Genomes and Genes
Summary: Traumatic injuries involving the cranium and intracranial structures (i.e., BRAIN; CRANIAL NERVES; MENINGES; and other structures). Injuries may be classified by whether or not the skull is penetrated (i.e., penetrating vs. nonpenetrating) or whether there is an associated hemorrhage.
Publications355 found, 100 shown here
- Indications for computed tomography in patients with minor head injuryM J Haydel
Section of Emergency Medicine, Louisiana State University Health Science Center at New Orleans, USA
N Engl J Med 343:100-5. 2000..We performed a study to develop and validate a set of clinical criteria that could be used to identify patients with minor head injury who do not need to undergo CT...
- S100-B protein as a screening tool for the early assessment of minor head injuryDrissa Zongo
Service des urgences adultes, Hopital Pellegrin, Bordeaux, France
Ann Emerg Med 59:209-18. 2012..We evaluate S100-B protein measurement as a screening tool in a large population of patients with minor head injury...
- Concussion in professional football: reconstruction of game impacts and injuriesElliot J Pellman
ProHEALTH Care Associates, LLP, Lake Success, New York, USA
Neurosurgery 53:799-812; discussion 812-4. 2003..Concussion in professional football was studied with respect to impact types and injury biomechanics. A combination of video surveillance and laboratory reconstruction of game impacts was used to evaluate concussion biomechanics...
- The Canadian CT Head Rule for patients with minor head injuryI G Stiell
Divisions of Emergency Medicine, University of British Columbia, Vancouver, Canada
Lancet 357:1391-6. 2001..There is much controversy about the use of computed tomography (CT) for patients with minor head injury. We aimed to develop a highly sensitive clinical decision rule for use of CT in patients with minor head injuries...
- Publication bias and time-trend bias in meta-analysis of bicycle helmet efficacy: a re-analysis of Attewell, Glase and McFadden, 2001Rune Elvik
Institute of Transport Economics, Gaustadalleen 21, NO 0349 Oslo, Norway
Accid Anal Prev 43:1245-51. 2011..The re-analysis shows smaller safety benefits associated with the use of bicycle helmets than the original study...
- The potential of melatonin in reducing morbidity-mortality after craniocerebral traumaM D Maldonado
Department of Cellular and Structural Biology, University of Texas Health Science Center, San Antonio, TX, USA, and Center for Rehabilitation and Traumatology of the Hospital University Virgen del Rocio, Seville, Spain
J Pineal Res 42:1-11. 2007b>Craniocerebral trauma (CCT) is the most frequent cause of morbidity-mortality as a result of an accident...
- Comparison of the Canadian CT Head Rule and the New Orleans Criteria in patients with minor head injuryIan G Stiell
Department of Emergency Medicine, University of Ottawa, Ottawa, Ontario, Canada
JAMA 294:1511-8. 2005..However, uncertainty about the clinical performance of these rules exists...
- Neurochemical aftermath of amateur boxingHenrik Zetterberg
Department of Experimental Neuroscience, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
Arch Neurol 63:1277-80. 2006..Little solid information is available on the possible risks for neuronal injury in amateur boxing...
- Implementation of the Canadian C-Spine Rule: prospective 12 centre cluster randomised trialIan G Stiell
Department of Emergency Medicine, University of Ottawa, Canada
BMJ 339:b4146. 2009..To evaluate the effectiveness of an active strategy to implement the validated Canadian C-Spine Rule into multiple emergency departments...
- Impact of mandatory helmet legislation on bicycle-related head injuries in children: a population-based studyAlison K Macpherson
Division of Paediatric Medicine, Hospital for Sick Children, Toronto, Ontario, Canada
Pediatrics 110:e60. 2002..In Canada, 4 provinces have such legislation. The objective of this study was to measure the impact of helmet legislation on bicycle-related head injuries in Canadian children...
- Can the initial history predict whether a child with a head injury has been abused?Joeli Hettler
Division of Emergency Medicine, Children s Hospital, Boston, Harvard Medical School, Boston, MA 02115, USA
Pediatrics 111:602-7. 2003..The objective of this study was to determine the diagnostic utility of certain historical features for identifying cases of abusive head trauma...
- Incidence and demography of non-accidental head injury in southeast Scotland from a national databaseRobert A Minns
Department of Child Life and Health, University of Edinburgh, Edinburgh, Scotland, United Kingdom
Am J Prev Med 34:S126-33. 2008....
- The effects of provincial bicycle helmet legislation on helmet use and bicycle ridership in CanadaJessica Dennis
Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, Ontario, Canada
Inj Prev 16:219-24. 2010..The objectives of this study were to determine the association between the comprehensiveness of helmet legislation and both helmet use and bicycle ridership...
- Scandinavian guidelines for initial management of minimal, mild, and moderate head injuries. The Scandinavian Neurotrauma CommitteeT Ingebrigtsen
Norwegian Neurosurgical Society
J Trauma 48:760-6. 2000..The Scandinavian Neurotrauma Committee was initiated by the Scandinavian Neurosurgical Society to develop evidence-based guidelines for improved care of neurotrauma patients...
- Diagnostic management strategies for adults and children with minor head injury: a systematic review and an economic evaluationA Pandor
School of Health and Related Research ScHARR, University of Sheffield, Sheffield, UK
Health Technol Assess 15:1-202. 2011..Selective use of CT investigations helps minimise unnecessary radiation exposure and resource use, but can lead to missed opportunities to provide early treatment for ICI...
- Bicycle helmet efficacy: a meta-analysisR G Attewell
Covance Pty Ltd, Ainslie, ACT, Australia
Accid Anal Prev 33:345-52. 2001..Despite this, the use of helmets is sub-optimal. Helmet use for all riders should be further encouraged to the extent that it is uniformly accepted and analogous to the use of seat belts by motor vehicle occupants...
- Disaster epidemiology and medical response in the Chi-Chi earthquake in TaiwanN J Liang
Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan
Ann Emerg Med 38:549-55. 2001..Epidemiologic analysis can guide disaster response and preparation...
- Pattern of maxillofacial and associated injuries in road traffic accidentsM K Akama
Department of Oral and Maxillofacial Surgery, School of Dental Sciences, University of Nairobi, P O Box 19676 00202, Nairobi, Kenya
East Afr Med J 84:287-95. 2007..In an attempt to reduce RTAs, the government of Kenya has enacted a legislation requiring mandatory fitting of speed governors and safety belts by passenger service vehicles...
- Effects of head and extracranial injuries on serum protein S100B levels in trauma patientsOlli Savola
Department of Neurology, Oulu University Hospital, Oulu, Finland
J Trauma 56:1229-34; discussion 1234. 2004..Serum protein S100B determinations have been recently suggested as markers of traumatic brain injury. However, little is known about the effects of extracranial injuries on S100B levels in trauma patients...
- A prospective cluster-randomized trial to implement the Canadian CT Head Rule in emergency departmentsIan G Stiell
Department of Emergency Medicine, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Ont
CMAJ 182:1527-32. 2010..We sought to evaluate the effectiveness of implementing this validated decision rule at multiple emergency departments...
- Impact of early intervention on outcome following mild head injury in adultsJ Ponsford
Monash Epworth Rehabilitation Research Centre, Epworth Hospital, Richmond, Victoria, Australia
J Neurol Neurosurg Psychiatry 73:330-2. 2002..The impact of mild head injury is variable and determinants of outcome remain poorly understood. Results of previous intervention studies have been mixed...
- Indications for computed tomography in patients with mild head injuryKenichiro Ono
Department of Neurosurgery, Japan Self Defense Forces Central Hospital, Tokyo
Neurol Med Chir (Tokyo) 47:291-7; discussion 297-8. 2007..These indications for CT including JCS may be useful in the management of patients with mild head injury...
- Serum S-100B concentration provides additional information fot the indication of computed tomography in patients after minor head injury: a prospective multicenter studyPeter Biberthaler
Chirurgische Klinik und Poliklinik Innenstadt, Ludwig Maximilians Universitat Munchen, Nussbaumstrasse 20, 80336 Munchen, Germany
Shock 25:446-53. 2006..A prospective study of the clinical value of S-100B measurement in such patients is now under way...
- Reducing regional inequality in mortality from road traffic injuries through enforcement of the mandatory motorcycle helmet law in TaiwanTsung Hsueh Lu
NCKU Research Center for Health Data and Institute of Public Health, College of Medicine, National Cheng Kung University, Tainan, Taiwan
Inj Prev 18:150-7. 2012..This study was conducted to examine whether passage of the mandatory motorcycle helmet law in 1997 reduced the regional inequality in mortality from road traffic injuries (RTIs) across 22 cities/counties in Taiwan...
- Adult respiratory distress syndrome: a complication of induced hypertension after severe head injuryC F Contant
Department of Neurosurgery, Baylor College of Medicine, Houston, Texas 77030, USA
J Neurosurg 95:560-8. 2001....
- The impact of compulsory cycle helmet legislation on cyclist head injuries in New South Wales, AustraliaScott R Walter
NSW Injury Risk Management Research Centre, University of New South Wales, Sydney, Australia
Accid Anal Prev 43:2064-71. 2011..Despite numerous data limitations, we identified evidence of a positive effect of compulsory cycle helmet legislation on cyclist head injuries at a population level such that repealing the law cannot be justified...
- Diagnostic criteria and the use of ICD-10 codes to define and classify minor head injuryJ Bellner
Department of Neurosurgery, Lund University Hospital, Lund, Sweden
J Neurol Neurosurg Psychiatry 74:351-2. 2003..Epidemiological research on the incidence of traumatic head injuries relies on the correct definition and classification of the injury...
- Post-traumatic cerebral infarction. Neuroimaging findings, etiology and outcomeA Server
Department of Neuroradiology, Division of Radiology, , Oslo, Norway
Acta Radiol 42:254-60. 2001..The overall death rate was 43.8% and this result suggests that PTCI is an indication of a poor clinical outcome, especially among patients with associated subdural hematoma, brain swelling/edema and tSAH...
- The cost-effectiveness of diagnostic management strategies for adults with minor head injuryM W Holmes
School of Health and Related Research, The University of Sheffield, United Kingdom
Injury 43:1423-31. 2012..To estimate the cost-effectiveness of diagnostic management strategies for adults with minor head injury...
- Head impact exposure in youth footballRay W Daniel
Center for Injury Biomechanics, Virginia Tech Wake Forest University, 440 ICTAS Building, Stanger St, Blacksburg, VA 24061, USA
Ann Biomed Eng 40:976-81. 2012..In order to minimize these most severe head impacts, youth football practices should be modified to eliminate high impact drills that do not replicate the game situations...
- Bicycle helmet wearing and the risk of head, face, and neck injury: a French case--control study based on a road trauma registryEmmanuelle Amoros
Transport, Occupational and Environmental Epidemiology Research and Surveillance Unit UMRESTTE, French Institute of Science and Technology for Transport, Development and Networks IFSTTAR, Lyon Bron, France
Inj Prev 18:27-32. 2012..Previous case-control studies on bicycle helmet efficacy are mostly Anglo-Saxon, and based on data from the early 1990s when hard-shell helmets were common...
- Bicycle safety helmet legislation and bicycle-related non-fatal injuries in CaliforniaBrian Ho Yin Lee
Department of Urban Design and Planning, College of Architecture and Urban Planning, University of Washington, 3949 15th Avenue N E, 410 Gould Hall, Box 355740, Seattle, WA 98195 5740, USA
Accid Anal Prev 37:93-102. 2005....
- Can social psychological models be used to promote bicycle helmet use among teenagers? A comparison of the Health Belief Model, Theory of Planned Behavior and the Locus of ControlTimo Lajunen
Department of Psychology, Middle East Technical University, ODTU 06531, Ankara, Turkey
J Safety Res 35:115-23. 2004..Attitudes, personality and behavior. Open University Press, Milton Keynes) and Locus of Control model (LC; Psychological Monographs, (1966) (80) in understanding the intention to use bicycle helmet use among bicycle helmet owners...
- Emergency head injury imaging: implementing NICE 2007 in a tertiary neurosciences centre and a busy district general hospitalJ S Mooney
Salford Royal Foundation NHS Trust, Emergency Department, Salford, UK
Emerg Med J 28:778-82. 2011..Head injuries are a common emergency department (ED) presentation. The National Institute for Health and Clinical Excellence (NICE) updated its guidance in September 2007 regarding imaging required for patients with head injuries...
- Barriers to bicycle helmet use among Dutch paediatriciansE Villamor
Department of Pediatrics, Research Institute Growth and Development, Maastricht University Medical Centre, Maastricht, The Netherlands
Child Care Health Dev 34:743-7. 2008..We aimed to determine why Dutch paediatricians do or do not wear helmets while bicycling and whether their personal behaviour is influencing their position about the promotion of helmet use...
- External validation of the Canadian CT Head Rule and the New Orleans Criteria for CT scanning in patients with minor head injuryMarion Smits
Department of Radiology, Erasmus MC University Medical Centre, Rotterdam, The Netherlands
JAMA 294:1519-25. 2005....
- S100B serum level predicts computed tomography findings after minor head injuryKay Müller
Department of Neurosurgery, University Hospital of North Norway, Tromsø, Norway
J Trauma 62:1452-6. 2007..The present multicenter study was performed to investigate whether determination of protein S100B in serum could contribute to the selection of patients for CT scanning...
- Consequences of head size following trauma to the human headSvein Kleiven
Department of Aeronautics, Royal Institute of Technology, Teknikringen, 8 100 44 Stockholm, Sweden
J Biomech 35:153-60. 2002..The conclusion is that the size dependence of the intracranial stresses associated with injury, is not predicted by the HIC. It is suggested that variations in head size should be considered when developing new head injury criteria...
- Environmental risk factors for Parkinson's disease and parkinsonism: the Geoparkinson studyF D Dick
Dr F Dick, Department of Environmental and Occupational Medicine, Aberdeen University Medical School, Foresterhill, Aberdeen AB25 2ZP, UK
Occup Environ Med 64:666-72. 2007..To investigate the associations between Parkinson's disease and other degenerative parkinsonian syndromes and environmental factors in five European countries...
- Subdural haematoma and effusion in infancy: an epidemiological studyC Hobbs
Community Paediatrics, St James s University Hospital, Leeds, UK
Arch Dis Child 90:952-5. 2005..To determine incidence, aetiology, and clinical features of subdural haematoma and effusion (SDH/E) in infancy throughout the British Isles...
- Neck injuries in young pediatric homicide victimsLaura K Brennan
Division of General Pediatrics, The Children s Hospital of Philadelphia, Pennsylvania 19104, USA
J Neurosurg Pediatr 3:232-9. 2009....
- Shaken baby syndrome in Switzerland: results of a prospective follow-up study, 2002-2007Manuela Fanconi
Child Protection Group, University Children s Hospital Zurich, Steinwiesstrasse 75, 8032, Zurich, Switzerland
Eur J Pediatr 169:1023-8. 2010..Demographic characteristics and outcomes of Swiss patients were comparable to published studies...
- A review of risk factors and patterns of motorcycle injuriesMau Roung Lin
Institute of Injury Prevention and Control, Taipei Medical University, 250 Wu Hsing Street, Taipei 110, Taiwan, ROC
Accid Anal Prev 41:710-22. 2009..Features of motorcycle use and potentially effective prevention programs for motorcycle crash injuries in developing countries are discussed. Finally, recommendations for future motorcycle-injury research are made...
- Measuring acceptability of clinical decision rules: validation of the Ottawa acceptability of decision rules instrument (OADRI) in four countriesJamie C Brehaut
Department of Epidemiology and Community Medicine, University of Ottawa, Ottawa, ON, Canada
Med Decis Making 30:398-408. 2010..No existing instrument measures the acceptability of a rule. The current study validated such an instrument...
- Analysis of missed cases of abusive head traumaC Jenny
Department of Pediatrics, Brown University School of Medicine, Providence, RI, USA
JAMA 281:621-6. 1999..Abusive head trauma (AHT) is a dangerous form of child abuse that can be difficult to diagnose in young children...
- Minor head injury: guidelines for the use of CT--a multicenter validation studyMarion Smits
Department of Radiology, Erasmus MC University Medical Center Rotterdam, The Netherlands
Radiology 245:831-8. 2007..To prospectively and externally validate published national and international guidelines for the indications of computed tomography (CT) in patients with a minor head injury...
- Subsequent development of thrombocytopenia and coagulopathy in moderate and severe head injury: support for serial laboratory examinationMatthew M Carrick
Michel E DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA
J Trauma 58:725-9; discussion 729-30. 2005..This study assessed the development of thrombocytopenia and coagulopathy at admission and within the subsequent 72 hours after TBI...
- Raised serum S100B levels after acute bone fractures without cerebral injuryJohan Undén
Department of Neurosurgery, Lund University Hospital, Lund, Sweden
J Trauma 58:59-61. 2005..However, the cerebral specificity of S100B has been questioned. This study aims to show serum S100B levels after uncomplicated bone fractures in patients without current or prior neurologic diseases...
- Coagulopathy as a parameter to predict the outcome in head injury patients--analysis of 61 casesJinn Rung Kuo
Department of Neurosurgery, Chi Mei Medical Center, Yung Kang City, Tainan, Taiwan
J Clin Neurosci 11:710-4. 2004..We conclude that: (1) Coagulation state in head injury patients within 24 h after injury is of value in determining the outcome. (2) Coagulopathy score > or = 4 is a good predictor to evaluate mortality rate of head injury patients...
- Bicycle-related injuries among children and adolescents in the United StatesTracy J Mehan
Center for Injury Research and Policy, The Research Institute at Nationwide Children s Hospital, The Ohio State University, Columbus, OH, 43205, USA
Clin Pediatr (Phila) 48:166-73. 2009..77) times more likely to have their injuries result in death. The large number of annual bicycle related-injuries is evidence that prevention of these injuries should remain an important area of bicycle safety research and practice...
- Epidural hematoma in infants: a different entity?L Beni-Adani
Department of Neurosurgery, Hadassah University Hospital, Ein Karem, Jerusalem, Israel
J Trauma 46:306-11. 1999..Because there are no optimal prognostic tools or clear guidelines to perform computed tomography in this unique population, a new approach of neurotrauma scoring is suggested...
- Identification of children at very low risk of clinically-important brain injuries after head trauma: a prospective cohort studyNathan Kuppermann
Department of Emergency Medicine, University of California, Davis School of Medicine, Davis, CA, USA
Lancet 374:1160-70. 2009..CT imaging of head-injured children has risks of radiation-induced malignancy. Our aim was to identify children at very low risk of clinically-important traumatic brain injuries (ciTBI) for whom CT might be unnecessary...
- Effect of alcohol on Glasgow Coma Scale in head-injured patientsLance Stuke
Department of Surgery, Division of Burns, Trauma and Surgical Critical Care, University of Texas Southwestern Medical School, Dallas, TX 75390 9158, USA
Ann Surg 245:651-5. 2007..The purpose of this study was to test the hypothesis that the presence of blood alcohol has a clinically significant impact on GCS in TBI patients...
- Severe traumatic head injury affects systemic cytokine expressionDamien J LaPar
Division of Trauma and Surgical Critical Care, Department of Surgery, University of Virginia, Charlottesville, VA 22903, USA
J Am Coll Surg 214:478-86; discussion 486-8. 2012..This study aimed to characterize systemic cytokine profiles among traumatically injured patients to assess the effect of traumatic head injury on the systemic inflammatory response...
- Secondary intracranial hemorrhage after mild head injury in patients with low-dose acetylsalicylate acid prophylaxisMark Tauber
Department of Traumatology and Sports Injuries, University Hospital of Salzburg, Salzburg, Austria
J Trauma 67:521-5; discussion 525. 2009..In the literature, there is no evidence concerning the incidence of secondary intracranial hemorrhagic events (SIHE) in patients with LDA prophylaxis that had negative primary computed tomography (CT)-scan of the head...
- Intractable epilepsy and craniocerebral trauma: analysis of 163 patients with blunt and penetrating head injuries sustained in warHadi Kazemi
Shefa Neuroscience Research Center, Tehran, Iran
Injury 43:2132-5. 2012..Patients with military brain injury carry a high risk of intractable post-traumatic epilepsy decades after their injury, and thus require a long-term medical follow-up...
- Validation of a wireless head acceleration measurement system for use in soccer playERIN HANLON
Bioengineering Center, College of Engineering, Wayne State University, Detroit, MI, USA
J Appl Biomech 26:424-31. 2010..96 ± 0.02 for head to head forehead impacts. The systems showed a strong relationship when comparing RMS error, linear head acceleration, angular head acceleration, and the cross correlation values...
- Mild head injury - mortality and complication rate: meta-analysis of findings in a systematic literature reviewJ L Af Geijerstam
The Swedish Council on Technology Assessment in Health Care SBU, Stockholm, Sweden
Acta Neurochir (Wien) 145:843-50; discussion 850. 2003..These have not been reliably summarised. The study aims to estimate as accurately as possible the mortality, the complication rates, and the frequency of pathological findings on CT in patients with mild head injury...
- A nationwide review of the associations among cervical spine injuries, head injuries, and facial fracturesRyan Patrick Mulligan
Divisions of Neurosurgery and Plastic Surgery, Texas A and M Health Science Center and Scott and White, Temple, Texas, USA
J Trauma 68:587-92. 2010..The purpose of this study was to review the incidence of facial fractures, c-spine injuries, and head injuries at trauma centers across the United States...
- Pediatric crushing head injury: biomechanics and clinical features of an uncommon type of craniocerebral traumaAntonio López López-Guerrero
Unit of Pediatric Neurosurgery and Regional Service of Neurosurgery, Virgen de Arrixaca University Hospital, 30120 El Palmar, Murcia, Spain
Childs Nerv Syst 28:2033-40. 2012..However, a special type of head injury occurs when the children sustain a traumatism whose main component is a static load in relation to a crushing mechanism with the head relatively immobile...
- Predicting intracranial lesions by antiplatelet agents in subjects with mild head injuryAndrea Fabbri
Dipartimento dell Emergenza, Presidio Ospedaliero Morgagni Pierantoni, Azienda USL Forlì, Via Forlanini 34, I 47100 Forlì, Italy
J Neurol Neurosurg Psychiatry 81:1275-9. 2010..The effect of pre-injury antiplatelet treatment in the risk of intracranial lesions in subjects after mild head injury (Glasgow Coma Scale (GCS) 14-15) is uncertain...
- Emotional and cognitive consequences of head injury in relation to the glasgow outcome scaleJ T Wilson
Department of Psychology, University of Stirling, Stirling FK9 4LA, UK
J Neurol Neurosurg Psychiatry 69:204-9. 2000..The aims of the study were to investigate aspects of the validity of structured interviews for the GOS, and address the issue of the relation between the GOS and subjective reports of health outcome...
- Mortality prediction of head Abbreviated Injury Score and Glasgow Coma Scale: analysis of 7,764 head injuriesDemetrios Demetriades
Division of Trauma and SICU, Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
J Am Coll Surg 199:216-22. 2004..We assessed the prognostic value and limitations of Glasgow Coma Scale (GCS) and head Abbreviated Injury Score (AIS) and correlated head AIS with GCS...
- The Canadian CT Head Rule Study for patients with minor head injury: rationale, objectives, and methodology for phase I (derivation)I G Stiell
Ottawa Hospital Research Institute, 1053 Carling Avenue, Ottawa, Ontario, Canada K1Y 4E9
Ann Emerg Med 38:160-9. 2001..The Canadian CT Head Rule Study for patients with minor head injury: rationale, objectives, and methodology for phase I (derivation). Ann Emerg Med. August 2001;38:160-169.]..
- Trends in helmet use and head injuries in San Diego County: the effect of bicycle helmet legislationMing Ji
Division of Epidemiology and Biostatistics, Graduate School of Public Health, San Diego State University, 5500 Campanile Drive, San Diego, CA 92182 4162, USA
Accid Anal Prev 38:128-34. 2006..Probably due to several of its limitations, the current study did not confirm that helmet legislation alone significantly reduced head injury rates in San Diego County during the study period...
- Effect of mouthguards on head responses and mandible forces in football helmet impactsDavid C Viano
ProBiomechanics LLC, 265 Warrington Rd, Bloomfield Hills, MI 48304 2952, USA
Ann Biomed Eng 40:47-69. 2012..8-63.9%. Mouthguards tested in this study with the Hybrid III articulating mandible lowered forces on the dentition and TMJ, but generally did not influence HIC or concussion risks...
- Intracranial effects of endotracheal suctioning in the acute phase of head injuryMarco Gemma
University of Milano, Institute of Anesthesiology and Intensive Care, Neurointensive Care Unit, IRCCS San Raffaele Hospital, Milano, Italy
J Neurosurg Anesthesiol 14:50-4. 2002..In the case of patients with head injuries who coughed or moved during endotracheal suctioning, we strongly suggest deepening the level of sedation before completing the procedure to reduce the risk of adverse effects...
- [Influence of the respiratory physiotherapy on intracranial pressure in severe head trauma patients]Rosana A Thiesen
Unidade de Terapia Intensiva, Hospital das Clinicas, Universidade Estadual de Campinas, Campinas, SP, Brazil
Arq Neuropsiquiatr 63:110-3. 2005..To evaluate influence of the respiratory physiotherapy on intracranial pressure (ICP) in patients with severe head trauma...
- Performance of the Canadian CT Head Rule and the New Orleans Criteria for predicting any traumatic intracranial injury on computed tomography in a United States Level I trauma centerLinda Papa
Department of Emergency Medicine, Orlando Regional Medical Center, Orlando, FL, USA
Acad Emerg Med 19:2-10. 2012..Additionally, the performance of the CCHR was assessed in a larger cohort of those presenting with GCS of 13 to 15...
- Endotracheal lidocaine in preventing endotracheal suctioning-induced changes in cerebral hemodynamics in patients with severe head traumaFederico Bilotta
Department of Anesthesiology, Intensive Care and Pain Medicine, University of Rome La Sapienza, Viale Somalia, 81, Rome, 00199, Italy
Neurocrit Care 8:241-6. 2008....
- Abusive head trauma during a time of increased unemployment: a multicenter analysisRachel P Berger
Department of Pediatrics, Children s Hospital of Pittsburgh of UPMC, Pittsburgh, Pennsylvania 15224, USA
Pediatrics 128:637-43. 2011..To evaluate the rate of abusive head trauma (AHT) in 3 regions of the United States before and during an economic recession and assess whether there is a relationship between the rate of AHT and county-level unemployment rates...
- Posttraumatic cerebral infarction in patients with moderate or severe head traumaR Marino
Institute of Anesthesiology Intensive Care, University of Brescia, Brescia, Italy
Neurology 67:1165-71. 2006..To evaluate the frequency, types, and location of posttraumatic cerebral infarction, to assess if secondary cerebral insults were associated with cerebral infarction, and to determine if cerebral infarction affected patients' outcome...
- Motor vehicle injuries in childhood: a hospital-based study in Saudi ArabiaStanley J Crankson
Division of Pediatric Surgery, Department of Surgery, King Abdulaziz Medical City Riyadh, King Fahad National Guard Hospital, P O Box 22490, Riyadh 11426, Kingdom of Saudi Arabia
Pediatr Surg Int 22:641-5. 2006..Head trauma is the most common cause of morbidity and mortality. This study suggests that nationwide programs should target the use of seatbelts and helmets, and dangerous driving practices...
- Effectiveness of bicycle helmet legislation to increase helmet use: a systematic reviewM Karkhaneh
Department of Public Health Sciences, University of Alberta, Edmonton, Canada
Inj Prev 12:76-82. 2006..Helmet legislation has been proposed as a method to increase helmet wearing; while this social intervention is thought to be effective, no systematic review has been performed...
- Estimating the probability of abusive head trauma: a pooled analysisSabine Ann Maguire
Department of Child Health, School of Medicine, Cardiff University, Cardiff, United Kingdom
Pediatrics 128:e550-64. 2011..To determine which combinations of clinical features assist in distinguishing abusive head trauma (AHT) from nonabusive head trauma...
- Developing a decision instrument to guide computed tomographic imaging of blunt head injury patientsWilliam R Mower
UCLA Emergency Medicine Center, UCLA School of Medicine, Los Angeles, CA 90024, USA
J Trauma 59:954-9. 2005..Clinical characteristics may be able reliably identify patients who do not have intracranial injuries and consequently, do no require imaging...
- Chronic tinnitus resulting from head or neck injuriesRobert L Folmer
Department of Otolaryngology, Oregon Hearing Research Center, Oregon Health Science University Tinnitus Clinic, Portland, 97239, USA
Laryngoscope 113:821-7. 2003....
- Effect of legislation on the use of bicycle helmetsJohn C LeBlanc
Department of Pediatrics, Dalhousie University, Halifax, NS
CMAJ 166:592-5. 2002..We measured compliance before, during and after 1997, when legislation making the use of helmets mandatory for cyclists was enacted in Nova Scotia...
- Arguments against helmet legislation are flawedBrent Hagel
Montreal Children s Hospital Research Institute, Montreal, Canada
BMJ 332:725-6. 2006
- Management of severe head injury: institutional variations in care and effect on outcomeEileen M Bulger
Department of Surgery, University of Washington, Seattle, WA, USA
Crit Care Med 30:1870-6. 2002....
- Mild head injury: reliability of early computed tomographic findings in triage for admissionJ L Af Geijerstam
The Swedish Council on Technology Assessment in Health Care SBU and the Department of Medicine, Clinical Epidemiology Unit, Karolinska University Hospital, Stockholm, Sweden
Emerg Med J 22:103-7. 2005..To search the literature for case reports on adverse outcomes in patients with mild head injury where acute computed tomography (CT) findings had been normal...
- Immediate and delayed traumatic intracranial hemorrhage in patients with head trauma and preinjury warfarin or clopidogrel useDaniel K Nishijima
Department of Emergency Medicine, UC Davis School of Medicine, Sacramento, CA, USA
Ann Emerg Med 59:460-8.e1-7. 2012..The objective of this study is to address these gaps in knowledge...
- Pediatric neurotrauma in Kathmandu, Nepal: implications for injury management and controlKarim Mukhida
Division of Neurosurgery, University of Toronto, Toronto, Canada
Childs Nerv Syst 22:352-62. 2006..The epidemiology of acute pediatric neurotrauma in Kathmandu was studied to assess the implications of these data for injury prevention programs...
- Implementation of a guideline for computed tomography head imaging in head injury: a prospective studyChristina Fong
Monash Medical Centre, Southernhealth Care, Clayton, Victoria, Australia
Emerg Med Australas 20:410-9. 2008..To improve appropriate ordering of head computed tomography (CT) in patients presenting with a head injury by applying an evidence-based head injury guideline...
- Apolipoprotein E modifies the CNS response to injury via a histamine-mediated pathwayBrian E Mace
Department of Medicine Neurology, Duke University Medical Center, Durham, NC 27710, USA
Neurol Res 29:243-50. 2007..These results suggest that apoE modifies secondary neuronal injury caused by histamine release and are consistent with previous observations that apoE affects the CNS inflammatory response in an isoform-specific manner...
- Assessment, investigation, and early management of head injury: summary of NICE guidanceDavid Yates
Trauma Audit and Research Network TARN, Manchester M6 8HD
BMJ 335:719-20. 2007
- An observational study of compliance with the Scandinavian guidelines for management of minimal, mild and moderate head injuryBen Heskestad
Department of Neurosurgery, Oslo University Hospital Ulleval, Oslo, Norway
Scand J Trauma Resusc Emerg Med 20:32. 2012..The aim of the present study was to investigate guideline compliance after an educational intervention...
- Reasons for ordering computed tomography scans of the head in patients with minor brain injuryMartin Rohacek
Department of Emergency Medicine, Inselspital, University Hospital Bern, Bern, Switzerland
Injury 43:1415-8. 2012..We hypothesized that institutional guidelines are not frequently used, and that psychological factors are a common reason for ordering an unnecessary CT...
- A decrease in both mild and severe bicycle-related head injuries in helmet wearing ages--trend analyses in SwedenPeter Berg
Department of Public Health and Caring Sciences and Social Medicine, Uppsala Science Park, SE 751 85 Uppsala, Sweden
Health Promot Int 22:191-7. 2007..The increasing helmet use among younger schoolchildren probably contributed to the decrease in head injuries...
- Abusive head trauma at a tertiary care children's hospital in Mexico City. A preliminary studyClaudia Diaz-Olavarrieta
National Institute of Public Health, Research Center on Health Population, Mexico City, Mexico
Child Abuse Negl 35:915-23. 2011....
- Alcohol consumption, blood alcohol concentration level and guideline compliance in hospital referred patients with minimal, mild and moderate head injuriesMarianne Efskind Harr
Department of Neurosurgery, Oslo University Hospital Ulleval, Norway
Scand J Trauma Resusc Emerg Med 19:25. 2011....
- Canadian CT head rule study for patients with minor head injury: methodology for phase II (validation and economic analysis)I G Stiell
Ottawa Health Research Institute, Ottawa, Ontario, Canada
Ann Emerg Med 38:317-22. 2001..This will determine the clinical utility of the rule and is essential if such a rule is to be widely adopted into clinical practice...
- Scandinavian guidelines for initial management of minimal, mild and moderate head injuries in adults: an evidence and consensus-based updateJohan Undén
Department of Intensive Care and Perioperative Medicine, Institute for Clinical Sciences, Södra Förstadsgatan 101, 20502 Malmo, Sweden
BMC Med 11:50. 2013..In 2000, the Scandinavian Neurotrauma Committee (SNC) presented evidence-based guidelines for initial management of these injuries. Since then, considerable new evidence has emerged...
- Clinical decision rules for adults with minor head injury: a systematic reviewSue E Harnan
School of Health and Related Research, University of Sheffield, Sheffield, South Yorkshire, UK
J Trauma 71:245-51. 2011..This study aimed to systematically identify clinical decision rules for adults with minor head injury and compare the estimated diagnostic accuracies for any intracranial injury and injury requiring neurosurgical intervention...
- Head and traumatic brain injuries among Australian children, July 2000-June 2006Jesia G Berry
Research Centre for Injury Studies, Flinders University, Adelaide, South Australia, Australia
Inj Prev 16:198-202. 2010..To describe the rates of hospitalisation for head and traumatic brain injury among Australian children aged 0-14 years...
- Non-accidental head injury--the evidenceTimothy J David
Department of Child Health, Booth Hall Children s Hospital, University of Manchester, Blackley, Manchester, M9 7AA, UK
Pediatr Radiol 38:S370-7. 2008
- Cerebral perfusion pressure and risk of brain hypoxia in severe head injury: a prospective observational studyAntonio J Marín-Caballos
Servicio de Cuidados Criticos y Urgencias, Hospitales Universitarios Virgen del Rocio, Avda Manuel Siurot s n, Seville, 41013, Spain
Crit Care 9:R670-6. 2005..We study the distribution of hypoxic PtiO2 samples at different CPP thresholds, using prospective multimodality monitoring in patients with severe traumatic brain injury...
- Which clinical features distinguish inflicted from non-inflicted brain injury? A systematic reviewS Maguire
Child Health, School of Medicine, Cardiff University, Heath Park, Cardiff CF14 4XN, UK
Arch Dis Child 94:860-7. 2009..A systematic review of the scientific literature to define clinical indicators distinguishing inflicted (iBI) from non-inflicted brain injury (niBI)...
- Perfusion computed tomography in the acute phase of mild head injury: regional dysfunction and prognostic valueZwany Metting
Department of Neurology, University Medical Center Groningen, Groningen, The Netherlands
Ann Neurol 66:809-16. 2009..Furthermore, the relation between perfusion CT parameters and severity of head injury and outcome was evaluated...
- Paediatric trauma: injury pattern and mortality in the UKJ Bayreuther
Paediatric A E, Fulham Road, Chelsea and Westminster Hospital, London, UK
Arch Dis Child Educ Pract Ed 94:37-41. 2009..Trauma accounts for a large proportion of childhood deaths. No data exist about injury patterns within paediatric trauma in the UK. Identification of specific high-risk injury patterns may lead to improved care and outcome...
- A systematic review of the diagnostic accuracy of ocular signs in pediatric abusive head traumaGaurav Bhardwaj
Faculty of Medicine, University of New South Wales, Randwick, NSW, Australia
Ophthalmology 117:983-992.e17. 2010..To review systematically the diagnostic accuracy of various ocular signs for pediatric abusive head trauma (AHT)...
- Combination drug treatment to inhibit multiple cell death pathways after TBIALAN IRA FADEN; Fiscal Year: 2010..The Centers for Disease Control and Prevention (CDC) defines traumatic brain injury (TBI) as craniocerebral trauma associated with a decreased level of consciousness, amnesia, other neurologic or neuropsychological ..
- Emergency Neurophysiological Assessment Bedside Logic EngineDon M Tucker; Fiscal Year: 2010..Network access technology will facilitate remote review by expert neurologists, and a training protocol will provide first-responder usability for emergency technicians and physicians without training in clinical neurophysiology. ..
- PARP inhibitor and Redox Catalyst Conjugate for Traumatic Brain InjuryKanneganti Murthy; Fiscal Year: 2012..We are developing a novel drug that targets the basic mechanisms of this condition and will test this agent in a clinically-relevant animal model. ..
- Effect of Inducible Antioxidants on Hemoglobin ToxicityRaymond F Regan; Fiscal Year: 2010..The ultimate goal is to reduce brain injury in tissue surrounding a blood clot, and to thereby improve the likelihood of survival and return to an independent, productive life. ..
- Novel non-invasive device for treatment of elevated intracranial pressuresKeith G Lurie; Fiscal Year: 2011....
- Investigation of Zinc Neurochemistry by Optical Sensing and MRIStephen J Lippard; Fiscal Year: 2013..Uncontrolled zinc levels contribute to neurodegenerative diseases, which may be responsive to zinc-selective chelating agents also devised in the project. ..
- Clinical Decision Support for Mild Traumatic Brain InjuryEDWARD ROBERT MELNICK; Fiscal Year: 2013..The tool will include special provisions for shared decision- making with the elderly, another AHRQ priority population. ..
- Elevated Zinc in Ischemia and reperfusionYang V Li; Fiscal Year: 2013....
- Development and Validation of a Diagnostic Tool for Infant Head Injuries from FalSUSAN SHEPS contact MARGULIES; Fiscal Year: 2010....
- Predict Near Future Bed Exit for Effective Intervention to Avoid Nighttime FallsTHOMAS HENRY WHALEN; Fiscal Year: 2012..Therefore, with a rapidly aging population, ever-increasing healthcare costs, and limited healthcare resources, there is significant and critical relevance to reducing the number of falls, and fall-related injuries among the elderly. ..
- Identifying neurons and circuits critical for epileptogenesisIstvan Mody; Fiscal Year: 2013..The new discoveries will facilitate the translation of our basic findings into clinical practice. ..
- High School Student NeuroResearch Program (HSNRP)Marlys Hearst Witte; Fiscal Year: 2013..Ongoing short-term and long-term evaluation including surveys, database registry and career portfolios will document efficacy of the training model and promote networking. ..
- Neuropeptide Modulation of ASICsCandice C Askwith; Fiscal Year: 2012..ASIC1a represents an exciting new target for therapeutics to prevent brain injury and these studies will provide vital information to understand the fundamental mechanism of ASIC1a-induced neuronal death. ..
- Profiling human reactive astrocytes for neurotrauma biomarkersIna Beate Wanner; Fiscal Year: 2012....
- Group I Metabotropic Glutamate Receptors and EpileptogenesisPaul A Rutecki; Fiscal Year: 2013....
- Meningioma: Risk Factors and Quality of LifeMelissa L Bondy; Fiscal Year: 2010..This study represents the first concentrated effort to examine environmental and genetic risk factors for meningiomas. ..
- Meningioma: Risk Factors and Quality of LifeJoellen M Schildkraut; Fiscal Year: 2010..This study represents the first concentrated effort to examine environmental and genetic risk factors for meningioma. ..
- Meningioma: Risk Factors and Quality of LifePeter M Black; Fiscal Year: 2010..This study represents the first concentratedeffort to examine environmental and genetic risk factors for meningioma. ..
- Meningioma: Risk Factors and Quality of LifeElizabeth B Claus; Fiscal Year: 2010..This study represents the first concentrated effort to examine environmental and genetic risk factors for meningioma. ..
- Meningioma: Risk Factors and Quality of LifeJOSEPH LEO WIEMELS; Fiscal Year: 2010..This study represents the first concentrated effort to examine environmental and genetic risk factors for meningioma. ..
- Investigating the Role of Atg1 in the Regulation of Glutamate ReceptorsFaith Liebl; Fiscal Year: 2009..Determining the role of atg1 in glutamate receptor cluster formation by analyses of atg1 mutants will improve our understanding of both autophagy and the mechanisms that govern glutamate receptor expression and location. ..
- Summers in Childrens Research for Diverse High School StudentsMarlys Hearst Witte; Fiscal Year: 2013....
- TGF-beta Mediated Inflammatory Signaling: a Critical Role in EpileptogenesisDaniela Kaufer; Fiscal Year: 2012..Since brain insults are one of the primary causes of disability with no means of prevention as of yet, this proposal represents an important advancement toward resolving this unmet medical need. ..
- Viscoelastic Properties of Human Facial SkinMARK WILLIAM BEATTY; Fiscal Year: 2012..These objectives match those stated by RR&D as being key goals of this funding award. ..
- Canonical Transient Receptor Potential Channels and ExcitotoxicityFang Zheng; Fiscal Year: 2010..In addition, the signaling studies mentioned in the abstract have been deleted. All else has remained the same since the proposed experiments to remain in the grant address the original scope of the grant. ..
- p75NTR Ligands for Treament of Traumatic Brain InjuryStephen M Massa; Fiscal Year: 2013..The overall goal of this research is to advance the application of these neurotrophic compounds to the treatment of brain trauma and other conditions. ..
- Cognition in Parkinson's DiseaseDEBORAH LYNN HARRINGTON; Fiscal Year: 2013..This knowledge could promote more optimal, individualized treatments and drive the development of new medication treatments. ..
- Failure of metabolite clearance in a model of multi-lacunar infarctsMaiken Nedergaard; Fiscal Year: 2013..The proposed studies will provide fundamental new insight into cognitive impairment in vascular dementia, and will likely also improve our understanding of the pathophysiology of brain injury following stroke and head trauma. ..
- Ghrelin and Traumatic Brain InjuryRongqian Wu; Fiscal Year: 2012..The relevance of this proposal to public health is to eventually use ghrelin in the treatment of patients with head injury. ..
- High-resolution ex vivo micro-computerized tomography systemMary F Barbe; Fiscal Year: 2010..The acquisition of the SkyScan 1172 is essential for continued progress of these and future projects requiring this state-of-the-art technology. ..
- Dynamic Neuroimaging with High-resolution SSVEPsRamesh Srinivasan; Fiscal Year: 2012....
- CXCR4-Vagal Tone and Gastric motilityRichard C Rogers; Fiscal Year: 2013..Our hypothesis is that chemokines released as a function of the disease process directly affect the activity of cells in the brainstem that are responsible for essential digestion and feeding behavior control. ..
- Chronic Traumatic Encephalopathy: Clinical Presentation and BiomarkersRobert A Stern; Fiscal Year: 2013..abstract_text> ..
- Facilitating Advancement in the Social SciencesCARRIE L SAETERMOE; Fiscal Year: 2010....
- Calvarial periosteal afferents in post-traumatic headacheDan Levy; Fiscal Year: 2012..Data collected will lead to further testable hypotheses on the cellular and molecular changes that contribute to the development of PTH. ..
- High Performance, Low Cost PET ScintillatorsKanai S Shah; Fiscal Year: 2013..Construction and evaluation of detector modules for PET imaging based on optically transparent ceramic garnet scintillators is also planned in the proposed effort. ..
- Molecular mechanisms of adult neurogenesis following traumatic brain injuryMICHELLE LEE THEUS; Fiscal Year: 2010..Our ultimate goal is to devise novel experimental therapies to treat brain injury and improve recovery of function in patients who sustain head trauma using adult neural stem cells. ..
- Mouse genetic differences in exercise-induced hippocampal neurogenesis &learningJustin S Rhodes; Fiscal Year: 2013..PUBLIC HEALTH RELEVANCE: The goal of this project is to discover mechanisms for pro cognitive effects of exercise at multiple levels of biological organization from genes to physiology to behavior. ..
- HMGB1 and Traumatic Brain InjuryKrishnan M Dhandapani; Fiscal Year: 2013..The results of these studies may support the future development of novel therapeutics directed against this pathway to limit neurological injury following head trauma. ..
- Neuronal Loss and Plasticity in EpilepsyCarolyn R Houser; Fiscal Year: 2013..The broad goals of the studies are to identify progressive changes that could promote the development of epilepsy following status epilepticus or head trauma and thus provide a basis for designing treatments to prevent such changes. ..
- Goal-directed Resuscitative Interventions during Pediatric Inter-facility TranspoMICHAEL HUGH STROUD; Fiscal Year: 2011..This study has the potential to change the current practice of pediatric inter-facility transport, and improve clinical outcomes of pediatric SIRS. ..
- Racial Stereotypes and the Recognition of Child AbuseAntoinette L Laskey; Fiscal Year: 2010..Specific Aim 3 will be refinement and testing of this intervention and its effects on physicians'decision-making behavior in order to gather important data needed to develop a successful R01 application. ..
- Neural Interactions Among Multiple Motor StructuresMarc H Schieber; Fiscal Year: 2010..Such an improved understanding of the motor system can lead to improved rehabilitative treatment, and improved functional recovery after nervous system injury from diseases such as stroke and head trauma. ..
- NEUROBEHAVIORAL OUTCOME OF HEAD INJURY IN CHILDRENHarvey Levin; Fiscal Year: 2013..Head injuries can cause teenagers to have problems with their friends. This study tries to figure out why head injuries cause these social problems and may help find ways to treat young people with a head injury. ..
- MR spectroscopic imaging to detect the development of latent epilepsyJullie W Pan; Fiscal Year: 2013..This will be done in a blinded fashion. As all animals will also be video and EEG monitored, we will also be able to test the ability of the MRSI to identify those animals who go on to develop overt recurrent seizures. ..
- Contributions of aberrant granule cell integration to the development of epilepsySteve C Danzer; Fiscal Year: 2013..By determining how normal brains become epileptic, we can begin to develop therapies to delay, halt and ultimately reverse the process. ..
- Biological Inquiry into the Mechanisms and Neuroprotective Strategy for TBIDong Feng Chen; Fiscal Year: 2013..If the hypothesis is proven valid, an innovative technology that has strong implications for translation into clinical practice could be developed in the near future. ..
- Role of BACE in the pathogenesis of Alzheimer's disease after head traumaGiuseppina Tesco; Fiscal Year: 2013..abstract_text> ..
- NMDA Receptor Dynamics After Brain InjuryAnat Biegon; Fiscal Year: 2011..The results may explain the failure of NMDAR antagonists in clinical trials and suggest novel strategies for treatment of brain injury. ..
- Altered synaptogenesis after albumin exposure: A model for post traumatic epilepLydia J Wood; Fiscal Year: 2012..Furthermore, by dissociating different effects of albumin on the development of synaptic reorganization, I expect to identify possible targets for therapeutic prevention of posttraumatic epileptogenesis. ..
- Chronic TBI Bcl 2-20:34 Protection Against Lowered Seizure SusceptibilityRoi Ann Wallis; Fiscal Year: 2013..To this end, we will also evaluate mitochondrial structure and function after CCI with and without treatment with the Bcl-220-34 peptide. ..
- Field Triage of Head Injured Older Adults Taking Anticoagulants or Platelet InhibDANIEL KIDEN NISHIJIMA; Fiscal Year: 2013....
- Brain injury due to soccer heading and opportunities for its mitigationMICHAEL LAWRENCE LIPTON; Fiscal Year: 2013..Aim III (Intensive measurement): Determine the short-term effects on and variability in day-to-day cognitive function and PCS using an intensive measurement design. ..
- Factors Associated with Quality of Care Delivered to Children in US EDsJames P Marcin; Fiscal Year: 2012..abstract_text> ..
- High-Level Expression of Human EAAT3 for Biochemical and Structural AnalysisDIANNE LYNN DECAMP; Fiscal Year: 2011....
- Neuroplasticity-Based Technology for Executive Function Deficits in ConcussionBrian T Miller; Fiscal Year: 2013....
- 1/2 A Large-Scale Schizophrenia Association Study in SwedenPatrick F Sullivan; Fiscal Year: 2013..We propose to do this using the largest and most comprehensively studied sample collection in the field and which includes both genetic and environmental risk factors. ..
- Console Electronics Upgrade for 11.7T MRI SystemChien Ho; Fiscal Year: 2013..Overall, the proposed equipment upgrade is critical for maintaining the 11.7T instrument as a state-of-the-art system to support ongoing research for 5 Major and 12 Minor users. ..
- Long Term Outcomes in ICU Patients: Delirium & Apolipoprotein ESheila Alexander; Fiscal Year: 2009..This would likely lead to decreased time in the ICU and hospital. ..
- Effectiveness of bicycle helmet laws in preventing injuries among youthPinka Chatterji; Fiscal Year: 2010..The results from this study will provide policymakers with new, important information not only about the effectiveness of existing helmet laws, but also about how these laws can be designed to maximize their preventive benefits. ..
- The Epilepsy Phenome/ Genome Project (EPGP)Daniel H Lowenstein; Fiscal Year: 2013....
- Basic Mechanisms of the Epilepsies WorkshopsAntonio Delgado Escueta; Fiscal Year: 2009..5 million persons) and worldwide (50-100 million persons) and still there are no cures and treatments that put a dent in the stable prevalence and incident rates of the epilepsies. ..
- HYPOTHERMIA AND TRAUMALarry Jenkins; Fiscal Year: 2000....
- REGULATING CEREBROSPINAL FLUID FORMATIONBarry Hoffer; Fiscal Year: 1992..It is planned that promising animal studies will be followed up by clinical study proposals...
- NAAG Peptidase Inhibitors for the Treatment of Traumatic Brain InjuryJia Zhou; Fiscal Year: 2009....
- CHILD AND FAMILY FUNCTIONING AFTER PEDIATRIC HEAD TRAUMAJoAnne Youngblut; Fiscal Year: 2001..If nursing research and care can facilitate achieving these objectives, burden on health care, educational, and family systems will be reduced. ..
- APOLIPOPROTEIN E AND THE ISCHEMIC BRAINDavid Warner; Fiscal Year: 2001..We believe that this information would be of substantial value in defining both the relevance of Apo E mechanisms to ischemic outcome and provide a basis for therapeutic approaches to the treatment of stroke. ..
- BEHAVIORAL EFFECTS OF BRAIN INJURYSuzanne Corkin; Fiscal Year: 1990....
- MUSCARINIC RECEPTOR COUPLING TO INOSITIDES IN CNSStephen Fisher; Fiscal Year: 2006..Accordingly, knowledge of the signal transduction pathways that regulate VSOAC is an essential prerequisite for the rational design of therapeutic agents. ..
- Revitalizing Allografts for Craniofacial ReconstructionEdward Schwarz; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- PLASTICITY OF GABAERGIC INHIBITION FOLLOWING HEAD INJURYIvan Soltesz; Fiscal Year: 2001....