low back pain

Summary

Summary: Acute or chronic pain in the lumbar or sacral regions, which may be associated with musculo-ligamentous SPRAINS AND STRAINS; INTERVERTEBRAL DISK DISPLACEMENT; and other conditions.

Top Publications

  1. pmc Chapter 4. European guidelines for the management of chronic nonspecific low back pain
    O Airaksinen
    Eur Spine J 15:S192-300. 2006
  2. pmc Burden of major musculoskeletal conditions
    Anthony D Woolf
    Peninsula Medical School, Duke of Cornwall Department of Rheumatology, Royal Cornwall Hospital, Truro TR1 3LJ, England
    Bull World Health Organ 81:646-56. 2003
  3. ncbi A systematic review of the global prevalence of low back pain
    Damian Hoy
    University of Queensland, Herston, Queensland, Australia
    Arthritis Rheum 64:2028-37. 2012
  4. ncbi A systematic review of low back pain cost of illness studies in the United States and internationally
    Simon Dagenais
    Division of Orthopaedic Surgery and Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada
    Spine J 8:8-20. 2008
  5. ncbi Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale
    J T Farrar
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Blockley Hall, Room 816, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Pain 94:149-58. 2001
  6. pmc Comparison of stratified primary care management for low back pain with current best practice (STarT Back): a randomised controlled trial
    Jonathan C Hill
    Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Stoke on Trent, UK
    Lancet 378:1560-71. 2011
  7. ncbi Non-specific low back pain
    Federico Balagué
    Department of Rheumatology, Physical Medicine, and Rehabilitation, Hôpital Fribourgeois Hôpital cantonal, Fribourg and Geneva University, Geneva, Switzerland
    Lancet 379:482-91. 2012
  8. ncbi Diagnosis and treatment of low back pain: a joint clinical practice guideline from the American College of Physicians and the American Pain Society
    Roger Chou
    Oregon Health and Science University, Portland, Oregon, USA
    Ann Intern Med 147:478-91. 2007
  9. pmc An updated overview of clinical guidelines for the management of non-specific low back pain in primary care
    Bart W Koes
    Department of General Practice, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Eur Spine J 19:2075-94. 2010
  10. ncbi painDETECT: a new screening questionnaire to identify neuropathic components in patients with back pain
    Rainer Freynhagen
    Klinik fur Anasthesiologie, Universitatsklinikum Dusseldorf, Dusseldorf, Germany
    Curr Med Res Opin 22:1911-20. 2006

Detail Information

Publications302 found, 100 shown here

  1. pmc Chapter 4. European guidelines for the management of chronic nonspecific low back pain
    O Airaksinen
    Eur Spine J 15:S192-300. 2006
  2. pmc Burden of major musculoskeletal conditions
    Anthony D Woolf
    Peninsula Medical School, Duke of Cornwall Department of Rheumatology, Royal Cornwall Hospital, Truro TR1 3LJ, England
    Bull World Health Organ 81:646-56. 2003
    ..the burden of four major musculoskeletal conditions: osteoarthritis, rheumatoid arthritis, osteoporosis, and low back pain. Osteoarthritis, which is characterized by loss of joint cartilage that leads to pain and loss of function ..
  3. ncbi A systematic review of the global prevalence of low back pain
    Damian Hoy
    University of Queensland, Herston, Queensland, Australia
    Arthritis Rheum 64:2028-37. 2012
    To perform a systematic review of the global prevalence of low back pain, and to examine the influence that case definition, prevalence period, and other variables have on prevalence.
  4. ncbi A systematic review of low back pain cost of illness studies in the United States and internationally
    Simon Dagenais
    Division of Orthopaedic Surgery and Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada
    Spine J 8:8-20. 2008
    The economic burden of low back pain (LBP) is very large and appears to be growing. It is not possible to impact this burden without understanding the strengths and weaknesses of the research on which these costs are calculated.
  5. ncbi Clinical importance of changes in chronic pain intensity measured on an 11-point numerical pain rating scale
    J T Farrar
    Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Blockley Hall, Room 816, 423 Guardian Drive, Philadelphia, PA 19104, USA
    Pain 94:149-58. 2001
    ..placebo-controlled clinical trials of pregabalin in diabetic neuropathy, postherpetic neuralgia, chronic low back pain, fibromyalgia, and osteoarthritis were used...
  6. pmc Comparison of stratified primary care management for low back pain with current best practice (STarT Back): a randomised controlled trial
    Jonathan C Hill
    Arthritis Research UK Primary Care Centre, Primary Care Sciences, Keele University, Stoke on Trent, UK
    Lancet 378:1560-71. 2011
    ..We compared the clinical effectiveness and cost-effectiveness of stratified primary care (intervention) with non-stratified current best practice (control)...
  7. ncbi Non-specific low back pain
    Federico Balagué
    Department of Rheumatology, Physical Medicine, and Rehabilitation, Hôpital Fribourgeois Hôpital cantonal, Fribourg and Geneva University, Geneva, Switzerland
    Lancet 379:482-91. 2012
    Non-specific low back pain has become a major public health problem worldwide...
  8. ncbi Diagnosis and treatment of low back pain: a joint clinical practice guideline from the American College of Physicians and the American Pain Society
    Roger Chou
    Oregon Health and Science University, Portland, Oregon, USA
    Ann Intern Med 147:478-91. 2007
    ..1: Clinicians should conduct a focused history and physical examination to help place patients with low back pain into 1 of 3 broad categories: nonspecific low back pain, back pain potentially associated with radiculopathy ..
  9. pmc An updated overview of clinical guidelines for the management of non-specific low back pain in primary care
    Bart W Koes
    Department of General Practice, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Eur Spine J 19:2075-94. 2010
    ..this study was to present and compare the content of (inter)national clinical guidelines for the management of low back pain. To rationalise the management of low back pain, evidence-based clinical guidelines have been issued in many ..
  10. ncbi painDETECT: a new screening questionnaire to identify neuropathic components in patients with back pain
    Rainer Freynhagen
    Klinik fur Anasthesiologie, Universitatsklinikum Dusseldorf, Dusseldorf, Germany
    Curr Med Res Opin 22:1911-20. 2006
    ..As low back pain (LBP) patients constitute an important subgroup of chronic pain patients, we addressed the following issues: (..
  11. ncbi Low back pain
    Anthony Delitto
    School of Health and Rehabilitation Sciences, University of Pittsburgh, Pennsylvania, USA
    J Orthop Sports Phys Ther 42:A1-57. 2012
    ..The purpose of these low back pain clinical practice guidelines, in particular, is to describe the peer-reviewed literature and make ..
  12. ncbi The Epidemiology of low back pain
    D Hoy
    University of Queensland, School of Population Health, Herston Rd, Herston, QLD 4006, Australia
    Best Pract Res Clin Rheumatol 24:769-81. 2010
    b>Low back pain is an extremely common problem that most people experience at some point in their life...
  13. ncbi One-year results of a randomized, double-blind, active controlled trial of fluoroscopic caudal epidural injections with or without steroids in managing chronic discogenic low back pain without disc herniation or radiculitis
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 14:25-36. 2011
    ..to be the subject of research and debate as discogenic pain is increasingly seen as a cause of non-specific low back pain. Among non-surgical methods used to manage chronic low back pain with or without disc herniation, epidural ..
  14. ncbi Systematic review: strategies for using exercise therapy to improve outcomes in chronic low back pain
    Jill A Hayden
    Institute for Work and Health and University of Toronto, Toronto, Ontario, Canada
    Ann Intern Med 142:776-85. 2005
    Exercise therapy encompasses a heterogeneous group of interventions. There continues to be uncertainty about the most effective exercise approach in chronic low back pain.
  15. ncbi Acupuncture in patients with chronic low back pain: a randomized controlled trial
    Benno Brinkhaus
    Institute of Social Medicine, Epidemiology, and Health Economics, Charite, University Medical Center, Berlin, Germany
    Arch Intern Med 166:450-7. 2006
    Acupuncture is widely used by patients with low back pain, although its effectiveness is unclear. We investigated the efficacy of acupuncture compared with minimal acupuncture and with no acupuncture in patients with chronic low back pain.
  16. ncbi The burden of chronic low back pain: clinical comorbidities, treatment patterns, and health care costs in usual care settings
    Mugdha Gore
    Avalon Health Solutions, Inc, Philadelphia, PA 19102, USA
    Spine (Phila Pa 1976) 37:E668-77. 2012
    ..Retrospective analysis of an insurance claims database...
  17. ncbi Guideline warfare over interventional therapies for low back pain: can we raise the level of discourse?
    Roger Chou
    Department of Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR 97239, USA
    J Pain 12:833-9. 2011
    ....
  18. ncbi The association between obesity and low back pain: a meta-analysis
    Rahman Shiri
    Centre of Expertise for Health and Work Ability, Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, Helsinki, Finland
    Am J Epidemiol 171:135-54. 2010
    This meta-analysis assessed the association between overweight/obesity and low back pain. The authors systematically searched the Medline (National Library of Medicine, Bethesda, Maryland) and Embase (Elsevier, Amsterdam, the Netherlands)..
  19. ncbi German Acupuncture Trials (GERAC) for chronic low back pain: randomized, multicenter, blinded, parallel-group trial with 3 groups
    Michael Haake
    Orthopaedic Department, University of Regensburg, Bad Abbach, Germany
    Arch Intern Med 167:1892-8. 2007
    To our knowledge, verum acupuncture has never been directly compared with sham acupuncture and guideline-based conventional therapy in patients with chronic low back pain.
  20. ncbi 'Listen to me, tell me': a qualitative study of partnership in care for people with non-specific chronic low back pain
    Susan Carolyn Slade
    School of Primary Health Care, Faculty of Medicine, Nursing and Health Sciences, Box Hill, Victoria, Australia
    Clin Rehabil 23:270-80. 2009
    To investigate and summarize participant experience of exercise programmes for non-specific chronic low back pain and the effects of these experiences on exercise participation and engagement.
  21. ncbi Evaluating common outcomes for measuring treatment success for chronic low back pain
    Jens R Chapman
    Department of Orthopaedic Surgery, Harborview Medical Center, Seattle, WA, USA
    Spine (Phila Pa 1976) 36:S54-68. 2011
    ..Systematic review...
  22. ncbi Real-world practice patterns, health-care utilization, and costs in patients with low back pain: the long road to guideline-concordant care
    Jasmina I Ivanova
    Analysis Group, Inc, New York, NY 10020, USA
    Spine J 11:622-32. 2011
    Treatment guidelines suggest that most acute low back pain (LBP) episodes substantially improve within a few weeks and that immediate use of imaging and aggressive therapies should be avoided.
  23. ncbi Illness perceptions of low back pain patients in primary care: what are they, do they change and are they associated with outcome?
    Nadine E Foster
    Primary Care Musculoskeletal Research Centre, Primary Care Sciences Building, Keele University, North Staffordshire ST5 5BG, Keele, UK
    Pain 136:177-87. 2008
    We describe the illness perceptions of patients with low back pain, how they change over 6 months, and their associations with clinical outcome...
  24. pmc Low back pain: what is the long-term course? A review of studies of general patient populations
    Lise Hestbaek
    The Backcenter, Ringe Hospital, Odense University Hospital, 5950 Ringe, Denmark
    Eur Spine J 12:149-65. 2003
    It is often claimed that up to 90% of low back pain (LBP) episodes resolve spontaneously within 1 month...
  25. ncbi Low back pain
    R A Deyo
    Department of Medicine, and Center for Cost and Outcomes Research, University of Washington, Seattle 98195, USA
    N Engl J Med 344:363-70. 2001
  26. ncbi A systematic review and meta-analysis of yoga for low back pain
    Holger Cramer
    Department of Complementary and Integrative Medicine, University of Duisburg Essen, Essen, Germany
    Clin J Pain 29:450-60. 2013
    To systematically review and meta-analyze the effectiveness of yoga for low back pain.
  27. pmc The prognosis of acute and persistent low-back pain: a meta-analysis
    Lucíola da C Menezes Costa
    George Institute For Global Health, The University of Sydney, Sydney, Australia
    CMAJ 184:E613-24. 2012
    ..Our secondary objective was to investigate whether pain and disability have similar courses...
  28. pmc Is insufficient quantity and quality of sleep a risk factor for neck, shoulder and low back pain? A longitudinal study among adolescents
    Juha P Auvinen
    Finnish Institute of Occupational Health, Aapistie 1, 90220 Oulu, Finland
    Eur Spine J 19:641-9. 2010
    ..At the same time, the prevalence of neck, shoulder and low back pain has increased...
  29. pmc Sickness absence and concurrent low back and neck-shoulder pain: results from the MUSIC-Norrtälje study
    Teresia Nyman
    Department of Occupational and Environmental Health, Stockholm County Council, Norrbacka, 171 76, Stockholm, Sweden
    Eur Spine J 16:631-8. 2007
    ..The study also implies that spinal co-morbidity is an important factor to be considered by clinicians and occupational health providers in planning treatment, or in prevention of these disorders...
  30. pmc A randomized trial comparing acupuncture, simulated acupuncture, and usual care for chronic low back pain
    Daniel C Cherkin
    Center for Health Studies, 1730 Minor Avenue, Seattle, WA 98101, USA
    Arch Intern Med 169:858-66. 2009
    ..This trial addresses the importance of needle placement and skin penetration in eliciting acupuncture effects for patients with chronic low back pain.
  31. pmc A systematic review on the effectiveness of physical and rehabilitation interventions for chronic non-specific low back pain
    Marienke van Middelkoop
    Department of General Practice, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Eur Spine J 20:19-39. 2011
    b>Low back pain (LBP) is a common and disabling disorder in western society. The management of LBP comprises a range of different intervention strategies including surgery, drug therapy, and non-medical interventions...
  32. ncbi Effective treatment of chronic low back pain in humans reverses abnormal brain anatomy and function
    David A Seminowicz
    Alan Edwards Centre for Research on Pain, McGill Scoliosis and Spine Research Group, McGill University, Montreal, Quebec H3A 1A4, Canada
    J Neurosci 31:7540-50. 2011
    ..We acquired MRI scans from chronic low back pain (CLBP) patients before (n = 18) and 6 months after (spine surgery or facet joint injections; n = 14) treatment...
  33. ncbi Graded exposure in vivo in the treatment of pain-related fear: a replicated single-case experimental design in four patients with chronic low back pain
    J W Vlaeyen
    Institute for Rehabilitation Research, Hoensbroek, The Netherlands
    Behav Res Ther 39:151-66. 2001
    ..to usual graded activity in reducing pain-related fears, catastrophising and pain disability in chronic low back pain patients reporting substantial fear of movement/(re)injury...
  34. ncbi The rising prevalence of chronic low back pain
    Janet K Freburger
    The Cecil G Sheps Center for Health Services Research, The University of North Carolina at Chapel Hill, 725 Martin Luther King Jr Blvd, Chapel Hill, NC 27599 7590, USA
    Arch Intern Med 169:251-8. 2009
    National or state-level estimates on trends in the prevalence of chronic low back pain (LBP) are lacking...
  35. ncbi How important are back pain beliefs and expectations for satisfactory recovery from back pain?
    Chris J Main
    Arthritis Research Campaign National Primary Care Centre, Keele University, N Staffs, UK, ST5 5BG, United Kingdom
    Best Pract Res Clin Rheumatol 24:205-17. 2010
    ..The article concludes with a summary of the key messages for clinical management of patients presenting with painful conditions and suggestions for further research...
  36. ncbi Responsiveness of the numeric pain rating scale in patients with low back pain
    John D Childs
    Department of Physical Therapy, Wilford Hall Medical Center, San Antonio, TX, USA
    Spine (Phila Pa 1976) 30:1331-4. 2005
    Cohort study of patients with low back pain (LBP) receiving physical therapy.
  37. ncbi A randomized controlled trial comparing 2 types of spinal manipulation and minimal conservative medical care for adults 55 years and older with subacute or chronic low back pain
    Maria A Hondras
    Palmer Center for Chiropractic Research, Davenport, Iowa 52803, USA
    J Manipulative Physiol Ther 32:330-43. 2009
    Chiropractic care is used by many older patients for low back pain (LBP), but there are no published results of randomized trials examining spinal manipulation (SM) for older adults...
  38. ncbi Characterizing the course of low back pain: a latent class analysis
    Kate M Dunn
    Primary Care Sciences Research Centre, Keele University, Keele, United Kingdom
    Am J Epidemiol 163:754-61. 2006
    ..Identification of four distinct groups of patients improves understanding of the course of back pain and may provide a basis of classification for intervention...
  39. ncbi Results of the prospective, randomized, multicenter Food and Drug Administration investigational device exemption study of the ProDisc-L total disc replacement versus circumferential fusion for the treatment of 1-level degenerative disc disease
    Jack Zigler
    Texas Back Institute Texas Health Research Institute, Plano, TX 75093, USA
    Spine (Phila Pa 1976) 32:1155-62; discussion 1163. 2007
    ..A prospective, randomized, multicenter, Food and Drug Administration-regulated Investigational Device Exemption clinical trial...
  40. ncbi Early identification and management of psychological risk factors ("yellow flags") in patients with low back pain: a reappraisal
    Michael K Nicholas
    Pain Management Research Institute, University of Sydney at Royal North Shore Hospital, St Leonards, New South Wales, Australia
    Phys Ther 91:737-53. 2011
    ..that arise from this development: (1) Can yellow flags influence outcomes in people with acute or subacute low back pain? and (2) Can yellow flags be targeted in interventions to produce better outcomes? Consistent evidence has ..
  41. pmc The acceptability of acupuncture for low back pain: a qualitative study of patient's experiences nested within a randomised controlled trial
    Ann Hopton
    Department of Health Sciences, University of York, York, North Yorkshire, United Kingdom
    PLoS ONE 8:e56806. 2013
    ..This study used patient interviews following acupuncture treatment for back pain to identify, understand and describe the elements that contribute or detract from acceptability of treatment...
  42. ncbi Exercise for the primary, secondary and tertiary prevention of low back pain in the workplace: a systematic review
    Julie Ann Bell
    Centre for Research into Disability and Society, School of Occupational Therapy and Social Work, Curtin University of Technology, GPO Box U1987, Perth, WA, 6845, Australia
    J Occup Rehabil 19:8-24. 2009
    b>Low back pain (LBP) is one of the most costly conditions to manage in occupational health. Individuals with chronic or recurring LBP experience difficulties returning to work due to disability...
  43. ncbi Comparing the Pilates method with no exercise or lumbar stabilization for pain and functionality in patients with chronic low back pain: systematic review and meta-analysis
    Ligia M Pereira
    MSc Programme in Physical Education, Universidade Estadual de Londrina UEM, Londrina, Brazil
    Clin Rehabil 26:10-20. 2012
    To perform a systematic review with meta-analyses that evaluates the effectiveness of the Pilates method on the pain and functionality outcome in adults with non-specific chronic low back pain.
  44. ncbi Effects of Pilates-based exercises on pain and disability in individuals with persistent nonspecific low back pain: a systematic review with meta-analysis
    Edwin Choon Wyn Lim
    Department of Physiotherapy, Singapore General Hospital, Singapore
    J Orthop Sports Phys Ther 41:70-80. 2011
    ..A systematic review with meta-analysis...
  45. ncbi Low back pain symptoms show a similar pattern of improvement following a wide range of primary care treatments: a systematic review of randomized clinical trials
    Majid Artus
    Arthritis Research UK National Primary Care Centre, Primary Care Sciences, Keele University, Keele, Staffordshire ST5 5BG, UK
    Rheumatology (Oxford) 49:2346-56. 2010
    To assess overall responses to treatments among non-specific low back pain (NSLBP) patients in clinical trials to examine the pattern following a wide range of treatments.
  46. ncbi US national prevalence and correlates of low back and neck pain among adults
    Tara W Strine
    Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Arthritis Rheum 57:656-65. 2007
    To estimate the US prevalence and psychological and health behavior correlates of low back pain and/or neck pain...
  47. ncbi Psychosocial risk factors for chronic low back pain in primary care--a systematic review
    Aline Ramond
    Département de médecine générale, Universite d Angers, Angers, France
    Fam Pract 28:12-21. 2011
    b>Low back pain (LBP) is a major public health problem, often encountered in primary care. Guidelines recommend early identification of psychosocial factors that could prevent recovery from acute LBP.
  48. ncbi Treatment-based subgroups of low back pain: a guide to appraisal of research studies and a summary of current evidence
    Steven J Kamper
    The George Institute for International Health, University of Sydney, PO Box M201, Missenden Rd, Camperdown, NSW 2050, Australia
    Best Pract Res Clin Rheumatol 24:181-91. 2010
    There has been a recent increase in research evaluating treatment-based subgroups of non-specific low back pain. The aim of these sub-classification schemes is to identify subgroups of patients who will respond preferentially to one ..
  49. ncbi Causal assessment of occupational lifting and low back pain: results of a systematic review
    Eugene K Wai
    Division of Orthopaedic Surgery, Department of Surgery, University of Ottawa, Ottawa, Ontario, Canada
    Spine J 10:554-66. 2010
    b>Low back pain (LBP) is a disorder that commonly affects the working population, resulting in disability, health-care utilization, and a heavy socioeconomic burden...
  50. pmc Barriers and progress in the treatment of low back pain
    Nadine E Foster
    Keele University, Keele, Staffordshire, UK
    BMC Med 9:108. 2011
    b>Low back pain is a common and costly condition and for most people is likely to be a recurrent problem throughout their lifetime...
  51. pmc Individuals with chronic low back pain have greater difficulty in engaging in positive lifestyle behaviours than those without back pain: an assessment of health literacy
    Andrew M Briggs
    School of Physiotherapy and Curtin Health Innovation Research Institute, Curtin University, Australia
    BMC Musculoskelet Disord 12:161. 2011
    Despite the large volume of research dedicated to understanding chronic low back pain (CLBP), patient outcomes remain modest while healthcare costs continue to rise, creating a major public health burden...
  52. ncbi Pharmacotherapy of low back pain: targeting nociceptive and neuropathic pain components
    Bart Morlion
    University Hospitals Leuven, Leuven, Belgium
    Curr Med Res Opin 27:11-33. 2011
    To review pharmacological management of chronic low back pain (LBP), with respect to management of nociceptive and neuropathic components.
  53. ncbi Back pain prevalence and visit rates: estimates from U.S. national surveys, 2002
    Richard A Deyo
    Department of Medicine, University of Washington, Seattle, WA, USA
    Spine (Phila Pa 1976) 31:2724-7. 2006
    ..Review and analysis of data from two U.S. national surveys in 2002...
  54. ncbi 15. Discogenic low back pain
    Jan Willem Kallewaard
    Department of Anesthesiology and Pain Management, Alysis Rijnstate Hospital, Arnhem, The Netherlands
    Pain Pract 10:560-79. 2010
    ..Various interventional treatment strategies for chronic discogenic low back pain unresponsive to conservative care include reduction of inflammation, ablation of intradiscal nociceptors, ..
  55. pmc The impact of placebo, psychopathology, and expectations on the response to acupuncture needling in patients with chronic low back pain
    Ajay Darsh Wasan
    Department of Anesthesiology, Women s Hospital and Harvard Medical School, Boston, Massachusetts, USA
    J Pain 11:555-63. 2010
    ..a variable not explored in the acupuncture RCTs that could explain whether subgroups of patients with chronic low back pain have differential responses to acupuncture or placebo treatments...
  56. ncbi 2001 Volvo Award Winner in Clinical Studies: Lumbar fusion versus nonsurgical treatment for chronic low back pain: a multicenter randomized controlled trial from the Swedish Lumbar Spine Study Group
    P Fritzell
    Department of Orthopedic Surgery, Falun Hospital, 79182 Falun, Sweden
    Spine (Phila Pa 1976) 26:2521-32; discussion 2532-4. 2001
    ..A randomized controlled multicenter study with a 2-year follow-up by an independent observer...
  57. ncbi The impact of body mass index on the prevalence of low back pain: the HUNT study
    Ingrid Heuch
    Department of Neurology, Oslo University Hospital, Oslo, Norway
    Spine (Phila Pa 1976) 35:764-8. 2010
    ..A cross-sectional population-based study...
  58. ncbi Low back pain in relation to lumbar disc degeneration
    K Luoma
    Finnish Institute of Occupational Health, Helsinki, Finland
    Spine (Phila Pa 1976) 25:487-92. 2000
    ..Cross-sectional magnetic resonance imaging (MRI) study...
  59. ncbi Measuring the global burden of low back pain
    Damian Hoy
    University of Queensland, School of Population Health, Centre for Burden of Disease and Cost Effectiveness, Herston Rd, Herston, QLD 4006, Australia
    Best Pract Res Clin Rheumatol 24:155-65. 2010
    b>Low back pain is a major cause of morbidity in high-, middle- and low-income countries, yet to date it has been relatively under-prioritised and under-funded...
  60. ncbi The clinical importance of changes in outcome scores after treatment for chronic low back pain
    O Hägg
    Department of Orthopaedic Surgery, Sahlgren University Hospital, 413 45 Gothenburg, Sweden
    Eur Spine J 12:12-20. 2003
    When measuring treatment effect in chronic low back pain with multi-item outcome instruments, it is necessary, both for clinical decision-making and research purposes, to understand the clinical importance of the outcome scores...
  61. pmc A modified Delphi approach to standardize low back pain recurrence terminology
    Tasha R Stanton
    The George Institute for Global Health, The University of Sydney, PO Box M201, Missenden Road, Sydney, NSW, 2050, Australia
    Eur Spine J 20:744-52. 2011
    Lack of standardization of terminology in low back pain (LBP) research has significantly impeded progress in this area...
  62. pmc Recruitment difficulties in a primary care cluster randomised trial: investigating factors contributing to general practitioners' recruitment of patients
    Matthew J Page
    School of Public Health and Preventive Medicine, Monash University, Melbourne, Australia
    BMC Med Res Methodol 11:35. 2011
    ....
  63. ncbi Interpreting change scores for pain and functional status in low back pain: towards international consensus regarding minimal important change
    Raymond W J G Ostelo
    EMGO Institute, VU University Medical Centre, Amsterdam, The Netherlands
    Spine (Phila Pa 1976) 33:90-4. 2008
    Literature review, expert panel, and a workshop during the "VIII International Forum on Primary Care Research on Low Back Pain" (Amsterdam, June 2006).
  64. ncbi Lumbar disc disorders and low-back pain: socioeconomic factors and consequences
    Jeffrey N Katz
    Section of Clinical Sciences, Division of Rheumatology, Immunology and Allergy, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    J Bone Joint Surg Am 88:21-4. 2006
    ..These methodologic challenges notwithstanding, the toll of lumbar disc disorders is enormous, underscoring the critical importance of identifying strategies to prevent these disorders and their consequences...
  65. ncbi Group cognitive behavioural treatment for low-back pain in primary care: a randomised controlled trial and cost-effectiveness analysis
    Sarah E Lamb
    Warwick Clinical Trials Unit, Warwick Medical School, University of Warwick, Coventry, UK
    Lancet 375:916-23. 2010
    ..Low-back pain is a common and costly problem. We estimated the effectiveness of a group cognitive behavioural intervention in addition to best practice advice in people with low-back pain in primary care...
  66. ncbi The cost diary: a method to measure direct and indirect costs in cost-effectiveness research
    M E Goossens
    Institute for Rehabilitation Research, Hoensbroek, The Netherlands
    J Clin Epidemiol 53:688-95. 2000
    ..clinical trials evaluating the cost-effectiveness of behavioral rehabilitation in 205 fibromyalgia and chronic low back pain patients...
  67. ncbi The course of low back pain from adolescence to adulthood: eight-year follow-up of 9600 twins
    Lise Hestbaek
    Back Research Center, Backcenter Fynen, Clinical Locomotion Science, University of Southern Denmark, Ringe, Denmark
    Spine (Phila Pa 1976) 31:468-72. 2006
    ..Prospective study with 8-year follow-up...
  68. pmc The impact of chronic low back pain on older adults: a comparative study of patients and controls
    Thomas E Rudy
    Department of Anesthesiology, Pain Evaluation and Treatment Institute and University of Pittsburgh, Pittsburgh, PA 15206, USA
    Pain 131:293-301. 2007
    Chronic low back pain (CLBP) is one of the most common, poorly understood, and potentially disabling chronic pain conditions from which older adults suffer...
  69. ncbi A population-based study of juvenile disc degeneration and its association with overweight and obesity, low back pain, and diminished functional status
    Dino Samartzis
    Department of Orthopaedics and Traumatology, University of Hong Kong, Hong Kong, SAR, China
    J Bone Joint Surg Am 93:662-70. 2011
    ..Consequently, the purpose of this study was to assess the prevalence, determinants, and clinical relevance associated with juvenile disc degeneration of the lumbar spine in individuals without spinal deformities...
  70. pmc Evaluation of lumbar facet joint nerve blocks in managing chronic low back pain: a randomized, double-blind, controlled trial with a 2-year follow-up
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Int J Med Sci 7:124-35. 2010
    ..A randomized, double-blind, controlled trial...
  71. ncbi Model for the work-relatedness of low-back pain
    Freek Lötters
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Scand J Work Environ Health 29:431-40. 2003
    ....
  72. ncbi Health literacy and beliefs among a community cohort with and without chronic low back pain
    Andrew M Briggs
    School of Physiotherapy and Curtin Health Innovation Research Institute, Curtin University of Technology, Australia
    Pain 150:275-83. 2010
    ..with poorer health outcomes in many chronic conditions although this has not been studied in chronic low back pain (CLBP). We examined the health literacy of individuals with CLBP using a mixed methods approach...
  73. ncbi Psychosocial factors predictive of occupational low back disability: towards development of a return-to-work model
    I Z Schultz
    Department of Educational and Counselling Psychology, and Special Education, University of British Columbia, Room 297, 2125 Main Mall, Vancouver, BC, Canada V6T 1Z4
    Pain 107:77-85. 2004
    ..All psychosocial models were better at predicting who will return than who will not return to work...
  74. pmc Overtreating chronic back pain: time to back off?
    Richard A Deyo
    Department of Medicine, Oregon Health and Science University, Portland, OR, USA
    J Am Board Fam Med 22:62-8. 2009
    ....
  75. ncbi Patterns of care for low back pain in a working population
    W IJzelenberg
    Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
    Spine (Phila Pa 1976) 29:1362-8. 2004
    ..A prospective longitudinal study with 1-year follow-up...
  76. pmc Prognosis for patients with chronic low back pain: inception cohort study
    Luciola da C Menezes Costa
    George Institute for International Health, University of Sydney
    BMJ 339:b3829. 2009
    To describe the course of chronic low back pain in an inception cohort and to identify prognostic markers at the onset of chronicity.
  77. ncbi Evaluation of the effectiveness and efficacy of Iyengar yoga therapy on chronic low back pain
    Kimberly Williams
    Department of Community Medicine, West Virginia University, Morgantown, USA
    Spine (Phila Pa 1976) 34:2066-76. 2009
    The effectiveness and efficacy of Iyengar yoga for chronic low back pain (CLBP) were assessed with intention-to-treat and per-protocol analysis...
  78. pmc Mindfulness meditation for the treatment of chronic low back pain in older adults: a randomized controlled pilot study
    Natalia E Morone
    Department of Medicine, Division of General Internal Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    Pain 134:310-9. 2008
    ..adherence to an eight-session mindfulness meditation program for community-dwelling older adults with chronic low back pain (CLBP) and to develop initial estimates of treatment effects...
  79. ncbi Evidence of augmented central pain processing in idiopathic chronic low back pain
    Thorsten Giesecke
    University of Michigan, Ann Arbor, MI 48106, USA
    Arthritis Rheum 50:613-23. 2004
    For many individuals with chronic low back pain (CLBP), there is no identifiable cause...
  80. ncbi What is the prognosis of back pain?
    J A Hayden
    Department of Community Health and Epidemiology, Dalhousie University, Halifax, Nova Scotia, Canada
    Best Pract Res Clin Rheumatol 24:167-79. 2010
    Understanding prognosis is important in managing low back pain. In this article, we discuss the available evidence on low back pain prognosis and describe how prognostic evidence can be used to inform clinical decision making...
  81. ncbi Systematic reviews of low back pain prognosis had variable methods and results: guidance for future prognosis reviews
    J A Hayden
    Centre of Research Expertise in Improved Disability Outcomes CREIDO, University Health Network, Toronto, Ontario, Canada
    J Clin Epidemiol 62:781-796.e1. 2009
    Systematic reviews of prognostic factors for low back pain vary substantially in design and conduct...
  82. pmc Randomised controlled trial of integrated care to reduce disability from chronic low back pain in working and private life
    Ludeke C Lambeek
    Department of Public and Occupational Health, EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, Netherlands
    BMJ 340:c1035. 2010
    To evaluate the effectiveness of an integrated care programme, combining a patient directed and a workplace directed intervention, for patients with chronic low back pain.
  83. ncbi A consensus approach toward the standardization of back pain definitions for use in prevalence studies
    Clermont E Dionne
    Population Health Research Unit, URESP Research Centre of the Laval University Affiliated Hospital, Quebec, QC, Canada
    Spine (Phila Pa 1976) 33:95-103. 2008
    ..A modified Delphi study conducted with 28 experts in back pain research from 12 countries...
  84. ncbi Epidemiology of chronic musculoskeletal pain
    John McBeth
    ARC Epidemiology Unit, The Medical School, The University of Manchester, Manchester, M13 9PT, UK
    Best Pract Res Clin Rheumatol 21:403-25. 2007
    ..and adult populations is examined, with a focus on three commonly reported pain disorders: shoulder pain, low back pain and fibromyalgia/chronic widespread pain...
  85. ncbi Comorbid subjective health complaints in low back pain
    Eli Molde Hagen
    Spine Clinic, Sykehuset Innlandet HF, Ottestad, Norway
    Spine (Phila Pa 1976) 31:1491-5. 2006
    ..Cross-sectional study...
  86. ncbi A comparison of a modified Oswestry Low Back Pain Disability Questionnaire and the Quebec Back Pain Disability Scale
    J M Fritz
    Department of Physical Therapy, School of Allied Health and Rehabilitation Sciences, University of Pittsburgh, 6035 Forbes Tower, Pittsburgh, PA 15260, USA
    Phys Ther 81:776-88. 2001
    ..global rating of change as a reflection of meaningful change in patient status and to compare the measurement properties of a modified Oswestry Low Back Pain Disability Questionnaire (OSW) and the Quebec Back Pain Disability Scale (QUE).
  87. ncbi Risk factors for the development of low back pain in adolescence
    D E Feldman
    Centre for Clinical Epidemiology and Community Studies, SMBD Jewish General Hospital, McGill University, Montreal, Quebec, Canada
    Am J Epidemiol 154:30-6. 2001
    A previous history and earlier onset of low back pain are associated with chronic low back pain in adults, implying that prevention in adolescence may have a positive impact in adulthood...
  88. ncbi Effectiveness of therapeutic lumbar transforaminal epidural steroid injections in managing lumbar spinal pain
    Laxmaiah Manchikanti
    Pain Management Center of Paducah, Paducah, KY, USA
    Pain Physician 15:E199-245. 2012
    ..However, there are only a few well-designed, randomized, controlled studies on the effectiveness of steroid injections. Consequently, multiple systematic reviews with diverse opinions have been published...
  89. pmc Neck/shoulder pain and low back pain among school teachers in China, prevalence and risk factors
    Pengying Yue
    Injury Prevention Research Center, Medical College of Shantou University, 22 Xinling Road, Shantou, 515041, China
    BMC Public Health 12:789. 2012
    ..an occupational group among which there appears to be a high prevalence of neck and/or shoulder pain (NSP) and low back pain (LBP). Epidemiological data on NSP and LBP in Chinese teachers are limited...
  90. pmc Prevalence of low back pain in children and adolescents: a meta-analysis
    Inmaculada Calvo-Muñoz
    Department Physiotherapy, Faculty of Medicine, Espinardo Campus, University of Murcia, Murcia, 30100, Spain
    BMC Pediatr 13:14. 2013
    b>Low back pain (LBP) is common in children and adolescents, and it is becoming a public health concern...
  91. ncbi The association between health care professional attitudes and beliefs and the attitudes and beliefs, clinical management, and outcomes of patients with low back pain: a systematic review
    B Darlow
    Department of Primary Health Care and General Practice, University of Otago, Wellington, PO Box 7343, Wellington South, 6242, New Zealand
    Eur J Pain 16:3-17. 2012
    ..health care professional (HCP) attitudes and beliefs may negatively influence the beliefs of patients with low back pain (LBP), but this has not been systematically reviewed...
  92. ncbi The association between chronic low back pain and sleep: a systematic review
    Gráinne A Kelly
    UCD School of Public Health, Physiotherapy and Population Science, Health Sciences Centre, University College Dublin, Belfield, Dublin, Ireland
    Clin J Pain 27:169-81. 2011
    chronic low back pain (CLBP) adversely affects many quality of life components, and is reported to impair sleep. The aim of this review was to determine the association between CLBP and sleep.
  93. ncbi Impact of psychological factors in the experience of pain
    Steven J Linton
    Center for Health and Medical Psychology CHAMP, School of Law, Psychology and Social Work, Orebro University, Örebro 701 82, Sweden
    Phys Ther 91:700-11. 2011
    ..Because psychological processes have an influence on both the experience of pain and the treatment outcome, the integration of psychological principles into physical therapy treatment would seem to have potential to enhance outcomes...
  94. ncbi Sex differences in presentation, course, and management of low back pain in primary care
    Jean Francois Chenot
    Department of General Practice parallelDepartment of Anesthesiology, Pain Clinic, University Goettingen, Germany
    Clin J Pain 24:578-84. 2008
    Epidemiologic surveys frequently show that women more often and are more affected by low back pain (LBP)...
  95. pmc Chapter 2. European guidelines for prevention in low back pain : November 2004
    A K Burton
    Eur Spine J 15:S136-68. 2006
  96. ncbi Treating non-specific chronic low back pain through the Pilates Method
    Roy La Touche
    Physiotherapy and Human Movement Research Unit, Pilates Core Kinesis, Madrid, Spain
    J Bodyw Mov Ther 12:364-70. 2008
    ..review and analyze scientific articles where the Pilates Method was used as treatment for non-specific chronic low back pain (CLBP). Articles were searched using the Medline, EMBASE, PEDro, CINAHL, and SPORTDICUS databases...
  97. ncbi Yoga for chronic low back pain: a randomized trial
    Helen E Tilbrook
    University of York, Heslington, United Kingdom
    Ann Intern Med 155:569-78. 2011
    Previous studies indicate that yoga may be an effective treatment for chronic or recurrent low back pain.
  98. pmc How do we define the condition 'recurrent low back pain'? A systematic review
    Tasha R Stanton
    The George Institute for International Health, The University of Sydney, Missenden Road, PO Box M201, Sydney NSW, 2050, Australia
    Eur Spine J 19:533-9. 2010
    Recurrent low back pain (recurrent LBP) is a common condition, however, it is unclear if uniform definitions are used in studies investigating the prevalence and management of this condition...
  99. ncbi Imaging strategies for low-back pain: systematic review and meta-analysis
    Roger Chou
    Oregon Health and Science University, Portland, OR, USA
    Lancet 373:463-72. 2009
    ..We investigated the effects of routine, immediate lumbar imaging versus usual clinical care without immediate imaging on clinical outcomes in patients with low-back pain and no indication of serious underlying conditions...
  100. ncbi How often is low back pain not coming from the back?
    Jonathan N Sembrano
    Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, USA
    Spine (Phila Pa 1976) 34:E27-32. 2009
    ..Consecutive case series cohort...
  101. pmc Yoga for chronic low back pain in a predominantly minority population: a pilot randomized controlled trial
    Robert B Saper
    Department of Family Medicine, Boston University School of Medicine and Boston Medical Center, Massachusetts, USA
    Altern Ther Health Med 15:18-27. 2009
    Several studies suggest yoga may be effective for chronic low back pain; however, trials targeting minorities have not been conducted...

Research Grants67

  1. Innovative Tools for In Vivo Computational Prediction of Lumbar Stresses
    RICHARD DAVID KOMISTEK; Fiscal Year: 2010
    ....
  2. Connective tissue and nervous system mechanisms of CAM therapies for low back pai
    Helene M Langevin; Fiscal Year: 2013
    ..g. yoga) CAM therapies that have been found to be efficacious in clinical trials of chronic and recurrent low back pain (LBP)...
  3. Development of a Yoga Intervention for Antenatal Depression
    Cynthia L Battle; Fiscal Year: 2012
    ..If shown to be effective, yoga could provide depressed women with an option for treatment that may be more acceptable than existing treatments. ..
  4. Self-assembling Biomimetic Hydrogels with Bioadhesive Properties for Intervertebr
    ANDREA JENNIFER VERNENGO; Fiscal Year: 2013
    ....
  5. Stem cells from the intervertebral disc: do they vary in degeneration?
    Zulma Gazit; Fiscal Year: 2010
    ..It is our hypothesis that stem cells residing in the degenerated nucleus pulposus demonstrate a change in their number and/or differentiation profile compared to SCs in healthy discs. ..
  6. Regeneration of Nucleus Pulposus by Tissue Engineering
    Irving M Shapiro; Fiscal Year: 2013
    ..The goal of the proposal is to understand the mechanism that controls the fate and function of these progenitor cells in both the normal and diseased intervertebral disc. ..
  7. Development and Validation of Measures of Pain Behaviors in Chronic Pain
    KARON FRANCES COOK; Fiscal Year: 2010
    ..Chronic pain complaints include headache, low back pain, cancer pain, arthritis pain, neurogenic pain (pain resulting from damage to the peripheral nerves or to the ..
  8. Biological and clinical outcomes of chiropractic spinal manipulative therapy in t
    PAUL BURTON BISHOP; Fiscal Year: 2013
    ..This information will also help to inform the design f other future studies on the putative biological mechanisms of HVLA-SMT, particularly in the treatment of patients with acute sciatica from lumbar disc herniation. ..
  9. A Cognitive Behavioral Chronic Pain Workbook
    Kelly M Carpenter; Fiscal Year: 2010
    Between 10 and 28 percent of Americans suffer from chronic low back pain (CLBP)...
  10. An injectable biocompatible hydrogel nucleus pulposus replacement
    Gavin Braithwaite; Fiscal Year: 2009
    ....
  11. Comparative Efficacy of Treatments for Lumbar Spine
    Daniel Resnick; Fiscal Year: 2009
    DESCRIPTION (PROVIDED BY APPLICANT): Low back pain and associated disorders are a major social, political, economic, and medical problem in the United States...
  12. Spinal Control during Functional Activities to Improve Low Back Pain Outcomes
    LINDA R VANDILLEN; Fiscal Year: 2013
    ..provided by applicant): Our overall objective is to improve the costly long-term course of mechanical low back pain (LBP)...
  13. Recurrent Low Back Pain: Linking Mechanisms to Outcomes
    Sheri P Silfies; Fiscal Year: 2010
    ..investigation of the mechanism underlying poor trunk motor control in individuals with recurrent or chronic low back pain (LBP)...
  14. Virtual Relaxation Environment for Chronic Back Pain
    Libby Tannenbaum; Fiscal Year: 2004
    ..The long term objective is to test a comprehensive, computerbased, cognitive-behavioral treatment package for CLBP. Potential exists to extend such a package to address a broad range of psychological and health issues. ..
  15. CHRONIC LOW BACK PAIN AS A MODEL OF FIBROMYALGIA
    Daniel Clauw; Fiscal Year: 2002
    ..abstract_text> ..
  16. Injectable Delivery of Bone Growth Factor, HomoSer3-AIII
    Richard Berg; Fiscal Year: 2005
    ..If this project and future phase II SBIR development studies leads to a cost-effective formulation for bone healing, FzioMed will manufacture, market and distribute this product to orthopedic surgeons. ..
  17. CHRONIC PROSTATITIS COLLABORATIVE CLINICAL RESEARCH STUD
    Mark Litwin; Fiscal Year: 1999
    ....
  18. Physiological Indicators of Perceived Suffering in a Loved One' Spousal Reactions
    JOAN E MONIN; Fiscal Year: 2010
    ....
  19. A Pilot Trial of IV Pamidronate for Low Back Pain
    Marco Pappagallo; Fiscal Year: 2005
    ..abstract_text> ..
  20. Development of CB2 Agonists for Treatment of Pain
    ANURADHA MAHADEVAN; Fiscal Year: 2010
    ..The long-term goal of this proposal is to develop a medication for the treatment of chronic pain conditions without undesirable CNS side effects. ..
  21. AN AMBULATORY LORDOSIMETER FOR POSTURE CONTROL
    Patrick Hamilton; Fiscal Year: 2007
    ..Using our device, patients will learn to maintain improved lumbar curvature while sitting, and we will investigate whether this improved posture reduces the severity and/or duration of lower back pain. [unreadable] [unreadable]..
  22. Functional Impact of PENS for 65+ Chronic Low Back Pain
    Debra Weiner; Fiscal Year: 2006
    Chronic low back pain (CLBP) plagues greater than 6 million community dwelling older adults, and causes physical and psychosocial dysfunction as well as increased utilization of health care resources...
  23. Osteopuncture for OA-Associated Knee Pain & Disability
    Debra Weiner; Fiscal Year: 2005
    ..In addition, mechanisms of action will be explored, and the impact of osteopuncture on health care costs determined. ..
  24. Behavioral Interventions for Low Back Pain
    STEVEN GEORGE; Fiscal Year: 2007
    ..The dominant role that psychosocial factors play in the development of chronic disability from low back pain has been well established in the literature...
  25. AN EVALUATION AND TREATMENT STUDY OF TMD
    Robert Gatchel; Fiscal Year: 2004
    ..The better understanding of such a mechanism can potentially yield even more effective assessment and treatment approaches for chronic pain syndromes such as TMD. ..
  26. BIOMECHANICAL/PSYCHOSOCIAL RISKS FOR LOW BACK DISORDERS
    William Marras; Fiscal Year: 2003
    ..We will also be able to discern when and under what conditions an intervention to improve the psycho social work environment will be likely to reduce LBP and its associated morbidity. ..
  27. Neuro-Fuzzy Prediction of Spine Loads in Response to Ri*
    William Marras; Fiscal Year: 2005
    ..First, it can be used to assess the risk of spine structure damage believed to contribute to low back pain as a function of work dimensions commonly associated with the workplace...
  28. MUSCLE OVEREXERTION DURING REPETITIVE LIFTING
    William Marras; Fiscal Year: 2003
    ..These results will provide quantitative guidance for the mediation of work-related LBDs for the millions of workers performing materials handling tasks in manufacturing and distribution center environments. ..
  29. EARLY DETECTION AND PREVENTION OF CHRONIC PAIN DISABILIT
    Robert Gatchel; Fiscal Year: 2003
    ..research projects that evaluate an early prediction-intervention approach to 2 costly chronic pain syndromes-low back pain (LBP) and temporomandibular disorder (TMD)...
  30. Comorbidity of Mental Disorders and Pain
    Robert Gatchel; Fiscal Year: 2008
    ..This Award will enable me to maintain the momentum and clinical research advances of two previous consecutive K02 awards from NIMH. ..
  31. PREVENTING CO-MORBID MENTAL & PHYSICAL HEALTH DISABILITY
    Robert Gatchel; Fiscal Year: 2007
    ..model of early intervention in order to maximize the prevention of chronicity in high-risk acute low back pain patients...
  32. LOW BACK PAIN: A MOTOR CONTROL IMPAIRMENT?
    Sharon Henry; Fiscal Year: 2002
    ..work covers the rehabilitation of persons with neurological and musculoskeletal impairments particularly low back pain (LBP)...
  33. Predicting Recurrence of Low Back Pain - Study #2
    James Thomas; Fiscal Year: 2007
    ..how physical and psychological factors interact in the recovery process following an initial episode of low back pain and to determine how these factors contribute to risk for recurrence...
  34. Mechanisms of specific trunk Exercises in low back pain
    Sharon M Henry; Fiscal Year: 2010
    ..3 Low back pain (LBP) is a musculoskeletal condition that affects up to 80% of all people at some point in their lifetime, ..
  35. Relaxation-related CAM Therapies for Chronic Back Pain
    Daniel Cherkin; Fiscal Year: 2002
    ..massage, tai chi, and meditation) that are appropriate for both older and younger adults with chronic low back pain. During Phase I, we will develop, test and refine specific components of a randomized clinical trial ..
  36. PAIN REGULATORY SYSTEM DYSFUNCTION IN CHRONIC PAIN
    Stephen Bruehl; Fiscal Year: 2002
    ..Greater pain duration is expected to be associated with smaller changes in the BP/pain relationship in response to opioid blockade. ..
  37. Repressive Style, suppression and chronic Pain
    John Burns; Fiscal Year: 2004
    ..Moreover, findings should provide theoretical principles on which to found new intervention strategies (e.g., "regulating" suppression by engaging in cognitive exercises). ..
  38. EVALUATING THE EFFICACY OF ACUPUNCTURE FOR BACK PAIN
    Daniel Cherkin; Fiscal Year: 2001
    ..information to design and pilot test a randomized clinical trial of the efficacy of acupuncture for persistent low back pain. We will first develop the methods necessary for a valid and meaningful evaluation of acupuncture...
  39. ANGER, SYMPTOM SPECIFIC REACTIVITY AND CHRONIC PAIN
    John Burns; Fiscal Year: 2002
    ..A "symptom-specificity model" is advanced in which chronic low back pain (CLBP) patients can be distinguished from patients with chronic nonback pain and from normals on the basis of ..
  40. Efficacy of Acupuncture for Chronic Low Back Pain
    Daniel Cherkin; Fiscal Year: 2007
    ..trial is proposed to clarify the extent to which acupuncture needling can diminish the effect of chronic low back pain on patient functioning and symptoms...
  41. Anger Expression, Opioid Dysfunction, and Chronic Pain
    Stephen Bruehl; Fiscal Year: 2009
    ..One hundred forty subjects with chronic low back pain and 80 pain-free healthy subjects will participate in two laboratory sessions, once under opioid blockade with ..
  42. Z Joint Changes in Low Back Pain Following Adjusting
    Gregory Cramer; Fiscal Year: 2009
    ..Z) joints following side-posture positioning and side-posture spinal adjusting in subjects with acute low back pain (LBP)...
  43. Effect of Massage on Chronic Low Back Pain
    Daniel Cherkin; Fiscal Year: 2008
    ..The primary aim of this study is to determine if relaxation massage is an effective treatment for chronic low back pain. If found effective, relaxation massage would represent a widely available and safe alternative to commonly ..
  44. Pain Regulatory Dysfunction in Chronic Pain
    Stephen Bruehl; Fiscal Year: 2007
    ..Sixty chronic low back pain patients and 60 pain-free controls will participate in two laboratory sessions, once under alpha-2 adrenergic ..
  45. Anger Expression, Endogenous Opioids and Acute Pain
    John Burns; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  46. Academic Career Developmet Award in CAM
    RALPH GAY; Fiscal Year: 2006
    ..research competencies to complete a feasibility study of Flexion- Distraction manipulation treatment of low back pain, 3) Acquisition of grant writing and submission of grant applications for future studies in manual medicine, 4)..
  47. MECHANICALLY-BASED IMPAIRMENT MEASURES OF LOW BACK PAIN
    Linda Van Dillen; Fiscal Year: 2004
    ..Studies have been designed to test the general hypothesis that mechanical low back pain (MLBP) results, in part, from a tendency of the lumbar spine to favor movement in a specific direction when ..
  48. Soft Tissue Biomechanical Behavior During Acupuncture in Low Back Pain
    Helene M Langevin; Fiscal Year: 2010
    The goal of this proposal is to test the overall hypothesis that subjects with chronic or recurrent low back pain (LBP) have an abnormal soft tissue response to acupuncture needling, and that this altered response is associated with ..
  49. BIOMECHANICAL EFFECT OF ACUPUNCTURE NEEDLING
    HELENE LANGEVIN; Fiscal Year: 2001
    ..This will contribute to the fundamental understanding of acupuncture therapy and may lead to improvements in treatments. ..
  50. Mechanisms of Neural Mobilization for Chronic Pain
    STEVEN GEORGE; Fiscal Year: 2007
    ..These data may also provide support for a future clinical trial investigating the efficacy of median nerve NMT for patients with CTS. [unreadable] [unreadable] [unreadable]..
  51. Back pain Outcomes using Longitudinal Data (BOLD)
    Jeffrey G Jarvik; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Low back pain is one of the most important causes of functional limitation and disability, an Institute of Medicine priority condition, and it remains a particularly important problem for the elderly,..
  52. CLINICAL INVESTIGATOR TRAINING ENHANCEMENT: CITE PROGRAM
    Kurt Kroenke; Fiscal Year: 2004
    ..abstract_text> ..
  53. Neurohormonal Effects of Massage Therapy
    Tiffany Field; Fiscal Year: 2007
    ..The K05 would allow me to increase my research time including being mentored and mentoring students from 25 to 75% time. [unreadable] [unreadable] [unreadable]..
  54. Enhancing the Placebo Effect in Irritable Bowel Syndrome
    Ted Kaptchuk; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  55. Structure-Function of the Glenohumeral Joint
    Richard Hughes; Fiscal Year: 2006
    ..The project will be a multi-institutional collaboration, although the majority of the work will be performed at the Orthopaedic Research Laboratories of the University of Michigan. [unreadable] [unreadable]..
  56. An Integrative Healing Model in IBS
    Ted Kaptchuk; Fiscal Year: 2005
    ..abstract_text> ..
  57. CANCER PREVENTION PROGRAM IN RURAL CHURCHES
    Richard Winett; Fiscal Year: 2003
    ..Measures of SCT determinants will address the theoretical underpinnings of the intervention, and process measures will assess fidelity, dose, and contamination issues. ..
  58. Progressive scoliosis deformity in intervertebral disc
    Ian Stokes; Fiscal Year: 2009
    ..These approaches may include improvements in brace design, new possibilities for muscle rehabilitation, and surgical procedures aimed at early, minimally invasive modification of spinal growth. ..
  59. MECHANISM OF PAIN IN PATIENTS WITH FIBROMYALGIA SYNDROME
    Roland Staud; Fiscal Year: 2008
    ..In addition, our findings may contribute to the understanding of pain mechanisms related to other chronic pain disorders. ..
  60. Technology Enhanced Depression Intervention (TEDI)
    KELLY CARPENTER; Fiscal Year: 2002
    ..abstract_text> ..
  61. MECHANICAL MODULATION OF GROWTH IN PHYSES
    Ian Stokes; Fiscal Year: 2003
    ..abstract_text> ..
  62. Epidemiology of Depression and Heart Failure in Aging
    Mary Whooley; Fiscal Year: 2009
    ..By identifying the mechanisms that explain the relation between depression and CHF, this study will enable us to target specific areas for improving the treatment of these patients. ..
  63. Paraspinal Denervation in Low Back Pain
    Andrew J Haig; Fiscal Year: 2010
    ..The results will help doctors avoid unnecessary surgery and help scientists to understand more about how spinal stenosis disables so many older people. ..
  64. PARASPINAL MUSCLE DENERVATION AND SYMPTOMS IN LUMBAR SS
    Andrew Haig; Fiscal Year: 2005
    ..Five groups of 30 subjects older than 55 years old, including: asymptomatic persons (healthy persons without low back pain) from the community, persons with lock back pain (LBP) but no stenosis on MRI, persons with stenosis symptoms ..
  65. Stepped Care for Depression and Musculoskeletal Pain
    Kurt Kroenke; Fiscal Year: 2007
    ..Longitudinal assessment of the nondepressed cohort will establish the frequency and risk factors for incident depression. ..
  66. Acupuncture and Low Back Pain during Pregnancy
    Shu Ming Wang; Fiscal Year: 2007
    b>Low back pain (LBP) is a significant clinical problem that is reported to occur in 60% to 90% of individuals. Interestingly, most women experience their first episode of low back pain during pregnancy...