cerebrospinal fluid rhinorrhea

Summary

Summary: Discharge of cerebrospinal fluid through the nose. Common etiologies include trauma, neoplasms, and prior surgery, although the condition may occur spontaneously. (Otolaryngol Head Neck Surg 1997 Apr;116(4):442-9)

Top Publications

  1. ncbi Nontraumatic skull base defects with spontaneous CSF rhinorrhea and arachnoid herniation: imaging findings and correlation with endoscopic sinus surgery in 27 patients
    B Schuknecht
    MRI Medical Radiological Institute Zurich, Bethanien Clinic and Bahnhofplatz, Zurich, Switzerland
    AJNR Am J Neuroradiol 29:542-9. 2008
  2. ncbi Endoscopic endonasal approaches for repair of cerebrospinal fluid leaks: nine-year experience
    Davide Locatelli
    Department of Neurosurgery, Science Research and Cure Institute Policlinico S Matteo, University of Pavia, Pavia, Italy
    Neurosurgery 58:ONS-246-56; discussiom ONS-256-7. 2006
  3. ncbi Endoscopic endonasal approaches to anterior skull base defects in pediatric patients
    Davide Locatelli
    Department of Neurosurgery, IRCCS Policlinico S Matteo, University of Pavia, 27100, Pavia, Italy
    Childs Nerv Syst 22:1411-8. 2006
  4. ncbi Nonsurgical cerebrospinal fluid rhinorrhea in invasive macroprolactinoma: incidence, radiological, and clinicopathological features
    S G I Suliman
    Department of Endocrinology, Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford OX3 7LJ, United Kingdom
    J Clin Endocrinol Metab 92:3829-35. 2007
  5. ncbi Spontaneous cerebrospinal fluid rhinorrhea as the presenting symptom of sellar pathologies: three demonstrative cases
    Stefano Telera
    Division of Neurosurgery, Regina Elena, National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy
    Neurosurg Rev 30:78-82; discussion 82. 2007
  6. ncbi Cerebrospinal fluid rhinorrhea: diagnosis and management
    Julie T Kerr
    Department of Otolaryngology Head and Neck Surgery, Madigan Army Medical Center, Tacoma, WA, USA
    Otolaryngol Clin North Am 38:597-611. 2005
  7. ncbi Persistent cerebrospinal fluid rhinorrhea by intrasphenoidal encephalocele
    E Peltonen
    Department of Neurosurgery Campus Benjamin Franklin, Charite Universitatsmedizin Berlin, Germany
    Zentralbl Neurochir 69:187-90. 2008
  8. ncbi Delayed cerebrospinal fluid rhinorrhea after gamma knife surgery in a patient with a growth hormone-secreting adenoma
    Yan Hongmei
    Beijing Institute of Functional Neurosurgery, Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Avenue, Xicheng District, Beijing 100053, China
    J Clin Neurosci 19:900-2. 2012
  9. ncbi Two consecutive cases of cerebrospinal fluid rhinorrhea after septoplasty operation
    T Metin Onerci
    Department of Otorhinolaryngology Head and Neck Surgery, Hacettepe University, Ankara, Turkey
    Am J Otolaryngol 25:354-6. 2004
  10. ncbi Safety and efficacy of endoscopic repair of CSF leaks and encephaloceles: a survey of the members of the American Rhinologic Society
    B A Senior
    Department of Otolaryngology/Head and Neck Surgery, Henry Ford Hospital, Detroit, Michigan, USA
    Am J Rhinol 15:21-5. 2001

Research Grants

Detail Information

Publications227 found, 100 shown here

  1. ncbi Nontraumatic skull base defects with spontaneous CSF rhinorrhea and arachnoid herniation: imaging findings and correlation with endoscopic sinus surgery in 27 patients
    B Schuknecht
    MRI Medical Radiological Institute Zurich, Bethanien Clinic and Bahnhofplatz, Zurich, Switzerland
    AJNR Am J Neuroradiol 29:542-9. 2008
    ..The purpose of our study was to correlate CT and MR findings regarding the location and content of CSF leaks in 27 patients with endoscopic sinus surgery observations...
  2. ncbi Endoscopic endonasal approaches for repair of cerebrospinal fluid leaks: nine-year experience
    Davide Locatelli
    Department of Neurosurgery, Science Research and Cure Institute Policlinico S Matteo, University of Pavia, Pavia, Italy
    Neurosurgery 58:ONS-246-56; discussiom ONS-256-7. 2006
    ..To describe surgical endoscopic experience in the repair of cerebrospinal fluid leaks treated by transnasal approaches...
  3. ncbi Endoscopic endonasal approaches to anterior skull base defects in pediatric patients
    Davide Locatelli
    Department of Neurosurgery, IRCCS Policlinico S Matteo, University of Pavia, 27100, Pavia, Italy
    Childs Nerv Syst 22:1411-8. 2006
    ..All subjects underwent surgery owing to progressive symptoms. The endoscopic endonasal approach is a new method in the treatment of this pathology in children...
  4. ncbi Nonsurgical cerebrospinal fluid rhinorrhea in invasive macroprolactinoma: incidence, radiological, and clinicopathological features
    S G I Suliman
    Department of Endocrinology, Oxford Centre for Diabetes, Endocrinology, and Metabolism, Churchill Hospital, Oxford OX3 7LJ, United Kingdom
    J Clin Endocrinol Metab 92:3829-35. 2007
    ..Macroprolactinomas (MPRLs) may result in nonsurgical (spontaneous or dopamine agonist induced) cerebrospinal fluid (CSF) rhinorrhea; however, the incidence of and mechanisms underlying this phenomenon are poorly understood...
  5. ncbi Spontaneous cerebrospinal fluid rhinorrhea as the presenting symptom of sellar pathologies: three demonstrative cases
    Stefano Telera
    Division of Neurosurgery, Regina Elena, National Cancer Institute, Via Elio Chianesi 53, 00144 Rome, Italy
    Neurosurg Rev 30:78-82; discussion 82. 2007
    ..The present paper reports three unusual cases of sellar pathologies revealed by rhinorrhea as the first symptom discussing controversial issues on pathogenesis, complications and current management of this kind of fistula...
  6. ncbi Cerebrospinal fluid rhinorrhea: diagnosis and management
    Julie T Kerr
    Department of Otolaryngology Head and Neck Surgery, Madigan Army Medical Center, Tacoma, WA, USA
    Otolaryngol Clin North Am 38:597-611. 2005
    ..With expanded reconstructive techniques, the ability to handle larger disease processes of the skull base continues to expand...
  7. ncbi Persistent cerebrospinal fluid rhinorrhea by intrasphenoidal encephalocele
    E Peltonen
    Department of Neurosurgery Campus Benjamin Franklin, Charite Universitatsmedizin Berlin, Germany
    Zentralbl Neurochir 69:187-90. 2008
    ..The pathogenesis of this anomaly is analyzed, the clinical findings and the operative treatment are described, and the literature is reviewed...
  8. ncbi Delayed cerebrospinal fluid rhinorrhea after gamma knife surgery in a patient with a growth hormone-secreting adenoma
    Yan Hongmei
    Beijing Institute of Functional Neurosurgery, Department of Functional Neurosurgery, Xuanwu Hospital, Capital Medical University, 45 Changchun Avenue, Xicheng District, Beijing 100053, China
    J Clin Neurosci 19:900-2. 2012
    ..The other potential causes may be the original invasiveness of the tumor or delayed radiation damage to the mucous membranes of the skull. Long-term follow-up is required to monitor recurrence of CSF rhinorrhea...
  9. ncbi Two consecutive cases of cerebrospinal fluid rhinorrhea after septoplasty operation
    T Metin Onerci
    Department of Otorhinolaryngology Head and Neck Surgery, Hacettepe University, Ankara, Turkey
    Am J Otolaryngol 25:354-6. 2004
    ..Prevention of the CSF fistula in septoplasty is more important than its treatment. Realizing the anatomic variations and gentle manipulation at the ethmoid roof is essential...
  10. ncbi Safety and efficacy of endoscopic repair of CSF leaks and encephaloceles: a survey of the members of the American Rhinologic Society
    B A Senior
    Department of Otolaryngology/Head and Neck Surgery, Henry Ford Hospital, Detroit, Michigan, USA
    Am J Rhinol 15:21-5. 2001
    ..Overall, our results confirm that in the hands of the skilled endoscopist, endoscopic management of CSF leaks and encephaloceles is highly efficacious and has a very low incidence of significant complication...
  11. ncbi Spontaneous cerebrospinal fluid rhinorrhoea due to temporosphenoidal encephalocele
    Kerem Bikmaz
    Social Security Okmeydani Training Hospital, Istanbul, Turkey
    J Clin Neurosci 12:827-9. 2005
    ..Spontaneous CSF rhinorrhoea is only infrequently due to temporal encephalocele. Anteromedial temporosphenoidal encephaloceles are the least common type of temporal encephalocele, with only 12 reported in the literature...
  12. ncbi New techniques and technology to repair cerebrospinal fluid rhinorrhea
    G Paludetti
    Institute of Otolaryngology, Catholic University of Sacred Heart, Rome, Italy
    Acta Otorhinolaryngol Ital 24:130-6. 2004
    b>Cerebrospinal fluid rhinorrhea occurs as a result of abnormal communication between the subarachnoid space and the pneumatized portion of the skull base, the paranasal sinuses and the middle ear...
  13. ncbi The "yo-yo" technique to prevent cerebrospinal fluid rhinorrhea after anterior clinoidectomy for proximal internal carotid artery aneurysms
    John H Chi
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California 94143 0112, USA
    Neurosurgery 59:ONS101-7; discussion ONS101-7. 2006
    ..We present a technique for repairing this defect and preventing CSF rhinorrhea...
  14. ncbi Intraoperative emergencies during endoscopic sinus surgery: CSF leak and orbital hematoma
    Kevin C Welch
    Department of Otorhinolaryngology, Division of Rhinology, University of Pennsylvania Health System, 5 Ravdin, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Otolaryngol Clin North Am 41:581-96, ix-x. 2008
    ..Intraoperative orbital hematoma is discussed and a stepwise approach to reduce complications is provided...
  15. ncbi Spontaneous cerebrospinal fluid rhinorrhea associated with a far lateral temporal encephalocele--case report
    Atsushi Arai
    Department of Neurosurgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan
    Neurol Med Chir (Tokyo) 50:243-5. 2010
    ..At 1-year follow up, the CSF rhinorrhea had not recurred. Transcranial multilayered closure of the defect is safe and reliable, particularly for large CSF fistula at the far lateral sphenoid sinus...
  16. ncbi Transnasal endoscopic repair of cerebrospinal fluid rhinorrhea and skull base defect: ten-year experience
    Ta Jen Lee
    Department of Otorhinolaryngology, Chang Gung Memorial Hospital, Chang Gung University, Linkou, Taiwan
    Laryngoscope 114:1475-81. 2004
    ..This study determined the effectiveness of endoscopic repair of CSF leaks and interpreted the indications of the lumbar drain...
  17. pmc A new nephelometric assay for beta-trace protein (prostaglandin D synthase) as an indicator of liquorrhoea
    H F Petereit
    Klinik und Poliklinik fur Neurologie und Psychiatrie, Josef Stelzmann Strasse 9, D 50924 Koln, Germany
    J Neurol Neurosurg Psychiatry 71:347-51. 2001
    ..To determine the sensitivity and specificity of a nephelometric beta-trace protein assay for the diagnosis of liquorrhoea...
  18. ncbi Cerebrospinal fluid rhinorrhoea: diagnosis and management
    Allan Abuabara
    Health Division, Joinville City Hall, Joinville, Santa Catarina, Brazil
    Med Oral Patol Oral Cir Bucal 12:E397-400. 2007
    ..The timing for surgery and CSF drainage procedures must be decided with great care and with a clear strategy...
  19. ncbi Management of cerebrospinal fluid rhinorrhea: the Medical College of Wisconsin experience
    D Richard Lindstrom
    Division of Rhinology and Sinus Surgery, Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, WI, USA
    Laryngoscope 114:969-74. 2004
    ..The purpose of this comprehensive retrospective study is to assess issues related to the management of skull base defects associated with CSF rhinorrhea involving the nose and paranasal sinuses...
  20. ncbi Endoscopic repair of cerebrospinal fluid rhinorrhea: learning from our failures
    P Castelnuovo
    Department of Otorhinolaryngology, University of Pavia, Italy
    Am J Rhinol 15:333-42. 2001
    ..The analysis of cases of failure shows that the majority of authors omit details. More research is needed to improve prevention of failures...
  21. ncbi Elevated intracranial pressures in spontaneous cerebrospinal fluid leaks
    Rodney J Schlosser
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA
    Am J Rhinol 17:191-5. 2003
    ..We present clinical and radiographic evidence that indicates elevated ICP in this group. In addition, we review the pathophysiology and unique management issues in caring for patients with spontaneous CSF leak...
  22. ncbi Risk factors of cerebrospinal fluid rhinorrhea following transsphenoidal surgery
    H Nishioka
    Department of Neurosurgery, Tokyo Medical University, Japan
    Acta Neurochir (Wien) 147:1163-6; discussion 1166. 2005
    ..Cerebrospinal fluid (CSF) rhinorrhea is a potentially life-threatening complication following transsphenoidal surgery (TSS)...
  23. ncbi Endoscopic CSF leak repair
    Timothy J Martin
    Department of Otolaryngology and Communication Sciences, Division of Rhinology, Medical College of Wisconsin, Milwaukee, Wisconsin 53226, USA
    Curr Opin Otolaryngol Head Neck Surg 15:35-9. 2007
    ..The purpose of this review is to discuss endoscopic management of cerebrospinal fluid leaks and to highlight recent advances in both outcomes and technique...
  24. ncbi Brain sag as a cause of postoperative neurological deterioration following anterior cranial fossa floor repair for post traumatic cerebrospinal fluid rhinorrhoea
    A A Kamat
    Department of Neurosurgery, Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Trust, Sheffield, South Yorkshire, UK
    Br J Neurosurg 21:303-6. 2007
    ..Absence of an initial dramatic response to treatment does not necessarily imply poor outcome in the long term...
  25. ncbi Spontaneous CSF leaks: a paradigm for definitive repair and management of intracranial hypertension
    Bradford A Woodworth
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104 4206, USA
    Otolaryngol Head Neck Surg 138:715-20. 2008
    ..To report our outcomes with the repair of spontaneous cerebrospinal fluid (CSF) leaks and to demonstrate how management of underlying intracranial hypertension improves outcomes...
  26. ncbi Repair of intractable cerebrospinal fluid rhinorrhea with mucosal flaps and recombinant human basic fibroblast growth factor: technical case report
    Shigeki Kubo
    Department of Neurosurgery, Tominaga Hospital, Osaka, Japan
    Neurosurgery 56:E627; discussion E627. 2005
    ....
  27. ncbi Endoscopic CSF rhinorrhea closure: our experience in 267 cases
    Milind V Kirtane
    Department of ENT and Head Neck Surgery, Seth GS Medical College and KEM Hospital, Parel, Mumbai, India
    Otolaryngol Head Neck Surg 132:208-12. 2005
    The advances in endoscopic sinus surgery have made it the procedure of choice for treatment of cerebrospinal fluid rhinorrhea (CSFR). To analyze the efficacy of endoscopic closure of CSFR was the objective of the present study.
  28. ncbi The management of cerebrospinal fluid leaks in patients at risk for high-pressure hydrocephalus
    Ricardo L Carrau
    Departments of Otolaryngology and Neurosurgery, University of Pittsburgh School of Medicine, The Center for Cranial Base Surgery, University of Pittsburgh Medical Center, Pennsylvania, USA
    Laryngoscope 115:205-12. 2005
    ..Patients at high risk for high-pressure hydrocephalus include those who have had a subarachnoid hemorrhage as a result of trauma (accidental or surgical) or stroke and those with spontaneous CSF leaks...
  29. ncbi Extensive tension pneumocephalus complicating continuous lumbar CSF drainage for the management of CSF rhinorrhoea
    S Mirza
    University Department of Otolaryngology, Head and Neck Surgery, Manchester Royal Infirmary, Manchester, UK
    ORL J Otorhinolaryngol Relat Spec 65:215-8. 2003
    ..The prevention and management of pneumocephalus secondary to continuous lumbar CSF drainage is briefly reviewed...
  30. ncbi Management of unexpected cerebrospinal fluid leak during endoscopic sinus surgery
    Michael P Platt
    Department of Otolaryngology, Head and Neck Surgery, Boston University, Boston, Massachusetts, USA
    Curr Opin Otolaryngol Head Neck Surg 17:28-32. 2009
    ..The purpose of this review is to outline the recent advances in the management of cerebrospinal fluid leaks that occur during endoscopic sinus surgery...
  31. ncbi Spontaneous cerebrospinal fluid rhinorrhoea and pneumocephalus following temporal lobectomy for epilepsy
    H Ellamushi
    Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, London, UK
    Br J Neurosurg 14:565-7. 2000
    ..CT revealed marked intraventricular pneumocephalus with breached air cells in the pneumatized lower part of temporal bone. The dural and bony defects repaired successfully with complete resolution of the pneumocephalus...
  32. ncbi Traumatic, iatrogenic, and spontaneous cerebrospinal fluid (CSF) leak: endoscopic repair
    J J M Daele
    University of Liege, Belgium
    B-ENT 7:47-60. 2011
    ..Recent reports in the literature highlight the group of patients with spontaneous idiopathic CSF leak as a group with specific attributes and treatment challenges...
  33. ncbi Spontaneous CSF leaks: factors predictive of additional interventions
    Rahul Seth
    Head and Neck Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Laryngoscope 120:2141-6. 2010
    ..The study objective was to review management strategy and identify factors associated with need for acetazolamide and/or ventriculoperitoneal shunt (VPS) placement...
  34. ncbi Closure of cerebrospinal fluid leaks prevents ascending bacterial meningitis
    Manuel Bernal-Sprekelsen
    Department of Otorhinolaryngology, University Hospital Clinic, Barcelona, Spain
    Rhinology 43:277-81. 2005
    ..Closure of the leaks is believed to prevent ascending meningitis, although no report has specifically shown this...
  35. ncbi 10 pearls for safe endoscopic skull base surgery
    Madeleine R Schaberg
    Department of Otolaryngology, Weill Medical College of Cornell University, New York Presbyterian Hospital, 1305 York Avenue, Fifth Floor, New York, NY 10065, USA
    Otolaryngol Clin North Am 43:945-54. 2010
    ..This article presents the 10 most important tenets that have proved useful to the authors regarding postoperative patient management and surgical practice...
  36. ncbi The efficacy of computer assisted surgery in the endoscopic management of cerebrospinal fluid rhinorrhea
    Abtin Tabaee
    Department of Otorhinolaryngology Head and Neck Surgery, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, NY, USA
    Otolaryngol Head Neck Surg 133:936-43. 2005
    ..To determine the outcome of endoscopic repair of cerebrospinal fluid (CSF) rhinorrhea with and without computer assisted surgery...
  37. ncbi Subcranial transnasal repair of cerebrospinal fluid rhinorrhea with free autologous grafts by the combined overlay and underlay techniques
    O A El-Banhawy
    Department of ENT, Faculty of Medicine, El Menoufyia University, El Menoufyia, Egypt oelbanhawy hotmail com
    Minim Invasive Neurosurg 47:197-202. 2004
    To determine the efficacy of subcranial transnasal repair of cerebrospinal fluid rhinorrhea with free autologous grafts by the combined overlay and underlay techniques using the surgical microscope and/or endoscope.
  38. ncbi [Endoscopic treatment of cerebral rhinorrhea]
    Paweł Strek
    Katedra i Klinika Otolaryngologii Collegium Medicum UJ w Krakowie
    Otolaryngol Pol 61:69-73. 2007
    The frequency of different factors causing cerebrospinal fluid rhinorrhea (CFR) has lately changed...
  39. ncbi Clinical and radiologic sequelae of the middle fossa approach to the internal auditory canal
    Tobias Stripf
    Ear, Nose, and Throat Department, University Mainz Medical School, Mainz, Germany
    Otol Neurotol 25:787-90. 2004
    ..A grading system for computed tomography (CT) changes was developed...
  40. ncbi Endonasal endoscopic repair of cerebrospinal fluid rhinorrhea
    J A Landeiro
    Department of Neurosurgery, Brazilian Air Force Hospital, Rio de Janeiro, Brazil
    Minim Invasive Neurosurg 47:173-7. 2004
    ..The repair of the CSF rhinorrhea by endonasal endoscopic surgery is safe, very effective and is a valid alternative to the cranial approach...
  41. ncbi The endoscopic extended transsphenoidal approach for craniopharyngiomas
    Giorgio Frank
    Center of Surgery for Pituitary Tumours, Department of Neuroscience, Bellaria Hospital, Bologna, Italy
    Neurosurgery 59:ONS75-83; discussion ONS75-83. 2006
    ..The authors present their experience with this technique in 10 patients with craniopharyngiomas...
  42. ncbi Reconstruction of skull base defects after minimally invasive endoscopic resection of anterior skull base neoplasms
    Jern Lin Leong
    Department of Otolaryngology, Singapore General Hospital, Singapore
    Am J Rhinol 20:476-82. 2006
    ..The objective of this study is to describe techniques for the management of skull base defects after MIER...
  43. ncbi A novel reconstructive technique after endoscopic expanded endonasal approaches: vascular pedicle nasoseptal flap
    Gustavo Hadad
    Department of Otolaryngology Head and Neck Surgery, Medical School of Ciudad de Rosario, Provincia de Santa Fe, Republica Argentina
    Laryngoscope 116:1882-6. 2006
    ..Reconstruction with vascularized tissue is desirable to facilitate rapid healing, especially in irradiated patients...
  44. ncbi [The use of TachoComb for the rhinorrhea repair in pituitary transsphenoidal surgery]
    Ryszard Czepko
    Klinika Neurochirurgii Collegium Medium UJ w Krakowie
    Polim Med 36:3-9. 2006
    ..This complication might be serious if occurs again in the postoperative period. The aim of this study is to evaluate the sella reconstruction methods in patients with intraoperative rhinorrhea and comparing of their efficiency...
  45. ncbi Endoscopic transnasal intradural repair of anterior skull base cerebrospinal fluid fistulae
    R J S Briggs
    Department of Surgery, Royal Melbourne Hospital, Melbourne, Vic, Australia
    J Clin Neurosci 11:597-9. 2004
    ..This study presents the techniques and results of endoscopic diagnosis and repair of cerebrospinal fluid (CSF) fistulae involving the anterior skull base and paranasal sinuses...
  46. ncbi Use of a hypodense sodium fluorescein solution for the endoscopic repair of rhinogenic cerebrospinal fluid fistulae
    Ricardo Cassiano Demarco
    Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, Faculty of Medicine of Ribeirao Preto, Ribeirao Preto, Brazil
    Am J Rhinol 21:184-6. 2007
    ..Hypodense fluorescein solution can be used intrathecally to facilitate and accelerate the identification of the fistulous site...
  47. ncbi Endoscopic transnasal transethmosphenoidal approach for pituitary tumors: assessment of technique and postoperative findings of nasal and paranasal cavities
    Shinichi Haruna
    Department of Otolaryngology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu machi, Tochigi 321 0293, Japan
    Auris Nasus Larynx 34:57-63. 2007
    ..This study evaluated the transnasal transethmosphenoidal approach (TTES) in terms of its operative manipulability and the postoperative status of the paranasal cavities...
  48. ncbi Endonasal endoscopic repair of anterior skull-base fistulas: the Kuala Lumpur experience
    B S Gendeh
    Department of Otorhinolaryngology Head and Neck Surgery, Faculty of Medicine, The National University Hospital Malaysia, Kuala Lumpur, Malaysia
    J Laryngol Otol 119:866-74. 2005
    ..Therefore it is our preferred option, but an alternative procedure should be utilized should this prove necessary...
  49. ncbi [Non-traumatic cerebrospinal fluid rhinorrhea of sphenoid origin]
    P Bonfils
    Service d ORL et de Chirurgie Cervico faciale, Hopital Europeen Georges Pompidou, Faculté de Médecine de l Université Paris V, 20, rue Leblanc, 75015 Paris
    Neurochirurgie 51:193-6. 2005
    ..Presented here is a case of CSF rhinorrhea of this nature, including the diagnosis workup and endoscopic approach permitting closure of the fistula...
  50. ncbi Adult intranasal meningoencephalocele presenting as a nasal polyp
    K Krishna Kumar
    Department of Otorhinolaryngology, Sundaram Medical Foundation, Chennai, India
    J Clin Neurosci 12:594-6. 2005
    ..Based on a review of the literature, we emphasize that nasal obstruction may be the only presenting symptom of an intranasal meningoencephalocele...
  51. ncbi Endoscopic repair of CSF rhinorrhea: experience of 44 cases
    Bernardo Cunha Araujo Filho
    Division of Clinical Otorhinolaryngology, HCFMUSP
    Braz J Otorhinolaryngol 71:472-6. 2005
    ..CSF rhinorrhea is a known potential complication with significant morbidity and mortality. It may present a significant challenge in diagnosis, localization and management...
  52. ncbi Radial forearm free tissue transfer in the management of persistent cerebrospinal fluid leaks
    Stephen M Weber
    Department of Otolaryngology and Head and Neck Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    Laryngoscope 115:968-72. 2005
    ..Although numerous repair methods have been successful, the occasional patient develops a persistent leak. We describe our experience with free tissue transfer for repair of recalcitrant CSF leaks...
  53. ncbi Cranial base fracture and rhino cerebrospinmal fluid leakage. A case report
    G Magliulo
    ENT Department G Ferreri, La Sapienza University, Rome IT taly
    An Otorrinolaringol Ibero Am 34:35-44. 2007
    ..Fistulas in the ethmoid are the most difficult to diagnose and the easiest to underestimate. It is fundamental to follow the appropriate diagnostic procedure...
  54. ncbi Management of cerebral vascular structures during endoscopic treatment of encephaloceles: a clinical report
    William E Bolger
    Department of Surgery, Division of Otolaryngology, Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA
    Ann Otol Rhinol Laryngol 115:167-70. 2006
    ..With its more widespread and frequent use, unusual cases and potential complications are becoming more apparent...
  55. ncbi Spontaneous bilateral intrasphenoidal lateral encephaloceles: CT and MRI findings
    Ahmet Kemal Firat
    Department of Radiology, The University of Texas Southwestern Medical Center at Dallas, USA
    Ear Nose Throat J 83:831-3. 2004
    ..We discuss our clinical findings and the results of preoperative computed tomography and magnetic resonance imaging...
  56. ncbi Pediatric meningoencephaloceles and nasal obstruction: a case for endoscopic repair
    Seth J Kanowitz
    Head and Neck Institute, Section of Nasal and Sinus Disorders, Cleveland Clinic, Cleveland, OH, United States
    Int J Pediatr Otorhinolaryngol 70:2087-92. 2006
    ..However, owing to the rarity of these lesions, there is a paucity of data demonstrating successful adaptation of endoscopic skull base techniques to the pediatric population...
  57. ncbi Delayed absence seizure: a complication of intrathecal fluorescein injection. A case report and literature review
    Shahram Anari
    Department of Otorhinolaryngology, The Freeman University Hospital, Newcastle upon Tyne, UK
    Auris Nasus Larynx 34:515-8. 2007
    ..We also review the articles in the diagnostic methods for the CSF rhinorrhoea and the complications of the intrathecal fluorescein injection...
  58. ncbi Evolutions in the management of congenital intranasal skull base defects
    Bradford A Woodworth
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, USA
    Arch Otolaryngol Head Neck Surg 130:1283-8. 2004
    ..Congenital skull base defects have traditionally been treated via an intracranial approach. Recent advances in endoscopic management have made minimally invasive extracranial approaches feasible, with less morbidity...
  59. ncbi [Surgery at the skull base with transnasal endoscopic control]
    Gregor Bachmann-Harildstad
    Øre nese halsavdelingen, Universitetssykehuset Nord Norge, 9038 Tromsø
    Tidsskr Nor Laegeforen 128:1958-60. 2008
    ..Patients do not have visible scars and have less postoperative pain after endoscopic surgery and a decreased postoperative morbidity in general results in a shorter hospital stay...
  60. ncbi Endoscopic endonasal treatment of a spontaneous temporosphenoidal encephalocele with a detachable silicone balloon. Case report
    Alessandra Alfieri
    Department of Neurosurgery, A Manzoni Hospital, Lecco, Italy
    J Neurosurg 97:1212-6. 2002
    ..This appears to be the first case reported in the literature of a temporosphenoidal encephalocele successfully treated by an endoscopic endonasal technique involving packing of the defect with inflated detachable balloons...
  61. ncbi Endoscopic management of cerebrospinal fluid leaks
    Valerie J Lund
    Institute of Laryngology and Otology, University College London, United Kingdom
    Am J Rhinol 16:17-23. 2002
    ..Therefore, it is our preferred option, although surgeons must be prepared for alternative procedures should these prove necessary...
  62. ncbi Sellar repair in endoscopic endonasal transsphenoidal surgery: results of 170 cases
    Paolo Cappabianca
    Department of Neurological Sciences, Division of Neurosurgery, Federico II University, Naples, Italy
    Neurosurgery 51:1365-71; discussion 1371-2. 2002
    ..To describe techniques and materials used in sellar repair after an endoscopic endonasal transsphenoidal approach...
  63. ncbi Management of skull base defect with bFGF after extensive skull base surgery - two case reports
    N Hashimoto
    Department of Neurosurgery, Osaka University Graduate School of Medicine, Yamada oka, Suita, Japan
    Minim Invasive Neurosurg 51:136-9. 2008
    ..The role and safeness of bFGF for skull base reconstruction are discussed...
  64. ncbi Pituitary surgery: transsphenoidal approach
    John A Jane
    Department of Neurosurgery, University of Virginia, Charlottesville, USA
    Neurosurgery 51:435-42; discussion 442-4. 2002
    ..The methods and preferences described herein embody the distillation of an experience gained from 3900 transsphenoidal operations...
  65. ncbi Skull base cerebrospinal fluid fistulas: a comprehensive diagnostic algorithm
    Jeffrey S Zapalac
    Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas 75390, USA
    Otolaryngol Head Neck Surg 126:669-76. 2002
    ..Our goal was to assess the efficacy of current diagnostic modalities in the management of skull base cerebrospinal fluid (CSF) fistulas...
  66. ncbi Intracranial complications before and after endoscopic skull base reconstruction
    Richard J Harvey
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Am J Rhinol 22:516-21. 2008
    ..The risk of developing complications, such as meningitis, in a skull base defect is unknown. Many ESBR are multilayered soft tissue repairs, and long-term prevention of ICCs is not well described...
  67. ncbi [Spontaneous defects of the lateral cranial base. 1. Clinical aspects, diagnosis and therapy]
    J P Windfuhr
    Klinik für HNO Krankheiten, Kopf, Hals und Plastische Gesichtschirurgie, Malteser Krankenhaus St Anna, Albertus Magnus Strasse 33, 47259 Duisburg
    HNO 50:433-40. 2002
    ..The purpose of this paper is to review the literature and to present two additional case reports with emphasis on diagnostic problems and surgical techniques...
  68. ncbi Endonasal endoscopic repair of Sternberg's canal cerebrospinal fluid leaks
    Paolo Castelnuovo
    Department of Otorhinolaryngology, University of Insubria, Varese, Azienda Ospedaliero Universitaria Ospedale di Circolo e Fondazione Macchi, Varese, Italy
    Laryngoscope 117:345-9. 2007
    ..The aim of the study was to assess the real effectiveness of an endoscopic endonasal approach for treating cerebrospinal fluid leaks of the lateral recess of the sphenoid sinus...
  69. ncbi Preoperative disease severity at sites of subsequent skull base defects after endoscopic sinus surgery
    John M DelGaudio
    Department of Otolaryngology Head and Neck Surgery, Emory University School of Medicine, Atlanta, Georgia, USA
    Am J Rhinol 22:321-4. 2008
    ..We evaluated preoperative computed tomography (CT) scans to determine the degree of mucosal disease present at the site of subsequent SB defects caused by ESS...
  70. doi Acute hydrocephalus after endoscopic repair of cerebrospinal fluid rhinorrhea
    Chia Chen Wu
    Department of Otolaryngology, Chang Gung Memorial Hospital, 5 Fu Shin Street, Kwei Shan, Taoyuan, Taiwan
    Otolaryngol Head Neck Surg 139:602-3. 2008
  71. ncbi [Value of endonasal endoscopic surgery in the treatment of sphenoid cerebrospinal rhinorrheas. 15 cases]
    N Guevara
    , Service d'ORL et de chirurgie de la face et du cou, 30 avenue de la voie romaine BP 69, 06002 Nice, France
    Rev Laryngol Otol Rhinol (Bord) 122:5-11. 2001
    ..Endonasal surgery under optic guidance compared to the transrhinoseptal approach represents an attractive alternative with less undesirable iatrogenic consequences...
  72. ncbi Management of sphenoid sinus cerebrospinal fluid rhinorrhea: making use of an extended approach to the sphenoid sinus
    Neelesh H Mehendale
    Department of Otolaryngology Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas 75390 9035, USA
    Otolaryngol Head Neck Surg 126:147-53. 2002
    ..The objective of this study was to review the cause and management of CSF rhinorrhea arising from the sphenoid sinus...
  73. ncbi Passive marker computer-aided sinonasal and cranial base surgery: observations from a learning curve
    Christopher H Rassekh
    Department of Otolaryngology, West Virginia University School of Medicine, PO Box 9200, Morgantown, West Virginia 26506 9200, USA
    Ann Otol Rhinol Laryngol 112:45-51. 2003
    ..tumors (n = 9), fungal sinusitis (n = 4), recurrent polyps (n = 3), chronic sinusitis (n = 3), and cerebrospinal fluid rhinorrhea (n = 2). Passive marker computer-aided surgery was successful in 19 of the 21 patients...
  74. ncbi [Endoscopic reconstruction of the anterior skull base in cerebrospinal rhinorrhea]
    Wojciech Golusinski
    Katedra i Klinika Otolaryngologii AM im Karola Marcinkowskiego w Poznaniu
    Otolaryngol Pol 57:75-9. 2003
    ....
  75. ncbi Overlapping free bone graft with galea-pericranium in reconstruction of the anterior skull base to prevent CSF leak and sequestrum formation
    T Abe
    Department of Neurosurgery, Oita University School of Medicine, Idaigaoka, Hasama, Yufu, Oita, Japan
    Acta Neurochir (Wien) 149:771-5; discussion 775. 2007
    ..Conclusion. Three dimensional computed tomography (3D-CT) at bone window settings demonstrated the bone graft covered the bone defect and was not absorbed and after 11 years there have been no signs of tumour regrowth or complications...
  76. ncbi Congenital transsphenoidal meningocele: case report and review of the literature
    Catherine Blaivie
    Department of Otorhinolaryngology, Head and Neck Surgery, CHU Saint Pierre, Brussels, Belgium
    Am J Otolaryngol 27:422-4. 2006
    ..We report a case of sphenoidal meningocele treated using an endoscopic procedure and review the literature regarding its congenital origin...
  77. ncbi [A case report of sphenoidal encephalocele presenting with cerebral spinal fluid rhinorrhea]
    Masaru Takeda
    Department of Neorosurgery, Iwate Medical University, 19 1 Uchimaru, Morioka City, Iwate 020 8505, Japan
    No Shinkei Geka 32:37-41. 2004
    ..We diagnosed the lesion as sphenoidal encephalocele. Surgical repair and amputation of the encaphalocele was performed. Sphenoidal encaphalocele should be considered as a possible diagnosis for recurrent fever and rhinorrhea...
  78. ncbi Endoscopic repair of large skull base defects after powered sinus surgery
    Christopher A Church
    Stanford Sinus Center, Division of Otolaryngology, Stanford University School of Medicine, Stanford, California 94305, USA
    Otolaryngol Head Neck Surg 129:204-9. 2003
    ..Study design and setting All patients treated for postendoscopic sinus surgery skull base injury over a 4-year period were reviewed...
  79. ncbi Mid-term rhinosinusal consequences of bony orbital decompression in Graves' disease: a retrospective study
    T Maalouf
    Oculoplastic Department, Ophtalmologie B, CHU Nancy, France
    Orbit 27:169-73. 2008
    ..The aim of this work was to detect and study mid-term rhinosinusal complications arising after bony orbital decompression via the inferior palpebral approach in patients with Graves' ophthalmopathy...
  80. ncbi Cranial bone grafts in cerebrospinal fluid leak and encephalocele repair: a preliminary report
    William E Bolger
    Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    Am J Rhinol 17:153-8. 2003
    ..of endoscopic surgery, otolaryngologists are increasingly being called on to care for patients with cerebrospinal fluid rhinorrhea and meningoencephaloceles...
  81. ncbi Endoscopic endonasal resection of a midline intradural frontobasal dermoid tumour
    B Duz
    Department of Neurosurgery, Gulhane Military Medical Academy GATA, Ankara, Turkey
    Minim Invasive Neurosurg 50:363-6. 2007
    ..Reconstruction is very important after the surgery and a carefully planned pedicled graft technique may help in the prevention of cerebrospinal fluid leakage...
  82. ncbi Endoscopic endonasal surgery (EES) in skull base repairs and CSF leakage
    C Bachert
    ENT-Department Head and Neck Surgery, University Hospital Ghent, Belgium
    Acta Otorhinolaryngol Belg 54:179-89. 2000
    ..This also applies for lesions of other aetiologies. The Belgian data support the statement that the endonasal endoscopic approach is a suitable and successful technique to close CSF leaks in the vast majority of our patients...
  83. ncbi Intrasphenoidal encephalocele associated with cerebrospinal fluid fistula and subdural hematomas: technical case report
    Bernardo Fraioli
    Department of Neuroscience, Neurosurgery, University of Rome Tor Vergata, Via Montpellier 1, 00133 Rome, Italy
    Neurosurgery 52:1487-90; discussion 1490. 2003
    ..A surgical procedure to stop persistent cerebrospinal fluid leakage is reported...
  84. ncbi CSF rhinorrhoea: the place of endoscopic sinus surgery
    A H Marshall
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital, Nottingham, UK
    Br J Neurosurg 15:8-12. 2001
    ..We illustrate our experience with 78 patients who were referred with a diagnosis of CSF rhinorrhoea...
  85. ncbi Endoscopic management of sphenoid sinus cerebrospinal fluid leaks
    Nathan B Sautter
    Section of Nasal and Sinus Disorders, Head and Neck Institute, Cleveland Clinic, 9500 Euclid Ave, Desk A71, Cleveland, OH 44195, USA
    Ann Otol Rhinol Laryngol 117:32-9. 2008
    ....
  86. ncbi Utility of preoperative high-resolution CT and intraoperative image guidance in identification of cerebrospinal fluid leaks for endoscopic repair
    Jodi D Zuckerman
    Department of Otolaryngology Head and Neck Surgery, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Am J Rhinol 22:151-4. 2008
    ..This study examines endoscopic repair of CSF leaks using preoperative high-resolution CT (HRCT) and intraoperative IGS without IF or LD...
  87. ncbi Spontaneous nasal cerebrospinal fluid leaks and empty sella syndrome: a clinical association
    Rodney J Schlosser
    Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    Am J Rhinol 17:91-6. 2003
    ..The objective of this study was to examine the association between spontaneous encephaloceles/CSF leaks and empty sella syndrome because of their similar clinical features and potential common pathophysiology...
  88. ncbi Inadvertent intracranial insertion of a soft rubber tube in a patient with Treacher-Collins syndrome: case report and review of literature
    Dattatraya Muzumdar
    Division of Neurosurgery, Children s Hospital of Eastern Ontario, 401 Smyth Road, Ottawa, ON, Canada, K1H 8 L1
    Childs Nerv Syst 24:609-13. 2008
    ..The patient developed bacterial meningitis, communicating hydrocephalus followed by cerebrospinal fluid rhinorrhea. A transcranial repair of the anterior cranial fossa was performed followed by ventriculoperitoneal ..
  89. pmc Refractory cerebrospinal fluid rhinorrhea secondary to occult superior vena cava syndrome and benign intracranial hypertension: diagnosis and management
    Jonathan M Bledsoe
    Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota
    Skull Base 19:279-85. 2009
    ..If endoscopic transnasal repair fails, craniotomy and direct suture repair and autologous tissue reinforcement of the skull base may prove successful and durable, even if BIH persists...
  90. ncbi Management of petrous endostosis in posterior fossa procedures for trigeminal neuralgia
    Emad F Shenouda
    Department of Neurosurgery, Frenchay Hospital, Bristol, England
    Neurosurgery 60:ONS63-9; discussion ONS69. 2007
    ..The surgical management and clinical outcomes of these patients are presented...
  91. ncbi How to make the blockage between the nasal cavity and intracranial space using a four-layer sealing technique
    Yoonho Lee
    Department of Plastic and Reconstructive Surgery, College of Medicine, Seoul National University, Seoul, South Korea
    Plast Reconstr Surg 117:233-8. 2006
    ....
  92. ncbi Prophylactic administration of ceftriaxone for the prevention of meningitis after traumatic pneumocephalus: results of a clinical trial
    Behzad Eftekhar
    Department of Neurosurgery, Sina Hospital, Tehran University, Iran
    J Neurosurg 101:757-61. 2004
    ..The purpose of this study was to compare the efficacy of the prophylactic use of ceftriaxone for the prevention of meningitis in patients with acute traumatic pneumocephalus...
  93. ncbi [Early outcome of one-stage transnasal surgery combined with transnasal surgery for cranionasal tumors and reconstruction of skull base]
    Bowen Cai
    Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu Sichuan, 610041, P R China
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 22:589-92. 2008
    ..To investigate the microsurgical management of cranionasal tumors and the method of the reconstruction of the skull base...
  94. ncbi Long-term endonasal endoscopic review of successful duraplasty after endonasal endoscopic skull base surgery
    Omar A El-Banhawy
    Department of ENT Surgery, El Menoufyia University, El Menoufyia, Egypt
    Am J Rhinol 22:175-81. 2008
    ..This study was performed to examine the long-term endonasal endoscopic morphological appearance of successful duraplasty after endoscopic skull base surgery for different pathology...
  95. ncbi Assessing cerebrospinal fluid rhinorrhea: a two-dimensional electrophoresis approach
    P R Burkhard
    Department of Neurology, University Hospital, Geneva, Switzerland
    Electrophoresis 22:1826-33. 2001
    ..These preliminary results suggest that a 2-DE-based multimarker approach is a valid, sensitive, and specific method to assess the presence of CSF in occult rhinorrhea...
  96. ncbi Salvage optic nerve decompression for traumatic blindness under nasal endoscopy: risk and benefit analysis
    H B Li
    Department of Otolaryngology, First Affiliated Hospital of Nanjing Medical University, Nanjing, China
    Clin Otolaryngol 32:447-51. 2007
    ..The aim of this study was to assess the risks and benefits of salvage surgical decompression for complete vision loss (no light detection) after failure of mega-dose steroid therapy...
  97. ncbi Middle fossa approach to a temporosphenoidal encephalocele -technical note-
    Jae Eun Kwon
    Division of Skull Base Surgery, Department of Neurosurgery, Dongsan Medical Center, Keimyung University School of Medicine, Jung Gu, Daegu, Republic of Korea
    Neurol Med Chir (Tokyo) 50:434-8. 2010
    ..A 45-year-old woman presented with a spontaneous TSE manifesting as a 4-year history of recurrent cerebrospinal fluid rhinorrhea and meningitis...
  98. ncbi Vestibular schwannoma surgery outcomes: our multidisciplinary experience in 400 cases over 17 years
    Vincent Darrouzet
    Department of Skull Base Surgery, University Hospital of Bordeaux, Bordeaux, France
    Laryngoscope 114:681-8. 2004
    ..The aim of the study was to evaluate the incidence of short- and intermediate-term postoperative complications after vestibular schwannoma surgery...
  99. ncbi Massive pneumocephalus following Merocel nasal tamponade for epistaxis
    G J Hollis
    Department of Emergency Medicine, St George Hospital, Sydney, Australia
    Acad Emerg Med 7:1073-4. 2000
    ..An 89-year-old patient was found to have cerebrospinal fluid rhinorrhea and massive pneumocephalus immediately after removal of a Merocel tampon used for spontaneous anterior ..
  100. ncbi Spinal arachnoid cyst causing paraplegia following skull base surgery
    Ryu Kurokawa
    Department of Neurological Surgery, Dokkyo University School of Medicine, Tochigi, Japan
    Neurol Med Chir (Tokyo) 46:309-12. 2006
    ..The postoperative course was complicated by cerebrospinal fluid rhinorrhea, bacterial meningitis, and acute hemorrhagic rectal ulcer...
  101. ncbi Detection of spontaneous cerebrospinal fluid rhinorrhea
    Otakar Kraft
    Department of Nuclear Medicine, University Hospital, 17 listopadu 1790, 708 52 Ostrava Poruba, Chech Republic
    Hell J Nucl Med 7:56-7. 2004
    ..RS) is a highly sensitive, reliable and safe technique used for the confirmation of the presence of cerebrospinal fluid rhinorrhea and the localisation of fistula...

Research Grants4

  1. A HEMODYNAMIC MODEL OF INTRACRANIAL PRESSURE DYNAMICS
    Marvin Bergsneider; Fiscal Year: 2002
    ..An improved understanding of these disorders will offer new and better treatment modalities for millions of affected patients. ..
  2. In Vivo Imaging of Post-Traumatic Cerebral Amyloid Deposition
    Marvin Bergsneider; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  3. In Vivo CSF Shunt Hydrodynamics in Hydrocephalus
    Marvin Bergsneider; Fiscal Year: 2010
    ..Documenting definitive evidence of the tuned-dynamic absorber model could have fundamental implications to all ICP disorders. ..
  4. Hypopituitarism after Moderate and Severe Head Injury
    Daniel Kelly; Fiscal Year: 2008
    ..By diagnosing and treating both acute and chronic traumatic neuroendocrine deficiencies, this study may dramatically improvethe long-term prognosis of many TBI patients. ..