neurologic gait disorders

Summary

Summary: Gait abnormalities that are a manifestation of nervous system dysfunction. These conditions may be caused by a wide variety of disorders which affect motor control, sensory feedback, and muscle strength including: CENTRAL NERVOUS SYSTEM DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or MUSCULAR DISEASES.

Top Publications

  1. ncbi Step training with body weight support: effect of treadmill speed and practice paradigms on poststroke locomotor recovery
    Katherine J Sullivan
    Department of Neurology, University of California, Los Angeles, CA 90095, USA
    Arch Phys Med Rehabil 83:683-91. 2002
  2. ncbi Effect of increases in plantarflexor and hip flexor muscle strength on the levels of effort during gait in individuals with hemiparesis
    Marie Hélène Milot
    Faculte de Medecine, Ecole de readaptation, Université de Montréal and Centre de recherche interdisciplinaire en réadaptation CRIR, Institut de Réadaptation de Montréal, C P 6128, Succursale Centre Ville, Montreal, Que, Canada H3C 3J7
    Clin Biomech (Bristol, Avon) 23:415-23. 2008
  3. ncbi An accelerometry-based comparison of 2 robotic assistive devices for treadmill training of gait
    Jean Philippe Regnaux
    Department of Adult Neurologic Rehabilitation, Hopital Raymond Poincare, Garches, France
    Neurorehabil Neural Repair 22:348-54. 2008
  4. ncbi Understanding ageing effects by approximate entropy analysis of gait variability
    Chandan K Karmakar
    Department of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, Vic, Australia
    Conf Proc IEEE Eng Med Biol Soc 2007:1965-8. 2007
  5. ncbi The control of upright stance in young, elderly and persons with Parkinson's disease
    Nicolas Termoz
    Andre Barbeau Movement Disorders Unit, Hôtel Dieu CHUM, Montreal, Quebec, Canada
    Gait Posture 27:463-70. 2008
  6. ncbi Prospective, blinded, randomized crossover study of gait rehabilitation in stroke patients using the Lokomat gait orthosis
    Andreas Mayr
    Department of Neurology, Hospital Hochzirl, Zirl, Austria
    Neurorehabil Neural Repair 21:307-14. 2007
  7. ncbi Dual-tasking effects on gait variability: the role of aging, falls, and executive function
    Shmuel Springer
    Movement Disorders Unit, Neurology Department, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Mov Disord 21:950-7. 2006
  8. pmc Cueing training in the home improves gait-related mobility in Parkinson's disease: the RESCUE trial
    A Nieuwboer
    Department of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit, Leuven, Belgium
    J Neurol Neurosurg Psychiatry 78:134-40. 2007
  9. ncbi Freezing of gait in patients with advanced Parkinson's disease
    N Giladi
    Department of Neurology, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Israel
    J Neural Transm 108:53-61. 2001
  10. ncbi Impaired regulation of stride variability in Parkinson's disease subjects with freezing of gait
    J M Hausdorff
    Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, 6 Weizmann Street, 64239 Tel Aviv, Israel
    Exp Brain Res 149:187-94. 2003

Research Grants

Detail Information

Publications208 found, 100 shown here

  1. ncbi Step training with body weight support: effect of treadmill speed and practice paradigms on poststroke locomotor recovery
    Katherine J Sullivan
    Department of Neurology, University of California, Los Angeles, CA 90095, USA
    Arch Phys Med Rehabil 83:683-91. 2002
    ..To investigate the effect of practice paradigms that varied treadmill speed during step training with body weight support in subjects with chronic hemiparesis after stroke...
  2. ncbi Effect of increases in plantarflexor and hip flexor muscle strength on the levels of effort during gait in individuals with hemiparesis
    Marie Hélène Milot
    Faculte de Medecine, Ecole de readaptation, Université de Montréal and Centre de recherche interdisciplinaire en réadaptation CRIR, Institut de Réadaptation de Montréal, C P 6128, Succursale Centre Ville, Montreal, Que, Canada H3C 3J7
    Clin Biomech (Bristol, Avon) 23:415-23. 2008
    ..The aim of this study was to assess the effect of strength gain of the affected plantarflexors and hip flexors on bilateral levels of effort during gait, in the sagittal plane of movement...
  3. ncbi An accelerometry-based comparison of 2 robotic assistive devices for treadmill training of gait
    Jean Philippe Regnaux
    Department of Adult Neurologic Rehabilitation, Hopital Raymond Poincare, Garches, France
    Neurorehabil Neural Repair 22:348-54. 2008
    ..Two commercial robotic devices, the Gait Trainer (GT) and the Lokomat (LOKO), assist task-oriented practice of walking. The gait patterns induced by these motor-driven devices have not been characterized and compared...
  4. ncbi Understanding ageing effects by approximate entropy analysis of gait variability
    Chandan K Karmakar
    Department of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, Vic, Australia
    Conf Proc IEEE Eng Med Biol Soc 2007:1965-8. 2007
    ..These findings have implications of understanding ageing effect on gait variability and the likely risks of tripping falls during gait. Results are also potentially useful for the early diagnosis of common gait pathologies...
  5. ncbi The control of upright stance in young, elderly and persons with Parkinson's disease
    Nicolas Termoz
    Andre Barbeau Movement Disorders Unit, Hôtel Dieu CHUM, Montreal, Quebec, Canada
    Gait Posture 27:463-70. 2008
    ..These findings suggest that PD subjects resort to a stiffening strategy to control their balance in postural tasks that imply a mixed control (ankle and hip mechanisms) but have adapted to their stooped posture...
  6. ncbi Prospective, blinded, randomized crossover study of gait rehabilitation in stroke patients using the Lokomat gait orthosis
    Andreas Mayr
    Department of Neurology, Hospital Hochzirl, Zirl, Austria
    Neurorehabil Neural Repair 21:307-14. 2007
    ..This prospective, blinded, randomized controlled study of gait retraining tested the feasibility and potential efficacy of using an electromechanical-driven gait orthosis (Lokomat) for treadmill training...
  7. ncbi Dual-tasking effects on gait variability: the role of aging, falls, and executive function
    Shmuel Springer
    Movement Disorders Unit, Neurology Department, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Mov Disord 21:950-7. 2006
    ..In contrast, dual tasking destabilizes the gait of idiopathic elderly fallers, an effect that appears to be mediated in part by a decline in EF...
  8. pmc Cueing training in the home improves gait-related mobility in Parkinson's disease: the RESCUE trial
    A Nieuwboer
    Department of Rehabilitation Sciences, Faculty of Kinesiology and Rehabilitation Sciences, Katholieke Universiteit, Leuven, Belgium
    J Neurol Neurosurg Psychiatry 78:134-40. 2007
    ..The Rehabilitation in Parkinson's Disease: Strategies for Cueing (RESCUE) trial investigated the effects of a home physiotherapy programme based on rhythmical cueing on gait and gait-related activity...
  9. ncbi Freezing of gait in patients with advanced Parkinson's disease
    N Giladi
    Department of Neurology, Tel-Aviv Medical Center, Sackler Faculty of Medicine, Tel-Aviv University, Israel
    J Neural Transm 108:53-61. 2001
    ..002), early morning foot dystonia (p < 0.003) and significant postural instability (p < 0.0005). CONCLUSION: FOG is a common symptom in advanced PD. It is mainly related to disease progression and levodopa treatment...
  10. ncbi Impaired regulation of stride variability in Parkinson's disease subjects with freezing of gait
    J M Hausdorff
    Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, 6 Weizmann Street, 64239 Tel Aviv, Israel
    Exp Brain Res 149:187-94. 2003
    ....
  11. ncbi Improvements in speed-based gait classifications are meaningful
    Arlene Schmid
    Department of Occupational Therapy, Indiana University School of Health and Rehabilitation Sciences, and the Richard L Roudebush VA Medical Center, Indianapolis, IN 46202 5119, USA
    Stroke 38:2096-100. 2007
    ..8 m/s). The purpose of the current study was to determine whether changes in velocity-based community ambulation classification were related to clinically meaningful changes in stroke-related function and quality of life...
  12. ncbi The power of cueing to circumvent dopamine deficits: a review of physical therapy treatment of gait disturbances in Parkinson's disease
    Tamar C Rubinstein
    Movement Disorders Unit, Neurology Department, Tel Aviv Sourasky Medical Center, and Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Mov Disord 17:1148-60. 2002
    ....
  13. ncbi Treadmill training with partial body weight support and an electromechanical gait trainer for restoration of gait in subacute stroke patients: a randomized crossover study
    C Werner
    Klinik Berlin, Department of Neurological Rehabilitation, Free University Berlin, Greifswald, Germany
    Stroke 33:2895-901. 2002
    ..The gait trainer was designed to provide nonambulatory subjects the repetitive practice of a gait-like movement without overexerting therapists...
  14. ncbi Patient-cooperative strategies for robot-aided treadmill training: first experimental results
    Robert Riener
    Rehabilitation Engineering Group, Automatic Control Laboratory, Swiss Federal Institute of Technology ETH, CH 8092 Zurich, Switzerland
    IEEE Trans Neural Syst Rehabil Eng 13:380-94. 2005
    ..Further improvements of the technical design and additional clinical testing is required to prove whether the therapeutic outcome can be enhanced by such cooperative strategies...
  15. ncbi Postural balance in children with cerebral palsy
    Jessica Rose
    Motion and Gait Analysis Laboratory, Lucile Packard Children s Hospital, Palo Alto, CA 94304, USA
    Dev Med Child Neurol 44:58-63. 2002
    ..Identification of those children with impaired standing balance can delineate factors that contribute to the patient's gait disorder and help to guide treatment...
  16. ncbi Analysis of impairments influencing gait velocity and asymmetry of hemiplegic patients after mild to moderate stroke
    An Lun Hsu
    Department of Physical Therapy, Mackay Memorial Hospital, Taipei, Taiwan, ROC
    Arch Phys Med Rehabil 84:1185-93. 2003
    ..To identify the most important impairments determining gait velocity and asymmetry in patients with mild to moderate stroke...
  17. ncbi Transcutaneous electrical nerve stimulation combined with task-related training improves lower limb functions in subjects with chronic stroke
    Shamay S M Ng
    Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong, China
    Stroke 38:2953-9. 2007
    ....
  18. pmc Development of a universal measure of quadrupedal forelimb-hindlimb coordination using digital motion capture and computerised analysis
    Lindsay Hamilton
    Brain Repair Centre and Department of Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge, CB3 0ES, UK
    BMC Neurosci 8:77. 2007
    ..To achieve this potential a robust method of functional analysis is required so that statistical comparison of numerical data derived from treated and control animals can be achieved...
  19. ncbi Muscles that influence knee flexion velocity in double support: implications for stiff-knee gait
    Saryn R Goldberg
    Department of Mechanical Engineering, Biomechanical Engineering Division, Stanford University, Clark Center, S 342, 318 Campus Drive, Stanford, CA 94305 5450, USA
    J Biomech 37:1189-96. 2004
    ....
  20. pmc Pilot study of Lokomat versus manual-assisted treadmill training for locomotor recovery post-stroke
    Kelly P Westlake
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, USA
    J Neuroeng Rehabil 6:18. 2009
    ....
  21. ncbi Gait retraining post stroke
    Robert W Teasell
    Department of Physical Medicine and Rehabilitation, St Joseph s Health Care London and University of Western Ontario, London, Ontario, Canada
    Top Stroke Rehabil 10:34-65. 2003
    ....
  22. doi Robot assisted gait training with active leg exoskeleton (ALEX)
    Sai K Banala
    Department of Mechanical Engineering, University of Delaware, Newark, DE 19716, USA
    IEEE Trans Neural Syst Rehabil Eng 17:2-8. 2009
    ..Improvement is seen as an increase in the size of the patients' gait pattern, increased knee and ankle joint excursions and increase in their walking speeds on the treadmill...
  23. doi Effects of training with a robot-virtual reality system compared with a robot alone on the gait of individuals after stroke
    Anat Mirelman
    Gait and Neurodynamics Lab, Tel Aviv Medical Center, 6 Weizmann St, Tel Aviv, Israel
    Stroke 40:169-74. 2009
    ..The purpose of this study was to determine whether the transfer of training of LE movements to locomotion was greater using a virtual environment coupled with a robot or with the robot alone...
  24. pmc Biofeedback for robotic gait rehabilitation
    Lars Lunenburger
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    J Neuroeng Rehabil 4:1. 2007
    ..The aim of this study was to define a biofeedback system for a gait training robot and test its usability in subjects without neurological disorders...
  25. ncbi Behavioral and histological characterization of unilateral cervical spinal cord contusion injury in rats
    John C Gensel
    STAR Laboratories, Laboratory for Neural Repair, Department of Neuroscience, The Ohio State University, Columbus, Ohio 43210, USA
    J Neurotrauma 23:36-54. 2006
    ....
  26. ncbi Changes in gait while backward counting in demented older adults with frontal lobe dysfunction
    Gilles Allali
    Department of Rehabilitation and Geriatrics, Geneva University Hospitals, Geneva, Switzerland
    Gait Posture 26:572-6. 2007
    ..A better understanding of dual-task related changes in demented subjects with frontal lobe dysfunction could help us to clarify the role of the frontal lobe in motor gait control...
  27. doi Rehabilitation treatment of gait in patients with Parkinson's disease with freezing: a comparison between two physical therapy protocols using visual and auditory cues with or without treadmill training
    Giuseppe Frazzitta
    Department of Physical Therapy, Scientific Institute of Montescano, S Maugeri Foundation IRCCS, Montescano, Italy
    Mov Disord 24:1139-43. 2009
    ..Our results suggest that treadmill training associated with auditory and visual cues might give better results than more conventional treatments. Treadmill training probably acts as a supplementary external cue...
  28. ncbi Adaptive control of a variable-impedance ankle-foot orthosis to assist drop-foot gait
    Joaquin A Blaya
    Artificial Intelligence Laboratory, Harvard MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA 02139, USA
    IEEE Trans Neural Syst Rehabil Eng 12:24-31. 2004
    ..These results indicate that a variable-impedance orthosis may have certain clinical benefits for the treatment of drop-foot gait compared to conventional ankle-foot orthoses having zero or constant stiffness joint behaviors...
  29. ncbi Effects of external rhythmical cueing on gait in patients with Parkinson's disease: a systematic review
    I Lim
    Department of Physiotherapy, VU University Medical Center, De Boelelaan 1117, P O Box 7057, 1007 MB Amsterdam, The Netherlands
    Clin Rehabil 19:695-713. 2005
    ..To critically review studies evaluating the effects of external rhythmical cueing on gait in patients with Parkinson's disease...
  30. ncbi Treadmill exercise rehabilitation improves ambulatory function and cardiovascular fitness in patients with chronic stroke: a randomized, controlled trial
    Richard F Macko
    Veterans Affairs Medical Center Geriatrics Research, Education, and Clinical Center, Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA
    Stroke 36:2206-11. 2005
    ..We investigated whether treadmill aerobic training (T-AEX) is more effective than conventional rehabilitation to improve ambulatory function and cardiovascular fitness in patients with chronic stroke...
  31. ncbi Vascular calcification and osteolysis in diabetic neuropathy-is RANK-L the missing link?
    W Jeffcoate
    Foot Ulcer Trials Unit, Department of Diabetes and Endocrinology, City Hospital, NG5 1PB, Nottingham, UK
    Diabetologia 47:1488-92. 2004
    ..g. calcitonin gene-related peptide, which normally exert a moderating influence on the pathway...
  32. doi Enhanced gait-related improvements after therapist- versus robotic-assisted locomotor training in subjects with chronic stroke: a randomized controlled study
    T George Hornby
    Department of Physical Therapy, University of Illinois at Chicago, 1919 W Taylor St, M C 898, Chicago, IL 60612, USA
    Stroke 39:1786-92. 2008
    ..Robotic devices that provide consistent symmetrical assistance have been developed to facilitate LT, although their effectiveness in improving locomotor ability has not been well established...
  33. ncbi Gait dynamics in Parkinson's disease: relationship to Parkinsonian features, falls and response to levodopa
    Joanna D Schaafsma
    Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, and Sackler School of Medicine, Tel Aviv University, 6 Weizmann Street, Tel Aviv 64239, Israel
    J Neurol Sci 212:47-53. 2003
    ....
  34. doi Validation of the freezing of gait questionnaire in patients with Parkinson's disease
    Nir Giladi
    Movement Disorders Unit, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
    Mov Disord 24:655-61. 2009
    ..1% using UPDRS item 14 (> or =1) (P < 0.001). FOG-Q was a reliable tool for the assessment of treatment intervention. FOG-Q item 3 was effective as a screening question for the presence of FOG...
  35. doi Gait freezing in Parkinson's disease and the stride length sequence effect interaction
    Rachel Chee
    School of Psychology, Psychiatry and Psychological Medicine, Monash University, Clayton, Victoria, Australia
    Brain 132:2151-60. 2009
    ..These findings support the possible dual requirement of a reduced step length and a successive step to step amplitude reduction to lead to FOG...
  36. ncbi [Analysis of gait disorders in Parkinson's disease assessed with an accelerometer]
    J M Paquet
    Service de Neurologie, Hôpital de Laval
    Rev Neurol (Paris) 159:786-9. 2003
    ..59 (p<0.01); r=-0.65 (p<0.003), respectively)). In conclusion regularity and cranio-caudal activity appeared as the most interesting variables to characterize stabilized Parkinson's gait...
  37. pmc Rotating treadmill training reduces freezing in Parkinson disease: preliminary observations
    Minna Hong
    Program in Physical Therapy, Washington University School of Medicine, St Louis, MO, USA
    Parkinsonism Relat Disord 14:359-63. 2008
    ..Following training: (1) neither subject froze during leftward turns, (2) muscle activity normalized, and (3) turning times decreased for leftward turns...
  38. ncbi Kinematic and kinetic factors that correlate with improved knee flexion following treatment for stiff-knee gait
    Saryn R Goldberg
    Biomechanical Engineering Division, Mechanical Engineering Department, Stanford University, Stanford, CA, USA
    J Biomech 39:689-98. 2006
    ..Therefore, while stiff-knee gait manifests during the swing phase of the gait cycle, it may be caused by abnormal muscle activity during stance...
  39. doi Bilateral coordination of walking and freezing of gait in Parkinson's disease
    Meir Plotnik
    Movement Disorders Unit, Laboratory for Gait and Neurodynamics, Department of Neurology, Tel Aviv Sourasky Medical Center, Israel
    Eur J Neurosci 27:1999-2006. 2008
    ..Poor bilateral coordination of walking may predispose to FOG, especially during challenging tasks that demand a high degree of left-right coordination...
  40. ncbi The CatWalk gait analysis in assessment of both dynamic and static gait changes after adult rat sciatic nerve resection
    Ronald Deumens
    Department of Anesthesiology, Maastricht University, Maastricht, The Netherlands
    J Neurosci Methods 164:120-30. 2007
    ....
  41. pmc Effect of treadmill exercise training on spatial and temporal gait parameters in subjects with chronic stroke: a preliminary report
    Shawnna L Patterson
    Baltimore Department of Veterans Affairs VAMC Medical Center Geriatric Research, Education, and Clinical Center, Baltimore, MD, USA
    J Rehabil Res Dev 45:221-8. 2008
    ..Interlimb symmetry did not change. This study presents preliminary evidence that changes in spatial and temporal gait parameters contribute to the increased velocity of subjects with stroke after T-EX...
  42. ncbi Plasticity of the spinal neural circuitry after injury
    V Reggie Edgerton
    Brain Research Institute, University of California, Los Angeles, California 90095, USA
    Annu Rev Neurosci 27:145-67. 2004
    ..Rehabilitative efforts combining locomotor training pharmacological means and/or spinal cord electrical stimulation paradigms will most likely result in more effective methods of recovery than using only one intervention...
  43. ncbi Posterior tibial tendon transfer: results of fixation to the dorsiflexors proximal to the ankle joint
    Frank Christiaan B M Wagenaar
    Department of Orthopaedic Surgery, Sint Maartenskliniek, Nijmegen, The Netherlands
    Foot Ankle Int 28:1128-42. 2007
    ..The present study is the first to describe the results of posterior tibial tendon transfer through the interosseous membrane attaching only the posterior tibial tendon to the extensor tendons proximal to the ankle joint...
  44. ncbi High frequency stimulation of the subthalamic nucleus improves speed of locomotion but impairs forelimb movement in Parkinsonian rats
    R Vlamings
    Department of Neuroscience, Faculty of Health, Medicine and Life Sciences, Maastricht University, Maastricht, The Netherlands
    Neuroscience 148:815-23. 2007
    ..The static features of gait were only significantly influenced with low amplitude. Remarkably, STN stimulation affected predominantly the forepaws/limbs...
  45. pmc Cerebellar hypoplasia and quadrupedal locomotion in humans as a recessive trait mapping to chromosome 17p
    S Turkmen
    J Med Genet 43:461-4. 2006
    ..In severe cases, patients are unable to ambulate independently, but nevertheless do use bipedal locomotion...
  46. doi Effects of loading the unaffected limb for one session of locomotor training on laboratory measures of gait in stroke
    J P Regnaux
    Laboratoire d analyse du Mouvement, Hôpital R Poincaré 92380 Garches, APHP, UVSQ INSERM U731, UPMC Paris6, France
    Clin Biomech (Bristol, Avon) 23:762-8. 2008
    ..We investigated changes in the walking movements of each lower extremity after weighting the unaffected leg...
  47. pmc New tendon transfer for correction of drop-foot in common peroneal nerve palsy
    Adolfo Vigasio
    Istituto Clinico Città di Brescia Gruppo San Donato, 2 o Unità Operativa di Chirurgia della Mano e Microchirurgia Ortopedica, Via Gualla 15, 25123, Brescia, Italy
    Clin Orthop Relat Res 466:1454-66. 2008
    ....
  48. ncbi Gait deviations associated with post-stroke hemiparesis: improvement during treadmill walking using weight support, speed, support stiffness, and handrail hold
    George Chen
    Rehabilitation R and D Center 153, VA Palo Alto Health Care System, 3801 Miranda Avenue, Palo Alto, CA, USA
    Gait Posture 22:57-62. 2005
    ..We conclude that the proper selection of training parameters can improve the gait pattern practiced by individuals with hemiparesis during treadmill training and may improve treatment outcome...
  49. ncbi Freezing of gait in Parkinson's disease
    Yasuyuki Okuma
    Department of Neurology, Juntendo University Shizuoka Hospital, 1129 Nagaoka, Izunokuni, Shizuoka 410 2295, Japan
    J Neurol 253:VII27-32. 2006
    ..Deep brain stimulation of the STN often alleviates FOG in the "off" state...
  50. doi Assessment of walking performance in robot-assisted gait training: a novel approach based on empirical data
    Raphael Banz
    Balgrist University Hospital, Spinal Cord Injury Research, Zurich, Switzerland
    Conf Proc IEEE Eng Med Biol Soc 2008:1977-80. 2008
    ..A higher correlation between the subjects' walking performance and biofeedback values was found for the EDBF method compared to a theory-based biofeedback approach...
  51. doi Computerized visual feedback: an adjunct to robotic-assisted gait training
    Raphael Banz
    Spinal Cord Injury Research, Balgrist University Hospital, Zurich, Switzerland
    Phys Ther 88:1135-45. 2008
    ....
  52. doi Improving gait in multiple sclerosis using robot-assisted, body weight supported treadmill training
    Albert C Lo
    Department of Clinical Neurosciences at Brown University, Providence VA Medical Center, Providence, Rhode Island 02909 4799, USA
    Neurorehabil Neural Repair 22:661-71. 2008
    ..A promising outpatient intervention to help improve gait function with potential for addressing this treatment gap is task-repetitive gait training...
  53. ncbi The effects of pulsed auditory stimulation on various gait measurements in persons with Parkinson's Disease
    Robert L Freedland
    New York State Institute for Basic Research in Developmental Disabilities, 1050 Forest Hill Road, Staten Island, NY 10314, USA
    NeuroRehabilitation 17:81-7. 2002
    ..The results confirm prior findings that auditory stimulation can be used to positively influence the gait of persons with PD and suggest beneficial effects of ASM as an adjunct to dopaminergic therapy to treat gait dysfunctions in PD...
  54. pmc Clinical implications of gait analysis in the rehabilitation of adult patients with "Prader-Willi" Syndrome: a cross-sectional comparative study ("Prader-Willi" Syndrome vs matched obese patients and healthy subjects)
    Luca Vismara
    Physical Medicine and Rehabilitation Unit and Clinical Lab for Gait Analysis and Posture, Istituto Scientifico Ospedale San Giuseppe, Verbania, Italy
    J Neuroeng Rehabil 4:14. 2007
    ..The results were compared with those obtained in a group of obese patients and in a group of healthy subjects...
  55. ncbi Assessment of motion of a swing leg and gait rehabilitation with a gravity balancing exoskeleton
    Sunil K Agrawal
    Mechanical Systems Laboratory, Department of Mechanical Engineering, University of Delaware, Newark, DE 19716, USA
    IEEE Trans Neural Syst Rehabil Eng 15:410-20. 2007
    ..Currently, training studies are underway to assess the long-term effects of such a device on gait rehabilitation of hemiparetic stroke patients...
  56. doi The clinical spectrum of freezing of gait in Parkinson's disease
    Yasuyuki Okuma
    Department of Neurology, Juntendo University Shizuoka Hospital, Shizuoka, Japan
    Mov Disord 23:S426-30. 2008
    ..Careful observation and gait pattern analysis may lead to a successful management of individual PD patients with FOG...
  57. doi Early postoperative active mobilisation versus immobilisation following tibialis posterior tendon transfer for foot-drop correction in patients with Hansen's disease
    Santosh Rath
    LEPRA Funded Leprosy Reconstructive Surgery Unit HOINA, Muniguda, Orissa, India
    J Plast Reconstr Aesthet Surg 63:554-60. 2010
    ....
  58. ncbi Alterations in muscle activation patterns during robotic-assisted walking
    Joseph M Hidler
    Department of Biomedical Engineering, Catholic University, 620 Michigan Avenue, NE Washington, DC 20064, USA
    Clin Biomech (Bristol, Avon) 20:184-93. 2005
    ..The goal of this study was to compare the muscle activation patterns in various major leg muscles during treadmill ambulation with those exhibited during robotic-assisted walking...
  59. ncbi The use of electromyogram biofeedback to reduce Trendelenburg gait
    J S Petrofsky
    Department of Physical Therapy, School of Allied Health, Loma Linda University, CA 92350, USA
    Eur J Appl Physiol 85:491-5. 2001
    ..Subjects only undergoing clinical therapy showed about a 50% reduction in hip drop due to therapy. However, the group that used the home training device showed almost normal gait after the 2 month period...
  60. ncbi Characterization of freezing of gait subtypes and the response of each to levodopa in Parkinson's disease
    J D Schaafsma
    Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Eur J Neurol 10:391-8. 2003
    ..0001) and the number of episodes with akinesia (P < 0.001). Distinction amongst FOG subtypes enables evaluation of distinctive therapeutic response. Levodopa helps in reducing the frequency and duration of 'off'-related FOG...
  61. ncbi Falls and injuries after stroke: time for action!
    Yngve Gustafson
    Stroke 34:494-501. 2003
  62. ncbi Quantification of energy expenditure during gait in children affected by cerebral palsy
    L Piccinini
    RCCS Medea La Nostra Famiglia, Bosisio Parini LC, Italy
    Eura Medicophys 43:7-12. 2007
    ..These disabilities during deambulation may lead to excessive energy cost and so to a compromised energy efficiency...
  63. ncbi Combined task-specific training and strengthening effects on locomotor recovery post-stroke: a case study
    Katherine Sullivan
    Department of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, USA
    J Neurol Phys Ther 30:130-41. 2006
    ....
  64. ncbi Effect of walking speed changes on tibialis anterior EMG during healthy gait for FES envelope design in drop foot correction
    C A Byrne
    Biomedical Electronics Laboratory, Department of Electronic and Computer Engineering, University of Limerick, National Technological Park, Limerick, Ireland
    J Electromyogr Kinesiol 17:605-16. 2007
    ..5 for the self-selected and fastest speed, respectively. These results suggest that an FES envelope, which produces larger EMG amplitude for the TOB than the HSB, would be more appropriate at walking speeds typical of hemiplegic patients...
  65. ncbi Idiopathic toe-walking
    Aaron Babb
    Georgetown University, Washington, DC, USA
    S D Med 61:53, 55-7. 2008
    ..The following article provides an overview of the background information, differential diagnosis and treatment options for idiopathic toe-walking...
  66. ncbi Gait evaluation of a new electromechanical stance-control knee-ankle-foot orthosis
    Terris Yakimovich
    Rehabilitation Centre, Inst for Rehabilitation Res and Dev, Ottawa, Ont, Canada
    Conf Proc IEEE Eng Med Biol Soc 1:5924-7. 2006
    ..Two KAFO users experienced a reduction in pelvic obliquity and hip abduction angle abnormalities when walking with the SCKAFO compared to their prescribed KAFO...
  67. ncbi Knee biomechanics of moderate OA patients measured during gait at a self-selected and fast walking speed
    Scott C Landry
    School of Biomedical Engineering, Dalhousie University, Halifax, Canada
    J Biomech 40:1754-61. 2007
    ..The fast walks did not, however, increase or bring out any biomechanical differences between the OA and control groups that did not exist at the self-selected walks...
  68. ncbi The neuromuscular demands of toe walking: a forward dynamics simulation analysis
    Richard R Neptune
    Department of Mechanical Engineering, The University of Texas at Austin, 1 University Station C2200, Austin, TX 78712, USA
    J Biomech 40:1293-300. 2007
    ..Therefore, medical decisions concerning whether to reduce equinus should consider not only the impact on the ankle moment, but also the expected change to the plantar flexor's force generating capacity...
  69. doi Footstep adjustments used to turn during walking in Parkinson's disease
    Frances Huxham
    Centre for Clinical Research Excellence in Gait Analysis and Gait Rehabilitation, Victoria, Australia
    Mov Disord 23:817-23. 2008
    ..Differences in adjustment of step time to turn may reflect impaired locomotor timing control in subjects with PD during challenging gait tasks...
  70. ncbi Gait stability following concussion
    Tonya M Parker
    Motion Analysis Laboratory, Department of Human Physiology, University of Oregon, Eugene, OR 97403, USA
    Med Sci Sports Exerc 38:1032-40. 2006
    ..The need to identify functional impairment following a brain injury is critical to prevent reinjury during the period of recovery. However, little is known about the effect of concussion on dynamic motor function...
  71. ncbi [Gait disorders in the elderly]
    E Warzee
    Service de Geriatrie, CHU Sart Tilman, Liege, Belgique
    Rev Med Liege 62:713-8. 2007
    ..A link between cognitive and gait disorders is put forward by several recent studies. This paper is concerned with the various gait abnormalities encountered in the elderly, especially seriale gait, and the means to detect them...
  72. ncbi Gait characteristics following Achilles tendon elongation: the foot rocker perspective
    Tadeusz Bober
    University School of Physical Education, Biomechanics Laboratory, Wroclaw, Poland
    Acta Bioeng Biomech 10:37-42. 2008
    ..Foot rocker analysis identified children with abnormal gait characteristics. Following surgery these gait characteristics remained abnormal...
  73. ncbi Validity of six balance disorders scales in persons with multiple sclerosis
    Davide Cattaneo
    LaRiCE Gait and Balance Disorders Laboratory, Servizio riabilitazione neurologica adulti Int 282 Don Gnocchi Foundation, V Capecelatro 66, 20148 Milan, Italy
    Disabil Rehabil 28:789-95. 2006
    ..The aim of this study was to test concurrent and discriminant validity of several tests of static and dynamic balance in a sample of subjects suffering from MS...
  74. ncbi Neuromuscular electric stimulation effect on lower-extremity motor recovery and gait kinematics of patients with stroke: a randomized controlled trial
    Gunes Yavuzer
    Department of Physical Medicine and Rehabilitation, Ankara University Faculty of Medicine, Ankara, Turkey
    Arch Phys Med Rehabil 87:536-40. 2006
    ..To evaluate the effects of neuromuscular electric stimulation (NMES) of the tibialis anterior muscle on motor recovery and gait kinematics of patients with stroke...
  75. doi Gait analysis of donor leg after free fibular flap transfer
    J H Lee
    Department of Oral and Maxillofacial Surgery, College of Dentistry, Seoul National University, Seoul, South Korea
    Int J Oral Maxillofac Surg 37:625-9. 2008
    ..On the basis of the gait analysis results, it was concluded that normalization of the patients' gaits would be expected within 3 months after the operation. There were no permanent pathological changes in the donor site...
  76. ncbi Are patients with hereditary spastic paraplegia different from patients with spastic diplegia during walking? Gait evaluation using 3D gait analysis
    Veronica Cimolin
    Department of Bioengineering, Polytechnic of Milan, Italy
    Funct Neurol 22:23-8. 2007
    ....
  77. pmc Parallel facilitatory reflex pathways from the foot and hip to flexors and extensors in the injured human spinal cord
    Maria Knikou
    Sensory Motor Performance Program, Rehabilitation Institute of Chicago, and Department of Physical Medicine and Rehabilitation, Feinberg Medical School, Northwestern University, Chicago, IL 60611, USA
    Exp Neurol 206:146-58. 2007
    ..The interactive effects of these sensory signals may be a feature of impaired gait, but when they are appropriately excited, they may contribute to locomotion recovery in these patients...
  78. ncbi Gait pattern categorization of stroke participants with equinus deformity of the foot
    Sharon Kinsella
    Department of Science and Health, School of Science, Institute of Technology, Carlow, Ireland
    Gait Posture 27:144-51. 2008
    ..The results from this study can be used to categorise patients, facilitating appropriate development of targeted treatment...
  79. pmc Comparison of speeds used for the 15.2-meter and 6-minute walks over the year after an incomplete spinal cord injury: the SCILT Trial
    H Barbeau
    McGill University Institut de Readaptation de Montreal, Montreal, Quebec, Canada
    Neurorehabil Neural Repair 21:302-6. 2007
    ....
  80. ncbi Assessment of walking speed and distance in subjects with an incomplete spinal cord injury
    Hubertus J A van Hedel
    Spinal Cord Injury Center, Balgrist University Hospital, Zurich, Switzerland
    Neurorehabil Neural Repair 21:295-301. 2007
    ..Studies about testing preferred and maximum speeds in subjects with incomplete spinal cord injury are lacking...
  81. pmc Gait dynamics, fractals and falls: finding meaning in the stride-to-stride fluctuations of human walking
    Jeffrey M Hausdorff
    Laboratory for Gait and Neurodynamics, Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Israel
    Hum Mov Sci 26:555-89. 2007
    ....
  82. ncbi Auditory feedback control for improvement of gait in patients with Multiple Sclerosis
    Yoram Baram
    Department of Computer Science, Technion Israel Institute of Technology, Haifa, Israel
    J Neurol Sci 254:90-4. 2007
    ..To study the use of auditory feedback for gait management and rehabilitation in patients with Multiple Sclerosis (MS)...
  83. ncbi Test-retest reliability of spatial and temporal gait parameters in children with cerebral palsy as measured by an electronic walkway
    Anne Brit Sorsdahl
    Department of Public Health and Primary Health Care, Section for Physiotherapy Science, University of Bergen, N 5020, Bergen, Norway
    Gait Posture 27:43-50. 2008
    ..The purpose of this study was to examine test-retest reliability of seven selected temporal and spatial gait parameters and asymmetry measures in children with cerebral palsy...
  84. ncbi Effects of postural task requirements on the speed-accuracy trade-off
    Marcos Duarte
    Escola de Educacao Fisica e Esporte, Universidade de Sao Paulo, Av Mello de Moraes 65, Sao Paulo, SP, 05508 030, Brazil
    Exp Brain Res 180:457-67. 2007
    ..The results may have practical implications for posture and gait rehabilitation techniques that use modifications of stepping accuracy...
  85. pmc Two simple methods for determining gait events during treadmill and overground walking using kinematic data
    J A Zeni
    Department of Mechanical Engineering, Biomechanics and Movement Science Program, University of Delaware, Newark, DE, United States
    Gait Posture 27:710-4. 2008
    ..Automatic event detection from the two kinematic-based algorithms will aid researchers by accurately determining gait events during the analysis of treadmill and overground walking...
  86. ncbi Falls and gait characteristics among older persons with peripheral neuropathy
    Trina K DeMott
    Department of Physical Medicine and Rehabilitation, University of Michigan Health Systems, Ann Arbor, Michigan 48108, USA
    Am J Phys Med Rehabil 86:125-32. 2007
    ..To prospectively determine the frequency and circumstances of falls in older persons with peripheral neuropathy and to identify gait characteristics on smooth and irregular surfaces associated with falls in this same population...
  87. pmc Postural dysfunction during standing and walking in children with cerebral palsy: what are the underlying problems and what new therapies might improve balance?
    Marjorie Hines Woollacott
    Department of Human Physiology, University of Oregon, Eugene 97403, USA
    Neural Plast 12:211-9; discussion 263-72. 2005
    ..Clinical implications include the suggestion that improvement in the ability to recover balance is possible in school age children with CP...
  88. ncbi Differences in coding provided by proprioceptive and vestibular sensory signals may contribute to lateral instability in vestibular loss subjects
    John H J Allum
    Department of ORL, University Hospital, Basel, Switzerland
    Exp Brain Res 184:391-410. 2008
    ....
  89. doi Mobility beyond the clinic: the effect of environment on gait and its measurement in community-ambulant stroke survivors
    Kimberley Donovan
    School of Physiotherapy, Centre for Physiotherapy Research, University of Otago, New Zealand
    Clin Rehabil 22:556-63. 2008
    ..To explore the impact of a complex community environment on gait parameters (speed, step length and cadence) for community-dwelling participants with a previous stroke, and compare outcome measures commonly used in a clinical environment...
  90. ncbi Repeatability of lower limb three-dimensional kinematics in patients with stroke
    Gunes Yavuzer
    Department of Physical Medicine and Rehabilitation, Ankara University Faculty of Medicine, Ankara, Turkey
    Gait Posture 27:31-5. 2008
    ..4. The results indicate that time-distance parameters and sagittal plane gait kinematics of the paretic lower limb, measured by the Vicon 370 gait analysis system, are repeatable and can be used to assess treatment effects after stroke...
  91. ncbi Botulinum toxin type B for gait freezing in Parkinson's disease
    Hubert H Fernandez
    Department of Clinical Neuroscience, Brown University School of Medicine, Providence, RI, USA
    Med Sci Monit 10:CR282-4. 2004
    ..Freezing of Gait (FOG) can be a serious problem in Parkinson's disease (PD) and is usually refractory to medical treatment. Botulinum toxin (BTX) type A has been reported to relieve FOG in small open label studies...
  92. ncbi Temporal differences in relative phasing of gait initiation and first step length in patients with cervical and lumbosacral spinal cord injuries
    H A Chang
    Department of Physical Medicine and Rehabilitation, National Yang Ming University, Taiwan
    Spinal Cord 42:281-9. 2004
    ..Comparison group design...
  93. pmc Gait unsteadiness and fall risk in two affective disorders: a preliminary study
    Jeffrey M Hausdorff
    Division on Aging, Harvard Medical School, Boston, MA, USA
    BMC Psychiatry 4:39. 2004
    ....
  94. ncbi Motor imagery for gait rehabilitation in post-stroke hemiparesis
    Ruth Dickstein
    Department of Physical Therapy, Faculty of Social Welfare and Health Studies, The University of Haifa, Mount Carmel, Haifa 31905, Israel
    Phys Ther 84:1167-77. 2004
    ..The purpose of this case report is to describe the use of MI practice to attempt to improve walking in an individual with hemiparesis...
  95. ncbi Two methods of calculating thorax kinematics in children with myelomeningocele
    Tam C Nguyen
    Hugh Williamson Gait Laboratory, Royal Children s Hospital, Melbourne, Victoria, Australia
    Clin Biomech (Bristol, Avon) 19:1060-5. 2004
    ..The purpose of this study was to determine the importance of model and cardan angle sequence for calculating thorax kinematics...
  96. ncbi Dynamic resources used in ambulation by children with spastic hemiplegic cerebral palsy: relationship to kinematics, energetics, and asymmetries
    Sergio T Fonseca
    Departamento de Fisioterapia, Universidade Federal de Minas Gerais, Av Antõnio Carlos 6627 Unidade Administrativa II, 31270 010, Belo Horizonte, Minas Gerais, Brazil
    Phys Ther 84:344-54; discussion 355-8. 2004
    ..The purpose of this study was to explore how the requirements of the task and the energy-generating and energy-conserving capabilities of children with cerebral palsy relate to kinematic and mechanical energy patterns of walking...
  97. ncbi Effects of bilateral subthalamic stimulation on gait kinematics and kinetics in Parkinson's disease
    M Ferrarin
    Centro di Bioingegneria FDG, Fond Don Carlo Gnocchi ONLUS IRCCS, Milan, Italy
    Exp Brain Res 160:517-27. 2005
    ..Given the additive and synergistic effects, it can be hypothesized that the two treatments have different mechanisms of action. Our results confirm the findings of earlier studies that employed treadmill walking...
  98. ncbi Modified emory functional ambulation profile: an outcome measure for the rehabilitation of poststroke gait dysfunction
    H R Baer
    Department of Rehabilitation Medicine, Center for Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA, USA
    Stroke 32:973-9. 2001
    ..145). Total mEFAP and all mEFAP subtask scores improved over time (P:<0.0001). CONCLUSIONS: The mEFAP is a reliable gait-assessment tool for patients with stroke and is sensitive to change in ambulation speed...
  99. ncbi Evidence for a disorder of locomotor timing in Huntington's disease
    Belinda Bilney
    School of Physiotherapy, La Trobe University, Victoria, Australia
    Mov Disord 20:51-7. 2005
    ..The exact neural correlates of this timing disorder are yet to be determined...
  100. ncbi Is freezing of gait in Parkinson's disease related to asymmetric motor function?
    Meir Plotnik
    Movement Disorders Unit, Department of Neurology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Ann Neurol 57:656-63. 2005
    ..Taken together, the results of this study suggest that bilateral uncoordinated gait and marked gait asymmetry, but not asymmetry in motor performance in general, are associated with FOG...
  101. ncbi Gait outcomes after additional backward walking training in patients with stroke: a randomized controlled trial
    Yea Ru Yang
    Institute and Faculty of Physical Therapy, National Yang Ming University, Shih Pai, Taipei, Taiwan
    Clin Rehabil 19:264-73. 2005
    ..To examine the effectiveness of additional backward walking training on gait outcome of patients post stroke...

Research Grants68

  1. REHABILITATION OF SPASTIC STIFF-LEGGED GAIT
    D Kerrigan; Fiscal Year: 1999
    ..This study should provide useful, specific therapeutic options, based upon valid scientific data, as well as a more comprehensive understanding of spastic gait in general. ..
  2. Novel Treatment for Parkinson's Disease
    Dale Christensen; Fiscal Year: 2007
    ..Success in development of new therapeutics will also provide for a potentially significant increase in quality of life for affected patients and their families. [unreadable] [unreadable] [unreadable]..
  3. Dopamine Neuron Protection by Macrophage GDNF Delivery
    Senlin Li; Fiscal Year: 2005
    ..The study will serve as a basis for developing vectors for potential use in patients with neurodegenerative diseases. ..
  4. Latent Mobility Abnormalities and Disability
    Joe Verghese; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  5. Mechanical Intervention in Children with Cerebral Palsy
    Tishya Wren; Fiscal Year: 2005
    ..This study will also provide insight into the potential role of muscle adaptation and bone turnover in increasing bone mass in response to this simple, non-invasive, non-pharmacalogical intervention. ..
  6. Impact of Gait Analysis on Surgical Outcomes
    Tishya Wren; Fiscal Year: 2009
    ..The results will determine whether the use of gait analysis testing improves clinical outcomes in children who have walking problems due to cerebral palsy. ..
  7. Efferent Vestibular Mechanisms
    MEIR PLOTNIK PELEG; Fiscal Year: 2003
    ..The significance of this research is in setting the foundations of mammalian efferent neuron physiology, and providing experimental data on the control mechanism by which the EVS operates. ..
  8. Novel Brain Neuroimaging Markers of Age-Related Mobility Impairment
    Caterina Rosano; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  9. Global vs. Focal Neuroimaging Markers of Dementia Risk
    Caterina Rosano; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  10. Long-term Ambulatory Gait Monitor for Parkinson's Disease
    Steven Moore; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  11. PERIPHERAL NEUROPATHY, SENSORIMOTOR FUNCTIONS & BALANCE
    James Richardson; Fiscal Year: 2004
    ..Stratification of the subjects in the first group by the presence of carpal tunnel syndrome and testing the subjects in the second group at 3 and 12 weeks may give insight into the mechanisms responsible for improvement noted. ..
  12. Risk Factors and the Neurobiologic Substrate of Frailty
    Aron Buchman; Fiscal Year: 2009
    ..abstract_text> ..
  13. fMRI Predictor Model for Stroke Locomotor Rehabilitation
    Bruce Dobkin; Fiscal Year: 2008
    ..The study is a step toward using fMRI as a tool to develop theory- and evidencebased practices that lessen disabilities after stroke. [unreadable] [unreadable] [unreadable]..
  14. Neurobiologic Study of Psychological Distress & Dementia
    Robert S Wilson; Fiscal Year: 2010
    ....
  15. Complementary/Alternative Medicine for Vestibulopathy
    David Krebs; Fiscal Year: 2002
    ..The latter aim is purely exploratory and descriptive in nature. ..
  16. Virtual Reality Augmented Cycling for Post-Stroke Mobility Rehabilitation
    Judith Deutsch; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  17. Tracking Fatigue-Related Changes in Motor Coordination
    JONATHAN DINGWELL; Fiscal Year: 2006
    ..We hope these efforts will one day help reduce the tremendous monetary and personal costs associated with these injuries [unreadable] [unreadable]..
  18. Electrophysiology: Integrating Modalities and Discipline
    Nashaat Boutros; Fiscal Year: 2008
    ..Both career awards and travel grants will be offered for young investigators to attend the conference. This is again designed to facilitate the interaction between established and new investigators. [unreadable] [unreadable]..
  19. Nonparametric Inference for Neuroimaging Data
    Timothy Johnson; Fiscal Year: 2008
    ..abstract_text> ..
  20. Biomechanical Causes of Slow Gait in the Elderly
    DARRYL THELEN; Fiscal Year: 2006
    ..The results of this study are fundamental to the development of effective interventions that can improve gait function and thereby contribute to the maintenance of mobility in elderly adults [unreadable] [unreadable]..
  21. COMPELLED BODY WEIGHT SHIFT THERAPY IN INDIVIDUALS WITH STROKE
    Alexander Aruin; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  22. Sensory Gating Mediated by Attention
    Patricia Davies; Fiscal Year: 2007
    ..Improved measures of sensory gating may lead to productive and cost efficient studies assessing treatment effectiveness. [unreadable] [unreadable] [unreadable]..
  23. Role of Auxiliary Sensory Cues on Balance in Peripheral Neuropathy
    Alexander Aruin; Fiscal Year: 2008
    ..The project will provide preliminary data on the role auxiliary sensory cues play in the balance of individuals with peripheral neuropathy. [unreadable] [unreadable] [unreadable]..
  24. OCULOMOTOR CONTROL AND GAIT IN PARKINSON DISEASE
    Gammon M Earhart; Fiscal Year: 2010
    ..Using the knowledge gained, we aim to develop innovative gait rehabilitation approaches for individuals with PD with the ultimate goal of reducing falls and hip fractures in this population. ..
  25. Biocomputation of the Links Between Muscle Morphology, Coordination and Injury
    DARRYL G contact THELEN; Fiscal Year: 2010
    ..This proposal couples novel biocomputational tools and imaging techniques to establish a scientific basis for preventing and rehabilitating hamstring muscle injuries. ..
  26. Shoulder Pain in Spinal Cord Injury (SCI): A Longitudinal Study
    Sara J Mulroy; Fiscal Year: 2010
    ..MANOVA will be employed to compare the biomechanical parameters of WCP for the shoulder pain and pain-free groups. ..
  27. Neural basis of heritable DA-mediated gating deficits
    Neal R Swerdlow; Fiscal Year: 2010
    ....
  28. Development of a SimTK-based framework for hemiparetic walking assessment
    Richard R Neptune; Fiscal Year: 2010
    ....
  29. Diagnostic Error in Dystonia
    Caroline M Tanner; Fiscal Year: 2010
    ..If successful, this approach could be applied in other medical care settings, as well as for other rare disorders, to improve medical care and efficiency, and reduce suffering. ..
  30. Re-training locomotor circuitry in a rat model of Spinal Cord Injury
    David S K Magnuson; Fiscal Year: 2010
    ..In addition, we will begin to look at the mechanisms of rehabilitation associated plasticity using a custom made array to detect changes in mRNA levels in spinal cord tissue following different training protocols. ..
  31. CORTICO-STRIATAL SUBSTRATES OF DEFICIENT STARTLE GATING
    Neal R Swerdlow; Fiscal Year: 2010
    ..New information from these studies will be a foundation for innovative models of the pathophysiology of schizophrenia and other inherited neuropsychiatric disorders, and for prospective strategies for novel drug development. ..
  32. Locomotor Experience Applied Post-Stroke (LEAPS)
    Pamela Duncan; Fiscal Year: 2009
    ..Our ultimate goal is to provide evidence to guide post-stroke rehabilitation practice and reduce disability in persons post-stroke. ..
  33. A Novel Animal Model of Relevance to Schizophrenia
    David Feifel; Fiscal Year: 2009
    ..The successful development of this animal model could significantly enhance the understanding of the underlying causes of schizophrenia-associated abnormalities and improve drug discovery. ..
  34. rTMS and Motor Learning Training to Promote Recovery from Hemiparesis
    James Carey; Fiscal Year: 2009
    ..The potential impact of this research is a radical change to rehabilitation that accomplishes a higher quality of life in stroke. ..
  35. VIRTUAL REALITY IN BALANCE DISORDERS
    Susan Whitney; Fiscal Year: 2007
    ..The data derived from the above three goals will help direct a randomized clinical trial that will assist in determining if virtual reality is an effective method of intervention with persons with vestibular dysfunction. ..
  36. Treatment of Motor Function and Balance- A New Tool
    Lars Oddsson; Fiscal Year: 2006
    ..abstract_text> ..
  37. PharmaScan 70/16 In-Vivo Spectroscopy/Imaging System
    Ranu Jung; Fiscal Year: 2005
    ..abstract_text> ..
  38. ORGANIZATION OF ANTICIPATORY POSTURAL ADJUSTMENTS
    Alexander Aruin; Fiscal Year: 2002
    ..Clinical application of the results of the study will define more precisely the focus of conventional rehabilitation strategies aimed at improving postural control in people with postural deficits. ..
  39. Prenatal Corticosteroid Impact on Hippocampus
    LIBOR VELISEK; Fiscal Year: 2004
    ..The data of this proposal will be critical for determining long-term adverse effects of multiple course prenatal corticosteroid therapy and for the ameliorating these effects in the offspring. ..
  40. QUANTITATIVE FUNCTION IN MOTOR NEURON DISEASE
    Eric Sorenson; Fiscal Year: 2004
    ..This will become increasingly important as our population ages, increasing demands for medical and social resources. ..
  41. ALCOHOL, HIV, AND THE BRAIN
    Adolf Pfefferbaum; Fiscal Year: 2004
    ..Specific Aim 3: To establish cross-sectional and longitudinal within-subject relationships among nueroimaging, neuropsychological, and clinical measures. ..
  42. Effects of Stress on Pathology of Parkinson's Disease
    GERLINDE METZ; Fiscal Year: 2004
    ..These approaches will provide the opportunity to understand factors involved in the pathology of PD and to develop novel therapeutic strategies for neurodegenerative motor disorders. ..
  43. Duration and Timing of Supported Treadmill Training
    Pamela Duncan; Fiscal Year: 2003
    ..The long-term objective is to improve the ability to walk in individuals following stroke by providing clinical practice guidelines, based on scientific evidence, for the optimal use of BWSTT in rehabilitation. ..
  44. INTERVENTIONS FOR SCI SHOULDER FUNCTION IN WHEELCHAIRS
    Sara Mulroy; Fiscal Year: 2004
    ..Statistical significance of the findings will be determined by repeated measures MANOVA analyses with grouping factors for SCI level and exercise/control groups. ..
  45. PANDAS and Strep Infection: Are they Linked?
    Roger Kurlan; Fiscal Year: 2004
    ..Disproving the PANDAS hypothesis would prevent the use of expensive and potentially dangerous therapies (e.g., plasma exchange, immune globulin, antibiotics) that have been proposed for PANDAS patients. ..
  46. HIV Neuroprotection Workshop
    Joseph Berger; Fiscal Year: 2004
    ..The proposed conference is the first of its kind to highlight neuroprotection in HIV CNS and PNS disorders. By coupling this meeting with the International Symposium on Neurovirology this synergy can be exploited. ..
  47. Neuroscience at the Boundaries of Neurology and Psychiatry
    Neal Swerdlow; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  48. GENETICS OF PARKINSON DISEASE IN THE AMISH
    Brad Racette; Fiscal Year: 2006
    ..abstract_text> ..
  49. Comparison of post-SCI locomotor training techniques
    EDELLE FIELD FOTE; Fiscal Year: 2006
    ..In addition, they will provide information about neural and cardiorespiratory bases of these functional changes. ..
  50. Robotically Generated Locomotion in Rodents
    V Edgerton; Fiscal Year: 2002
    ..These data will also provide insight into development of body weight support control and manual (or robotic) intervention for human locomotor training. ..
  51. Antipsychotic-Like Drug Effects of Neurotensin
    David Feifel; Fiscal Year: 2004
    ....
  52. NEURAL CIRCUITRY OF SENSORIMOTOR GATING ACROSS SPECIES
    Neal Swerdlow; Fiscal Year: 2006
    ....
  53. Cortical Excitability in Cocaine-Dependent Subjects
    Nashaat Boutros; Fiscal Year: 2006
    ..A normal control group will be included. The TMS measured motor threshold and length of the TMS induced silent periods will be compared between the three groups. ..
  54. Parkin mutations and their functional consequences
    Alexis Brice; Fiscal Year: 2005
    ....
  55. SEXUAL DIMORPHISM IN SEIZURE CONTROL
    JANA VELISKOVA; Fiscal Year: 2002
    ..Rats of both sexes and various ages will be used. These studies may lead to the development of new antiepileptic treatments that take into the account sexual age-related differences. ..
  56. Skin Pigmentation and Parkinson's Disease Risk
    Caroline Tanner; Fiscal Year: 2003
    ..This could be an enormous breakthrough in our understanding of factors that influence the risk (and perhaps even the cause) of Parkinson's disease, and could lead to new strategies for disease prevention. ..
  57. VESTIBULAR SOMATOSENSORY INTERACTIONS FOR HUMAN POSTURE
    Fay Horak; Fiscal Year: 2002
    ....
  58. JCV Virus Expression in Oropharynx and HIV
    Joseph Berger; Fiscal Year: 2004
    ..This line of investigation would add credence to an oropharyngeal mechanism of JCV transmission and may ultimately lead to the clinical identification of an acute illness attributable to this pathogen. ..
  59. PESTICIDES AND RISK IN THE AGRICUTURAL HEALTH STUDY
    Caroline Tanner; Fiscal Year: 2004
    ..The investigators believe that this work could provide a critical and dramatic next step in furthering our knowledge of environmental determinants of PD, and thereby take us closer to our goal of finding its cause(s). ..
  60. PERIPHERAL AND CENTRAL POSTURAL DISORDERS IN THE ELDERLY
    Fay Horak; Fiscal Year: 2003
    ..abstract_text> ..
  61. Epidemiology of Dystonia in a Multi-Ethnic Population
    Caroline Tanner; Fiscal Year: 2009
    ..In addition, this cohort will provide a rich resource for future investigations including family studies, genetic analyses and further investigations of environmental risk factors. ..
  62. A Rodent Model for Locomotor Training with FNS
    Ranu Jung; Fiscal Year: 2004
    ..This locomotor training could also be combined with pharmacological intervention, tissue transplant, and neural repair therapies to determine if locomotor training can enhance the effectiveness of these therapies. ..
  63. CRCNS: Modeling Neuromusculoskeletal Alterations after Spinal Cord Injury
    Ranu Jung; Fiscal Year: 2008
    ..abstract_text> ..
  64. GAIT INSTABILITY IN THE ELDERLY WITH INCREASED FALL RISK
    Jeffrey Hausdorff; Fiscal Year: 2008
    ..abstract_text> ..
  65. PHASE RESETTING AND SENSORY INHIBITION IN THE CNS
    Nashaat Boutros; Fiscal Year: 2005
    ....
  66. Adaptation of Spatial Orientation in Locomotion and Posture
    FAY BAHLING HORAK; Fiscal Year: 2010
    ..abstract_text> ..