facial pain

Summary

Summary: Pain in the facial region including orofacial pain and craniofacial pain. Associated conditions include local inflammatory and neoplastic disorders and neuralgic syndromes involving the trigeminal, facial, and glossopharyngeal nerves. Conditions which feature recurrent or persistent facial pain as the primary manifestation of disease are referred to as FACIAL PAIN SYNDROMES.

Top Publications

  1. pmc Adaptation of a novel operant orofacial testing system to characterize both mechanical and thermal pain
    Todd A Nolan
    Center for Comprehensive Pain Research, University of Florida, Gainesville, FL, USA
    Behav Brain Res 217:477-80. 2011
  2. pmc Characterization of bilateral trigeminal constriction injury using an operant facial pain assay
    H L Rossi
    College of Dentistry Department of Orthodontics, University of Florida, Gainesville, FL, United States
    Neuroscience 224:294-306. 2012
  3. ncbi Use of a novel thermal operant behavioral assay for characterization of orofacial pain sensitivity
    John K Neubert
    Department of Orthodontics, College of Dentistry, University of Florida, 1600 SW Archer Road, P O Box 100444, Gainesville, FL 32610 0444, USA
    Pain 116:386-95. 2005
  4. ncbi Prevalence of temporomandibular dysfunction and its association with malocclusion in children and adolescents: an epidemiologic study related to specified stages of dental development
    Birgit Thilander
    Faculty of Odontology, Department of Orthodontics, Goteborg University, Sweden
    Angle Orthod 72:146-54. 2002
  5. ncbi Do illness perceptions predict pain-related disability and mood in chronic orofacial pain patients? A 6-month follow-up study
    Ursula Galli
    Clinic for Masticatory Disorders, Removable Prosthodontics and Special Care Dentistry, Center for Oral Medicine, Dental and Maxillo Facial Surgery, University of Zurich, Switzerland
    Eur J Pain 14:550-8. 2010
  6. pmc Characterization of cold sensitivity and thermal preference using an operant orofacial assay
    Heather L Rossi
    College of Dentistry Department of Orthodontics, University of Florida, Gainesville, FL 32610 0444, USA
    Mol Pain 2:37. 2006
  7. pmc Characterization of mouse orofacial pain and the effects of lesioning TRPV1-expressing neurons on operant behavior
    John K Neubert
    Department of Orthodontics, College of Dentistry, University of Florida, Gainesville, FL, USA
    Mol Pain 4:43. 2008
  8. ncbi Low-level laser therapy for treatment of temporomandibular joint pain: a double-blind and placebo-controlled trial
    Rüdiger Emshoff
    Department of Oral and Maxillofacial Surgery, Innsbruck Medical University, Innsbruck, Austria
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:452-6. 2008
  9. ncbi Trigeminal neuralgia: the diagnosis and management of this excruciating and poorly understood facial pain
    Joanna M Zakrzewska
    Oral Medicine Department, Eastman Dental Hospital, London, UK
    Postgrad Med J 87:410-6. 2011
  10. ncbi Headache and temporomandibular disorders: evidence for diagnostic and behavioural overlap
    A G Glaros
    Kansas City University of Medicine and Biosciences, Kansas City, MO 64106, USA
    Cephalalgia 27:542-9. 2007

Detail Information

Publications286 found, 100 shown here

  1. pmc Adaptation of a novel operant orofacial testing system to characterize both mechanical and thermal pain
    Todd A Nolan
    Center for Comprehensive Pain Research, University of Florida, Gainesville, FL, USA
    Behav Brain Res 217:477-80. 2011
    ..We demonstrate that the operant system is able to detect painful and analgesic responses to mechanical stimuli. These findings allow comparison of both mechanical and thermal stimuli using the same outcome measures...
  2. pmc Characterization of bilateral trigeminal constriction injury using an operant facial pain assay
    H L Rossi
    College of Dentistry Department of Orthodontics, University of Florida, Gainesville, FL, United States
    Neuroscience 224:294-306. 2012
    ..Understanding this relationship will allow us to better treat and prevent chronic neuropathic pain...
  3. ncbi Use of a novel thermal operant behavioral assay for characterization of orofacial pain sensitivity
    John K Neubert
    Department of Orthodontics, College of Dentistry, University of Florida, 1600 SW Archer Road, P O Box 100444, Gainesville, FL 32610 0444, USA
    Pain 116:386-95. 2005
    ..These data reflect an orofacial pain behavior profile that was based on an animal's responses in an operant escape paradigm. This technique allows evaluation of nociceptive processing and modulation throughout the neuraxis...
  4. ncbi Prevalence of temporomandibular dysfunction and its association with malocclusion in children and adolescents: an epidemiologic study related to specified stages of dental development
    Birgit Thilander
    Faculty of Odontology, Department of Orthodontics, Goteborg University, Sweden
    Angle Orthod 72:146-54. 2002
    ..Girls were in general more affected than boys. Significant associations were found between different signs, and TMD was associated with posterior crossbite, anterior open bite, Angle Class III malocclusion, and extreme maxillary overjet...
  5. ncbi Do illness perceptions predict pain-related disability and mood in chronic orofacial pain patients? A 6-month follow-up study
    Ursula Galli
    Clinic for Masticatory Disorders, Removable Prosthodontics and Special Care Dentistry, Center for Oral Medicine, Dental and Maxillo Facial Surgery, University of Zurich, Switzerland
    Eur J Pain 14:550-8. 2010
    ....
  6. pmc Characterization of cold sensitivity and thermal preference using an operant orofacial assay
    Heather L Rossi
    College of Dentistry Department of Orthodontics, University of Florida, Gainesville, FL 32610 0444, USA
    Mol Pain 2:37. 2006
    ..Male and female rats were trained to drink sweetened milk while pressing their shaved faces against a thermode. This presents a conflict paradigm between milk reward and thermal stimulation...
  7. pmc Characterization of mouse orofacial pain and the effects of lesioning TRPV1-expressing neurons on operant behavior
    John K Neubert
    Department of Orthodontics, College of Dentistry, University of Florida, Gainesville, FL, USA
    Mol Pain 4:43. 2008
    ..During the reward-conflict task, mice accessed a sweetened milk reward solution by voluntarily position their face against a neutral or heated thermode (37-55 degrees C)...
  8. ncbi Low-level laser therapy for treatment of temporomandibular joint pain: a double-blind and placebo-controlled trial
    Rüdiger Emshoff
    Department of Oral and Maxillofacial Surgery, Innsbruck Medical University, Innsbruck, Austria
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 105:452-6. 2008
    ..The objective of this study was to assess the effectiveness of low-level laser therapy (LLLT) in the management of temporomandibular joint (TMJ) pain in a random and double-blind research design...
  9. ncbi Trigeminal neuralgia: the diagnosis and management of this excruciating and poorly understood facial pain
    Joanna M Zakrzewska
    Oral Medicine Department, Eastman Dental Hospital, London, UK
    Postgrad Med J 87:410-6. 2011
    ..2-0.4% risk of mortality with a 2-4% chance of ipsilateral hearing loss. Surgical procedures result in markedly improved quality of life. Patient support groups provide information and support to those in pain and play a crucial role...
  10. ncbi Headache and temporomandibular disorders: evidence for diagnostic and behavioural overlap
    A G Glaros
    Kansas City University of Medicine and Biosciences, Kansas City, MO 64106, USA
    Cephalalgia 27:542-9. 2007
    ..These results are similar to those reported for TMD patients and they suggest that headache patients and TMD patients overlap considerably in diagnosis and oral parafunctional behaviours...
  11. ncbi Incidence of facial pain in the general population
    Joseph S H A Koopman
    Dept of Medical Informatics, Erasmus MC, Rotterdam, The Netherlands
    Pain 147:122-7. 2009
    b>Facial pain has a considerable impact on quality of life. Accurate incidence estimates in the general population are scant...
  12. ncbi The orofacial formalin test
    Patrick Raboisson
    INSERM E 0216, Neurolbiologie de La Douleur Trigéminale, Faculte de Chirurgie Dentaire, Clermont Ferrand, France
    Neurosci Biobehav Rev 28:219-26. 2004
    ..The orofacial formalin test can then be considered as a reliable way of producing and quantifying nociception in the trigeminal region of the rat...
  13. ncbi Orofacial deep and cutaneous tissue inflammation and trigeminal neuronal activation. Implications for persistent temporomandibular pain
    H Imbe
    Department of Oral and Craniofacial Biological Sciences, University of Maryland Dental School, Baltimore, MD, USA
    Cells Tissues Organs 169:238-47. 2001
    ..Since deep inputs may be more effective in inducing central neuronal excitation than cutaneous inputs, greater sensory disturbances may occur in pain conditions involving deep tissues than in those involving cutaneous tissues...
  14. ncbi Pathways between temporomandibular disorders, occlusal characteristics, facial pain, and oral health-related quality of life among patients with severe malocclusion
    Jaana Rusanen
    Department of Oral Development and Orthodontics, Institute of Dentistry, PO Box 5281, FIN 90014, Finland
    Eur J Orthod 34:512-7. 2012
    ..of this study was to examine the pathways between temporomandibular disorders (TMDs), occlusal characteristics, facial pain, and oral health-related quality of life in patients with severe malocclusion...
  15. ncbi Persistent facial pain increases superoxide anion production in the spinal trigeminal nucleus
    Emanuela Viggiano
    Department of Experimental Medicine, Second University of Naples, Naples, Italy
    Mol Cell Biochem 339:149-54. 2010
    ..The purpose of the present study was to evaluate the possible role of O(2) (-) in the transmission of oro-facial pain. Formaldehyde 1% was injected subcutaneously into one vibrissal pad of adult male Sprague-Dawley rats as a ..
  16. ncbi Dentists' and specialists' knowledge of chronic orofacial pain: results from a continuing professional development survey
    Vishal R Aggarwal
    National Institute for Health Research NIHR, Oral Health Unit, School of Dentistry, University of Manchester, Manchester, UK
    Prim Dent Care 18:41-4. 2011
    ..To explore the knowledge of chronic orofacial pain within general dental practitioners (GDPs) and dental specialists...
  17. pmc The dolognawmeter: a novel instrument and assay to quantify nociception in rodent models of orofacial pain
    John C Dolan
    Department of Orofacial Sciences, University of California, San Francisco, USA
    J Neurosci Methods 187:207-15. 2010
    ..This assay will be useful in the study of nociceptive mediators involved in the development and progression of orofacial pain conditions and it will also provide a unique tool for development and assessment of new therapeutic approaches...
  18. ncbi Topical clonazepam in stomatodynia: a randomised placebo-controlled study
    Christelle Gremeau-Richard
    INSERM E 0216, Neurobiologie de la douleur trigeminale, Faculte de Chirurgie Dentaire, CHU Clermont Ferrand, Clermont Ferrand 63000, France
    Pain 108:51-7. 2004
    ..It is hypothesised that clonazepam acts locally to disrupt the mechanism(s) underlying stomatodynia...
  19. ncbi The prevalence of clinical diagnostic groups in patients with temporomandibular disorders
    Luciana Pimenta e Silva Machado
    Federal University of Goias, School of Dentistry, Goiania, Brazil
    Cranio 27:194-9. 2009
    ....
  20. pmc Effects of hot and cold stimulus combinations on the thermal preference of rats
    Heather L Rossi
    College of Dentistry Department of Orthodontics, University of Florida, Gainesville, FL, United States
    Behav Brain Res 203:240-6. 2009
    ..The findings in this study will allow us to evaluate experimental pain states and analgesic treatments in a manner more relatable to the experience of the patient...
  21. ncbi Temporomandibular disorders and facial pain: a psychophysiological perspective
    Alan G Glaros
    Kansas City University of Medicine and Biosciences, Kansas City, MO 64106, USA
    Appl Psychophysiol Biofeedback 33:161-71. 2008
    ..article presents a psychophysiological perspective on temporomandibular muscle and joint disorders (TMJD) and facial pain. After a brief introduction to TMJD, the article presents data, largely derived from work carried out in my ..
  22. pmc Patient-centered outcome criteria for successful treatment of facial pain and fibromyalgia
    Lauren A Stutts
    Department of Clinical and Health Psychology, University of Florida, Gainesville, Florida, USA
    J Orofac Pain 23:47-53. 2009
    To define treatment success from the facial pain and fibromyalgia pain patient perspective across four domains (pain, fatigue, emotional distress, interference with daily activities) through the use of the Patient-Centered Outcomes (PCO) ..
  23. ncbi Nonspecific chronic orofacial pain: studying patient experiences and perspectives with a qualitative approach
    Eva Wolf
    Department of Endodontics Faculty of Odontology Malmö University Malmö, Sweden
    J Orofac Pain 22:349-58. 2008
    ..To analyze the nonspecific chronic orofacial pain patient's experience of the pain condition and to gain knowledge on the complexity of the problem...
  24. ncbi Patients' experiences of consultations for nonspecific chronic orofacial pain: A phenomenological study
    Eva Wolf
    Department of Endodontics, Faculty of Odontology, Malmo University, Malmo, Sweden
    J Orofac Pain 20:226-33. 2006
    ..To use a qualitative research study to analyze the experiences of patients with nonspecific chronic orofacial pain with respect to consultations for their pain condition...
  25. ncbi Prevalence of myofascial temporomandibular disorder in US community women
    M N Janal
    Department of Psychiatry, NJ Medical School, UMDNJ, NJ, USA
    J Oral Rehabil 35:801-9. 2008
    ..M-TMD) defined by Research Diagnostic Criteria (RDC), and relates that prevalence to the surveyed report of facial pain. From among 20 000 women selected at random in the NY metropolitan area who completed a telephone survey of ..
  26. pmc Trigeminal neuralgia and its management
    Luke Bennetto
    Institute of Clinical Neurosciences, University of Bristol, Frenchay Hospital, Bristol BS16 1LE
    BMJ 334:201-5. 2007
  27. ncbi The role of parafunctions, emotions and stress in predicting facial pain
    Alan G Glaros
    Kansas City University of Medicine and Biosciences, MO 64106, USA
    J Am Dent Assoc 136:451-8. 2005
    ..The authors conducted a study to examine the degree to which parafunctions and emotional states predicted jaw pain in subjects with temporomandibular disorder (TMD) and control subjects...
  28. ncbi Persistent dentoalveolar pain: the patient's experience
    Justin Durham
    Newcastle University, Newcastle upon Tyne, UK
    J Orofac Pain 27:6-13. 2013
    ..To build an understanding of the patient's experience and from this identify recurring themes that could form part of an item pool for further testing of persistent dentoalveolar pain disorder (PDAP)...
  29. ncbi The orofacial formalin test in mice revisited--effects of formalin concentration, age, morphine and analysis method
    Manuel Bornhof
    Anästhesiologische Klinik, Universitatsklinikum Erlangen, Erlangen, Germany
    J Pain 12:633-9. 2011
    ..Morphine dose dependently suppressed the nociceptive behavior and the number of score 3 ratings of the nociceptive behavior. Age differences in behavior could not be detected by either analytic method...
  30. pmc Clinical findings and pain symptoms as potential risk factors for chronic TMD: descriptive data and empirically identified domains from the OPPERA case-control study
    Richard Ohrbach
    Department of Oral Diagnostic Sciences, University at Buffalo, State University of New York, Buffalo, New York 14214, USA
    J Pain 12:T27-45. 2011
    ..Future analyses will examine their contribution to TMD onset...
  31. pmc Attitudes of a group of Brazilian orthodontists towards the diagnosis and management of primary headache (migraine): an electronic-based survey
    Reynaldo Leite Martins Júnior
    Dental School, Univag Centro Universitário Várzea Grande, Cuiaba, MT, Brazil
    J Appl Oral Sci 19:674-8. 2011
    ..The aim of this study was to investigate the knowledge and attitudes of orthodontists in the diagnosis and management of migraine without aura...
  32. pmc The role of trigeminal interpolaris-caudalis transition zone in persistent orofacial pain
    Ke Ren
    Department of Neural and Pain Sciences, Dental School and Program in Neuroscience, University of Maryland, Baltimore, MD 21201 1586, USA
    Int Rev Neurobiol 97:207-25. 2011
    ..The Vi/Vc transition zone accesses rostral brain regions that are important for descending pain modulation, and somatovisceral and somatoautonomic processing and plays a unique role in coordinating trigeminal nocifensive responses...
  33. ncbi Effectiveness of low-level laser therapy in temporomandibular disorders: a systematic review and meta-analysis
    Ambra Petrucci
    Gnathology Department, School of Dentistry, University of L Aquila, L Aquila, Italy
    J Orofac Pain 25:298-307. 2011
    ..To assess the scientific evidence on the efficacy of low-level laser therapy (LLLT) in the treatment of temporomandibular disorders (TMD)...
  34. pmc Assessment of chronic trigeminal neuropathic pain by the orofacial operant test in rats
    Myeounghoon Cha
    Department of Anesthesiology and the Graduate Program in Neuroscience, The University of Cincinnati College of Medicine, PO Box 670531, 231 Albert Sabin Way, Cincinnati, OH 45267 0531, USA
    Behav Brain Res 234:82-90. 2012
    ..The neuropathic pain in ION-CCI rats was partially alleviated by morphine. Thus, orofacial operant test provides a desirable behavioral assessment method for preclinical studies of chronic trigeminal neuropathic pain...
  35. ncbi Diagnostic criteria for headache attributed to temporomandibular disorders
    Eric Schiffman
    Department of Diagnostic and Biological Sciences, University of Minnesota School of Dentistry, MN 55108, USA
    Cephalalgia 32:683-92. 2012
    ..We assessed and compared the diagnostic accuracy of two sets of diagnostic criteria for headache secondary to temporomandibular disorders (TMD)...
  36. ncbi Retrospective examination of the healthcare 'journey' of chronic orofacial pain patients referred to oral and maxillofacial surgery
    E V Beecroft
    School of Dental Sciences, Newcastle University, Framlington Place, Newcastle upon Tyne, NE2 4BW, UK
    Br Dent J 214:E12. 2013
    ..To gain a deeper understanding of the clinical journey taken by orofacial pain patients from initial presentation in primary care to treatment by oral and maxillofacial surgery...
  37. ncbi Orofacial pain of cardiac origin: a case report
    Braz C Durso
    Stomatology Post Graduate Program, Federal University of Rio de Janeiro, Brazil
    Cranio 21:152-3. 2003
    ..In rare instances the pain may present as dental pain. In this case report, the patient presented with complaints of intense bilateral pain in the jaws which was diagnosed as pain of cardiac origin...
  38. ncbi Effectiveness of low-level laser therapy in temporomandibular joint disorders: a placebo-controlled study
    H Fikackova
    Institute of Biophysics and Informatics, 1st Medical Faculty, Charles University, Prague, Czech Republic
    Photomed Laser Surg 25:297-303. 2007
    ..Low-level laser therapy (LLLT) treatment for pain caused by temporomandibular joint disorders (TMD) was investigated in a controlled study comparing applied energy density, subgroups of TMD, and duration of disorders...
  39. ncbi Facial pain of cardiac origin: a case report
    Ana Carolina de Oliveira Franco
    Hospital das Clinicas, Instituto do Coracao, Faculdade de Medicina, Universidade de Sao Paulo, Rua Capote Valente 668, Pinheiros, CEP 05409 002 São Paulo, Brazil
    Sao Paulo Med J 124:163-4. 2006
    ..Cardiac pain may radiate to the face and lead patients to seek dental care. Dentists may contribute towards the diagnosing of ischemic heart disease and thus refer patients for cardiological evaluation...
  40. ncbi Craniofacial pain as the sole symptom of cardiac ischemia: a prospective multicenter study
    Marcelo Kreiner
    Oral and Maxillofacial Radiology, Department of Odontology, Umea University, Umea, Sweden
    J Am Dent Assoc 138:74-9. 2007
    ..Failure to recognize its cardiac source can put the patient's life at risk. The authors conducted a study to reveal the prevalence of, the distribution of and sex differences regarding craniofacial pain of cardiac origin...
  41. ncbi Kinin B(1) and B(2) receptors contribute to orofacial heat hyperalgesia induced by infraorbital nerve constriction injury in mice and rats
    Ana Paula Luiz
    Department of Pharmacology, Universidade Federal de Santa Catarina, Florianopolis, SC, Brazil
    Neuropeptides 44:87-92. 2010
    ..Perhaps kinin B(1) and B(2) receptor antagonists might constitute effective preventive and curative treatments for orofacial thermal hyperalgesia induced by nerve injury...
  42. ncbi Bilateral facial pain from cardiac origin. A case report
    A C de Oliveira Franco
    Hospital das Clínicas and Heart Institute InCor, University of Sao Paulo Medical School, Rua Alves Guimarães 408, Apto 184, Sao Paulo, SP 05410 000, Brazil
    Br Dent J 198:679-80. 2005
    A case of a 65-year-old female patient is reported. Her chief complaint was facial pain, so she sought care from her general dental practitioner for evaluation of a suspected temporomandibular disorder, after repeated visits to the ..
  43. ncbi Temporomandibular joint pain: relationship to internal derangement type, osteoarthrosis, and synovial fluid mediator level of tumor necrosis factor-alpha
    R Emshoff
    University of Innsbruck, Department of Oral and Maxillofacial Surgery, Austria
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 90:442-9. 2000
    ....
  44. ncbi Facial pain: an update
    Joanna M Zakrzewska
    Division of Diagnostic, Surgical and Medical Sciences, Eastman Dental Hospital, UCLH NHS Foundation Trust, London, UK
    Curr Opin Support Palliat Care 3:125-30. 2009
    Review current literature in the field of chronic nondental facial pain as recent clinical research findings need to be put into practise.
  45. pmc Classifying orofacial pains: a new proposal of taxonomy based on ontology
    D R Nixdorf
    Division of TMD and Orofacial Pain and Department of Neurology, University of Minnesota, Minneapolis, MN, USA
    J Oral Rehabil 39:161-9. 2012
    ..This is an initial first step towards developing a coherent taxonomy for orofacial pain disorders, which is needed to improve clinical research and care...
  46. pmc Distinctive response of CNS glial cells in oro-facial pain associated with injury, infection and inflammation
    Seunghwan Lee
    The Alan Edwards Centre for Research on Pain, McGill University, 740, Dr, Penfield Ave, Montreal, Quebec, H3A 2B2, Canada
    Mol Pain 6:79. 2010
    Oro-facial pain following injury and infection is frequently observed in dental clinics...
  47. ncbi Measurements of jaw movements and TMJ pain intensity in patients treated with GaAlAs laser
    Marcelo Oliveira Mazzetto
    Departamento de Odontologia Restauradora, Ribeirao Preto Dental School, University of Sao Paulo, Ribeirao Preto, SP, Brazil
    Braz Dent J 21:356-60. 2010
    ..The same results were not observed in the placebo group...
  48. ncbi Cervicomedullary junction spinal cord stimulation for head and facial pain
    Nestor D Tomycz
    Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    Headache 51:418-25. 2011
    To review our experience with cervicomedullary junction spinal cord stimulation (SCS), to alleviate head and facial pain.
  49. ncbi Nonfunctional tooth contact in healthy controls and patients with myogenous facial pain
    Cheng yi Chen
    Clinic for Masticatory Disorders, Removable Prosthodontics and Special Care Dentistry, Centre for Oral Medicine, Dental and Maxillo Facial Surgery, University of Zurich, Switzerland
    J Orofac Pain 21:185-93. 2007
    ....
  50. ncbi Angina masquerading as sinusitis
    A Christoforidou
    Department of Otolaryngology, Derriford Hospital, Plymouth, UK
    J Laryngol Otol 120:961-2. 2006
    b>Facial pain of cardiac origin is rare. There are several references in the world literature to angina referred to the teeth and the mandible...
  51. ncbi Classification, causation and treatment of masticatory myogenous pain and dysfunction
    Glenn T Clark
    Department of Diagnostic Sciences, University of Southern California, School of Dentistry, 925 West 34th Street, Los Angeles, CA 90089 0641, USA
    Oral Maxillofac Surg Clin North Am 20:145-57, v. 2008
    ..The probable mechanisms are discussed and treatment options, including self-directed treatment, physical medicine modalities, and several types of pharmacologic agents, are presented...
  52. ncbi Quality difference in craniofacial pain of cardiac vs. dental origin
    M Kreiner
    Department of Oral and Maxillofacial Radiology, Umea University, SE 901 87 Umea, Sweden
    J Dent Res 89:965-9. 2010
    ..To initiate prompt and appropriate treatment, dental and medical clinicians as well as the public should be alert to those clinical characteristics of craniofacial pain of cardiac origin...
  53. ncbi Temporomandibular disorders and headache
    Steven B Graff-Radford
    Pain Center, Cedars Sinai Medical Center, 444 South San Vicente, 1101 Los Angeles, CA 90048, USA
    Dent Clin North Am 51:129-44, vi-vii. 2007
    ..This article discusses the relationship between the TMJ, muscles, or other orofacial structures and headache...
  54. pmc The Research Diagnostic Criteria for Temporomandibular Disorders. V: methods used to establish and validate revised Axis I diagnostic algorithms
    Eric L Schiffman
    Department of Diagnostic and Biological Sciences, University of Minnesota, Minneapolis, MN 55455, USA
    J Orofac Pain 24:63-78. 2010
    ..To derive reliable and valid revised Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) Axis I diagnostic algorithms for clinical TMD diagnoses...
  55. ncbi Prevalence of temporomandibular pain and subsequent dental treatment in Swedish adolescents
    Ing Marie Nilsson
    Public Dental Service, Skarptorp, Norrkoping, Sweden
    J Orofac Pain 19:144-50. 2005
    ....
  56. ncbi Functional and psychosocial impact related to specific temporomandibular disorder diagnoses
    Daniel R Reissmann
    Department of Prosthodontics and Materials Science, University of Leipzig, Nürnberger Str 57, 04103 Leipzig, Germany
    J Dent 35:643-50. 2007
    ....
  57. ncbi Mechanisms and predictors of chronic facial pain in lateral medullary infarction
    S Fitzek
    Department of Neurology, University of Jena, Germany
    Ann Neurol 49:493-500. 2001
    ..in the ipsilateral face (6 patients) and/or the contralateral limbs and trunk (5 patients, 3 of whom also had facial pain)...
  58. ncbi Signs and symptoms of temporomandibular disorders in adolescents
    Leonardo Rigoldi Bonjardim
    Department of Oral Physiology, School of Dentistry of Piracicaba, State University of Campinas
    Braz Oral Res 19:93-8. 2005
    ..05), except for the tenderness of the lateral pterygoid muscles, which presented more prevalence in girls. In conclusion, clinical signs and symptoms of TMD can occur in adolescents; however, gender influence was not perceived...
  59. ncbi The impact of orofacial pain on the quality of life of patients with temporomandibular disorder
    Vinícius de Magalhães Barros
    Dental School of Pontifical Catholic University, Minas Gerais, Brazil
    J Orofac Pain 23:28-37. 2009
    ..To evaluate the relationships between gender, diagnosis, and severity of temporomandibular disorders (TMD) with self-reports of the impact of TMD on the quality of life...
  60. ncbi Role of psychosocial factors in the etiology of bruxism
    Daniele Manfredini
    TMD Clinic, University of Padova, Padova, Italy
    J Orofac Pain 23:153-66. 2009
    ..To summarize literature data about the role of psychosocial factors in the etiology of bruxism...
  61. pmc Glutamate and capsaicin effects on trigeminal nociception I: Activation and peripheral sensitization of deep craniofacial nociceptive afferents
    David K Lam
    Faculty of Dentistry, University of Toronto 124 Edward Street, Toronto, Ontario, Canada M5G 1G6
    Brain Res 1251:130-9. 2009
    ..The data further suggest that peripheral glutamate and capsaicin receptor mechanisms may interact to modulate the activation and peripheral sensitization in some deep craniofacial nociceptive afferents...
  62. ncbi Symptoms of temporomandibular disorders in the population: an epidemiological study
    Daniela Aparecida de Godoi Gonçalves
    Department of Dental Materials and Prosthodontics, Araraquara Dental School, Sao Paulo State University, Araraquara SP, Brazil
    J Orofac Pain 24:270-8. 2010
    ..To estimate the prevalence of symptoms of temporomandibular disorders (TMD) as a function of age and gender, in a representative urban sample from the Brazilian population...
  63. ncbi A longitudinal epidemiologic study of signs and symptoms of temporomandibular disorders from 15 to 35 years of age
    T Magnusson
    Department of Stomatognathic Physiology, The Institute for Postgraduate Dental Education, Jonkoping, Sweden
    J Orofac Pain 14:310-9. 2000
    ..To study the development over 20 years of signs and symptoms of temporomandibular disorders (TMD) in an epidemiologic sample and to analyze possible correlations between these signs and symptoms and some other variables...
  64. ncbi Trigeminal transition zone/rostral ventromedial medulla connections and facilitation of orofacial hyperalgesia after masseter inflammation in rats
    Shinichi Sugiyo
    Department of Biomedical Sciences, Dental School, and Program in Neuroscience, University of Maryland, Baltimore, Maryland 21201 1586, USA
    J Comp Neurol 493:510-23. 2005
    ..The Vi/Vc-RVM pathway is activated after orofacial deep tissue injury and plays a critical role in facilitating orofacial hyperalgesia...
  65. ncbi Intracisternal administration of mitogen-activated protein kinase inhibitors reduced mechanical allodynia following chronic constriction injury of infraorbital nerve in rats
    Eun J Lim
    Department of Oral Physiology and BrainKorea 21, School of Dentistry, Kyungpook National University, Daegu 700 412, South Korea
    Prog Neuropsychopharmacol Biol Psychiatry 31:1322-9. 2007
    ..Our findings suggest that MAPKs inhibitors have a potential role in treatment for orofacial neuropathic pain...
  66. ncbi The prevalence of temporomandibular joint dysfunction in the mixed dentition
    Virginie Tuerlings
    Department of Orthodontics, University Hospital, Liege, Belgium
    Eur J Orthod 26:311-20. 2004
    ..Assessment of the maximal amplitudes of mandibular movements did not reveal any limitations. These results indicate that few relationships exist between individual parameters and TMD signs...
  67. pmc Mechanisms involved in extraterritorial facial pain following cervical spinal nerve injury in rats
    Azusa Kobayashi
    Department of Oral Diagnosis, Nihon University School of Dentistry, 1 8 13 Kandasurugadai, Chiyoda ku, Tokyo, 101 8310, Japan
    Mol Pain 7:12. 2011
    ....
  68. ncbi Towards a new taxonomy of idiopathic orofacial pain
    Alain Woda
    EA 3847, Faculte de Chirurgie Dentaire, CHU Clermont Ferrand 63000, France
    Pain 116:396-406. 2005
    ..the taxonomy of the different forms of idiopathic orofacial pain (stomatodynia, atypical odontalgia, atypical facial pain, facial arthromyalgia), which are sometimes considered as separate entities and sometimes grouped together...
  69. ncbi Tremor induced by thalamic deep brain stimulation in patients with complex regional facial pain
    Constantine Constantoyannis
    Surgical Centre for Movement Disorders, University of British Columbia, Vancouver, British Columbia, Canada
    Mov Disord 19:933-6. 2004
    ..after chronic stimulation of the contralateral thalamus (VPM nucleus) during treatment of a complex regional facial pain syndrome...
  70. ncbi Pharmacologic interventions in the treatment of temporomandibular disorders, atypical facial pain, and burning mouth syndrome. A qualitative systematic review
    Thomas List
    Orofacial Pain Unit, Department of Stomatognathic Physiology, Malmo University, SE 214 21 Malmö, Sweden
    J Orofac Pain 17:301-10. 2003
    ..pain-relieving effect and safety of pharmacologic interventions in the treatment of chronic temporomandibular disorders (TMD), including rheumatoid arthritis (RA), as well as atypical facial pain (AFP), and burning mouth syndrome (BMS).
  71. ncbi Prevalence of facial pain in migraine: a population-based study
    M S Yoon
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cephalalgia 30:92-6. 2010
    ..head pain in migraine can extend involving the maxillary or mandibular region of the face, sometimes isolated facial pain is the only and atypical presentation of migraine...
  72. ncbi The International Classification of Headache Disorders: accurate diagnosis of orofacial pain?
    R Benoliel
    Department of Oral Medicine, Faculty of Dentistry, Hebrew University Hadassah, POB 12272, Jerusalem, Israel
    Cephalalgia 28:752-62. 2008
    ..Employing IHS criteria, 184 patients were successfully diagnosed (56%), including 34 with persistent idiopathic facial pain. In the remaining 144 we applied AAOP/RDCTMD criteria and diagnosed 120 as masticatory myofascial pain (MMP) ..
  73. ncbi Development of orofacial pain programs in dental schools
    James R Fricton
    University of Minnesota School of Dentistry, 515 Delaware Street SE, 15 209 Moos Tower, Minneapolis, MN 55455, USA
    J Orofac Pain 16:191-7. 2002
    ..These features may be of assistance to those considering the development of such programs in the United States and elsewhere in the world...
  74. pmc Serotonin type 1D receptors (5HTR) are differentially distributed in nerve fibres innervating craniofacial tissues
    A M Harriott
    Department of Biomedical Sciences and Medical Sciences Training Program, University of Maryland, Baltimore, MD, USA
    Cephalalgia 28:933-44. 2008
    ..An additional site of action at sympathetic efferents is also suggested...
  75. ncbi Disturbed jaw behavior in whiplash-associated disorders during rhythmic jaw movements
    B Häggman-Henrikson
    Department of Odontology, Clinical Oral Physiology, Umea University, S 901 87 Umea, Sweden
    J Dent Res 81:747-51. 2002
    ..In conclusion, these results show that neck trauma can derange integrated jaw and neck behavior, and underline the functional coupling between the jaw and head-neck motor systems...
  76. ncbi Facial pain and the second edition of the International Classification of Headache Disorders
    Karin Zebenholzer
    Department of Neurology, Medical University of Vienna, Austria
    Headache 46:259-63. 2006
    Recurrent or chronic facial pain may be a diagnostic challenge...
  77. pmc Risk factors for onset of chronic oro-facial pain--results of the North Cheshire oro-facial pain prospective population study
    Vishal R Aggarwal
    Oral Health Unit, School of Dentistry, Manchester Biomedical Research Centre, University of Manchester, Manchester M15 6FH, UK
    Pain 149:354-9. 2010
    ..to the cross-sectional nature of previous studies, whether mechanical factors predict the onset of Chronic oro-facial pain remains unclear...
  78. ncbi Effect of conventional TENS on pain and electromyographic activity of masticatory muscles in TMD patients
    Delaine Rodrigues
    Methodist University of Piracicaba
    Braz Oral Res 18:290-5. 2004
    ..It is possible to conclude that a single TENS application is effective in pain reduction. However, it does not act homogeneously on the features of the electric activity of the muscles evaluated...
  79. ncbi A review of complementary and alternative medicine use for treating chronic facial pain
    Cynthia D Myers
    Pediatric Pain Program, University of California Los Angeles School of Medicine, 90024, USA
    J Am Dent Assoc 133:1189-96; quiz 1259-60. 2002
    The authors compiled information on the prevalence of complementary and alternative medicine, or CAM, use, as well as on reports of randomized clinical trials of CAM modalities used to treat chronic facial pain.
  80. ncbi Temporomandibular disorders and oral health-related quality of life. A systematic review
    Lars Dahlström
    Research Center, Public Dental Service, Clinic of Odontology, Goteborg, Sweden
    Acta Odontol Scand 68:80-5. 2010
    ..It has also gained increased attention in temporomandibular disorders (TMDs) in recent years. The purpose of this study was to systematically review the literature on OHRQoL and TMDs...
  81. ncbi Peripheral administration of NR2 antagonists attenuates orofacial formalin-induced nociceptive behavior in rats
    Min K Park
    Department of Oral Physiology, School of Dentistry, Kyungpook National University, Daegu, Republic of Korea
    Prog Neuropsychopharmacol Biol Psychiatry 35:982-6. 2011
    ..These results indicate that a targeted blockade of peripheral NR2 receptors is a potentially important new method of treating inflammatory pain in the orofacial area...
  82. ncbi Clinical evaluation of tinnitus in patients with sleep bruxism: prevalence and characteristics
    C M Camparis
    Araraquara School of Dentistry, Sao Paulo State University UNESP, Sao Paulo, Brazil
    J Oral Rehabil 32:808-14. 2005
    ..difference between the two groups, with higher prevalence for the group A, in relation to: presence of chronic facial pain (P = 0.0007); number of areas painful to palpation in the masticatory and cervical muscles (P = 0...
  83. ncbi Prevalence of trigeminal neuralgia and persistent idiopathic facial pain: a population-based study
    Daniel Mueller
    University of Duisburg Essen, Germany
    Cephalalgia 31:1542-8. 2011
    To estimate the lifetime prevalence of trigeminal neuralgia (TN) and persistent idiopathic facial pain (PIFP) in a population-based sample in Germany.
  84. ncbi Motor cortex stimulation: functional magnetic resonance imaging-localized treatment for three sources of intractable facial pain
    Darian R Esfahani
    Stritch School of Medicine, Loyola University Medical Center, Maywood, Illinois, USA
    J Neurosurg 114:189-95. 2011
    Neuropathic facial pain can be a debilitating condition characterized by stabbing, burning, dysesthetic sensation...
  85. ncbi Management of chronic orofacial pain: a survey of general dentists in german university hospitals
    Stefan Wirz
    CURA Hospitals, Department for Anesthesiology, Interdisciplinary Intensive Care, Pain Therapy, Palliative Medicine, CURA Hospitals, Bad Honnef, Germany
    Pain Med 11:416-24. 2010
    ..This survey assessed procedures performed by general dentists in German university hospitals treating patients with chronic orofacial pain (COP)...
  86. ncbi Low level lasers in dentistry
    Gerry Ross
    Laser Light Canada
    Gen Dent 56:629-34. 2008
    ..This article investigates the clinical effects of LLLT and explains how it can be applied in the dental field...
  87. ncbi Anatomically and physiologically based guidelines for use of the sphenopalatine ganglion block versus the stellate ganglion block to reduce atypical facial pain
    R N Klein
    Facial Pain Center, University of the Pacific School of Dentistry, San Francisco, California 94115, USA
    Cranio 19:48-55. 2001
    ..needed for the use of a sphenopalatine ganglion block versus a stellate ganglion block to reduce atypical facial pain. We have reviewed the basic anatomy of both ganglia and the physiological responses usually associated with ..
  88. ncbi Application of a pro-inflammatory agent to the orbital portion of the rat infraorbital nerve induces changes indicative of ongoing trigeminal pain
    Rafael Benoliel
    The Department of Oral Diagnosis, Hadassah School of Dental Medicine, The Hebrew University, Jerusalem, Israel
    Pain 99:567-78. 2002
    ..This model of inflammation-induced neuropathic pain is highly applicable to the study of neuroinflammatory orofacial pain...
  89. ncbi Temporomandibular disorders: referred cranio-cervico-facial clinic
    Luis Miguel Ramirez
    Departamento de Ciencias Basicas, Universidad Industrial de Santander, Bucaramanga, Colombia
    Med Oral Patol Oral Cir Bucal 10:E18-26. 2005
    ..This offers better tools in the conservative therapy phase of this craniofacial referred symptomatology...
  90. ncbi Classification of chronic orofacial pain: applicability of chronic headache criteria
    Rafael Benoliel
    Department of Oral Medicine, Faculty of Dentistry, Hebrew University Hadassah, Jerusalem, Israel
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 110:729-37. 2010
    ..The aim of this study was to test the temporal definitions of chronic daily headache (CDH) in an orofacial pain population and examine the features of the so-defined chronic orofacial pain (COFP)...
  91. ncbi Botulinum toxin for radiation-induced facial pain and trismus
    Dana M Hartl
    Department of Otolaryngology Head and Neck Surgery, Institut Gustave Roussy, Villejuif, France
    Otolaryngol Head Neck Surg 138:459-463. 2008
    ..To report the efficacy of botulinum toxin A for radiation-induced pain, trismus, and masticator spasm in head and neck cancer...
  92. ncbi Neurologic diagnosis and treatment in patients with computed tomography and nasal endoscopy negative facial pain
    Eric P Paulson
    Department of Otolaryngology Head and Neck Surgery, University of Iowa, Iowa City, Iowa 52242 1093, USA
    Laryngoscope 114:1992-6. 2004
    To determine the helpfulness of specialist neurology referral for patients with facial pain, a normal sinus computed tomography (CT) scan, and normal nasal endoscopy findings.
  93. pmc Reliability and validity of Axis I of the Research Diagnostic Criteria for Temporomandibular Disorders (RDC/TMD) with proposed revisions
    J O Look
    Department of Diagnostic and Biological Sciences, School of Dentistry, University of Minnesota, Minneapolis, MN, USA
    J Oral Rehabil 37:744-59. 2010
    ....
  94. ncbi Peripheral painful traumatic trigeminal neuropathy: clinical features in 91 cases and proposal of novel diagnostic criteria
    Rafael Benoliel
    Department of Oral Medicine, Hebrew University, Hadassah, Jerusalem, Israel
    J Orofac Pain 26:49-58. 2012
    ..To field-test carefully designed criteria for pain following trigeminal nerve trauma...
  95. ncbi Jaw muscle soreness after tooth-clenching depends on force level
    M Farella
    Section of Clinical Oral Physiology, School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Denmark
    J Dent Res 89:717-21. 2010
    ..5% task. Temporalis pressure threshold decreased one day after the 7.5 % task (-14.6%; p = 0.003). It was concluded that prolonged low-level tooth-clenching in healthy young women induces a delayed soreness in the jaw elevator muscles...
  96. ncbi Migraine with isolated facial pain: a diagnostic challenge
    M Obermann
    Department of Neurology, University of Duisburg Essen, Essen, Germany
    Cephalalgia 27:1278-82. 2007
    ....
  97. ncbi Vagus nerve pain referred to the craniofacial region. A case report and literature review with implications for referred cardiac pain
    D E Myers
    Department of Oral Diagnosis, Dental Associates, Ltd Of Wisconsin, 11711 W Burleigh St, Wauwatosa, WI 53222, USA
    Br Dent J 204:187-9. 2008
    ..This leads to the hypothesis that the vagus nerve plays a role in mediating this pain. A review of the clinical and physiologic literature supports this hypothesis...
  98. ncbi Extraction of RDC/TMD subscales from the symptom check list-90: does context alter respondent behavior?
    Richard Ohrbach
    Professor Department of Oral Diagnostic Sciences, University at Buffalo Buffalo, New York, USA
    J Orofac Pain 22:331-9. 2008
    ....
  99. ncbi Stress-related adaptive versus maladaptive coping and temporomandibular disorder pain
    Daniel R Reissmann
    Department of Prosthetic Dentistry, University Medical Center, Hamburg Eppendorf, Hamburg, Germany
    J Orofac Pain 26:181-90. 2012
    ..To test whether patients with temporomandibular disorder (TMD) pain differ from subjects from the general population with regard to their stress-related coping styles...
  100. ncbi Headache disability in orofacial pain patients
    William E Dando
    Orofacial Pain Center, Naval Postgraduate Dental School, National Naval Medical Center, Bethesda, MD 20889, USA
    Headache 46:322-6. 2006
    ..To retrospectively examine the reported history of and the disability caused by headaches in patients presenting for evaluation and treatment of orofacial pain...
  101. ncbi Headache impact in patients with orofacial pain
    Somsak Mitrirattanakul
    Occlusion Unit, Faculty of Dentistry, Mahidol University, Bangkok, 6 Yothi Street, Ratchatevi, Bangkok, 10400 Thailand
    J Am Dent Assoc 137:1267-74. 2006
    ..The authors conducted a cross-sectional survey to assess headache disability in patients with orofacial pain...

Research Grants62

  1. AGE-RELATED CHANGE IN TRIGEMINAL GANGLION EXCITABILITY
    Thomas Baumann; Fiscal Year: 2003
    ..Trigeminal neuralgia is a severe, recurrent (episodic, but otherwise chronic) neuropathic facial pain syndrome that is rarely observed in children or young adults...
  2. Temporomandibular joint syndrome in females
    Nancy Berman; Fiscal Year: 2005
    ..In Specific Aim 3, we will examine the effects of ovarian steroids on TMJ and trigeminal responses to TMJ inflammation. These experiments will provide an innovative approach to the mechanism of hormonal regulation of facial pain.
  3. Pain Management in Temporomandibular Joint Disorders
    Jennifer Haythornthwaite; Fiscal Year: 2005
    ..Persons with persistent facial pain due to TMD for 3 months or longer will be enrolled in this randomized controlled study which incorporates a 2 ..
  4. Chronic Rhinosinusitis Integrative Studies Program (CRISP)
    Robert P Schleimer; Fiscal Year: 2013
    ..It involves inflammation of the paranasal sinuses that results in facial pain/pressure, nasal and sinus drainage, smell loss, and nasal obstruction...
  5. Coupling mechanisms of NOP receptors and calcium channels
    Victor Ruiz-Velasco; Fiscal Year: 2012
    ..Clinical studies have shown that SG blockade can be used to treat patients that suffer from chronic facial pain or headaches...
  6. Gene Therapy for Nerve Injury
    Luc Jasmin; Fiscal Year: 2010
    ..the sensory innervations of the face and find that this results in analgesia in rats with nerve injury induced facial pain. This is an encouraging indication a similar gene transfer strategy would provide pain relief to the many ..
  7. Civamide Nasal Spray for the Treatment of Postherpetic Neuralgia of the Trigemina
    Scott B Phillips; Fiscal Year: 2013
    ..Spray for the treatment of postherpetic neuralgia (PHN) of the trigeminal nerve [(TN), a severely disabling facial pain syndrome]...
  8. Molecular regulation of trigeminal sensory ganglia development
    Holger Knaut; Fiscal Year: 2013
    ..Malformations or injuries of the trigeminal sensory ganglion are associated with neuralgia, a recurrent facial pain condition. Despite its important role, very little is known about how the trigeminal sensory ganglion develops...
  9. Musculoskeletal Heritable Influences on Malocclusion
    James J Sciote; Fiscal Year: 2013
    ..asymmetry, which may affect occurrence of temporomandibular joint dysfunction that is a significant source of facial pain. Both findings indicate complex relationships between growth and function of muscular and skeletal components ..
  10. Glutamatergic transmission within the sensory ganglion
    Luc Jasmin; Fiscal Year: 2013
    ..dynamic area where key chemical phenomena are involved in various forms of pain, from migraines, to intractable facial pain, from fibromyalgia to chronic low back pain...
  11. Brain as a Research and Therapeutic Target in Chronic TMD
    Alexandre Dasilva; Fiscal Year: 2013
    ..direct current stimulation (tDCS), can provide after-effect modulatory results on acute and chronic facial pain measures by changing activity of those key structures, including the activation of the endogenous mu-opioid ..
  12. ACTIVITY OF VISCERAL & NOCICEPTIVE TRIGEMINAL NEURONS
    Andrew Strassman; Fiscal Year: 1992
    ..neurons with convergent viscerosomatic inputs may also be involved in mediating other types of cranial and facial pain by relaying afferent input from additional visceral and deep structures...
  13. Modulating Cortical and Sub-cortical Brain Circuits in Chronic Facial Pain
    Edward S Boyden; Fiscal Year: 2010
    Modulating Cortical and Sub-cortical Brain Circuits in Chronic Facial Pain Chronic pain, especially facial pain is difficult to treat because it is associated with an enormous diversity of nervous system alterations...
  14. MOLECULAR GENETICS OF SENSORY GANGLIA DEVELOPMENT
    Alexander Schier; Fiscal Year: 2007
    ..cosmetically devastating and are often associated with trigeminal neuralgia, a severe and recurrent neuropathic facial pain syndrome. Despite its important role, it is still poorly understood how the trigeminal ganglion develops...
  15. Intranasal nociceptin for the treatment of migraine and head pain
    JORDAN MECHANIC; Fiscal Year: 2009
    ..to concentrate in the trigeminal ganglia and reduce painful stimuli induced by migraine or other head or facial pain. Specific Aim 1 will determine the tissue and brain localization of [3H]N/OFQ after intranasal administration...
  16. NEUROENDOCRINOLOGY OF MASTICATORY MUSCLE DISORDERS
    Elizabeth Young; Fiscal Year: 2000
    ..group of conditions involving masticatory muscles and/or temporomandibular joints and characterized by chronic facial pain. The etiology and pathogenesis of TMDs are multifactorial, including a strong association with depression and ..
  17. Novel Treatment for the Relief of Chronic Orofacial Pain
    Richard Weiner; Fiscal Year: 2009
    ..Temporomandibular joint disorders (TMD) are one of the biggest segments of facial pain. Current methods of treating orofacial pain include drugs, prosthetic devices, and electrical stimulation...
  18. SCIENTIFIC CONGRESS ON OROFACIAL PAIN AND TMD
    James Fricton; Fiscal Year: 1993
    ..Chronic orofacial pain disorders are very common in the general population causing facial pain, earaches, headaches, and jaw dysfunction in nearly half of the population with about 5 to 10% have a problem ..
  19. BRAIN STEM MECHANISMS OF DEEP CRANIOFACIAL PAIN
    James Hu; Fiscal Year: 1993
    ....
  20. NEUROPHYSIOLOGY OF TRIGEMINAL NEURALGIA
    Thomas Baumann; Fiscal Year: 2002
    Trigeminal neuralgia is a severe, recurrent (episodic, but otherwise chronic) facial pain syndrome which affects chiefly older patients...
  21. OROFACIAL PAIN RESEARCH CENTER
    Glenn Clark; Fiscal Year: 1990
    ..DRI) at the UCLA School of Dentistry and will draw heavily upon the patients of the Temporomandibular and Facial Pain Clinic (TMFPC) in the School of Dentistry and the Pain Management Center (PMC) in the School of Medicine...
  22. RAGE, Inflammation and Temporomandibular Joint Disorders
    Regina Landesberg; Fiscal Year: 2006
    Disorders of the temporomandibular joint represent a common cause of facial pain. Although the precise etiology of TMD is yet to be fully elucidated, histological and arthroscopic studies suggest that especially at the late stages of ..
  23. Novel anesthetic mechanisms that desensitize nociceptors
    Lieju Liu; Fiscal Year: 2006
    ..capsaicin, the pungent compound in hot pepper, is used clinically to reduce pain arising from arthritis, oral facial pain, and even chronic pain...
  24. Trigeminal Neuralgia Association 5th National Conference
    Albert Rhoton; Fiscal Year: 2005
    ..Proposed presentation and discussion topics include: neuroanatomy of facial pain, neuropathic atypical facial pain, evaluating the hyperactivity of a cell's nucleus, medication management, non-..
  25. Brief Focused Treatment for TMD: Mechanisms of Action
    Mark Litt; Fiscal Year: 2007
    ..Men and women (N=106) with complaints of chronic facial pain for at least 3 months' duration will be recruited from the University Dental Clinics and from the ..
  26. MINNESOTA ORAL HEALTH CLINICAL RESEARCH CENTER
    Bruce Pihlstrom; Fiscal Year: 2000
    ..Center will focus on clinical research in periodontal diseases, dental materials and restorative science, oral facial pain, and oral facial and clinical genetics. Four core units are included in the Center...
  27. PSYCHOSOCIAL STRESS, BRUXISM, AND MYOFASCIAL TMD
    Karen Raphael; Fiscal Year: 2000
    ..who meet diagnostic criteria for myofascial TMD and who have had no prior treatment with oral appliances for facial pain. A group of 85 control subjects without any TMD will also be recruited from the non-TMD clinics at UMDNJ...
  28. World Workshop in Oral Medicine IV
    Peter Lockhart; Fiscal Year: 2005
    ..infections, (fungal and viral); Group 2: orai mucosal lesions (dysplasia and lichen planus); Group 3: oral, facial pain (neuropathic pain and burning mouth syndrome); Group 4: medically complex patients, (coagulopathy and HIV/AIDS) ..
  29. Oro-facial non Contact Thermal Stimulator
    MIKHAIL NEMENOV; Fiscal Year: 2006
    ..of the locations and properties of facial nociceptors is important for probing preclinical models of oro-facial pain and neuropathies and analgesic manipulations directed at the trigeminal system...
  30. Oral Health Disparities: Actions Taken About Pain
    Joseph Riley; Fiscal Year: 2007
    ..This information has important health policy implications for reducing the race and ethnic disparities in oral health through interventions that facilitate access to care and utilization of appropriate services. ..
  31. PARAFUNCTIONAL ACTIVITY AND TEMPOROMANDIBULAR DISORDERS
    Alan Glaros; Fiscal Year: 2002
    ....
  32. PERIPHERAL NMDA RECEPTORS AND TMD PAIN MECHANISMS
    Barry Sessle; Fiscal Year: 2006
    ..abstract_text> ..
  33. Hormonal Cycles in Women: Effects on Temporomandibular Disorder Pain & Symptoms
    Linda LeResche; Fiscal Year: 2008
    ..Thus, the proposed studies will provide important and unique information on the relationships of biological and psychosocial aspects of pain perception in women. [unreadable] [unreadable]..
  34. FIBROMYALGIA AND TMD IN YOUNG WOMEN-A MULTIRACIAL STUDY
    Octavia Plesh; Fiscal Year: 2001
    ..abstract_text> ..
  35. BIOBEHAVIORAL ETIOLOGY OF CHRONIC TEMPOROMANDIBULAR
    James Fricton; Fiscal Year: 2001
    ..Questionnaires will include RDC/TMD axis I and II, coping strategies questionnaire, a self report fibromyalgia screening form, and IMPATH. ..
  36. MENSTRUAL CYCLE EFFECTS ON TMD PAIN AND OTHER SYMPTOMS
    Linda LeResche; Fiscal Year: 2002
    ....
  37. Sensory Re-training following Orthognathic Surgery
    Ceib Phillips; Fiscal Year: 2005
    ..Our primary focus will be on the patient's perception of the negative impact of altered sensation on daily life. ..
  38. Brainstem Mechanisms of Craniofacial Muscle Pain
    JIN RO; Fiscal Year: 2006
    ..abstract_text> ..
  39. Developing Patient-Centered Measures for Outcomes of CAM Therapies
    Cheryl K Ritenbaugh; Fiscal Year: 2010
    ....
  40. Sex-Related Genetic Influences on Pain and Analgesia
    Roger Fillingim; Fiscal Year: 2009
    ....
  41. Advances in CAM Clinical Research Methodology
    Cheryl Ritenbaugh; Fiscal Year: 2002
    ..abstract_text> ..
  42. Preventing CVD in Native Populations: Traditional Living
    Cheryl Ritenbaugh; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  43. Toothache Pain: Sources of Care and Self-Remedies
    Leonard Cohen; Fiscal Year: 2005
    ..The instrument will be pretested on poor White, Black, Hispanic subjects (both individuals who sought relief from dentists and those who did not) who have experienced toothache pain during the preceding six months. ..
  44. PSYCHOSOCIAL INTERVENTIONS FOR SCLERODERMA
    Jennifer Haythornthwaite; Fiscal Year: 2003
    ..These findings will increase our understanding of the quality of life of individuals with scleroderma and determine whether self-help interventions can be used effectively to manage pain, depression, and distress about disfigurement. ..
  45. Biobehavioral Interventions in Pain Management
    Jennifer Haythornthwaite; Fiscal Year: 2006
    ....
  46. Molecular Targeting of the Vanilloid-1 Receptor
    JOHN NEUBERT; Fiscal Year: 2006
    ..These outcomes are expected to have significant positive effects on a wide spectrum of pain relating to tissue damage and injury. [unreadable] [unreadable]..
  47. Ethnic Differences in Responses to Painful Stimuli
    Roger Fillingim; Fiscal Year: 2006
    ..The results of this research will provide unique and important information regarding ethnic differences in pain responses. ..
  48. Choices: Family Physicians Treat Overweight Children
    Cheryl Ritenbaugh; Fiscal Year: 2006
    ..Children will be eligible for participation who are above the 90th percentile of BMI for age, and who can have the regular participation of at least one parent or guardian. [unreadable] [unreadable]..
  49. Center for Mind-Body Research
    Jennifer Haythornthwaite; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  50. Novel Operant Thermal Assessments of Orofacial Pain
    JOHN NEUBERT; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  51. Patient Visits to Physician Offices and/or Emergency Rooms for Dental Problems
    Leonard Cohen; Fiscal Year: 2007
    ..These issues will grow in importance with the aging of the population, as elderly individuals, in general, are more likely to visit a physician than a dentist. [unreadable] [unreadable] [unreadable]..
  52. Estrogenic LXR Alpha Response /Cholesterol Homeostasis
    Phillip Kramer; Fiscal Year: 2003
    ..abstract_text> ..
  53. PERIPHERAL CANNABINOIDS AND NEUROGENIC INFLAMMATION
    Kenneth Hargreaves; Fiscal Year: 2002
    ..This knowledge base may provide a rationale for developing peripherally-selective cannabinoid analgesics with minimal CNS-mediated side-effect liability. ..
  54. FIBROMYALGIA, DEPRESSION AND MYOFASCIAL TMD
    Karen Raphael; Fiscal Year: 2002
    ..If only FMS probands have familial M/TMD but M/TMD probands do not, this will support the 2nd hypothesis and indicate that the two disorders are provoked through different pathogenic processes. ..
  55. Comorbidity of Mental Disorders and Pain
    Robert Gatchel; Fiscal Year: 2008
    ..This Award will enable me to maintain the momentum and clinical research advances of two previous consecutive K02 awards from NIMH. ..
  56. EARLY DETECTION AND PREVENTION OF CHRONIC PAIN DISABILIT
    Robert Gatchel; Fiscal Year: 2003
    ..These 3 research projects will explore the efficacy of early identification of "high risk" acute patients in order to provide biobehavioral treatment intervention, while simultaneously evaluating cost-effectiveness. ..