closed head injuries

Summary

Summary: Traumatic injuries to the cranium where the integrity of the skull is not compromised and no bone fragments or other objects penetrate the skull and dura mater. This frequently results in mechanical injury being transmitted to intracranial structures which may produce traumatic brain injuries, hemorrhage, or cranial nerve injury. (From Rowland, Merritt's Textbook of Neurology, 9th ed, p417)

Top Publications

  1. ncbi The use of clinical CCT images in the forensic examination of closed head injuries
    M Bauer
    Institute of Legal Medicine, University of Wuerzburg, Versbacher Strasse 3, 97078 Wuerzburg, Germany
    J Clin Forensic Med 11:65-70. 2004
  2. ncbi Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury
    Ido Yatsiv
    Pediatric Intensive Care Unit and Department of Pharmacology, Hebrew University Hadassah Medical Center, Jerusalem, Israel
    J Cereb Blood Flow Metab 22:971-8. 2002
  3. ncbi Erythropoietin is neuroprotective, improves functional recovery, and reduces neuronal apoptosis and inflammation in a rodent model of experimental closed head injury
    I Yatsiv
    Department of Pharmacology, School of Pharmacy, Hebrew University Hadassah Medical Center, Jerusalem, Israel
    FASEB J 19:1701-3. 2005
  4. ncbi Determinants of mortality in patients with severe blunt head injury
    Martin A Schreiber
    Department of Surgery, Baylor College of Medicine, Houston, TX, USA
    Arch Surg 137:285-90. 2002
  5. ncbi Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines
    P F Stahel
    Department of Surgery, University Hospital, Zurich, Switzerland
    J Cereb Blood Flow Metab 20:369-80. 2000
  6. ncbi Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice
    Mario Rancan
    Department of Trauma Surgery, The Alfred Hospital and Monash University, Melbourne, Victoria, Australia
    J Cereb Blood Flow Metab 23:1070-4. 2003
  7. ncbi The benefit of routine thoracic, abdominal, and pelvic computed tomography to evaluate trauma patients with closed head injuries
    Michael L Self
    Department of Surgery, Methodist Hospitals of Dallas, Dallas, TX, USA
    Am J Surg 186:609-13; discussion 613-4. 2003
  8. ncbi Intracerebral complement C5a receptor (CD88) expression is regulated by TNF and lymphotoxin-alpha following closed head injury in mice
    P F Stahel
    Department of Surgery, Division of Trauma Surgery and Division of Research, University Hospital, CH 8091, Zurich, Switzerland
    J Neuroimmunol 109:164-72. 2000
  9. ncbi Finite element modelling of human head injuries caused by a fall
    Jean Sebastien Raul
    Institut de Medecine Legale, 11 rue Humann, 67085 Strasbourg, France
    Int J Legal Med 120:212-8. 2006
  10. ncbi Hemostatic abnormalities in patients with closed head injuries and their role in predicting early mortality
    Vineet Saggar
    Department of Neurosurgery, S M S Medical College, Jaipur, India
    J Neurotrauma 26:1665-8. 2009

Research Grants

Detail Information

Publications236 found, 100 shown here

  1. ncbi The use of clinical CCT images in the forensic examination of closed head injuries
    M Bauer
    Institute of Legal Medicine, University of Wuerzburg, Versbacher Strasse 3, 97078 Wuerzburg, Germany
    J Clin Forensic Med 11:65-70. 2004
    ..To have unbiased access to these information, it is useful to evaluate the CT scans personally which requires a basic knowledge of traumatic changes found on radiographs...
  2. ncbi Elevated intracranial IL-18 in humans and mice after traumatic brain injury and evidence of neuroprotective effects of IL-18-binding protein after experimental closed head injury
    Ido Yatsiv
    Pediatric Intensive Care Unit and Department of Pharmacology, Hebrew University Hadassah Medical Center, Jerusalem, Israel
    J Cereb Blood Flow Metab 22:971-8. 2002
    ..However, brain edema at 24 hours was not influenced by IL-18BP, suggesting that inflammatory mediators other than IL-18 induce the early detrimental effects of intracerebral inflammation...
  3. ncbi Erythropoietin is neuroprotective, improves functional recovery, and reduces neuronal apoptosis and inflammation in a rodent model of experimental closed head injury
    I Yatsiv
    Department of Pharmacology, School of Pharmacy, Hebrew University Hadassah Medical Center, Jerusalem, Israel
    FASEB J 19:1701-3. 2005
    ..vehicle-treated animals. We propose that further studies on Epo in TBI should be conducted in order to consider it as a novel therapy for TBI...
  4. ncbi Determinants of mortality in patients with severe blunt head injury
    Martin A Schreiber
    Department of Surgery, Baylor College of Medicine, Houston, TX, USA
    Arch Surg 137:285-90. 2002
    ..Head injury is the leading cause of traumatic death in the United States...
  5. ncbi Experimental closed head injury: analysis of neurological outcome, blood-brain barrier dysfunction, intracranial neutrophil infiltration, and neuronal cell death in mice deficient in genes for pro-inflammatory cytokines
    P F Stahel
    Department of Surgery, University Hospital, Zurich, Switzerland
    J Cereb Blood Flow Metab 20:369-80. 2000
    ..Nevertheless, the increased posttraumatic mortality in TNF/LT-alpha-deficient mice suggests a protective effect of these cytokines by mechanisms that have not been elucidated yet...
  6. ncbi Central nervous system-targeted complement inhibition mediates neuroprotection after closed head injury in transgenic mice
    Mario Rancan
    Department of Trauma Surgery, The Alfred Hospital and Monash University, Melbourne, Victoria, Australia
    J Cereb Blood Flow Metab 23:1070-4. 2003
    ..This work further implicates the complement system as a participant in secondary progression of brain damage after head trauma and provides a strong rationale for future studies of posttraumatic pharmacologic complement inhibition...
  7. ncbi The benefit of routine thoracic, abdominal, and pelvic computed tomography to evaluate trauma patients with closed head injuries
    Michael L Self
    Department of Surgery, Methodist Hospitals of Dallas, Dallas, TX, USA
    Am J Surg 186:609-13; discussion 613-4. 2003
    ..We sought to evaluate the role of routine computed tomography (CT) of the chest, abdomen, and pelvis as a screening tool for patients already undergoing cranial CT studies...
  8. ncbi Intracerebral complement C5a receptor (CD88) expression is regulated by TNF and lymphotoxin-alpha following closed head injury in mice
    P F Stahel
    Department of Surgery, Division of Trauma Surgery and Division of Research, University Hospital, CH 8091, Zurich, Switzerland
    J Neuroimmunol 109:164-72. 2000
    ..These data show that the posttraumatic neuronal expression of the C5aR is, at least in part, regulated by TNF and lymphotoxin-alpha at 7 days after trauma...
  9. ncbi Finite element modelling of human head injuries caused by a fall
    Jean Sebastien Raul
    Institut de Medecine Legale, 11 rue Humann, 67085 Strasbourg, France
    Int J Legal Med 120:212-8. 2006
    ..We show that this tool can be used to discuss the possible mechanism of injury encountered for the observed lesions in a forensic case. It can also help to distinguish between possible and impossible human head injury mechanisms...
  10. ncbi Hemostatic abnormalities in patients with closed head injuries and their role in predicting early mortality
    Vineet Saggar
    Department of Neurosurgery, S M S Medical College, Jaipur, India
    J Neurotrauma 26:1665-8. 2009
    ..From this study we conclude that hemostatic abnormalities are independent predictors of early mortality in moderate-to-severe head injury patients...
  11. ncbi CT and MR imaging of acute cranial trauma
    James Provenzale
    Department of Radiology, Duke University Medical Center, Box 3808, Durham, NC 27710, USA
    Emerg Radiol 14:1-12. 2007
    ....
  12. ncbi Closed head injury--an inflammatory disease?
    Oliver I Schmidt
    Department of Trauma and Reconstructive Surgery, Charité University Medical School Berlin, Campus Benjamin Franklin, Germany
    Brain Res Brain Res Rev 48:388-99. 2005
    ....
  13. ncbi Automating 3D meshing method for patient-specific modeling
    Yabo Guan
    Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA
    Biomed Sci Instrum 42:199-204. 2006
    ..Both static and dynamic analyses were performed to verify the models. The study for blunt impact of infant head was performed by using these patient-specific models...
  14. ncbi Early predictors of mortality and morbidity after severe closed head injury
    E Lannoo
    Department of Neuropsychology and Rehabilitation, University Hospital, Gent, Belgium
    J Neurotrauma 17:403-14. 2000
    ..Those factors important for predicting mortality (clinical variables such as ICP or blood glucose level, and CT observations) failed to show any significant relationship with morbidity...
  15. ncbi Effects of head posture on cerebral hemodynamics: its influences on intracranial pressure, cerebral perfusion pressure, and cerebral oxygenation
    Ivan Ng
    Department of Neurosurgery, National Neuroscience Institute, and Faculty of Medicine, National University of Singapore, Singapore
    Neurosurgery 54:593-7; discussion 598. 2004
    ..We sought to determine the impact of supine and 30 degrees semirecumbent postures on cerebrovascular dynamics and global as well as regional cerebral oxygenation within 24 hours of trauma...
  16. ncbi Routine evaluation of the cervical spine in head-injured patients with dynamic fluoroscopy: a reappraisal
    J W Davis
    Division of Neurosurgery, Department of Surgery, University Medical Center, UCSF/Fresno, 445 South Cedar Ave, Fresno, CA 93702, USA
    J Trauma 50:1044-7. 2001
    ..If dynamic fluoroscopy is to be used, adherence to the protocol, including review of the cervical spine radiographs before fluoroscopy and visualization of the entire cervical spine, C1-T1, is mandatory to ensure patient safety...
  17. ncbi Intermittent burst-firing weak (1 microTesla) magnetic fields reduce psychometric depression in patients who sustained closed head injuries: a replication and electroencephalographic validation
    Laura Baker-Price
    Laurentian University, Sudbury, ON Canada
    Percept Mot Skills 96:965-74. 2003
    14 patients who reported chronic depression more than one year after closed head injuries were exposed to weak (1 microTesla), burst-firing magnetic fields either across the temporal lobes or over the left frontal lobe...
  18. ncbi Comparison of intracranial pressure measured in the cerebral cortex and the cerebellum of the rat
    Servan Rooker
    Department of Neurosurgery, University Hospital Antwerp, Wilrijkstraat 10, B 2650 Edegem, Antwerp, Belgium
    J Neurosci Methods 119:83-8. 2002
    ..We conclude that in rats the ICP measurement in the cerebellum is comparable to the ICP measurement in the cerebral cortex. The cerebellar ICP can be used as a valuable alternative during experimental procedures...
  19. ncbi Basic science of closed head injuries and spinal cord injuries
    David O Okonkwo
    Department of Neuroscience, University of Virginia, PO Box 800212, Charlottesville, VA 22908 0212, USA
    Clin Sports Med 22:467-81. 2003
    ..As no panacea exists, improvements in experimental models have empowered researchers in their search for novel therapeutic strategies...
  20. ncbi Do children require hospitalization after immediate posttraumatic seizures?
    James F Holmes
    Division of Emergency Medicine, Department of Internal Medicine, University of California Davis, School of Medicine, Sacramento, CA, USA
    Ann Emerg Med 43:706-10. 2004
    ..We determine whether children with immediate posttraumatic seizures require hospitalization for observation of possible neurologic complications...
  21. ncbi Ocular manifestations of head injury: a clinical study
    A R Kulkarni
    1Department of Ophthalmology, The Guest Hospital, Dudley Group of Hospitals NHS Trust, West Midlands, UK
    Eye (Lond) 19:1257-63. 2005
    ..This prospective study aimed to clinically correlate the various ocular findings with the neurological status in cases of closed head injury...
  22. ncbi Waiting for the patient to "sober up": Effect of alcohol intoxication on glasgow coma scale score of brain injured patients
    Jason L Sperry
    Division of Burns, Trauma and Surgical Critical Care, Department of Surgery, University of Texas Southwestern Medical School, Dallas, Texas 75390 9158, USA
    J Trauma 61:1305-11. 2006
    ..Alcohol intoxication may limit the ability of the Glasgow Coma Scale (GCS) to accurately assess severity of TBI. We hypothesized that alcohol intoxication significantly depresses GCS scores of TBI patients...
  23. ncbi Neuroplasticity following non-penetrating traumatic brain injury
    Harvey S Levin
    Cognitive Neuroscience Laboratory, Baylor College of Medicine, Houston, TX 77030, USA
    Brain Inj 17:665-74. 2003
    ..Functional MRI, coupled with DTI and possibly other imaging modalities holds the promise of elucidating mechanisms of neuroplasticity and repair following TBI...
  24. ncbi Olfactory dysfunction: a sequela of pediatric blunt head trauma
    Amanda A Sandford
    San Diego State University, Center for Lifespan Human Senses, Department of Psychology, 6363 Alvarado Court, Ste 101, San Diego, CA 92120 4913, USA
    Int J Pediatr Otorhinolaryngol 70:1015-25. 2006
    ..To evaluate olfactory function in children with blunt head trauma...
  25. ncbi [Recent findings in minor traumatic brain injury in sports]
    N Biasca
    Leiter Orthopädie und Sportmedizin, Leitender Arzt Traumatologie, Medical Consultant of the International Ice Hockey Federation IIHF, Spital Oberengadin, 7503 Samedan, Schweiz
    Zentralbl Chir 131:506-8. 2006
  26. ncbi [Diagnosis and management of patients with mild traumatic brain injury--an update with recommendations and future perspectives]
    O P Gautschi
    Department of Orthopaedic Surgery, Royal Perth Hospital, University of Western Australia, Perth
    Praxis (Bern 1994) 96:53-8; discussion 59-60. 2007
    ..Notably, the conventional X-ray is inadequate for the assessment of TBI. The following article discusses practical algorithms for the management of mild TBI and the indications for early use of CT...
  27. ncbi CT for acute stage of closed head injury
    Yoshihiro Toyama
    Department of Clinical Radiology, Faculty of Medicine, Kagawa University, Japan
    Radiat Med 23:309-16. 2005
    ..In this article, we review the imaging findings and literature of various lesions of closed head injury in the acute stage...
  28. ncbi Predictors of intracranial injuries in children after blunt head trauma
    Liviana Da Dalt
    Dipartimento di Pediatria, Universita di Padova, Via Giustiniani 3, 35128, Padova, Italy
    Eur J Pediatr 165:142-8. 2006
    ..The five-group classification of children allowed an excellent prediction in terms of likelihood of ICI (ROC area 0.972)...
  29. ncbi Traumatic interhemispheric subdural hematoma
    Yong xu Piao
    Department of Neurosurgery, Chengdu Military General Hospital, Chengdu 610083, China
    Chin J Traumatol 6:186-9. 2003
  30. ncbi Blunt cervical spine injuries in Scotland 1995-2000
    Elaine K Drainer
    Department of Accident and Emergency Medicine, Southern General Hospital, 1345 Govan Road, Glasgow G51 4TF, UK
    Injury 34:330-3. 2003
    ..This study aimed to evaluate the incidence of CSI in patients sustaining blunt head injuries in a Scottish population...
  31. ncbi Loss of consciousness and/or amnesia after blunt head trauma in children
    Nathan Kuppermann
    Pediatr Crit Care Med 6:93-4. 2005
  32. ncbi Necessity of hospital admission for pediatric minor head injury
    Matthew T Spencer
    Department of Emergency Medicine, University of Rochester Medical Center, Rochester, NY 14642, USA
    Am J Emerg Med 21:111-4. 2003
    ..We conclude that pediatric patients with MHI and negative CT scans of the head do not require routine admission for observation for delayed complications...
  33. ncbi Diagnosis and management of pediatric closed head injury
    Sami Khoshyomn
    Division of Neurosurgery, University of Vermont, 111 Colchester Avenue, Fletcher 5, Burlington, VT 05401, USA
    Semin Pediatr Surg 13:80-6. 2004
    ..In this article, early diagnosis and initial management of the most common forms of pediatric closed head injury are reviewed...
  34. ncbi Controversies in the evaluation and management of minor blunt head trauma in children
    David Schnadower
    Division of Pediatric Emergency Medicine, Morgan Stanley Children s Hospital of New York Presbyterian, Columbia University College of Physicians and Surgeons, 622 West 168th Street, New York, NY 10032, USA
    Curr Opin Pediatr 19:258-64. 2007
    ..We present data from recently conducted research regarding controversial aspects of the evaluation and management of children with minor blunt head trauma...
  35. ncbi Indications for routine repeat head computed tomography (CT) stratified by severity of traumatic brain injury
    Carlos V R Brown
    Department of Surgery, Division of Trauma and Critical Care, Los Angeles County and University of Southern California Medical Center, Los Angeles, California, USA
    J Trauma 62:1339-44; discussion 1344-5. 2007
    ..The specific aim of this study is to identify patients with head injuries who would benefit from a routine repeat head CT...
  36. ncbi Isolated oculomotor palsy following minor head trauma
    Richard L Levy
    Wilmer Eye Institute, Johns Hopkins Hospital, Baltimore, MD, USA
    Neurology 65:169. 2005
  37. ncbi The "CT comma sign" in head trauma: concurrent epidural and subdural acute intracranial hematomas
    Guillermo A Monsalve
    Department of Neurosurgery, Hospital Militar Central, Bogota, Colombia
    J Trauma 63:195-6. 2007
  38. ncbi Injuries from motorcycle- and moped crashes in Sweden from 1987 to 1999
    Magnus Aare
    Department of Aeronautics, Royal Institute of Technology, 10044 Stockholm, Sweden
    Inj Control Saf Promot 10:131-8. 2003
    ..Concussion was the most frequent head injury. Focal and diffuse brain injuries combined showed the same frequency as concussion. It is concluded that more preventative strategies must be presented before the injury rate can be reduced...
  39. ncbi The effect of fresh frozen plasma in severe closed head injury
    Hamid Etemadrezaie
    Neurosurgical Department, Shahid Kamyab Emdadi Hospital, Mashhad University of Medical Sciences MUMS, Mashhad, Iran
    Clin Neurol Neurosurg 109:166-71. 2007
    ..In this study we evaluated the effect of fresh frozen plasma (FFP) on the reduction in the incidence of DTICH in severe closed head injury victims...
  40. ncbi Understanding predictors of functional recovery and outcome 30 months following early childhood head injury
    Vicki A Anderson
    Department of Psychology, University of Melbourne, Royal Children s Hospital, Melbourne, Vic, Australia
    Neuropsychology 20:42-57. 2006
    ..In conclusion, children with more severe injuries and lower preinjury adaptive abilities, and whose families are coping poorly, are at greatest risk of long-term impairment in day-to-day skills, even several years postinjury...
  41. ncbi Does an isolated history of loss of consciousness or amnesia predict brain injuries in children after blunt head trauma?
    Michael J Palchak
    Division of Emergency Medicine, Department of Internal Medicine, University of California, Davis School of Medicine, Davis, California 95817 2282, USA
    Pediatrics 113:e507-13. 2004
    ..A history of loss of consciousness (LOC) is frequently used as an indication for cranial computed tomography (CT) in the emergency department (ED) evaluation of children with blunt head trauma...
  42. ncbi Reliability of clinical guidelines in the detection of patients at risk following mild head injury: results of a prospective study
    Javier Ibanez
    Department of Neurosurgery, Vall d Hebron University Hospital, Barcelona, Spain
    J Neurosurg 100:825-34. 2004
    ....
  43. ncbi Pediatric minor closed head injury
    Mary L Thiessen
    Department of Emergency Medicine, University of Arizona, 1515 North Campbell Avenue, Tucson, AZ 85724, USA
    Pediatr Clin North Am 53:1-26, v. 2006
    ..Evidence strongly supports a lower threshold to perform a CT scan in younger children because they have a higher risk of significant brain injury after blunt head trauma...
  44. ncbi Loss of consciousness: when to perform computed tomography?
    Michelle K Halley
    Children s Hospital and Health Center, San Diego, CA 92123, USA
    Pediatr Crit Care Med 5:230-3. 2004
    ....
  45. ncbi Epidemiology of blunt head injury victims undergoing ED cranial computed tomographic scanning
    James F Holmes
    Department of Emergency Medicine, UC Davis School of Medicine, Sacramento, CA 95817, USA
    Am J Emerg Med 24:167-73. 2006
    ..We sought to describe the epidemiology of emergency department (ED) patients with blunt head injury undergoing cranial computed tomography (CT) scanning for the evaluation of possible traumatic brain injury (TBI)...
  46. ncbi [Nursing children with head injuries]
    Monika Hinkeldey
    Kinderkrankenschwester und Fachschwester fur Internsivmedizin im Kindesalter Klinik und Poliklinik fur Kinferchirurgue des Universitätsklinikums Leipzig
    Kinderkrankenschwester 23:63-8. 2004
  47. ncbi Evaluation of mild head injury in a pediatric population
    Burak O Boran
    2nd Neurosurgery Clinic, Dr Lutfi Kirdar Kartal Research and Training Hospital, Istanbul, Turkey
    Pediatr Neurosurg 42:203-7. 2006
    ....
  48. ncbi [The undetected brain lesion in sports. Minor traumatic brain injury and its sequelae]
    N Biasca
    Traumatologie, Orthopädie und Sportmedizin, Medical Consultant of the International Ice Hockey Federation IIHF, Spital Oberengadin, Samedan, Schweiz
    Unfallchirurg 109:101-11. 2006
    ..In the future biochemical markers may serve as indicators of the severity of the brain injury and may also aid in predicting the outcome after TBI. Today biochemical markers do not serve as a substitute for neuroimaging...
  49. ncbi Working memory after mild, moderate, or severe childhood closed head injury
    Caroline Roncadin
    Department of Psychology, Hospital for Sick Children, Toronto, Ontario, Canada
    Dev Neuropsychol 25:21-36. 2004
    ..Age at injury and time since injury predicted WM components only for the moderate group. Survivors of moderate or severe childhood CHI have persisting WM deficits limiting the computational workspace required for many cognitive tasks...
  50. ncbi The impact of mild developmental learning difficulties on neuropsychological recovery from head trauma
    Rodger L L Wood
    Department of Psychology, University of Wales Swansea, Swansea, Wales, UK
    Brain Inj 20:477-84. 2006
    ..To investigate the prevalence of mild developmental learning difficulties (MDLD) in a group of patients who had sustained head trauma, to determine the impact on cognitive and neurobehavioural recovery...
  51. ncbi Defining "therapeutically inconsequential" head computed tomographic findings in patients with blunt head trauma
    Clare Atzema
    Emergency Medicine Center, University of California Los Angeles School of Medicine, Los Angeles, CA 90024, USA
    Ann Emerg Med 44:47-56. 2004
    ..quot; We estimate the prevalence of these findings and determine how frequently affected patients had "important neurosurgical outcomes," defined as either a directed intervention or a poor Glasgow Outcome Scale score...
  52. ncbi Performance of a decision rule to predict need for computed tomography among children with blunt head trauma
    Jennifer A Oman
    Department of Emergency Medicine, College of Medicine, University of California, Irvine, California, USA
    Pediatrics 117:e238-46. 2006
    ..To assess the ability of the NEXUS II head trauma decision instrument to identify patients with clinically important intracranial injury (ICI) from among children with blunt head trauma...
  53. ncbi Large animal models of traumatic injury to the immature brain
    Ann Christine Duhaime
    Pediatric Neurosurgery, Children s Hospital at Dartmouth, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Dev Neurosci 28:380-7. 2006
    ..Progress to date and future directions are outlined...
  54. ncbi Diffusion-weighted MR imaging in closed head injury: high correlation with initial glasgow coma scale score and score on modified Rankin scale at discharge
    Pamela W Schaefer
    Department of Radiology, Massachusetts General Hospital, 55 Fruit St, Gray B285, Boston, MA 02114, USA
    Radiology 233:58-66. 2004
    ..To determine whether diffusion-weighted magnetic resonance (MR) imaging findings and conventional MR imaging findings correlate with initial Glasgow Coma Scale score and score on modified Rankin scale at discharge...
  55. ncbi Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury
    Lauralyn A McIntyre
    Centre for Transfusion and Critical Care Research, Clinical Epidemiology Unit, Critical Care Program, University of Ottawa and Ottawa Health Research Institute, Ottawa, Ontario
    Neurocrit Care 5:4-9. 2006
    ..To compare a restrictive versus a liberal transfusion strategy in patients with moderate to severe closed head injury following multiple trauma in 13 Canadian intensive care units (ICUs)...
  56. ncbi Hyperacute head injuries and the timing of computed tomography
    Andreas K Demetriades
    Department of Neurosurgery, National Hospital for Neurology and Neurosurgery, Queen Square, London, UK
    J Trauma 57:925. 2004
  57. ncbi Indications for brain CT scan in patients with minor head injury
    Masih Saboori
    Department of Neurosurgery, Medical School, Medical University of Isfahan, Isfahan, Iran
    Clin Neurol Neurosurg 109:399-405. 2007
    ..The aim of this study was to find clinical signs and symptoms which help to predict the indications for brain CT scan following minor head injury...
  58. ncbi [Minor craniocerebral trauma]
    D Scharplatz
    Chirurgische Abteilung, Spital Thusis
    Praxis (Bern 1994) 91:1428-31. 2002
    ..Wherever computerized tomography (CT) is available, a CT examination is broadly indicated. There is no knowledge of any adverse effects on patients whose GCS worsened when the CT revealed normal findings...
  59. ncbi A picture worth remembering: posttraumatic Purtscher's retinopathy in a child
    Charuta Joshi
    Section of Pediatric Neurology, Chidren s Hospital, Winnipeg, Manitoba, Canada
    J Child Neurol 23:353-5. 2008
    ..The case of a 6-year-old girl with Purtscher's retinopathy is described, and the relevant literature is reviewed...
  60. ncbi Appearances are deceptive? Long-term cognitive and central auditory sequelae from closed head injury
    Per Olof Bergemalm
    Ahlsen Research Institute, Orebro University Hospital, Sweden
    Int J Audiol 44:39-49. 2005
    ..The cognitive tasks used in the study have proved to be a sensitive method to discover cognitive impairments. Long-term cognitive sequelae and APD could not be predicted from RLS scores...
  61. ncbi Effect of impact on different regions of the head of lambs
    J W Finnie
    Veterinary Services Division and Neuropathology Laboratory, Institute of Medical and Veterinary Science, Adelaide, South Australia 5000, Australia
    J Comp Pathol 124:159-64. 2001
    ..The findings should assist clinicians in evaluating the probable outcome of traumatic head injury in domestic animals. Copyright Harcourt Publishers Ltd...
  62. ncbi Damage to intracranial optic pathways in fatal closed head injury in man
    B Perunovic
    Department of Neuropathology, Frenchay Hospital, Bristol BS161LE, UK
    J Neurol Sci 185:55-62. 2001
    ..The findings suggest that damage to the posterior parts of the optic pathways may be under-diagnosed among patients with head injury...
  63. ncbi Pediatric minor head trauma: indications for computed tomographic scanning revisited
    B Simon
    Baystate Medical Center, Springfield, Massachusetts, USA
    J Trauma 51:231-7; discussion 237-8. 2001
    ..A liberal policy of CT scanning is warranted for pediatric patients with a high-risk mechanism of injury despite maintenance of normal neurologic status in the field and at hospital screening...
  64. doi Massive subgaleal hematoma
    Rafael de Oliveira Sillero
    Department of Neurosurgery, Faculdade de Medicina de Botucatu, Universidade Estadual Paulista, Botucatu, Sao Paulo, Brazil
    J Trauma 65:963. 2008
  65. ncbi Reimaging in pediatric neurotrauma: factors associated with progression of intracranial injury
    Andy Givner
    Department of Surgery, Walter Reed Army Hospital, Division of Neuroradiology Surgery, Boston University School of Medicine, Boston, MA, USA
    J Pediatr Surg 37:381-5. 2002
    ....
  66. ncbi Computed tomographic brain density measurement as a predictor of elevated intracranial pressure in blunt head trauma
    Kenji Inaba
    Division of Trauma Surgery and Surgical Critical Care, University of Southern California, Los Angeles, California 90033, USA
    Am Surg 73:1023-6. 2007
    ..6 HU) versus CPP 70 or greater (26.2, P = 0.436). CT-measured brain density does not correlate with elevated ICP or depressed CPP and cannot predict patients with traumatic brain injury who would benefit from invasive ICP monitoring...
  67. ncbi Selective alexia and agraphia sparing numbers-a case study
    Randi Starrfelt
    Department of Psychology, University of Copenhagen, Linnesgade 22, DK 1361, Copenhagen, Denmark
    Brain Lang 102:52-63. 2007
    ..We suggest that a deficit in a visuo-motor network containing knowledge of the physical shape of letters might explain the pattern of performance displayed by MT...
  68. ncbi Severe traumatic brain injury in children--are the results improving?
    Jurg Pfenninger
    Pediatric Intensive Care Unit, University Children s Hospital, Inselspital, Bern, Switzerland
    Swiss Med Wkly 132:116-20. 2002
    ..Medical management is constantly being refined, and thus results should improve. The aim of the present study was to analyse our data of recent years and to compare them with previous series (1978-83 and 1988-92)...
  69. ncbi Is the spatial distribution of brain lesions associated with closed-head injury in children predictive of subsequent development of posttraumatic stress disorder?
    Edward H Herskovits
    Division of Neuroradiology, Johns Hopkins Medical Institutions, 600 N Wolfe St, Baltimore, MD 21287 7619, USA
    Radiology 224:345-51. 2002
    ....
  70. ncbi Diffusion tensor MR imaging in pediatric head trauma
    Erhan Akpinar
    Division of Emergency Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    J Comput Assist Tomogr 31:657-61. 2007
    ..We propose to investigate the fractional anisotropy (FA) values in pediatric patients with closed head trauma and correlate them with the initial Glasgow Coma Scale (GCS)...
  71. ncbi Differential responses in three thalamic nuclei in moderately disabled, severely disabled and vegetative patients after blunt head injury
    William L Maxwell
    Laboratory of Human Anatomy, Thomson Building, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
    Brain 127:2470-8. 2004
    ..In severely disabled and vegetative patients, loss of neurons from the ventral posterior thalamic nucleus may also reflect loss of response to afferent stimuli...
  72. ncbi Monkeybar injuries: complications of play
    M L Waltzman
    Children s Hospital, Boston, Division of Emergency Medicine, Harvard Medical School, Boston MA 02115, USA
    Pediatrics 103:e58. 1999
    ..Equipment-specific injury requiring emergency department (ED) evaluation has not been reported previously...
  73. ncbi Patterns of maxillofacial injuries in powered watercraft collisions
    J I Garri
    Department of General Surgery, University of Miami School of Medicine Jackson Memorial Hospital, Fla 33101, USA
    Plast Reconstr Surg 104:922-7. 1999
    ..Of 74 injuries 24 were facial fractures (32.4 percent), 18 were facial lacerations (24.3 percent), 14 were closed head injuries (18.9 percent), 8 were skull fractures (10.8 percent), 4 were scalp lacerations (5...
  74. ncbi Cheerleading-related injuries to children 5 to 18 years of age: United States, 1990-2002
    Brenda J Shields
    Center for Injury Research and Policy, Columbus Children s Research Institute, Children s Hospital, Columbus, OH 43205 2664, USA
    Pediatrics 117:122-9. 2006
    ..To describe the epidemiology of cheerleading-related injuries among children in the United States...
  75. ncbi Severity of injuries associated with traumatic hip dislocation as a result of motor vehicle collisions
    D J Hak
    Section of Orthopaedic Surgery, The University of Michigan, Ann Arbor, USA
    J Trauma 47:60-3. 1999
    ..The purpose of this study was to review the associated injuries present in a current series of patients who sustained traumatic hip dislocation as a result of motor vehicle collisions...
  76. pmc A history of loss of consciousness or post-traumatic amnesia in minor head injury: "conditio sine qua non" or one of the risk factors?
    M Smits
    Department of Radiology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands
    J Neurol Neurosurg Psychiatry 78:1359-64. 2007
    ..The purpose of this study was to evaluate whether known risk factors for complications after MHI in the absence of LOC/PTA have the same predictive value as when LOC/PTA are present...
  77. ncbi The neuropsychology of blunt head injury in the early postacute stage: effects of focal lesions and diffuse axonal injury
    C W Wallesch
    Department of Neurology, Otto von Guericke University, Magdeburg, Germany
    J Neurotrauma 18:11-20. 2001
    ..In consideration of its easy accessibility, the refined use of the CT is considered a promising and valid tool for patient stratification. The application of MRI and biochemical markers may further improve prognostic predictions...
  78. ncbi Patients with moderate head injury: a prospective multicenter study of 315 patients
    Christian Compagnone
    Intensive Care Unit, Bufalini Hospital, Cesena, Italy
    Neurosurgery 64:690-6; discussion 696-7. 2009
    ..To analyze the risk factors of worst outcome associated with moderate head injury...
  79. ncbi 300 all-terrain vehicle crashes: an East Tennessee trauma center's experience
    George M Testerman
    Wellmont Holston Valley Medical Center, Kingsport, USA
    Tenn Med 102:45-7. 2009
    ..A retrospective data review from a Level 1 trauma center trauma registry presents injury characteristics and outcomes, comparing patients in earlier and later time periods...
  80. ncbi There is differential loss of pyramidal cells from the human hippocampus with survival after blunt head injury
    W L Maxwell
    Department of Anatomy, IBLS, University of Glasgow, Glasgow, United Kingdom
    J Neuropathol Exp Neurol 62:272-9. 2003
    ..Second, there is an ongoing loss of neurons in sub-field CA1 and, most notably, in sub-field CA4, in patients surviving for more than 6 months. However, in neither group of patients is there loss of neurons from sub-field CA2...
  81. ncbi Pathology of blast-related brain injury
    Jeffery D Kocsis
    Yale University School of Medicine, Neuroscience Research Center 127A, VA CT Healthcare System, West Haven, CT 06516, USA
    J Rehabil Res Dev 46:667-72. 2009
    ..little study, although it has been assumed to include the focal and diffuse lesions characteristic of closed head injuries. Available clinical studies of blast injuries show focal damage similar to that found in other types of ..
  82. ncbi Introduction: military neurosurgery, past and present
    Paul Klimo
    88th Medical Group, Wright Patterson Air Force Base, Ohio, USA
    Neurosurg Focus 28:Introduction. 2010
    ..After reading these articles, the reader will come away with an appreciation of the often complex nature of wartime penetrating and closed-head injuries and the remarkable recovery that many injured soldiers make with time...
  83. ncbi Early neurosurgical procedures enhance survival in blunt head injury: propensity score analysis
    Jerris R Hedges
    Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health and Science University, Portland, Oregon, USA
    J Emerg Med 37:115-23. 2009
    ..Traditional observational outcome studies have been biased because injury severity and clinical prognosis are associated with use of such interventions...
  84. ncbi Homicidal firearm injuries: a study from Sri Lanka
    P A S Edirisinghe
    Department of Forensic Medicine, University of Kelaniya, Thallagolla Road, Ragama, Sri Lanka
    Forensic Sci Med Pathol 6:93-8. 2010
    ..7 fatal shots per victim. This study demonstrates that firearm homicides in Sri Lanka mainly involve young men, and that when related to armed conflict the fatal injury usually consists of a single shot to the head or chest...
  85. ncbi Routinely repeated computed tomography after blunt head trauma: does it benefit patients?
    Krista L Kaups
    Department of Surgery, 4th Floor, University Medical Center, 445 South Cedar Avenue, Fresno, CA 93702, USA
    J Trauma 56:475-80; discussion 480-1. 2004
    ..In the absence of clinical indications, routinely repeated HCT, even in patients with significant brain injury, does not contribute to patient care...
  86. ncbi [Primary loss of consciousness and amnesia in subarachnoid hemorrhage--a quantitative study]
    C J Lang
    Neurologische Klinik mit Poliklinik der Friedrich Alexander Universität Erlangen Nuremberg, Germany
    Zentralbl Neurochir 65:18-24. 2004
    ..SAH therefore are events which with respect to LOC and amnesia bear some resemblance with closed head injuries. Exact observation and history taking may disclose important data on their severity and possible sequelae.
  87. ncbi Outcome after mild-to-moderate blunt head injury: effects of focal lesions and diffuse axonal injury
    C W Wallesch
    Department of Neurology, Otto von Guericke University, Magdeburg, Germany
    Brain Inj 15:401-12. 2001
    ..A comparison of the effects of focal and diffuse axonal injury in mild-to-moderate traumatic brain injury (TBI)...
  88. ncbi [Nosologic aspects of personality change due to head trauma]
    C A Pelegrín-Valero
    Servicio de Psiquiatria, Hospital Miguel Servet, Zaragoza, Espana
    Rev Neurol 32:681-7. 2001
    ..Personality change due to head injury is one of the most prevalent neuropsychiatric posttraumatic disorders and causes significant impairment in familial, social or occupational functioning...
  89. ncbi Management of accidental minor head injuries in children: a prospective outcomes study
    Mark S Dias
    Department of Pediatrics Division of Emergency Medicine, Center for Pediatric Quality, Women and Children s Hospital of Buffalo, State University of New York at Buffalo, New York, USA
    J Neurosurg 101:38-43. 2004
    ..and emergency department observation, rather than overnight admission, for children who have sustained accidental minor closed head injuries (Glasgow Coma Scale Scores 13-15) and who have met predefined clinical and radiographic criteria.
  90. pmc Traumatic brainstem hemorrhage presenting with hemiparesis
    Young Bem Se
    Department of Neurosurgery, Hanyang University Guri Hospital, Guri, Korea
    J Korean Neurosurg Soc 45:176-8. 2009
    ..We should keep in mind the possibility of brainstem hemorrhage if supratentorial lesions or spinal cord lesions that caused neurological deficits in the head injured patients are unexplainable...
  91. ncbi Child abuse fatalities: are we missing opportunities for intervention?
    Wendalyn K King
    Department of Pediatrics, Emory University, Atlanta, GA, USA
    Pediatr Emerg Care 22:211-4. 2006
    ..This study describes a cohort of fatally abused children and explores contacts with the health care community, which may represent missed opportunities for recognition and intervention...
  92. ncbi Quantitative analysis of ubiquitin-immunoreactivity in the midbrain periaqueductal gray matter with regard to the causes of death in forensic autopsy
    Li Quan
    Department of Legal Medicine, Osaka City University Medical School, Asahi machi 1 4 3, Abeno, 545 8585 Osaka, Japan
    Leg Med (Tokyo) 7:151-6. 2005
    ....
  93. ncbi Prevention and treatment of post-traumatic epilepsy
    Carlo Alberto Pagni
    Expert Rev Neurother 6:1223-33. 2006
    Post-traumatic epilepsy is reported after 2-5% of closed head injuries but up to 50% or more following penetrating head injury...
  94. ncbi Tree stands, not guns, are the midwestern hunter's most dangerous weapon
    Andrew Crockett
    Department of Surgery, Division of Critical Care, Trauma, and Burn, The Ohio State University Medical Center, Columbus, Ohio, USA
    Am Surg 76:1006-10. 2010
    ..fractures, 47 per cent lower extremity fractures, 18 per cent upper extremity fractures, and 18 per cent closed head injuries. Surgery was required for 81 per cent of fall-related injuries, and 8...
  95. ncbi Traumatic intracranial hemorrhages in facial fracture patients: review of 2,195 patients
    Matthias Hohlrieder
    Department of Anesthesiology and Critical Care Medicine, University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria
    Intensive Care Med 29:1095-100. 2003
    ..This study examined which simple clinical signs identify facial fracture patients at risk for intracranial hemorrhage before the performance of computed tomography...
  96. ncbi Documented head injury in early adulthood and risk of Alzheimer's disease and other dementias
    B L Plassman
    Department of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, USA
    Neurology 55:1158-66. 2000
    ..The association between antecedent head injury and AD is inconsistent...
  97. ncbi Lack of effect of induction of hypothermia after acute brain injury
    G L Clifton
    Vivian L Smith Center for Neurologic Research, Department of Neurosurgery, University of Texas Houston Medical School, 77030, USA
    N Engl J Med 344:556-63. 2001
    ..To study this issue, we conducted a multicenter trial comparing the effects of hypothermia with those of normothermia in patients with acute brain injury...
  98. ncbi Skull fracture as a herald of intracranial abnormality in children with mild head injury: is there a role for skull radiographs?
    Savvas Andronikou
    Department of Paediatric Radiology, Red Cross Children s Hospital, School of Child and Adolescent Health, University of Cape Town, Cape Town, South Africa
    Australas Radiol 47:381-5. 2003
    ..All MHI with drainable collections had fractures. Fractures identified on SXR can be added to the clinical indications for CT in MHI and can improve detection of 'silent' drainable collections...
  99. ncbi Time course of CT evolution in traumatic subarachnoid haemorrhage: a study of 141 patients
    E Fainardi
    Unità Operativa di Neuroradiologia, Dipartimento di Neuroscienze, Arcispedale S Anna, Corso della Giovecca 203, 44100 Ferrara, Italy
    Acta Neurochir (Wien) 146:257-63; discussion 263. 2004
    ..Detection of these changes requires serial CT scanners. The goal of our study was to determine the optimal timing of follow-up CT scans in head injured patients with traumatic subarachnoid haemorrhage (tSAH)...
  100. ncbi Clinically suspected coagulopathy in blunt head trauma
    Ron Medzon
    Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA
    J Emerg Med 39:399-405. 2010
    ..CT scanning of the head should be performed initially based on clinical suspicion of coagulopathy...
  101. ncbi Beta-blockers in isolated blunt head injury
    Kenji Inaba
    Division of Trauma Surgery and Surgical Critical Care, Department of Surgery, University of Southern California, Keck School of Medicine, Los Angeles, CA 90033, USA
    J Am Coll Surg 206:432-8. 2008
    ..The purpose of this study was to evaluate the effect of beta-blockers on patients sustaining acute traumatic brain injury. Our hypothesis was that beta-blocker exposure is associated with improved survival...

Research Grants43

  1. NMDA Receptor Dynamics After Brain Injury
    Anat Biegon; Fiscal Year: 2011
    ..The results may explain the failure of NMDAR antagonists in clinical trials and suggest novel strategies for treatment of brain injury. ..
  2. Biological Inquiry into the Mechanisms and Neuroprotective Strategy for TBI
    Dong Feng Chen; Fiscal Year: 2013
    ..If the hypothesis is proven valid, an innovative technology that has strong implications for translation into clinical practice could be developed in the near future. ..
  3. Neurointensive Care and Assessment Facility
    Glen N Gaulton; Fiscal Year: 2011
    ..The facility will consist of 5 components: (1) a non-sterile procedure room for closed head injuries and terminal procedures, (2) an intensive care housing room, (3) a cognitive and behavioral assessment ..
  4. Status Epilepticus Outcomes in the United States
    Edwin Trevathan; Fiscal Year: 2001
    ..stroke; (3) Using the NIS data, we will conduct four separate analyses to determine the factors that increase the odds of developing SE among inpatients with bacterial meningitis, viral encephalitis, closed head injuries, and/or stroke.
  5. HYPOTHERMIA AND TRAUMATIC BRAIN INJURY
    Donald Marion; Fiscal Year: 1993
    ..Our results will provide the groundwork for a multicenter clinical trial of moderate hypothermia...
  6. SELECTIVE COMPUTED HEAD TOMOGRAPHY IN BLUNT TRAUMA
    William Mower; Fiscal Year: 2000
    ..Reduction in charges and radiation exposure will be determined by respectively summing radiographic charges and life- time decreases in radiation morbidity and mortality for all "no risk" cases. ..
  7. QUANTITATIVE BRAIN PERFUSION MEASUREMENTS WITH MRI
    DAVID PICKENS; Fiscal Year: 1993
    ..to diseases of the brain, including disorders of intracranial pressure, traumatic conditions with closed head injuries, malignancy, cerebrovascular disease, and degenerative conditions...
  8. NEUROPSYCHOLOGICAL SEQUELAE OF PEDIATRIC HEAD INJURY
    Jack Fletcher; Fiscal Year: 1993
    ..neuro-behavioral follow-up studies of children (N=171) who sustained mild, moderate, and severe closed head injuries (CHI) at 0-15 years of age...
  9. EYE OPENER: A VEHICLE OPERATOR VIGILANCE MONITOR SYSTEM
    J Hobson; Fiscal Year: 2001
    ..proposed commercial application: not available ..
  10. Cognitive Recovery after Traumatic Brain Injury
    Maureen Schmitter Edgecombe; Fiscal Year: 2007
    ....
  11. Clinical Decision Rule to Identify Children with Intra-Abdominal Injuries
    James Holmes; Fiscal Year: 2008
    ..unreadable]..
  12. Trauma to Immature Brain: Response Repair & Treatment
    Ann Christine Duhaime; Fiscal Year: 2008
    ..We believe this approach will help "bridge the gap" between rodent models and effective treatment for the many thousands of children who suffer traumatic brain injury each year. ..
  13. TRAUMA TO THE DEVELOPING BRAIN--RESPONSE AND TREATMENT
    Ann Christine Duhaime; Fiscal Year: 2002
    ..This important information will be useful in the development and testing of head injury therapies appropriate for infants and children. ..
  14. PATHOPHYSIOLOGY OF THROMBOEMBOLIC STROKE
    W Dietrich; Fiscal Year: 2003
    ..Neuroprotective strategies that may be given to patients with stroke risk factors to prevent the initiation of stroke will be tested. ..
  15. Marrow stromal cell deliver to repair the spinal cord
    Jeffery Kocsis; Fiscal Year: 2007
    ..abstract_text> ..
  16. Prevention of post-stroke depression-treatment strategy
    Robert Robinson; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  17. Genetic factors in outcome from traumatic brain injury
    Ramon Diaz Arrastia; Fiscal Year: 2008
    ..These studies may provide genetic evidence for a role of specific genes in tissue response after TBI, and may identify novel targets for therapeutic intervention. ..
  18. Detecting Axonal Damage After Mild Traumatic Brain Injury
    Jeffrey Bazarian; Fiscal Year: 2009
    ....
  19. Vascular depression and magnetic stimulation therapy
    Robert Robinson; Fiscal Year: 2005
    ..e. more atrophy lower response rate) and cognitive function. ..
  20. Extended work schedules and health outcomes in the US
    Gerald McGwin; Fiscal Year: 2002
    ..Analyses will be adjusted for a number of possible confounders and effect modifier obtained from MEPS and NHIS including socio-demographic factors, family descriptors and lifestyle factors. ..
  21. Pathophysiology of glia following traumatic brain injury
    RAIMONDO D AMBROSIO; Fiscal Year: 2005
    ..Investigations on these post-traumatic changes will allow a more rational treatment to TBI. ..
  22. Posttraumatic epilepsy induced by fluid percussion injury in the rat
    RAIMONDO D apos AMBROSIO; Fiscal Year: 2010
    ..abstract_text> ..
  23. Social Outcomes in Pediatric Traumatic Brain Injury
    Keith O Yeates; Fiscal Year: 2010
    ..By helping to better understand social outcomes after childhood TBI, the study's findings may suggest ways to promote children's behavioral adaptation to the functional losses and disabilities that frequently occur after TBI. ..
  24. Neural Architecture of Event Comprehension
    JEFFREY ZACKS; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  25. Phonological codes and meaning access in reading
    Jocelyn Folk; Fiscal Year: 2002
    ..In addition, a more complete description of word recognition processes for skilled and less-skilled readers has implications for methods of reading instruction and remediation. ..
  26. Candidate genetic polymorphisms/ HIV-associated dementia
    Ramon Diaz Arrastia; Fiscal Year: 2002
    ..These studies, is if successful, will provide genetic evidence for a role of specific inflammatory mediators in HAD, and may identify novel targets for therapeutic intervention. ..
  27. GENETIC EPIDEMIOLOGY OF ALZHEIMER'S DISEASE IN TWINS
    Brenda Plassman; Fiscal Year: 2003
    ..A population-based twin design remains the ideal approach to these sorts of investigations. ..
  28. Effects of a Systematic Categorization Program in TBI
    Fofi Constantinidou; Fiscal Year: 2004
    ..The long-term objective of this research is to develop effective approaches to remediate complex cognitive processes such as categorization, decision-making and problem solving in patients with moderate to severe (TBI). ..
  29. POST CONCUSSIVE SYMPTOMS: CHILDREN WITH MILD HEAD INJURY
    Keith Yeates; Fiscal Year: 2005
    ..The findings will help resolve the scientific controversy regarding the outcomes associated with mild CHI, and will assist physicians and other health care providers in identifying the sequelae of mild CHI and managing them effectively. ..
  30. Epidemiology of Traumatic Brain Injury
    Jeffrey Bazarian; Fiscal Year: 2005
    ....
  31. Relationship of Hematocrit to Ischemic Stroke Outcome
    Paul Diamond; Fiscal Year: 2006
    ..Fitting these models will result in a more complete understanding of the association between HCT and stroke outcome. Findings could lead to the development of new interventions to improve stroke outcome. [unreadable] [unreadable]..
  32. 23rd - 27th Annual National Neurotrauma Symposium
    W Dietrich; Fiscal Year: 2005
    ..In addition, there are two sessions for open communications as well as a panel discussions led by Women in Neurotrauma Research. Specific information regarding the organization of future meetings is also discussed. ..
  33. Mechanisms of Perceptual Extinction Following Stroke
    Gordon Baylis; Fiscal Year: 2006
    ..abstract_text> ..
  34. Hyperhomocysteinemia in Alzheimer's Disease
    Ramon Diaz Arrastia; Fiscal Year: 2003
    ..Each of these specific aims is essential to rationally design a large multicenter trial to determine whether polyvitamin therapy lowers AD risk. ..
  35. TRAUMA-RELATED ERYTHROPOIETIC SUPPRESSION
    David Livingston; Fiscal Year: 2003
    ..Understanding the mechanisms behind post-trauma anemia will allow therapeutic interventions improving endogenous erythropoiesis to be targeted. ..
  36. Outcomes of Traumatic Brain Injury in Children
    Keith Yeates; Fiscal Year: 2007
    ..and currently is Principal Investigator on an NICHD-funded research grant to study the outcomes of mild closed head injuries (CHI) in children and adolescents (see below)...
  37. BACTERIAL MEMBRANE PROTEINS IN GRAM-NEGATIVE SEPSIS
    H Warren; Fiscal Year: 2008
    ..The experiments are designed to evaluate the importance that physiologically relevant forms of MLP and PAL play in the pathophysiology of sepsis during infection. ..
  38. Evaluation of an Abusive Head Trauma Prevention Program
    Wendy Lane; Fiscal Year: 2004
    ..In addition rates of risk factors including poverty, teenage pregnancy, late prenatal care, low birth weight, and single parenthood among cases and controls will be compared. ..
  39. Mouse model for sepsis
    H Warren; Fiscal Year: 2009
    ..abstract_text> ..
  40. New Frontiers in Pediatric Traumatic Brain Injury
    Keith Yeates; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..