post dural puncture headache

Summary

Alias: headache
Summary: The symptom of PAIN in the cranial region. It may be an isolated benign occurrence or manifestation of a wide variety of HEADACHE DISORDERS.

Top Publications

  1. doi Economic burden of transformed migraine: results from the American Migraine Prevalence and Prevention (AMPP) Study
    Julie Munakata
    IMS Consulting, Falls Church, VA 22046, USA
    Headache 49:498-508. 2009
  2. ncbi The global burden of headache: a documentation of headache prevalence and disability worldwide
    Lj Stovner
    Norwegian National Headache Centre, Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
    Cephalalgia 27:193-210. 2007
  3. doi The burden of headache in Russia: validation of the diagnostic questionnaire in a population-based sample
    I Ayzenberg
    Department of Neurology, University of Bochum, Bochum, Germany
    Eur J Neurol 18:454-9. 2011
  4. doi Prevalence of headache and migraine in children and adolescents: a systematic review of population-based studies
    Ishaq Abu-Arafeh
    Fraser of Allander Neurosciences Unit, Royal Hospital for Sick Children, Glasgow, UK
    Dev Med Child Neurol 52:1088-97. 2010
  5. ncbi The relationship between headaches and sleep disturbances
    T Paiva
    EEG and Sleep Laboratory, Centro de Estudos Egas Moniz, Neurology, Hospital Santa Maria, Lisboa, Portugal
    Headache 35:590-6. 1995
  6. ncbi Chronic daily headache in Taipei, Taiwan: prevalence, follow-up and outcome predictors
    S R Lu
    Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
    Cephalalgia 21:980-6. 2001
  7. ncbi Efficacy of multidisciplinary treatment in a tertiary referral headache centre
    P Zeeberg
    Danish Headache Centre, Department of Neurology, University of Copenhagen, Glostrup Hospital, Glostrup, Denmark
    Cephalalgia 25:1159-67. 2005
  8. doi Effectiveness of an educational and physical programme in reducing headache, neck and shoulder pain: a workplace controlled trial
    F Mongini
    Department of Clinical Pathophysiology, Headache and Facial Pain Unit, University of Turin, Turin, Italy
    Cephalalgia 28:541-52. 2008
  9. pmc Clinical outcome of a headache-specific multidisciplinary treatment program and adherence to treatment recommendations in a tertiary headache center: an observational study
    Charly Gaul
    Headache Center, Department of Neurology, University Hospital Essen, University Duisburg Essen, Hufelandstrase 55, 45147 Essen, Germany
    J Headache Pain 12:475-83. 2011
  10. ncbi Benign cough headache
    C J Boes
    Headache Group, Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK
    Cephalalgia 22:772-9. 2002

Research Grants

  1. Sharona E Gordon; Fiscal Year: 2016
  2. Abdominal Symptom Phenotypes: Pathways to New Biomarkers
    Robert Shulman; Fiscal Year: 2010
  3. Developing Novel Dual CRF-R1/Orexin-1 Receptor Antagonists for Tobacco Dependence
    Belew Mekonnen; Fiscal Year: 2011
  4. Role of TRP Channels in Environmental Irritant-Induced Headache
    Gerry S Oxford; Fiscal Year: 2013
  5. Hypothalamic Deep Brain Stimulation for Morbid Obesity:Development of a Pig Model
    William P Melega; Fiscal Year: 2010
  6. Abdu F Azad; Fiscal Year: 2016
  7. Michael J Falvo; Fiscal Year: 2014
  8. The role of stress and mast cells in a preclinical mouse model of migraine
    ANN CHRISTINE RADDANT; Fiscal Year: 2013
  9. Low-cost handheld medical device for neuroaxial anesthesia guidance in the obese
    FRANK WILLIAM MAULDIN; Fiscal Year: 2012
  10. Hongbo R Luo; Fiscal Year: 2016

Detail Information

Publications362 found, 100 shown here

  1. doi Economic burden of transformed migraine: results from the American Migraine Prevalence and Prevention (AMPP) Study
    Julie Munakata
    IMS Consulting, Falls Church, VA 22046, USA
    Headache 49:498-508. 2009
    ..To evaluate the impact of incident transformed migraine on health care resource utilization, medication use, and productivity loss. In addition, the study estimates the total direct and indirect costs associated with transformed migraine...
  2. ncbi The global burden of headache: a documentation of headache prevalence and disability worldwide
    Lj Stovner
    Norwegian National Headache Centre, Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
    Cephalalgia 27:193-210. 2007
    This study, which is a part of the initiative 'Lifting The Burden: The Global Campaign to Reduce the Burden of Headache Worldwide', assesses and presents all existing evidence of the world prevalence and burden of headache disorders...
  3. doi The burden of headache in Russia: validation of the diagnostic questionnaire in a population-based sample
    I Ayzenberg
    Department of Neurology, University of Bochum, Bochum, Germany
    Eur J Neurol 18:454-9. 2011
    We report validation of the Russian-language version of the Lifting The Burden headache screening and diagnostic questionnaire in a population-based sample of 501 individuals in four cities (Smolensk, Tchelyabinsk, Nishny Novgorod and ..
  4. doi Prevalence of headache and migraine in children and adolescents: a systematic review of population-based studies
    Ishaq Abu-Arafeh
    Fraser of Allander Neurosciences Unit, Royal Hospital for Sick Children, Glasgow, UK
    Dev Med Child Neurol 52:1088-97. 2010
    the aim of this study was to review systematically the prevalence of headache and migraine in children and adolescents and to study the influence of sex, age, and region of residence on the epidemiology.
  5. ncbi The relationship between headaches and sleep disturbances
    T Paiva
    EEG and Sleep Laboratory, Centro de Estudos Egas Moniz, Neurology, Hospital Santa Maria, Lisboa, Portugal
    Headache 35:590-6. 1995
    ..We studied 25 patients presenting with morning or nocturnal headaches. Standard headache diagnosis and polysomnography were performed. After polysomnography, the diagnoses were reevaluated...
  6. ncbi Chronic daily headache in Taipei, Taiwan: prevalence, follow-up and outcome predictors
    S R Lu
    Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan
    Cephalalgia 21:980-6. 2001
    We conducted a two-stage population-based headache survey among subjects aged > or = 15 in Taipei, Taiwan. Subjects with chronic daily headache (CDH) in the past year were identified, interviewed and followed-up...
  7. ncbi Efficacy of multidisciplinary treatment in a tertiary referral headache centre
    P Zeeberg
    Danish Headache Centre, Department of Neurology, University of Copenhagen, Glostrup Hospital, Glostrup, Denmark
    Cephalalgia 25:1159-67. 2005
    Despite the high prevalence of headaches, multidisciplinary headache clinics are few and their efficacy still needs validation...
  8. doi Effectiveness of an educational and physical programme in reducing headache, neck and shoulder pain: a workplace controlled trial
    F Mongini
    Department of Clinical Pathophysiology, Headache and Facial Pain Unit, University of Turin, Turin, Italy
    Cephalalgia 28:541-52. 2008
    ..controlled trial to evaluate the effectiveness of a workplace educational and physical programme in reducing headache and neck and shoulder pain...
  9. pmc Clinical outcome of a headache-specific multidisciplinary treatment program and adherence to treatment recommendations in a tertiary headache center: an observational study
    Charly Gaul
    Headache Center, Department of Neurology, University Hospital Essen, University Duisburg Essen, Hufelandstrase 55, 45147 Essen, Germany
    J Headache Pain 12:475-83. 2011
    This study investigated the outcome of a 5-day headache-specific multidisciplinary treatment program (MTP) and the adherence to treatment recommendations in 295 prospectively recruited consecutive headache patients [210 migraine, 17 ..
  10. ncbi Benign cough headache
    C J Boes
    Headache Group, Institute of Neurology, National Hospital for Neurology and Neurosurgery, London, UK
    Cephalalgia 22:772-9. 2002
    Benign cough headache is an uncommon primary headache disorder marked by short-lasting attacks of pain triggered by coughing. Magnetic resonance imaging of the brain is required to assure that the cough headache is truly benign...
  11. doi Peri-ictal and inter-ictal headache in children and adolescents with idiopathic epilepsy: a multicenter cross-sectional study
    Alberto Verrotti
    Department of Pediatrics, University of Chieti, Italy
    Childs Nerv Syst 27:1419-23. 2011
    b>Headache in epileptic population ranges from 8% to 15%. The aim of this paper was to study the clinical and temporal characteristics of primary headache comorbidity in idiopathic epileptic children.
  12. ncbi Headache and temporomandibular disorders: evidence for diagnostic and behavioural overlap
    A G Glaros
    Kansas City University of Medicine and Biosciences, Kansas City, MO 64106, USA
    Cephalalgia 27:542-9. 2007
    To assess the diagnostic and behavioural overlap of headache patients with temporomandibular disorders (TMD), individuals recruited from the general population with self-described headaches were compared with non-headache controls...
  13. ncbi Anxiety and psychosocial stress as predictors of headache and abdominal pain in urban early adolescents
    Kamila S White
    Department of Psychology, University of Missouri Saint Louis, 63121 4499, USA
    J Pediatr Psychol 31:582-96. 2006
    To examine the relations among anxiety, psychosocial stress, and headache and abdominal pain complaints within the context of the Biobehavioral Model of Pediatric Pain.
  14. ncbi The Sinus, Allergy and Migraine Study (SAMS)
    Eric Eross
    Scottsdale Headache Center at Arizona Neurological Institute, Scottsdale, AZ 85255, USA
    Headache 47:213-24. 2007
    The objective of this study is to classify (according to the current International Headache Society's criteria [ICHD-II]) the headache types that those with self-diagnosed sinus headache experience and to determine barriers to correct ..
  15. ncbi Biopsychosocial correlates of headache: what predicts pediatric headache occurrence?
    Birgit Kröner-Herwig
    Georg Elias Müller Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Gottingen, Gottingen, Germany
    Headache 48:529-44. 2008
    The study aims at identifying biopsychosocial risk factors for headache in children and adolescents aged 9 to 14.
  16. doi Effectiveness of an intensive multidisciplinary headache treatment program
    Birgit Gunreben-Stempfle
    The Pain Center, University of Erlangen Nuremberg, Krankenhausstrasse 12, Erlangen D 91054, Germany
    Headache 49:990-1000. 2009
    To investigate if the effectiveness of a 96-hour multidisciplinary headache treatment program exceeds the effectiveness of a 20-hour program and primary care.
  17. pmc Weather and air pollution as triggers of severe headaches
    Kenneth J Mukamal
    Department of Medicine, Beth Israel Deaconess Medical Center, Boston, MA 02215, USA
    Neurology 72:922-7. 2009
    The roles of weather conditions and air pollution as triggers of headache have been inconsistent in previous, generally small studies.
  18. doi Physical activity and headache: results from the Nord-Trøndelag Health Study (HUNT)
    E Varkey
    Cephalea Headache Centre, Gothenburg, Sweden
    Cephalalgia 28:1292-7. 2008
    ..and a cross-sectional design, the relationship between level of physical activity and migraine and non-migraine headache. In the prospective part, 22,397 participants, not likely to have headache, answered questions about physical ..
  19. ncbi Somatic complaints and psychopathology in children and adolescents: stomach aches, musculoskeletal pains, and headaches
    H L Egger
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC 27710, USA
    J Am Acad Child Adolesc Psychiatry 38:852-60. 1999
    ....
  20. ncbi Adverse effects and benefits of two years of anagrelide treatment for thrombocythemia in chronic myeloproliferative disorders
    Gunnar Birgegard
    Dept Int Medicine, University Hospital, Uppsala, Sweden
    Haematologica 89:520-7. 2004
    ..This prospective study investigated clinical toxicity and efficacy of anagrelide during two years of treatment...
  21. doi Scheduled short-term prevention with frovatriptan for migraine occurring exclusively in association with menstruation
    Stephen D Silberstein
    Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA
    Headache 49:1283-97. 2009
    ....
  22. ncbi Cervicogenic headache: diagnostic criteria
    O Sjaastad
    Dept. of Neurology, Trondheim University Hospital, Norway
    Headache 30:725-6. 1990
    Criteria for the diagnosis of cervicogenic headache are proposed, which include unilateral head pain, symptoms and signs of neck involvement, non-clustering episodic moderate pain originating in the neck then spreading to the head, and ..
  23. doi Risk factors for headache chronification
    Ann I Scher
    Uniformed Services University Preventive Medicine Biometrics, Bethesda, MD 20814, USA
    Headache 48:16-25. 2008
    ..While there is uncertainty about the biological mechanisms that lead to headache "chronification," the epidemiologic literature has provided some insight into modifiable and nonmodifiable ..
  24. ncbi The associations among childhood headaches, emotional and behavioral difficulties, and health care use
    Tara W Strine
    Centers for Disease Control and Prevention, Atlanta, GA 30341, USA
    Pediatrics 117:1728-35. 2006
    ..They contribute to missed school days, affect children's peer and family relationships, and significantly impact children's quality of life, often times into adulthood...
  25. ncbi Headache and sleep
    Andrea Alberti
    Sleep Laboratory, Neurologic Clinic of Perugia, Via E dal Pozzo, 06126 Perugia, Italy
    Sleep Med Rev 10:431-7. 2006
    b>Headache and sleep have long been recognised as being interdependent due to specific causative factors. Yet, the precise understanding of the roles played by these factors in this interdependency remains elusive...
  26. ncbi Psychiatric comorbidity in chronic daily headache: pathophysiology, etiology, and diagnosis
    Vincenzo Guidetti
    Department of Child and Adolescent Neurology and Psychiatry, Interuniversity Center for the Study of Headache and Neurotransmitter Disorders Section of Rome, University of Rome La Sapienza, Via dei Sabelli 108, Italy
    Curr Pain Headache Rep 6:492-7. 2002
    Chronic daily headache is a challenge for clinical practitioners and researchers. Etiology, pathophysiology, diagnosis, treatment, and prognosis of chronic daily headache present many questions that need answers...
  27. ncbi Chronic frequent headache in the general population: prevalence and associated factors
    N J Wiendels
    Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands
    Cephalalgia 26:1434-42. 2006
    We studied the prevalence and short-term natural course of chronic frequent headache (CFH) in the general population and identified risk factors. In the Netherlands everyone is registered at a single general practice...
  28. ncbi Stimulation of the greater occipital nerve induces increased central excitability of dural afferent input
    Thorsten Bartsch
    Headache Group, Institute of Neurology, London, UK
    Brain 125:1496-509. 2002
    ..This mechanism may be important in pain referral from cervical structures to the head and therefore have implications for most forms of primary headache.
  29. ncbi Comorbidity of migraine and depression: investigating potential etiology and prognosis
    N Breslau
    Department of Psychiatry, Henry Ford Health System, Detroit, MI 48202 3450, USA
    Neurology 60:1308-12. 2003
    ..An association between migraine and major depression has been observed in clinical and community samples. The factors that contribute to this association and their implications remain unclear...
  30. doi Migraine: where and how does the pain originate?
    Karl Messlinger
    Institute of Physiology and Pathophysiology, University of Erlangen Nurnberg, Erlangen, Germany
    Exp Brain Res 196:179-93. 2009
    Migraine is a complex neurological disease with a genetic background. Headache is the most prominent and clinically important symptom of migraine but its origin is still enigmatic...
  31. doi Attention in children and adolescents with headache
    Daria Riva
    Developmental Neurology Division, Fondazione IRCCS Istituto Neurologico C Besta, Milano, Italy
    Headache 52:374-84. 2012
    ..studies reporting consistent visual reaction times slowing in patients with migraine prompted us to verify if headache could be associated to a broader impairment of attention...
  32. pmc Influence of headache frequency on clinical signs and symptoms of TMD in subjects with temple headache and TMD pain
    Gary C Anderson
    University of Minnesota School of Dentistry, Department of Developmental and Surgical Sciences, Minneapolis, MN 55455, USA
    Pain 152:765-71. 2011
    The relationship of the frequency of temple headache to signs and symptoms of temporomandibular joint (TMJ) disorders (TMD) was investigated in a subset of a larger convenience sample of community TMD cases...
  33. ncbi High altitude headache. A prospective study of its clinical characteristics
    M Serrano-Dueñas
    Movement Disorders Clinic, Neurological Service, Hospital Carlos Andrade Marín and, Medicine Faculty, Pontificia Universidad Catolica del Ecuador, Quito, Ecuador
    Cephalalgia 25:1110-6. 2005
    Altitude headache (AH) is the most common symptom of high altitude exposure. This prospective cross-sectional and analytical study, conducted in the Ecuadorian Andes, aimed to explore AH symptomatology, taking into account subjects' views...
  34. doi Medication use in patients with migraine and medication-overuse headache: the role of problem-solving and attitudes about pain medication
    Emelien Lauwerier
    Department of Experimental Clinical and Health Psychology, Ghent University, Ghent, Belgium
    Pain 152:1334-9. 2011
    Excessive medication intake is a risk factor for the development of medication-overuse headache (MOH), a condition characterized by an increase of headache frequency to a daily or near-daily pattern...
  35. ncbi Migraine can be induced by sildenafil without changes in middle cerebral artery diameter
    Christina Kruuse
    Department of Neurology, Glostrup Hospital, University of Copenhagen, Glostrup, Copenhagen, Denmark
    Brain 126:241-7. 2003
    ..Radial and temporal artery diameters were studied using high-frequency ultrasonography. Headache response, tenderness of pericranial muscles, blood pressure and heart rate were measured repeatedly...
  36. ncbi The burden of headache in a patient population from a specialized headache centre
    G R Vinding
    Danish Headache Centre, Department of Neurology, University of Copenhagen, Glostrup Hospital, Glostrup, Denmark
    Cephalalgia 27:263-70. 2007
    The aim was to characterize the individual and socio-economic impact of headache in a patient population from The Danish Headache Centre...
  37. doi Are headache and temporomandibular disorders related? A blinded study
    V Ballegaard
    Danish Headache Centre and Department of Neurology, University of Copenhagen, Glostrup Hospital, Glostrup, Denmark
    Cephalalgia 28:832-41. 2008
    To investigate overlaps between headache and temporomandibular disorders (TMD) in a clinical headache population and to describe the prevalence of TMD in headache patients, 99 patients referred to a specialized headache centre were ..
  38. ncbi Clinical features and prognostic factors in adults with bacterial meningitis
    Diederik van de Beek
    Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    N Engl J Med 351:1849-59. 2004
    ..We conducted a nationwide study in the Netherlands to determine clinical features and prognostic factors in adults with community-acquired acute bacterial meningitis...
  39. ncbi Mood and anxiety disorders in chronic headache
    Steven M Baskin
    New England Institute for Behavioral Medicine, Stamford, CT 06902, USA
    Headache 46:S76-87. 2006
    Although most individuals with recurrent headache disorders in the general population do not experience severe psychopathology, population-based studies and clinical investigations find high rates of comorbidity between headache and mood ..
  40. pmc Headache associated with pituitary tumors
    Jackson A Gondim
    Neurosurgery Division of Neurosurgery Department, General Hospital of Fortaleza HGF, CE, Brazil
    J Headache Pain 10:15-20. 2009
    The objective of this study is to analyze the presence of headache in pituitary tumors and their characteristics, the relationship between pituitary tumor size, biological type, local extension and intrasellar pressure (ISP)...
  41. doi Pediatric headache: a clinical review
    Howard Jacobs
    University of Maryland, Department of Pediatrics, Pediatric Headache Clinic, Baltimore, MD, USA
    Headache 52:333-9. 2012
    ..We review both traditional and alternative medications, and offer a glimpse into the future of pediatric headache.
  42. doi Sleep and headache
    K C Brennan
    Headache Research and Treatment Program, Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California 90095, USA
    Semin Neurol 29:406-18. 2009
    There is a strong interaction between sleep and headache. Sleep and headache disorders overlap epidemiologically, and share elements of anatomy and physiology. Perhaps as a result, their treatment is often mutually interdependent...
  43. doi Headache attributed to intracranial tumours: a prospective cohort study
    L Valentinis
    Department of Neurology, Santa Maria della Misericordia University Hospital, Udine, Italy
    Cephalalgia 30:389-98. 2010
    ..Preoperatively, all patients were interviewed by a neurologist to collect headache characteristics...
  44. doi Lack of correlation between vasodilatation and pharmacologically induced immediate headache in healthy subjects
    Messoud Ashina
    Danish Headache Center and Department of Neurology, Glostrup Hospital, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    Cephalalgia 31:683-90. 2011
    The causal relationship between experimental headache and vasodilatation has not been fully clarified...
  45. doi Headache in patients with a meningioma correlates with a bone-invasive growth pattern but not with cytokine expression
    C J Schankin
    Department of Neurology, University of Munich Hospital Großhadern, Munich, Germany
    Cephalalgia 30:413-24. 2010
    ..in a prospective study to analyse the prevalence of and risk factors for different types of meningioma-associated headache. Twenty-three patients (40%) had meningioma-associated headache...
  46. ncbi Patterns and predictors of prescription medication use in the management of headache: findings from the 2000 Medical Expenditure Panel Survey
    Joshua W Devine
    Social and Administrative Graduate Program, College of Pharmacy, University of Minnesota, MN 55455, USA
    Headache 45:1171-80. 2005
    The primary objectives were to examine national trends of prescription medication use for headache and explore patterns of variation in the use of these medications across social and demographic levels.
  47. ncbi Indomethacin responsive headache syndromes: chronic paroxysmal hemicrania and Hemicrania continua. How they were discovered and what we have learned since
    O Sjaastad
    Department of Neurology, St Olavs Hospital, Trondheim University Hospital, Trondheim, Norway
    Funct Neurol 25:49-55. 2010
    ..Traditionally, CPH has been linked to cluster headache (CH) due to clinical similarities: unilaterality, intensity, and some autonomic phenomena...
  48. doi An electronic daily diary process study of stress and health behavior triggers of primary headaches in children
    Mark Connelly
    Integrative Pain Management, Developmental and Behavioral Sciences, Children s Mercy Hospitals and Clinics, 2401 Gillham Road, Kansas City, MO 64108, USA
    J Pediatr Psychol 36:852-62. 2011
    To determine through a daily process study whether alleged psychological and health behavior headache triggers reliably predict headache occurrence in children.
  49. doi Phenotype of patients responsive to occipital nerve stimulation for refractory head pain
    K Paemeleire
    Department of Neurology, Ghent University Hospital, Ghent, Belgium
    Cephalalgia 30:662-73. 2010
    ..Identification of specific headache diagnoses responding to this modality of treatment is required...
  50. ncbi Characteristics of brain tumour-associated headache
    C J Schankin
    Neurologische Klinik und Poliklinik, Kilinikum der Universität München, Grosshadern, Munchen, Germany
    Cephalalgia 27:904-11. 2007
    Eighty-five brain tumour patients were examined for further characteristics of brain tumour-associated headache. The overall prevalence of headache in this population was 60%, but headache was the sole symptom in only 2%...
  51. ncbi Hormone-related headache: pathophysiology and treatment
    Avi Ashkenazi
    Department of Neurology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA
    CNS Drugs 20:125-41. 2006
    ..type or the route of administration of hormone replacement therapy (HRT) from oral to transdermal may reduce headache. Migraine is not a risk factor for stroke in postmenopausal women...
  52. doi Headaches and sleep problems among adults in the United States: findings from the National Comorbidity Survey-Replication study
    Tarannum Lateef
    National Institute of Mental Health, USA
    Cephalalgia 31:648-53. 2011
    Several studies have demonstrated an association between headache and disturbed sleep. None have examined this association across the headache spectrum...
  53. pmc A potential nitrergic mechanism of action for indomethacin, but not of other COX inhibitors: relevance to indomethacin-sensitive headaches
    Oliver Summ
    Headache Group, Department of Neurology, University of California, 1701 Divisadero St, Suite 480, San Francisco, CA 94115, USA
    J Headache Pain 11:477-83. 2010
    ..drugs (NSAIDs) that act as cyclo-oxygenase (COX) inhibitors are commonly used in the treatment of a range of headache disorders, although their mechanism of action is unclear...
  54. ncbi Oral contraceptives and increased headache prevalence: the Head-HUNT Study
    K Aegidius
    Department of Neuroscience, Norwegian National Headache Centre, St Olav s University Hospital, Trondheim, Norway
    Neurology 66:349-53. 2006
    To examine the prevalence of headache and migraine among women using oral contraceptives (OCs) in a large, cross-sectional population-based study.
  55. ncbi Temporomandibular disorders and headache
    Steven B Graff-Radford
    Pain Center, Cedars Sinai Medical Center, 444 South San Vicente, 1101 Los Angeles, CA 90048, USA
    Dent Clin North Am 51:129-44, vi-vii. 2007
    b>Headache is a common symptom, but when severe, it may be extremely disabling. It is assumed that patients who present to dentists with headache often are diagnosed with a temporomandibular disorder (TMD), although many may have migraine...
  56. ncbi Case series of four different headache types presenting as tooth pain
    Aurelio A Alonso
    Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, Minnesota 55455, USA
    J Endod 32:1110-3. 2006
    Case reports in the literature discuss various headache disorders that present as pain in the face...
  57. doi Cerebral venous sinus thrombosis following accidental dural puncture and epidural blood patch
    S Ghatge
    Department of Anaesthesia, University Hospital of North Staffordshire, Stoke on Trent, UK
    Int J Obstet Anesth 17:267-70. 2008
    ..The epidural was complicated by an accidental dural puncture and the ensuing headache was initially treated with an epidural blood patch...
  58. ncbi Self-reported headache in schoolchildren: parents underestimate their children's headaches
    Christofer Lundqvist
    Department of Neurology, Ulleval University Hospital, Oslo, Norway
    Acta Paediatr 95:940-6. 2006
    Most previous studies of childhood headache have used indirect parental/physician reports to estimate the prevalence of headache in children.
  59. pmc Validation of a Georgian language headache questionnaire in a population-based sample
    Maka Kukava
    Department of Neurology, University Hospital Essen, University of Essen, Hufelandstr 55, DE 45122 Essen, Germany
    J Headache Pain 8:321-4. 2007
    In a pilot phase of a survey of the prevalence of primary headache disorders in the Republic of Georgia, we validated a Georgian language questionnaire for migraine (MIG), tension-type headache (TTH), MIG+TTH and trigeminal autonomic ..
  60. doi Long-term benefits of an educational and physical program on headache, and neck and shoulder pain, in a working community
    Franco Mongini
    Department of Clinical Pathophysiology, University of Turin, Italy
    J Pain 10:1138-45. 2009
    ..of a controlled trial that showed the efficacy of a workplace educational and physical program in reducing headache, and neck and shoulder pain...
  61. ncbi Headache in United States emergency departments: demographics, work-up and frequency of pathological diagnoses
    J N Goldstein
    Department of Emergency Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Cephalalgia 26:684-90. 2006
    b>Headache is a common complaint in the emergency department (ED)...
  62. ncbi Headache in German children and adolescents: a population-based epidemiological study
    B Kröner-Herwig
    Georg Elias Müller Institute of Psychology, Department of Clinical Psychology and Psychotherapy, University of Gottingen, Gottingen, Germany
    Cephalalgia 27:519-27. 2007
    The aim of the present study was to assess the distribution and characteristics of headache in children aged 7-14 years in Lower Saxony (Germany). For the survey, 8800 households with children were randomly drawn from community registers...
  63. doi Prostaglandin E2(PGE2) induces headache in healthy subjects
    T Wienecke
    Danish Headache Centre and Department of Neurology, Glostrup Hospital, Faculty of Health Sciences, University of Copenhagen, Glostrup, Copenhagen, Denmark
    Cephalalgia 29:509-19. 2009
    The role of prostanoids in nociception is well established. The headache-eliciting effects of prostaglandin E(2) (PGE(2)) and its possible mechanisms have previously not been systematically studied in man...
  64. ncbi Outdoor pollution and headache
    G Nattero
    Department of Clinical Physiopathology, Turin University, Torino, Italy
    Headache 36:243-5. 1996
    The aim of this study was to clarify a possible relationship between pollution and worsening of headache in the industrial city of Turin...
  65. ncbi Manual therapy and exercise for neck pain: a systematic review
    Jordan Miller
    School of Rehabilitation Science, McMaster University, Hamilton, Canada
    Man Ther 15:334-54. 2010
    ..of life, global perceived effect, and patient satisfaction for adults with neck pain with or without cervicogenic headache or radiculopathy. Computerized searches were performed to July 2009...
  66. ncbi Prevalence and co-occurrence of self-rated pain and perceived health in school-children: Age and gender differences
    Gunilla M Brun Sundblad
    Department of Molecular Medicine and Surgery, Section of Sports Medicine, Karolinska Institutet, M3 Building, SE 171 76 Stockholm, Sweden
    Eur J Pain 11:171-80. 2007
    ..The main aim of the study was to assess the prevalence of self-reported pain (headache, abdominal, and musculoskeletal pain) and perceived health (problems sleeping and/or if they often felt tired, ..
  67. pmc Recommendations for headache service organisation and delivery in Europe
    T J Steiner
    Department of Neuroscience, Norwegian University of Science and Technology, Trondheim, Norway
    J Headache Pain 12:419-26. 2011
    b>Headache disorders are a major public-health priority, and there is pressing need for effective solutions to them...
  68. doi Comorbidity of headache and gastrointestinal complaints. The Head-HUNT Study
    A H Aamodt
    Norwegian National Headache Centre, Trondheim University Hospital, Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology, Norway
    Cephalalgia 28:144-51. 2008
    Associations between headache, including migraine, and gastrointestinal (GI) symptoms were studied in a large questionnaire-based cross-sectional study (the Head-HUNT Study)...
  69. ncbi The red ear syndrome: an auriculo-autonomic cephalgia
    Randolph W Evans
    Headache 44:835-6. 2004
  70. pmc Psychiatric disorders and headache familial recurrence: a study on 200 children and their parents
    Federica Galli
    Department of Child and Adolescent Neurology, Psychiatry and Rehabilitation, University of Rome La Sapienza, Rome, Italy
    J Headache Pain 10:187-97. 2009
    The main aim of the study was to examine the relationship between headache and familial recurrence of psychiatric disorders in parents and their children...
  71. ncbi Occipital nerve stimulation for chronic cluster headache and hemicrania continua: pain relief and persistence of autonomic features
    T J Schwedt
    Mayo Clinic College of Medicine, Scottsdale, AZ 85259, USA
    Cephalalgia 26:1025-7. 2006
  72. ncbi Acute and interictal allodynia in patients with different headache forms: an Italian pilot study
    Carlo Lovati
    Neurology Unit, Department of Clinical Sciences L Sacco, University of Milan, Italy
    Headache 48:272-7. 2008
    ..To investigate allodynia in patients with different primary headaches...
  73. doi Hemicrania continua: a clinical study of 39 patients with diagnostic implications
    Elisabetta Cittadini
    Headache Group, Institute of Neurology, The National Hospital for Neurology and Neurosurgery, London WC1N 3BG, UK
    Brain 133:1973-86. 2010
    Hemicrania continua is an uncommon primary headache disorder, characterized by continuous unilateral pain, where pain exacerbations are associated with cranial autonomic features...
  74. ncbi Clinical features of withdrawal headache following overuse of triptans and other headache drugs
    Z Katsarava
    Department of Neurology, University Hospital Essen, Germany
    Neurology 57:1694-8. 2001
    BACKGROUND: Complete withdrawal from headache medication is the treatment of choice for medication-overuse headache...
  75. ncbi The development of a symptom questionnaire for assessing virtual reality viewing using a head-mounted display
    Shelly L Ames
    Department of Optometry and Vision Sciences, University of Melbourne, Melbourne, Victoria 3010, Australia
    Optom Vis Sci 82:168-76. 2005
    ..However, there are numerous reports that adverse effects such as ocular discomfort and headache are associated with these devices...
  76. ncbi Clinical aspects of 2541 patients with second stage human African trypanosomiasis
    Johannes Blum
    Swiss Tropical Institute, Medical and Diagnostic Services, Socinstrasse 57, 4002 Basel, Switzerland
    Acta Trop 97:55-64. 2006
    ..b>Headache (78.7%), sleeping disorder (74.4%) and lymphadenopathy (56...
  77. pmc Pain as the only symptom of cervical artery dissection
    M Arnold
    Assistance Publique, Hopitaux de Paris, Department of Neurology, University Hospital Lariboisiere, Paris, France
    J Neurol Neurosurg Psychiatry 77:1021-4. 2006
    b>Headache or neck pain is a frequent symptom of spontaneous cervical artery dissection (sCAD).
  78. ncbi Self-reported headache frequency and features associated with frequent headaches in Canadian young adolescents
    K E Gordon
    Department of Pediatrics, Dalhousie University, and IWK Health Centre, Halifax, Nova Scotia, Canada
    Headache 44:555-61. 2004
    To explore the associated factors for frequent headache among young adolescent Canadians.
  79. ncbi Comorbidity of depressive and anxiety disorders in chronic daily headache and its subtypes
    K D Juang
    Department of Psychiatry, Taipei Veterans General Hospital, Taiwan
    Headache 40:818-23. 2000
    OBJECTIVE: To investigate the frequency of depressive and anxiety disorders in patients with chronic daily headache. BACKGROUND: There is a lack of data in the literature on the extent of psychiatric comorbidity in patients with different ..
  80. doi Epidemiology and comorbidity of headache
    Rigmor Jensen
    Danish Headache Center, Department of Neurology, University of Copenhagen, Glostrup Hospital, DK 2600 Glostrup, Denmark
    Lancet Neurol 7:354-61. 2008
    The burden associated with headache is a major public health problem, the true magnitude of which has not been fully acknowledged until now...
  81. doi Ambient air pollution and daily emergency department visits for headache in Ottawa, Canada
    Mieczyslaw Szyszkowicz
    Air Health Effects Division, Health Canada, Ottawa, ON, Canada
    Headache 48:1076-81. 2008
    No extensive studies exist on the relation between ambient air pollution and health outcomes such as migraine or headache. From other side, existing publications indicated that air pollutants can trigger migraine or headache.
  82. ncbi The occurrence of recall bias in pediatric headache: a comparison of questionnaire and diary data
    M van den Brink
    Department of Health Care Sciences, Centre for Nursing Research, Maastricht University, 6200 MD Maastricht, The Netherlands
    Headache 41:11-20. 2001
    OBJECTIVE: To investigate whether children and adolescents can recall prior headache complaints accurately and to study whether age, gender, headache severity, preferred coping strategies, depression, somatization, and trait anxiety are ..
  83. ncbi A longitudinal epidemiologic study of signs and symptoms of temporomandibular disorders from 15 to 35 years of age
    T Magnusson
    Department of Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jonkoping, Sweden
    J Orofac Pain 14:310-9. 2000
    ..To study the development over 20 years of signs and symptoms of temporomandibular disorders (TMD) in an epidemiologic sample and to analyze possible correlations between these signs and symptoms and some other variables...
  84. ncbi Trigeminal cephalgias and facial pain syndromes associated with autonomic dysfunction
    A S Al-Din
    Neurosciences Department, Pinderfields General Hospital, Wakefield, UK
    Cephalalgia 25:605-11. 2005
    Trigeminal autonomic cephalgias (TACs) include a spectrum of primary headache syndromes associated with cranial autonomic dysfunction...
  85. pmc Blood pressure and risk of headache: a prospective study of 22 685 adults in Norway
    K Hagen
    Department of Clinical Neuroscience, Section of Neurology, Faculty of Medicine, Norwegian University of Science and Technology, 7006 Trondheim, Norway
    J Neurol Neurosurg Psychiatry 72:463-6. 2002
    Prevalence studies of the association between blood pressure and headache have shown conflicting results. The aim was to analyse the relation between blood pressure and risk of headache in a prospective study.
  86. ncbi Repeated measures of recent headache, neck and upper back pain in Australian adolescents
    K Grimmer
    Centre for Allied Health Evidence, University of South Australia, Adelaide, Australia
    Cephalalgia 26:843-51. 2006
    The epidemiological and clinical literature identifies strong associations between adult headache, cervical and thoracic spine dysfunction and spinal posture...
  87. doi Prevalence and burden of headache and migraine in Germany
    Andrea Radtke
    Department of Neurology, Virchow Klinikum, Charite, Berlin
    Headache 49:79-89. 2009
    To determine prevalence and burden of headache and migraine in the general population in Germany including patterns of healthcare and medication use.
  88. pmc Guidelines for the organization of headache education in Europe: the headache school II
    Rigmor Jensen
    Danish Headache Center, Department of Neurology, Glostrup Hospital, University of Copenhagen, Ndr Ringvej 69, Building 24, Glostrup, Denmark
    J Headache Pain 11:161-5. 2010
    In order to promote education on headache disorders, European Headache Federation (EHF) in conjunction with National Headache Societies organizes educational courses meeting uniform standards according to previous published guidelines...
  89. pmc Improving care through health economics analyses: cost of illness and headache
    Francesco Saverio Mennini
    CEIS Sanità Centre for Health Economics and Management CHEM, Faculty of Economics, University of Rome Tor Vergata, Rome, Italy
    J Headache Pain 9:199-206. 2008
    The impact of headache disorders is a problem of enormous proportions, both for individual and society...
  90. ncbi Frontal lobe involvement in the processing of meaningful auditory stimuli develops during childhood and adolescence
    Stephan Bender
    Department for Child and Adolescent Psychiatry, Psychiatric Hospital, University of Heidelberg, Blumenstrasse 8, D 69115 Heidelberg, Germany
    Neuroimage 33:759-73. 2006
    ..current source density mapping and spatio-temporal source analysis in 80 healthy subjects and 121 primary headache patients (migraine with/without aura, tension type headache) from 6 to 18 years; as increased orienting responses ..
  91. ncbi Classification of daily and near-daily headaches: proposed revisions to the IHS criteria
    S D Siberstein
    Comprehensive Headache Center, Germantown Hospital and Medical Center, PA
    Headache 34:1-7. 1994
    The International Headache Society (IHS) headache classification, while a major advance, does not adequately classify the daily and near-daily headache disorders known as chronic daily headache (CDH)...
  92. doi Headaches and migraines are associated with an increased risk of preeclampsia in Peruvian women
    Sixto E Sanchez
    Health Direction V Lima City Jr Antonio Raymondi 220, La Victoria, Lima, Peru
    Am J Hypertens 21:360-4. 2008
    ..We assessed the risk for preeclampsia in relation to the maternal history of migraine before and during pregnancy in Peruvian women...
  93. pmc Classification and clinical features of headache patients: an outpatient clinic study from China
    Yunfeng Wang
    Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China
    J Headache Pain 12:561-7. 2011
    This study aimed to analyze and classify the clinical features of headache in neurological outpatients...
  94. doi Prevalence of chronic migraine and medication overuse headache in Germany--the German DMKG headache study
    A Straube
    Department of Neurology, Klinikum Großhadern Ludwig Maximilians University Munich, Germany
    Cephalalgia 30:207-13. 2010
    Population-based epidemiological studies about the prevalence of chronic migraine using the 2004 International Headache Society (IHS) classification definition are rare...
  95. pmc Idiopathic intracranial hypertension
    Michael Wall
    Department of Neurology, College of Medicine, University of Iowa, Veterans Administration Medical Center, Iowa City, IA 52242, USA
    Neurol Clin 28:593-617. 2010
    ..Although there are no evidence-based data to guide therapy, there is an ongoing randomized double-blind controlled treatment trial of IIH investigating diet and medical therapy...
  96. ncbi Recurrent pain symptoms in young schoolchildren are often multiple
    Solveig Petersen
    Department of Clinical Sciences, Paediatrics, Umea University, Umea, Sweden
    Pain 121:145-50. 2006
    ..The present study investigated frequency and co-occurrence of recurrent headache, stomach-ache, and backache in young schoolchildren (6-13 years of age)...
  97. pmc A survey of visually induced symptoms and associated factors in spectators of three dimensional stereoscopic movies
    Angelo G Solimini
    Department of Public Health and Infectious Diseases, Sapienza University of Rome, Piazza Aldo Moro, 5, 00185, Rome, Italy
    BMC Public Health 12:779. 2012
    ..This study aims to (1) quantify the occurrence of visually induced symptoms suffered by the spectators during and after viewing a commercial 3D movie and (2) to assess individual and environmental factors associated to those symptoms...
  98. pmc Holding on to the indispensable medication--a grounded theory on medication use from the perspective of persons with medication overuse headache
    Pernilla Jonsson
    Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, PO Box 453SE 40530, Gothenburg, Sweden
    J Headache Pain 14:43. 2013
    Medication overuse headache (MOH) is a chronic headache disorder, caused by overuse of acute medication. To date, it remains unclear why some people overuse these medications...
  99. ncbi Reconsidering the effects of monosodium glutamate: a literature review
    Matthew Freeman
    OhioHealth, Columbus, Ohio, USA
    J Am Acad Nurse Pract 18:482-6. 2006
    ..from the past 40 years of research related to monosodium glutamate (MSG) and its ability to trigger a migraine headache, induce an asthma exacerbation, or evoke a constellation of symptoms described as the "Chinese restaurant ..
  100. ncbi Review of sulfonamide-induced acute myopia and acute bilateral angle-closure glaucoma
    Vasudha A Panday
    Wilford Hall Medical Center, San Antonio, TX, USA
    Compr Ophthalmol Update 8:271-6. 2007
    ..involvement with blurring of vision that generally occurs over minutes to hours, nausea or vomiting, red eye, and headache. Examination may show conjunctival injection, corneal edema, anterior chamber inflammation, and flat or shallow ..
  101. ncbi A six-item short-form survey for measuring headache impact: the HIT-6
    M Kosinski
    QualityMetric Incorporated Lincoln, RI 02865, USA
    Qual Life Res 12:963-74. 2003
    ..Migraine and other severe headaches can cause suffering and reduce functioning and productivity. Patients are the best source of information about such impact...

Research Grants83

  1. Sharona E Gordon; Fiscal Year: 2016
    ..b>Headache, back pain, arthritis pain, tooth pain, cancer pain, and post-operative pain are just a few of the common ..
  2. Abdominal Symptom Phenotypes: Pathways to New Biomarkers
    Robert Shulman; Fiscal Year: 2010
    ..There are well-recognized associations between IBS and other conditions (fibromyalgia, headache) and symptoms (depression, fatigue, insomnia)...
  3. Developing Novel Dual CRF-R1/Orexin-1 Receptor Antagonists for Tobacco Dependence
    Belew Mekonnen; Fiscal Year: 2011
    ..and is further confounded by serious unwanted side effects such as insomnia, dry mouth, seizure, nausea, headache, psychotropic and gastrointestinal upset...
  4. Role of TRP Channels in Environmental Irritant-Induced Headache
    Gerry S Oxford; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Headache is one of the most frequent complaints attributed to environmental air pollution (indoor and outdoor), but the total impact on public health is difficult to quantify...
  5. Hypothalamic Deep Brain Stimulation for Morbid Obesity:Development of a Pig Model
    William P Melega; Fiscal Year: 2010
    ..g., Parkinson's disease, epilepsy, cluster headache)...
  6. Abdu F Azad; Fiscal Year: 2016
    ..The illness is accompanied by fever, headache, chills, vomiting, nausea, myalgia, and rash and leads to disseminated multisystem disease...
  7. Michael J Falvo; Fiscal Year: 2014
    ..or disease also present with a heterogeneous mix of symptoms that include exercise intolerance, fatigue, headache, and general weakness - symptoms shared with GWI...
  8. The role of stress and mast cells in a preclinical mouse model of migraine
    ANN CHRISTINE RADDANT; Fiscal Year: 2013
    ..Additionally, it will provide some insight into the mechanism of how stress precipitates migraine. Overall, this project will assess the first evidence of a physiological trigger of a migraine symptom in an animal model. ..
  9. Low-cost handheld medical device for neuroaxial anesthesia guidance in the obese
    FRANK WILLIAM MAULDIN; Fiscal Year: 2012
    ..As a result, procedure failures occur at high rates (i.e. 40% - 80%) resulting in numerous health complications: headache, hematoma, backpain, vascular puncture, pleural puncture, pneumothorax, and paralysis...
  10. Hongbo R Luo; Fiscal Year: 2016
    ..respond to antibiotic treatment and G-CSF therapy is often associated with side-effects such as bone pain, headache, fatigue, nausea, and higher risk of getting leukemia...
  11. 7th National Headache Foundation Research Summit
    Rima Dafer; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): This proposal details an application to support the 7th Headache Research Summit of the National Headache Foundation, which will be an educational seminar that is planned in conjunction with the ..
  12. NEURONAL CONTROL OF CGRP GENE EXPRESSION
    ANDREW RUSSO; Fiscal Year: 2009
    Calcitonin gene-related peptide (CGRP) has been implicated in craniofacial pain and headache by virtue of its expression in the trigeminal ganglion and roles in neurogenic inflammation and nociception...
  13. Gregory O Dussor; Fiscal Year: 2015
    DESCRIPTION (provided by applicant): Migraine headache was once thought to be predominately of vascular origin but it is now increasingly appreciated that its genesis and progression also involves maladaptive changes in the nervous ..
  14. The Prevalence of Blood Pressure Abnormalities among Veterans with SCI
    Jill Wecht; Fiscal Year: 2009
    ..by a noxious or non-noxious stimulus below the level of SCI and often presents with symptoms including pounding headache, pallor, pilomotor erection, increased spasticity and flushing of the head and neck (1, 6, 9);although '..
  15. MODULATION OF MIGRAINE CIRCUIT BY SEROTONIN 1D RECEPTOR-ASSOCIATED PROTEINS
    Yuqing Cao; Fiscal Year: 2013
    ..Current treatments for migraine headache often fall short...
  16. Immune cell dynamics during central nervous system viral infection
    Juan C de la Torre; Fiscal Year: 2010
    ..by a long list of human pathogens, including viruses, and is often associated with symptoms that include fever, headache, stiffness of the neck, and seizures...
  17. Inflammatory Response in Influenza Virus Infection
    Thomas M Moran; Fiscal Year: 2010
    ..virus infection causes yearly infections characterized by the abrupt onset of symptoms including fever, myalgia, headache, malaise and chills...
  18. FUNCTIONAL ANALYSIS OF CALCIUM CHANNEL MUTATIONS IN TRIGEMINAL NOCICEPTION
    Yuqing Cao; Fiscal Year: 2010
    ..mutation, on voltage-dependent Ca2+ influx in neurons from the trigeminal nociceptive pathway responsible for headache pain generation...
  19. Frank Porreca; Fiscal Year: 2014
    ..drugs which are effective in some patients but which are also associated with an increase in the incidence of headache frequency, i.e., medication overuse headache...
  20. Solutions for Vertigo presentations in the Emergency Department (SOLVE) Project
    KEVIN ANTHONY KERBER; Fiscal Year: 2012
    ..Dizziness presentations are different from other common diagnostic dilemmas (e.g., chest pain and headache presentations) because no laboratory, electrophysiological, or neuro-imaging test is a valid and practical ..
  21. T Rajendra Kumar; Fiscal Year: 2016
    ..such as damage to brain tissue and optic chiasm, vision loss, increased intracranial pressure, persistent headache and nausea...
  22. Marilyn J Cipolla; Fiscal Year: 2016
    ..of pregnancy that occurs when hypertension during pregnancy develops with neurologic complications, including headache, vomiting, blindness and convulsions...
  23. Mitchell W Mutz; Fiscal Year: 2014
    ..CM presents with symptoms including severe nausea, headache due to inflammation of the meninges, altered mental status, and fever...
  24. Kwoon Y Wong; Fiscal Year: 2016
    ..such as occurs in shift workers or the blind, can lead to "jet lag" symptoms, winter depression, sleep disorders, headache, and even breast and prostate cancer...
  25. Evaluation of Salmonella in Symptomatic and Asymptomatic Pets
    Timothy S Frana; Fiscal Year: 2012
    ..Symptoms in people include nausea, vomiting, abdominal cramps, diarrhea, fever and headache. Animals may also show signs of gastrointestinal disease, although they may harbor Salmonella bacteria without ..
  26. Rami Burstein; Fiscal Year: 2014
    ..About 85% of people experiencing a migraine attack seek sanctuary in a dark environment in order to lessen headache intensification brought on by ambient light. The neural mechanism of this photophobic reaction remains a puzzle...
  27. Comorbid Chronic Pain Conditions - Mechanisms, Diagnosis and Treatments
    Allen W Cowley; Fiscal Year: 2011
    ..They include: chronic fatigue syndrome, chronic headache, endometriosis, fibromyalgia, irritable bowel syndrome, interstitial cystitis, and vulvodynia...
  28. Augen A Pioszak; Fiscal Year: 2016
    ..CLR-RAMP complexes have the potential to treat acute myocardial infarction, pulmonary hypertension, migraine headache, cancer, and several other disorders. CTR-RAMP complexes are targets of the diabetes drug SymlinTM...
  29. MICHAEL GORDON HARRINGTON; Fiscal Year: 2015
    DESCRIPTION (provided by applicant): Migraine is a severely disabling headache disorder for which treatment is ineffective for millions of Americans, because individuals have no reliable way to predict drug responses or side effects...
  30. Drug & Non-Drug Treatment of Pediatric Chronic Headache
    Scott Powers; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Chronic daily headache (CDH;defined as 15 or more headache days per month) is a chronic pain condition associated with a great deal of pain, suffering and disability...
  31. BRIAN CHRISTOPHER JACKSON; Fiscal Year: 2014
    ..cellular dysfunction at the molecular level, and acetaldehyde accumulation causes facial flushing, tachycardia, headache and nausea, and alcohol avoidance at the physiological level...
  32. Activation of the Trigeminovascular Pathway
    Rami Burstein; Fiscal Year: 2011
    ..Migraine is a unilateral throbbing headache usually heralded by visual aura, as well as other premonitory symptoms, beginning several minutes earlier...
  33. An ontology for pain and related disability, mental health and quality of life.
    WERNER M CEUSTERS; Fiscal Year: 2012
    ..datasets that broadly encompass the major types of pain (orofacial pains, temporomandibular disorder pain, headache) recognized to occur in the oral and associated regions and incorporating a broad array of measures consistent ..
  34. Abdu F Azad; Fiscal Year: 2014
    ..RMSF is characterized by headache, fever, myalgia, nausea and vomiting early in the illness and if untreated it could progress to multi-organ ..
  35. ANDREW MARK STRASSMAN; Fiscal Year: 2014
    ..The headache field in particular for many years suffered from the severe limitation of having no behavioral assay...
  36. Formaldehyde and Other Pollutants from Ozone Reactions on Ventilation Systems
    Hugo Destaillats; Fiscal Year: 2010
    ..Asthma, allergies and frequent work-related non-specific symptoms (i.e., irritation, headache and fatigue) are strongly associated with exposure to airborne pollutants in non-industrial workplaces...
  37. John Douglas Mann; Fiscal Year: 2016
    ..It is therefore essential to investigate non-pharmacologic approaches to conventional headache treatments...
  38. Calvarial periosteal afferents in post-traumatic headache
    Dan Levy; Fiscal Year: 2012
    ..seemingly mild proportions of the trauma sustained, many injured individuals develop shortly after a debilitating headache, which can persist for months and even years...
  39. Coupling mechanisms of NOP receptors and calcium channels
    Victor Ruiz-Velasco; Fiscal Year: 2012
    ..and aid in the development of novel agents for the treatment of pain, such as those associated with chronic headache and complex region pain syndrome, and at the same time prevent opioid tolerance and addiction...
  40. Actuated Fine-Gauge Spinal Needle Insertion to Reduce Dura Damage and PDPH Risk
    MAUREEN L MULVIHILL; Fiscal Year: 2012
    ..SIS or 'Smooth Insertion Spinal') Needle Insertion Tool to Reduce Dural Damage and Post Dural Puncture Headache (PDPH)...
  41. Todd Schwedt; Fiscal Year: 2014
    ..The candidate is an Assistant Professor of Neurology and Anesthesiology and Director of the Washington University Headache Center in St. Louis, Missouri...
  42. ALICE ROGOT PRESSMAN; Fiscal Year: 2014
    ..The one-year prevalence of migraine headache in the United States is estimated to range from 8-15% overall affecting approximately three times more women than ..
  43. Role of CGRP in the association between migraine and obesity
    ANA RECOBER-MONTILLA; Fiscal Year: 2013
    ..me to build a career as a successful independent physician-scientist devoted to the study of migraine and other headache disorders. Drs. Russo and Hammond will be my mentors at The University of Iowa...
  44. Neural &Vascular Dysfunction As Mechanisms of Injury in Genetic Migraine Models
    Cenk Ayata; Fiscal Year: 2012
    ..questions about mechanisms of migraine aura that are relevant to understand the susceptibility for increasing headache frequency and progression (see RFA)...
  45. Civamide Nasal Spray for the Treatment of Postherpetic Neuralgia of the Trigemina
    Scott B Phillips; Fiscal Year: 2013
    ..mechanism of action has been observed when Civamide Nasal Spray is applied to the nasal mucosa in subjects with headache disorders mediated by the [TN], e.g...
  46. Vision In Preschoolers - Hyperopia in Children (VIP-HIP)
    Marjean T Kulp; Fiscal Year: 2013
    ..The requirement for accommodation in the uncorrected hyperope may result in eyestrain, headache, intermittent blur and difficulty attending at near, leading to subsequent reading and school performance ..
  47. Gene Therapy for Nerve Injury
    Luc Jasmin; Fiscal Year: 2010
    ..Our project is a pre-clinical study of the analgesic effects of correcting trigeminal nerve dysfunction by adding a gene that codes for GABA, a natural neurotransmitter to trigeminal nerve neurons. ..
  48. Rae Nishi; Fiscal Year: 2016
    ..Affective Disorder, Klein-Levin Syndrome, Sleep Disorders, Binging, Epilepsy, Multiple Sclerosis, Jet-Lag and Headache. The course on Methods in Computational Neuroscience presented in this proposal is an intensive program, taught ..
  49. TIMOTHY AIDAN RYAN; Fiscal Year: 2016
    ..Many known genetic mutations in diseases such as Parkinson's disease, migraine headache and schizophrenia are linked to proteins that control synapse function...
  50. Tonya M Palermo; Fiscal Year: 2014
    ..estimated 15% to 30% of otherwise healthy children and adolescents suffer from recurrent or chronic pain such as headache, abdominal pain, and musculoskeletal pain...
  51. Development and Validation of Measures of Pain Behaviors in Chronic Pain
    KARON FRANCES COOK; Fiscal Year: 2010
    ..Chronic pain complaints include headache, low back pain, cancer pain, arthritis pain, neurogenic pain (pain resulting from damage to the peripheral nerves ..
  52. Genetic targeting of CGRP actions in a murine model of migraine
    ERIC ALAN KAISER; Fiscal Year: 2011
    ..biological pathways in the brain, these studies could reveal new ways to manage and treat migraines and other headache disorders. NOTE: The critiques of individual reviewers are provided below in an essentially unedited form...
  53. Marek Swoboda; Fiscal Year: 2014
    ..Shunts frequently malfunction, usually by obstruction, but the symptoms of shunt failure are unspecific - headache, nausea...
  54. TeenMigraineConnection: Web-based self-management training for adolescents with m
    ELIZABETH ANNA DONOVAN; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Headache is a frequent health problem in children and adolescents (Winner &Rothner, 2001)...
  55. ROLE OF CENTRAL AND PERIPHERAL SEROTONIN IN MIGRAINE PATHOPHYSIOLOGY
    Yuqing Cao; Fiscal Year: 2012
    ..Nevertheless, the causal relationship between abnormal 5-HT level and the manifestation of migraine headache has not been firmly established...
  56. Christopher S Coffey; Fiscal Year: 2014
    ..Because amitriptyline (AMI) and topiramate (TPM) are commonly used by pediatric headache specialists, but currently lack the empirical data to be recommended as Class I evidence in the American Academy ..
  57. Scott W Powers; Fiscal Year: 2014
    ..Because amitriptyline (AMI) and topiramate (TPM) are commonly used by pediatric headache specialists, but currently lack the empirical data to be recommended as Class I evidence in the American Academy ..
  58. Hydrocephalus: Reducing Catheter Failure and Improving Diagnostic Capabilities
    Thomas Clement; Fiscal Year: 2011
    ..failure is often a neurosurgical emergency that can result in death;progressive failure involves vague symptoms (headache, nausea) that are difficult to diagnose, especially in children, and can lead to prolonged suffering before shunt ..
  59. New Strategies to Treat Overactive Bladder
    Changfeng Tai; Fiscal Year: 2013
    ..within 6-12 months due to its moderate efficacy and significant adverse effects such as dry mouth, constipation, headache, and blurred vision...
  60. Therapeutic Massage for Management of Pain &Disability in Tension-Type Headache
    ALBERT F MORASKA; Fiscal Year: 2011
    DESCRIPTION (provided by applicant): Chronic or episodic forms of tension-type headache (TTH) affect a high percentage of the population and not only impact personal life, but also pose a significant socio-economic burden in terms of ..
  61. William Maixner; Fiscal Year: 2014
    DESCRIPTION (provided by applicant): Complex persistent pain conditions (CPPCs) such as headache conditions, fibromyalgia, temporomandibular disorders, irritable bowel syndrome, and vulvar vestibulitis are high prevalent and shared or ..
  62. Cerebrovascular Afferent Mechanisms of Migraine
    ANDREA MARIE HARRIOTT; Fiscal Year: 2010
    ..The results from these experiments should help provide unique targets for the treatment of migraine pain and increase the understanding of cerebrovascular afferent mechanisms in initiating migraine pain. ..
  63. MODULATORY ROLE OF GABA AND 5HT RECEPTORS IN MIGRAINE
    F Cutrer; Fiscal Year: 1999
    Despite the fact that vascular head pain including migraine and cluster headache afflicts up to 15% of the population and inflicts significant suffering and economic loss, its pathophysiology and mechanism of treatment remain obscure...
  64. The Treatment of Methotrexate Resistant Rheumatoid Arthritis With Aminopterin
    Stuart Kahn; Fiscal Year: 2009
    ..are gastrointestinal and central nervous system side effects that include nausea, stomatitis, liver irritation, headache, fatigue, disorientation and poor memory...
  65. Synaptic Defects in the Ca Channel Mutant Mouse
    Kathleen Dunlap; Fiscal Year: 2004
    ..encoding class A (or P/Q-type) calcium channels are associated with multiple abnormalities, ranging from migraine headache to motor ataxias to absence epileptic seizures...
  66. ACTIVITY OF VISCERAL & NOCICEPTIVE TRIGEMINAL NEURONS
    Andrew Strassman; Fiscal Year: 1992
    ..Determine the location and morphology of brainstem trigeminovascular neurons. The location, somadendritic morphology, and initial axonal trajectory of neurons that peroxidase, and compared to neurons that receive only a cutaneous input. ..
  67. Race in Physician Decision to Prescribe Opioid Analgesia
    JOSHUA SARVER; Fiscal Year: 2002
    ..use of analgesics for 3 acute, painful conditions (back pain with sciatica, ankle fracture, and migraine headache); 2) whether providing information on patients? socioeconomic status, role impairment, and likelihood that ..
  68. Nitric Oxide and Chronic Rhinosinusitis
    Abraham Jacob; Fiscal Year: 2001
    ..are believed to result in mucosal disruption and hypersecretion, nasal obstruction, postnasal discharge, cough, headache, and facial pressure...
  69. INDIVIDUAL FACTORS IN NASAL IRRITANT SENSITIVITY
    Dennis Shusterman; Fiscal Year: 2002
    ..pollution, including eye, nose, and throat irritation (as well as reflex nasal congestion, rhinorrhea, and sinus headache) are either mediated (or triggered) by trigeminal chemoreception...
  70. A Twin Study of Chronic Fatigue Syndrome in Sweden
    Nancy Pedersen; Fiscal Year: 2003
    ..Registry for persistent fatigue, several overlapping conditions (fibromyalgia, irritable bowel syndrome, tension headache, allergy/eczema, generalized anxiety disorder, and major depression), and a detailed medical history...
  71. Novel therapy for female sexual dysfunction
    Garry Southan; Fiscal Year: 2001
    ..nitric oxide donors to the female genitalia, however, produces profound systemic side effects, including headache and hypotension...
  72. Genomics of Pediatric Headache Disorders
    Andrew Hershey; Fiscal Year: 2006
    ..proposal is designed to confirm these initial findings, and to determine whether acute migraine and chronic daily headache patients have similar or different blood genomic profiles, and whether there is a different blood genomic profile ..
  73. Dose-Response of Manipulation for Chronic Headache
    Mitchell Haas; Fiscal Year: 2006
    ..suggesting the efficacy of spinal manipulation, the signature therapy of chiropractic (DC) care, for chronic headache (HA)...
  74. Neurological sequelae in survivors of West Nile virus infection: a hamster model
    Cynthia Smeraski; Fiscal Year: 2009
    ..altered mental states, irritability, myalgia, acute flaccid paralysis, limb weakness, difficulty walking, and headache. In rodent models of flavivirus encephalitis, similar neurologic symptoms were observed in terms of abnormalities ..
  75. DEFINITION OF THE CHRONIC EPSTEIN-BARR VIRUS SYNDROME
    James Jones; Fiscal Year: 1990
    ..To this end, patients who have had varying combinations of pharyngitis, lymphadenopathy, headache, fatigue, myalgia, arthralgia, neuralgia, paresthesis, depression and dyslogia for over two years, and four ..
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    ERIK WOODS; Fiscal Year: 2006
    ..However, reinfusion of DMSO has long been associated with various adverse events, ranging from skin flushing, headache, fever, dyspnea, abdominal cramping, nausea, and diarrhea to more sever effects such as, hemolysis, ..