiology and Intensive Care Medicine, Ludwig Boltzmann Institute of Experimental Anesthesiology and Research in Intensive Care Medicine, Wilhelminenspital, Vienna, Austria
    Anesth Analg 94:981-6, table of contents. 2002
    ..In our study, S(+)-ketamine did not contribute to postoperative pain reduction, possibly because of the clinically routine perioperative opioid analgesia.
  76. ncbi Comparison of visual analogue scale and faces rating scale in measuring acute postoperative pain
    Lida Fadaizadeh
    National Research Institute of Tuberculosis and Lung Disease, Masih Daneshvari Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Iran
    Arch Iran Med 12:73-5. 2009
    ..Visual analogue scale and faces rating scale are two pain assessment tools that can be used interchangeably for evaluation of acute postoperative pain.
  77. ncbi Evaluation of the efficacy of a novel electronic pain assessment device, the Pain Gauge, for measuring postoperative pain in rats
    C A Richardson
    Comparative Biology Centre, Medical School, Framlington Place, University of Newcastle, Newcastle upon Tyne NE2 4HH, UK
    Lab Anim 41:46-54. 2007
    ..To establish whether the Pain Gauge is effective in assessing postoperative pain in laboratory rats, preoperative and postoperative pain gauge scores ('pain scores') were obtained from 67 ..
  78. pmc Efficacy of perioperative parecoxib injection on postoperative pain relief after laparoscopic cholecystectomy: a prospective, randomized study
    Thawatchai Akaraviputh
    Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Prannok Road, Bangkok, Thailand
    World J Gastroenterol 15:2005-8. 2009
    To determine the efficacy of perioperative parecoxib injection on postoperative pain relief after laparoscopic cholecystectomy.
  79. ncbi Acute postoperative pain predicts chronic pain and long-term analgesic requirements after breast surgery for cancer
    A Fassoulaki
    Department of Anaesthesia, Aretaieio Hospital, Medical School, University of Athens, Athens, Greece
    Acta Anaesthesiol Belg 59:241-8. 2008
    b>Postoperative pain and analgesic requirements may be associated with chronic pain. The aim of the study was to investigate this association...
  80. ncbi Correlates of postoperative pain and intravenous patient-controlled analgesia use in younger and older surgical patients
    Lucia Gagliese
    School of Kinesiology and Health Science, York University, Ontario, Canada
    Pain Med 9:299-314. 2008
    Age-related patterns in postoperative pain are unclear with reports of no age differences and less pain with age. The objective of this study was to identify correlates of pain and intravenous patient-controlled analgesia (i.v...
  81. ncbi Effect of analgesic standards on persistent postoperative pain evoked by skin/muscle incision and retraction (SMIR)
    Sarah J L Flatters
    Wolfson Centre for Age Related Diseases, Centre for Integrative Biomedicine, King s College London, Hodgkin Building, Guy s Campus, London SE11UL, UK
    Neurosci Lett 477:43-7. 2010
    ..and inguinal hernia repair involve essential prolonged tissue retraction, often causing persistent postoperative pain. A new model was developed to mimic this clinical scenario, whereby skin/muscle incision and retraction (..
  82. ncbi Postoperative pain in multiple-visit and single-visit root canal treatment
    Abdel Hameed H El Mubarak
    Conservative Dentistry Division, Department of Oral Rehabilitation, Faculty of Dentistry, University of Khartoum, Khartoum, Sudan
    J Endod 36:36-9. 2010
    The purpose of the present study was to evaluate postoperative pain after root canal treatment at the Department of Conservative Dentistry, Faculty of Dentistry, University of Khartoum, Sudan.
  83. ncbi The prevalence of postoperative pain and flare-up in single- and multiple-visit endodontic treatment: a systematic review
    C Sathorn
    Endodontic Unit, School of Dental Science, University of Melbourne, Melbourne, Vic, Australia
    Int Endod J 41:91-9. 2008
    The aim of this systematic review was to assess the evidence regarding postoperative pain and flare-up of single- or multiple-visit root canal treatment.
  84. ncbi Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain
    Cliff K S Ong
    Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, National University of Singapore, Republic of Singapore
    Anesth Analg 110:1170-9. 2010
    ..We evaluated the efficacy of the combination of paracetamol and an NSAID versus either drug alone in various acute pain models...
  85. ncbi The associations between severity of early postoperative pain, chronic postsurgical pain and plasma concentration of stable nitric oxide products after breast surgery
    Gabriella Iohom
    Department of Anesthesia and Intensive Care Medicine, Cork University Hospital, Cork, Ireland
    Anesth Analg 103:995-1000. 2006
    ..of chronic postsurgical pain (CPSP) after breast surgery and sought to determine the association among early postoperative pain, NOx, and the likelihood of subsequent development of CPSP...
  86. ncbi Postoperative pain after the application of two different irrigation devices in a prospective randomized clinical trial
    Eudes Gondim
    Department of Endodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Endod 36:1295-301. 2010
    The extrusion of irrigation solutions beyond the apical constriction may result in postoperative pain. Sodium hypochlorite can cause severe tissue irritation and necrosis outside the root canal system if extruded into the periodontal ..
  87. ncbi The effect of music on postoperative pain and anxiety
    Kelly D Allred
    University of Central Florida, Orlando, Florida, USA
    Pain Manag Nurs 11:15-25. 2010
    ..Nurses can offer music as an intervention to decrease pain and anxiety in this patient population with confidence, knowing there is evidence to support its efficacy...
  88. ncbi Effects of pulsed electromagnetic fields on postoperative pain: a double-blind randomized pilot study in breast augmentation patients
    Per Hedén
    Department of Plastic Surgery, Akademikliniken, Storängsvägen 10, 115 42, Stockholm, Sweden
    Aesthetic Plast Surg 32:660-6. 2008
    b>Postoperative pain may be experienced after breast augmentation surgery despite advances in surgical techniques which minimize trauma...
  89. ncbi Comparison of continuous and intermittent transcutaneous electrical nerve stimulation in postoperative pain management after coronary artery bypass grafting: a randomized, placebo-controlled prospective study
    Ozlem Solak
    Department of Physical Medicine and Rehabilitation, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey
    Heart Surg Forum 12:E266-71. 2009
    ..We compared the effectiveness of continuous transcutaneous electrical nerve stimulation (TENS) and intermittent TENS in the management of pain after coronary artery bypass grafting (CABG)...
  90. ncbi A new knee surgery model in rats to evaluate functional measures of postoperative pain
    Asokumar Buvanendran
    Department of Anesthesiology, Rush University Medical College, Chicago, IL, USA
    Anesth Analg 107:300-8. 2008
    ..We used a new animal knee surgery model to characterize pain-related behavior in the rat, and its therapeutic modulation with systemic and intrathecal drug treatment...
  91. ncbi Pain relief after arthroscopic shoulder surgery: a comparison of intraarticular analgesia, suprascapular nerve block, and interscalene brachial plexus block
    François J Singelyn
    Department of Anesthesiology, School of Medicine, Catholic University of Louvain, St Luc Hospital, Avenue Hippocrate 10 1821, B 1200 Brussels, Belgium
    Anesth Analg 99:589-92, table of contents. 2004
    ..We conclude that ISB is the most efficient analgesic technique after arthroscopic acromioplasty. SSN block would be a clinically appropriate alternative...
  92. ncbi The prevalence of postoperative pain in a cross-sectional group of patients after day-case surgery in a university hospital
    Hans Fritz Gramke
    Department of Anesthesiology and Pain Therapy, University Hospital Maastricht, Maastricht, The Netherlands
    Clin J Pain 23:543-8. 2007
    Although a great variety of surgical procedures are performed on an ambulatory basis, little is known about postoperative pain experience at home after ambulatory surgery...
  93. pmc Morphine tolerance attenuates the resolution of postoperative pain and enhances spinal microglial p38 and extracellular receptor kinase phosphorylation
    R J Horvath
    Department of Pharmacology, Dartmouth Medical School, Hanover, NH 03755, USA
    Neuroscience 169:843-54. 2010
    Persistent postoperative pain is a very common phenomenon which severely affects the lives of patients who develop it following common surgical procedures...
  94. ncbi Postoperative pain in older people: a review of the literature
    Morag Prowse
    Faculty of Health and Social Work, University of Plymouth, Drake Circus, Plymouth, UK
    J Clin Nurs 16:84-97. 2007
    ..The literature review was conducted to explore those factors which complicate pain management in older people to inform future research, education and nursing practice in this area...
  95. ncbi Influence of thoracic epidural analgesia on postoperative pain relief and ileus after laparoscopic colorectal resection : Benefit with epidural analgesia
    Urs Zingg
    Department of Surgery, University Hospital, Spitalstr 21, Basel, 4031, Switzerland
    Surg Endosc 23:276-82. 2009
    ..However, in laparoscopic colorectal surgery the role of TEA is not well defined. This prospective observational study investigates the influence of TEA in laparoscopic colorectal resections...
  96. ncbi Evaluation of a single preoperative dose of pregabalin for attenuation of postoperative pain after laparoscopic cholecystectomy
    A Agarwal
    Department of Anaesthesiology, Sanjay Gandhi Post GraduateInstitute of Medical Sciences, Type V B 11, Lucknow 226014, India
    Br J Anaesth 101:700-4. 2008
    b>Postoperative pain is the dominating complaint and the primary reason for prolonged convalescence after laparoscopic cholecystectomy...
  97. ncbi The use of brain positron emission tomography to identify sites of postoperative pain processing with and without epidural analgesia
    Asokumar Buvanendran
    Department of Anesthesiology, Rush University Medical Center, Chicago, Illinois 60612, USA
    Anesth Analg 105:1784-6, table of contents. 2007
    It is not known how different analgesic regimes affect the brain when reducing postoperative pain. We performed positron emission tomography (PET) scans on a 69-yr-old woman in the presence of moderate postoperative pain and then with ..
  98. ncbi Effects of minimal invasive coronary artery bypass on pulmonary function and postoperative pain
    A Lichtenberg
    Division of Thoracic and Cardiovascular Surgery, Hannover Medical School, Germany
    Ann Thorac Surg 70:461-5. 2000
    ..We investigated whether this fact may lead to less postoperative pain and improved pulmonary function.
  99. ncbi Epidural dexamethasone reduces postoperative pain and analgesic requirements
    Siji Thomas
    Department of Anaesthesiology, Amala Institute of Medical Sciences, Thrissur, Kerala 680555, India
    Can J Anaesth 53:899-905. 2006
    ..We therefore undertook a study to evaluate the efficacy of epidurally administered dexamethasone in reducing postoperative morphine requirements, as a measure of analgesia following laparoscopic cholecystectomy...
  100. ncbi The effect of perioperative intravenous lidocaine on postoperative pain and immune function
    Israel Z Yardeni
    Department of Anesthesiology, Rabin Medical Center, Hasharon Hospital, Sackler School of Medicine, Tel Aviv University, Israel
    Anesth Analg 109:1464-9. 2009
    ..We focused on the effects of preincisional and intraoperative IV lidocaine on pain intensity and immune reactivity in the postoperative period...
  101. ncbi Pregabalin and dexamethasone for postoperative pain control: a randomized controlled study in hip arthroplasty
    O Mathiesen
    Department of Anaesthesia, Copenhagen University Hospital, Ndr Ringvej, DK 2600 Glostrup, Denmark
    Br J Anaesth 101:535-41. 2008
    ..Optimal pain treatment with minimal side-effects is essential for early mobility and recovery in patients undergoing total hip arthroplasty. We investigated the analgesic effect of pregabalin and dexamethasone in this surgical procedure...

Research Grants63

  1. Novel drug combinations for the management of pain
    KENNETH NARDUCY; Fiscal Year: 2007
    ..we will conduct Phase I human clinical trials to evaluate tolerability and oral bioavailability in normal human volunteers, and Phase II human clinical trials to evaluate the combinations in postoperative pain patients.
  2. Clinical Development of Hemostatic Agent ClotFoam for Severe Hemorrhage
    Maja Nowakowski; Fiscal Year: 2013
    ..a non- compressible hemostatic control in laparoscopic surgery will result in reduction of blood loss, postoperative pain, hospital stay and complications following these procedures...
  3. 3D Single Fiber Endoscope for Minimally Invasive Surgeries
    Jason Geng; Fiscal Year: 2013
    ..has lead to reduced risk of complications, faster recovery with enhanced patient satisfaction due to reduced postoperative pain and favorable health system economics...
  4. Regulation of TRPV1 and Nociceptor Sensitization by the Complement System
    Yuriy M Usachev; Fiscal Year: 2013
    ..or antagonizing their receptors produces analgesic effects in animal models of inflammatory, neuropathic and postoperative pain. Moreover, direct administration of the complement fragments increases nociceptive sensitivity to heat and ..
  5. Comparing focused ultrasound and uterine artery embolization for uterine fibroids
    Elizabeth A Stewart; Fiscal Year: 2010
    ..This myoma-specific approach causes less postoperative pain and allows for outpatient treatment but is less comprehensive and may lead to less long term symptomatic ..
  6. Transcranial Direct Current Stimulation in the Management of Post-operative Pain
    Jeffrey J Borckardt; Fiscal Year: 2013
    ..the procedure itself is associated with considerable post-operative pain lasting days to weeks, and adequate postoperative pain control is an important factor in determining recovery time and hospital length of stay...
  7. Role of the Supraspinal Opioidergic Circuit in Prefrontal TMS-Induced Analgesia
    JOSEPH JEFFREY TAYLOR; Fiscal Year: 2013
    ..with narcotic analgesics demonstrate an urgent need to discover adjunctive therapies for chronic and postoperative pain. This study uses rTMS as an interventional tool to study pain circuitry while simultaneously evaluating its ..
  8. Role of glial derived prostaglandins in pain due to surgery
    CHRISTOPHER MICHAEL PETERS; Fiscal Year: 2010
    The management of postoperative pain is a continuing clinical challenge in the United States and worldwide for individuals undergoing surgical procedures...
  9. Pathophysiology of postoperative delirium in older patients
    Jacqueline M Leung; Fiscal Year: 2013
    ..of pain, and probably to the central nervous system effects of opioid analgesics, the usual therapy for postoperative pain. In our framework, the presence of risks for delirium such as advanced age, cognitive impairment, depression,..
  10. Obesity and Surgical Outcomes
    Jeffrey H Silber; Fiscal Year: 2010
    ..to normal weight patients, such as differences in the surgical procedures offered, anesthesia technique and postoperative pain control...
  11. Postoperative pain increases synaptic GluA1 expression in the nucleus accumbens t
    Jing Wang; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Depressed mood is a common feature of both acute and chronic postoperative pain. The nucleus accumbens (NAc), the reward center of the brain, may be a key region to regulate pain-induced depression...
  12. Parent/Health Care Provider Behaviors &Child's Anxiety
    Zeev Kain; Fiscal Year: 2013
    ..Secondary aims of the study are to: 1. Examine the impact of P-TIPS on surgical recovery parameters such as postoperative pain, recovery room stay, nausea and vomiting, emergence delirium and maladaptive behavioral changes;2...
  13. Development of a new technology for assessing pediatric pain (NTAP)
    Jeannie S Huang; Fiscal Year: 2013
    ..project will collect a dataset of clinical pain in children following a known pain insult (pancreatitis, and postoperative pain following appendectomy...
  14. Mastectomy Reconstruction Outcome Consortium (MROC Study)
    Edwin G Wilkins; Fiscal Year: 2013
    ..Outcomes assessed will include complications, postoperative pain, psychosocial well-being, physical functioning, patient satisfaction and costs...
  15. Evaluation of Sodium Channel Inhibitors as Therapeutics for Chronic Muscle Disord
    JOHN VINCENT MULCAHY; Fiscal Year: 2013
    ..effects than existing pharmacological treatment options for anal fissure, chronic tension-type headache, postoperative pain, and other medical conditions...
  16. Controlling Pain After Trauma
    David R Patterson; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The treatment of postoperative pain after severe trauma is poorly understood, and it can lead to chronic pain, opiate drug addiction and elevated health care costs...
  17. Ethnic Differences in Acute Pain and Analgesic Response
    Barbara A Hastie; Fiscal Year: 2010
    ..We will assess preoperative experimental pain responses and psychosocial measures. We will monitor postoperative pain levels along with PK and PD responses to the opioid fentanyl...
  18. BEHAVIORAL EFFECTS OF OPIOIDS IN VOLUNTEERS
    James Zacny; Fiscal Year: 2003
    ..methodology to examine the effects of a number of different opioids that are typically given to patients for postoperative pain. This application will have four series of studies that are logical continuations of studies from the ..
  19. Mechanisms Involved in the Transition of Acute to Chronic Pain after Surgery
    CHRISTOPHER MICHAEL PETERS; Fiscal Year: 2013
    ..This is due in part to an incomplete knowledge of the mechanisms responsible for the transition of postoperative pain from an acute phenomenon that resolves after the surgical site heals to a chronic pain state...
  20. Use of Machine Learning Classifiers to Forecast Severe Acute Postoperative Pain F
    Patrick Tighe; Fiscal Year: 2013
    ..To accurately forecast severe postoperative pain, we propose the use of machine learning classifiers (MLC's), which are classification algorithms ..
  21. Resolvins, protectins, and chronic pain resolution.
    CHARLES NICHOLAS SERHAN; Fiscal Year: 2013
    ..work in progress, the results from the proposed studies will be transformative and have considerable impact on the entire pain community, from acute postoperative pain to chronic inflammatory pain and neuropathic pain.
  22. Laser-Activated Collagen Adhesives for Herniorrhaphy
    Barbara Soltz; Fiscal Year: 2006
    ..that frequently occurs with mechanical mesh fixation, inhibit adhesion formation, beneficial in minimizing postoperative pain due to tissue ischemia and nerve entrapment syndromes and is inherently compliant with laparoscopic formats...
  23. Management of Post Operative Pain in Underserved Populations
    Zeev Kain; Fiscal Year: 2013
    ..the past decade outpatient surgery has become much more prevalent and as a result the burden of managing postoperative pain at home falls mostly on the parents...
  24. Voltage gated sodium channels in acute post laminectomy pain
    CHRISTINA MARIE SPOFFORD; Fiscal Year: 2013
    ..For many patients, postoperative pain is poorly controlled despite treatment with conventional therapeutics...
  25. A Unified Surgical Instrument System for Periodontal Minimally Invasive Surgery
    STEPHEN HARREL; Fiscal Year: 2007
    ..surgery, has a record of clinical regeneration of lost tissue, results in less patient trauma, less postoperative pain, better post surgical esthetics, and a more rapid return to normal function...
  26. EFFECT OF NURSING ACTIONS TO ALLEVIATE PAIN IN CHILDREN
    MARY DENYES; Fiscal Year: 1992
    ..practice in a children's hospital to determine the effect of the experimental protocols on intensity of postoperative pain. A modified randomized blocks design with repeated measures will be used to address the following research ..
  27. Supplementing Relaxation & Music for Postoperative Pain
    Marion Good; Fiscal Year: 2004
    Despite decades of research on postoperative pain, it is still not being relieved. To date there has been no clinical trial that integrates testing of both pharmacological and nonpharmacological methods of pain relief...
  28. Development of Novel Therapeutics for Postsurgical Pain
    KENNETH NARDUCY; Fiscal Year: 2003
    ..We will further test and develop this drug in Phase II for treating postoperative pain and for other analgesic treatments where acetaminophen is contraindicated...
  29. Effects of Physiotones on Adolescents' Pain
    Bernice Mowery; Fiscal Year: 2003
    Effective postoperative pain management is a high priority outcome for children and their families...
  30. DEVELOPMENT OF ANALGESICS WITH FEWER SIDE EFFECTS
    KENNETH NARDUCY; Fiscal Year: 2000
    ..will identify lead candidate drug(s) that we will further test and develop in phase II for the treatment of postoperative pain, pain associated with pneumonia, chronic pain, phantom limb pain, and for analgesic treatment where ..
  31. Elder Surgery-Functional Recovery after Beta Blockade
    Jeffrey Silverstein; Fiscal Year: 2006
    ..regimen; 2) comparison of the course of early (stage 1 and 2) recovery with particular reference to postoperative pain and analgesic medications in elderly surgical patients receiving either a control or an anesthetic-coupled ..
  32. Laser-Activated Collagen Adhesives for Herniorrhaphy
    Barbara Soltz; Fiscal Year: 2002
    ..injury which frequently occurs with mechanical fixation and may offer the additional benefit of minimizing postoperative pain due to tissue ischemia and nerve entrapment syndromes...
  33. An Innovative Assessment of Adult Influences on Children's Postoperative Pain
    Zeev Kain; Fiscal Year: 2009
    ..such as opioids and non-steroidal anti-inflammatory agents are generally considered the first line of postoperative pain management...
  34. The Effect of Postoperative Analgesics on Sleep of Rats
    Sharon Kozachik; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Pain and sleep disturbance are significant public health problems. Postoperative pain and sleep disturbance are inter-related sequelae that can adversely affect recovery if not effectively managed...
  35. MECHANISMS OF POSTOPERATIVE PAIN
    Timothy Brennan; Fiscal Year: 2001
    ..from the applicant'S abstract) In this FIRST award proposal, the investigator proposes to use a rat model of postoperative pain that he has developed...
  36. Development of Non-Narcotic Intravenous Analgesics
    KENNETH NARDUCY; Fiscal Year: 2007
    ..will fulfill one of our target profiles, defined as a drug that is clinically useful as an IV treatment for postoperative pain and other types of pain, including patients that may have compromised liver function (eg...
  37. POSTOPERATIVE PAIN COMMUNICATION SKILLS FOR OLDER ADULTS
    Deborah McDonald; Fiscal Year: 1999
    ..b>Postoperative pain will be measured with the Short Form McGill Pain Questionnaire on postoperative day 1, and 2, and 1 and 7 ..
  38. Psychological Influences on Postoperative Recovery
    Zeev Kain; Fiscal Year: 2007
    ..we have demonstrated that high levels of preoperative anxiety in children are associated with increased postoperative pain and impaired clinical and behavioral postoperative recovery...
  39. DISTRIBUTION AND ULTRASTRUCTURE OF DENTAL INNERVATION
    MARGARET BYERS; Fiscal Year: 2003
    ..interactions with pulp and dentin in normal teeth, and the mechanisms that cause hypersensitive dentin, postoperative pain, and difficult anesthesia for inflamed teeth...
  40. Neural blockade with vanilloids
    Igor Kissin; Fiscal Year: 2007
    ..To study the specific aims of the project the effects of RTX will be examined in rats by behavioral methods; and whole cell voltage-clamp technique will be used to identify a mechanism for impulse failure induced by RTX. ..
  41. IMAGE REPRESENTATION IN THE PRIMARY VISUAL CORTEX
    Allan Gottschalk; Fiscal Year: 2002
    ..In addition, this material provides an important quantitative link between biologic and synthetic methods of image representation. ..
  42. ACUTE TOLERANCE IN ANESTHETIC ACTIONS AND INTERACTIONS
    Igor Kissin; Fiscal Year: 2001
    ....
  43. TRPV1 Expressing Sensory Afferents in Postoperative Pain
    Timothy Brennan; Fiscal Year: 2009
    ..A separate pathway, likely an A-fiber mediated pathway, is sufficient to transmit the enhanced mechanical responses. ..
  44. AGING AND PERIOPERATIVE OUTCOMES
    JACQUELINE LEUNG; Fiscal Year: 2005
    ..versus general anesthesia after controlling for intraoperative anesthetic and hemodynamic management and postoperative pain management...
  45. PAIN AND THE DEFENSE RESPONSE
    C Chapman; Fiscal Year: 2006
    ..abstract_text> ..
  46. TMS in the Management of Postoperative Pain
    Jeffrey J Borckardt; Fiscal Year: 2010
    ..Despite profound advances in neuroscience, opiate narcotics are heavily relied upon for postoperative pain control...
  47. Genetics of Opioid Induced Hyperalgesia
    David Clark; Fiscal Year: 2004
    ..Thus our overall goal is to bring a unique and complimentary approach to the ongoing studies of OIH by using genomics to objectively identify genes involved in this phenomenon. ..
  48. Rehabilitation of Spinal Cord Injury-Related Pain
    Mark Jensen; Fiscal Year: 2006
    ..abstract_text> ..
  49. Sensory Re-training following Orthognathic Surgery
    Ceib Phillips; Fiscal Year: 2005
    ..Our primary focus will be on the patient's perception of the negative impact of altered sensation on daily life. ..
  50. Clinical and Molecular Evaluation of Cancer Therapy Induced Mucositis
    Sharon Gordon; Fiscal Year: 2007
    ..Demonstration of safety and tolerability will provide a basis to test further this route of administration. Hence, this proposal holds promise for clinical application in a relatively short period. [unreadable] [unreadable]..
  51. Catastrophizing and Pain in Rheumatoid Arthritis
    Robert Edwards; Fiscal Year: 2008
    ..abstract_text> ..
  52. PERIOPERATIVE PAIN, IMMUNE FUNCTION, AND METASTASIS
    Gayle Page; Fiscal Year: 2001
    ....
  53. Effectiveness of TENS on Hyperalgesia, Pain with Movement, and Function After TKR
    Barbara Rakel; Fiscal Year: 2010
    ..By improving functional status, older adults can retain independence and possibly reduce their health care utilization and costs. ..
  54. Improving Measurement of Acute Pain
    C Chapman; Fiscal Year: 2009
    ..The results of this work will facilitate pain research, improve the management of acute pain, and help identify patients with acute pain who are at risk for developing chronic pain. ..
  55. Role of the Amygdala in Opioid Self-administration in Rats with Chronic Pain.
    Thomas Martin; Fiscal Year: 2009
    ....
  56. Persistent Mechanical Hypersensitivity in Rats: Biobehavioral Effects
    Gayle Page; Fiscal Year: 2009
    ..The relevance of the proposed study to human health is the goal to discern what factors (e.g., sleep disruption, biological responses to stress and anxiety) increase one s risk to develop chronic pain. ..
  57. Presurgery Hypnosis in Breast Cancer: Benefits Analysis
    Guy Montgomery; Fiscal Year: 2006
    ..Mediators and moderators (e.g., hypnotizability) of hypnosis effects will be determined, as well as long-term side benefits of the intervention. ..
  58. Presurgery Hypnosis--Benefits Analysis in Breast Cancer
    Guy Montgomery; Fiscal Year: 2003
    ..The possible mediational role of these factors in hypnosis effects will be examined will classic statistical approaches. ..