hypoglossal nerve diseases

Summary

Summary: Diseases of the twelfth cranial (hypoglossal) nerve or nuclei. The nuclei and fascicles of the nerve are located in the medulla, and the nerve exits the skull via the hypoglossal foramen and innervates the muscles of the tongue. Lower brain stem diseases, including ischemia and MOTOR NEURON DISEASES may affect the nuclei or nerve fascicles. The nerve may also be injured by diseases of the posterior fossa or skull base. Clinical manifestations include unilateral weakness of tongue musculature and lingual dysarthria, with deviation of the tongue towards the side of weakness upon attempted protrusion.

Top Publications

  1. ncbi Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-2002--a 35-year-old man with headache, deviation of the tongue, and unusual radiographic abnormalities
    William F C Rigby
    N Engl J Med 347:2057-65. 2002
  2. ncbi Dumbbell-shaped hypoglossal schwannoma in an elderly woman: a clinical dilemma
    Kouki Aihara
    Department of Neurosurgery, Faculty of Medicine, University of Tokyo, Tokyo 113 8655, Japan
    Surg Neurol 63:526-8; discussion 528. 2005
  3. ncbi "Triple cross" of the hypoglossal nerve and its microsurgical impact to entrapment disorders
    G Bademci
    Department of Neurosurgery, University of Kirikkale, Kirikkale, Turkey
    Minim Invasive Neurosurg 49:234-7. 2006
  4. doi Hypoglossal-vertebral entrapment syndrome
    Yasser Aladdin
    Division of Neurology, University of Alberta Hospital, 2E3 Walter McKenzie Center, 8440 112 St, Edmonton, Alberta, Canada
    Neurology 71:461. 2008
  5. ncbi [Hypoglossal neurilemmoma: current experience in diagnosis and treatment]
    Bai Chun Yang
    Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China
    Zhonghua Wai Ke Za Zhi 42:1384-8. 2004
  6. ncbi Occipital neuralgia and twelfth nerve palsy from a chondromyxoid fibroma
    Karen Kaye Bloom
    Department of Medicine, Division of Physical Medicine and Rehabilitation, University of Louisville School of Medicine, Louisville, KY, USA
    J Ky Med Assoc 102:255-8. 2004
  7. ncbi Extracranial hypoglossal schwannoma
    Annemarei Ranta
    Department of Neurology, University of Virginia Health Sciences Center, Charlottesville, USA
    Neurology 60:E11. 2003
  8. ncbi Dumbbell-shaped hypoglossal schwannoma. A case report
    Johanna Rachinger
    Institute of Radiology and Neuroradiology, Oberösterreichische Landesnervenklinik Wagner Jauregg, Linz, Austria
    Magn Reson Imaging 21:155-8. 2003
  9. ncbi Rare localization of paraganglioma in head and neck
    Toshiharu Shintani
    Department of Otolaryngology, St Marianna University School of Medicine, 2 16 1 Sugao, Miyamae ku, 216 8511, Kawasaki, Japan
    Auris Nasus Larynx 30:S149-52. 2003
  10. ncbi Delayed hypoglossal palsy following occipital condyle fracture--case report
    Natarajan Muthukumar
    Department of Neurosurgery, Madurai Medical College, Madurai, 625 020, Tamil Nadu, India
    J Clin Neurosci 9:580-2. 2002

Detail Information

Publications177 found, 100 shown here

  1. ncbi Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 39-2002--a 35-year-old man with headache, deviation of the tongue, and unusual radiographic abnormalities
    William F C Rigby
    N Engl J Med 347:2057-65. 2002
  2. ncbi Dumbbell-shaped hypoglossal schwannoma in an elderly woman: a clinical dilemma
    Kouki Aihara
    Department of Neurosurgery, Faculty of Medicine, University of Tokyo, Tokyo 113 8655, Japan
    Surg Neurol 63:526-8; discussion 528. 2005
  3. ncbi "Triple cross" of the hypoglossal nerve and its microsurgical impact to entrapment disorders
    G Bademci
    Department of Neurosurgery, University of Kirikkale, Kirikkale, Turkey
    Minim Invasive Neurosurg 49:234-7. 2006
    ..Cadaveric dissections were performed to review the intracranial and extracranial course of the hypoglossal nerve. The neurological significance of a newly defined "triple cross" of the hypoglossal nerve is discussed...
  4. doi Hypoglossal-vertebral entrapment syndrome
    Yasser Aladdin
    Division of Neurology, University of Alberta Hospital, 2E3 Walter McKenzie Center, 8440 112 St, Edmonton, Alberta, Canada
    Neurology 71:461. 2008
  5. ncbi [Hypoglossal neurilemmoma: current experience in diagnosis and treatment]
    Bai Chun Yang
    Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai 200040, China
    Zhonghua Wai Ke Za Zhi 42:1384-8. 2004
    ..To improve the diagnosis and treatment of hypoglossal neurilemmoma (HGN)...
  6. ncbi Occipital neuralgia and twelfth nerve palsy from a chondromyxoid fibroma
    Karen Kaye Bloom
    Department of Medicine, Division of Physical Medicine and Rehabilitation, University of Louisville School of Medicine, Louisville, KY, USA
    J Ky Med Assoc 102:255-8. 2004
    ..No similar case reports were found in the literature. In addition, the tumor was an unusual one, a chondromyxoid fibroma (CMF); these tumors uncommonly involve the skull base...
  7. ncbi Extracranial hypoglossal schwannoma
    Annemarei Ranta
    Department of Neurology, University of Virginia Health Sciences Center, Charlottesville, USA
    Neurology 60:E11. 2003
  8. ncbi Dumbbell-shaped hypoglossal schwannoma. A case report
    Johanna Rachinger
    Institute of Radiology and Neuroradiology, Oberösterreichische Landesnervenklinik Wagner Jauregg, Linz, Austria
    Magn Reson Imaging 21:155-8. 2003
    ..The tumor was excised by two-stage suboccipital osteoclastic craniotomy and later through a cervical approach. Pathohistology showed a grade I schwannoma and the patient was discharged symptom-free without any further therapy...
  9. ncbi Rare localization of paraganglioma in head and neck
    Toshiharu Shintani
    Department of Otolaryngology, St Marianna University School of Medicine, 2 16 1 Sugao, Miyamae ku, 216 8511, Kawasaki, Japan
    Auris Nasus Larynx 30:S149-52. 2003
    ..The intraoperative findings were highly suggestive of localization at the hypoglossal nerve, although Xth and XIIth cranial nerve palsies have remained...
  10. ncbi Delayed hypoglossal palsy following occipital condyle fracture--case report
    Natarajan Muthukumar
    Department of Neurosurgery, Madurai Medical College, Madurai, 625 020, Tamil Nadu, India
    J Clin Neurosci 9:580-2. 2002
    ..Since occipital condyle fractures can exist without neurological deficits, special attention should be paid to imaging of the craniovertebral junction in patients with head injury...
  11. ncbi Cranial nerve XII: the hypoglossal nerve
    Christopher Loh
    Department of Radiology, West Florida Hospital, Pensacola, USA
    Semin Ultrasound CT MR 23:256-65. 2002
    ..The following discussion of the evaluation of the hypoglossal nerve will involve the embryology, anatomy, clinical basis, and imaging techniques with pathologic correlations...
  12. ncbi Hypoglossal nerve paralysis following tonsillectomy
    C M Sharp
    Department of Otorhinolaryngology, Glasgow Royal Infirmary, UK
    J Laryngol Otol 116:389-91. 2002
    ..The likely causes of nerve injury are described and precautions are suggested to help avoid this problem...
  13. ncbi Navigated dorsolateral suboccipital transcondylar (NADOSTA) approach for treatment of hypoglossal schwannoma. Case report and review of the literature
    Chi Long Ho
    Department of Neurosurgery, Heilig Hart Teaching Hospital Ziekenhuis, Wilgenstraat 2, Roeselare 8800, Belgium
    Clin Neurol Neurosurg 107:236-42. 2005
    ..By introducing this minimally invasive dorsal surgical approach with neuronavigation in treating hypoglossal schwannoma, we believe that safe exposure and complete tumor resection can be achieved with minimal rate of morbidity...
  14. ncbi Dural arteriovenous fistula of the anterior condylar confluence and hypoglossal canal mimicking a jugular foramen tumor
    James K Liu
    Department of Neurological Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    J Neurosurg 109:335-40. 2008
    ..They should be included in the differential diagnosis of hypervascular jugular bulb lesions. The authors review the anatomy of the ACC and discuss the literature on DAVFs involving the hypoglossal canal...
  15. ncbi [Unilateral fatty degeneration of tongue seen in a case of Villaret syndrome]
    Mariko Yamashita
    Department of Neurology, Osaka City Juso Hospital
    Brain Nerve 59:634-5. 2007
  16. ncbi Altered expression of Smad family members in injured motor neurons of rat
    Noriko Okuyama
    Department of Anatomy and Neurobiology, Osaka City University, Graduate School of Medicine, 1 4 3 Asahimachi, Abenoku, Osaka 545 8585, Japan
    Brain Res 1132:36-41. 2007
    ..Immunohistochemistry and Western blotting analysis confirmed the alterations of Smad1, 2 and 4 in injured neurons. These results suggest that the Smad signaling may be important for nerve regeneration...
  17. ncbi Infectious mononucleosis and unilateral tongue writhing
    Andreas van Baalen
    Department of Neuropediatrics, University of Kiel, Schwanenweg 20, 24105 Kiel, Germany
    Neurology 66:1110. 2006
  18. ncbi Hypoglossal nerve paralysis caused by high cervical epidural abscess
    T Srivastava
    Department of Neurology, All India Institute of Medical Sciences, New Delhi, India
    Neurology 66:522. 2006
  19. ncbi Bilateral and unilateral internal carotid artery dissection causing isolated hypoglossal nerve palsy: a case report and review of the literature
    B Olzowy
    Klinik fur Hals, Nasen und Ohrenheilkunde, Ludwig Maximilians Universitat Munchen, Marchioninistr 15, 81377, Munich, Germany
    Eur Arch Otorhinolaryngol 263:390-3. 2006
    ..In one case, a bilateral dissection was encountered. The clinical presentation and multidisciplinary management are discussed and the literature reviewed...
  20. ncbi Bilateral hypoglossal schwannoma: a radiologic diagnosis
    Devrim Bektas
    Department of Otolaryngology, Medicine Faculty of Karadeniz Technical University Farabi Hospital, Trabzon, Turkey
    Kulak Burun Bogaz Ihtis Derg 12:45-7. 2004
    ..The size of the masses and the clinical manifestations remained unchanged during a two-year follow-up period...
  21. ncbi Occipital condyle syndrome
    David J Capobianco
    Department of Neurology, Mayo Clinic, Jacksonville, Fla 32224, USA
    Headache 42:142-6. 2002
    ..Review the clinical features of occipital condyle syndrome...
  22. ncbi [Arachnoid cyst with consecutive brain stem atrophy, hypoglossal nerve paresis and tongue atrophy]
    H Adams
    ,
    Pathologe 22:266-9. 2001
    ..This lesion did not seem to have any further effects onto clinical presentation. The patient died of a fulminant lung embolism and also presented an adenocarcinoma of the lung...
  23. ncbi [Diagnosis and treatment of hypoglossal neurinoma]
    G Jia
    Department of Neurosurgery, Tiantan Hospital, Beijing 100050, China
    Zhonghua Yi Xue Za Zhi 81:1264-5. 2001
    ..The most common initial symptom is atrophy of tongue muscle. Radical resection is the best choice of treatment. The extrem-far-lateral approach is the best approach for operation. The prognosis is inspiring after operation...
  24. ncbi [Neurinoma of the descending loop of the hypoglossal nerve. Report of a case]
    M A Morey Mas
    , Hospital Son Dureta, Palma de Mallorca
    An Otorrinolaringol Ibero Am 28:523-9. 2001
    ....
  25. ncbi Isolated hypoglossal nerve palsy due to skull base metastasis from breast cancer
    K Pavithran
    Department of Medical Oncology, Rajiv Gandhi Cancer Institute and Research Centre, New Delhi, India
    Australas Radiol 45:534-5. 2001
    ..Physical examination revealed an isolated left hypoglossal nerve paralysis. The MRI scan showed a mass lesion involving the left occipital condyle extending into hypoglossal canal...
  26. ncbi A multifocal neurinoma of the hypoglossal nerve with motor paralysis confirmed by electromyography
    T Ogawa
    Department of Oral Surgery, Fukui Medical University, Japan
    Int J Oral Maxillofac Surg 30:176-8. 2001
    ..An electromyographic (EMG) study revealed decreased muscle activity on the left side of the tongue muscle, indicating dysfunction of the hypoglossal nerve. EMG was useful for diagnosis...
  27. ncbi Hypoglossal neuropathy in hereditary neuropathy with liability to pressure palsy
    W Christopher Winter
    Department of Neurology, University of Virginia, Charlottesville, USA
    Neurology 61:1154-5. 2003
  28. ncbi Craniovertebral junction neoplasms in the pediatric population
    Arnold H Menezes
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 1824 JPP, Iowa City, IA 52242, USA
    Childs Nerv Syst 24:1173-86. 2008
    ..The incidence of tumors at the craniovertebral junction in the pediatric population is low. Because of the variable pathology and the rarity of these tumors, ideal therapies are only now being defined...
  29. ncbi Characteristics, diagnosis and treatment of hypoglossal canal dural arteriovenous fistula: report of nine cases
    Shinji Manabe
    Department of Neurosurgery, University of Tokushima, Tokushima, Japan
    Neuroradiology 50:715-21. 2008
    ..We report the characteristics, diagnosis and treatment of dural arteriovenous fistula (DAVF) of the hypoglossal canal in nine patients with this relatively rare vascular disorder...
  30. ncbi Radiation-related cranial nerve palsy in patients with nasopharyngeal carcinoma
    Yaoh Shiang Lin
    Department of Otolaryngology, Tri Service General Hospital, National Defense Medical Center, Taipei, Taiwan, Republic of China
    Cancer 95:404-9. 2002
    ..This article presents the authors' experience with radiotherapy-related cranial nerve palsy in patients with NPC...
  31. ncbi Unusual primary manifestations of multiple sclerosis
    Yesim Yetimalar
    Department of Neurology, Atatürk Trainingand Research Hospital, 35370, zmir, Turkey
    N Z Med J 121:47-59. 2008
    ..The aim of this study is to describe patients with unusual symptoms that were primary manifestations of multiple sclerosis (MS)...
  32. ncbi Minor neck trauma in chronic ankylosing spondylitis: a potentially fatal combination
    Margaret D Smith
    Section of Rheumatology, Department of Medicine, New York Medical College at Saint Vincent Catholic Medical Center, NY 10011, USA
    J Clin Rheumatol 13:81-4. 2007
    ..The specific combination of long-standing ankylosing spondylitis and minor trauma is one setting in which a clinician must be alerted. Early consideration of neck immobilization is emphasized...
  33. pmc Hypoglossal nerve injury as a complication of anterior surgery to the upper cervical spine
    D K Sengupta
    Centre for Spinal Studies and Surgery, University Hospital Nottingham, Queen s Medical Center, UK
    Eur Spine J 8:78-80. 1999
    ..It is concluded that hypoglossal nerve palsy following anterior cervical spine surgery is unlikely to recover spontaneously and it should be carefully identified...
  34. ncbi [A case of Möbius syndrome presenting with symptoms of severe infantile form of congenital muscular disorder]
    Yoshihiko Imamura
    Department of Child Neurology, National Center Hospital for Mental, Nervous and Muscular Disorders, National Center of Neurology and Psychiatry, Kodaira, Tokyo
    No To Hattatsu 39:59-62. 2007
    ....
  35. ncbi Isolated unilateral paralysis of the hypoglossal nerve after transoral intubation for general anesthesia
    Sung Jin Hong
    Department of Anesthesiology and Pain Medicine, Catholic University of Korea, Medical College, Seoul 150 010, Korea
    Dysphagia 24:354-6. 2009
    ..We present a case of postoperative unilateral hypoglossal nerve palsy after general anesthesia for laparoscopic cholecystectomy...
  36. pmc Surgical management of dural arteriovenous fistulas with transosseous arterial feeders involving the jugular bulb
    W Tirakotai
    Department of Neurosurgery, University Hospital Marburg, 35043 Marburg, Germany
    Neurosurg Rev 30:40-8; discussion 48-9. 2007
    ..This approach allows for complete obliteration of the connecting arterial feeders, and removal of bony structures containing pathological vessels...
  37. ncbi Massive lingual teratoma in a neonate
    S Hassan
    Department of Otorhinolaryngology Head and Neck Surgery, School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian 16150, Kelantan, Malaysia
    Singapore Med J 48:e212-4. 2007
    ..Histopathologically, it consisted of all three layers of embryonic elements with predominantly glial tissue. Postoperatively, the patient developed hypoglossal nerve palsy, and no recurrence was detected after four years...
  38. ncbi Asymmetric tongue muscle uptake of F-18 FDG: possible marker for cranial nerve XII paralysis
    Eric Davis
    Division of Nuclear Medicine, Radiology Department, Hartford Hospital and Jefferson X ray Group, University of Connecticut Health Center, Farmington, Connecticut 06030 2804, USA
    Clin Nucl Med 29:531-3. 2004
    ..Uptake was likely related to right hemiglossal muscle activity. This was made more apparent by decreased uptake on the opposite side of the tongue (up to the midline) as a result of left cranial nerve XII paralysis...
  39. ncbi Isolated Hypoglossal nerve palsy due to amyloid cervical arthropathy in long term hemodialysis
    Jessica Mandrioli
    J Neurol 253:1229-31. 2006
  40. ncbi Critical role for DP5/Harakiri, a Bcl-2 homology domain 3-only Bcl-2 family member, in axotomy-induced neuronal cell death
    Kazunori Imaizumi
    Division of Structural Cellular Biology, Nara Institute of Science and Technology, Nara 630 0101, Japan
    J Neurosci 24:3721-5. 2004
    ..These results indicate that DP5 plays an important role in neuronal cell death induced by axotomy and NGF deprivation through the regulation of mitochondrial function and caspase-3 activation...
  41. ncbi [Isolated hypoglossal nerve paralysis: a case report]
    Güçlü Kaan Beriat
    Ufuk Üniversitesi Tip Fakültesi Kulak Burun Boğaz Hastaliklari Anabilim Dali, Ankara, Turkey
    Kulak Burun Bogaz Ihtis Derg 20:205-9. 2010
    ..Recurrence of the tumor was thought to be the cause of the isolated hypoglossal nerve paralysis at first, however late toxicity of radiotherapy was found to be the etiological factor after detailed examinations...
  42. ncbi Unilateral hypoglossal neurapraxia following endotracheal intubation for total shoulder arthroplasty
    Bryan Haslam
    AANA J 81:233-6. 2013
    ..In suspected cases of hypoglossal neurapraxia, conservative therapeutic interventions may be warranted...
  43. ncbi [Isolated unilateral hypoglossal nerve paralysis: a report of two cases]
    Muzeyyen Dogan
    Marmara Universitesi Tip Fakültesi Kulak Burun Boğaz Hastaliklari Anabilim Dali, Istanbul
    Kulak Burun Bogaz Ihtis Derg 11:125-8. 2003
    ..No clinical improvement was observed during a six-month follow-up period...
  44. ncbi Tongue deviation in acute ischaemic stroke: a study of supranuclear twelfth cranial nerve palsy in 300 stroke patients
    T Umapathi
    Department of Neurology, National Neuroscience Institute, Singapore
    Cerebrovasc Dis 10:462-5. 2000
    ..The finding that it occurs relatively commonly in large (non-lacunar) infarcts and its association with dysphagia may have clinical utility...
  45. ncbi Unilateral compression neuropathy of the hypoglossal nerve due to head suspension orthosis in mitochondriopathy
    Josef Finsterer
    Department of Neurology, Krankenanstalt Rudolfstiftung, Vienna, Austria, Europe
    Int J Neurosci 114:1573-80. 2004
    ....
  46. ncbi [Deviated tongue]
    H S Fuessl
    MMW Fortschr Med 147:61-2. 2005
  47. ncbi Unilateral myokymia of the tongue after radiation therapy for cervical nodal melanoma
    Randal C Richardson
    Division of Pediatric Neurology, Department of Pediatrics, University of Washington Medical Center and Children s Hospital and Regional Medical Center, Seattle, WA, USA
    J Clin Neuromuscul Dis 10:122-5. 2009
    ..The earlier onset of myokymia than previous cases may represent more direct radiation exposure due to radiation site or the higher radiation dosage administered for treatment of melanomas...
  48. ncbi Hemifacial microsomia: a clinicoradiological report of three cases
    Manu Dhillon
    Department of Oral Medicine and Radiology, Kothiwal Dental College and Research Centre, Moradabad, India
    J Oral Sci 52:319-24. 2010
    ..All three cases had variable presentations ranging from the mildest form that included facial asymmetry and ear deformity to the most severe and unusual form with facial nerve paralysis and spine deformity...
  49. ncbi Hypoglossal schwannoma-successful reinnervation and functional recovery of the tongue following tumour removal and nerve grafting
    Tiit Mathiesen
    Department of Neurosurgery, Skull Base Center, Karolinska Hospital, Stockholm, Sweden
    Acta Neurochir (Wien) 151:837-41; discussion 841. 2009
    ..Hypoglossal nerve schwannomas are rare tumours that usually cause ipsilateral hypoglossal palsy. This report describes such lesions in two patients and suggests nerve grafting as part of the treatment regimen...
  50. ncbi Images in clinical medicine. Hypoglossal-nerve palsy
    Dimitrios I Zafeiriou
    Aristotle University of Thessaloniki, 54642 Thessaloniki, Greece
    N Engl J Med 350:e4. 2004
  51. ncbi Endoscopic management of a lower clival chondroid chordoma: case report
    Komatsu Mika
    Fukuoka University, Faculty of Medicine, Department of Neurosurgery, Fukuoka, Japan
    Turk Neurosurg 22:123-6. 2012
    ..Endonasal endoscopic surgery provided safe and reliable tumor resection for a lower clival lesion. We believe that this minimally invasive procedure should be considered as an alternative to traditional surgical treatment...
  52. ncbi [Conjugate deviation in ischemia of medial medullary oblongata--report of three cases]
    Yoshimasa Kinoshita
    Department of Neurosurgery, Munakata Suikokai General Hospital, Fukutsu shi, Fukuoka, Japan
    Brain Nerve 59:277-83. 2007
    ..The upper MMI will be characterized by a triad of contralateral hemiparesis, deep sensory disturbance and abnormal ocular motor findings...
  53. ncbi Unilateral cranial and phrenic nerve involvement in axonal Guillain-Barré syndrome
    Yumi Sakakibara
    Department of Neurology, Narita Red Cross Hospital, Narita, Japan
    Muscle Nerve 25:297-9. 2002
    ..The present report indicates that the cranial and phrenic nerves may be affected unilaterally in Guillain-Barré syndrome, and that there is clinical variability in the axonal subtype of this syndrome...
  54. ncbi Paraganglioma of the hypoglossal nerve
    Davide Santovito
    Unit of Vascular Surgery, Department of Medico Surgical Disciplines, University of Turin, Turin, Italy
    J Vasc Surg 49:1053-5. 2009
    ....
  55. doi Neurological picture. Multidetector-row computed tomography in the diagnosis of Collet-Sicard syndrome
    L T Lucato
    Department of Radiology, The Clinics Hospital of the University of Sao Paulo, School of Medicine, Sao Paulo, Brazil
    J Neurol Neurosurg Psychiatry 79:521. 2008
  56. ncbi Hypoglossal nerve palsy secondary to cervical spine involvement in rheumatoid arthritis: clinical and radiological features
    Abdel Rauf Zeina
    Department of Radiology, Hillel Yaffe Medical Center, 38100 Hadera, Israel
    Joint Bone Spine 76:547-9. 2009
    ..Pulse therapy with methylprednisolone followed by maintenance therapy with prednisone resulted in dramatic improvement. We also present the variety of diagnostic modalities helpful for the diagnosis and follow-up...
  57. ncbi [Bilateral hypoglossal nerve palsy following intubation]
    S Bramer
    Klinik fur Neurologie, Friedrich Schiller Universitat Jena
    Nervenarzt 77:204-7. 2006
    ..Hypoglossal nerve palsy following intubation might have a favourable prognosis as long as continuity of the nerve sheath is maintained...
  58. ncbi A cylindrical extracranial cranial base neurinoma of the hypoglossal nerve: a rare tumor with a rare localization: case report
    Hi Jae Heiroth
    Department of Neurosurgery, Heinrich Heine University, Dusseldorf, Germany
    Neurosurgery 65:E212-3; discussion E213. 2009
    ..The isolated extracranial localization of the neurinoma of the hypoglossal nerve adjacent to the cranial base as described in this case report is extremely rare...
  59. ncbi Transient contralateral hypoglossal nerve palsy following third molar surgery under day-case general anaesthesia: a case report and review of the literature
    J Dearing
    Department of Oral and Maxillofacial Surgery, Peterborough Hospitals NHS Trust, UK
    Br J Oral Maxillofac Surg 36:24-6. 1998
    ....
  60. ncbi Spontaneous bilateral internal carotid artery dissection with hypoglossal nerve palsy
    E Pakdemirli
    Pamukkale University, School of Medicine, Department of Radiology, Denizli, Turkey
    Comput Med Imaging Graph 25:373-8. 2001
    ..We report on a 52-year-old-male presented with bilateral extracranial internal artery dissection and twelfth nerve palsy and review the previous literature...
  61. ncbi Hypoglossal nerve palsy after posterior screw placement on the C-1 lateral mass. Case report
    Jae Taek Hong
    Department of Neurosurgery, St Vincent Hospital, The Catholic University of Korea, Suwon, Korea
    J Neurosurg Spine 5:83-5. 2006
    ..The hypoglossal nerve is one of the structures that can be damaged during C-1 lateral mass screw placement...
  62. pmc Large cystic hypoglossal schwannoma with fluid-fluid level: a case report
    Wen Chen Li
    Department of Neurosurgery, First Hospital of Jilin University, Changchun, China
    Skull Base 20:193-7. 2010
    ..In this report, we discuss the possible reasons for the absence of hypoglossal nerve palsy and the potential mechanism of the formation of the fluid-fluid level, and we consider the treatment of this lesion...
  63. ncbi Transient hemiglossal denervation during acute internal capsule infarct in the setting of dysarthria-clumsy hand syndrome
    David S Titelbaum
    Department of Radiology, Shields Health Care, Brockton, Massachusetts 02301, USA
    AJNR Am J Neuroradiol 31:1266-7. 2010
    ..Awareness of the findings in this case will facilitate appropriate diagnosis, provide neuroanatomic explanation, and prevent misdiagnosis...
  64. ncbi Dysarthria as the isolated clinical symptom of borreliosis--a case report
    K Gustaw
    Outpatients Neurological Department, Institute of Agricultural Medicine, Jaczewskiego 2, P O Box 185, 20 950 Lublin, Poland
    Ann Agric Environ Med 8:95-7. 2001
    ..Needle EMG examination confirmed the diagnosis of mono-neuropathy of left hypoglossal nerve. The study confirms the fact that neuroborreliosis may evoke chronic consequences...
  65. ncbi Intraoperative monitoring during surgery for hypoglossal schwannoma
    Mami Ishikawa
    Department of Neurosurgery, Saitama Medical Center, Jichi Medical University, 847 Amanumacho, Omiyaku, Saitama shi, 330 8503 Saitama ken, Japan
    J Clin Neurosci 17:1053-6. 2010
    ..This suggests that tongue EMG is a useful monitoring tool to enhance neurological outcome following removal of tumors in this region...
  66. ncbi Hypoglossal nerve palsy caused by a large vagal paraganglioma: case report
    Nikolaos Papadogeorgakis
    Department of Oral and Maxillofacial Surgery, Evangelismos General Hospital, Dental School, University of Athens, Greece
    Br J Oral Maxillofac Surg 47:69-70. 2009
    ..We present a vagal paraganglioma in a 74-year-old woman, who presented with dysphagia, dysarthria and hoarseness...
  67. ncbi Bilateral hypoglossal nerve injury following the use of the laryngeal mask airway
    A Stewart
    Department of Anaesthesia, St Helier Hospital, Wrythe Lane, Carshalton, Surrey SM5 1AA, UK
    Anaesthesia 57:264-5. 2002
    ..We discuss the possible aetiology of the injury and review the literature describing injuries to the hypoglossal nerve...
  68. ncbi Hypoglossal neurinoma presenting with intratumoral hemorrhage
    Toshiyuki Takahashi
    Department of Neurosurgery, Kohnan Hospital, Sendai, Japan
    J Clin Neurosci 9:716-9. 2002
    ..Extensive hemorrhage was present, as was necrosis. Thickening and hyalinization of arterial walls, a common occurrence in neurinomas, may have contributed to symptomatic intratumoral hemorrhage...
  69. ncbi Hypoglossal schwannoma in the submandibular space
    Ke Chang Chang
    Department of Otolaryngology, Mackay Memorial Hospital, Taipei, Taiwan
    J Laryngol Otol 116:63-4. 2002
    ..Solitary and extracranial schwannomas are extremely rare. We report a case of submandibular hypoglossal schwannoma along with its clinical course and management...
  70. ncbi Intracranial extradural schwannoma of the 12th cranial nerve. Case illustration
    Emiliano Passacantilli
    Department of Radiology, Section of Neuroradiology, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona, USA
    J Neurosurg 98:219. 2003
  71. ncbi Isolated unilateral hypoglossal nerve paralysis caused by an atlanto-occipital joint synovial cyst
    A Mujic
    Department of Neurosurgery, Royal Hobart Hospital, Hobart, Tasmania, Australia
    J Clin Neurosci 10:492-5. 2003
    ..The anatomy of the hypoglossal nerve, its blood supply and the relationship of the nerve to the atlanto-occipital joint are reviewed, along with the common causes of isolated hypoglossal nerve paralysis...
  72. ncbi Unilateral macroglossia as sole presenting manifestation of internal carotid artery dissection
    Joerg Patrick Stübgen
    Department of Neurology and Neuroscience, Weill Cornell Medical College New York Presbyterian Hospital, 525 E 68th St, New York, NY 10065 4897, USA
    Ear Nose Throat J 90:434-6. 2011
    ..The hypoglossal neuropathy resulted from compression by the pseudoaneurysmal ICA dilatation or ischemia from interruption of the vasa nervorum...
  73. ncbi Lemierre syndrome associated with 12th cranial nerve palsy--a case report and review
    Kerstin Blessing
    Centre for Pediatrics and Adolescent Medicine, University Hospital Freiburg, Germany
    Int J Pediatr Otorhinolaryngol 77:1585-8. 2013
    ..n.). We describe the unusual clinical features of a 12-year-old boy with Lemierre syndrome with isolated hypoglossal nerve palsy - the latter symptom is an extremely rare manifestation of this disease. ..
  74. ncbi A schwannoma of the hypoglossal nerve presenting as a malignant tumour of the oral floor
    N Fakhry
    CHU La Timone, Service d ORL et de Chirurgie Cervico faciale, 264, rue Saint Pierre, 13385 Marseille Cedex 05, France
    Rev Laryngol Otol Rhinol (Bord) 130:189-91. 2009
    ..We describe a case of an unusual schwannoma of the hypoglossal nerve presenting clinically as a malignant tumour of the floor of the oral cavity...
  75. ncbi A carotid artery dissection presenting with dysphagia due to a dilation of upper oesophagus
    M Vaes
    Department of Internal Medicine, CHU Vésale, Montigny le Tilleul, Belgium
    Acta Neurol Belg 107:91-3. 2007
    ..His main symptom was a dysphagia due to a dilation of his upper oesophagus; the pneumogastric nerve being responsible for the parasympathic innervation of the upper muscles of the oesophagus...
  76. ncbi Isolated hypoglossal nerve palsy: a harbinger of malignancy
    S G Khoo
    Department of Otolaryngology Head and Neck Surgery, Mid Western Regional Hospital, Limerick, Ireland
    J Laryngol Otol 121:803-5. 2007
    ..This case illustrates the fact that magnetic resonance imaging is the investigation of choice in assessing the entire course of the hypoglossal nerve...
  77. ncbi Radiation-induced hypoglossal nerve palsy
    S Billan
    Isr Med Assoc J 9:134. 2007
  78. ncbi Mild hypoxic preconditioning attenuates injury-induced NADPH-d/nNOS expression in brainstem motor neurons of adult rats
    I Hua Wei
    Department of Anatomy and Cell Biology, College of Medicine, China Medical University, Taichung, Taiwan
    J Chem Neuroanat 35:123-32. 2008
    ..The MHPC treatment might induce minute amounts of NO to alter the state of milieu of the experimental animals to protect against the PNCI...
  79. ncbi Intraneural ganglion cyst
    Robert J Spinner
    J Neurosurg 104:990-2; author reply 992. 2006
  80. ncbi Lingual atrophy and dolichoectatic artery
    G Castelnovo
    Department, Hopital Caremeau, CHU Nimes, 2 Av du prof Debrie, Nimes, France
    Neurology 61:1121. 2003
  81. ncbi A case of intracranial hypoglossal neurinoma without hypoglossal nerve palsy: operative view of the preserved rostral trunk
    Y Kikkawa
    Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
    Minim Invasive Neurosurg 50:296-9. 2007
    ..The tumor only developed intracranially, and since the rostral trunk of the hypoglossal nerve was intact, the patient did not present with hypoglossal nerve palsy preoperatively...
  82. ncbi Unilateral spontaneous dissection of the internal carotid artery presenting as hypoglossal nerve palsy
    Harriet C Hafkamp
    Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Maastricht, P Debeyelaan 25, P O Box 5800, 6202 AZ, Maastricht, The Netherlands
    Eur Arch Otorhinolaryngol 261:405-8. 2004
    ..The expansion of the circumference of the artery causes compression of the hypoglossal nerve resulting in a palsy. To the best of our knowledge this disorder has twice been dealt with in the otorhinolaryngological literature...
  83. ncbi Isolated hypoglossal nerve palsy due to a vascular anomaly
    R M Graham
    Department of Oral and Maxillofacial Surgery, The Royal Blackburn Hospital, Blackburn BB2 3HH, UK
    Int J Oral Maxillofac Surg 36:759-61. 2007
    ..This case demonstrates that excellent images can be obtained from MR imaging, and also emphasises that other pathologies must be considered in the differential diagnosis of hypoglossal nerve palsy...
  84. ncbi Symmetrical peripheral gangrene and neurological manifestations in Plasmodium falciparum malaria
    Ratan K Kotokey
    Department of Medicine, Assam Medical College and Hospital, Dibrugarh 786 002, Assam, India
    J Assoc Physicians India 59:449-51. 2011
    ..The special feature of this case is that the patient had bilateral hypoglossal nerve palsy and the signs of pyramidal tract involvement which improved after conservative management...
  85. ncbi Trans-cerebellomedullary fissure approach with special reference to lateral route
    Masatou Kawashima
    Department of Neurosurgery, Faculty of Medicine, Saga University, 5 1 1 Nabeshima, Saga 849 8501, Japan
    Neurosurg Rev 32:457-64. 2009
    ..A tumor is safely removed by this approach with easy feeder or tumor bed controls, especially if it is anchored at the lateral part of the CMF as is the jugular tubercle meningioma...
  86. pmc A case of idiopathic isolated hypoglossal nerve palsy in a Korean child
    Ji Hoi Yoon
    Department of Pediatrics, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon, Korea
    Korean J Pediatr 54:515-7. 2011
    ..Fifteen days after the onset of symptoms, the patient recovered completely. Herein, we report a case of idiopathic isolated HNP in a Korean male...
  87. ncbi Jefferson fracture resulting in Collet-Sicard syndrome
    B Connolly
    Department of General Surgery, Army Medical Center, Tacoma, Washington, USA
    Spine (Phila Pa 1976) 25:395-8. 2000
    ..A case report and review of the literature...
  88. ncbi Isolated 12th cranial nerve palsy as a complication of multiple myeloma
    Dawn Tucker
    Department of Haematology, Dunedin Public Hospital, Dunedin, New Zealand
    Br J Haematol 124:1. 2004
  89. ncbi A case of unilateral hypoglossus nerve palsy associated with chordoma in the region of clivus
    Fahd Ali Alharbi
    Department of Otorhinolaryngology, Head and Neck Surgery, Medical University of Hannover, Carl Neuberg Strasse, 30625 Hannover, Germany
    Eur Arch Otorhinolaryngol 266:2001-3. 2009
    ..A carbon ion radiotherapy is an effective treatment for chordomas of the skull base with minimal side effects. Close interdisciplinary collaboration between ORL, neuroradiology, pathology and oncology is desirable for effective therapy...
  90. ncbi Transcranial magnetic stimulation in brainstem lesions and lesions of the cranial nerves
    Peter P Urban
    Department of Neurology, University of Mainz, Langenbeckstr 1, D 55101 Mainz, Germany
    Suppl Clin Neurophysiol 56:341-57. 2003
  91. ncbi Tapia's syndrome after repair of a fractured mandible
    Soumya A Kashyap
    Department of Oral and Maxillofacial Surgery, Leeds Dental Institute, Leeds, West Yorkshire, United Kingdom
    Br J Oral Maxillofac Surg 48:53-4. 2010
    ..Post-operatively he developed hoarseness of voice and dyspnoea during speech, with deviation of the tongue on protrusion. After excluding intracranial and surgical causes, a clinical diagnosis of Tapia's syndrome was made...
  92. ncbi Clinical study of parapharyngeal space tumours
    H Chijiwa
    Department of Otolaryngology Head and Neck Surgery, Kurume University School of Medicine, Kurume, Japan
    J Laryngol Otol 123:100-3. 2009
    ..In consideration of the high incidence of post-operative complications, the surgical approach should therefore be carefully selected when treating patients with parapharyngeal space tumours...
  93. ncbi Current management of head and neck schwannomas
    Roger V Moukarbel
    Department of Otolaryngology Head and Neck Surgery, The American University of Beirut, Beirut, Lebanon
    Curr Opin Otolaryngol Head Neck Surg 13:117-22. 2005
    ..The purpose of this review is to discuss the contemporary management of head and neck schwannomas by reviewing the literature and presenting the authors' experience...
  94. ncbi Hypoglossal neuropathy in Lewis-Sumner syndrome masquerading as motor neuron disease
    M D Weiss
    Department of Neurology, University of Washington Medical Center, Seattle, WA 98195, USA
    Neurology 67:175-6. 2006
  95. ncbi Endoscope-assisted microsurgical resection of an intraneural ganglion cyst of the hypoglossal nerve
    Jörg Baldauf
    Departments of Neurosurgery and Neuropathology, Ernst Moritz Arndt University, Greifswald, Germany
    J Neurosurg 103:920-2. 2005
    ..The occurrence of an intraneural ganglion cyst at the hypoglossal nerve is very rare. This case exemplifies an atypical location of a synovial cyst with cranial nerve involvement...
  96. ncbi [Headache and hypoglossal nerve palsy]
    J Schmutzhard
    Universitätsklinik für Hals, Nasen und Ohrenheilkunde, Medizinische Universitat Innsbruck, Innsbruck, Austria
    HNO 57:690-2. 2009
    ..Isolated hypoglossal nerve palsy without participation of other cranial nerves is rare so that when headaches simultaneously occur, a dissection of the internal carotid artery is indicated, as in the case presented here...
  97. ncbi Isolated unilateral hypoglossal nerve palsy after minor head trauma
    Vivek Kaushik
    University Department of Otolaryngology Head and Neck Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M139WL, UK
    Clin Neurol Neurosurg 105:42-7. 2002
    ..We describe a case that resulted from minor trauma. An underlying skull base malformation may have been a predisposing factor...
  98. ncbi Idiopathic hypoglossal nerve laceration detected by high-resolution three-dimensional constructive interference in steady state magnetic resonance imaging
    Ken Sakushima
    Department of Neurology, Hokkaido University Graduate School of Medicine, and Department of Radiology, Hokkaido University Hospital, Sapporo, Japan
    J Neuroimaging 21:e177-9. 2011
    ..In such patients, the cause of the defect is not always apparent and 3-dimensional CISS MRI may resolve this issue...
  99. ncbi Surgical treatment of dumbbell-shaped hypoglossal schwannoma via a pure endoscopic transoral approach
    Qiuhang Zhang
    Skull Base Surgery Center, Department of Neurosurgery, Capital Medical University Xuanwu Hospital, No 45 Changchunjie Street, Xicheng District, Beijing, Peoples Republic of China
    Acta Neurochir (Wien) 154:267-75; discussion 275. 2012
    ..This report describes such lesions in three patients that were completely removed via a purely endoscopic transoral approach...
  100. ncbi Hemilingual spasm: defining a new entity, its electrophysiological correlates and surgical treatment through microvascular decompression
    Leisha L Osburn
    Clarian Neuroscience, Department of Neurophysiology, Indianapolis, Indiana 46202, USA
    Neurosurgery 67:192-5; discussion 196. 2010
    ....
  101. ncbi The midline suboccipital subtonsillar approach to the hypoglossal canal: surgical anatomy and clinical application
    M Tatagiba
    Department of Neurosurgery, University of Tubingen, Tubingen, Germany
    Acta Neurochir (Wien) 148:965-9. 2006
    ..There is no necessity of condylar resections. The surgical anatomy of the subtonsillar approach is described and illustrated by an example of a case...