Genomes and Genes
Summary: Conditions characterized by recurrent paroxysmal neuronal discharges which arise from a focal region of the brain. Partial seizures are divided into simple and complex, depending on whether consciousness is unaltered (simple partial seizure) or disturbed (complex partial seizure). Both types may feature a wide variety of motor, sensory, and autonomic symptoms. Partial seizures may be classified by associated clinical features or anatomic location of the seizure focus. A secondary generalized seizure refers to a partial seizure that spreads to involve the brain diffusely. (From Adams et al., Principles of Neurology, 6th ed, pp317)
Publications212 found, 100 shown here
- Common genetic variation and susceptibility to partial epilepsies: a genome-wide association studyDalia KasperaviciÅ«te
Department of Clinical and Experimental Epilepsy, UCL Institute of Neurology, Queen Square, London, WC1N 3BG, UK
Brain 133:2136-47. 2010b>Partial epilepsies have a substantial heritability. However, the actual genetic causes are largely unknown...
- Interictal diffusion MRI in partial epilepsies explored with intracerebral electrodesLionel Thivard
Epileptology Unit, INSERM U739, Faculté de Médecine Pitié Salpêtrière, Paris, France
Brain 129:375-85. 2006..These encouraging, preliminary results, suggest that DTI examinations may provide accurate spatial data on the location and extent of the epileptogenic network in extratemporal lobe epilepsies...
- Efficacy and tolerability of the new antiepileptic drugs II: treatment of refractory epilepsy: report of the Therapeutics and Technology Assessment Subcommittee and Quality Standards Subcommittee of the American Academy of Neurology and the American EpileJ A French
University of Pennsylvania, Philadelphia, USA
Neurology 62:1261-73. 2004....
- Dominant partial epilepsies. A clinical, electrophysiological and genetic study of 19 European familiesF Picard
INSERM U 398, Clinique Neurologique, Strasbourg, France
Brain 123:1247-62. 2000..The evolution of familial partial epilepsies, which exhibit great intrafamilial variability, is not always benign...
- Using voxel-specific hemodynamic response function in EEG-fMRI data analysisYingli Lu
Montreal Neurological Institute, McGill University, 3801 University Street, Montreal, Quebec, Canada H3A 2B4
Neuroimage 32:238-47. 2006..The results suggest that the fixed HRF methods may not be the most appropriate for the analysis of epileptic activity with EEG-fMRI, and the deconvolution method may be a better choice...
- Stiripentol in childhood partial epilepsy: randomized placebo-controlled trial with enrichment and withdrawal designCatherine Chiron
INSERM U663, Service de Neurologie et Metabolisme, Hopital Necker Enfants Malades, 149 rue de Sevres, F 75015 Paris, France
J Child Neurol 21:496-502. 2006....
- The role of PET in presurgical assessment of partial epilepsiesFrancois Mauguiere
Department of Functional Neurology and Epileptology, Neurological Hospital, Lyon, France
Epileptic Disord 6:193-215. 2004In the presurgical assessment of drug refractory partial epilepsies PET represents a privileged means for investigating glucose metabolism and neurotransmission in the functional-deficit zone, defined as the region of cortex that is ..
- Basic mechanisms of partial epilepsiesUwe Heinemann
Johannes Muller Institute of Physiology, University of Medicine Berlin, Germany
Curr Opin Neurol 17:155-9. 2004b>Partial epilepsies are characterized by cell loss with consequences for neuronal organization, excitability, mnestic and cognitive functions and present with pharmaco-resistance and difficulties in clinical management...
- Event-related fMRI with simultaneous and continuous EEG: description of the method and initial case reportL Lemieux
Epilepsy Research Group, Department of Clinical Neurology, University College London, Queen Square, London WC1N 3BG, UK
Neuroimage 14:780-7. 2001..The time course of activation was comparable with the physiological hemodynamic response function (HRF). The new methodology could lead to novel and important applications in many areas of neuroscience...
- Cardiovascular autonomic functions in well-controlled and intractable partial epilepsiesShalini Mukherjee
Dept of Neurology, UT Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX, United States shalini
Epilepsy Res 85:261-9. 2009..Well-controlled (WcE) and intractable epilepsy (IE) subjects may present different autonomic profiles, which can be helpful in explaining the predisposition of the latter to SUDEP...
- The BOLD response to interictal epileptiform dischargesChristian G Bénar
Montreal Neurological Institute, McGill University, Montreal, Quebec, H3A 2B4, Canada
Neuroimage 17:1182-92. 2002..The possibility of a longer HRF could be used to improve statistical detection of activation in simultaneous EEG-fMRI. The variability in average HRFs across patients could reflect in part different pathophysiological mechanisms...
- Guidelines for imaging infants and children with recent-onset epilepsyWilliam D Gaillard
Department of Neuroscience, Children s National Medical Center, George Washington University, Washington, DC 20010, USA
Epilepsia 50:2147-53. 2009..When available, MRI is preferred to CT because of its superior resolution, versatility, and lack of radiation...
- Preictal headache in partial epilepsyA E Yankovsky
Department of Neurology and Neurosurgery, Montreal Neurological Hospital and Institute, McGill University, Montreal, Quebec, Canada
Neurology 65:1979-81. 2005..Migrainous features were found in four. After surgery, all seven seizure-free patients and two with rare seizures were free of PIHA. It may be a useful lateralizing sign in patients with TLE...
- Partial epilepsies: overviewFernando Cendes
Departamento de Neurologia, FCM, UNICAMP, Campinas, SP, Brazil
Arq Neuropsiquiatr 61:1-7. 2003
- EEG-fMRI of epileptic spikes: concordance with EEG source localization and intracranial EEGChristian G Bénar
Montreal Neurological Institute, 3801 University Street, Montreal, Quebec, Canada H3A 2B4
Neuroimage 30:1161-70. 2006..This could reflect an increase of metabolism linked to the presence of slow waves, which suggests that fMRI is a new source of information on the mechanisms of spike generation...
- Seizure-related headache in patients with epilepsyFeray Karaali-Savrun
Istanbul University, Cerrahpasa School of Medicine, Department of Neurology, 34303 Cerrahpasa, Istanbul, Turkey
Seizure 11:67-9. 2002..The type of pain in PoiH was 'throbbing' in complex partial seizures and 'steady' in GTCS...
- Pregabalin add-on therapy using a flexible, optimized dose schedule in refractory partial epilepsies: a double-blind, randomized, placebo-controlled, multicenter trialByung In Lee
Department of Neurology, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea
Epilepsia 50:464-74. 2009..To evaluate the efficacy and safety of pregabalin (PGB) as adjunctive therapy, using a flexible-dosing schedule in Korean patients with refractory partial-onset seizures...
- Characteristics of headache associated with intractable partial epilepsyAlexei E Yankovsky
Department of Neurology and Neurosurgery, Montreal Neurological Hospital and Institute, McGill University, Montreal, Quebec, Canada
Epilepsia 46:1241-5. 2005..The association between headache (HA) and epilepsy is well known. However, few previous studies characterized HA types and head sensations (HSens) in large populations of individuals with well-defined forms of epilepsy...
- Is it possible to anticipate seizure onset by non-linear analysis of intracerebral EEG in human partial epilepsies?K Lehnertz
Clinic of Epileptology, University of Bonn, Germany
Rev Neurol (Paris) 155:454-6. 1999..In this review we present recent findings from nonlinear time series analysis of intracranially recorded EEG that may allow to forecast seizure onset in patients with partial epilepsy...
- Spatio-temporal imaging of focal interictal epileptiform activity using EEG-triggered functional MRIK Krakow
MRI Unit, National Society for Epilepsy, Chalfont St. Peter, Buckinghamshire SL9 0RJ, UK
Epileptic Disord 3:67-74. 2001..The superior spatial resolution obtainable through EEG-triggered fMRI may provide an additional non-invasive tool in the presurgical evaluation of patients with intractable focal seizures...
- Efficacy and safety of levetiracetam (up to 2000 mg/day) in Taiwanese patients with refractory partial seizures: a multicenter, randomized, double-blind, placebo-controlled studyJing Jane Tsai
Department of Neurology, National Cheng Kung University Hospital and Medical College of National Cheng Kung University, Tainan, Taiwan
Epilepsia 47:72-81. 2006..To assess the efficacy and safety of adjunctive levetiracetam (LEV) therapy in controlling partial-onset seizures refractory to other antiepileptic drugs (AEDs) in a multicenter study in Taiwanese adults...
- Efficacy and tolerability of levetiracetam 3000 mg/d in patients with refractory partial seizures: a multicenter, double-blind, responder-selected study evaluating monotherapy. European Levetiracetam Study GroupE Ben-Menachem
Department of Clinical Neuroscience, Sahlgrenska, University Hospital, Goteborg, Sweden
Epilepsia 41:1276-83. 2000..To evaluate the efficacy and tolerability of levetiracetam (LEV) monotherapy in selected patients with refractory partial seizures...
- Multicenter double-blind, randomized, placebo-controlled trial of levetiracetam as add-on therapy in patients with refractory partial seizures. European Levetiracetam Study GroupS D Shorvon
The National Hospital for Neurology and Neurosurgery, London, England
Epilepsia 41:1179-86. 2000..To evaluate the efficacy and tolerability of levetiracetam (LEV, Keppra) as add-on therapy in patients with refractory partial seizures...
- Chronic epileptogenesis requires development of a network of pathologically interconnected neuron clusters: a hypothesisA Bragin
Department of Neurology, UCLA School of Medicine, Los Angeles, California 90095 1769, USA
Epilepsia 41:S144-52. 2000....
- Structural abnormalities remote from the seizure focus: a study using T2 relaxometry at 3 TR S Briellmann
Brain Research Institute, Austin Health, Melbourne, Australia
Neurology 63:2303-8. 2004..To determine the extent and severity of mesial temporal and subcortical signal abnormalities in patients with partial epilepsy...
- Non-invasive epileptic focus localization using EEG-triggered functional MRI and electromagnetic tomographyM Seeck
Department of Neurology, University Hospital of Geneva, Switzerland
Electroencephalogr Clin Neurophysiol 106:508-12. 1998..This approach, i.e. the combination of EEG-triggered fMRI and 3D EEG source analysis, represents a promising additional tool for presurgical epilepsy evaluation allowing precise non-invasive identification of the epileptic foci...
- Is the left cerebral hemisphere more prone to epileptogenesis than the right?M D Holmes
EEG and Clinical Neurophysiology Laboratory, Harborview Medical Center, Box 359722, 325 Ninth Ave, Seattle, Washington, USA
Epileptic Disord 3:137-41. 2001..To determine if there is evidence that the left cerebral hemisphere is more prone to epileptogenesis than the right hemisphere...
- [The concept of an epileptogenic network in human partial epilepsies]F Bartolomei
INSERM, U751, 13000 Marseille, France
Neurochirurgie 54:174-84. 2008..The emergence of clinical signs in the seizure depend on these phenomena, which in some cases can mimic a normal cognitive process or, on the contrary, lead to a deep rupture in normal cerebral functioning...
- EEG-triggered functional MRI of interictal epileptiform activity in patients with partial seizuresK Krakow
The Epilepsy Research Group and NMR Research Unit, Department of Clinical Neurology, Institute of Neurology, London, United Kingdom
Brain 122:1679-88. 1999....
- Meta-analysis and indirect comparisons of levetiracetam with other second-generation antiepileptic drugs in partial epilepsyChristian Otoul
UCB Pharma, Braine l Alleud, Belgium
Clin Neuropharmacol 28:72-8. 2005..These meta-analyses give only short-term efficacy and safety data. Comparative clinical trials and long-term studies of these agents are needed to confirm these findings...
- Treatment of partial seizures with gabapentin: double-blind, placebo-controlled, parallel-group studyToshio Yamauchi
Saitama Medical School, Saitama, Japan
Psychiatry Clin Neurosci 60:507-15. 2006..Favorable tolerability of gabapentin was confirmed also in a Japanese population, consistent with previous global studies...
- Hemodynamic correlates of epileptiform discharges: an EEG-fMRI study of 63 patients with focal epilepsyAfraim Salek-Haddadi
Department of Clinical and Experimental Epilepsy, Institute of Neurology, Queen Square, London, UK
Brain Res 1088:148-66. 2006..These findings provide important new information on the optimal use and interpretation of EEG-fMRI in focal epilepsy and suggest a possible role for EEG-fMRI in providing new targets for invasive EEG monitoring...
- Do children with benign rolandic epilepsy have a higher prevalence of migraine than those with other partial epilepsies or nonepilepsy controls?Elaine C Wirrell
Department of Pediatrics and Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
Epilepsia 47:1674-81. 2006..By using revised International Headache Society (IHS-R) criteria, we compared the prevalence of migraine in children with BREC with that of those (a) with cryptogenic/symptomatic partial epilepsy and (b) without epilepsy...
- Progress in the genetics of the partial epilepsiesR Ottman
Gertrude H Sergievsky Center and Mailman School of Public Health Department of Epidemiology Columbia University, New York, New York 10032 3702, USA
Epilepsia 42:24-30. 2001The importance of genetic contributions to the partial epilepsies is now well established...
- Levetiracetam, oxcarbazepine, remacemide and zonisamide for drug resistant localization-related epilepsy: a systematic reviewA G Marson
Department of Neurological Science, Clinical Sciences Centre for Research and Education, University of Liverpool, Lower Lane, Fazakerley, Liverpool L9 7LJ, UK
Epilepsy Res 46:259-70. 2001..To undertake a systematic review and meta-analysis of placebo controlled add-on trials of levetiracetam, oxcarbazepine, remacemide and zonisamide for patients with drug resistant localization related epilepsy...
- Mapping of spikes, slow waves, and motor tasks in a patient with malformation of cortical development using simultaneous EEG and fMRIBeate Diehl
MRI Unit, Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College, London, UK
Magn Reson Imaging 21:1167-73. 2003..In conclusion, continuous EEG-fMRI is useful to compare the functional mapping of epileptiform activity and eloquent cortices in individual patients...
- Characteristics of postictal headache in patients with partial epilepsyM Ito
Tenshi Hospital, Kita 12, Higashi 3 Higashi ku, Sapporo 065 8611, Japan
Cephalalgia 24:23-8. 2004..These results suggest that migraine-like PIH is related to particular regions of epileptogenic focus and that susceptibility to migraine headache predisposes to migraine-like PIH...
- Double-blind placebo-controlled trial of adjunctive levetiracetam in pediatric partial seizuresT A Glauser
Children s Hospital, Department of Neurology, Cincinnati, OH 45229, USA
Neurology 66:1654-60. 2006..To evaluate the efficacy and tolerability of levetiracetam (LEV) as adjunctive therapy in children (4 to 16 years) with treatment-resistant partial-onset seizures...
- The consequences of idiopathic partial epilepsies in relation to neuropsychological functioning: a closer look at the associated mathematical disabilityZ Hande Sart
Department of Educational Sciences, Faculty of Education, Bogazici University, Bebek, Istanbul, Turkey
Epileptic Disord 8:24-31. 2006Although the seizure prognosis is mostly favorable in idiopathic partial epilepsies, there is some empirical evidence showing that subtle neuropsychological impairments, with a consequent risk of academic underachievement, are not rare...
- Psychosocial impairments in children with epilepsy depend on the side of the focusKrystyna A Mathiak
Faculty of Psychology, University of Warsaw, Warsaw, Poland
Epilepsy Behav 16:603-8. 2009..The cognitive disturbances beginning in childhood may lead to the stronger emotional impairments observed in adults with left hemispheric seizures...
- Migraine and the benign partial epilepsies of childhood: evidence for an associationF Andermann
Montreal Neurological Hospital and Institute, Canada
Epileptic Disord 2:S37-9. 2000..Hopefully, this will stimulate further research into this intriguing association of two conditions which though they have different pathophysiology frequently coexist...
- Oxcarbazepine adjunctive therapy in infants and young children with partial seizuresJ E Piña-Garza
Vanderbilt Children s Hospital, Pediatric Neurology, Nashville, TN 37232, USA
Neurology 65:1370-5. 2005..To evaluate the efficacy, safety, and pharmacokinetics of oxcarbazepine as adjunctive therapy in infants and young children (1 month to < 4 years)...
- Diffusion tensor imaging of cryptogenic and acquired partial epilepsiesF J Rugg-Gunn
The MRI Unit, National Society for Epilepsy and Epilepsy Research Group, National Hospital for Neurology and Neurosurgery, Chalfont St. Peter, Gerrards Cross, Bucks SL9 0RJ, UK
Brain 124:627-36. 2001..These techniques are promising, non-invasive imaging methods for identifying the cause of partial seizures, and can contribute to pre-surgical evaluation...
- Lateralizing value of peri-ictal headache: A study of 100 patients with partial epilepsyA Bernasconi
Departments of Neurology and Neurosurgery, McGill University, and Montreal Neurological Institute and Hospital, Quebec, Canada
Neurology 56:130-2. 2001..001). For both groups, peri-ictal headache usually conformed to the diagnostic criteria for common migraine (18 of 30 = 60% in TLE; 7 of 17 = 41% in ETE)...
- Familial partial epilepsy with variable foci: clinical features and linkage to chromosome 22q12Samuel F Berkovic
Epilepsy Research Centre, University of Melbourne, Austin and Repatriation Medical Centre, Victoria, Australia
Epilepsia 45:1054-60. 2004..A gene for FPEVF was mapped to chromosome 22q12 in two distantly related French-Canadian families...
- Epileptic fast intracerebral EEG activity: evidence for spatial decorrelation at seizure onsetF Wendling
Laboratoire Traitement du Signal et de l Image, INSERM, Universite de Rennes 1, Campus de Beaulieu, Rennes, France
Brain 126:1449-59. 2003..high correlations between signals recorded during seizures), both giving insights into our understanding of pathophysiological processes involved in human partial epilepsies as well as in the interpretation of clinical semiology.
- A clinical and EEG study on idiopathic partial epilepsies with evolution into ESES spectrum disordersSema Saltik
SSK Goztepe Educational Hospital, Department of Pediatrics, Istanbul, Turkey
Epilepsia 46:524-33. 2005....
- [Treatment termination in children with idiopathic generalized epilepsy and cryptogenic focal epilepsy]Barbara Szwed-Białozyt
Katedra Pediatrii Klinika Neurologii Wieku Rozwojowego SAM Górnoślaskie Centrum Zdrowia Dziecka i Matki 40 752 Katowice, ul Medykow 16
Przegl Lek 60:5-9. 2003..The recurrence of the disease in children of the first group was only preceded in one third by irregularities in EEG; on the contrary, it occurred in two thirds of the second group. The morphology of changes was non-homogeneous...
- Prevalence of epilepsy in a rural district of central Lao PDRDuc Si Tran
Institut de la Francophonie pour la Médecine Tropicale, Vientiane, Lao PDR
Neuroepidemiology 26:199-206. 2006..To assess the prevalence of epilepsy in a rural district of Lao PDR and to describe the clinical and epidemiological profile of the disease...
- Periventricular nodular heterotopia: classification, epileptic history, and genesis of epileptic dischargesGiorgio Battaglia
Division of Experimental Neurophysiology and Epileptology, Neurological Institute C Besta, Milan, Italy
Epilepsia 47:86-97. 2006....
- Epileptic seizures in multiple sclerosis: clinical and EEG correlationsP Striano
Department of Neurological Sciences, Federico II University of Naples, Via Pansini 5, I 80131 Naples, Italy
Neurol Sci 24:322-8. 2003..Prognosis of epilepsy during the course of MS is usually good but the choice of AEDs remains a matter of debate...
- Absence seizures in patients with localization-related epilepsyAyako Sofue
Department of Pediatrics, Nagoya University Graduate School of Medicine, 65 Tsurumai Cho, Showa Ku, Nagoya, Aichi 466 8550, Japan
Brain Dev 25:422-6. 2003..AS in patients with LRE will be relatively benign and transient, and will respond well to antiepileptic drugs...
- A comparative study of vigabatrin vs. carbamazepine in monotherapy of newly diagnosed partial seizures in childrenWojciech Sobaniec
Department of Pediatric Neurology and Rehabilitation, Medical University of Białystok, Waszyngtona 17, PL 15 274 Białystok, Poland
Pharmacol Rep 57:646-53. 2005..No effect on the EEG background activity was observed in CBZ-treated children. VGB seems to be a safe and effective antiepileptic drug as primary monotherapy for epilepsy in children with similar proportion of side effects as CBZ...
- Do partial seizures predict an increased risk of seizure recurrence after antiepilepsy drugs are withdrawn?Karameh Y Hawash
Departments of Pediatrics and Neurology, Division of Pediatric Neurology, The Floating Hospital for Children, Tufts New England Medical Center, Tufts University School of Medicine, Boston, MA 02111, USA
J Child Neurol 18:331-7. 2003..A large, multicenter, prospective study looking at these and other potential risk factors for seizure recurrence is needed...
- Cerebellar volume and long-term use of phenytoinFelipe Antonio De Marcos
Department of Neurology, Faculdade de Ciências Médicas UNICAMP, Campinas, SP, Brazil
Seizure 12:312-5. 2003..To perform MRI cerebellum volumetry in patients exposed to phenytoin and to identify factors associated with cerebellar atrophy (CA)...
- Oxcarbazepine monotherapy in children and adolescents: a single-center clinical experienceSanjeev V Kothare
Division of Pediatric Neurology, Department of Pediatrics, St Christopher s Hospital For Children, Drexel University College of Medicine, Philadelphia, Pennsylvania 19134 1095, USA
Pediatr Neurol 35:235-9. 2006..5% became seizure-free. These findings suggest that oxcarbazepine monotherapy is effective and well tolerated in children and adolescents with partial epilepsy...
- [Surgery for intractable focal epilepsy in children]O Delalande
Fondation Adolphe de Rothschild, 25 rue Manin, 75019 Paris, France
Rev Neurol (Paris) 160:5S195-202. 2004..Our preliminary results concerning quality of life and socialization are encouraging and favor surgical treatment at an early stage...
- A patient with newly diagnosed partial and generalized seizuresJohn R Gates
Minnesota Epilepsy Group, 310 North Smith Avenue, Saint Paul, MN 55102, USA
Epilepsy Behav 4:S33-4. 2003
- Hypothalamic hamartoma and epilepsy in children: illustrative cases of possible evolutionsAlexis A Arzimanoglou
Epilepsy Unit, Child Neurology and Metabolic Diseases Department, University Hospital Robert Debré, Paris, France
Epileptic Disord 5:187-99. 2003....
- From hypothalamic hamartoma to cortex: what can be learnt from depth recordings and stimulation?Philippe Kahane
Neurophysiopathologie de l Epilepsie, CHU de Grenoble, France
Epileptic Disord 5:205-17. 2003..Whether this proposal of secondary epileptogenesis is valid or not remains a major issue, since it could provide arguments on the moment to discuss surgery...
- The treatment of patients with hypothalamic hamartomas, epilepsy and behavioural abnormalities: facts and hypothesesAndre Palmini
Porto Alegre Epilepsy Surgery Program, Hospital Sao Lucas da PUCRS, Porto Alegre, Brazil
Epileptic Disord 5:249-55. 2003..We conclude with a reflection on what we still do not understand as regards in the genesis and surgical management of the neuropsychiatric disabilities related to this disorder...
- Behavioural and neuropsychological problems in refractory paediatric epilepsiesMarc J C Boel
Rehabilitation and Epilepsy Unit, Reebergenlaan 4, B 2242 Pulderbos, Belgium
Eur J Paediatr Neurol 8:291-7. 2004..The only behavioural problem that was more frequent in females was self-induction of seizures...
- [Efficacy and safety of antiepileptic therapy in children (a comparative analysis of valproates and barbiturates)]O A Pylaeva
Zh Nevrol Psikhiatr Im S S Korsakova 104:61-5. 2004....
- [Eligibility for epilepsy surgery in children: review of the literature]A Kaminska
Service de Neurologie Pédiatrique et Service d Explorations Fonctionnelles, Groupe Hospitalier Cochin Saint Vincent De Paul, 74 à 82 avenue Denfert Rochereau, 75014 Paris, France
Rev Neurol (Paris) 160:5S220-31. 2004..The authors of these studies examined retrospectively the predictive factors of favorable outcome and defined the best selection criteria for surgery...
- Open prospective study on oxcarbazepine in epilepsy in children: a preliminary reportE Franzoni
Child Neuropsychiatry Unit, Bologna University, Italy
Seizure 15:292-8. 2006..To evaluate the long-term efficacy, tolerability, and safety of oxcarbazepine (OXC) in children with epilepsy...
- Efficacy of levetiracetam in pharmacoresistant continuous spikes and waves during slow sleepG Capovilla
Department of Child Neuropsychiatry, C Poma Hospital, Mantova, Italy
Acta Neurol Scand 110:144-7. 2004..Despite first description dates back to 1971, no agreement exists about CSWS treatment. The condition is rare and controlled clinical trials are very difficult to perform, so the reports about efficacy of different drugs are anecdotal...
- Mah-Jong-induced epilepsy: a special reflex epilepsy in Chinese societyChin Lung Wan
Department of Health and Leisure Management, Fooyin University, Kaohsiung, Taiwan
Seizure 14:19-22. 2005..This unusual reflex epilepsy is relatively benign in nature and antiepileptic drug therapy has uncertain benefits. It may be necessary to avoid playing the Mah-Jong game in order to prevent seizures...
- PET evidence for a role of the basal ganglia in patients with ring chromosome 20 epilepsyA Biraben
Service de Neurologie, CHU Pontchaillou, Rennes, France
Neurology 63:73-7. 2004..The hypothesis that these long-lasting seizures are associated with a reduction of striatal dopamine was addressed in the present study in drug-resistant patients with r(20) epilepsy using PET...
- [The use of lamotrigine in female patients]B Schmitz
Neurologische Klinik und Poliklinik, Charite, Campus Virchow Klinikum, Humboldt Universitat Berlin, Augustenburger Platz 1, 13353, Berlin, Germany
Nervenarzt 78:912-22. 2007..Due to its broad spectrum of action and to the lack of evidence for teratogenicity in monotherapy, lamotrigine (LTG) is an AED of first choice for women with epilepsy with child-bearing potential...
- Clinical experience with levetiracetam in childhood epilepsy: an add-on and mono-therapy trialL Lagae
University Hospitals KULeuven, Department of Paediatric Neurology, Herestraat 49, B3000 Leuven, Belgium
Seizure 14:66-71. 2005..Overall, these two clinical trials confirm that levetiracetam is a broad spectrum anti-epileptic drug with a favourable safety profile. The positive effect on behaviour needs further quantitative study...
- Detection of epileptiform activity by human interpreters: blinded comparison between electroencephalography and magnetoencephalographyMasaki Iwasaki
Department of Neurology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Epilepsia 46:59-68. 2005..Objectively to evaluate whether independent spike detection by human interpreters is clinically valid in magnetoencephalography (MEG) and to characterize detection differences between MEG and scalp electroencephalography (EEG)...
- Abnormalities in cardiac and respiratory function observed during seizures in childhoodMary E O'Regan
Fraser of Allander Neurosciences Unit, Royal Hospital for Sick Children, Yorkhill, Glasgow G3 8SJ, UK
Dev Med Child Neurol 47:4-9. 2005..We conclude that seizure activity can disrupt normal physiological regulation and control of respiratory and cardiac activity...
- Genital and sexual manifestations in drug-resistant partial epilepsyAddolorata Mascia
Epilepsy Surgery Unit, Department of Neurosciences, IRCCS Neuromed, Pozzilli, IS, Italy
Seizure 14:133-8. 2005..In particular, the most frequent genital automatisms consist in subtle phenomena while hypermotoric behaviour, such as pelvic rhythmic movements are quite rare. No lateralizing value for genital automatisms was disclosed...
- [Newly treated epilepsy: a French observational study]S Dupont
Unité d épileptologie, Clinique Neurologique Paul Castaigne, Hopital de la Pitie Salpetriere, Paris, France
Rev Neurol (Paris) 162:200-7. 2006..Data were available from a structured questionnaire delivered to all participating neurologists...
- Hypothalamic hamartoma with refractory epilepsy: surgical procedures and results in 18 patientsMartine Fohlen
unité de neurochirurgie pédiatrique, Fondation Ophtalmologique A de Rothschild, Paris, France
Epileptic Disord 5:267-73. 2003..To study the surgical procedures and results on seizures, in 18 patients with refractory epilepsy due to hypothalamic hamartoma...
- Early-onset occipital idiopathic epilepsy: a syndrome to be treated?Giovanni Lanzi
Child Neuropsychiatry Department, Neurological Institute Casimiro Mondino Foundation IRCCS, University of Pavia, Italy
J Child Neurol 18:72-4. 2003..We propose that the introduction of anti-epilepsy drugs be delayed for 6 months following epilepsy onset and be subsequently limited to patients with frequent seizure recurrence...
- Favorable outcome of epileptic blindness in childrenEli Shahar
Child Neurology Unit and Epilepsy Service, Meyer Children s Hospital, Rambam Medical Center, Rappaport School of Medicine, Haifa 31096, Israel
J Child Neurol 18:12-6. 2003..We therefore recommend performing a prompt EEG in any child presenting with acute visual obscuration, even in the absence of other epileptic phenomena...
- [Benign partial convulsions in adolescence]R Caraballo
, , Buenos Aires, Argentina
Rev Neurol 28:669-71. 1999..Neurological examination, EEG between crises and neuro-radiological studies were normal...
- Panayiotopoulos syndrome: diagnosis and managementP Parisi
Child Neurology and Paediatric Sleep Centre, La Sapienza University c o Sant Andrea Hospital, Rome, Italy
Neurol Sci 28:72-9. 2007..This review focuses on the main clinical and EEG features of this epilepsy underlining its typical and atypical symptoms and its management...
- Seizure semiology and neuroimaging findings in patients with midline spikesE Kutluay
Department of Neurology, University of Michigan, Ann Arbor, Michigan 48109, USA
Epilepsia 42:1563-8. 2001..Automotor seizures and tonic seizures are the most common semiologies. Focal radiologic abnormalities tend to be lateralized to one of the frontal lobes...
- Surgical outcome in tuberous sclerosis complex: a multicenter surveyDeepak Madhavan
Comprehensive Epilepsy Center, Department of Neurology, NYU Medical Center, 403 East 34th Street, New York, NY 10016, U S A
Epilepsia 48:1625-8. 2007..01). Ictal multifocality, mental retardation, and discordant EEG and MRI data showed a negative trend toward outcome, but were not significant...
- Spike-and-wave complexes and seizure exacerbation caused by carbamazepineS Kochen
Epilepsy Center, Neurology Division, Ramos Mejia Hospital, Buenos Aires University, CONICET, Buenos Aires, Argentina
Eur J Neurol 9:41-7. 2002..If EEG recordings become substantially worse, with more frequent and longer generalized SW bursts after initiation of CBZ therapy, patients should be carefully monitored in order to detect any sign of clinical impairment...
- Partial and generalized epilepsy with febrile seizures plus and a novel SCN1A mutationB Abou-Khalil
Department of Neurology, Vanderbilt University School of Medicine, Nashville, TN 37212, USA
Neurology 57:2265-72. 2001..GEFS+ has previously been linked to mutations in two genes encoding the voltage-gated sodium channel alpha-subunit (SCN1A) and beta1-subunit (SCN1B). We studied a large family with FS and partial as well as generalized seizure types...
- Seizure frequency and characteristics in children with Down syndromeH Goldberg-Stern
Epilepsy Center, Schneider Children's Medical Center of Israel, Petah Tiqva, Israel
Brain Dev 23:375-8. 2001..This regional study reinforces the relative association of seizures and Down syndrome. A prospective study including a national/international registry with emphasis on developmental assessment and long-term follow up is warranted...
- Epileptic event forewarning from scalp EEGV A Protopopescu
Oak Ridge National Laboratory, Oak Ridge, Tennessee 37831-6355, USA
J Clin Neurophysiol 18:223-45. 2001..They also assess the potential usefulness of the new measures for robust, accurate, and timely forewarning of epileptic events...
- Pediatric-onset gelastic seizures: clinical data and outcomeEli Shahar
Child Neurology Unit and Epilepsy Service, Meyer Children Hospital, Rambam Medical Center, Rappaport School of Medicine, Haifa, Israel
Pediatr Neurol 37:29-34. 2007..Thus, children with gelastic seizures may respond relatively well to drug therapy. Four of the 10 patients became seizure free with drug therapy; in three intractable symptomatic cases, surgery was tried but failed in two of the three...
- Utility of magnetoencephalography in the evaluation of recurrent seizures after epilepsy surgeryIsmail S Mohamed
Division of Neurology, Department of Pediatrics, The Hospital for Sick Children, Unviersity of Toronto, Toronto, Ontario, Canada
Epilepsia 48:2150-9. 2007..To study the role of magnetoencephalography (MEG) in the surgical evaluation of children with recurrent seizures after epilepsy surgery...
- Epileptic spasms in older pediatric patients: MEG and ictal high-frequency oscillations suggest focal-onset seizures in a subset of epileptic spasmsRajesh RamachandranNair
Division of Neurology, Department of Paediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada M5G1X8
Epilepsy Res 78:216-24. 2008....
- POLG1 mutations cause a syndromic epilepsy with occipital lobe predilectionBernt A Engelsen
Institute of Clinical Medicine, University of Bergen, Haukeland University Hospital, Bergen, Norway
Brain 131:818-28. 2008..All patients developed status epilepticus and 11 patient deaths were, all related to prolonged convulsive status epilepticus, including two with liver failure apparently precipitated by treatment with sodium valproate...
- [Epileptic seizures in childhood: from seizure type to diagnosis]M Milh
Service de Neurologie Pediatrique, Hôpital de la Timone Enfants, 265 rue Saint Pierre, 13005 Marseille, France
Arch Pediatr 15:216-22. 2008..Epileptic seizures cause distress to parents and the fear they experience of death must always be taken into account...
- Epilepsy surgery in patients with normal or nonfocal MRI scans: integrative strategies offer long-term seizure reliefPrasanna Jayakar
Department of Neurology, Miami Children s Hospital, Miami, FL, USA
Epilepsia 49:758-64. 2008..We report the outcome of a cohort predominantly of children with nonlesional intractable partial epilepsy undergoing resective surgery...
- [Panayiotopoulos syndrome--underdiagnosed and underrecognized epileptic syndrome]Y Otsuka
No To Hattatsu 40:231-4. 2008
- Alpha-methyl-l-tryptophan positron emission tomography in epilepsy with cortical developmental malformationsHiroyuki Wakamoto
Carman and Ann Adams Department of Pediatrics, Wayne State University School of Medicine, Detroit, Michigan, USA
Pediatr Neurol 39:181-8. 2008..When an alpha-[(11)C]methyl-l-tryptophan focus is detected, it likely represents the epileptogenic region to be resected...
- The clinical characterizations of benign partial epilepsy in infancyA Okumura
Department of Pediatrics, Juntendo University School of Medicine, Tokyo, Japan
Neuropediatrics 37:359-63. 2006..The main features of benign partial epilepsy in infancy were a high incidence of a cluster of seizures, short persistence of seizures, and normal initial interictal EEGs...
- Dynamic changes of ictal high-frequency oscillations in neocortical epilepsy: using multiple band frequency analysisAyako Ochi
The Divisions of Neurology, The Hospital for Sick Children and University of Toronto, Toronto, Ontario, Canada
Epilepsia 48:286-96. 2007..To characterize the spatial and temporal course of ictal high-frequency oscillations (HFOs) recorded by subdural EEG in children with intractable neocortical epilepsy...
- Lateralizing value of the auditory aura in partial seizuresIrene Florindo
Department of Neurological Sciences, University of Bologna, Bologna, Italy
Epilepsia 47:68-72. 2006..To describe the semiological features of auditory aura and to assess their possible lateralizing value in partial epilepsy...
- Surgical treatment of epilepsy in Sturge-Weber syndrome in childrenMarie Bourgeois
Service de Neurologie Pediatrique, Hopital Necker Enfants Malades, Paris, France
J Neurosurg 106:20-8. 2007....
- Is a cortical spike discharge "transferred" to the contralateral cortex via the corpus callosum?: An intraoperative observation of electrocorticogram and callosal compound action potentialsTomonori Ono
Department of Neurosurgery, Nagasaki University School of Medicine, Nagasaki, Japan
Epilepsia 43:1536-42. 2002....
- Epilepsy in fragile X syndromeElizabeth Berry-Kravis
Department of Pediatrics, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
Dev Med Child Neurol 44:724-8. 2002..Deficiency of FMRP (fragile X mental retardation protein) appears to lead to increased neuronal excitability and susceptibility to epilepsy, but particularly seems to facilitate mechanisms leading to the BFEC pattern...
- [Gelastic seizures: etiology, semiology, therapeutic perspectives]E L Usacheva
Zh Nevrol Psikhiatr Im S S Korsakova 103:10-6. 2003..Based on examination of 2 patients with gelastic seizures and hypothalamic hamartoma, clinical features, EEG characteristics and therapeutic perspectives for the disorder are discussed...
- Myoclonic-astatic epilepsy in a child with Sturge-Weber syndromeJoshua B Ewen
Department of Neurology, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Pediatr Neurol 36:115-7. 2007..In such cases, treatment with a broad-spectrum antiepileptic may be advantageous...
- ONTOGENY OF GABAA RECEPTOR COMPLEX MEASURED WITH PETOtto Muzik; Fiscal Year: 2002..abstract_text> ..
- Development of a galanin-based therapy for the treatment of refractory epilepsyH Steve White; Fiscal Year: 2013..The goal of this proposal is to apply our proprietary technology to develop a novel galanin-based therapy for treating this debilitating disorder. ..
- Neurophysiologically Based Responsive Pharmacotherapy for EpilepsyGregory A Worrell; Fiscal Year: 2013..Thus the Resume and Summary of Discussion is the final word on what the reviewers actually considered critical at the meeting. ..
- Psychosocial Impact of Genetics in EpilepsyRuth Ottman; Fiscal Year: 2013....
- Development of Hardware and Software for Clinical MEGNorman Tepley; Fiscal Year: 2010..The objective of this study is to establish MEG as a reliable clinical diagnostic tool. ..
- Detection and Control of EpilepsyDominique M Durand; Fiscal Year: 2013....
- Quantification of Thalamic Atrophy and Connectivity in Medial Temporal Lobe EpileDaniel S Barron; Fiscal Year: 2013..This research training will allow the applicant to learn neuroimaging analysis methods he will use as a neuroimaging researcher and epileptologist. ..
- CLINICAL RESEARCH PROGRAM FOR THE PARTIAL EPILEPSIESJEROME NONE ENGEL; Fiscal Year: 2010....
- Cognitive Impairment Moderated by Working Memory in Pediatric Partial EpilepsyMADISON MEHALANI BERL; Fiscal Year: 2013..This study characterizes the neural network of one aspect of executive functioning, namely working memory, in children with epilepsy using neuroimaging and neuropsychological measures. ..
- Exploratory genomic investigations of mesial temporal lobe epilepsyERIN L HEINZEN COX; Fiscal Year: 2013..Secondarily, this work may also provide an important foundation to motivate the study of the cell- specific genome in other diseases where tissue specimens are available. ..
- A Computational Approach for 3D Brain Source ImagingBin He; Fiscal Year: 2010..The availability of a noninvasive imaging technology to identify and image the epileptogenic foci would benefit numerous patients suffering from epilepsy and the healthcare system. ..
- Complementary treatment approach to epilepsySiegward Elsas; Fiscal Year: 2009..At the end of the award period, Dr. Elsas will have completed a clinical trial of a botanical and will be well positioned to obtain independent research funding. ..
- A Mouse Model of Inherited Frontal Lobe EpilepsyJim Boulter; Fiscal Year: 2006..The objective of these experiments is to examine possible synaptic mechanisms underlying epileptogenesis and to determine the effects of ADNFLE mutations on a4a2receptor-mediated function in vivo. ..
- EPILEPSY AS A NEUROLOGICAL MODEL OF SCHIZOPHRENIALaura Marsh; Fiscal Year: 2000..Hypothesis 3: Positive symptoms in ISZ and ESZ are related to neocortical temporal lobe MRI abnormalities; negative symptoms in ISZ and ESZ are correlated with frontal lobe abnormalities. ..
- MOLECULAR MECHANISMS OF HIPPOCAMPAL EPILEPTOGENESISCheolsu Shin; Fiscal Year: 2001DESCRIPTION (Adapted from Applicant's Abstract: Most partial epilepsies are acquired through brain injury and subsequent development of hyperexcitability by a process of epileptogenesis...
- ELECTRONIC DATA WAREHOUSE FOR EPILEPSY RESEARCHStephen Wong; Fiscal Year: 2002..Furthermore, its security architecture will ensure neurologic databases developed by the community to be sharable confidently and efficiently through the Web. ..
- EVOLUTION OF ALTERED INHIBITION IN EPILEPSYPATRICK MANGAN; Fiscal Year: 2002..The information gained in these studies will better define development of GABAergic deficiencies preceding seizures and will aid in the development of new anti-epileptogenic therapies. ..
- VALPROATE, PHENYTOIN AND INFANT OUTCOMENONA PHILLIPS; Fiscal Year: 1992..The proposed project, based on previous PHT research (58, 59, 60) and ongoing studies of VPA will provide a complete analysis of the potential effects of these two important drugs on the developing fetus and subsequent infant...
- COMPARISON OF SURGERY VS DRUG FOR EPILEPSYRICHARD DASHEIFF; Fiscal Year: 1993..Thus, this study will calculate the costs of both treatments, as well as the costs and resources used by the patients outside the treatment arms for the full 18 months. A cost/benefit analysis will then be performed...
- Mechanisms of seizure propagation in limbic cortexLEWIS HABERLY; Fiscal Year: 2007..These experiments will provide essential information about the spread of epileptic activity into normal cortex, and clues concerning how this spread can be curtailed. ..
- SUBCORTICAL METABOLIC ALTERATIONS IN EPILEPSYMichael Sperling; Fiscal Year: 1992..Overall objectives are to better define pathophysiological mechanisms of human epilepsy so that more effective therapeutic measures can be taken...
- LOCALIZATION OF EPILEPTIC FOCI WITH PET IN CHILDRENHarry Chugani; Fiscal Year: 2009..abstract_text> ..
- PILOT TRIAL OF THALAMIC STIMULATION FOR EPILEPSYRobert Fisher; Fiscal Year: 2001..A consortium of centers experienced in epilepsy research will collaborate on this project, which will move brain stimulation for epilepsy into the realm of a testable new therapy for intractable seizures. ..
- A Multidisciplinary Approach to Epilepsy GeneticsMelodie Winawer; Fiscal Year: 2009..abstract_text> ..
- FACILITATION OF EPILEPTIC ACTIVITY BY SLEEP AND AROUSALBeth Malow; Fiscal Year: 2003..abstract_text> ..
- High Field Neuroimaging of EpilepsyKenneth Laxer; Fiscal Year: 2009..abstract_text> ..
- MAGNETOENCEPHALOGRAM IN EPILEPSYWILLIAM SUTHERLING; Fiscal Year: 2005....
- ONTOGENY OF LIMBIC SEIZURESEdward Bertram; Fiscal Year: 1992..These experiments will examine these critical questions in the ontogeny of partial seizures using the new long term monitoring technology, providing new insights into the mechanisms leading to the chronic epileptic state...
- HULTICHANNEL PARAMETRIC ANALYSIS OF SEIZURE PROPAGATIONGREGORY BERGEY; Fiscal Year: 2002..Understanding the spatiotemporal relationships that produce seizure can provide important insights into epileptogenesis. ..
- INHIBITION IN ENTHORHINAL CORTEX IN CHRONIC EPILEPSYNATHAN FOUNTAIN; Fiscal Year: 2000..The information obtained by these studies will outline the nature of altered inhibition in EC associated with spontaneous seizures and will assist in the development of new and more effective therapies. ..
- TRANSGENIC APPROACHES TO ACETYLCHOLINE RECEPTOR FUNCTIONJim Boulter; Fiscal Year: 1999..The purpose of this part of the proposal is to provide an animal model to analyze the molecular pathology of partial epilepsy, and to offer a paradigm for the development and evaluation of cholinergic therapeutic strategies. ..
- QUANTITATIVE MRI IN EPILEPSYClifford Jack; Fiscal Year: 1999....
- Long-Term Outcomes of Childhood-Onset EpilepsyAnne Berg; Fiscal Year: 2006..This in turn could help lessen the burdens associated with childhood-and adolescent-onset epilepsy for the individual, the family, and society as a whole. ..
- GENETIC EPIDEMIOLOGY OF SEIZURE DISORDERS IN ROCHESTERRuth Ottman; Fiscal Year: 2006..abstract_text> ..
- Quantitative multimodal analyses in pediatric epilepsy surgeryEishi Asano; Fiscal Year: 2008..If funded, the applicant will achieve the necessary training in an excellent environment to develop into an independent investigator. [unreadable] [unreadable]..
- GENETIC EPIDEMIOLOGY OF FAMILIAL EPILEPSYRuth Ottman; Fiscal Year: 2001..g., generalized epilepsy, localization-related epilepsy). ..
- GENETICS OF AD PARTIAL EPILEPSY WITH AUDITORY FEATURESRuth Ottman; Fiscal Year: 2007..abstract_text> ..
- Plasticity of Language Networks in Childhood EpilepsyWILLIAM GAILLARD; Fiscal Year: 2006..Furthermore, patients may be identified and evaluated at the outset of the disease process so that the neuronal response and degree of plasticity may be assessed and monitored. ..
- PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSYAndrew Herzog; Fiscal Year: 2008..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
- CHRONOBIOLOGY OF PARTIAL EPILEPSYMark Quigg; Fiscal Year: 2002..In summary, these studies will provide insight into the chronoblological factors that facilitate partial seizure expression and may provide new perspectives into treatments for poorly controlled partial epilepsy. ..
- Evaluation of models of pharmacoresistant epilepsy.H White; Fiscal Year: 2005..abstract_text> ..
- Validation of rat models for resistant epilepsy therapyWolfgang Loscher; Fiscal Year: 2005..Our goal is to establish standard assays that can be employed by researchers to continue the search for treatments of drug resistant epilepsy. ..
- Gene expression in epileptic cortical dysplasiasImad Najm; Fiscal Year: 2004..This is a unique opportunity to screen large numbers of genes that may be involved in epileptogenesis using samples which are electrophysiologically and pathologically well defined. ..
- PHYSIOLOGY OF APOPTOTIC NEURONAL INJURY IN VITROSteven Rothman; Fiscal Year: 2001..Most important, they will provide direct evidence for the recruitment of apoptotic pathways in ischemic human brain. ..
- THOUGHT DISORDER: A DEVELOPMENTAL DISABILITY IN EPILEPSYRochelle Caplan; Fiscal Year: 2003..Weekly seizure frequency data will be obtained on a monthly basis from the parent during the 2 years. ..
- GENE THERAPY AND SEIZURESThomas J McCown; Fiscal Year: 2011..The present proposed studies will define the most efficacious adeno-associated virus vector which will provide a viable gene therapy treatment for intractable epilepsy. ..
- ROLE OF FDG-PET, 1H-MRSI, AND MSI IN EPILEPSY SURGERYRobert Knowlton; Fiscal Year: 2005....
- A MULTI-CENTER STUDY OF EPILEPSY SURGERYSusan Spencer; Fiscal Year: 2005....
- Pediatric Thought Disorder: Insights from NeuroimagingRochelle Caplan; Fiscal Year: 2006..abstract_text> ..
- Anticipating Seizures in Epileptic NetworksSusan Spencer; Fiscal Year: 2007..Fifteen patients will be studied in the retrospective studies, and 45 patients will be studied in the prospective studies. [unreadable] [unreadable]..
- NEUROBEHAVIORAL FEATURES & MESIAL TEMPORAL LOBE EPILEPSYBruce Hermann; Fiscal Year: 2005..The findings will have potential implications for treatment as well as the understanding of the pathophysiology and natural history of TLE. ..
- NEW STRATEGIES FOR NEOCORTICAL EPILEPSYSteven Rothman; Fiscal Year: 2007..If Peltier devices can control focal seizures in our models, they will be refined for future experiments to investigate their potential role in mapping and controlling epileptogenic neocortex in man. [unreadable] [unreadable]..
- Functional Architecture of Developmental Brain DisorderBernard Chang; Fiscal Year: 2008..By combining training in these two areas, the candidate will gain the experience and skills necessary to transition to an independent career in clinical neuroscience research. [unreadable] [unreadable]..
- Directed Evolution of Adeno-Associated Virus Vectors for Seizure Gene TherapyThomas McCown; Fiscal Year: 2008..If successful, this novel approach could greatly advance the application of gene therapy to the treatment of neurological disorders. [unreadable] [unreadable] [unreadable] [unreadable]..
- Hedgehog, Patched, and Gli in MedulloblastomaHoward Weiner; Fiscal Year: 2007..This system provides a unique opportunity to investigate an in vivo animal model of childhood medulloblastoma, and to determine the roles of Ptc and Gli in tumorigenesis. ..
- Electrocorticographic Study of Categorical Phoneme Perception in the Human TemporEdward Chang; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Improving Learning in MS: A Randomized Clinical TrialNancy Chiaravalloti; Fiscal Year: 2008..In addition, we will be able to draw conclusions regarding the impact of this particular memory remediation program on everyday life from questionnaires completed by the participant and a significant other. [unreadable] [unreadable]..
- Evolution of seizure precursors in refactory epilepsyBrian Litt; Fiscal Year: 2008....
- Cortical Excitability in Cocaine-Dependent SubjectsNashaat Boutros; Fiscal Year: 2006..A normal control group will be included. The TMS measured motor threshold and length of the TMS induced silent periods will be compared between the three groups. ..
- Antiepileptogenic & Disease Modifying Effects of AEDsAsla Pitkanen; Fiscal Year: 2005..abstract_text> ..
- Integration of MSI/fMRI Studies of ReadingAndrew Papanicolaou; Fiscal Year: 2004..Together these efforts will expand the interpretability of imaging data by direct comparison and integration of the techniques and lead to a more elaborated theory of the cerebral mechanisms underlying reading. ..