Genomes and Genes
closed head injuries
Summary: Traumatic injuries to the cranium where the integrity of the skull is not compromised and no bone fragments or other objects penetrate the skull and dura mater. This frequently results in mechanical injury being transmitted to intracranial structures which may produce traumatic brain injuries, hemorrhage, or cranial nerve injury. (From Rowland, Merritt's Textbook of Neurology, 9th ed, p417)
Publications236 found, 100 shown here
- The use of clinical CCT images in the forensic examination of closed head injuriesM Bauer
Institute of Legal Medicine, University of Wuerzburg, Versbacher Strasse 3, 97078 Wuerzburg, Germany
J Clin Forensic Med 11:65-70. 2004..To have unbiased access to these information, it is useful to evaluate the CT scans personally which requires a basic knowledge of traumatic changes found on radiographs...
- Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injuryIdo Yatsiv
Pediatric Intensive Care Unit and Department of Pharmacology, Hebrew University Hadassah Medical Center, Jerusalem, Israel
J Cereb Blood Flow Metab 22:971-8. 2002..However, brain edema at 24 hours was not influenced by IL-18BP, suggesting that inflammatory mediators other than IL-18 induce the early detrimental effects of intracerebral inflammation...
- Erythropoietin is neuroprotective, improves functional recovery, and reduces neuronal apoptosis and inflammation in a rodent model of experimental closed head injuryI Yatsiv
Department of Pharmacology, School of Pharmacy, Hebrew University Hadassah Medical Center, Jerusalem, Israel
FASEB J 19:1701-3. 2005..vehicle-treated animals. We propose that further studies on Epo in TBI should be conducted in order to consider it as a novel therapy for TBI...
- Determinants of mortality in patients with severe blunt head injuryMartin A Schreiber
Department of Surgery, Baylor College of Medicine, Houston, TX, USA
Arch Surg 137:285-90. 2002..Head injury is the leading cause of traumatic death in the United States...
- Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokinesP F Stahel
Department of Surgery, University Hospital, Zurich, Switzerland
J Cereb Blood Flow Metab 20:369-80. 2000..Nevertheless, the increased posttraumatic mortality in TNF/LT-alpha-deficient mice suggests a protective effect of these cytokines by mechanisms that have not been elucidated yet...
- Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic miceMario Rancan
Department of Trauma Surgery, The Alfred Hospital and Monash University, Melbourne, Victoria, Australia
J Cereb Blood Flow Metab 23:1070-4. 2003..This work further implicates the complement system as a participant in secondary progression of brain damage after head trauma and provides a strong rationale for future studies of posttraumatic pharmacologic complement inhibition...
- The benefit of routine thoracic, abdominal, and pelvic computed tomography to evaluate trauma patients with closed head injuriesMichael L Self
Department of Surgery, Methodist Hospitals of Dallas, Dallas, TX, USA
Am J Surg 186:609-13; discussion 613-4. 2003..We sought to evaluate the role of routine computed tomography (CT) of the chest, abdomen, and pelvis as a screening tool for patients already undergoing cranial CT studies...
- Intracerebral complement C5a receptor (CD88) expression is regulated by TNF and lymphotoxin-alpha following closed head injury in miceP F Stahel
Department of Surgery, Division of Trauma Surgery and Division of Research, University Hospital, CH 8091, Zurich, Switzerland
J Neuroimmunol 109:164-72. 2000..These data show that the posttraumatic neuronal expression of the C5aR is, at least in part, regulated by TNF and lymphotoxin-alpha at 7 days after trauma...
- Finite element modelling of human head injuries caused by a fallJean Sebastien Raul
Institut de Medecine Legale, 11 rue Humann, 67085 Strasbourg, France
Int J Legal Med 120:212-8. 2006..We show that this tool can be used to discuss the possible mechanism of injury encountered for the observed lesions in a forensic case. It can also help to distinguish between possible and impossible human head injury mechanisms...
- Hemostatic abnormalities in patients with closed head injuries and their role in predicting early mortalityVineet Saggar
Department of Neurosurgery, S M S Medical College, Jaipur, India
J Neurotrauma 26:1665-8. 2009..From this study we conclude that hemostatic abnormalities are independent predictors of early mortality in moderate-to-severe head injury patients...
- CT and MR imaging of acute cranial traumaJames Provenzale
Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA
Emerg Radiol 14:1-12. 2007....
- Closed head injury--an inflammatory disease?Oliver I Schmidt
Department of Trauma and Reconstructive Surgery, Charité University Medical School Berlin, Campus Benjamin Franklin, Germany
Brain Res Brain Res Rev 48:388-99. 2005....
- Automating 3D meshing method for patient-specific modelingYabo Guan
Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA
Biomed Sci Instrum 42:199-204. 2006..Both static and dynamic analyses were performed to verify the models. The study for blunt impact of infant head was performed by using these patient-specific models...
- Early predictors of mortality and morbidity after severe closed head injuryE Lannoo
Department of Neuropsychology and Rehabilitation, University Hospital, Gent, Belgium
J Neurotrauma 17:403-14. 2000..Those factors important for predicting mortality (clinical variables such as ICP or blood glucose level, and CT observations) failed to show any significant relationship with morbidity...
- Effects of head posture on cerebral hemodynamics: its influences on intracranial pressure, cerebral perfusion pressure, and cerebral oxygenationIvan Ng
Department of Neurosurgery, National Neuroscience Institute, and Faculty of Medicine, National University of Singapore, Singapore
Neurosurgery 54:593-7; discussion 598. 2004..We sought to determine the impact of supine and 30 degrees semirecumbent postures on cerebrovascular dynamics and global as well as regional cerebral oxygenation within 24 hours of trauma...
- Routine evaluation of the cervical spine in head-injured patients with dynamic fluoroscopy: a reappraisalJ W Davis
Division of Neurosurgery, Department of Surgery, University Medical Center, UCSF/Fresno, 445 South Cedar Ave, Fresno, CA 93702, USA
J Trauma 50:1044-7. 2001..If dynamic fluoroscopy is to be used, adherence to the protocol, including review of the cervical spine radiographs before fluoroscopy and visualization of the entire cervical spine, C1-T1, is mandatory to ensure patient safety...
- Intermittent burst-firing weak (1 microTesla) magnetic fields reduce psychometric depression in patients who sustained closed head injuries: a replication and electroencephalographic validationLaura Baker-Price
Laurentian University, Sudbury, ON Canada
Percept Mot Skills 96:965-74. 200314 patients who reported chronic depression more than one year after closed head injuries were exposed to weak (1 microTesla), burst-firing magnetic fields either across the temporal lobes or over the left frontal lobe...
- Comparison of intracranial pressure measured in the cerebral cortex and the cerebellum of the ratServan Rooker
Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, B 2650 Edegem, Antwerp, Belgium
J Neurosci Methods 119:83-8. 2002..We conclude that in rats the ICP measurement in the cerebellum is comparable to the ICP measurement in the cerebral cortex. The cerebellar ICP can be used as a valuable alternative during experimental procedures...
- Basic science of closed head injuries and spinal cord injuriesDavid O Okonkwo
Department of Neuroscience, University of Virginia, PO Box 800212, Charlottesville, VA 22908 0212, USA
Clin Sports Med 22:467-81. 2003..As no panacea exists, improvements in experimental models have empowered researchers in their search for novel therapeutic strategies...
- Do children require hospitalization after immediate posttraumatic seizures?James F Holmes
Division of Emergency Medicine, Department of Internal Medicine, University of California Davis, School of Medicine, Sacramento, CA, USA
Ann Emerg Med 43:706-10. 2004..We determine whether children with immediate posttraumatic seizures require hospitalization for observation of possible neurologic complications...
- Ocular manifestations of head injury: a clinical studyA R Kulkarni
1Department of Ophthalmology, The Guest Hospital, Dudley Group of Hospitals NHS Trust, West Midlands, UK
Eye (Lond) 19:1257-63. 2005..This prospective study aimed to clinically correlate the various ocular findings with the neurological status in cases of closed head injury...
- Waiting for the patient to "sober up": Effect of alcohol intoxication on glasgow coma scale score of brain injured patientsJason L Sperry
Division of Burns, Trauma and Surgical Critical Care, Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas 75390 9158, USA
J Trauma 61:1305-11. 2006..Alcohol intoxication may limit the ability of the Glasgow Coma Scale (GCS) to accurately assess severity of TBI. We hypothesized that alcohol intoxication significantly depresses GCS scores of TBI patients...
- Neuroplasticity following non-penetrating traumatic brain injuryHarvey S Levin
Cognitive Neuroscience Laboratory, Baylor College of Medicine, Houston, TX 77030, USA
Brain Inj 17:665-74. 2003..Functional MRI, coupled with DTI and possibly other imaging modalities holds the promise of elucidating mechanisms of neuroplasticity and repair following TBI...
- Olfactory dysfunction: a sequela of pediatric blunt head traumaAmanda A Sandford
San Diego State University, Center for Lifespan Human Senses, Department of Psychology, 6363 Alvarado Court, Ste 101, San Diego, CA 92120 4913, USA
Int J Pediatr Otorhinolaryngol 70:1015-25. 2006..To evaluate olfactory function in children with blunt head trauma...
- [Recent findings in minor traumatic brain injury in sports]N Biasca
Leiter Orthopädie und Sportmedizin, Leitender Arzt Traumatologie, Medical Consultant of the International Ice Hockey Federation IIHF, Spital Oberengadin, 7503 Samedan, Schweiz
Zentralbl Chir 131:506-8. 2006
- [Diagnosis and management of patients with mild traumatic brain injury--an update with recommendations and future perspectives]O P Gautschi
Department of Orthopaedic Surgery, Royal Perth Hospital, University of Western Australia, Perth
Praxis (Bern 1994) 96:53-8; discussion 59-60. 2007..Notably, the conventional X-ray is inadequate for the assessment of TBI. The following article discusses practical algorithms for the management of mild TBI and the indications for early use of CT...
- CT for acute stage of closed head injuryYoshihiro Toyama
Department of Clinical Radiology, Faculty of Medicine, Kagawa University, Japan
Radiat Med 23:309-16. 2005..In this article, we review the imaging findings and literature of various lesions of closed head injury in the acute stage...
- Predictors of intracranial injuries in children after blunt head traumaLiviana Da Dalt
Dipartimento di Pediatria, Universita di Padova, Via Giustiniani 3, 35128, Padova, Italy
Eur J Pediatr 165:142-8. 2006..The five-group classification of children allowed an excellent prediction in terms of likelihood of ICI (ROC area 0.972)...
- Traumatic interhemispheric subdural hematomaYong xu Piao
Department of Neurosurgery, Chengdu Military General Hospital, Chengdu 610083, China
Chin J Traumatol 6:186-9. 2003
- Blunt cervical spine injuries in Scotland 1995-2000Elaine K Drainer
Department of Accident and Emergency Medicine, Southern General Hospital, 1345 Govan Road, Glasgow G51 4TF, UK
Injury 34:330-3. 2003..This study aimed to evaluate the incidence of CSI in patients sustaining blunt head injuries in a Scottish population...
- Loss of consciousness and/or amnesia after blunt head trauma in childrenNathan Kuppermann
Pediatr Crit Care Med 6:93-4. 2005
- Necessity of hospital admission for pediatric minor head injuryMatthew T Spencer
Department of Emergency Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
Am J Emerg Med 21:111-4. 2003..We conclude that pediatric patients with MHI and negative CT scans of the head do not require routine admission for observation for delayed complications...
- Diagnosis and management of pediatric closed head injurySami Khoshyomn
Division of Neurosurgery, University of Vermont, 111 Colchester Avenue, Fletcher 5, Burlington, VT 05401, USA
Semin Pediatr Surg 13:80-6. 2004..In this article, early diagnosis and initial management of the most common forms of pediatric closed head injury are reviewed...
- Controversies in the evaluation and management of minor blunt head trauma in childrenDavid Schnadower
Division of Pediatric Emergency Medicine, Morgan Stanley Children s Hospital of New York Presbyterian, Columbia University College of Physicians and Surgeons, 622 West 168th Street, New York, NY 10032, USA
Curr Opin Pediatr 19:258-64. 2007..We present data from recently conducted research regarding controversial aspects of the evaluation and management of children with minor blunt head trauma...
- Indications for routine repeat head computed tomography (CT) stratified by severity of traumatic brain injuryCarlos V R Brown
Department of Surgery, Division of Trauma and Critical Care, Los Angeles County and University of Southern California Medical Center, Los Angeles, California, USA
J Trauma 62:1339-44; discussion 1344-5. 2007..The specific aim of this study is to identify patients with head injuries who would benefit from a routine repeat head CT...
- Isolated oculomotor palsy following minor head traumaRichard L Levy
Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD, USA
Neurology 65:169. 2005
- The "CT comma sign" in head trauma: concurrent epidural and subdural acute intracranial hematomasGuillermo A Monsalve
Department of Neurosurgery, Hospital Militar Central, Bogota, Colombia
J Trauma 63:195-6. 2007
- Injuries from motorcycle- and moped crashes in Sweden from 1987 to 1999Magnus Aare
Department of Aeronautics, Royal Institute of Technology, 10044 Stockholm, Sweden
Inj Control Saf Promot 10:131-8. 2003..Concussion was the most frequent head injury. Focal and diffuse brain injuries combined showed the same frequency as concussion. It is concluded that more preventative strategies must be presented before the injury rate can be reduced...
- The effect of fresh frozen plasma in severe closed head injuryHamid Etemadrezaie
Neurosurgical Department, Shahid Kamyab Emdadi Hospital, Mashhad University of Medical Sciences MUMS, Mashhad, Iran
Clin Neurol Neurosurg 109:166-71. 2007..In this study we evaluated the effect of fresh frozen plasma (FFP) on the reduction in the incidence of DTICH in severe closed head injury victims...
- Understanding predictors of functional recovery and outcome 30 months following early childhood head injuryVicki A Anderson
Department of Psychology, University of Melbourne, Royal Children s Hospital, Melbourne, Vic, Australia
Neuropsychology 20:42-57. 2006..In conclusion, children with more severe injuries and lower preinjury adaptive abilities, and whose families are coping poorly, are at greatest risk of long-term impairment in day-to-day skills, even several years postinjury...
- Does an isolated history of loss of consciousness or amnesia predict brain injuries in children after blunt head trauma?Michael J Palchak
Division of Emergency Medicine, Department of Internal Medicine, University of California, Davis School of Medicine, Davis, California 95817 2282, USA
Pediatrics 113:e507-13. 2004..A history of loss of consciousness (LOC) is frequently used as an indication for cranial computed tomography (CT) in the emergency department (ED) evaluation of children with blunt head trauma...
- Reliability of clinical guidelines in the detection of patients at risk following mild head injury: results of a prospective studyJavier Ibanez
Department of Neurosurgery, Vall d Hebron University Hospital, Barcelona, Spain
J Neurosurg 100:825-34. 2004....
- Pediatric minor closed head injuryMary L Thiessen
Department of Emergency Medicine, University of Arizona, 1515 North Campbell Avenue, Tucson, AZ 85724, USA
Pediatr Clin North Am 53:1-26, v. 2006..Evidence strongly supports a lower threshold to perform a CT scan in younger children because they have a higher risk of significant brain injury after blunt head trauma...
- Loss of consciousness: when to perform computed tomography?Michelle K Halley
Children s Hospital and Health Center, San Diego, CA 92123, USA
Pediatr Crit Care Med 5:230-3. 2004....
- Epidemiology of blunt head injury victims undergoing ED cranial computed tomographic scanningJames F Holmes
Department of Emergency Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA
Am J Emerg Med 24:167-73. 2006..We sought to describe the epidemiology of emergency department (ED) patients with blunt head injury undergoing cranial computed tomography (CT) scanning for the evaluation of possible traumatic brain injury (TBI)...
- [Nursing children with head injuries]Monika Hinkeldey
Kinderkrankenschwester und Fachschwester fur Internsivmedizin im Kindesalter Klinik und Poliklinik fur Kinferchirurgue des Universitätsklinikums Leipzig
Kinderkrankenschwester 23:63-8. 2004
- Evaluation of mild head injury in a pediatric populationBurak O Boran
2nd Neurosurgery Clinic, Dr Lutfi Kirdar Kartal Research and Training Hospital, Istanbul, Turkey
Pediatr Neurosurg 42:203-7. 2006....
- [The undetected brain lesion in sports. Minor traumatic brain injury and its sequelae]N Biasca
Traumatologie, Orthopädie und Sportmedizin, Medical Consultant of the International Ice Hockey Federation IIHF, Spital Oberengadin, Samedan, Schweiz
Unfallchirurg 109:101-11. 2006..In the future biochemical markers may serve as indicators of the severity of the brain injury and may also aid in predicting the outcome after TBI. Today biochemical markers do not serve as a substitute for neuroimaging...
- Working memory after mild, moderate, or severe childhood closed head injuryCaroline Roncadin
Department of Psychology, Hospital for Sick Children, Toronto, Ontario, Canada
Dev Neuropsychol 25:21-36. 2004..Age at injury and time since injury predicted WM components only for the moderate group. Survivors of moderate or severe childhood CHI have persisting WM deficits limiting the computational workspace required for many cognitive tasks...
- The impact of mild developmental learning difficulties on neuropsychological recovery from head traumaRodger L L Wood
Department of Psychology, University of Wales Swansea, Swansea, Wales, UK
Brain Inj 20:477-84. 2006..To investigate the prevalence of mild developmental learning difficulties (MDLD) in a group of patients who had sustained head trauma, to determine the impact on cognitive and neurobehavioural recovery...
- Defining "therapeutically inconsequential" head computed tomographic findings in patients with blunt head traumaClare Atzema
Emergency Medicine Center, University of California Los Angeles School of Medicine, Los Angeles, CA 90024, USA
Ann Emerg Med 44:47-56. 2004..quot; We estimate the prevalence of these findings and determine how frequently affected patients had "important neurosurgical outcomes," defined as either a directed intervention or a poor Glasgow Outcome Scale score...
- Performance of a decision rule to predict need for computed tomography among children with blunt head traumaJennifer A Oman
Department of Emergency Medicine, College of Medicine, University of California, Irvine, California, USA
Pediatrics 117:e238-46. 2006..To assess the ability of the NEXUS II head trauma decision instrument to identify patients with clinically important intracranial injury (ICI) from among children with blunt head trauma...
- Large animal models of traumatic injury to the immature brainAnn Christine Duhaime
Pediatric Neurosurgery, Children s Hospital at Dartmouth, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
Dev Neurosci 28:380-7. 2006..Progress to date and future directions are outlined...
- Diffusion-weighted MR imaging in closed head injury: high correlation with initial glasgow coma scale score and score on modified Rankin scale at dischargePamela W Schaefer
Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Gray B285, Boston, MA 02114, USA
Radiology 233:58-66. 2004..To determine whether diffusion-weighted magnetic resonance (MR) imaging findings and conventional MR imaging findings correlate with initial Glasgow Coma Scale score and score on modified Rankin scale at discharge...
- Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injuryLauralyn A McIntyre
Centre for Transfusion and Critical Care Research, Clinical Epidemiology Unit, Critical Care Program, University of Ottawa and Ottawa Health Research Institute, Ottawa, Ontario
Neurocrit Care 5:4-9. 2006..To compare a restrictive versus a liberal transfusion strategy in patients with moderate to severe closed head injury following multiple trauma in 13 Canadian intensive care units (ICUs)...
- Hyperacute head injuries and the timing of computed tomographyAndreas K Demetriades
Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
J Trauma 57:925. 2004
- Indications for brain CT scan in patients with minor head injuryMasih Saboori
Department of Neurosurgery, Medical School, Medical University of Isfahan, Isfahan, Iran
Clin Neurol Neurosurg 109:399-405. 2007..The aim of this study was to find clinical signs and symptoms which help to predict the indications for brain CT scan following minor head injury...
- [Minor craniocerebral trauma]D Scharplatz
Chirurgische Abteilung, Spital Thusis
Praxis (Bern 1994) 91:1428-31. 2002..Wherever computerized tomography (CT) is available, a CT examination is broadly indicated. There is no knowledge of any adverse effects on patients whose GCS worsened when the CT revealed normal findings...
- A picture worth remembering: posttraumatic Purtscher's retinopathy in a childCharuta Joshi
Section of Pediatric Neurology, Chidren s Hospital, Winnipeg, Manitoba, Canada
J Child Neurol 23:353-5. 2008..The case of a 6-year-old girl with Purtscher's retinopathy is described, and the relevant literature is reviewed...
- Appearances are deceptive? Long-term cognitive and central auditory sequelae from closed head injuryPer Olof Bergemalm
Ahlsen Research Institute, Orebro University Hospital, Sweden
Int J Audiol 44:39-49. 2005..The cognitive tasks used in the study have proved to be a sensitive method to discover cognitive impairments. Long-term cognitive sequelae and APD could not be predicted from RLS scores...
- Effect of impact on different regions of the head of lambsJ W Finnie
Veterinary Services Division and Neuropathology Laboratory, Institute of Medical and Veterinary Science, Adelaide, South Australia 5000, Australia
J Comp Pathol 124:159-64. 2001..The findings should assist clinicians in evaluating the probable outcome of traumatic head injury in domestic animals. Copyright Harcourt Publishers Ltd...
- Damage to intracranial optic pathways in fatal closed head injury in manB Perunovic
Department of Neuropathology, Frenchay Hospital, Bristol BS161LE, UK
J Neurol Sci 185:55-62. 2001..The findings suggest that damage to the posterior parts of the optic pathways may be under-diagnosed among patients with head injury...
- Pediatric minor head trauma: indications for computed tomographic scanning revisitedB Simon
Baystate Medical Center, Springfield, Massachusetts, USA
J Trauma 51:231-7; discussion 237-8. 2001..A liberal policy of CT scanning is warranted for pediatric patients with a high-risk mechanism of injury despite maintenance of normal neurologic status in the field and at hospital screening...
- Massive subgaleal hematomaRafael de Oliveira Sillero
Department of Neurosurgery, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, Sao Paulo, Brazil
J Trauma 65:963. 2008
- Reimaging in pediatric neurotrauma: factors associated with progression of intracranial injuryAndy Givner
Department of Surgery, Walter Reed Army Hospital, Division of Neuroradiology Surgery, Boston University School of Medicine, Boston, MA, USA
J Pediatr Surg 37:381-5. 2002....
- Computed tomographic brain density measurement as a predictor of elevated intracranial pressure in blunt head traumaKenji Inaba
Division of Trauma Surgery and Surgical Critical Care, University of Southern California, Los Angeles, California 90033, USA
Am Surg 73:1023-6. 2007..6 HU) versus CPP 70 or greater (26.2, P = 0.436). CT-measured brain density does not correlate with elevated ICP or depressed CPP and cannot predict patients with traumatic brain injury who would benefit from invasive ICP monitoring...
- Selective alexia and agraphia sparing numbers-a case studyRandi Starrfelt
Department of Psychology, University of Copenhagen, Linnesgade 22, DK 1361, Copenhagen, Denmark
Brain Lang 102:52-63. 2007..We suggest that a deficit in a visuo-motor network containing knowledge of the physical shape of letters might explain the pattern of performance displayed by MT...
- Severe traumatic brain injury in children--are the results improving?Jurg Pfenninger
Pediatric Intensive Care Unit, University Children s Hospital, Inselspital, Bern, Switzerland
Swiss Med Wkly 132:116-20. 2002..Medical management is constantly being refined, and thus results should improve. The aim of the present study was to analyse our data of recent years and to compare them with previous series (1978-83 and 1988-92)...
- Is the spatial distribution of brain lesions associated with closed-head injury in children predictive of subsequent development of posttraumatic stress disorder?Edward H Herskovits
Division of Neuroradiology, Johns Hopkins Medical Institutions, 600 N Wolfe St, Baltimore, MD 21287 7619, USA
Radiology 224:345-51. 2002....
- Diffusion tensor MR imaging in pediatric head traumaErhan Akpinar
Division of Emergency Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
J Comput Assist Tomogr 31:657-61. 2007..We propose to investigate the fractional anisotropy (FA) values in pediatric patients with closed head trauma and correlate them with the initial Glasgow Coma Scale (GCS)...
- Differential responses in three thalamic nuclei in moderately disabled, severely disabled and vegetative patients after blunt head injuryWilliam L Maxwell
Laboratory of Human Anatomy, Thomson Building, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
Brain 127:2470-8. 2004..In severely disabled and vegetative patients, loss of neurons from the ventral posterior thalamic nucleus may also reflect loss of response to afferent stimuli...
- Monkeybar injuries: complications of playM L Waltzman
Children s Hospital, Boston, Division of Emergency Medicine, Harvard Medical School, Boston MA 02115, USA
Pediatrics 103:e58. 1999..Equipment-specific injury requiring emergency department (ED) evaluation has not been reported previously...
- Patterns of maxillofacial injuries in powered watercraft collisionsJ I Garri
Department of General Surgery, University of Miami School of Medicine Jackson Memorial Hospital, Fla 33101, USA
Plast Reconstr Surg 104:922-7. 1999..Of 74 injuries 24 were facial fractures (32.4 percent), 18 were facial lacerations (24.3 percent), 14 were closed head injuries (18.9 percent), 8 were skull fractures (10.8 percent), 4 were scalp lacerations (5...
- Cheerleading-related injuries to children 5 to 18 years of age: United States, 1990-2002Brenda J Shields
Center for Injury Research and Policy, Columbus Children s Research Institute, Children s Hospital, Columbus, OH 43205 2664, USA
Pediatrics 117:122-9. 2006..To describe the epidemiology of cheerleading-related injuries among children in the United States...
- Severity of injuries associated with traumatic hip dislocation as a result of motor vehicle collisionsD J Hak
Section of Orthopaedic Surgery, The University of Michigan, Ann Arbor, USA
J Trauma 47:60-3. 1999..The purpose of this study was to review the associated injuries present in a current series of patients who sustained traumatic hip dislocation as a result of motor vehicle collisions...
- A history of loss of consciousness or post-traumatic amnesia in minor head injury: "conditio sine qua non" or one of the risk factors?M Smits
Department of Radiology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands
J Neurol Neurosurg Psychiatry 78:1359-64. 2007..The purpose of this study was to evaluate whether known risk factors for complications after MHI in the absence of LOC/PTA have the same predictive value as when LOC/PTA are present...
- The neuropsychology of blunt head injury in the early postacute stage: effects of focal lesions and diffuse axonal injuryC W Wallesch
Department of Neurology, Otto von Guericke University, Magdeburg, Germany
J Neurotrauma 18:11-20. 2001..In consideration of its easy accessibility, the refined use of the CT is considered a promising and valid tool for patient stratification. The application of MRI and biochemical markers may further improve prognostic predictions...
- Patients with moderate head injury: a prospective multicenter study of 315 patientsChristian Compagnone
Intensive Care Unit, Bufalini Hospital, Cesena, Italy
Neurosurgery 64:690-6; discussion 696-7. 2009..To analyze the risk factors of worst outcome associated with moderate head injury...
- 300 all-terrain vehicle crashes: an East Tennessee trauma center's experienceGeorge M Testerman
Wellmont Holston Valley Medical Center, Kingsport, USA
Tenn Med 102:45-7. 2009..A retrospective data review from a Level 1 trauma center trauma registry presents injury characteristics and outcomes, comparing patients in earlier and later time periods...
- There is differential loss of pyramidal cells from the human hippocampus with survival after blunt head injuryW L Maxwell
Department of Anatomy, IBLS, University of Glasgow, Glasgow, United Kingdom
J Neuropathol Exp Neurol 62:272-9. 2003..Second, there is an ongoing loss of neurons in sub-field CA1 and, most notably, in sub-field CA4, in patients surviving for more than 6 months. However, in neither group of patients is there loss of neurons from sub-field CA2...
- Pathology of blast-related brain injuryJeffery D Kocsis
Yale University School of Medicine, Neuroscience Research Center 127A, VA CT Healthcare System, West Haven, CT 06516, USA
J Rehabil Res Dev 46:667-72. 2009..little study, although it has been assumed to include the focal and diffuse lesions characteristic of closed head injuries. Available clinical studies of blast injuries show focal damage similar to that found in other types of ..
- Introduction: military neurosurgery, past and presentPaul Klimo
88th Medical Group, Wright Patterson Air Force Base, Ohio, USA
Neurosurg Focus 28:Introduction. 2010..After reading these articles, the reader will come away with an appreciation of the often complex nature of wartime penetrating and closed-head injuries and the remarkable recovery that many injured soldiers make with time...
- Early neurosurgical procedures enhance survival in blunt head injury: propensity score analysisJerris R Hedges
Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health and Science University, Portland, Oregon, USA
J Emerg Med 37:115-23. 2009..Traditional observational outcome studies have been biased because injury severity and clinical prognosis are associated with use of such interventions...
- Homicidal firearm injuries: a study from Sri LankaP A S Edirisinghe
Department of Forensic Medicine, University of Kelaniya, Thallagolla Road, Ragama, Sri Lanka
Forensic Sci Med Pathol 6:93-8. 2010..7 fatal shots per victim. This study demonstrates that firearm homicides in Sri Lanka mainly involve young men, and that when related to armed conflict the fatal injury usually consists of a single shot to the head or chest...
- Routinely repeated computed tomography after blunt head trauma: does it benefit patients?Krista L Kaups
Department of Surgery, 4th Floor, University Medical Center, 445 South Cedar Avenue, Fresno, CA 93702, USA
J Trauma 56:475-80; discussion 480-1. 2004..In the absence of clinical indications, routinely repeated HCT, even in patients with significant brain injury, does not contribute to patient care...
- [Primary loss of consciousness and amnesia in subarachnoid hemorrhage--a quantitative study]C J Lang
Neurologische Klinik mit Poliklinik der Friedrich Alexander Universität Erlangen Nuremberg, Germany
Zentralbl Neurochir 65:18-24. 2004..SAH therefore are events which with respect to LOC and amnesia bear some resemblance with closed head injuries. Exact observation and history taking may disclose important data on their severity and possible sequelae.
- Outcome after mild-to-moderate blunt head injury: effects of focal lesions and diffuse axonal injuryC W Wallesch
Department of Neurology, Otto von Guericke University, Magdeburg, Germany
Brain Inj 15:401-12. 2001..A comparison of the effects of focal and diffuse axonal injury in mild-to-moderate traumatic brain injury (TBI)...
- [Nosologic aspects of personality change due to head trauma]C A Pelegrín-Valero
Servicio de Psiquiatria, Hospital Miguel Servet, Zaragoza, Espana
Rev Neurol 32:681-7. 2001..Personality change due to head injury is one of the most prevalent neuropsychiatric posttraumatic disorders and causes significant impairment in familial, social or occupational functioning...
- Management of accidental minor head injuries in children: a prospective outcomes studyMark S Dias
Department of Pediatrics Division of Emergency Medicine, Center for Pediatric Quality, Women and Children s Hospital of Buffalo, State University of New York at Buffalo, New York, USA
J Neurosurg 101:38-43. 2004..and emergency department observation, rather than overnight admission, for children who have sustained accidental minor closed head injuries (Glasgow Coma Scale Scores 13-15) and who have met predefined clinical and radiographic criteria.
- Traumatic brainstem hemorrhage presenting with hemiparesisYoung Bem Se
Department of Neurosurgery, Hanyang University Guri Hospital, Guri, Korea
J Korean Neurosurg Soc 45:176-8. 2009..We should keep in mind the possibility of brainstem hemorrhage if supratentorial lesions or spinal cord lesions that caused neurological deficits in the head injured patients are unexplainable...
- Child abuse fatalities: are we missing opportunities for intervention?Wendalyn K King
Department of Pediatrics, Emory University, Atlanta, GA, USA
Pediatr Emerg Care 22:211-4. 2006..This study describes a cohort of fatally abused children and explores contacts with the health care community, which may represent missed opportunities for recognition and intervention...
- Quantitative analysis of ubiquitin-immunoreactivity in the midbrain periaqueductal gray matter with regard to the causes of death in forensic autopsyLi Quan
Department of Legal Medicine, Osaka City University Medical School, Asahi machi 1 4 3, Abeno, 545 8585 Osaka, Japan
Leg Med (Tokyo) 7:151-6. 2005....
- Prevention and treatment of post-traumatic epilepsyCarlo Alberto Pagni
Expert Rev Neurother 6:1223-33. 2006Post-traumatic epilepsy is reported after 2-5% of closed head injuries but up to 50% or more following penetrating head injury...
- Tree stands, not guns, are the midwestern hunter's most dangerous weaponAndrew Crockett
Department of Surgery, Division of Critical Care, Trauma, and Burn, The Ohio State University Medical Center, Columbus, Ohio, USA
Am Surg 76:1006-10. 2010..fractures, 47 per cent lower extremity fractures, 18 per cent upper extremity fractures, and 18 per cent closed head injuries. Surgery was required for 81 per cent of fall-related injuries, and 8...
- Traumatic intracranial hemorrhages in facial fracture patients: review of 2,195 patientsMatthias Hohlrieder
Department of Anesthesiology and Critical Care Medicine, University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria
Intensive Care Med 29:1095-100. 2003..This study examined which simple clinical signs identify facial fracture patients at risk for intracranial hemorrhage before the performance of computed tomography...
- Documented head injury in early adulthood and risk of Alzheimer's disease and other dementiasB L Plassman
Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
Neurology 55:1158-66. 2000..The association between antecedent head injury and AD is inconsistent...
- Lack of effect of induction of hypothermia after acute brain injuryG L Clifton
Vivian L Smith Center for Neurologic Research, Department of Neurosurgery, University of Texas Houston Medical School, 77030, USA
N Engl J Med 344:556-63. 2001..To study this issue, we conducted a multicenter trial comparing the effects of hypothermia with those of normothermia in patients with acute brain injury...
- Skull fracture as a herald of intracranial abnormality in children with mild head injury: is there a role for skull radiographs?Savvas Andronikou
Department of Paediatric Radiology, Red Cross Children s Hospital, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
Australas Radiol 47:381-5. 2003..All MHI with drainable collections had fractures. Fractures identified on SXR can be added to the clinical indications for CT in MHI and can improve detection of 'silent' drainable collections...
- Time course of CT evolution in traumatic subarachnoid haemorrhage: a study of 141 patientsE Fainardi
Unità Operativa di Neuroradiologia, Dipartimento di Neuroscienze, Arcispedale S Anna, Corso della Giovecca 203, 44100 Ferrara, Italy
Acta Neurochir (Wien) 146:257-63; discussion 263. 2004..Detection of these changes requires serial CT scanners. The goal of our study was to determine the optimal timing of follow-up CT scans in head injured patients with traumatic subarachnoid haemorrhage (tSAH)...
- Clinically suspected coagulopathy in blunt head traumaRon Medzon
Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA
J Emerg Med 39:399-405. 2010..CT scanning of the head should be performed initially based on clinical suspicion of coagulopathy...
- Beta-blockers in isolated blunt head injuryKenji Inaba
Division of Trauma Surgery and Surgical Critical Care, Department of Surgery, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA
J Am Coll Surg 206:432-8. 2008..The purpose of this study was to evaluate the effect of beta-blockers on patients sustaining acute traumatic brain injury. Our hypothesis was that beta-blocker exposure is associated with improved survival...
- NMDA Receptor Dynamics After Brain InjuryAnat Biegon; Fiscal Year: 2011..The results may explain the failure of NMDAR antagonists in clinical trials and suggest novel strategies for treatment of brain injury. ..
- Biological Inquiry into the Mechanisms and Neuroprotective Strategy for TBIDong Feng Chen; Fiscal Year: 2013..If the hypothesis is proven valid, an innovative technology that has strong implications for translation into clinical practice could be developed in the near future. ..
- Neurointensive Care and Assessment FacilityGlen N Gaulton; Fiscal Year: 2011..The facility will consist of 5 components: (1) a non-sterile procedure room for closed head injuries and terminal procedures, (2) an intensive care housing room, (3) a cognitive and behavioral assessment ..
- Status Epilepticus Outcomes in the United StatesEdwin Trevathan; Fiscal Year: 2001..stroke; (3) Using the NIS data, we will conduct four separate analyses to determine the factors that increase the odds of developing SE among inpatients with bacterial meningitis, viral encephalitis, closed head injuries, and/or stroke.
- HYPOTHERMIA AND TRAUMATIC BRAIN INJURYDonald Marion; Fiscal Year: 1993..Our results will provide the groundwork for a multicenter clinical trial of moderate hypothermia...
- SELECTIVE COMPUTED HEAD TOMOGRAPHY IN BLUNT TRAUMAWilliam Mower; Fiscal Year: 2000..Reduction in charges and radiation exposure will be determined by respectively summing radiographic charges and life- time decreases in radiation morbidity and mortality for all "no risk" cases. ..
- QUANTITATIVE BRAIN PERFUSION MEASUREMENTS WITH MRIDAVID PICKENS; Fiscal Year: 1993..to diseases of the brain, including disorders of intracranial pressure, traumatic conditions with closed head injuries, malignancy, cerebrovascular disease, and degenerative conditions...
- NEUROPSYCHOLOGICAL SEQUELAE OF PEDIATRIC HEAD INJURYJack Fletcher; Fiscal Year: 1993..neuro-behavioral follow-up studies of children (N=171) who sustained mild, moderate, and severe closed head injuries (CHI) at 0-15 years of age...
- EYE OPENER: A VEHICLE OPERATOR VIGILANCE MONITOR SYSTEMJ Hobson; Fiscal Year: 2001..proposed commercial application: not available ..
- Cognitive Recovery after Traumatic Brain InjuryMaureen Schmitter Edgecombe; Fiscal Year: 2007....
- Clinical Decision Rule to Identify Children with Intra-Abdominal InjuriesJames Holmes; Fiscal Year: 2008..unreadable]..
- Trauma to Immature Brain: Response Repair & TreatmentAnn Christine Duhaime; Fiscal Year: 2008..We believe this approach will help "bridge the gap" between rodent models and effective treatment for the many thousands of children who suffer traumatic brain injury each year. ..
- TRAUMA TO THE DEVELOPING BRAIN--RESPONSE AND TREATMENTAnn Christine Duhaime; Fiscal Year: 2002..This important information will be useful in the development and testing of head injury therapies appropriate for infants and children. ..
- PATHOPHYSIOLOGY OF THROMBOEMBOLIC STROKEW Dietrich; Fiscal Year: 2003..Neuroprotective strategies that may be given to patients with stroke risk factors to prevent the initiation of stroke will be tested. ..
- Marrow stromal cell deliver to repair the spinal cordJeffery Kocsis; Fiscal Year: 2007..abstract_text> ..
- Prevention of post-stroke depression-treatment strategyRobert Robinson; Fiscal Year: 2006..unreadable] [unreadable]..
- Genetic factors in outcome from traumatic brain injuryRamon Diaz Arrastia; Fiscal Year: 2008..These studies may provide genetic evidence for a role of specific genes in tissue response after TBI, and may identify novel targets for therapeutic intervention. ..
- Detecting Axonal Damage After Mild Traumatic Brain InjuryJeffrey Bazarian; Fiscal Year: 2009....
- Vascular depression and magnetic stimulation therapyRobert Robinson; Fiscal Year: 2005..e. more atrophy lower response rate) and cognitive function. ..
- Extended work schedules and health outcomes in the USGerald McGwin; Fiscal Year: 2002..Analyses will be adjusted for a number of possible confounders and effect modifier obtained from MEPS and NHIS including socio-demographic factors, family descriptors and lifestyle factors. ..
- Pathophysiology of glia following traumatic brain injuryRAIMONDO D AMBROSIO; Fiscal Year: 2005..Investigations on these post-traumatic changes will allow a more rational treatment to TBI. ..
- Posttraumatic epilepsy induced by fluid percussion injury in the ratRAIMONDO D apos AMBROSIO; Fiscal Year: 2010..abstract_text> ..
- Social Outcomes in Pediatric Traumatic Brain InjuryKeith O Yeates; Fiscal Year: 2010..By helping to better understand social outcomes after childhood TBI, the study's findings may suggest ways to promote children's behavioral adaptation to the functional losses and disabilities that frequently occur after TBI. ..
- Neural Architecture of Event ComprehensionJEFFREY ZACKS; Fiscal Year: 2008..unreadable] [unreadable]..
- Phonological codes and meaning access in readingJocelyn Folk; Fiscal Year: 2002..In addition, a more complete description of word recognition processes for skilled and less-skilled readers has implications for methods of reading instruction and remediation. ..
- Candidate genetic polymorphisms/ HIV-associated dementiaRamon Diaz Arrastia; Fiscal Year: 2002..These studies, is if successful, will provide genetic evidence for a role of specific inflammatory mediators in HAD, and may identify novel targets for therapeutic intervention. ..
- GENETIC EPIDEMIOLOGY OF ALZHEIMER'S DISEASE IN TWINSBrenda Plassman; Fiscal Year: 2003..A population-based twin design remains the ideal approach to these sorts of investigations. ..
- Effects of a Systematic Categorization Program in TBIFofi Constantinidou; Fiscal Year: 2004..The long-term objective of this research is to develop effective approaches to remediate complex cognitive processes such as categorization, decision-making and problem solving in patients with moderate to severe (TBI). ..
- POST CONCUSSIVE SYMPTOMS: CHILDREN WITH MILD HEAD INJURYKeith Yeates; Fiscal Year: 2005..The findings will help resolve the scientific controversy regarding the outcomes associated with mild CHI, and will assist physicians and other health care providers in identifying the sequelae of mild CHI and managing them effectively. ..
- Epidemiology of Traumatic Brain InjuryJeffrey Bazarian; Fiscal Year: 2005....
- Relationship of Hematocrit to Ischemic Stroke OutcomePaul Diamond; Fiscal Year: 2006..Fitting these models will result in a more complete understanding of the association between HCT and stroke outcome. Findings could lead to the development of new interventions to improve stroke outcome. [unreadable] [unreadable]..
- 23rd - 27th Annual National Neurotrauma SymposiumW Dietrich; Fiscal Year: 2005..In addition, there are two sessions for open communications as well as a panel discussions led by Women in Neurotrauma Research. Specific information regarding the organization of future meetings is also discussed. ..
- Mechanisms of Perceptual Extinction Following StrokeGordon Baylis; Fiscal Year: 2006..abstract_text> ..
- Hyperhomocysteinemia in Alzheimer's DiseaseRamon Diaz Arrastia; Fiscal Year: 2003..Each of these specific aims is essential to rationally design a large multicenter trial to determine whether polyvitamin therapy lowers AD risk. ..
- TRAUMA-RELATED ERYTHROPOIETIC SUPPRESSIONDavid Livingston; Fiscal Year: 2003..Understanding the mechanisms behind post-trauma anemia will allow therapeutic interventions improving endogenous erythropoiesis to be targeted. ..
- Outcomes of Traumatic Brain Injury in ChildrenKeith Yeates; Fiscal Year: 2007..and currently is Principal Investigator on an NICHD-funded research grant to study the outcomes of mild closed head injuries (CHI) in children and adolescents (see below)...
- BACTERIAL MEMBRANE PROTEINS IN GRAM-NEGATIVE SEPSISH Warren; Fiscal Year: 2008..The experiments are designed to evaluate the importance that physiologically relevant forms of MLP and PAL play in the pathophysiology of sepsis during infection. ..
- Evaluation of an Abusive Head Trauma Prevention ProgramWendy Lane; Fiscal Year: 2004..In addition rates of risk factors including poverty, teenage pregnancy, late prenatal care, low birth weight, and single parenthood among cases and controls will be compared. ..
- Mouse model for sepsisH Warren; Fiscal Year: 2009..abstract_text> ..
- New Frontiers in Pediatric Traumatic Brain InjuryKeith Yeates; Fiscal Year: 2007..unreadable] [unreadable] [unreadable] [unreadable]..