Genomes and Genes
reflex sympathetic dystrophy
Summary: A syndrome characterized by severe burning pain in an extremity accompanied by sudomotor, vasomotor, and trophic changes in bone without an associated specific nerve injury. This condition is most often precipitated by trauma to soft tissue or nerve complexes. The skin over the affected region is usually erythematous and demonstrates hypersensitivity to tactile stimuli and erythema. (Adams et al., Principles of Neurology, 6th ed, p1360; Pain 1995 Oct;63(1):127-33)
Publications229 found, 100 shown here
- A controlled pilot study of the utility of mirror visual feedback in the treatment of complex regional pain syndrome (type 1)C S McCabe
The Royal National Hospital for Rheumatic Diseases, Upper Borough Walls, Bath BA1 1RL, UK
Rheumatology (Oxford) 42:97-101. 2003..We assessed mirror visual feedback (MVF) to test the hypothesis that incongruence between motor output and sensory input produces complex regional pain syndrome (CRPS) (type 1) pain...
- Bilateral motor cortex disinhibition in complex regional pain syndrome (CRPS) type I of the handP Schwenkreis
Department of Neurology, Ruhr University Bochum, BG Kliniken Bergmannsheil, Bochum, Germany
Neurology 61:515-9. 2003..Its features include pain, edema, autonomic dysfunction, movement disorder, and trophic changes. CNS involvement is suggested by the symptoms, but the pathophysiology of CRPS I is unknown...
- Multiplex bead array assay for detection of 25 soluble cytokines in blister fluid of patients with complex regional pain syndrome type 1Claudia Heijmans-Antonissen
Department of Anaesthesiology, Erasmus MC, P O Box 2040, 3000 CA Rotterdam, The Netherlands
Mediators Inflamm 2006:28398. 2006..Ten representative cytokines were detectable. However, detection levels and amounts measured are at least 3 times higher in the multiplex-25 array assay than in the ELISA assays used simultaneously for the measurement of cytokines...
- Systemic inflammatory mediators in post-traumatic complex regional pain syndrome (CRPS I) - longitudinal investigations and differences to control groupsChristian Schinkel
Berufsgenossenschaftliche Kliniken Bergmannsheil, Department of Surgery, Ruhr University, Bochum, Germany
Eur J Med Res 14:130-5. 2009..Some studies investigated the role inflammatory mediators and cytokines; however, few longitudinal studies exist and control groups except healthy controls were not investigated yet...
- Biopsychosocial complexity is correlated with psychiatric comorbidity but not with perceived pain in complex regional pain syndrome type 1 (algodystrophy) of the kneeAurélie Vouilloz
Clinique Romande de Réadaptation SuvaCare, avenue Grand Champsec 90, 1951 Sion, Switzerland
Joint Bone Spine 78:194-9. 2011..characteristics of patients suffering from complex regional pain syndrome type 1 ([CRPS], also known as reflex sympathetic dystrophy or algodystrophy) of the knee with those of a matched group of patients experiencing post-traumatic ..
- The effect of tactile discrimination training is enhanced when patients watch the reflected image of their unaffected limb during trainingG Lorimer Moseley
Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, UK
Pain 144:314-9. 2009....
- Is reflex sympathetic dystrophy/complex regional pain syndrome type I a small-fiber neuropathy?Anne Louise Oaklander
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
Ann Neurol 65:629-38. 2009..This was labeled reflex sympathetic dystrophy (RSD; now complex regional pain syndrome type I [CRPS-I])...
- Spinal cord stimulation in patients with chronic reflex sympathetic dystrophyM A Kemler
Department of Surgery, Maastricht University Hospital, The Netherlands
N Engl J Med 343:618-24. 2000Chronic reflex sympathetic dystrophy (also called the complex regional pain syndrome) is a painful, disabling disorder for which there is no proven treatment...
- Mast cells are involved in inflammatory reactions during Complex Regional Pain Syndrome type 1Frank J P M Huygen
Pain Treatment Center, Department of Anaesthesiology, PO Box 2040, 3000 CA Rotterdam, The Netherlands
Immunol Lett 91:147-54. 2004..Involvement of mast cells is relatively easy to detect by measurement of tryptase...
- Inflammatory mediators are altered in the acute phase of posttraumatic complex regional pain syndromeChristian Schinkel
Department of Surgery, Ruhr University, Bochum, Germany
Clin J Pain 22:235-9. 2006..The pathogenesis of this syndrome is unclear. It has clinical signs of severe local inflammation as a result of an exaggerated inflammatory response, but neurogenic dysregulation also may contribute to it...
- A hypothesis for the cause of complex regional pain syndrome-type I (reflex sympathetic dystrophy): pain due to deep-tissue microvascular pathologyTerence J Coderre
Department of Anesthesia, Alan Edwards Centre for Research on Pain, McGill University, Montreal, Quebec, Canada
Pain Med 11:1224-38. 2010Complex regional pain syndrome-type I (CRPS-I; reflex sympathetic dystrophy) is a chronic pain condition that usually follows a deep-tissue injury such as fracture or sprain. The cause of the pain is unknown...
- Successful treatment of CRPS 1 with anti-TNFFrank J P M Huygen
J Pain Symptom Manage 27:101-3. 2004
- Increased skin lactate in complex regional pain syndrome: evidence for tissue hypoxia?F Birklein
Neurologische Klinik, Friedrich Alexander Universität Erlangen, Germany
Neurology 55:1213-5. 2000..95 mmol/L; control subjects 1.74 mmol/L; p < 0.005). These results suggest enhanced anaerobic glycolysis, probably as a result of chronic tissue hypoxia...
- Biphosphonates for the therapy of complex regional pain syndrome I--systematic reviewFlorian Brunner
Department of Physical Medicine and Rheumatology, Balgrist University Hospital, Forchstrasse 340, 8008 Zurich, Switzerland
Eur J Pain 13:17-21. 2009..We performed a systematic review of all randomised controlled trials to assess the benefit of biphosphonates in the treatment of CRPS I patients with bone loss...
- Evidence based guidelines for complex regional pain syndrome type 1Roberto S Perez
VU University Medical Center, Department of Anaesthesiology, Amsterdam, The Netherlands
BMC Neurol 10:20. 2010..Treatment of complex regional pain syndrome type I (CRPS-I) is subject to discussion. The purpose of this study was to develop multidisciplinary guidelines for treatment of CRPS-I...
- Concordance of qualitative bone scintigraphy results with presence of clinical complex regional pain syndrome 1: meta-analysis of test accuracy studiesR Ringer
Department of Physical Medicine and Rheumatology, Balgrist University Hospital, Zurich, Switzerland
Eur J Pain 16:1347-56. 2012..To date, no attempt has been made to investigate the agreement between qualitative bone scintigraphy (BS) and the presence of complex regional pain syndrome 1 (CRPS 1) and the agreement between a negative BS in the absence of CRPS 1...
- Predictive value of symptom level measurements for complex regional pain syndrome type IR S G M Perez
Department of Anesthesiology, VU University Medical Center, P O Box 7057, 1007 MB, Amsterdam, The Netherlands
Eur J Pain 9:49-56. 2005..We conclude that the measured pain, temperature, volume and range of motion can be used as diagnostic indicators for establishing presence or absence of CRPS I...
- Truths, errors, and lies around "reflex sympathetic dystrophy" and "complex regional pain syndrome"J L Ochoa
Department of Neurology, Good Samaritan Hospital and Oregon Health Sciences University, 1040 NW 22nd Ave N 460, Portland, OR 97210, USA
J Neurol 246:875-9. 1999The shifting paradigm of reflex sympathetic dystrophy-sympathetically maintained pains-complex regional pain syndrome is characterized by vestigial truths and understandable errors, but also unjustifiable lies...
- Meta-analysis of imaging techniques for the diagnosis of complex regional pain syndrome type IZachary J Cappello
School of Medicine and Division of Plastic Surgery, University of Louisville, Louisville, KY, USA
J Hand Surg Am 37:288-96. 2012..To compare the effectiveness of imaging techniques in aiding and confirming the diagnosis of complex regional pain syndrome (CRPS) type I...
- Demographic and medical parameters in the development of complex regional pain syndrome type 1 (CRPS1): prospective study on 596 patients with a fractureAnnemerle Beerthuizen
Department of Medical Psychology and Psychotherapy, Erasmus MC, Rotterdam, The Netherlands
Pain 153:1187-92. 2012..After a fracture, 7% of the patients developed CRPS1 and none of the patients were free of symptoms at 1-year follow-up...
- Diagnostic criteria for CRPS I: differences between patient profiles using three different diagnostic setsRoberto S G M Perez
Department of Anesthesiology, VU University Medical Center, Amsterdam, The Netherlands
Eur J Pain 11:895-902. 2007....
- [Current concepts in pathophysiology of CRPS I]F T Nickel
Universitat Erlangen, Neurologische Klinik, Erlangen
Handchir Mikrochir Plast Chir 42:8-14. 2010..These pathophysiological ideas do not exclude each other. In fact they complement one another. The variety of the involved systems may explain the versatile clinical picture of CRPS...
- Treatment of reflex sympathetic dystrophy of the hand with an active "stress loading" programH K Watson
Connecticut Combined Hand Service, Hartford Hospital, Conn
J Hand Surg Am 12:779-85. 1987b>Reflex sympathetic dystrophy (RSD) is a syndrome characterized by pain out of proportion to injury, vasomotor and trophic changes, stiffness, and decreased function...
- Complex regional pain syndrome (reflex sympathetic dystrophy) in a patient with essential mixed cryoglobulinemia and chronic hepatitis CAnkur Bant
Department of Internal Medicine, Maricopa Integrated Health System, Phoenix, AZ 85008, USA
J Pak Med Assoc 57:96-8. 2007..Complex Regional Pain Syndrome type I (CRPS) or Reflex sympathetic dystrophy (RSD) has never been reported in association with HCV...
- Pain exposure physical therapy may be a safe and effective treatment for longstanding complex regional pain syndrome type 1: a case seriesJan Willem Ek
Department of Rehabilitation Medicine, Bethesda Hospital, Hoogeveen
Clin Rehabil 23:1059-66. 2009..To determine if treatment of longstanding complex regional pain syndrome type 1, focusing on functional improvement only while neglecting pain, results in clinical improvement of this syndrome...
- Safety of "pain exposure" physical therapy in patients with complex regional pain syndrome type 1Hendrik van de Meent
Department of Rehabilitation, Nijmegen Centre of Evidence Based Practice, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
Pain 152:1431-8. 2011..A progressive-loading exercise program and management of pain-avoidance behavior without the use of specific medication ("pain exposure" physical therapy) is safe and effective for patients with complex regional pain syndrome...
- Evidence for immune system involvement in reflex sympathetic dystrophyJ S Calder
Blond McIndoe Research Centre, Queen Victoria Hospital, East Grinstead, UK
J Hand Surg Br 23:147-50. 1998Skin biopsies from patients with reflex sympathetic dystrophy were immunostained using a variety of antisera. An incidental finding with S100 staining was the presence of numerous Langerhans cells in the epidermis...
- Graded motor imagery is effective for long-standing complex regional pain syndrome: a randomised controlled trialG L Moseley
Department of Physiotherapy, The University of Queensland and Royal Brisbane and Women s Hospital, Herston, 4029 Brisbane, QLD, Australia
Pain 108:192-8. 2004..Although the mechanisms of effect of the MIP are not clear, possible explanations are sequential activation of cortical pre-motor and motor networks, or sustained and focussed attention on the affected limb, or both...
- Graded motor imagery for pathologic pain: a randomized controlled trialG Lorimer Moseley
Department of Physiology, Anatomy and Genetics and fMRIB Centre, University of Oxford, South Parks Road, Oxford OX1 3QX, UK
Neurology 67:2129-34. 2006..Graded motor imagery is effective for a small subset of patients with CRPS1...
- Clinical aspects of multifocal or generalized tonic dystonia in reflex sympathetic dystrophyJ J van Hilten
Department of Neurology, Leiden University Medical Center, The Netherlands
Neurology 56:1762-5. 2001The authors describe 10 patients with reflex sympathetic dystrophy that progressed to a multifocal or generalized tonic dystonia...
- Evidence of focal small-fiber axonal degeneration in complex regional pain syndrome-I (reflex sympathetic dystrophy)Anne Louise Oaklander
Nerve Injury Unit, Departments of Anesthesiology, Neurology, and Neuropathology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Pain 120:235-43. 2006..These results support the hypothesis that CRPS-I is specifically associated with post-traumatic focal MDNI affecting nociceptive small-fibers. This type of nerve injury will remain undetected in most clinical settings...
- Factitious disorders encountered in patients with the diagnosis of reflex sympathetic dystrophyMehmet Ali Taskaynatan
Department of Physical Medicine and Rehabilitation, Gulhane Military Medical Academy, 06018, Etlik Ankara, Turkey
Clin Rheumatol 24:521-6. 2005b>Reflex sympathetic dystrophy (RSD) may be a misdiagnosis or at least not descriptive enough in patients with atypical hand posture and atypical edema...
- Pain and reduced mobility in complex regional pain syndrome I: outcome of a prospective randomised controlled clinical trial of adjuvant physical therapy versus occupational therapyH M Oerlemans
Allied Health Services, University Hospital Nijmegen, P O Box 9101, 6500 HB, Nijmegen, Netherlands
Pain 83:77-83. 1999..Our results indicated that PT, and to a lesser extent OT, were helpful for reducing pain and improving active mobility in patients with CRPS I of less than one year duration, localised in one upper extremity...
- Treatment of complex regional pain syndrome type ITymour Forouzanfar
Pain Management and Research Centre, Department of Anesthesiology, University Hospital Maastricht, The Netherlands
Eur J Pain 6:105-22. 2002b>Reflex sympathetic dystrophy (RSD), also known as complex regional pain syndrome type I (CRPS I), is a disabling neuropathic pain syndrome...
- Correlation between a novel upper limb activity monitor and four other instruments to determine functioning in upper limb complex regional pain syndrome type IFabienne C Schasfoort
Department of Rehabilitation Medicine, Erasmus MC, Rotterdam, The Netherlands
J Rehabil Med 37:108-14. 2005....
- Neurophysiologic aspects of patients with generalized or multifocal tonic dystonia of reflex sympathetic dystrophyWillem Johan T van de Beek
Department of Neurology, Leiden University Medical Center, 2300 RC Leiden, The Netherlands
J Clin Neurophysiol 19:77-83. 2002b>Reflex sympathetic dystrophy (RSD) is a syndrome dominated by sensory, autonomic, and motor features of the extremities...
- Complex regional pain syndrome I (reflex sympathetic dystrophy)Srinivasa N Raja
Division of Pain Medicine, Department of Anesthesiology and Critical Care Medicine, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
Anesthesiology 96:1254-60. 2002
- Chronic post-ischemia pain (CPIP): a novel animal model of complex regional pain syndrome-type I (CRPS-I; reflex sympathetic dystrophy) produced by prolonged hindpaw ischemia and reperfusion in the ratTerence J Coderre
Department of Anesthesia, Anesthesia Research Unit, McGill University, Room 1203, McIntyre Bldg, 3655 Drummond St, Montreal, Que, Canada H3G 1Y6
Pain 112:94-105. 2004..ischemia and reperfusion, creating an animal model of complex regional pain syndrome-Type I (CRPS-I; reflex sympathetic dystrophy) that we call chronic post-ischemia pain (CPIP)...
- Reflex sympathetic dystrophy: a multidisciplinary approachSusan M Maillard
Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
Arthritis Rheum 51:284-90. 2004
- Economic evaluation of spinal cord stimulation for chronic reflex sympathetic dystrophyMarius A Kemler
Department of Surgery, Maastricht University Hospital, Maastricht, The Netherlands
Neurology 59:1203-9. 2002To evaluate the economic aspects of treatment of chronic reflex sympathetic dystrophy (RSD) with spinal cord stimulation (SCS), using outcomes and costs of care before and after the start of treatment.
- The effect of spinal cord stimulation in patients with chronic reflex sympathetic dystrophy: two years' follow-up of the randomized controlled trialMarius A Kemler
Department of Plastic Surgery, Medical Center Leeuwarden, Leeuwarden
Ann Neurol 55:13-8. 2004Chronic reflex sympathetic dystrophy is a painful, disabling disorder for which no treatment with proven effect is available...
- Evidence for local inflammation in complex regional pain syndrome type 1Frank J P M Huygen
Department of Anesthesiology, Erasmus Medical Centre, Rotterdam, The Netherlands
Mediators Inflamm 11:47-51. 2002..Peripheral afferent, efferent and central mechanisms are supposed. Based on clinical signs and symptoms (e.g. oedema, local temperature changes and chronic pain) local inflammation is suspected...
- The treatment of complex regional pain syndrome type I with free radical scavengers: a randomized controlled studyR S G M Perez
Department of Anesthesiology, Vrije Universiteit Medical Center, P O Box 7057, 1007 MB Amsterdam, The Netherlands
Pain 102:297-307. 2003..Strong indications exist for differences in effects for subgroups of patients with warm or cold CRPS I: for warm CRPS I, DMSO-treatment appears more favorable, while for cold CRPS I, NAC-treatment appears to be more effective...
- Impairments as measured by ISS do not greatly change between one and eight years after CRPS 1 diagnosisMichiel Vaneker
Pain Centre, Department of Anaesthesiology, Radboud University Medical Centre Nijmegen, P O Box 9101, 6500 HB Nijmegen, The Netherlands
Eur J Pain 10:639-44. 2006..e. "warm" or "cold", diagnosed according to skin temperature measured via infrared thermometer)...
- The usefulness of quantitative evaluation of three-phase scintigraphy in the diagnosis of post-traumatic reflex sympathetic dystrophyA Zyluk
Department of General and Hand Surgery, Pomeranian Medical University, Szczecin, Poland
J Hand Surg Br 24:16-21. 1999Quantitative analysis of three-phase bone scintigrams was done in 70 patients with reflex sympathetic dystrophy (RSD) and in 30 patients who did not have RSD after injury to the hand or wrist...
- Evaluation of three methods to rate impairment in patients with complex regional pain syndrome I of one upper extremityH M Oerlemans
Allied Health Services, University Medical Center Nijmegen, The Netherlands
Clin Rehabil 14:331-9. 2000..To gain insight into the best way of obtaining an impairment rating in complex regional pain syndrome I (CRPS I) of the upper extremity. This syndrome can potentially result in permanent impairment...
- Increased endothelin-1 and diminished nitric oxide levels in blister fluids of patients with intermediate cold type complex regional pain syndrome type 1J George Groeneweg
Department of Anesthesiology, subdivision Pain Treatment Center, Erasmus MC Rotterdam, The Netherlands
BMC Musculoskelet Disord 7:91. 2006..The aim of this study was to determine the involvement of vasoactive substances endothelin-1 (ET-1) and nitric oxide (NO) during early chronic CRPS1...
- Vascular abnormalities in reflex sympathetic dystrophy (CRPS I): mechanisms and diagnostic valueG Wasner
, , Kiel, Niemannsweg 147, 24105 Kiel, Germany
Brain 124:587-99. 2001Complex regional pain syndrome type I (CRPS I, formerly known as reflex sympathetic dystrophy) is a painful neuropathic disorder that develops after trauma affecting the limbs without overt nerve injury...
- Spinal cord stimulation for chronic reflex sympathetic dystrophy--five-year follow-upMarius A Kemler
N Engl J Med 354:2394-6. 2006
- Proprioceptive reflexes in patients with reflex sympathetic dystrophyA C Schouten
Delft University of Technology, Department of Mechanical Engineering, Man Machine Systems and Control, Mekelweg 2, 2628 CD Delft, Leiden, The Netherlands
Exp Brain Res 151:1-8. 2003b>Reflex sympathetic dystrophy (RSD) is a syndrome that frequently follows an injury and is characterized by sensory, autonomic and motor features of the affected extremities...
- Diagnosing sensory abnormalities with either normal values or values from contralateral skin: comparison of two approaches in complex regional pain syndrome IM A Kemler
Department of Surgery, Maastricht University Hospital, Maastricht, The Netherlands
Anesthesiology 93:718-27. 2000..The current study gives normal values for both approaches and compares the advantages of each method by applying the technique to patients with complex regional pain syndrome type I (CRPS I)...
- Signs and symptoms in complex regional pain syndrome type I/reflex sympathetic dystrophy: judgment of the physician versus objective measurementH M Oerlemans
Allied Health Services, University Hospital Nijmegen, The Netherlands
Clin J Pain 15:224-32. 1999..To assess the relation between the subjectively assessed and objectively measured diagnostic signs and symptoms in complex regional pain syndrome type I (CRPS I) and to quantify their severity...
- Reflex sympathetic dystrophy: complex regional pain syndrome type I in children with mitochondrial disease and maternal inheritanceT Higashimoto
Division of Medical Genetics and the Saban Research Institute, Childrens Hospital Los Angeles, Los Angeles, California, USA
Arch Dis Child 93:390-7. 2008Complex regional pain syndrome type I (CRPS-I), previously known as reflex sympathetic dystrophy (RSD), is an idiopathic condition characterised by localised, abnormally intense and prolonged pain, allodynia and autonomic nervous system ..
- Reflex sympathetic dystrophy following arterial blood gas sampling in the intensive care settingC Criscuolo
Department of Medicine, University of Nebraska Medical Center, Omaha, USA
Chest 108:578-80. 1995A 54-year-old woman developed signs and symptoms consistent with reflex sympathetic dystrophy in her left upper extremity following arterial puncture...
- Intravenous clodronate in the treatment of reflex sympathetic dystrophy syndrome. A randomized, double blind, placebo controlled studyM Varenna
Department of Rheumatology, Istituto Ortopedico Gaetano Pini, Milano, Italy
J Rheumatol 27:1477-83. 2000To evaluate the efficacy of intravenous (i.v.) clodronate in patients with reflex sympathetic dystrophy syndrome (RSDS) and to assess the urinary excretion of type I collagen crosslinked N-telopeptide (NTx) before and after the treatment.
- Endothelial dysfunction in cold type complex regional pain syndromeJ Schattschneider
Division of Neurological Pain Research and Therapy, Department of Neurology, University Hospital of Schleswig Holstein, Campus Kiel, Kiel, Germany
Neurology 67:673-5. 2006..No significant differences were found after application of sodium nitroprusside. The results demonstrate impaired endothelial function in chronic CRPS I...
- Intrathecal baclofen for the treatment of dystonia in patients with reflex sympathetic dystrophyB J van Hilten
Department of Neurology, Leiden University Medical Center, The Netherlands
N Engl J Med 343:625-30. 2000Patients with reflex sympathetic dystrophy (also known as the complex regional pain syndrome) may have dystonia, which is often unresponsive to treatment...
- Skin temperature side differences--a diagnostic tool for CRPS?Gunnar Wasner
Klinik fur Neurologie, Universitätsklinikum Kiel der Christian Albrechts Universität, Niemannsweg 147, 24105 Kiel, Germany
Pain 98:19-26. 2002..Taking this into consideration, skin temperature differences in the distal limbs are capable of reliably distinguishing CRPS I from other extremity pain syndromes with high sensitivity and specificity...
- The effect of gabapentin in earlier stage of reflex sympathetic dystrophyArif Kenan Tan
Department of Physical Medicine and Rehabilitation, Gulhane Military Medical Academy, 06018 Etlik, Ankara, Turkey
Clin Rheumatol 26:561-5. 2007The objective of this paper is to investigate the effect of gabapentin in the earlier stage of reflex sympathetic dystrophy syndrome (RSD). Twenty-two patients diagnosed with RSD were enrolled. Initial gabapentin dosage was 600 mg/day...
- A critical review of controlled clinical trials for peripheral neuropathic pain and complex regional pain syndromesW S Kingery
Physical Medicine and Rehabilitation Service, Veterans Affairs Palo Alto Health Care System, CA 94304, USA
Pain 73:123-39. 1997..There was almost no overlap in the controlled trial literature between treatments for PNP and CRPS, and treatments used in both conditions (intravenous phentolamine and epidural clonidine) had similar results...
- Incidence of complex regional pain syndrome type I after fractures of the distal radiusPieter U Dijkstra
Department of Rehabilitation, University Hospital Groningen, PO Box 30 001, 9700 RB, Groningen, The Netherlands
Eur J Pain 7:457-62. 2003..2 to 6%) after fractures of the distal radius. Further the risk factors described in literature play a minor role in the development of CRPS-I...
- Reflex sympathetic dystrophy: a retrospective epidemiological study of 168 patientsIltekin Duman
Department of Physical Medicine and Rehabilitation, Gulhane Military Medical Academy, 06018, Etlik, Ankara, Turkey
Clin Rheumatol 26:1433-7. 2007..factors, duration of symptoms, treatment modalities applied and clinical outcome of the treatment in reflex sympathetic dystrophy (RSD)...
- Reflex sympathetic dystrophy: treatment with long-acting intramuscular corticosteroidsA B Grundberg
Division of Hand Surgery, Des Moines Orthopaedic Surgeons, West Des Moines, IA, USA
J Hand Surg Am 21:667-70. 1996In an 8-year period, 69 patients with reflex sympathetic dystrophy, who were followed at least 1 year, were treated with active exercises and injections of long-acting methylprednisolone...
- Randomised controlled trial of gabapentin in Complex Regional Pain Syndrome type 1 [ISRCTN84121379]Anton C van de Vusse
Pain Management and Research Centre, Dept of Anesthesiology, University Hospital Maastricht, Maastricht, The Netherlands
BMC Neurol 4:13. 2004Complex Regional Pain Syndrome type one (CRPS I) or formerly Reflex Sympathetic Dystrophy (RSD) is a disabling syndrome, in which a painful limb is accompanied by varying symptoms...
- Sympathetic skin responses in reflex sympathetic dystrophyK Bolel
Department of Physical Medicine and Rehabilitation, Cumhuriyet University School of Medicine, 58140 Sivas, Turkey
Rheumatol Int 26:788-91. 2006..SSR) in evaluating the sympathetic function and to follow up the effects of sympathetic blockade in reflex sympathetic dystrophy (RSD)...
- Determination of inflammation of reflex sympathetic dystrophy at early stages with Tc-99m HIG scintigraphy: preliminary resultsBerna Okudan
Department of Nuclear Medicine, Ankara Numune Research and Training Hospital, Ankara, Turkey
Rheumatol Int 26:404-8. 2006The pathogenesis of reflex sympathetic dystrophy (RSD) is not completely understood...
- Efficacy of salmon calcitonin in complex regional pain syndrome (type 1) in addition to physical therapyFusun Sahin
Department of Physical Medicine and Rehabilitation, Sisli Etfal Education and Research Hospital, Istanbul, Turkey
Clin Rheumatol 25:143-8. 2006..We can conclude that calcitonin does not make any favourable contribution in the treatment of patients with acute CRPS 1; physical therapy combined with only a simple analgesic is an efficient means of therapy...
- Spinal cord stimulation in sympathetically maintained complex regional pain syndrome type I with severe disability. A prospective clinical studyHenning Harke
Department of Anesthesia and Pain Therapy, Klinikum Krefeld, Lutherplatz 40, D 47805 Krefeld, Germany
Eur J Pain 9:363-73. 2005..In this prospective trial we assessed the long-term effect of spinal cord stimulation (SCS) on the improvement of functional status in complex regional pain syndrome type I (CRPS I)...
- Efficacy of stellate ganglion blockade for the management of type 1 complex regional pain syndromeWilliam E Ackerman
Pain Medicine Consultants PA, Little Rock, AR, USA
South Med J 99:1084-8. 2006..The purpose of this study was to examine the efficacy of stellate ganglion blockade (SGB) in patients with complex regional pain syndromes (CRPS I) of their hands...
- Sensorimotor retuning [corrected] in complex regional pain syndrome parallels pain reductionBurkhard Pleger
Department of Neurology, BG Kliniken Bergmannsheil, Ruhr University Bochum, Buerkle de la Camp Platz 1, DD 47789 Bochum, Germany
Ann Neurol 57:425-9. 2005..This suggests that the reversal of tactile impairment and cortical reorganization in CRPS is associated with a decrease in pain...
- Pathologic alterations of cutaneous innervation and vasculature in affected limbs from patients with complex regional pain syndromePhillip J Albrecht
Center for Neuropharmacology and Neuroscience, Albany Medical College, Albany, NY, USA
Pain 120:244-66. 2006..CRPS type I, also known as reflex sympathetic dystrophy, presents in patients lacking a well-defined nerve lesion, and has been questioned as to whether or not ..
- Continuous peripheral nerve blocks at home for treatment of recurrent complex regional pain syndrome I in childrenChristophe Dadure
Department of Anesthesia and Critical Care Medicine, Lapeyronie University Hospital, Montpellier, France
Anesthesiology 102:387-91. 2005....
- Exaggeration of tissue trauma induces signs and symptoms of acute CRPS I, however displays distinct differences to experimental CRPS IIGeorg Gradl
Department of Trauma and Reconstructive Surgery, University of Rostock, Germany
Neurosci Lett 402:267-72. 2006..Pain perception displays differences to that in CRPS II. Apoptosis turns out to be a distinctive marker for CRPS, warranting further evaluation in clinical studies...
- Intravenous regional anesthesia with ketorolac-lidocaine for the management of sympathetically-mediated painN R Connelly
Department of Anesthesiology, Tufts University School of Medicine, Baystate Medical Center, Springfield, Massachusetts, USA
Yale J Biol Med 68:95-9. 1995..Sixty-one patients with reflex sympathetic dystrophy presenting to a university-affiliated teaching hospital's pain management center were evaluated...
- Role of alendronate in therapy for posttraumatic complex regional pain syndrome type I of the lower extremityDaniel Henri Manicourt
St Luc University Hospital, Universite Catholique de Louvain, 5390 Avenue Mounier, 1200 Brussels, Belgium
Arthritis Rheum 50:3690-7. 2004..To evaluate the effects of the antiresorptive agent alendronate at a daily oral dose of 40 mg in patients with posttraumatic complex regional pain syndrome type I (CRPS I) of the lower extremity...
- Magnetic resonance imaging in reflex sympathetic dystrophy syndrome of the footFrançoise Crozier
Department of Radiology, CHU Timone, 254, rue St Pierre, 13385 Marseille Cedex 5, France
Joint Bone Spine 70:503-8. 2003The purpose was to analyze magnetic resonance imaging (MRI) abnormalities in reflex sympathetic dystrophy syndrome (RSDS) of the foot, with the goal of helping to meet the difficult diagnostic challenges raised by this condition.
- Intravenous regional anesthesia with clonidine in the management of complex regional pain syndrome of the kneeScott S Reuben
Department of Anesthesiology, Baystate Medical Center, Springfield, MA 01199, USA
J Clin Anesth 14:87-91. 2002..To evaluate the safety and efficacy of administering intravenous regional anesthesia (IVRA) with clonidine in the management of complex regional pain syndrome (CRPS) of the knee...
- Ketamine produces effective and long-term pain relief in patients with Complex Regional Pain Syndrome Type 1Marnix J Sigtermans
Department of Anesthesiology, Leiden University Medical Center, P O Box 9600, 2300 RC Leiden, The Netherlands
Pain 145:304-11. 2009..Treatment with ketamine was safe with psychomimetic side effects that were acceptable to most patients...
- Measuring perceived activity limitations in lower extremity Complex Regional Pain Syndrome type 1 (CRPS I): test-retest reliability of two questionnairesRoberto S G M Perez
Department of Anesthesiology, University Hospital Vrije Universiteit, Amsterdam, The Netherlands
Clin Rehabil 16:454-60. 2002..To assess the test-retest reliability of two questionnaires for measuring activity limitations in patients with Complex Regional Pain Syndrome type 1 (CRPS I) of the lower extremity...
- Management of lower limb complex regional pain syndrome type 1: an evaluation of percutaneous radiofrequency thermal lumbar sympathectomy versus phenol lumbar sympathetic neurolysis--a pilot studyPrashanth S Manjunath
Department of Anesthesiology, University of Miami Jackson Memorial Hospital, Miami, FL, USA
Anesth Analg 106:647-9, table of contents. 2008..The purpose of this study was to compare the safety and efficacy of two therapeutic options: percutaneous radiofrequency thermal lumbar sympathectomy and lumbar sympathetic neurolysis...
- Intravenous regional guanethidine blockade in the treatment of post-traumatic complex regional pain syndrome type 1 (algodystrophy) of the handJ A Livingstone
University Department of Orthopaedic Surgery, Bristol Royal Infirmary, England, UK
J Bone Joint Surg Br 84:380-6. 2002..It does not improve the outcome of this condition and may delay the resolution of vasomotor instability when compared with the placebo...
- Is fibromyalgia a generalized reflex sympathetic dystrophy?M Martinez-Lavin
Rheumatology Department, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano No 1, 14080 México D F Mexico
Clin Exp Rheumatol 19:1-3. 2001Fibromyalgia and reflex sympathetic dystrophy share defining characteristics, namely chronic pain and allodynia, as well as other important clinical features such as onset after trauma, female predominance, paresthesias, vasomotor ..
- Reflex sympathetic dystrophyRobert J Schwartzman
Department of Neurology, MCP Hahnemann University School of Medicine, Broad and Vine Streets, MS 423, Philadelphia, PA 19102 1192, USA
Curr Rheumatol Rep 4:165-9. 2002b>Reflex sympathetic dystrophy (RSD) is composed of five major features: pain, swelling, autonomic dysregulation, movement disorders, and atrophy and dystrophy...
- Surgical sympathectomy for reflex sympathetic dystrophy syndromesDennis F Bandyk
Department of Vascular Surgery, University of South Florida College of Medicine, Tampa, USA
J Vasc Surg 35:269-77. 2002The purpose of this study was the assessment of the efficacy of thoracoscopic cervicodorsal and open lumbar sympathectomy for the reduction of pain severity and disability associated with reflex sympathetic dystrophy (RSD).
- Treatment of patients with complex regional pain syndrome type I with mannitol: a prospective, randomized, placebo-controlled, double-blinded studyRoberto S Perez
VU University Medical Center, Department of Anesthesiology, Amsterdam, The Netherlands
J Pain 9:678-86. 2008..Whether 10% mannitol can provide beneficial effects for subgroups of CRPS I patients with a pathophysiological profile more closely fitting the presumed mode of action for this intervention remains to be established...
- Which patients with chronic reflex sympathetic dystrophy are most likely to benefit from physical therapy?M A Kemler
Department of Surgery, Maastricht University Hospital, Maastricht, The Netherlands
J Manipulative Physiol Ther 24:272-8. 2001Chronic reflex sympathetic dystrophy (RSD) is a painful and disabling disorder for which no treatment with proven effects exists...
- Preventing recurrence of reflex sympathetic dystrophy in patients requiring an operative intervention at the site of dystrophy after surgeryC Marx
Department of Rheumatology and Institute for Physical Medicine, University Hospital Zurich, Switzerland
Clin Rheumatol 20:114-8. 2001The development of reflex sympathetic dystrophy (RSD) is a common complication after surgery. Exacerbation or recurrence of RSD is a major concern after a second intervention at the site of previous surgery and consecutive RSD...
- Clinical and physiologic evaluation of stellate ganglion blockade for complex regional pain syndrome type IM Schurmann
Department of Surgery, Ludwig Maximilians University, Munich, Germany
Clin J Pain 17:94-100. 2001..Results were compared with clinical signs such as temperature changes, pain reduction, and the development of Horner syndrome to evaluate the correlation with clinical investigations...
- An open-label pilot trial of ibandronate for complex regional pain syndromeBrenda Breuer
Department of Pain Medicine and Palliative Care, Beth Israel Medical Center, New York, NY 10003, USA
Clin J Pain 24:685-9. 2008Complex regional pain syndrome (CRPS) type I, also known as reflex sympathetic dystrophy, usually develops after trauma or immobilization, is characterized by focal pain and autonomic dysregulation, and sometimes focal trophic changes ..
- The efficacy of manual lymphatic drainage therapy in the management of limb edema secondary to reflex sympathetic dystrophyIltekin Duman
Department of Physical Medicine and Rehabilitation, Gulhane Military Medical Academy, Etlik, 06018, Ankara, Turkey
Rheumatol Int 29:759-63. 2009..is to investigate the efficacy of manual lymphatic drainage (MLD) therapy in edema secondary to the reflex sympathetic dystrophy (RSD). A total of 34 patients were allocated randomly into two groups...
- Intravenous magnesium for complex regional pain syndrome type 1 (CRPS 1) patients: a pilot studySusan Collins
Department of Anesthesiology, VU University Medical Center, Amsterdam, The Netherlands
Pain Med 10:930-40. 2009..To explore the feasibility of intravenous magnesium administration as a potential candidate intervention for a large size trial in Complex Regional Pain Syndrome Type 1 (CRPS 1)...
- Short- and long-term outcomes of children with complex regional pain syndrome type I treated with exercise therapyD D Sherry
Department of Pediatrics, University of Washington, Children s Hospital and Medical Center, Seattle 98105, USA
Clin J Pain 15:218-23. 1999..To report the initial and long-term outcome after an intensive exercise therapy program for childhood complex regional pain syndrome, type I (CRPS)...
- The Radboud skills questionnaire: construction and reliability in patients with reflex sympathetic dystrophy of one upper extremityH M Oerlemans
Allied Health Services, University Hospital Nijmegen, The Netherlands
Disabil Rehabil 22:233-45. 2000..To construct a questionnaire to measure skills in which notably both hands are active, which is suitable for patients with a disease of one or both hands and to research its response stability and possible improvements...
- Complex regional pain syndrome type I induced by pacemaker implantation, with a good response to steroids and neurotropinMakoto Okada
Internal Medicine I, National Defense Medical College, Tokorozawa, Saitama
Intern Med 41:498-501. 2002..She was diagnosed to have CRPS-I, which was considered to have been induced by the pacemaker implantation. After treatment with methylprednisolone and Neurotropin, her symptoms dramatically improved...
- Spinal cord stimulation in adolescents with complex regional pain syndrome type I (CRPS-I)Gunnar L Olsson
Pain Treatment Unit, Astrid Lindgren Children s Hospital, 17176, Stockholm, Sweden
Eur J Pain 12:53-9. 2008....
- Can vitamin C prevent complex regional pain syndrome in patients with wrist fractures? A randomized, controlled, multicenter dose-response studyP E Zollinger
Department of Surgery, Red Cross Hospital, Beverwijk, The Netherlands
J Bone Joint Surg Am 89:1424-31. 2007..Complex regional pain syndrome type I is treated symptomatically. A protective effect of vitamin C (ascorbic acid) has been reported previously. A dose-response study was designed to evaluate its effect in patients with wrist fractures...
- Vasodilative effect of isosorbide dinitrate ointment in complex regional pain syndrome type 1George Groeneweg
Department of Anesthesiology, Subdivision Pain Treatment Centre, Erasmus MC, Rotterdam, The Netherlands
Clin J Pain 24:89-92. 2008..Pharmacotherapeutic treatment is generally inadequate...
- [Vitamin C and prevention of reflex sympathetic dystrophy following surgical management of distal radius fractures]J F Cazeneuve
Service de Chirurgie Orthopedique et Traumatologique, Centre Hospitalier, Rue Marcellin Berthelot, 02 000 Laon, France
Acta Orthop Belg 68:481-4. 2002b>Reflex sympathetic dystrophy is a major complication following surgical treatment of fractures of the distal radius...
- Sympathetic nervous system and pain: a clinical reappraisalH Blumberg
Department of Neurosurgery, University of Freiburg, Germany
Behav Brain Sci 20:426-34; discussion 435-513. 1997..To this end, the patients under study are divided into three groups. In the first group, called "reflex sympathetic dystrophy" (RSD), the syndrome can be characterized by a triad of autonomic, motor, and sensory symptoms, which ..
- [A hairy condition]Renate Wiesner
MMW Fortschr Med 146:57. 2004
- Acute posttraumatic ischemia of the limbs: algodystrophy or related syndrome? A prospective study on a series of 25 patientsMarc Antoine Pistorius
Department of Internal and Vascular Medicine, University Hospital Hotel Dieu, Nantes, France
Angiology 59:301-5. 2008..The symptoms may recur, but they respond to physiotherapy. Patients' follow-up showed that microcirculatory function remains abnormal sometime after the initial episode with, in particular, an exacerbation of the venoarteriolar reflex...
- Opioid Efficacy In Humans: A Twin StudyDAVID J contact CLARK; Fiscal Year: 2010....
- Inflammasome Activation in Complex Regional Pain SyndromeWade S Kingery; Fiscal Year: 2013....
- MECHANISM OF NOCICEPTION INDUCED BY INNOCUOUS COLD IN TRIGEMINAL SYSTEMJianguo Gu; Fiscal Year: 2012Orofacial pain disorders encompass a wide range of conditions including trigeminal neuralgia, reflex sympathetic dystrophy (RSD) of the face, temporomandibular joint disorders, periodontal pain, burning mouth syndrome, dental surgical ..
- POSTMORTEM STUDIES OF PAINFUL PERIPHERAL NEUROPATHYVIRGINIA SEYBOLD; Fiscal Year: 1991..Tissue donors with pre-morbid history of reflex sympathetic dystrophy or causalgia will be the primary focus of this work because of the similarity between the symptoms and ..
- SYMPATHETIC EFFERENT MODULATION OF PAINWilliam Roberts; Fiscal Year: 1993..research program is to understand the physiology of sympathetically dependent pain, such as that in reflex sympathetic dystrophy, acute herpes zoster and some cases of low back pain...
- Neurite density in skin as a marker for neuropathic painAnne Louise Oaklander; Fiscal Year: 2005..abstract_text> ..
- Mentored Patient-Oriented Research Career Development AwPaola Sandroni; Fiscal Year: 2004..Sandroni with the necessary conceptual development, publications track record and investigational tools to effectively compete as an independent investigator in autonomic disorders in future years. ..
- The Roles of Heme Oxygenase in PainDavid Clark; Fiscal Year: 2005....
- Genetics of Opioid Induced HyperalgesiaDavid Clark; Fiscal Year: 2004..Thus our overall goal is to bring a unique and complimentary approach to the ongoing studies of OIH by using genomics to objectively identify genes involved in this phenomenon. ..
- MECHANISMS FOR TOLERANCE TO ACTIONS OF A2 AGONISTSDavid Clark; Fiscal Year: 2002..Data from these studies can be used to develop therapeutic strategies to prevent or reverse tolerance. ..
- Nasal Delivery of Naltrexone for Treatment of AlcoholismDaniel Wermeling; Fiscal Year: 2006..The long-term goal of this work is to develop and commercialize nasal delivered NTX for the treatment of alcoholism. [unreadable] [unreadable] [unreadable]..