cerebellar diseases

Summary

Summary: Diseases that affect the structure or function of the cerebellum. Cardinal manifestations of cerebellar dysfunction include dysmetria, GAIT ATAXIA, and MUSCLE HYPOTONIA.

Top Publications

  1. ncbi Reliability and validity of ICARS in focal cerebellar lesions
    Beate Schoch
    Department of Neurosurgery, University of Duisburg Essen, Essen, Germany
    Mov Disord 22:2162-9. 2007
  2. ncbi Recovery of upper limb function after cerebellar stroke: lesion symptom mapping and arm kinematics
    Jurgen Konczak
    Human Sensorimotor Control Laboratory, University of Minnesota, Minneapolis, MN 55455, USA
    Stroke 41:2191-200. 2010
  3. ncbi Cognitive and affective disturbances following focal cerebellar damage in adults: a neuropsychological and SPECT study
    Hanne Baillieux
    Department of Linguistics, Vrije Universiteit Brussel, Belgium
    Cortex 46:869-79. 2010
  4. pmc Vertebral artery dissection and cerebellar infarction following chiropractic manipulation
    W L Chen
    Department of Emergency Medicine, Cathay General Hospital, Institute of Emergency and Critical Care Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
    Emerg Med J 23:e1. 2006
  5. ncbi Cerebellar regions involved in adaptation to force field and visuomotor perturbation
    Opher Donchin
    Dept of Biomedical Engineering, Ben Gurion Univ of the Negev, Be er Sheva 84105, Israel
    J Neurophysiol 107:134-47. 2012
  6. ncbi Mapping of equine cerebellar abiotrophy to ECA2 and identification of a potential causative mutation affecting expression of MUTYH
    Leah S Brault
    Veterinary Genetics Laboratory, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, USA
    Genomics 97:121-9. 2011
  7. ncbi Development and developmental disorders of the human cerebellum
    H J ten Donkelaar
    321 Dept of Neurology, University Medical Centre Nijmegen, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    J Neurol 250:1025-36. 2003
  8. ncbi Role of the cerebellum in eyeblink conditioning
    Vlastislav Bracha
    Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, IA 50011, USA
    Prog Brain Res 143:331-9. 2004
  9. pmc Crossed cerebellar diaschisis in acute stroke detected by dynamic susceptibility contrast MR perfusion imaging
    D D M Lin
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    AJNR Am J Neuroradiol 30:710-5. 2009
  10. ncbi Evaluation of multiple-session delay eyeblink conditioning comparing patients with focal cerebellar lesions and cerebellar degeneration
    Marcus Gerwig
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, D 45147 Essen, Germany
    Behav Brain Res 212:143-51. 2010

Detail Information

Publications230 found, 100 shown here

  1. ncbi Reliability and validity of ICARS in focal cerebellar lesions
    Beate Schoch
    Department of Neurosurgery, University of Duisburg Essen, Essen, Germany
    Mov Disord 22:2162-9. 2007
    To evaluate the therapies for cerebellar diseases appropriate neurological assessment methods to measure severity of ataxia are required...
  2. ncbi Recovery of upper limb function after cerebellar stroke: lesion symptom mapping and arm kinematics
    Jurgen Konczak
    Human Sensorimotor Control Laboratory, University of Minnesota, Minneapolis, MN 55455, USA
    Stroke 41:2191-200. 2010
    ..This study provides a comprehensive assessment of how lesion site and arm dysfunction are associated in the acute stage and outlines the course of upper limb motor recovery for the first 4 months after the infarction...
  3. ncbi Cognitive and affective disturbances following focal cerebellar damage in adults: a neuropsychological and SPECT study
    Hanne Baillieux
    Department of Linguistics, Vrije Universiteit Brussel, Belgium
    Cortex 46:869-79. 2010
    ....
  4. pmc Vertebral artery dissection and cerebellar infarction following chiropractic manipulation
    W L Chen
    Department of Emergency Medicine, Cathay General Hospital, Institute of Emergency and Critical Care Medicine, National Yang Ming University, Taipei, Taiwan, Republic of China
    Emerg Med J 23:e1. 2006
    ..A number of cases of VAD associated with chiropractic cervical manipulation have been reported, but rarely in the emergency medicine literature. We present a case of this rare occurrence, and discuss the diagnostic pitfalls...
  5. ncbi Cerebellar regions involved in adaptation to force field and visuomotor perturbation
    Opher Donchin
    Dept of Biomedical Engineering, Ben Gurion Univ of the Negev, Be er Sheva 84105, Israel
    J Neurophysiol 107:134-47. 2012
    ..The posterolateral cerebellum may process common aspects of both tasks...
  6. ncbi Mapping of equine cerebellar abiotrophy to ECA2 and identification of a potential causative mutation affecting expression of MUTYH
    Leah S Brault
    Veterinary Genetics Laboratory, School of Veterinary Medicine, University of California, Davis, Davis, CA 95616, USA
    Genomics 97:121-9. 2011
    ..This SNP may therefore have a function effect on TOE1, or a regulatory effect on MUTYH by negatively affecting the binding affinity of GATA2...
  7. ncbi Development and developmental disorders of the human cerebellum
    H J ten Donkelaar
    321 Dept of Neurology, University Medical Centre Nijmegen, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    J Neurol 250:1025-36. 2003
    ..In this review the development of the cerebellum and some of its more frequent developmental disorders, such as the Dandy-Walker and related midline malformations, and the pontocerebellar hypoplasias, are discussed...
  8. ncbi Role of the cerebellum in eyeblink conditioning
    Vlastislav Bracha
    Department of Biomedical Sciences, Iowa State University College of Veterinary Medicine, Ames, IA 50011, USA
    Prog Brain Res 143:331-9. 2004
    ..There is also need for the development of new experimental approaches to associative learning in both the nonhuman primate and the human...
  9. pmc Crossed cerebellar diaschisis in acute stroke detected by dynamic susceptibility contrast MR perfusion imaging
    D D M Lin
    Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    AJNR Am J Neuroradiol 30:710-5. 2009
    ....
  10. ncbi Evaluation of multiple-session delay eyeblink conditioning comparing patients with focal cerebellar lesions and cerebellar degeneration
    Marcus Gerwig
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, D 45147 Essen, Germany
    Behav Brain Res 212:143-51. 2010
    ..Intact anterior lobe, which it thought to contribute to CR timing, may explain recovery of disordered timing in focal cerebellar patients...
  11. ncbi Timing of conditioned eyeblink responses is impaired in cerebellar patients
    Marcus Gerwig
    Department of Neurology, University of Duisburg Essen, D 45147 Essen, Germany
    J Neurosci 25:3919-31. 2005
    ..Extracerebellar premotoneuronal disinhibition, however, is another possible explanation for changes in CR timing...
  12. pmc Moving, sensing and learning with cerebellar damage
    Amy J Bastian
    Kennedy Krieger Institute, Department of Neuroscience, The Johns Hopkins School of Medicine, United States
    Curr Opin Neurobiol 21:596-601. 2011
    ..This review covers these and other recent advances, focusing on how cerebellar damage affects human abilities ranging from sensory perception to movement control and motor learning...
  13. ncbi Cerebellar abiotrophy in a family of Border Collie dogs
    J R Sandy
    School of Veterinary Science, University of Melbourne, Australia
    Vet Pathol 39:736-8. 2002
    ..The biochemical basis for this form of cerebellar abiotrophy is unknown, but the lack of disease in other siblings supports an autosomal recessive mode of inheritance...
  14. ncbi Cerebellar white matter injury following systemic endotoxemia in preterm fetal sheep
    J M Dean
    Department of Physiology and Neuroscience, Perinatal Centre, Sahlgrenska Academy, Gothenburg University, Goteborg, Sweden
    Neuroscience 160:606-15. 2009
    ....
  15. ncbi Current advances in lesion-symptom mapping of the human cerebellum
    D Timmann
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45138 Essen, Germany
    Neuroscience 162:836-51. 2009
    ..We conclude that meaningful correlations between lesion site and behavioral data can be obtained in patients with degenerative as well as focal cerebellar disorders...
  16. ncbi The human cerebellum and associative learning: dissociation between the acquisition, retention and extinction of conditioned eyeblinks
    V Bracha
    Division of Neurobiology, Barrow Neurological Institute, 350 W Thomas Rd, Phoenix, AZ, USA
    Brain Res 860:87-94. 2000
    ..This finding suggests that in humans, the acquisition of new and the extinction of previously learned conditioned responses depends on a similar set of cerebellar circuits...
  17. ncbi Prism adaptation during walking generalizes to reaching and requires the cerebellum
    Susanne M Morton
    Kennedy Krieger Institute Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neurophysiol 92:2497-509. 2004
    ..In contrast, prism adaptation during isolated movements of the limbs is probably recalibrated by effector-specific mechanisms. The cerebellum is an essential component in the network for both types of prism adaptation...
  18. pmc Evolutionarily assembled cis-regulatory module at a human ciliopathy locus
    Jeong Ho Lee
    Neurogenetics Laboratory, Howard Hughes Medical Institute HHMI, Department of Neurosciences, University of California, San Diego, CA, USA
    Science 335:966-9. 2012
    ..Hence, during vertebrate evolution of genes involved in ciliogenesis, nonparalogous genes were arranged to a functional gene cluster with shared regulatory elements...
  19. ncbi Neurodevelopmental outcomes in children with cerebellar malformations: a systematic review
    Marie Eve Bolduc
    School of Physical and Occupational Therapy, McGill University, Montreal, Canada
    Dev Med Child Neurol 51:256-67. 2009
    ..In summary, rigorous outcome studies describing the spectrum of disabilities in survivors are urgently needed to accurately delineate the long-term neurodevelopmental consequences of cerebellar malformations...
  20. ncbi The ciliary gene RPGRIP1L is mutated in cerebello-oculo-renal syndrome (Joubert syndrome type B) and Meckel syndrome
    Marion Delous
    Institut National de la Santé et de la Recherche Médicale INSERM U 574, Hopital Necker Enfants Malades, 75015 Paris, France
    Nat Genet 39:875-81. 2007
    ..Our findings show that mutations in RPGRIP1L can cause the multiorgan phenotypic abnormalities found in CORS or MKS, which therefore represent a continuum of the same underlying disorder...
  21. ncbi Polymerase chain reaction (PCR) amplification of parvoviral DNA from the brains of dogs and cats with cerebellar hypoplasia
    Scott J Schatzberg
    Department of Clinical Sciences, Cornell University Hospital for Animals, Cornell University, Ithaca, NY 14853 6401, USA
    J Vet Intern Med 17:538-44. 2003
    ..This study shows that parvoviral DNA can be amplified from feline and canine archival brain tissue and that cerebellar hypoplasia in dogs might be associated with in utero parvovirus infection...
  22. ncbi Cerebellar hemorrhage in the preterm infant: ultrasonographic findings and risk factors
    Catherine Limperopoulos
    Department of Neurology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts, USA
    Pediatrics 116:717-24. 2005
    ..Information is limited, however, on the incidence, topography, and risk factors for CBH in the preterm infant...
  23. ncbi Subclinical cerebellar impairment in the common types of migraine: a three-dimensional analysis of reaching movements
    P S Sandor
    Neurology Department, University Hospitals of Zurich, Switzerland
    Ann Neurol 49:668-72. 2001
    ..These were more pronounced in migraine with than without aura. Whether this reflects involvement of Ca2+ channel genes in the common types of migraine needs to be investigated by genetic analyses...
  24. ncbi Lesion patterns and etiology of ischemia in superior cerebellar artery territory infarcts
    Emre Kumral
    Stroke Unit, Department of Neurology, Faculty of Medicine, Ege University, Izmir, Turkey
    Cerebrovasc Dis 19:283-90. 2005
    ..Diffusion-weighted imaging (DWI) is superior to conventional magnetic resonance imaging for detecting acute small and multiple ischemic lesions...
  25. ncbi Normal cognitive functions in joubert syndrome
    A Poretti
    Department of Pediatric Neurology, University Children s Hospital of Zurich, Switzerland
    Neuropediatrics 40:287-90. 2009
    ..Molecular investigations demonstrated a homozygous mutation in the INPP5E gene. This exceptional observation confirms that normal cognitive functions are possible in JS and corroborates the well known intrafamilial variability...
  26. ncbi Genotype-phenotype correlation in CC2D2A-related Joubert syndrome reveals an association with ventriculomegaly and seizures
    Ruxandra Bachmann-Gagescu
    Division of Genetic Medicine, Department of Pediatrics, University of Washington, Seattle, Washington 98195 6320, USA
    J Med Genet 49:126-37. 2012
    ..CC2D2A mutations are a relatively common cause of JS and also cause Meckel syndrome. The clinical consequences of CC2D2A mutations in patients with JS have been incompletely reported...
  27. ncbi Joubert syndrome and related disorders: spectrum of neuroimaging findings in 75 patients
    A Poretti
    Division of Pediatric Neurology, University Children s Hospital of Zurich, Switzerland
    AJNR Am J Neuroradiol 32:1459-63. 2011
    ..Neuroimaging differences in siblings represent intrafamilial heterogeneity. Due to the absence of a correlation with genotype, neuroimaging findings are of limited value in classifying patients with JSRD...
  28. ncbi Prenatal and neonatal MR imaging findings in oral-facial-digital syndrome type VI
    A Poretti
    Department of Pediatric Neurology, University Children s Hospital of Zurich, Zurich, Switzerland
    AJNR Am J Neuroradiol 29:1090-1. 2008
    ..If the molar tooth sign and a hypothalamic hamartoma are present, prenatal diagnosis of OFDS VI is possible...
  29. pmc Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome
    Madeline A Lancaster
    Laboratory for Neurogenetics, Howard Hughes Medical Institutes, Department of Pediatrics and Neurosciences, Institute for Genomic Medicine, University of California, San Diego, San Diego, California, USA
    Nat Med 17:726-31. 2011
    ..Our findings implicate a defect in Wnt signaling in the cerebellar midline phenotype seen in Joubert syndrome that can be overcome with Wnt stimulation...
  30. pmc Mutations in KIF7 link Joubert syndrome with Sonic Hedgehog signaling and microtubule dynamics
    Claudia Dafinger
    Institute of Human Genetics, Department of Medicine and Centre for Molecular Medicine, University of Cologne, Cologne, Germany
    J Clin Invest 121:2662-7. 2011
    ..Thus, we suggest that modified microtubule stability and growth direction caused by loss of KIF7 function may be an underlying disease mechanism contributing to JBTS...
  31. ncbi Interpeduncular heterotopia in Joubert syndrome: a previously undescribed MR finding
    I Harting
    Department of Neuroradiology, University of Heidelberg Medical School, Heidelberg, Germany
    AJNR Am J Neuroradiol 32:1286-9. 2011
    ..This new imaging feature enlarges the spectrum of brain stem abnormalities in JSRD. In view of the underlying ciliopathy, it seems likely that the interpeduncular heterotopia results from misdirected migration...
  32. pmc The ciliopathies in neuronal development: a clinical approach to investigation of Joubert syndrome and Joubert syndrome-related disorders
    Shifteh Sattar
    Department of Neurosciences and Paediatrics, University of California, San Diego, La Jolla, CA, USA
    Dev Med Child Neurol 53:793-8. 2011
    ..Recognizing the diverse presentations of the ciliopathies and screening strategies following diagnosis is an important part of the treatment plan of children with cilia-related disorders...
  33. ncbi Mutations in the gene encoding the basal body protein RPGRIP1L, a nephrocystin-4 interactor, cause Joubert syndrome
    Heleen H Arts
    Department of Human Genetics, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, 6500 HB Nijmegen, The Netherlands
    Nat Genet 39:882-8. 2007
    ..This work identifies RPGRIP1L as a gene responsible for JBTS and establishes a central role for cilia and basal bodies in the pathophysiology of this disorder...
  34. ncbi Ipsidirectional impairment of prism adaptation after unilateral lesion of anterior cerebellum
    L Pisella
    Espace et Action, INSERM, Universite Claude Bernard Lyon I, Institut Federatif des Neurosciences de Lyon, Mouvement et Handicap, Lyon, France
    Neurology 65:150-2. 2005
    ..He adapted to rightward but not leftward prisms, independent of which hand was used during exposure. This suggests a role of anterior cerebellar cortex in the computation or compensation of ipsidirectional visual error...
  35. ncbi The molar tooth sign: a new Joubert syndrome and related cerebellar disorders classification system tested in Egyptian families
    M S Zaki
    Clinical Genetics Department, National Research Centre, Neuromotor Institute, Cairo, Egypt
    Neurology 70:556-65. 2008
    ..Each family could be classified into one of the four subtypes. This classification may thus be useful in the evaluation of patients with JSRD...
  36. ncbi The ciliopathy-associated protein homologs RPGRIP1 and RPGRIP1L are linked to cilium integrity through interaction with Nek4 serine/threonine kinase
    Karlien L M Coene
    Department of Human Genetics 855, Radboud University Nijmegen Medical Centre, PO Box9101, 6500 HB Nijmegen, The Netherlands
    Hum Mol Genet 20:3592-605. 2011
    ..Our data are in line with previously established roles in the cilium of other members of the Nek protein family and define NEK4 as a ciliopathy candidate gene...
  37. ncbi Cerebellar cortical abiotrophy in Lagotto Romagnolo dogs
    T S Jokinen
    Department of Clinical Veterinary Sciences, University of Helsinki, PO Box 57, 00014 Helsinki, Finland
    J Small Anim Pract 48:470-3. 2007
    ..The second case had degenerative changes in both Purkinje and granular cell layers. The clinical picture was similar in both cases presented, although the severity of the signs of cerebellar dysfunction varied...
  38. ncbi Role of MR imaging in prenatal diagnosis of pregnancies at risk for Joubert syndrome and related cerebellar disorders
    S N Saleem
    Radiology Department, Kasr Al Ainy Hospital, Cairo University, Cairo, Egypt
    AJNR Am J Neuroradiol 31:424-9. 2010
    ..JSRD are rare autosomal recessive brain malformations. We hypothesized that MR imaging can assess fetuses at risk for JSRD and might influence their diagnoses...
  39. ncbi Psychopathology in patients with degenerative cerebellar diseases: a comparison to Huntington's disease
    Iracema Leroi
    Program in Cellular and Molecular Medicine, Department of Psychiatry and Behavioral Sciences, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Am J Psychiatry 159:1306-14. 2002
    This study estimated the psychiatric morbidity of patients with degenerative cerebellar diseases.
  40. ncbi Oligophrenin 1 mutations frequently cause X-linked mental retardation with cerebellar hypoplasia
    G Zanni
    University of Paris 5 René Descartes, INSERM Unité 567, CNRS UMR8104, Paris, France
    Neurology 65:1364-9. 2005
    ....
  41. ncbi Intracerebellar hemorrhage in premature infants: sonographic detection and outcome
    Hanna Müller
    Division of Neonatology, Department of Pediatrics, University of Heidelberg, Germany
    J Perinat Med 35:67-70. 2007
    ..Intracerebellar hemorrhage is a rarely confirmed diagnosis in preterm infants in comparison to peri-/intraventricular hemorrhage. This study evaluates the incidence of intracerebellar hemorrhage and neurological outcome in preterm infants...
  42. ncbi Trace eyeblink conditioning in human subjects with cerebellar lesions
    M Gerwig
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45147, Essen, Germany
    Exp Brain Res 170:7-21. 2006
    ....
  43. ncbi Ophthalmological findings in Joubert syndrome
    V Sturm
    Department of Ophthalmology, University Hospital of Zurich, Zurich, Switzerland
    Eye (Lond) 24:222-5. 2010
    ..It has been associated with ocular and oculomotor abnormalities. The aim of our study was to extend the ophthalmic knowledge in JS and to add new findings...
  44. ncbi [Pulmonary nocardiasis with abscesses spreading to cerebrum, cerebellum and orbits]
    M Borchers
    Medizinische Klinik des Evangelischen Krankenhauses Witten
    Dtsch Med Wochenschr 131:1085-8. 2006
    ..She was known to have chronic obstructive pulmonary disease treated with corticoids given systemically and by inhalation. She was a heavy smoker...
  45. ncbi Lack of Mid1, the mouse ortholog of the Opitz syndrome gene, causes abnormal development of the anterior cerebellar vermis
    Alessio Lancioni
    Telethon Institute of Genetics and Medicine, Naples, Italy
    J Neurosci 30:2880-7. 2010
    ..This animal model provides a tool for additional in vivo studies of the physiological and pathological role of the Mid1 gene and a system to investigate the development and function of anterior cerebellar domains...
  46. ncbi Uteroplacental inflammation results in blood brain barrier breakdown, increased activated caspase 3 and lipid peroxidation in the late gestation ovine fetal cerebellum
    Lisa C Hutton
    Fetal and Neonatal Research Group, Department of Physiology, Monash University Clayton Campus, Melbourne, Australia
    Dev Neurosci 29:341-54. 2007
    ..These effects may account for some of the learning and motor deficits that emerge in neonates from pregnancies compromised by infection...
  47. ncbi Successful therapy combined with surgery for severe post-transplant nocardiosis
    S M Kayacan
    Department of Internal Medicine, Istanbul School of Medicine, Turkey
    J Nephrol 14:304-6. 2001
    ..Co-trimoxazole was continued for six months then withdrawn. Graft dysfunction was not observed. Early medical and surgical interventions may be life-saving in this potentially lethal disease...
  48. ncbi Patients with chronic focal cerebellar lesions show no cognitive abnormalities in a bedside test
    Stefanie Richter
    Department of Neurology, University of Duisberg Essen, Essen, Germany
    Neurocase 13:25-36. 2007
    ..No obvious cognitive deficits appeared to be present in chronic cerebellar patients as assessed by a bedside screening test...
  49. ncbi Crossed cerebellar diaschisis: a positron emission tomography study with L-[methyl-11C]methionine and 2-deoxy-2-[18F]fluoro-D-glucose
    Katsufumi Kajimoto
    Department of Nuclear Medicine and Tracer Kinetics, Osaka University Graduate School of Medicine, Suita, Japan
    Ann Nucl Med 21:109-13. 2007
    ..We examined whether L-[methyl-11C]methionine (MET) uptake is affected in CCD...
  50. ncbi MR evaluation of crossed and uncrossed cerebral-cerebellar diaschisis
    A Chakravarty
    Division of Neurology, Vivekananda Institute of Medical Sciences, Calcutta
    Acta Neurol Scand 108:60-5. 2003
    ..Functional neuroimaging studies in support of the concept of CCD and ICD have been critically reviewed in the light of the morphological changes demonstrated in the cases cited herein...
  51. ncbi A clinical study of 31 individuals with midline facial defects with hypertelorism and a guideline for follow-up
    Vera Lucia Gil-da-Silva-Lopes
    Departamento de Genética Médica, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas, Campinas, SP, Brasil
    Arq Neuropsiquiatr 65:396-401. 2007
    ..Isolated FNM may have involvement of environmental components in some cases; the possibility of a syndromic picture should be extensive investigated. Follow-up of such patients must include the examinations herein performed...
  52. ncbi Acute cerebellitis presenting as tumor. Report of two cases
    Nelly Amador
    Departments of Neurological Surgery, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Neurosurg 107:57-61. 2007
    ..The literature is reviewed and therapy considerations are emphasized...
  53. ncbi Hypomyelination with atrophy of the basal ganglia and cerebellum: follow-up and pathology
    M S van der Knaap
    Department of Child Neurology, VU University Medical Center, Amsterdam, The Netherlands
    Neurology 69:166-71. 2007
    ..Only a few patients have been described. We report on 11 additional patients and new MRI findings and provide histopathologic confirmation of the MRI interpretation...
  54. ncbi Cerebellar skew deviation and the torsional vestibuloocular reflex
    Agnes M F Wong
    Division of Neurology, Department of Ophthalmology and Vision Science, University Health Network, University of Toronto, Ontario, Canada
    Neurology 65:412-9. 2005
    ....
  55. ncbi Predominant dystonia with marked cerebellar atrophy: a rare phenotype in familial dystonia
    J Hagenah
    Neurology 68:2157; author reply 2157-8. 2007
  56. ncbi Diffuse craniospinal choroid plexus papilloma with involvement of both cerebellopontine angles
    F Doglietto
    Institute of Neurosurgery, Catholic University School of Medicine, 00168 Rome, Italy
    Neurology 65:842. 2005
  57. ncbi Structural and functional MRIs disclose cerebellar pathologies in idiopathic downbeat nystagmus
    K Hufner
    Department of Neurology, Klinikum Grosshadern, Neurologisches Forschungshaus, Munich, Germany
    Neurology 69:1128-35. 2007
    ..Forty percent of patients with DBN are classified as having idiopathic DBN, because no underlying pathology can be demonstrated by conventional MRI or laboratory tests...
  58. ncbi Saccades in children with spina bifida and Chiari type II malformation
    M S Salman
    Division of Neurology, Hospital for Sick Children, Ontario, Canada
    Neurology 64:2098-101. 2005
    ..Saccades are essential for optimal visual function. Chiari type II malformation (CII) is a congenital anomaly of the cerebellum and brainstem, associated with spina bifida...
  59. doi Dissociation between canal- and otolithfunction in cerebellar atrophy
    Sarah Marti
    J Neurol 255:769-71. 2008
  60. doi Cerebellar T2 hyperintensities in a patient with tremor
    Menachem Sadeh
    Department of Neurology, Wolfson Medical Center, Holon, Israel
    Neurology 70:578. 2008
  61. ncbi Postpartum cerebellar infarction and haemolysis, elevated liver enzymes, low platelet (HELLP) syndrome
    C Altamura
    Clinica Neurologica, Universita Campus BioMedico, Rome, Italy
    Neurol Sci 26:40-2. 2005
    ..This case report gives evidence of the importance of considering the different risk factors involved in stroke occurrence during pregnancy...
  62. ncbi Trace eyeblink conditioning in patients with cerebellar degeneration: comparison of short and long trace intervals
    M Gerwig
    Department of Neurology, University of Duisburg Essen, Hufelandstrasse 55, 45147 Essen, Germany
    Exp Brain Res 187:85-96. 2008
    ..Using a long trace interval, the cerebellum appears to be less important...
  63. ncbi Radiologically atypical congenital posterior fossa dermoid cyst presenting late in life
    David Wallace
    Department of Neurosurgery, Royal Melbourne Hospital, Parkville, Victoria, Australia
    J Clin Neurosci 15:835-8. 2008
    ..Pathological study revealed a dermoid cyst. Post-operatively, her hydrocephalus persisted and a ventriculo-atrial shunt was inserted with excellent functional recovery...
  64. ncbi Cerebellar vascular hamartoma in a British Shorthair cat
    Catherine E Stalin
    Department of Veterinary Medicine, Cambridge University, Madingley Road, Cambridge CB3 0ES, United Kingdom
    J Feline Med Surg 10:206-11. 2008
    ..A lesion of this type represents a previously unreported differential diagnosis for central nervous system lesions in young cats...
  65. ncbi [Thunderclap headache caused by cerebellar infarction]
    G Gossrau
    Universitätsschmerzzentrum, Universitätsklinikum der TU Dresden, Fetscherstr 74, 01309, Dresden, Deutschland
    Schmerz 22:82-6. 2008
    ....
  66. ncbi The role of posterior fossa decompression in acute cerebellitis
    S de Ribaupierre
    Departement de Neurochirurgie, CHUV, Lausanne, Switzerland
    Childs Nerv Syst 21:970-4. 2005
    ..We present two cases of children who were diagnosed with cerebellitis with acute cerebellar swelling. This rare pathology is potentially fatal, and no clear treatment guidelines are described in the literature...
  67. ncbi Early pathological changes in the cerebellum of patients with pure cerebellar syndrome demonstrated by diffusion-tensor imaging
    Bora Yoon
    Department of Neurology, Catholic University of Korea College of Medicine, Hangnam St Mary s Hospital, 505 Banpo Dong, Seocho Gu, Seoul 137 701, Korea
    Eur Neurol 56:166-71. 2006
    ..Therefore, DTI may be superior to conventional MRI in the evaluation of early pathological changes in patients with sporadic cerebellar ataxia...
  68. ncbi X-linked oligophrenic vermian dysgenesis: syndromic vs non-syndromic X-linked mental retardation?
    Joseph J Higgins
    Neurology 65:1346-7. 2005
  69. ncbi Anterior and posterior inferior cerebellar artery infarction with sudden deafness and vertigo
    Takenobu Murakami
    Department of Neurology, Tottori Prefectural Central Hospital, Tottori, Japan Department of Neurology, Institute of Neurological Sciences, Faculty of Medicine, Tottori University, Nishimachi 36 1, Yonago 683 8504, Japan
    J Clin Neurosci 13:1051-4. 2006
    ..Neuroimaging, including magnetic resonance imaging, is strongly recommended for patients with sudden deafness and vertigo to exclude infarction of the vertebral-basilar artery territory...
  70. ncbi Predominant dystonia with marked cerebellar atrophy: a rare phenotype in familial dystonia
    I Le Ber
    INSERM U679, Département de génétique, cytogénétique et embryologie, France
    Neurology 67:1769-73. 2006
    ..Dystonia syndromes constitute a heterogeneous group of phenotypes that may be caused by different heredodegenerative, metabolic, or genetic diseases...
  71. ncbi [Cerebellar infarction: analysis of 151 patients]
    Jefferson Rosi
    Hospital Sao Joaquim, Real e Benemérita Associação Portuguesa de Beneficência, Sao Paulo, Brazil
    Arq Neuropsiquiatr 64:456-60. 2006
    ..Magnetic resonance image was the best diagnostic form for cerebellar lesions, however computerized tomography could show cerebellar infarction in 68 patients (78%)...
  72. ncbi [Cerebellar abscess--unusual reason for ataxia in an alcoholic patient]
    Lausanne P Carron
    Service de Medecine Interne, Departement de Medecine, CHUV, Lausanne
    Praxis (Bern 1994) 95:1085-9. 2006
    ..We describe here a differential diagnosis of an acute ataxia as well as the cerebral abscess mechanisms and causes...
  73. ncbi Cerebellar involvement in midline facial defects with ocular hypertelorism
    Silvyo David Araújo Giffoni
    Departamento de Genética Médica, Faculdade de Ciencias Medicas, Universidade Estadual de Campinas UNICAMP, Campinas SP, Brazil
    Cleft Palate Craniofac J 43:466-70. 2006
    ..Twenty-four patients were evaluated to better characterize neurological and neuroradiological aspects of midline facial defects with ocular hypertelorism...
  74. ncbi [Atypical monoclonal plasma cell hyperplasia. Infiltration of ZNS]
    A Viehover
    Abteilung Neurologie, Neurologische Klinik, Universitatsklinikum Heidelberg, Im Neuenheimer Feld 400, 69120 Heidelberg, Germany
    Nervenarzt 77:1495-500. 2006
    ..We report on an atypical monoclonal plasma cell hyperplasia with bilateral occipital and cerebellar involvement in a 38-year-old woman. The diagnosis was confirmed by brain biopsy immunohistochemical and molecular tests...
  75. ncbi Measuring brain stem and cerebellar damage in parkinsonian syndromes using diffusion tensor MRI
    C R V Blain
    King s College London, Institute of Psychiatry, MRC Centre for Neurodegeneration, Department of Clinical Neuroscience, London, UK
    Neurology 67:2199-205. 2006
    ....
  76. ncbi Deep brain reversible encephalopathy: association with secondary antiphospholipid antibody syndrome
    T Parikh
    Department of Radiology, Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY 10467, USA
    AJNR Am J Neuroradiol 28:76-8. 2007
    ..The patient presented with acute right cerebellar infarction and clinical and imaging evidence of brain stem and bilateral thalamic encephalopathy that resolved completely...
  77. ncbi Anterior inferior cerebellar artery infarction presenting with sudden hearing loss and vertigo
    Eun Jin Son
    Department of Otorhinolaryngology, National Medical Center, Seoul, Korea
    Laryngoscope 117:556-8. 2007
    ..AICA infarction may present without obvious neurologic deficits, and an imaging study is advised in patients at high risk for vascular accidents...
  78. ncbi Upside down reversal of vision due to an isolated acute cerebellar ischemic infarction
    A Horga Hernández
    J Neurol 253:953-4. 2006
  79. ncbi Crossed cerebellar atrophy of prenatal onset
    F Gallini
    Department of Pediatrics, Neonatal Unit, Catholic University, Largo F Vito 1, Rome 00136, Italy
    Childs Nerv Syst 22:734-6. 2006
    ..It was also reported in preterm infants after perinatal or postnatal contralateral supratentorial lesions...
  80. ncbi Diagnostic approach to cerebellar disease in children
    Stefano D'Arrigo
    Department of Pediatric Neurology, Istituto Neurologico C Besta, Milan, Italy
    J Child Neurol 20:859-66. 2005
    ..Subsequent investigations should be suggested by the neuroradiologic and clinical peculiarities of each case...
  81. ncbi Cerebellar infarction in the territory of the medial branch of the superior cerebellar artery
    Sung Il Sohn
    Department of Neurology, Keimyung University School of Medicine, Daegu, South Korea
    Neurology 66:115-7. 2006
    ..Cerebellar dysarthria was found in 8 patients. Eight patients had a mild unilateral limb ataxia. These findings emphasize that MSCA territory cerebellar infarction presented with the prominent gait ataxia and cerebellar dysarthria...
  82. ncbi Impaired working-memory after cerebellar infarcts paralleled by changes in BOLD signal of a cortico-cerebellar circuit
    B Ziemus
    Department of Neurology, University of Regensburg, Germany
    Neuropsychologia 45:2016-24. 2007
    ..We conclude that cerebellar lesions affect remote cortical regions that are part of a putative cortico-cerebellar network...
  83. ncbi Brain stem and cerebellar findings in Joubert syndrome
    Ibrahim A Alorainy
    Department of Radiology and Medical Imaging, King Khalid University Hospital, King Saud University, Riyadh, Saudi Arabia
    J Comput Assist Tomogr 30:116-21. 2006
    ..Awareness of the clinical and neuroimaging findings in Joubert syndrome and maintenance of a high index of suspicion are essential to correctly diagnose this rare congenital malformation...
  84. ncbi Eye movement abnormalities in stiff person syndrome
    John R Economides
    Beckman Vision Center, University of California, San Francisco, CA 94143 0730, USA
    Neurology 65:1462-4. 2005
    ..There was no evidence of ocular myasthenia, indicating that abnormalities of ocular motor function can occur as a primary manifestation of SPS, perhaps from depletion of GABA...
  85. doi Vertebral artery origin thrombus in a patient with cerebellar infarct
    D Eric Searls
    Cerebrovascular Division, Department of Neurology, Palmer 127, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Brookline, MA 02215, USA
    Arch Neurol 65:1386-7. 2008
  86. ncbi Crossed cerebral - cerebellar diaschisis: MRI evaluation
    A Chakravarty
    Department of Neurology, Vivekananda Institute of Medical Sciences, Calcutta, India
    Neurol India 50:322-5. 2002
    ..These observations provide morphological evidence of the phenomenon of crossed cerebral-cerebellar diaschisis (CCD). Functional neuroimaging studies in support of the concept of CCD has been critically reviewed...
  87. ncbi [Vacuolar leucoencephalopathy induced by heroin: 4 cases]
    S Koussa
    Service de Neurologie, Hospital Hotel Dieu de France, Faculte de Medicine, Beyrouth, Liban
    Rev Neurol (Paris) 158:177-82. 2002
    ..The pathophysiology is unknown and seems different from post-anoxic leucoencephalopathy. The disease is usually progressive leading sometimes to death, but some cases show slow recovery...
  88. ncbi MRI findings in acute cerebellitis
    Y De Bruecker
    Department of Radiology, University Hospitals Gasthuisberg, Herestraat 49, 3000 Leuven, Belgium
    Eur Radiol 14:1478-83. 2004
    ..In atypical clinical presentation, MR imaging can lead to the diagnosis. MR imaging findings have, however, no prognostic value...
  89. ncbi Crossed cerebellar atrophy in patients with precocious destructive brain insults
    Ricardo A Teixeira
    Department of Neurology, FCM UNICAMP, Campinas, CEP 13083 970, SP, Brazil
    Arch Neurol 59:843-7. 2002
    ..To analyze the frequency and pathogenetic factors of crossed cerebellar atrophy (CCA) in adult patients with epilepsy secondary to destructive brain insults of early development...
  90. ncbi Bilateral haemorrhagic cerebellar infarction following honey bee sting
    R Bhat
    Department of Medicine, Kasturba Medical College, Manipal, Karnataka
    J Assoc Physicians India 50:721-2. 2002
  91. ncbi Giant cerebellar tuberculoma mimicking a malignant tumour
    S I Poonnoose
    Department of Neurological Sciences, Christian Medical College and Hospital, 632004 Vellore, India
    Neuroradiology 46:136-9. 2004
    ..We highlight the need to integrate different imaging modalities in arriving at a diagnosis of an intracranial mass and discuss atypical features of intracranial tuberculomas...
  92. ncbi Cerebellar symptoms heralding bilirubin encephalopathy in Crigler-Najjar syndrome
    Brahim Tabarki
    Service de Pediatrie, Hôpital Farhat Hached, Sousse, Tunisia
    Pediatr Neurol 27:234-6. 2002
    ..The patient improved slowly with the duration of phototherapy. Cerebellar symptoms can be the initial manifestation of kernicterus in children with Crigler-Najjar syndrome type I...
  93. ncbi [The megadolichobasilar artery--a clinical chameleon]
    R Dziewas
    Klinik und Poliklinik fur Neurologie, Universitatsklinikum Munster
    Nervenarzt 74:172-4. 2003
    ..The article reviews the great variety of clinical symptoms caused by megadolichobasilar artery and discusses important therapeutic options...
  94. ncbi Quantification of brain damage in cerebrotendinous xanthomatosis with magnetization transfer MR imaging
    Matilde Inglese
    Neuroimaging Research Unit, Department of Neuroscience, Milan, Italy
    AJNR Am J Neuroradiol 24:495-500. 2003
    ....
  95. ncbi The mechanisms of recovery from cerebellar infarction: an fMRI study
    Keiko Kinomoto
    Department of Speech Physiology, Graduate School of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 0033, Japan
    Neuroreport 14:1671-5. 2003
    ....
  96. ncbi Vertigo secondary to isolated PICA insufficiency: successful treatment with balloon angioplasty
    Robert A Koenigsberg
    Department of Radiologic Sciences, Drexel University College of Medicine, Philadelphia, Pennsylvania 19106, USA
    Surg Neurol 60:306-10. 2003
    ..We report a case where a nondominant isolated vertebral artery, which terminated in PICA, was stenotic. This resulted in brainstem-lower cerebellar ischemia, corrected with balloon angioplasty...
  97. ncbi Cerebellitis in an adult with abnormal magnetic resonance imaging findings prior to the onset of ataxia
    Kirsten L Gruis
    Department of Neurology and Radiology, University of Michigan, Ann Arbor 48109, USA
    Arch Neurol 60:877-80. 2003
    ..This has resulted in the use of other imaging modalities, such as single-photon emission computed tomography, to aid diagnosis...
  98. ncbi Distal myopathy with rimmed vacuoles and cerebellar atrophy
    Hajnalka Merkli
    Department of Neurology, Faculty of Medicine, University of Pecs, Pecs, H 7623, Hungary
    Pathol Oncol Res 12:115-7. 2006
    ..Muscle biopsy resulted in myopathic changes with rimmed vacuoles. Brain MRI scan showed cerebellar atrophy. This case demonstrates a rare association of distal myopathy and cerebellar atrophy...
  99. ncbi Bilateral anterior inferior cerebellar artery territory brachium pontis infarcts of probable hemodynamic cause
    Roger Kalla
    Department of Neurology, Ludwig Maximilian University, Klinikum Grosshadern, Munich, Germany
    Eur Neurol 51:233-5. 2004
  100. ncbi Pure post-stroke cerebellar cognitive affective syndrome: a case report
    K S Paulus
    Institute of Clinical Neurology, University of Sassari, Viale San Pietro 10, I 07100, Sassari, Italy
    Neurol Sci 25:220-4. 2004
    ..Auditory event-related potentials showed abnormal P300. These data suggest a pure "cerebellar cognitive affective syndrome"and strengthen the hypothesis of cerebellar cognitive function modulation...
  101. ncbi [Lhermitte-Duclos disease in a ten-year-old child: clinical follow-up and neuroimaging data from birth]
    A Verdu
    Unidad de Neuropediatria, Hospital Virgen de la Salud, Toledo
    Rev Neurol 27:597-600. 1998
    ..Lhermitte-Duclos disease is a rare lesion characterized by enlarged cerebellar folia containing abnormal ganglion cells. It typically affects young adults, and reports in the pediatric age are exceptional...

Research Grants35

  1. Cognitive Effects of Cerebellar Lesions in Humans
    JEREMY SCHMAHMANN; Fiscal Year: 2006
    ..This study has implications for the recognition and treatment of disorders of higher order function in cerebellar patients. [unreadable] [unreadable]..
  2. Principles of Therapy in Cerebellar Disease: Explorations in Ion Channel Mutants
    JOHN SAMUEL STAHL; Fiscal Year: 2013
    ....
  3. Regulation of Ptf1a in the Developing Nervous System
    David M Meredith; Fiscal Year: 2010
    ..Furthermore, the advancement in our understanding of how spinal neurons are formed should accelerate the progress in treating spinal cord trauma. ..
  4. Calcium-activated potassium currents in cerebellar Purkinje neurons
    MARK DANIEL BENTON; Fiscal Year: 2011
    ..Our goal is to understand how the electrical activity in Purkinje neurons is regulated, which promises to provide insight into therapeutic treatments for cerebellar disorders.) ..
  5. Mechanisms Underlying the Cerebellar Contribution to Autism in Mouse Models of Tu
    Peter T Tsai; Fiscal Year: 2013
    ..This mentored award will provide Dr. Tsai a structured, productive training experience that will bolster his transition to becoming an independent physician-scientist. ..
  6. CELLULAR ANALYSIS OF THE VESTIBULO-OCULAR REFLEX
    Sascha du Lac; Fiscal Year: 2013
    ....
  7. Functional Domain of the Cerebellum in Motor Learning
    Richard Ivry; Fiscal Year: 2012
    ..The results should be of clinical relevance, allowing therapists to design rehabilitation programs that are tailored to either target or minimize impaired functional capabilities. ..
  8. Disorders of Emotional Communication in Patient with Cerebellar Dysfunction
    Kenneth M Heilman; Fiscal Year: 2013
    ..abstract_text> ..
  9. SIGNAL ANALYSIS OF CEREBELLAR CORTICAL NEURONS
    PETER VAN KAN; Fiscal Year: 1990
    ..basic information concerning the control mechanisms of the cerebellum is needed to obtain insights into cerebellar diseases that lead to dysmetria, a movement disorder characterized by the inability to produce goal directed ..
  10. Genetic Analysis of Roof Plate Function in the CNS
    Kathleen Millen; Fiscal Year: 2008
    ....
  11. Patient-Oriented Research in Recessive Pediatric Brain Diseases
    Joseph Gleeson; Fiscal Year: 2008
    ....
  12. INTERMEDIATE CEREBELLUM IN ADAPTIVE REFLEX CONTROL
    Vlastislav Bracha; Fiscal Year: 2010
    ....
  13. Varenicline and Smoking Cessation in Schizophrenia
    SEYYED HOSSEIN FATEMI; Fiscal Year: 2010
    ..Such outcomes will be significant, because they will offer a new treatment for smoking cessation in this vulnerable population. ..
  14. Prenatal Virally Induced Brain Disorder in Mouse
    SEYYED FATEMI; Fiscal Year: 2009
    ..In addition, it is expected that the results will provide clues that will lead to fundamental advances in our knowledge of the pathogenesis of schizophrenia and, therefore, of how it can be prevented and treated. ..
  15. Vestibulocerebellar function in channelopathy mutants
    John Stahl; Fiscal Year: 2004
    ..Thus, the insights into normal cerebellar function generated by this study should also advance our understanding of mechanisms of heritable neurological disease. ..
  16. FUNCTIONAL STUDIES OF TOPOISOMERASE I
    Eric Rubin; Fiscal Year: 2002
    ..Collectively, these studies should provide information valuable not only for understanding the cellular role of topoisomerase I but also for elucidating the cytotoxic mechanisms of camptothecin. ..
  17. Functional studies of the top 1-binding protein topors
    Eric Rubin; Fiscal Year: 2006
    ..The proposed experiments should significantly increase current knowledge regarding the function of topors and may lead to new strategies in the prevention and treatment of cancer [unreadable] [unreadable]..
  18. Conference on the Diagnosis of Multiple System Atrophy
    Sid Gilman; Fiscal Year: 2006
    ..This conference will assist with early diagnosis by developing new guidelines for diagnosis using newly available imaging and neuropathological criteria. [unreadable] [unreadable] [unreadable]..
  19. NEURONAL INTEGRATION IN CEREBELLAR SYSTEMS
    Vlastislav Bracha; Fiscal Year: 2004
    ....
  20. INTELLIGIBILITY ASSESSMENT IN DYSARTHRIA
    Raymond Kent; Fiscal Year: 2005
    ..The data on dysarthria will be integrated with data on speech development and normal adult speech in a neural network model of speech production that is based on internal models of auditory and articulatory representations of speech. ..
  21. Molecular Mechanisms of Neuronal Migration
    Joseph Gleeson; Fiscal Year: 2006
    ..2) DCX and LIS1 function to regulate nuclear movement during neuronal migration. 3) DCX is regulated by cdk5 during neuronal migration. ..
  22. Advances in Midbrain/Hindbrain Malformations
    Joseph Gleeson; Fiscal Year: 2005
    ..The information content will be made available on the Internet. Thus this Meeting will serve as a resource for both the scientific and lay community throughout the world. ..
  23. Perceptual and Decisional Processes in Categorization
    W Maddox; Fiscal Year: 2006
    ..Project 4 extends the studies in Project I - 3 to an explicit decision criterion task where observers adjust an observable decision criterion on each trial. These data are useful for testing learning models. ..
  24. Molecular Foundations of the Myoclonus-Dystonia Syndrome
    Mark leDoux; Fiscal Year: 2006
    ..We hypothesize that epsilon sarcoglycan co-localizes with GABA receptors opposite GABAergic terminals in the central nervous system. ..
  25. Zic3 and the Control of Body Pattern Formation
    STEPHANIE WARE; Fiscal Year: 2005
    ..Through a combination of supervised research, scientific interchange, and selected coursework within this environment, the candidate will obtain the training necessary to transition to an independent investigator. ..
  26. Mutant Gene Identification in the Dystonic Rat
    Mark leDoux; Fiscal Year: 2008
    ..Patients with dystonia will be screened for mutations in the human homologue. These proposed studies will likely increase our understanding of both dystonia and olivocerebellar motor systems. ..
  27. EYELID SENSORIMOTOR NETWORKS
    Mark leDoux; Fiscal Year: 2003
    ..abstract_text> ..
  28. Semantic Memory and MRI Volumetrics in Epilepsy
    Brian Bell; Fiscal Year: 2005
    ..abstract_text> ..
  29. TETRAHYDROISOQUINOLINES AND PARKINSON'S DISEASE
    Mark leDoux; Fiscal Year: 2006
    ..Evolution may have not provided neurons with mechanisms to prevent accumulation of these by-products of normal metabolism and, as a consequence, susceptible neuronal populations may slowly undergo apoptotic death in the elderly. ..
  30. Mouse models of human cerebellar malformations
    Kathleen Millen; Fiscal Year: 2008
    ..This information is critical to the identification of additional malformation loci. ..
  31. MOLECULAR PATHOGENESIS OF FELINE SPINAL MUSCULAR ATROPHY
    JOHN FYFE; Fiscal Year: 2002
    ..Initial candidate genes will be those implicated in human SMA, but otherwise a comparative positional-candidate gene approach will be taken. ..
  32. Molecular Mechanism of Polarized Cubilin Expression
    JOHN FYFE; Fiscal Year: 2004
    ..Results of these efforts are expected to open a window onto a new aspect of nutrient absorption and membrane receptor biology. ..
  33. Outcomes of Perinatal Stroke
    Meredith Golomb; Fiscal Year: 2008
    ..During the last year of the study, she plans to apply for an R01 grant to set up a pilot clinical trial. [unreadable] [unreadable]..