Genomes and Genes
Summary: Pressure, burning, or numbness in the chest.
Publications365 found, 100 shown here
- Early diagnosis of myocardial infarction with sensitive cardiac troponin assaysTobias Reichlin
Department of Internal Medicine, University Hospital, Basel, Switzerland
N Engl J Med 361:858-67. 2009..The rapid and reliable diagnosis of acute myocardial infarction is a major unmet clinical need...
- Prognostic value of myeloperoxidase in patients with chest painMarie Luise Brennan
Department of Cell Biology, Cleveland Clinic Foundation, Cleveland 44195, USA
N Engl J Med 349:1595-604. 2003..Numerous lines of evidence suggest mechanistic links between myeloperoxidase and both inflammation and cardiovascular disease...
- High-sensitive cardiac troponin T outperforms novel diagnostic biomarkers in patients with acute chest painKai M Eggers
Department of Medical Sciences, Cardiology, Uppsala University, Uppsala, Sweden
Clin Chim Acta 413:1135-40. 2012Measurement of high-sensitive cardiac troponin (hs-cTn) has facilitated the early diagnostic assessment of chest pain patients...
- The health care burden of acute chest painS Goodacre
Heart 91:229-30. 2005
- ACCF/AHA 2007 clinical expert consensus document on coronary artery calcium scoring by computed tomography in global cardiovascular risk assessment and in evaluation of patients with chest pain: a report of the American College of Cardiology Foundation ClPhilip Greenland
Circulation 115:402-26. 2007
- Sensitive troponin I assay in early diagnosis of acute myocardial infarctionTill Keller
Department of Medicine II, University Medical Center, Johannes Gutenberg University, Mainz, Germany
N Engl J Med 361:868-77. 2009..Cardiac troponin testing is central to the diagnosis of acute myocardial infarction. We evaluated a sensitive troponin I assay for the early diagnosis and risk stratification of myocardial infarction...
- Review article: the burden of illness of non-cardiac chest painG D Eslick
Department of Medicine, The University of Sydney, Nepean Hospital, Penrith, NSW, Australia
Aliment Pharmacol Ther 16:1217-23. 2002Non-cardiac chest pain is a common condition affecting approximately one-quarter of the population during their lifetime, but the long-term economic costs of non-cardiac chest pain are poorly defined.
- Chest pain of cardiac and noncardiac originClaude Lenfant
National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, MD, USA
Metabolism 59:S41-6. 2010b>Chest pain is one of the most common symptoms driving patients to a physician's office or the hospital's emergency department...
- The association between emergency department crowding and adverse cardiovascular outcomes in patients with chest painJesse M Pines
Department of Emergency Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
Acad Emerg Med 16:617-25. 2009..The authors examined whether ED crowding was associated with adverse cardiovascular outcomes in patients with chest pain syndromes (chest pain or related complaints of possible cardiac origin).
- Effect of providing information about normal test results on patients' reassurance: randomised controlled trialKeith J Petrie
Department of Psychological Medicine, Faculty of Medical and Health Sciences, University of Auckland, Private Bag 92019, New Zealand
BMJ 334:352. 2007..To investigate whether providing information about normal findings before a diagnostic test improves patients' reassurance and reduces anxiety about symptoms...
- How useful are clinical features in the diagnosis of acute, undifferentiated chest pain?Steve Goodacre
Medical Care Research Unit, University of Sheffield, Sheffield, United Kingdom
Acad Emerg Med 9:203-8. 2002To measure the predictive value and diagnostic performance of clinical features used to diagnose coronary syndromes in patients presenting with acute, undifferentiated chest pain.
- Clinical value of diagnostic instruments for ruling out acute coronary syndrome in patients with chest pain: a systematic reviewJohann Steurer
Department of Internal Medicine, University of Zurich, Zurich, Switzerland
Emerg Med J 27:896-902. 2010Acute chest pain is a frequent reason to attend an emergency room, and various instruments for calculating the probability of an acute coronary syndrome exist.
- A method for improving arrival-to-electrocardiogram time in emergency department chest pain patients and the effect on door-to-balloon time for ST-segment elevation myocardial infarctionKevin M Takakuwa
Department of Emergency Medicine, Thomas Jefferson University Hospital, Philadelphia, PA, USA
Acad Emerg Med 16:921-7. 2009..to a door-to-electrocardiogram (ECG) time goal of 10 minutes or less for patients who presented to an ED with chest pain and the effect of this adherence on door-to-balloon (DTB) time for ST-segment elevation myocardial infarction (..
- Comparison of contemporary troponin assays with the novel biomarkers, heart fatty acid binding protein and copeptin, for the early confirmation or exclusion of myocardial infarction in patients presenting to the emergency department with chest painPaul Collinson
Department of Clinical Blood Sciences, St George s Hospital and Medical School, London, UK
Heart 100:140-5. 2014..To examine the diagnostic accuracy of novel biomarkers of myocardial injury and troponin assays for diagnosis of myocardial infarction...
- Coronary CT angiography versus standard evaluation in acute chest painUdo Hoffmann
Department of Radiology, Massachusetts General Hospital, Boston, MA 02114, USA
N Engl J Med 367:299-308. 2012..It is unclear whether an evaluation incorporating coronary computed tomographic angiography (CCTA) is more effective than standard evaluation in the emergency department in patients with symptoms suggestive of acute coronary syndromes...
- Effect of marriage on duration of chest pain associated with acute myocardial infarction before seeking careClare L Atzema
Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
CMAJ 183:1482-91. 2011..We aimed to determine whether marital status was a predictor of the duration of chest pain endured by patients with acute myocardial infarction before they sought care and whether the patient's sex ..
- Diagnostic accuracy of the TIMI risk score in patients with chest pain in the emergency department: a meta-analysisErik P Hess
Department of Emergency Medicine, Division of Emergency Medicine Research, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
CMAJ 182:1039-44. 2010..We sought to expand the clinical application of the TIMI risk score by assessing its prognostic accuracy in patients in the emergency department with potential acute coronary syndromes...
- Copeptin does not add diagnostic information to high-sensitivity troponin T in low- to intermediate-risk patients with acute chest pain: results from the rule out myocardial infarction by computed tomography (ROMICAT) studyMahir Karakas
Department of Internal Medicine II Cardiology, University of Ulm Medical Center, Ulm, Germany
Clin Chem 57:1137-45. 2011..sought to evaluate the predictive value of copeptin and its incremental value beyond that of high-sensitivity cardiac troponin T (hs-cTnT) in patients with acute chest pain and low to intermediate risk for acute coronary syndrome (ACS).
- Combined copeptin and troponin to rule out myocardial infarction in patients with chest pain and a history of coronary artery diseasePatrick Ray
Department of Emergency Medicine, Pitie Salpetriere Hospital, Assistance Publique Hopitaux de Paris AP HP, INSERM UMRS 956, Universite Pierre et Marie Curie Paris 6, 75013, Paris, France
Am J Emerg Med 30:440-8. 2012..was to evaluate the additional value of copeptin to conventional cardiac troponin (cTn) for a rapid ruling out of acute myocardial infarction (AMI) in patients with acute chest pain and a previous history of coronary artery disease (CAD).
- Application of the TIMI risk score for unstable angina and non-ST elevation acute coronary syndrome to an unselected emergency department chest pain populationCharles V Pollack
Department of Emergency Medicine, Pennsylvania Hospital, University of Pennsylvania Health System, Philadelphia, PA, USA
Acad Emerg Med 13:13-8. 2006Patients presenting with chest pain or related symptoms suggestive of myocardial ischemia, without ST-segment elevation (NSTE) on their presenting electrocardiograms, often present a diagnostic challenge in the emergency department (ED)...
- Relation between coronary artery calcium and incident chest pain in a community-dwelling screening populationAllen J Taylor
Cardiology Service, Walter Reed Army Medical Center, Washington, DC, USA
Am J Cardiol 96:61-3. 2005Incident chest pain occurred in 30.3% of 1,743 asymptomatic healthy men and women who were followed for up to 4 years...
- Detecting acute coronary syndrome in the emergency department with cardiac magnetic resonance imagingRaymond Y Kwong
Laboratory of Cardiac Energetics, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD 20892 1061, USA
Circulation 107:531-7. 2003Managing chest pain in the emergency department remains a challenge with current diagnostic strategies. We hypothesized that cardiac MRI could accurately identify patients with possible or probable acute coronary syndrome.
- Chest wall pain and rib fracture after stereotactic radiotherapy for peripheral non-small cell lung cancerJon Paul J Voroney
Department of Radiation Oncology, Tom Baker Cancer Centre Alberta, Canada
J Thorac Oncol 4:1035-7. 2009..The median dose to rib fracture sites was 46 to 50 Gy, depending on the method of dose calculation. We describe a typical case of poststereotactic radiotherapy rib fracture and present dosimetric analysis of patients with rib fracture...
- Women's early warning symptoms of acute myocardial infarctionJean C McSweeney
College of Nursing, University of Arkansas for Medical Sciences, 4301 W Markham St, Slot 529, Little Rock, AR 72205, USA
Circulation 108:2619-23. 2003..Data remain sparse on women's prodromal symptoms before acute myocardial infarction (AMI). This study describes prodromal and AMI symptoms in women...
- The diagnostic accuracy of 64-slice computed tomography coronary angiography compared with stress nuclear imaging in emergency department low-risk chest pain patientsMichael J Gallagher
Department of Cardiology, William Beaumont Hospital, Royal Oak, MI 48073, USA
Ann Emerg Med 49:125-36. 2007We compared the accuracy of multidetector computed tomography (CT) coronary angiography with stress nuclear imaging for the detection of an acute coronary syndrome or 30-day major adverse cardiac events in low-risk chest pain patients.
- Validation of a brief observation period for patients with cocaine-associated chest painJim Edward Weber
Departments of Emergency Medicine, University of Michigan, Ann Arbor, and Hurley Medical Center, Flint, Mich, USA
N Engl J Med 348:510-7. 2003Retrospective studies of patients with cocaine-associated chest pain suggest that a strategy of discharging patients from the emergency department after a 12-hour observation period if they do not have evidence of ischemia should be ..
- Chest pain in general practice: incidence, comorbidity and mortalityAna Ruigómez
Centro Español de Investigación Farmacoepidemiológica CEIFE, Madrid, Spain
Fam Pract 23:167-74. 2006b>Chest pain is a common symptom that presents the primary care physician with a complex diagnostic and therapeutic challenge.
- Diagnostic value of high sensitive troponin T in chest pain patients with no persistent ST-elevationsDina Melki
Section of Cardiology, Department of Medicine, Karolinska University Hospital, Huddinge Karolinska Institutet, Stockholm, Sweden
Scand Cardiovasc J 45:198-204. 2011..The aim of this study was to compare the early diagnostic value of the Roche high-sensitive troponin T (Hs-TnT) and that of conventional troponins...
- A 2-h diagnostic protocol to assess patients with chest pain symptoms in the Asia-Pacific region (ASPECT): a prospective observational validation studyMartin Than
Christchurch Hospital, Christchurch, New Zealand
Lancet 377:1077-84. 2011Patients with chest pain contribute substantially to emergency department attendances, lengthy hospital stay, and inpatient admissions...
- A clinical prediction rule for early discharge of patients with chest painJim Christenson
The Center for Health Evaluation and Outcome Sciences, University of British Columbia, St Paul s Hospital, Vancouver, British Columbia, Canada
Ann Emerg Med 47:1-10. 2006....
- Response of unexplained chest pain to proton pump inhibitor treatment in patients with and without objective evidence of gastro-oesophageal reflux diseasePeter J Kahrilas
Northwestern University, Feinberg School of Medicine, Chicago, IL 60611 2951, USA
Gut 60:1473-8. 2011Unexplained chest pain is potentially attributable to gastro-oesophageal reflux disease (GORD) or oesophageal motility disorders. Reflux chest pain may occur without heartburn...
- Door-to-ECG time in patients with chest pain presenting to the EDDeborah B Diercks
Division of Emergency Medicine, University of California, Davis Medical Center, Sacramento, 95817, USA
Am J Emerg Med 24:1-7. 2006..To describe time to electrocardiogram (ECG) acquisition, identify factors associated with timely acquisition, and evaluate the influence of time to ECG on adverse clinical outcomes...
- A 2-hour diagnostic protocol for possible cardiac chest pain in the emergency department: a randomized clinical trialMartin Than
Emergency Department, Christchurch Hospital, Christchurch, New Zealand
JAMA Intern Med 174:51-8. 2014Patients with chest pain represent a high health care burden, but it may be possible to identify a patient group with a low short-term risk of adverse cardiac events who are suitable for early discharge.
- Prospective validation of the Thrombolysis in Myocardial Infarction Risk Score in the emergency department chest pain populationMaureen Chase
Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104 4283, USA
Ann Emerg Med 48:252-9. 2006..To validate the use of the TIMI risk score in the ED, we prospectively assess its potential utility in a broad ED chest pain patient population.
- Myeloperoxidase is not useful for the early assessment of patients with chest painKai M Eggers
Department of Medical Sciences, Cardiology, Uppsala University Hospital and Uppsala Clinical Research Center, Uppsala, Sweden
Clin Biochem 43:240-5. 2010Myeloperoxidase (MPO) has been listed as a potentially useful risk marker in acute coronary syndrome. However, its clinical utility in patients with acute chest pain is not yet defined.
- The role of myeloperoxidase (MPO) for prognostic evaluation in sensitive cardiac troponin I negative chest pain patients in the emergency departmentJulia Searle
Department of Cardiology, CVK and Emergency Medicine CVK, CCM, Charite Universitatsmedizin Berlin, Germany
Eur Heart J Acute Cardiovasc Care 2:203-10. 2013The diagnostic work-up of patients with acute chest pain in the emergency department (ED) is a challenging task. Serial troponin testing is required to rule-out acute myocardial infarction.
- Chest pain and ischaemic heart disease in primary careS Nilsson
Department of General Practice and Primary Care, Faculty of Health Sciences, University of Linkoping, Sweden
Br J Gen Pract 53:378-82. 2003b>Chest pain is the main symptom of first presentation with ischaemic heart disease (IHD). Little is known about the incidence of IHD among patients consulting the general practitioner (GP) for chest pain.
- Prognostic value of CT angiography for major adverse cardiac events in patients with acute chest pain from the emergency department: 2-year outcomes of the ROMICAT trialChristopher L Schlett
Cardiac MR PET CT Program, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
JACC Cardiovasc Imaging 4:481-91. 2011The aim of this study was to determine the 2-year prognostic value of cardiac computed tomography (CT) for predicting major adverse cardiac events (MACE) in patients presenting to the emergency department (ED) with acute chest pain.
- Anxiety and hypervigilance to cardiopulmonary sensations in non-cardiac chest pain patients with and without psychiatric disordersKamila S White
University of Missouri Saint Louis, Department of Psychology, Saint Louis, MO 63121, USA
Behav Res Ther 48:394-401. 2010..vigilance, cardiac anxiety, and the mediating role of interoceptive fear on pain in patients with non-cardiac chest pain (NCCP; a syndrome of chest pain in the absence of identifiable organic etiology)...
- Chest wall syndrome in primary care patients with chest pain: presentation, associated features and diagnosisStefan Bösner
Department of General Practice Family Medicine, University of Marburg, D 35043 Marburg, Germany
Fam Pract 27:363-9. 2010Chest wall syndrome (CWS) is the most frequent aetiology of chest pain in a primary care setting.
- The Chest Pain Choice trial: a pilot randomized trial of a decision aid for patients with chest pain in the emergency departmentMeghan A Pierce
Knowledge and Encounter Research Unit, Mayo Clinic, Rochester, Minnesota, USA
Trials 11:57. 2010b>Chest pain is a common presenting complaint in the emergency department (ED)...
- Risk prediction in patients presenting with suspected cardiac pain: the GRACE and TIMI risk scores versus clinical evaluationG Ramsay
Cardiovascular Research, Division of Medical and Radiological Sciences, The University of Edinburgh, Chancellors Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK
QJM 100:11-8. 2007Identifying which patients presenting with undifferentiated chest pain are at risk of major cardiac events is a major clinical challenge...
- Very early diagnosis of chest pain by point-of-care testing: comparison of the diagnostic efficiency of a panel of cardiac biomarkers compared with troponin measurement alone in the RATPAC trialPaul Collinson
Department of Clinical Blood Sciences, St George s Hospital, Ground Floor, Jenner Wing, London SW17 0QT, UK
Heart 98:312-8. 2012..To assess the impact of triple marker testing on patient management and the diagnostic efficiencies of different biomarker strategies examined...
- Psychologic morbidity and health-related quality of life of patients assessed in a chest pain observation unitS Goodacre
Northern General Hospital, Sheffield, United Kingdom
Ann Emerg Med 38:369-76. 2001We sought to measure psychologic morbidity and health-related quality of life among patients attending the hospital with acute chest pain both at presentation and 1 month after rigorous assessment for cardiac disease.
- Heart fatty acid-binding protein offers similar diagnostic performance to high-sensitivity troponin T in emergency room patients presenting with chest painKenji Inoue
Department of Cardiology, Juntendo University Nerima Hospital, Tokyo, Japan
Circ J 75:2813-20. 2011....
- Prognostic value of a multimarker approach for patients presenting to hospital with acute chest painConor J McCann
The Heart Centre, Royal Victoria Hospital, Belfast, United Kingdom
Am J Cardiol 103:22-8. 2009..the prognostic role of novel biomarkers for the risk stratification of patients admitted with ischemic-type chest pain, a prospective study of 664 patients presenting to 2 coronary care units with ischemic-type chest pain was ..
- Detailed angiographic analysis of women with suspected ischemic chest pain (pilot phase data from the NHLBI-sponsored Women's Ischemia Syndrome Evaluation [WISE] Study Angiographic Core Laboratory)B L Sharaf
Rhode Island Hospital, Brown University, Providence, Rhode Island 02903, USA
Am J Cardiol 87:937-41; A3. 2001..series of women enrolled in the Women's Ischemia Syndrome Evaluation (WISE) study who had suspected ischemic chest pain. Previous studies have suggested that women with chest pain have a lower prevalence of significant coronary ..
- Risk prediction with serial myeloperoxidase monitoring in patients with acute chest painStephen J Nicholls
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA
Clin Chem 57:1762-70. 2011..Although myeloperoxidase (MPO) monitoring is predictive for cardiovascular outcomes in suspected acute coronary syndromes, the value of serial testing is unknown...
- The prevalence and correlates of psychological outcomes in patients with acute non-cardiac chest pain: a systematic reviewRosemary Webster
Department of Psychology, University of Sheffield, Western Bank, Sheffield S10 2TN, UK
Emerg Med J 29:267-73. 2012Over 40% of patients admitted to emergency departments (ED) with chest pain receive a non-cardiac diagnosis...
- Chest pain presenting to the Emergency Department--to stratify risk with GRACE or TIMI?Richard Lyon
Department of Emergency Medicine, Royal Infirmary, Little France Crescent, Old Dalkeith Road, Edinburgh EH16 4SA, United Kingdom
Resuscitation 74:90-3. 2007..is a need to stratify risk rapidly in patients presenting to the Emergency Department (ED) with undifferentiated chest pain. The Global Registry of Acute Coronary Events (GRACE) and the Thrombolysis in Myocardial Infarction (TIMI) ..
- Randomised controlled trial and economic evaluation of a chest pain observation unit compared with routine careSteve Goodacre
School of Health and Related Research, University of Sheffield, Sheffield S1 4DA
BMJ 328:254. 2004To measure the effectiveness and cost effectiveness of providing care in a chest pain observation unit compared with routine care for patients with acute, undifferentiated chest pain.
- Diagnostic and prognostic utility of early measurement with high-sensitivity troponin T assay in patients presenting with chest painSally J Aldous
Christchurch Hospital, Christchurch, New Zealand
CMAJ 184:E260-8. 2012..High-sensitivity troponin assays are now available for clinical use. We investigated whether early measurement with such an assay is superior to a conventional assay in the evaluation of acute coronary syndromes...
- Chest pain in the emergency department: the broad spectrum of causesD C Knockaert
Department of Internal Medicine, Gasthuisberg University Hospital, Leuven, Belgium
Eur J Emerg Med 9:25-30. 2002We performed a prospective study to describe the broad spectrum of causes of chest pain in patients presenting to the emergency department and to compare the diagnoses in referred patients, self-referred patients and patients rushed in by ..
- Value and limitations of chest pain history in the evaluation of patients with suspected acute coronary syndromesClifford J Swap
Massachusetts General Hospital, Boston, MA 02114, USA
JAMA 294:2623-9. 2005The chest pain history, physical examination, determination of coronary artery disease (CAD) risk factors, and the initial electrocardiogram compose the information immediately available to clinicians to help determine the probability of ..
- Functional esophageal disordersJean Paul Galmiche
University of Nantes, Nantes, France
Gastroenterology 130:1459-65. 2006Functional esophageal disorders represent processes accompanied by typical esophageal symptoms (heartburn, chest pain, dysphagia, globus) that are not explained by structural disorders, histopathology-based motor disturbances, or ..
- Chest pain in focal musculoskeletal disordersMette Jensen Stochkendahl
Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Campusvej 55, DK 5230 Odense M, Denmark
Med Clin North Am 94:259-73. 2010The musculoskeletal system is a recognized source of chest pain. However, despite the apparently benign origin, patients with musculoskeletal chest pain remain under-diagnosed, untreated, and potentially continuously disabled in terms of ..
- Investigation of paramedics' compliance with clinical practice guidelines for the management of chest painKen Figgis
Emergency Department, Mayo General Hospital, Castlebar, Mayo, UK
Emerg Med J 27:151-5. 2010..However, previous studies have indicated that paramedics' compliance with chest pain protocols is suboptimal and that many patients do not receive the benefits of appropriate prehospital treatment.
- Morbidity of DSM-IV Axis I disorders in patients with noncardiac chest pain: Psychiatric morbidity linked with increased pain and health care utilizationKamila S White
University of Missouri Saint Louis, Department of Psychology, Saint Louis, MO 63121, USA
J Consult Clin Psychol 76:422-30. 2008The present study examined current and lifetime psychiatric morbidity, chest pain, and health care utilization in 229 patients with noncardiac chest pain (NCCP), angina-like pain in the absence of cardiac etiology...
- Cardiac and psychiatric diagnoses among patients referred for chest pain and palpitationsEgil Jonsbu
Department of Psychiatry, Molde Hospital, Molde, Norway
Scand Cardiovasc J 43:256-9. 2009The purpose of this study was to assess the prevalence of cardiac and psychiatric diagnoses in patients with chest pain and palpitations.
- Non-cardiac chest pain: predictors of health care seeking, the types of health care professional consulted, work absenteeism and interruption of daily activitiesG D Eslick
Department of Medicine, The University of Sydney, Nepean Hospital, Penrith, New South Wales, Australia
Aliment Pharmacol Ther 20:909-15. 2004To determine the predictors of health care seeking, assess the types of health care professional consulted and to calculate the work absenteeism rates and interruptions to daily activities among non-cardiac chest pain patients.
- Use of a whole blood rapid panel test for heart-type fatty acid-binding protein in patients with acute chest pain: comparison with rapid troponin T and myoglobin testsYoshihiko Seino
First Department of Medicine and Coronary Care Unit, Nippon Medical School, Tokyo, Japan
Am J Med 115:185-90. 2003..We sought to determine the clinical utility of a newly developed qualitative test to measure heart-type fatty acid-binding protein levels in blood for the early identification of myocardial infarction...
- Relationship between low lymphocyte count and major cardiac events in patients with acute chest pain, a non-diagnostic electrocardiogram and normal troponin levelsJulio Nunez
Servicio de Cardiologia, Hospital Clinico Universitario, Universitat de Valencia, Avda Blasco Ibanez 17, Valencia, Spain
Atherosclerosis 206:251-7. 2009Risk stratification of patients with acute chest pain, non-diagnostic electrocardiogram and normal troponin (ACPneg) remains a challenge, partly because no standardized set of biomarkers with prognostic ability has been identified in this ..
- The association of diabetes and older age with the absence of chest pain during acute coronary syndromesHolli A DeVon
Loyola University Chicago, USA
West J Nurs Res 30:130-44. 2008..Patients with diabetes comprised 33.2% of the sample and reported significantly less chest pain and more unusual fatigue...
- Psychological treatments for noncardiac chest pain: recommendations for a new approachJeanne L Esler
Centers for Behavioral and Preventive Medicine, Miriam Hospital, Brown University Medical School, Coro Building, Suite 500, 1 Hoppin Street, Providence, RI 02903, USA
J Psychosom Res 56:263-9. 2004..Our objective is to describe the current state of treatment for NCCP, identify barriers to treatment and limitations of current approaches, and to recommend treatment strategies, which may address these challenges...
- Errors of omission in the treatment of prehospital chest pain patientsJon C Rittenberger
University of Pittsburgh Affiliated Residency in Emergency Medicine and the Department of Emergency Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
Prehosp Emerg Care 9:2-7. 2005..sought to assess the frequency and nature of deviations from a standardized treatment protocol for the chief complaint of chest pain. They also sought to quantify any time delays in treatment of potential ischemic cardiac chest pain.
- Chest pain in primary care: epidemiology and pre-work-up probabilitiesStefan Bösner
Department of General Practice Family Medicine, University of Marburg, Marburg, Germany
Eur J Gen Pract 15:141-6. 2009b>Chest pain is a common complaint and reason for consultation. We aimed to study the epidemiology of chest pain with respect to underlying aetiologies and to establish pre-work-up probabilities for the primary care setting.
- A neural computational aid to the diagnosis of acute myocardial infarctionWilliam G Baxt
Department of Emergency Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA 19104 4283, USA
Ann Emerg Med 39:366-73. 2002..presence of acute myocardial infarction in adult patients who present to the emergency department with anterior chest pain remains elusive...
- Coronary computed tomographic angiography and risk of all-cause mortality and nonfatal myocardial infarction in subjects without chest pain syndrome from the CONFIRM Registry (coronary CT angiography evaluation for clinical outcomes: an international multIksung Cho
Division of Cardiology, Severance Cardiovascular Hospital, Seoul, South Korea
Circulation 126:304-13. 2012The predictive value of coronary computed tomographic angiography (cCTA) in subjects without chest pain syndrome (CPS) has not been established...
- 2-Hour accelerated diagnostic protocol to assess patients with chest pain symptoms using contemporary troponins as the only biomarker: the ADAPT trialMartin Than
Christchurch Hospital, Christchurch, New Zealand
J Am Coll Cardiol 59:2091-8. 2012The purpose of this study was to determine whether a new accelerated diagnostic protocol (ADP) for possible cardiac chest pain could identify low-risk patients suitable for early discharge (with follow-up shortly after discharge).
- Comparative diagnostic yield and 3-month outcomes of "triple rule-out" and standard protocol coronary CT angiography in the evaluation of acute chest painRyan D Madder
Department of Cardiovascular Medicine, William Beaumont Hospital, 3601 W 13 Mile Road, Royal Oak, MI 48073, USA
J Cardiovasc Comput Tomogr 5:165-71. 2011..Triple rule-out" CT angiography simultaneously evaluates coronary artery disease, pulmonary embolism, and aortic dissection in a single imaging examination. However, the clinical outcomes of this approach are unknown...
- Considerations for early acute myocardial infarction rule-out for emergency department chest pain patients: the case of copeptinGiuseppe Lippi
U O Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliera di Parma, Parma, Italy
Clin Chem Lab Med 50:243-53. 2012The evaluation of patients admitted at the emergency department (ED) for chest pain is challenging and involves many different clinical specialists including emergency physicians, laboratory professionals and cardiologists...
- Experimental pain and psychologic status of patients with chest pain with normal coronary arteries or ischemic heart diseaseR Zachariae
Institute of Psychology, Aarhus University, Aarhus, Denmark
Am Heart J 142:63-71. 2001BACKGROUND: The cause of chest pain in patients with a normal coronary angiogram (NCA) remains an enigma. Also, it is unclear whether psychosocial factors play a role in the etiology of chest pain in these patients...
- Time distribution of the onset of chest pain in subjects with acute ST-elevation myocardial infarction: an eight-year, single-center study in ChinaEn Zhi Jia
Department of Cardiovascular Medicine, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, China
PLoS ONE 7:e32478. 2012The objective of this study was to explore the time distribution patterns of the onset of chest pain in subjects with acute ST-elevation myocardial infarction in a Chinese population.
- Differentiating ST-elevation myocardial infarction from nonischemic ST-elevation in patients with chest painViet Tran
Department of Medicine, Section of Cardiology, Baylor College of Medicine, Houston, Texas, USA
Am J Cardiol 108:1096-101. 2011..Broad inconsistencies existed among readers as to the chosen reasons for NISTE classification. In conclusion, we found wide variations in experienced interventional cardiologists in differentiating STEMI with a need for pPCI from NISTE...
- Patients with noncardiac chest pain and benign palpitations referred for cardiac outpatient investigation: a 6-month follow-upEgil Jonsbu
Department of Psychiatry, Molde Hospital, 6407 Molde, Norway
Gen Hosp Psychiatry 32:406-12. 2010The aims were to (a) study the characteristics and outcome in patients with noncardiac chest pain or benign palpitations referred for cardiac evaluation, (b) compare psychological characteristics in the two groups, (c) identify predictors ..
- The independent association of anxiety with non-cardiac chest painLoes Smeijers
a Department of Medical and Clinical Psychology, Center of Research on Psychology in Somatic diseases CoRPS, Tilburg University, The Netherlands
Psychol Health 29:253-63. 2014Non-cardiac chest pain (NCCP) is common in clinical cardiology. Anxiety is an important factor in NCCP because of its role in the neurobehavioural processes of pain regulation...
- Relation between peripheral vascular endothelial function and coronary flow reserve in patients with chest pain and normal coronary angiogramChul Soo Park
Int J Cardiol 113:118-20. 2006..the intima-media thickness (IMT) of the carotid artery in 32 subjects (mean age 58+/-9 years, M/F=9:23 ) with chest pain and normal coronary angiogram. The subjects were divided into 2 groups according to CFR >or=2.1 or <2...
- Heart rate variability risk score for prediction of acute cardiac complications in ED patients with chest painMarcus Eng Hock Ong
Department of Emergency Medicine, Singapore General Hospital, Outram Road, Singapore 169608
Am J Emerg Med 31:1201-7. 2013..a risk score incorporating heart rate variability (HRV) and traditional vital signs for the prediction of early mortality and complications in patients during the initial presentation to the emergency department (ED) with chest pain.
- The effect of an empirical trial of high-dose lansoprazole on symptom response of patients with non-cardiac chest pain--a randomized, double-blind, placebo-controlled, crossover trialJ Bautista
The Neuro Enteric Clinical Research Group, Section of Gastroenterology, Department of Medicine, Southern Arizona VA Health Care System, 3601 S 6th Avenue, Tucson, AZ 85723, USA
Aliment Pharmacol Ther 19:1123-30. 2004Empirical trial with high-dose omeprazole has been shown to be a sensitive tool for diagnosing patients with gastro-oesophageal reflux disease-related non-cardiac chest pain.
- Growth differentiation factor-15 in the early diagnosis and risk stratification of patients with acute chest painNora Schaub
Department of Internal Medicine, University Hospital, Basel, Switzerland
Clin Chem 58:441-9. 2012..Growth differentiation factor-15 (GDF-15) is a stress-responsive marker that might aid in the early diagnosis and risk stratification of patients with suspected acute myocardial infarction (AMI)...
- A simple score for predicting coronary artery disease in patients with chest painE B Wu
Cardiothoracic Centre, Guy s and St Thomas Hospitals, London
QJM 98:803-11. 2005We have previously derived a chest pain score by comparing those with and without coronary artery disease on angiography, which was subsequently validated in patients attending coronary angiography.
- Social and gender variation in the prevalence, presentation and general practitioner provisional diagnosis of chest painH Richards
Department of General Practice, University of Glasgow, 4 Lancaster Crescent, Glasgow G12 ORR
J Epidemiol Community Health 54:714-8. 2000To describe the prevalence of Rose angina and non-exertional chest pain in men and women in socioeconomically contrasting areas; to describe the proportions of men and women who present with the symptom of chest pain and who receive a ..
- Treatment needs of patients admitted for acute chest painR A Mayou
Department of Psychiatry, Warneford Hospital, University of Oxford, UK
J Psychosom Res 53:1177-83. 2002To examine the characteristics, subsequent resource use and outcome of a consecutive cohort of admissions with acute chest pain not due to myocardial infarction.
- Stress CMR imaging observation unit in the emergency department reduces 1-year medical care costs in patients with acute chest pain: a randomized study for comparison with inpatient careChadwick D Miller
Department of Emergency Medicine, Wake Forest School of Medicine, Winston Salem, North Carolina 27357, USA
JACC Cardiovasc Imaging 4:862-70. 2011..direct cost of medical care and clinical events during the first year after patients with intermediate risk acute chest pain were randomized to stress cardiac magnetic resonance (CMR) observation unit (OU) testing versus inpatient care.
- Low-risk patients with chest pain in the emergency department: negative 64-MDCT coronary angiography may reduce length of stay and hospital chargesJanet M May
Department of Radiology, University of Washington School of Medicine, 1959 NE Pacific St, RR210, Box 357115, Seattle, WA 98195, USA
AJR Am J Roentgenol 193:150-4. 2009The current standard-of-care workup of low-risk patients with chest pain in an emergency department takes 12-36 hours and is expensive...
- PAPP-A as a marker of increased long-term risk in patients with chest painPeter A Kavsak
Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada
Clin Biochem 42:1012-8. 2009..The present study examined whether PAPP-A measured in an emergency department (ED) chest pain population in association with conventional and novel high sensitivity cTn (hs-cTnI) assays can predict long-..
- Severe coronary tortuosity or myocardial bridging in patients with chest pain, normal coronary arteries, and reversible myocardial perfusion defectsNicola Gaibazzi
Division of Cardiology, Parma University Hospital, Italy
Am J Cardiol 108:973-8. 2011..angiograms enrolled in the SPAM contrast stress echocardiographic diagnostic study in which 400 patients with chest pain syndrome of suspected cardiac origin with a clinical indication to coronary angiography were enrolled...
- Coronary computed tomography angiography for early triage of patients with acute chest pain: the ROMICAT (Rule Out Myocardial Infarction using Computer Assisted Tomography) trialUdo Hoffmann
Cardiac MR PET CT Program, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts 02114, USA
J Am Coll Cardiol 53:1642-50. 2009This study was designed to determine the usefulness of coronary computed tomography angiography (CTA) in patients with acute chest pain.
- Evaluation of symptom index in identifying gastroesophageal reflux disease-related noncardiac chest painRoy Dekel
Section of Gastroenterology, Department of Medicine, Southern Arizona VA Health Care System and University of Arizona Health Science Center, 3601 S 6th Avenue, Tucson, AZ 85723, USA
J Clin Gastroenterol 38:24-9. 2004..lt;4), has been suggested as a measure to improve diagnosis of gastroesophageal reflux (GER)-related noncardiac chest pain (NCCP)...
- Cost-effectiveness of coronary computed tomography and cardiac stress imaging in the emergency department: a decision analytic model comparing diagnostic strategies for chest pain in patients at low risk of acute coronary syndromesVirginia L Priest
Centre for Applied Health Economics, School of Medicine, Griffith University, Brisbane, Queensland, Australia
JACC Cardiovasc Imaging 4:549-56. 2011Emergency department presentations with chest pain are expensive and often unrelated to coronary artery disease (CAD)...
- Usefulness of 64-slice multidetector computed tomography as an initial diagnostic approach in patients with acute chest painSung A Chang
Division of Cardiology, Cardiovascular Center, Seoul National University Bundang Hospital, Seoul, Republic of Korea
Am Heart J 156:375-83. 2008..However, the role of MDCT as part of the initial diagnostic for evaluating acute chest pain is less well established.
- Costochondritis: diagnosis and treatmentAnne M Proulx
Wright State University Boonshoft School of Medicine, Dayton, Ohio, USA
Am Fam Physician 80:617-20. 2009..is usually self-limited and benign, it should be distinguished from other, more serious causes of chest pain. Coronary artery disease is present in 3 to 6 percent of adult patients with chest pain and chest wall ..
- Accuracy of general practitioners' assessment of chest pain patients for coronary heart disease in primary care: cross-sectional study with follow-upStefan Bösner
Department of General Practice Family Medicine, University of Marburg, D 35043 Marburg, Germany
Croat Med J 51:243-9. 2010To estimate how accurately general practitioners' (GP) assessed the probability of coronary heart disease in patients presenting with chest pain and analyze the patient management decisions taken as a result.
- Emergency department and office-based evaluation of patients with chest painMichael C Kontos
Department of Internal Medicine, Cardiology Division, Virginia Commonwealth University, Richmond, USA
Mayo Clin Proc 85:284-99. 2010The management of patients with chest pain is a common and challenging clinical problem...
- Cost-effectiveness of coronary CT angiography versus myocardial perfusion SPECT for evaluation of patients with chest pain and no known coronary artery diseaseJames K Min
Departments of Medicine and Radiology, Weill Medical College of Cornell University and The New York Presbyterian Hospital, 520 E 70th St, Room K415, New York, NY 10021, USA
Radiology 254:801-8. 2010To evaluate the cost-effectiveness of diagnostic strategies for individuals with chest pain without known coronary artery disease (CAD) in the Assessment by Coronary Computed Tomographic Angiography of Individuals Undergoing Invasive ..
- Chest wall syndrome among primary care patients: a cohort studyFrançois Verdon
Department of Ambulatory Care and Community Medicine, University of Lausanne, Lausanne, Switzerland
BMC Fam Pract 8:51. 2007The epidemiology of chest pain differs strongly between outpatient and emergency settings. In general practice, the most frequent cause is the chest wall pain...
- Usefulness of computed tomographic coronary angiography in patients with acute chest pain with and without high-risk featuresBenjamin J W Chow
Department of Medicine, University of Ottawa Heart Institute, Ottawa, Ontario, Canada
Am J Cardiol 106:463-9. 2010..tomographic coronary angiography (CTA) and its ability to direct revascularization in patients with acute chest pain syndrome (ACPS) was investigated...
- Chest pain, palpitations and panicR Mayou
University Department of Psychiatry, Warneford Hospital, Oxford, UK
J Psychosom Res 44:53-70. 1998b>Chest pain and palpitations are commonly described in the general population and are frequent presenting symptoms in all medical settings...
- High-risk chief complaints I: chest pain--the big threeKar mun C Woo
Department of Emergency Medicine, Boston Medical Center, Dowling 1 South, 1 Boston Medical Center Place, Boston, MA 02118, USA
Emerg Med Clin North Am 27:685-712, x. 2009b>Chest pain is one of the most frequently seen chief complaints in patients presenting to emergency departments, and is considered to be a "high-risk" chief complaint...
- Negative ECG-gated cardiac CT in patients with low-to-moderate risk chest pain in the emergency department: 1-year follow-upWilliam P Shuman
Department of Radiology, University of Washington School of Medicine, Seattle, WA 98195, USA
AJR Am J Roentgenol 195:923-7. 2010..of this article is to determine the frequency of adverse cardiac events during the year following a negative cardiac CT angiogram in a population of patients presenting to the emergency department with low-to-moderate risk chest pain.
- Accuracy of symptoms and signs for coronary heart disease assessed in primary careStefan Bösner
Department of General Practice Family Medicine, University of Marburg, Germany
Br J Gen Pract 60:e246-57. 2010Diagnosing the aetiology of chest pain is challenging. There is still a lack of data on the diagnostic accuracy of signs and symptoms for acute coronary events in low-prevalence settings.
- Chymase-Mediated MMP Activation in Ishemia Reperfusion InjuryLOUIS JOSEPH DELL'ITALIA; Fiscal Year: 2013..This prompt response to the onset of chest pain coupled with the widespread use of statins and other drugs have reversed the incidence of ST elevation/nonST ..
- Novel Biomarkers in Aortic Aneurysms and Acute Aortic DissectionJENNIFER E contact VAN EYK; Fiscal Year: 2010..patients with known aortic aneurysms (ii) facilitate diagnosis of aortic dissection in the patient with acute chest pain and (iii) helps us to individualize therapy...
- Surgical Revascularization's Impact on Mitochondria in Hibernating MyocardiumROSEMARY FRANCES KELLY; Fiscal Year: 2013..PUBLIC HEALTH RELEVANCE: Patients with episodic chest pain prior to a heart attack suffer less damage to the heart than individuals presenting with the same type of heart ..
- Excitability of afferents evoking the exercise pressor reflexVictor Ruiz-Velasco; Fiscal Year: 2013..In hearts whose coronary arteries are narrowed by disease, this vasoconstriction can cause chest pain and fatal arrhythmias...
- Computer Simulation of Acute Coronary Syndrome Care in the Emergency DepartmentDANIEL JOSEPH FRANCE; Fiscal Year: 2010..b>Chest pain prompts over 5...
- Molecular Imaging of Ischemic Memory with Ultrasound - Transition to HumansJonathan R Lindner; Fiscal Year: 2010..In patients who present with acute or recent chest pain but who have a non-diagnostic ECG, it may be possible to improve and expedite the diagnosis of acute coronary ..
- The Fat1 Cadherin in Atherosclerotic Vascular DiseaseNICHOLAS E SIBINGA; Fiscal Year: 2013..atherosclerosis, vascular obstruction, and impaired blood flow, and lead to such very common diseases as angina (chest pain), heart failure, stroke, limb loss due to impaired circulation, and death...
- Role of the TRPV1 channel in myocardial salvage from ischemia-reperfusion injuryERIC RICHARD GROSS; Fiscal Year: 2012..This may suggest that the chest pain (angina) actually is a natural pathway to protect from heart attack injury...
- PROMISE Trial: Clinical Coordinating CenterPamela Susan Douglas; Fiscal Year: 2013DESCRIPTION (provided by applicant): Millions of Americans develop chest pain suggestive of coronary heart disease each year and often require non-invasive diagnostic testing...
- PROMISE Trial: EQOL Coordinating CenterDaniel B Mark; Fiscal Year: 2013DESCRIPTION (provided by applicant): Millions of Americans develop chest pain suggestive of coronary heart disease each year and often require non-invasive diagnostic testing...
- PROMISE Trial: SDCCKerry L Lee; Fiscal Year: 2013DESCRIPTION (provided by applicant): Millions of Americans develop chest pain suggestive of coronary heart disease each year and often require non-invasive diagnostic testing...
- Metabolic Profiling of Acute Myocardial Injury in HumansGREGORY DYER LEWIS; Fiscal Year: 2012..diagnostic utility of these novel metabolic biomarkers in patients presenting to the emergency department with chest pain. Specific Aim 4 will be to extend metabolic profiling beyond ischemia to identify metabolic modulators of ..
- Solutions for Vertigo presentations in the Emergency Department (SOLVE) ProjectKEVIN ANTHONY KERBER; Fiscal Year: 2012..Dizziness presentations are different from other common diagnostic dilemmas (e.g., chest pain and headache presentations) because no laboratory, electrophysiological, or neuro-imaging test is a valid and ..
- Genesis of Esophageal Pain: Longitudinal Muscle Spasm and Wall IschemiaRavinder K Mittal; Fiscal Year: 2013DESCRIPTION (provided by applicant): Seventy percent of patients coming to the emergency room with chest pain have normal coronary arteries and thus have non-cardiac pain. Esophagus is suspected to be the cause of pain in these patients...
- ROMICAT II - CCC - Lead ApplicationUdo Hoffmann; Fiscal Year: 2013This application represents the Clinical Coordinating Center of the overall proposal. Patients with acute chest pain and normal or non-diagnostic electrocardiograms (ECGs) represent a cohort whose management is notably inefficient and ..
- Rule-Out Myocardial Infarction Using Computed Assisted Tomography-ROMICATII,DCCDAVID ALAN SCHOENFELD; Fiscal Year: 2012This application represents the Clinical Coordinating Center of the overall proposal. Patients with acute chest pain and normal or non-diagnostic electrocardiograms (ECGs) represent a cohort whose management is notably inefficient and ..
- PROMISE Trial: Dx CoreUdo Hoffmann; Fiscal Year: 2013
- Stents and Antiplatelet Drugs: Impact on Ischemia and Bleeding in the ElderlySamip Vasaiwala; Fiscal Year: 2011..conventional technique in both the emergency setting of a heart attack as well as more routine therapy to reduce chest pain. In general, there are two types of coronary stents: drug-coated (or drug-eluting stents, DES) and non-drug- ..
- Spinal glia activation in chronic stress-induced visceral hyperalgesiaSylvie Bradesi; Fiscal Year: 2013..may be generalized to many other stress-sensitive pain conditions, including interstitial cystitis, non-cardiac chest pain and fibromyalgia...
- Discovery &Application of Proteomics-Based Biomarkers of Early Myocardial InjuryMarc S Sabatine; Fiscal Year: 2012..Second, we examine whether measurement of the biomarkers in patients presenting to the Emergency Department with chest pain improves our ability to discriminate between non-ischemic chest pain versus unstable angina...
- CMR-IMPACTCHADWICK DAVID MILLER; Fiscal Year: 2013..goal, we propose a clinical trial (n=312) involving emergency department patients with intermediate to high-risk chest pain and detectable to minimally elevated serum troponin within 6 hours of evaluation...
- Metabolomic Biomarkers of Early Myocardial InjuryMarc S Sabatine; Fiscal Year: 2013..Second, we examine whether measurement of the biomarkers in patients presenting to the Emergency Department with chest pain improves our ability to discriminate between non-ischemic chest pain versus unstable angina...
- Ultrasound-Targeted Therapy for Acute Myocardial InfarctionSanjiv Kaul; Fiscal Year: 2013..24 hr a day call, the chances of opening an infarct-related artery (IRA) within 90-120 minutes of the onset of chest pain is 85%...
- The mechanics of symptom generation in dysphagiaJohn E Pandolfino; Fiscal Year: 2013..proposal focuses on the relationship between IBP and EGJ compliance as it relates to symptoms of dysphagia and chest pain. Thus, the goals of this proposal are:1) to define the physiologic relationship between IBP and EGJ compliance, ..
- Non-invasive detection of heart transplant rejection with MRINEIL RANJAN CHATTERJEE; Fiscal Year: 2013..Because heart transplant patients lack innervation of the heart, they do not experience the chest pain usually associated with infarct allowing CAV to progress un- noticed...
- ESOPHAGEAL MOTOR FUNCTION IN HEALTH AND DISEASEREZA NONE SHAKER; Fiscal Year: 2012..such as those found in non-erosive reflux disease (NERD), functional heartburn (FH) and pain in non-cardiac chest pain (NCCP) poses a significant clinical challenge...
- PROMISE Trial: Substudy to Assess for Effective Dose of RadiationANDREW EINSTEIN; Fiscal Year: 2013DESCRIPTION (provided by applicant): Millions of Americans develop chest pain suggestive of coronary artery disease (CAD) each year and often receive non-invasive diagnostic testing such as myocardial perfusion scintigraphy (MPS) or, ..
- Fractional flow reserve measurement based on coronary angiographic imagesSABEE Y MOLLOI; Fiscal Year: 2010..stenosis), where angiography is very limited in distinguishing whether a coronary lesions is the cause of chest pain. Because of the major limitations of standard coronary arteriography, a method for functional measure of ..
- Cardiovascular Imaging in Ischemic Heart DiseaseUdo Hoffmann; Fiscal Year: 2013..in the Framingham Heart Study, 2) Comparing Competing Diagnostic Strategies to Triage Patients with Acute Chest Pain in the ED - A Randomized Diagnostic Multicenter Trial with the major goal to determine whether cardiac CT is ..
- Cardiovascular Regenerative MedicineDOUGLAS EUGENE VAUGHAN; Fiscal Year: 2013..in patients with chronic, refractory ischemia: patients with intractable angina had significant reductions in chest pain and improved exercise tolerance, while patients with critical limb ischemia had reduced amputation rates...
- Esophageal Mast Cell Nerve InteractionsShaoyong Yu; Fiscal Year: 2013Abnormal esophageal sensations, such as esophageal-related noncardiac chest pain and heartburn, are common complaints. The underlying mechanism of such esophageal nociception remains unclear...
- MVPS: Health Concerns, Role function, Health Service UseKRISTINE SCORDO; Fiscal Year: 2002..Anecdotal reports by individuals with MVPS indicate a variety of frightening symptoms, including chest pain, shortness of breath, palpitations, migraine headaches, lightheadedness, fatigue, dizziness on standing, mood ..
- Targeted Nanoparticles of Bismuth Organo Complexes for Spectral CT Imaging of CorY Andrew Wang; Fiscal Year: 2013DESCRIPTION (provided by applicant): Chest pain in patients presenting to the emergency department (ED) present a clinical dilemma: transfer for emergent coronary revascularization, admit overnight for cardiac telemetry and stress ..
- FACSVantage SE UpgradeRAYMOND HESTER; Fiscal Year: 2004..10) role of activated leukocyte cell adhesion molecule and activated monocytes in the pathogenesis of acute chest pain, 11) role of erythrocyte-endothelial cell adhesion in acute lung injury in sickle cell disease, 12) chrondrocyte ..
- PAIN AND BETA-ENDORPHIN RESPONSES IN MEN AND WOMENDavid Sheps; Fiscal Year: 2001..in patients with stable angina, and in individuals without evidence of coronary artery disease and no chest pain. The following specific aims will be tested: (1) Women will exhibit greater sensitivity to thermal, ischemic, ..
- Multi-analyte Biosensor for Emerging Cardiac MarkersCHARLES PENNINGTON; Fiscal Year: 2001..researchers and physicians to improve evaluation and triage of patients reporting to emergency departments with chest pain. New point-of-care diagnostic technologies designed for rapid quantification of conventional markers including, ..
- DIAGNOSIS OF CHEST PAIN AND CARE IN RURAL HOSPITALSJohn Westfall; Fiscal Year: 2000..abstract_text> ..
- Improved MR Techniques for Coronary Artery ImagingCraig H Meyer; Fiscal Year: 2010..These new methods are designed to detect and evaluate coronary artery disease, which causes chest pain and heart attacks...
- GDNF in the Enteric Nervous SystemYun Xia; Fiscal Year: 2007..nervous system that may be manifest as the irritable bowel syndrome (IBS), nonulcer dyspepsia or non-cardiac chest pain. The research is directed to understanding the role of glial derived neurotropic factor (GDNF) in the enteric ..
- Development of Platelet & Coagulation Activation AssaysRONALD SHEBUSKI; Fiscal Year: 2001..e. emergency room/chest pain unit) if the patient is indeed experiencing a thrombus-dependent acute myocardial infarct...
- ASSESSING THE VARIABILITY IN TIME TO TREATMENT IN SURGERMark Chassin; Fiscal Year: 2001..g., time from injury to hospital; time from onset of chest pain to emergency room door)...
- TREE-STRUCTURED STATISTICAL METHODSRichard Olshen; Fiscal Year: 1993..patients who enter the emergency room with chief complaint of acute chest pain. Particular improvements and new capabilities to existing algorithms include but are not limited to time series ..
- CARDIAC PROCEDURE USE: A PROSPECTIVE COHORT STUDYPaula Johnson; Fiscal Year: 1999..the appropriateness and necessity of cardiac procedures for a cohort of 3,400 patients presenting with acute chest pain in an emergency department...
- NOVEL ESOPHAGEAL MOTOR FUNCTION ASSESSMENT SYSTEMJianFeng Chen; Fiscal Year: 2006..Typical esophageal motor disorders include dysphasia, gastroesophageal reflux disease (GERD), non-cardiac chest pain, etc...
- MECHANISMS OF ACTIVATION OF CARDIAC NOCICEPTORSHui Lin Pan; Fiscal Year: 2005..role of ET-1 and prostaglandins in activation of cardiac nociceptors and elaborating the perception of chest pain in patients with myocardial ischemia...
- ANXIETY, DEPRESSION, AND NONCARDIAC CHEST PAINFrancis Keefe; Fiscal Year: 2005APPLICANT'S DESCRIPTION: Persistent pain is a significant problem for many non-cardiac chest pain patients...
- HEART ATTACK SURVIVAL KIT PROJECTMickey Eisenberg; Fiscal Year: 2003..Also unique is the inclusion of an aspirin in the kit. Data on 911 calls for chest pain and self-administration of aspirin will be collected from the medical incident report forms (MIRF), completed by ..
- New ECG Criteria for Posterior Myocardial InfarctionShu Fen Wung; Fiscal Year: 2004..Currently, standard 12-lead ECGs are obtained on all patients presenting to the ED with chest pain. The 12-lead ECG has been useful in the diagnosis of acute anterior and inferior MI's, however standard 12-leads ..
- Sequist:Can Risk Score Alerts Improve Office Care for Chest Pain?THOMAS SEQUIST; Fiscal Year: 2009The evaluation of ambulatory patients with chest pain is a challenging and serious problem, accounting for a significant proportion of all outpatient visits...
- COMPLEMENT AND LEUKOCYTES IN MYOCARDIAL INFARCTIONROGER ROSSEN; Fiscal Year: 1991..frequently detected in sera of patients with myocardial infarction but only rarely in sera of controls who have chest pain without infarction...
- IMPROVED VASODILATORS FOR PHARMACOLOGICAL STRESS IMAGINGGeorge Beller; Fiscal Year: 2000..Currently used agents, adenosine or dipyridamole, cause a significant number of adverse side effects including chest pain, A-V conduction block, hypotension, and bronchospasm...
- SMOKING CESSATION IN THE CHEST PAIN OBSERVATION UNITBeth Bock; Fiscal Year: 2002Approximately 4.5 million Americans visit the emergency department each year with symptoms of chest pain. Over 90% are eventually ruled out for myocardial infarction and other acute cardiovascular events...
- Detection of cardiac ischemia using magnetocardiographyMARK DIIORIO; Fiscal Year: 2007..b>Chest pain is the second leading cause of admission in emergency rooms in the U...
- PSYCHOPHYSIOLOGICAL INTERACTIONS--NON-CARDIAC CHEST PAINLAURENCE BRADLEY; Fiscal Year: 2001Approximately 75,000-150,000 patients each year in the United States are identified as suffering from chest pain of unknown etiology (CP)...
- OUTCOMES OF MANAGEMENT STRATEGIES FOR CHEST PAINThomas Lee; Fiscal Year: 1993..These analyses will provide important insights into the impact of different mangement strategies on patient outcomes and resource utilization...
- Prediction of Cardiomyopathy in Type I Diabetes by MRSGerald Pohost; Fiscal Year: 2007..decrease in cardiac phosphocreatine (PCr)/ATP with handgrip stress, indicative of ischemia, in women with chest pain but no artery disease. The most likely explanation for these results was the presence of microvascular disease...
- Integrated Myocardial Ischemia Assessment with MRIJohn Pauly; Fiscal Year: 2006Patients with chest pain suffer from inadequate blood supply to the heart. This "myocardial ischemia" is reflected in changes in many physiologic parameters, including coronary flow reserve and myocardial contractile reserve...
- PATIENT-CENTERED CARE AND MYOCARDIAL INFARCTION OUTCOMESAllen Fremont; Fiscal Year: 2002..during hospitalization had worse self-reported health status and were more likely than other patients to report chest pain 1 year after their AMI...
- Tc-99m Glucarate for chest pain triage in emergency room.KOON PAK; Fiscal Year: 2009Differentiating acute coronary syndrome (ACS) from noncardiac chest pain is the primary diagnostic challenge for clinicians in the emergency department...
- IMMUNOPATHWAYS IN ACUTE CORONARY SYNDROMESCornelia Weyand; Fiscal Year: 2005..develop acute coronary syndromes and to risk-stratify patients presenting in the emergency room with acute onset chest pain. The clinical significance of these two specific aims stems from the potential to identify a novel prognostic ..
- EPIDEMIOLOGY OF CORONARY HEART DISEASE IN BLACKSLucile Adams Campbell; Fiscal Year: 1992..S. blacks. Among patients with acute myocardial infarction who often present with typical ischemic chest pain, it has been shown that blacks present more often without cheat pain when compared to whites and hispanics...
- GENDER DIFFERENCES IN PATTERNS OF CHRONIC ANGINAL PAINLaura Kimble; Fiscal Year: 2001..symptom experience including how patterns of angina change over time, the effect of gender on patterns of chest pain, and relationships among gender, patterns of chest pain and quality of life...