female genital neoplasms

Summary

Summary: Tumor or cancer of the female reproductive tract (GENITALIA, FEMALE).

Top Publications

  1. ncbi [Pelvic exenterations for gynaecological cancer--a 10 year institutional review]
    Sueli Pinelo
    Serviço de Ginecologia, Instituto Portugues de Oncologia, Porto
    Acta Med Port 19:99-104. 2006
  2. ncbi Mammaglobin expression in gynecologic malignancies and malignant effusions detected by nested reverse transcriptase-polymerase chain reaction
    Kurt Grünewald
    Department of Internal Medicine, University of Innsbruck, Innsbruck, Austria
    Lab Invest 82:1147-53. 2002
  3. ncbi Positron emission tomography in gynecologic cancer
    Tzu Chen Yen
    Department of Nuclear Medicine, Molecular Imaging Center, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan
    Semin Nucl Med 36:93-104. 2006
  4. ncbi PET imaging in gynecologic malignancies
    Rakesh Kumar
    Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, 110 Donner Building, Philadelphia, PA 19104, USA
    Radiol Clin North Am 42:1155-67, ix. 2004
  5. ncbi Quality of life: gynaecological cancers
    S Pignata
    Oncologia Medica B Istituto Nazionale Tumori, Naples, Italy
    Ann Oncol 12:S37-42. 2001
  6. ncbi Detection and evaluation of pelvic lymph nodes in patients with gynecologic malignancies using body diffusion-weighted magnetic resonance imaging
    Go Nakai
    Department of Radiology, Osaka Medical College, Osaka, Japan
    J Comput Assist Tomogr 32:764-8. 2008
  7. ncbi Health-related quality of life in gynecological oncology: instruments and psychometric properties
    W Boling
    Department of Health and Human Performance, University of Houston, University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4095, USA
    Int J Gynecol Cancer 13:5-14. 2003
  8. ncbi USPIO-enhanced MRI for preoperative staging of gynecological pelvic tumors: preliminary results
    Thomas M Keller
    Institute of Diagnostic Radiology, Zurich University Hospital, Zurich, Switzerland
    Eur Radiol 14:937-44. 2004
  9. ncbi The diagnostic accuracy of 18F-fluorodeoxyglucose PET/CT in patients with gynecological malignancies
    Dan Grisaru
    Department of Obstetrics and Gynecology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Gynecol Oncol 94:680-4. 2004
  10. ncbi Pearls and pitfalls of MR lymphography in gynecologic malignancy
    Priya Narayanan
    Academic Department of Radiology, St Bartholomew s Hospital, Dominion House, 59 Bartholomew Close, London EC1A 7ED, England
    Radiographics 29:1057-69; discussion 1069-71. 2009

Research Grants

  1. HER-2 NEU PROTO-ONCOGENE IN OVARIAN & ENDOMETRIAL CANCER
    Michael Press; Fiscal Year: 1993
  2. GYNECOLOGIC ONCOLOGY GROUP
    James Thigpen; Fiscal Year: 1980
  3. CYCLIC GMP LEVELS IN GYNECOLOGIC NEOPLASMS
    Chandralekha Duttagupta; Fiscal Year: 1980
  4. Facilitating Informed Decisions for MSI Testing
    Sharon Manne; Fiscal Year: 2008
  5. Tailored Intervention for Melanoma Patients' Families
    Sharon Manne; Fiscal Year: 2008
  6. Colon Cancer Screening for Cancer Patients' Families
    Sharon Manne; Fiscal Year: 2006
  7. Improving Patient Adherence to Cancer Treatment
    Kathleen Ell; Fiscal Year: 2004
  8. Multifaceted Depression Diabetes Program for Hispanics
    Kathleen Ell; Fiscal Year: 2008
  9. Healing Touch, Immunity, and Fatigue in Breast Cancer
    Susan Lutgendorf; Fiscal Year: 2004
  10. Biobehavioral-Cytokine Interactions in Ovarian Cancer
    Susan Lutgendorf; Fiscal Year: 2007

Detail Information

Publications221 found, 100 shown here

  1. ncbi [Pelvic exenterations for gynaecological cancer--a 10 year institutional review]
    Sueli Pinelo
    Serviço de Ginecologia, Instituto Portugues de Oncologia, Porto
    Acta Med Port 19:99-104. 2006
    ..It is used for treatment of primary or recurrent tumours, or, more usually in treatment of recurrent cervical cancer...
  2. ncbi Mammaglobin expression in gynecologic malignancies and malignant effusions detected by nested reverse transcriptase-polymerase chain reaction
    Kurt Grünewald
    Department of Internal Medicine, University of Innsbruck, Innsbruck, Austria
    Lab Invest 82:1147-53. 2002
    ....
  3. ncbi Positron emission tomography in gynecologic cancer
    Tzu Chen Yen
    Department of Nuclear Medicine, Molecular Imaging Center, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Taoyuan, Taiwan
    Semin Nucl Med 36:93-104. 2006
    ..Evaluating PET by clinical benefit is specific to the individual tumor and an attractive new endpoint...
  4. ncbi PET imaging in gynecologic malignancies
    Rakesh Kumar
    Division of Nuclear Medicine, Department of Radiology, Hospital of the University of Pennsylvania, 3400 Spruce Street, 110 Donner Building, Philadelphia, PA 19104, USA
    Radiol Clin North Am 42:1155-67, ix. 2004
    ..Normal FDG activity in the gastrointestinal tract and bladder may obscure some lesions. Combined PET/CT can help in localizing lesions and differentiating between pathologic and physiologic uptake in the pelvis and abdomen...
  5. ncbi Quality of life: gynaecological cancers
    S Pignata
    Oncologia Medica B Istituto Nazionale Tumori, Naples, Italy
    Ann Oncol 12:S37-42. 2001
    ..In this report, we will discuss the aspects affecting the QoL in gynaecological cancer in relation to surgical treatment, medical therapy, and follow-up...
  6. ncbi Detection and evaluation of pelvic lymph nodes in patients with gynecologic malignancies using body diffusion-weighted magnetic resonance imaging
    Go Nakai
    Department of Radiology, Osaka Medical College, Osaka, Japan
    J Comput Assist Tomogr 32:764-8. 2008
    ..In this study, the potential in detecting and evaluating pelvic lymph node metastases on body diffusion-weighted (DW) images was evaluated in patients with gynecologic malignancies...
  7. ncbi Health-related quality of life in gynecological oncology: instruments and psychometric properties
    W Boling
    Department of Health and Human Performance, University of Houston, University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4095, USA
    Int J Gynecol Cancer 13:5-14. 2003
    ....
  8. ncbi USPIO-enhanced MRI for preoperative staging of gynecological pelvic tumors: preliminary results
    Thomas M Keller
    Institute of Diagnostic Radiology, Zurich University Hospital, Zurich, Switzerland
    Eur Radiol 14:937-44. 2004
    ..However, the low sensitivity in the present study is a limitation for the clinical application of this technique...
  9. ncbi The diagnostic accuracy of 18F-fluorodeoxyglucose PET/CT in patients with gynecological malignancies
    Dan Grisaru
    Department of Obstetrics and Gynecology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Gynecol Oncol 94:680-4. 2004
    ..To evaluate the diagnostic accuracy of integrated positron emission tomography/computerized tomography (PET/CT) in patients with gynecological cancer...
  10. ncbi Pearls and pitfalls of MR lymphography in gynecologic malignancy
    Priya Narayanan
    Academic Department of Radiology, St Bartholomew s Hospital, Dominion House, 59 Bartholomew Close, London EC1A 7ED, England
    Radiographics 29:1057-69; discussion 1069-71. 2009
    ..However, as with any technique, there are pitfalls that the radiologist must be aware of to avoid interpretative errors...
  11. ncbi Prospective assessment of quality of life of female cancer patients
    E Greimel
    Department of Obstetrics and Gynecology, Karl Franzens University Graz, Graz, 8036, Austria
    Gynecol Oncol 85:140-7. 2002
    ....
  12. ncbi Quality of life in patients attending a low-risk gynaecological oncology follow-up clinic
    R L Leake
    King Edward Memorial Hospital, Bagot Road, Subiaco, Western Australia, Australia
    Psychooncology 10:428-35. 2001
    ..Patients living with partners experienced deterioration in sexual functioning. CONCLUSIONS: Patients attending the low risk follow-up clinic after gynaecological malignancy have a good overall QOL...
  13. ncbi Quality of life and mood in women receiving extensive chemotherapy for gynecologic cancer
    S K Lutgendorf
    University of Iowa, Department of Psychology, Iowa City, Iowa 52242, USA
    Cancer 89:1402-11. 2000
    ..Quality of life (QOL) and mood were investigated among women who had received intensive chemotherapy for at least 1 year for advanced gynecologic cancers. Relationships of coping styles to QOL and mood in these patients also were examined...
  14. ncbi Quality of life after treatment for gynecologic malignancies: a pilot study in an outpatient clinic
    Brigitte E Miller
    Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Gynecol Oncol 87:178-84. 2002
    ..The objective of this study was to determine the health-related quality of life (QOL) of disease-free patients after therapy for gynecologic malignancies at follow-up in an outpatient clinic...
  15. ncbi Sentinel lymph node mapping in gynecologic malignancies
    P V Loar
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Michigan, Ann Arbor, MI 48109 0276, USA
    Int J Gynaecol Obstet 99:69-74. 2007
    ..Sentinel node mapping is currently being investigated for treatment of gynecologic cancers. Recent studies show promise for incorporating the sentinel node mapping technique for treatment of several gynecologic malignancies...
  16. ncbi Comparison of different nutritional assessments and body-composition measurements in detecting malnutrition among gynecologic cancer patients
    Brenda Laky
    Queensland Centre for Gynaecological Cancer, The Royal Brisbane and Women s Hospital, Brisbane, Australia
    Am J Clin Nutr 87:1678-85. 2008
    ..Few studies have assessed global nutritional assessment tools and body-composition measurements in gynecologic cancer patients...
  17. ncbi Evaluation of quality of life in Chinese patients with gynaecological cancer: assessments by patients and nurses
    Hong Zhao
    School of Nursing, Peking Union Medical College, Beijing, China
    Int J Nurs Pract 9:40-8. 2003
    ..The nurses need to be trained to become more sensitive and competent in assessing patients' subjective information...
  18. ncbi Complementary and alternative medicine use in patients with gynecological cancers in Europe
    A Molassiotis
    School of Nursing, University of Manchester, United Kingdom
    Int J Gynecol Cancer 16:219-24. 2006
    ..It is important to discuss CAM use with gynecological cancer patients, as they frequently use it and such use may have implications for clinical practice...
  19. ncbi Malnutrition among gynaecological cancer patients
    B Laky
    Queensland Centre for Gynaecological Cancer, The Royal Brisbane and Women s Hospital, Brisbane, Australia
    Eur J Clin Nutr 61:642-6. 2007
    ..To assess the nutritional status of patients with gynaecological cancer...
  20. ncbi Quality of life and mood in women with gynecologic cancer: a one year prospective study
    Susan K Lutgendorf
    Department of Psychology, University of Iowa, Iowa City, IA 52242, USA
    Cancer 94:131-40. 2002
    ..Quality of life (QOL) and mood were prospectively investigated during the first year of treatment among women with gynecologic cancers. Relationships of coping styles to QOL and mood were examined...
  21. ncbi Prognostic and therapeutic importance of lymphadenectomy in gynecological cancers
    A Ayhan
    Department of Obstetrics and Gynaecology, Division of Gynaecological Oncology, Hacettepe University Faculty of Medicine, Ankara, Turkey
    Eur J Gynaecol Oncol 25:279-86. 2004
    ..This study discusses the prognostic and therapeutic importance of lymphadenectomy in ovarian, endometrial, cervical and vulvar cancers...
  22. ncbi Quality of life considerations in gynecologic cancer. FIGO 26th Annual Report on the Results of Treatment in Gynecological Cancer
    Richard T Penson
    Harvard Medical School, Boston, MA, USA
    Int J Gynaecol Obstet 95:S247-57. 2006
    ..The QOL issues facing gynecologic cancer patients, the use of validated QOL instruments, recent advances in the evaluation of interventions, and changes in concepts related to QOL are reviewed...
  23. ncbi A longitudinal study on quality of life after gynecologic cancer treatment
    Y M Chan
    Department of Obstetrics and Gynecology, University of Hong Kong, Hong Kong SAR, People s Republic of China
    Gynecol Oncol 83:10-9. 2001
    ..The objective was to describe the pattern of quality of life (QOL) over time and to assess the impact of age, symptoms, disease parameters, and treatment on the overall QOL...
  24. ncbi Detection of pelvic lymph node metastases in gynecologic malignancy: a comparison of CT, MR imaging, and positron emission tomography
    A D Williams
    Department of Imaging, Hammersmith Hospital, Imperial College School of Medicine, Du Cane Rd, London W12 0HS, United Kingdom
    AJR Am J Roentgenol 177:343-8. 2001
    ..The poor results of PET in the pelvis are attributed to urinary (18)F-FDG in the ureters or bladder, which may mask or imitate lymph node metastases...
  25. ncbi Magnetic resonance lymphography: a novel technique for lymph node assessment in gynecologic malignancies
    P Narayanan
    Department of Radiology, St Bartholomews Hospital, London, UK
    Cancer Biomark 5:81-8. 2009
    ..Magnetic resonance lymphography (MRL) using iron oxide nanoparticles is a new technique for lymph node assessment which has shown much promise. This article discusses the applications of MRL in the setting of gynecological malignancy...
  26. ncbi Tissue characterization in the female pelvis by means of MR imaging
    E S Siegelman
    Department of Radiology, University of Pennsylvania Medical Center, Philadelphia 19104 4283, USA
    Radiology 212:5-18. 1999
    ..Consideration of the tissue composition of various pathologic processes in the pelvis can result in more systematic approaches to image interpretation and thus narrow the differential diagnosis...
  27. ncbi Predictors of complications and hospital stay in gynecologic cancer surgery
    M M Dean
    Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Ochsner Clinic and Alton Ochsner Medical Foundation, New Orleans, Louisiana 70121, USA
    Obstet Gynecol 97:721-4. 2001
    ..This information can be used to coordinate preoperative and postoperative hospital care and be a reference for certain future disease management systems...
  28. ncbi Prognostic nutritional index in relation to hospital stay in women with gynecologic cancer
    J T Santoso
    Division of Gynecologic Oncology, University of Texas Medical Branch at Galveston, Galveston, USA
    Obstet Gynecol 95:844-6. 2000
    ..To estimate the prevalence of malnutrition, correlate it with length of hospital stay, and evaluate laboratory tools to define it in gynecologic oncology...
  29. ncbi Human papillomavirus 16 and 18 L1 serology compared across anogenital cancer sites
    J J Carter
    Program in Cancer Biology, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109-1024, USA
    Cancer Res 61:1934-40. 2001
    ....
  30. ncbi Gynecologic cancer patients' psychosocial needs and their views on the physician's role in meeting those needs
    B E Miller
    Section on Gynecologic Oncology, Department of Obstetrics and Gynecology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157, USA
    Int J Gynecol Cancer 13:111-9. 2003
    ..Most patients surveyed want physicians to take an active role in dealing with psychosocial needs...
  31. ncbi Association of complementary methods with quality of life and life satisfaction in patients with gynecologic and breast malignancies
    P A Fasching
    Department of Gynecology and Obstetrics, University of Erlangen, Universitaetsstrasse 21 23, 91054, Erlangen, Germany
    Support Care Cancer 15:1277-84. 2007
    ..Our interest was to evaluate the association between CAM use and the patients' quality of life/life satisfaction (QoL/LS)...
  32. ncbi The virtues and pitfalls of minimally invasive surgery for gynecological malignancies: an update
    J M Childers
    Arizona Oncology Associates, Tucson 8512, USA
    Curr Opin Obstet Gynecol 11:51-9. 1999
    ..The reader is updated by a review of the reports published over the past year and a half...
  33. ncbi Analysis of failed and complicated laparoscopy on a gynecologic oncology service
    G H Eltabbakh
    Gynecologic Oncology, University of Vermont, Burlington, Vermont 05401, USA
    Gynecol Oncol 74:477-82. 1999
    ..To assess the incidence of and factors that predict failed or complicated operative laparoscopy on a gynecologic oncology service...
  34. ncbi Psychosocial adjustment in gynecologic cancer survivors: a longitudinal study on risk factors for maladjustment
    Y M Chan
    Department of Obstetrics and Gynaecology, Queen Mary Hospital, Hong Kong SAR, China
    Gynecol Oncol 80:387-94. 2001
    ..038). CONCLUSION: Most patients adapted well. Patients at risk for psychosocial maladjustment include those who are treated surgically, less educated, and without religious belief...
  35. ncbi The impact of anemia and its treatment on patients with gynecologic malignancies
    Susana Campos
    Department of Medical Oncology, Dana Farber Cancer Center, Boston, MA 02115, USA
    Semin Oncol 29:7-12. 2002
    ..Therefore, epoetin alfa treatment should be considered in this patient population...
  36. pmc Major complications following exenteration in cases of pelvic malignancy: a 10-year experience
    Dariusz Wydra
    Department of Gynecology of Medical University of Gdansk, 80 402 Gdansk ul Kliniczna 1 A, Poland
    World J Gastroenterol 12:1115-9. 2006
    ..To analyze the major complications after exenteration of gynecological and rectal malignancies...
  37. ncbi Advancing women's cancer care. Report from the 37th Annual Meeting of the Society of Gynecologic Oncologists, Palm Springs, Calif., USA, March 22-26, 2006
    Joanie Mayer Hope
    Department of Obstetrics and Gynecology, New York University School of Medicine, New York, NY, USA
    Gynakol Geburtshilfliche Rundsch 46:214-7. 2006
  38. ncbi [Constitutive characteristics and change trend of gynecological malignant tumors in 8009 hospitalized patients in Guangxi Zhuang Autonomous Region]
    Wei Huang
    Department of Gynecologic Oncology, Affiliated Cancer Hospital of Medical University of Guangxi, Nanning, China
    Zhonghua Fu Chan Ke Za Zhi 42:22-5. 2007
    ..To investigate the constitutive characteristics and the change trend of gynecologic malignant tumors in hospitalized patients in Guangxi Zhuang Autonomous Region over the recent 20 years...
  39. ncbi Predictors of severe gastrointestinal toxicity after external beam radiotherapy and interstitial brachytherapy for advanced or recurrent gynecologic malignancies
    Mohit Kasibhatla
    Department of Radiation Oncology, Dartmouth Hitchcock Medical Center, Hanover, NH 03756, USA
    Int J Radiat Oncol Biol Phys 65:398-403. 2006
    ..0...
  40. ncbi Neoadjuvant chemotherapy in gynecological cancers
    A Ayhan
    Division of Gynecologic Oncology, Department of Obstetrics and Gynaecology, Faculty of Medicine, University of Hacettepe, Ankara, Turkey
    Eur J Gynaecol Oncol 27:11-5. 2006
    ..The number of studies concerning endometrial, vulvar and vaginal cancers are few in the area of neoadjuvant chemotherapy...
  41. ncbi Gynaecological malignancies in pregnancy: a review
    Martin K Oehler
    Department of Gynaecological Oncology, Westmead Hospital, University of Sydney, Westmead, New South Wales, Australia
    Aust N Z J Obstet Gynaecol 43:414-20. 2003
    ..In the present review, recent diagnostic and treatment strategies for cervical, ovarian, vulvar and endometrial carcinomas during pregnancy are presented...
  42. pmc Expression analysis of mammaglobin A (SCGB2A2) and lipophilin B (SCGB1D2) in more than 300 human tumors and matching normal tissues reveals their co-expression in gynecologic malignancies
    Menelaos Zafrakas
    Institute of Pathology, University Hospital Aachen, RWTH Aachen, Pauwelsstrasse 30, 52074 Aachen, Germany
    BMC Cancer 6:88. 2006
    ....
  43. ncbi [Malignant tumors of the female genital track in the elderly]
    Leszek Gottwald
    I Kliniki Ginekologii i Onkologii Ginekologicznej Instytutu Ginekologii i Połoznictwa Uniwersytetu Medycznego w łodzi
    Ginekol Pol 74:714-7. 2003
    ..The coexisting another diseases often limits the possibility of the operative treatment in those cases...
  44. ncbi Laparoscopy and oncology: where do we stand today?
    Theodoros D Theodoridis
    First Department of Obstetrics and Gynaecology, Aristotle University of Thessaloniki, Hippokration Hospital, 8 Agias Theodoras Street, 546 42 Thessalonoki, Greece
    Ann N Y Acad Sci 997:282-91. 2003
    ..Until results from these trials are available, laparoscopic oncologic procedures should be performed only in an investigational setting by expert teams...
  45. pmc Differential DNA methylation profiles in gynecological cancers and correlation with clinico-pathological data
    Hui Juan Yang
    Department of Gynecologic Oncology, Fudan University Cancer Hospital, Shanghai, China
    BMC Cancer 6:212. 2006
    ..The abnormal promoter methylation might be a potential molecular marker for cancer management...
  46. ncbi Laparoscopic paraaortic left-sided transperitoneal infrarenal lymphadenectomy in patients with gynecologic malignancies: technique and results
    Christhardt Köhler
    Department of Obstetrics and Gynecology, Friedrich Schiller University, Bachstrasse 18, 07740, Jena, Germany
    Gynecol Oncol 91:139-48. 2003
    ..We evaluated whether left-sided paraaortic inframesenteric lymphadenectomy can be extended up to the left renal vein by laparoscopy...
  47. ncbi Fertility preservation options for women with malignancies
    Enbal Marhhom
    Department of Obstetrics and Gynecology, Sapir Medical Center, Kfar Saba, Sackler Faculty of Medicine, Tel Aviv University, Israel
    Obstet Gynecol Surv 62:58-72. 2007
    ....
  48. ncbi Predictors for long-term survival after interdisciplinary salvage surgery for advanced or recurrent gynecologic cancers
    M C Fleisch
    Universitaets Frauenklinik, Heinrich Heine Universitaet, Duesseldorf, Germany
    J Surg Oncol 95:476-84. 2007
    ..We wanted to identify factors which allow predicting long-term survival after pelvic exenteration (PE) for locally advanced or recurrent gynecologic malignancies...
  49. ncbi Malignant tumours of female genital tract in North Eastern Nigeria
    O Kyari
    Department of Obstetric and Gynaecology, Maiduguri Teaching Hospital, P M B 1414, Maiduguri, Nigeria
    East Afr Med J 81:142-5. 2004
    ..To ascertain the pattern and frequency of malignant tumours of female genital tract in North Eastern Nigeria...
  50. ncbi Hormonal replacement therapy after gynaecological cancer
    Nicoletta Biglia
    Institute for Cancer Research and Treatment IRCC, Academic Department of Gynaecological Oncology, University of Turin, Candiolo, Italy
    Gynakol Geburtshilfliche Rundsch 46:191-6. 2006
    ..The use of HRT in breast cancer patients is, at present, considered contra-indicated, even if results of clinical trials are not concordant. Therapeutic non-hormonal alternatives may be proposed to these patients...
  51. ncbi Pharmacokinetics and tumor uptake of a derivatized form of paclitaxel associated to a cholesterol-rich nanoemulsion (LDE) in patients with gynecologic cancers
    Maria L N Dias
    Department of Gynecology, Medical School Hospital, University of Sao Paulo, Sao Paulo, Brazil
    Cancer Chemother Pharmacol 59:105-11. 2007
    ..Here, the pharmacokinetics of LDE-paclitaxel oleate and the ability of LDE to concentrate the drug in the tumor were investigated in patients with gynecologic cancers...
  52. ncbi [Hereditary predispositions to gynaecological cancers]
    I Coupier
    Service de Genetique Medicale, Inserm 540, CHU de Arnaud de Villeneuve, 371, avenue du Doyen Gaston Giraud, 34295 Montpellier Cedex, France
    Gynecol Obstet Fertil 33:851-6. 2005
    ..An individual and family medical management ranging from simple monitoring to prophylactic surgery is proposed to these predisposed people...
  53. ncbi Ureteral surgery performed by a university gynecologic oncology service
    Mitchel S Hoffman
    University of South Florida, Division of Gynecologic Oncology, Tampa, FL, USA
    Am J Obstet Gynecol 195:562-6; discussion 566-7. 2006
    ....
  54. ncbi Audit of preoperative and early complications of laparoscopic lymph node dissection in 1000 gynecologic cancer patients
    Denis Querleu
    Institut Claudius Regaud Cancer Center, Toulouse, France
    Am J Obstet Gynecol 195:1287-92. 2006
    ..Establish the reliability and safety of minimal invasive surgery in gynecologic oncology in a large-scale study. Estimate the complication rate on a large sample size...
  55. ncbi Radical gynecologic surgery for cancer
    Sarah H Hughes
    Division of Gynecologic Oncology, Caritas St Elizabeth s Medical Center of Boston, 736 Cambridge Street, Boston, MA 02135 2997, USA
    Surg Oncol Clin N Am 14:607-31, viii. 2005
  56. ncbi Perioperative morbidity and mortality of gynecological oncologic surgery in elderly women
    I Ben-Ami
    Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Zerifin 70300, Israel
    Int J Gynecol Cancer 16:452-7. 2006
    ..Chronological age by itself should not be a contraindication for the treatment of elderly women with gynecological malignancy since it is a poor predicting factor for perioperative morbidity...
  57. ncbi Radiation therapy for gynecologic malignancies
    Kristin A Bradley
    Department of Human Oncology, University of Wisconsin Medical School, University Hospital and Clinics, K4 B100 Radiotherapy, 600 Highland Avenue, Madison, WI 53792, USA
    Hematol Oncol Clin North Am 20:347-61. 2006
    ....
  58. ncbi Surgical staging of gynecologic malignancies: the role of laparoscopy and sentinel node technology
    Robert Kim
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Cleveland Clinic Foundation, OH 44195, USA
    Surg Oncol Clin N Am 14:267-88. 2005
  59. ncbi New treatment concepts for gynecologic pelvic malignancies: neoadjuvant therapies
    Antonella Restivo
    Brown University, Providence, RI 02905, USA
    Surg Oncol Clin N Am 14:239-47. 2005
  60. ncbi Treatments for gynaecological cancers
    Sean Kehoe
    Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Best Pract Res Clin Obstet Gynaecol 20:985-1000. 2006
    ..This review will endeavour to focus on the evidence base, though inevitably, non-evidence based practice is unavoidable...
  61. ncbi p16 expression in the female genital tract and its value in diagnosis
    Ciaran J O'Neill
    Department of Pathology, Royal Group of Hospitals Trust, Grosvenor Road, Belfast BT12 6BL, Northern Ireland
    Adv Anat Pathol 13:8-15. 2006
    ..Some ovarian serous carcinomas, similar to their uterine counterparts, are p16-positive...
  62. ncbi Gonadotropin-releasing hormone (GnRH) agonist triptorelin inhibits estradiol-induced serum response element (SRE) activation and c-fos expression in human endometrial, ovarian and breast cancer cells
    Carsten Gründker
    Department of Gynecology and Obstetrics, Georg August University, D 37099 Göttingen, Germany
    Eur J Endocrinol 151:619-28. 2004
    ..In this study, we demonstrate that the GnRH agonist triptorelin inhibits estradiol (E2)-induced cancer cell proliferation...
  63. ncbi [Endoscopic surgery for gynecologic malignancy--less invasive, more radical]
    Masaaki Andou
    Dept of Obstetrics and Gynecology, Takarazuka City Hospital
    Gan To Kagaku Ryoho 31:1494-500. 2004
    ..As for the long-term results, although the number of cases and the observation period are limited, at present the outcome does not differ greatly from the results of conventional laparotomy...
  64. ncbi Microsatellite instability in mitochondrial genome of common female cancers
    Y Wang
    Department of Obstetrics and Gynecology, Faculty of Medicine, University of Hong Kong, Pokfulam, Hong Kong SAR, China
    Int J Gynecol Cancer 16:259-66. 2006
    ..Furthermore, carriers of a germ-line T to C polymorphism at np 16189 could be more susceptible to breast cancer development in light of the higher frequency detected in cancer patients than in normal individuals...
  65. ncbi Comparison of mohs micrographic surgery and wide excision for extramammary Paget's disease
    William J O'Connor
    Department of Dermatology, Mayo Clinic, Scottsdale, Arizona Mayo Clinic, Rochester, Minnesota, USA
    Dermatol Surg 29:723-7. 2003
    ..Extramammary Paget's disease is a rare cutaneous adenocarcinoma that occurs in an apocrine gland distribution mainly in the anogenital region...
  66. ncbi Genetic abnormalities of cell proliferation, invasion and metastasis, with special reference to gynaecological cancers
    Gajanan V Sherbet
    School of Electrical, Electronic and Computer Engineering, Merz Court, University of Newcastle upon Tyne, Newcastle upon Tyne NE1 7RU, U K
    Anticancer Res 23:1357-71. 2003
    ..The clinical effectiveness and reliability of these genes as markers of cancer progression and predictors of disease prognosis have been evaluated...
  67. ncbi Radiation therapy for gynecologic cancer
    Krishnansu Sujata Tewari
    Division of Gynecologic Oncology, The University of California, Irvine 92868, USA
    J Obstet Gynaecol Res 28:123-40. 2002
  68. ncbi Risk of colorectal cancer in women with a prior diagnosis of gynecologic malignancy
    Radhika Srinivasan
    Department of Medicine, Division of Gastroenterology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    J Clin Gastroenterol 41:291-6. 2007
    ..Earlier studies regarding the risk of colorectal cancer (CRC) in women with a prior diagnosis of gynecologic malignancies have revealed conflicting results. We sought to further clarify this association...
  69. ncbi Gynecologic malignancies in older women
    R Mirhashemi
    Jackson Memorial Hospital, University of Miami, Familial Ovarian/Breast Cancer Center, Miami, Florida, USA
    Oncology (Williston Park) 15:580-6; discussion 592-4, 597-8. 2001
    ..The main considerations in the treatment of ovarian, endometrial, cervical, and vulvar cancer are discussed...
  70. ncbi Pathological findings of gynecologic organs obtained at female radical cystectomy
    Sam S Chang
    Department of Urologic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA
    J Urol 168:147-9. 2002
    ..We evaluated the pathological features of reproductive organs removed during exenteration to determine the incidence of malignant pathology in these organs and the need for removal...
  71. ncbi Clinical trials in gynecological cancer
    E L Trimble
    National Cancer Institute Cancer Therapy Evaluation Program, Bethesda, MD, USA
    Int J Gynecol Cancer 17:547-56. 2007
    ..Other critical issues include support from government and charities and government regulations...
  72. ncbi Neuroendocrine tumors of the genital tract
    J H Eichhorn
    James Homer Wright Pathology Laboratories, Massachusetts General Hospital, Boston 02114, USA
    Am J Clin Pathol 115:S94-112. 2001
    ..It is important to distinguish prostatic small cell carcinoma from poorly differentiated adenocarcinoma with small cells. Small cell neuroendocrine carcinomas also occur rarely in the scrotum, penis, and penile urethra...
  73. ncbi [Early diagnosis of gynaecologic and breast cancers]
    W Grzybowski

    Ginekol Pol 72:1465-72. 2001
    ..The majority of Polish women suffer from breast, cervix, ovary and endometrial cancer. This paper shows common and new methods in early diagnosis of neoplasmic diseases...
  74. ncbi Colorectal stents for palliation of large-bowel obstructions in recurrent gynecologic cancer: an updated series
    Aileen Caceres
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Gynecol Oncol 108:482-5. 2008
    ..Our objective was to review and update our experience with colonic stent placement for patients presenting with a large-bowel obstruction due to recurrent gynecologic malignancy...
  75. ncbi Diet and environmental carcinogenesis in breast/gynaecological cancers
    Cristina Bosetti
    Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    Curr Opin Obstet Gynecol 14:13-8. 2002
    ..Alcohol appears to be related to the risk of breast cancer and overweight is associated with post-menopausal breast cancer and is strongly related to the risk of endometrial cancer...
  76. ncbi Continent ileocolonic urinary diversion (Rome pouch) for gynecologic malignancies: technique and feasibility
    Pierluigi Benedetti Panici
    Department of Obstetrics and Gynecology, La Sapienza University of Rome, Viale del Policlinico 155, 00161 Rome, Italy
    Gynecol Oncol 107:194-9. 2007
    ..To describe the technique, feasibility and early complications of "Rome pouch" urinary diversion...
  77. ncbi Hemostatic effects of high-dose megestrol acetate therapy in patients with advanced gynecological cancer
    C Oberhoff
    University Hospital Essen, Center of Gynecology and Obstetrics, Department of Gynecological Oncology, Hufelandstr. 55, D-45122 Essen, Germany
    Gynecol Endocrinol 15:341-8. 2001
    ..The observed incidence of thrombosis might be the consequence of other risk factors such as tumor-induced hypercoagulability, simultaneous chemotherapy or other individual thrombosis risk factors...
  78. ncbi Heat shock protein expression and immunity: relevance to gynecologic oncology
    S S Witkin
    Department of Obstetrics and Gynecology, Weill Medical College of Cornell University New York, New York 10021, USA
    Eur J Gynaecol Oncol 22:249-56. 2001
    ..The possible exploitation of the properties of heat shock proteins for development of unique anti-cancer therapies in individuals resistant to traditional treatment is currently under active investigation...
  79. ncbi Radiographic imaging in gynecologic oncology
    J T Soper
    Division of Gynecologic Oncology, Box 3079, Duke University Medical Center, Durham, NC 27710, USA
    Clin Obstet Gynecol 44:485-94. 2001
    ..Further refinements of currently available techniques or newer techniques, however, are needed to increase the sensitivity for detection of subclinical or microscopic metastases in patients with gynecologic malignancies...
  80. ncbi Urologic function and urodynamic evaluation of urinary diversion (Rome pouch) over time in gynecologic cancers patients
    Roberto Angioli
    Department of Obstetrics and Gynecology, Campus Bio Medico, University of Rome, Rome, Italy
    Gynecol Oncol 107:200-4. 2007
    ....
  81. ncbi Gynecologic cancers: factors affecting survival after pulmonary metastasectomy
    Jose M Clavero
    Division of General Thoracic Surgery, Rochester, Minnesota, USA
    Ann Thorac Surg 81:2004-7. 2006
    ..Little information is available regarding long-term survival after pulmonary metastasectomy for gynecologic malignancies...
  82. ncbi Explorative laparoscopy prior to exenterative surgery
    Christhardt Köhler
    Department of Gynecology, Friedrich Schiller University, Bachstrasse 18, 07740 Jena, Germany
    Gynecol Oncol 86:311-5. 2002
    ..The objective of this study was to identify the advantages and limits of laparoscopy for assessment of eligibility for exenterative procedures in patients with gynecologic malignancies...
  83. ncbi Society of Gynecologic Oncologists Education Committee statement on risk assessment for inherited gynecologic cancer predispositions
    Johnathan M Lancaster
    H Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA
    Gynecol Oncol 107:159-62. 2007
    ..This commentary provides guidance on identification of patients who may benefit from hereditary cancer risk assessment for Hereditary Breast/Ovarian Cancer and the Lynch/Hereditary Non-Polyposis Colorectal Cancer syndrome...
  84. ncbi [Paclitaxel and carboplatin with or without pirarubicin (THP-ADR) as first line chemotherapy in elderly patients]
    Shoji Nagao
    Dept of Obstetrics and Gynecology, Okayama University Medical School
    Gan To Kagaku Ryoho 30:243-9. 2003
    ..The overall response rates were equivalent among elderly and younger patients (69% and 78%), respectively. The regimen consisting of paclitaxel and carboplatin without THP-ADR was applied safely to elderly patients...
  85. ncbi The prevalence of tumors of the breast and female genital tract in Italy
    M Sant
    Epidemiology Division, National Cancer Institute (INT, Milan, Italy
    Tumori 85:382-6. 1999
    ..The prevalence of corpus uteri cancer decreased slightly in the elderly only, whereas that of cervix uteri cancer decreased at all ages...
  86. ncbi Colorectal function preservation in posterior and total supralevator exenteration for gynecologic malignancies: an 89-patient series
    V Moutardier
    Institut J Paoli l Calmettes and Université de la Méditerranée, 232 Bd de Sainte Marguerite, 13009 Marseille, France
    Gynecol Oncol 89:155-9. 2003
    ..The objective of this study was to analyze our experience with colorectal function preservation at the time of pelvic exenteration...
  87. ncbi [Endoscopic management of gynecological malignancies: an update. 2007]
    Michel Canis
    Gynécologie Obstétrique et Médecine de la Reproduction, université d Auvergne Clermont 1, Polyclinique de l Hotel Dieu, CHU de Clermont Ferrand
    Bull Acad Natl Med 191:1357-65; discussion 1365-6. 2007
    ..An excellent knowledge of the principles of endoscopy and of oncologic surgery is required. Training in endoscopic oncological techniques will be a major challenge in the field of gynecologic surgery in coming years...
  88. ncbi Mesna, doxorubicin, ifosfamide, and dacarbazine (MAID) chemotherapy for gynecological sarcomas
    M L Pearl
    Division of Gynecologic Oncology, Department of Obstetrics, Gynecology and Reproductive Medicine, State University of New York at Stony Brook, Stony Brook, New York, USA
    Int J Gynecol Cancer 12:745-8. 2002
    ..It remains to be established if any combination chemotherapy regimen is better than single agent treatment...
  89. ncbi Prospective evaluation of contrast-enhanced MRI in the depiction of peritoneal spread in primary or recurrent ovarian cancer
    Jens Ricke
    Department of Radiology, Charite Virchow Klinikum, Medical Faculty, Humboldt University, Augustenburgerplatz 1, 13353 Berlin, Germany
    Eur Radiol 13:943-9. 2003
    ..Magnetic resonance imaging based on contrast-enhanced fat-saturated T1 SE sequences improves planning of cytoreduction preceding chemotherapy in advanced primary or relapsed ovarian carcinoma...
  90. ncbi Small cell carcinoma of the female genital tract
    Sara Crowder
    Mid Missouri Gynecologic Oncology, Columbia, MO 65201, USA
    Semin Oncol 34:57-63. 2007
    ..Indeed, the majority of patients have an early demise with extensive distant disease. We review the clinical features, evaluation, and management of SCC of the female genital tract based on a comprehensive review of the literature...
  91. ncbi Inherited risk of women's cancers: what's changed for the practicing physician?
    Thomas S Frank
    Myriad Genetic Laboratories, Salt Lake City, Utah, USA
    Clin Obstet Gynecol 45:671-83; discussion 730-2. 2002
  92. ncbi [Gynecological cancers and pregnancy: the point of view of the oncology gynecologist]
    Philippe Morice
    Institut Gustave Roussy, 39, rue Camille Desmoulins, 94805 Villejuif
    Bull Cancer 89:765-71. 2002
    ..But such management needs to be determined in a multidisciplinary staff with oncologists, neonatologists, obstetricians but also the point of view of the patient...
  93. ncbi Serous papillary adenocarcinoma of the female genital organs and invasive micropapillary carcinoma of the breast. Are WT1, CA125, and GCDFP-15 useful in differential diagnosis?
    Suzuko Moritani
    Department of Pathology and Clinical Laboratories, Nagoya Medical Center, Nagoya, Aichi 460 0001, Japan
    Hum Pathol 39:666-71. 2008
    ..However, the availability of GCDFP-15 is limited because of the low positive rate of GCDFP-15 in invasive micropapillary carcinomas...
  94. ncbi Successful administration of carboplatin in patients with clinically documented carboplatin hypersensitivity
    Peter G Rose
    Case Western Reserve University, Ireland Cancer Center, Cleveland, OH 44106, USA
    Gynecol Oncol 89:429-33. 2003
    ....
  95. ncbi Occupational female breast and reproductive cancer mortality in British Columbia, Canada, 1950-94
    Amy C MacArthur
    Cancer Control Research Program, BC Cancer Agency, Vancouver, BC V5Z 1L3, Canada
    Occup Med (Lond) 57:246-53. 2007
    ..It has been postulated that recent increases in female breast and reproductive cancers may be, in part, attributable to occupational exposures...
  96. ncbi Trace elements analysis of ascitic fluid in benign and malignant diseases
    Handan Ak Celik
    Department of Biochemistry, Ege University School of Medicine, Bornova 35100 Izmir, Turkey
    Clin Biochem 35:477-81. 2002
    ..To evaluate differences in ascitic fluid trace element concentrations which might be useful in discrimination between benign and malignant ascites...
  97. ncbi Estrogen receptor alpha (ER-alpha) and beta (ER-beta) mRNAs in normal ovary, ovarian serous cystadenocarcinoma and ovarian cancer cell lines: down-regulation of ER-beta in neoplastic tissues
    A W Brandenberger
    Reproductive Endocrinology Center, University of California, San Francisco, 94143 0556, USA
    J Clin Endocrinol Metab 83:1025-8. 1998
    ..HEY did not contain detectable amounts of either ER after 40 cycles of RT-PCR. We found no evidence of differential splicing or major deletions in almost the entire coding region of ER-beta in either normal ovaries or tumor samples...
  98. ncbi Papillary serous carcinoma of the peritoneum coexisting with or after endometrial carcinoma
    Marco M Altaras
    Gynecologic Oncology Unit of the Department of Obstetrics and Gynecology, Meir Hospital, Kfar Saba 44281, Israel
    Gynecol Oncol 84:245-51. 2002
    ..The aim of this investigation was to describe our experience in treating five patients diagnosed with PSCP synchronously with EC and two others who developed PSCP metachronously after EC...
  99. ncbi Sexual dysfunction in patients with gynecologic neoplasms: a retrospective pilot study
    Alison Amsterdam
    Department of Surgery, Division of Gynecology, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Sex Med 3:646-9. 2006
    ..Little is known regarding the impact of a sexual health program on the sexual functioning of patients with a history of a gynecologic malignancy...
  100. ncbi Practice patterns of radiotherapy in endometrial cancer among member groups of the gynecologic cancer intergroup
    William Small
    RTOG, Philadelphia, PA, USA
    Int J Gynecol Cancer 19:395-9. 2009
    ..To describe radiotherapeutic practice of the treatment of endometrial cancer in members of the Gynecologic Cancer Intergroup (GCIG)...
  101. ncbi Fine-needle aspiration cytology of malignant fibrothecoma of the ovary
    G C Yang
    Department of Pathology, New York University Medical Center, New York, New York 10016, USA
    Diagn Cytopathol 21:284-6. 1999
    ..Cytodiagnosis of nonepithelial ovarian neoplasms can be difficult. However, it is not impossible, especially for recurrent tumors with previously established histodiagnosis. Diagn. Cytopath. 21:284-286, 1999...

Research Grants62

  1. HER-2 NEU PROTO-ONCOGENE IN OVARIAN & ENDOMETRIAL CANCER
    Michael Press; Fiscal Year: 1993
    ..the HER-2/neu proto-oncogene is clinically important in human gynecologic neoplasms and to understand the mechanisms by which this cellular oncogene regulates the metabolism of normal and malignant cells of the female reproductive tract..
  2. GYNECOLOGIC ONCOLOGY GROUP
    James Thigpen; Fiscal Year: 1980
    ..Current input is significant in all 4 of these areas as is documented in this application. ..
  3. CYCLIC GMP LEVELS IN GYNECOLOGIC NEOPLASMS
    Chandralekha Duttagupta; Fiscal Year: 1980
    ....
  4. Facilitating Informed Decisions for MSI Testing
    Sharon Manne; Fiscal Year: 2008
    ..The CD-ROM intervention will be developed with a view towards future dissemination. ..
  5. Tailored Intervention for Melanoma Patients' Families
    Sharon Manne; Fiscal Year: 2008
    ..396 family members will complete the study. Outcomes will be evaluated in terms of TCE, SSE and sun protection habits, as well as changes in attitudes and knowledge about CMM [unreadable] [unreadable]..
  6. Colon Cancer Screening for Cancer Patients' Families
    Sharon Manne; Fiscal Year: 2006
    ..After receiving the intervention information, participants will be interviewed again six months later regarding CRC screening behaviors and attitudes to assess the impact of the intervention. ..
  7. Improving Patient Adherence to Cancer Treatment
    Kathleen Ell; Fiscal Year: 2004
    ..5 IMPAACT intervention effects will be mediated by changes in targets of the components of the intervention, viz., strengthened intentions, reduced emotional barriers particularly depression, and reduced practical and system barriers. ..
  8. Multifaceted Depression Diabetes Program for Hispanics
    Kathleen Ell; Fiscal Year: 2008
    ..e., diet, exercise, checking blood glucose, and taking diabetic medication), decreased HbA1c levels and diabetes symptoms; and c) will improve function and satisfaction with diabetic and depression care vs. UC. ..
  9. Healing Touch, Immunity, and Fatigue in Breast Cancer
    Susan Lutgendorf; Fiscal Year: 2004
    ....
  10. Biobehavioral-Cytokine Interactions in Ovarian Cancer
    Susan Lutgendorf; Fiscal Year: 2007
    ..Findings will have implications for innovative behavioral and pharmacological intervention strategies for ovarian cancer patients. ..
  11. Native Navigation across the Cancer Continuum in Comanche Nation
    Valerie S Eschiti; Fiscal Year: 2010
    ....
  12. Multifaceted Oncology Depression Program for Latinos
    Kathleen Ell; Fiscal Year: 2007
    ..UC. Secondary questions include what is the effect of MODP on symptoms such as pain and fatigue and functional impairment from these symptoms. ..
  13. Healing Touch and Immunity in Advanced Cervical Cancer
    Susan Lutgendorf; Fiscal Year: 2002
    ....
  14. Oncology Depression Program--Latinas with Cancer
    Kathleen Ell; Fiscal Year: 2002
    ....
  15. Tumor metastasis: Biobehavioral mechanisms
    Anil K Sood; Fiscal Year: 2009
    ....
  16. MRI of Fetal Ventriculomegaly: Morphology and Outcome
    Deborah Levine; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  17. ENHANCED EVALUATION OF FETAL CNS WITH ULTRAFAST MRI
    Deborah Levine; Fiscal Year: 2002
    ..Thus the results of this study could significantly decrease morbidity of fetuses with ventriculomegaly. ..
  18. Genetic and Epigenetic Markers in Ovarian Cancer
    Elizabeth Swisher; Fiscal Year: 2006
    ..These studies may identify new prognostic or diagnostic markers in ovarian cancer. Such markers could then be tested in prospective trials to determine their clinical utility. ..
  19. IMPROVING COMMUNICATION WITH IVF PATIENTS ABOUT RISKS SUCH AS MULTIPLE BIRTHS
    LINDA FRAZIER; Fiscal Year: 2008
    ..The new materials will also help couples who achieve pregnancy to manage risks for increased maternal and neonatal problems among IVF singletons and multiples. [unreadable] [unreadable] [unreadable]..
  20. Improving Employment among Gynecologic Cancer Survivors
    LINDA FRAZIER; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  21. Fas/FasL System In Normal Mammary Gland Development
    Gil Mor; Fiscal Year: 2003
    ..With an improved foundation of the normal mammary physiology, we can advance the understanding of breast cancer, allowing the development of effective strategies for its treatment and prevention. ..
  22. A Molecular Signature of Early Cervical Carcinoma
    Concepcion Diaz Arrastia; Fiscal Year: 2007
    ..I propose to identify a genomic and proteomic signature of cervical cancer that will predict the aggressive behavior of the tumor and function clinically to develop molecular-based treatment plans. ..
  23. Development of a Web Based Tobacco Cessation Curriculum
    John Spangler; Fiscal Year: 2007
    ..The ultimate goal will be to develop a highly portable tobacco cessation curriculum that can be used a variety of educational settings. ..
  24. TOXICOLOGY OF ENVIRONMENT CONTAMINANTS
    Stephen Safe; Fiscal Year: 2007
    ..The proposed training program will continue to provide trainees with a challenging academic and research environment that will prepare them for future careers in academic, industry and government. ..
  25. Prostate Cancer Immunotherapy
    Robert Darnell; Fiscal Year: 2007
    ..Our results should indicate whether this new approach to DC based, immunotherapy has a potential role in the treatment of prostatic cancer as well as other malignancies. ..
  26. c-Myc, growth factor and breast cancer
    Dezhong Liao; Fiscal Year: 2007
    ..abstract_text> ..
  27. International Collaborative HNC Research
    Elaine Smith; Fiscal Year: 2007
    ..This aim is to determine whether there is an easily administered, sensitive biomarker that can predict HPV-HR status in HNC tumors prior to therapy.. [unreadable] [unreadable] [unreadable]..
  28. SUPPRESSION OF HUMAN GLIOBLASTOMA CELL GROWTH BY CX43
    Ruo Pan Huang; Fiscal Year: 2002
    ..The elucidation of cx43 function involved in the tumor suppression with respect to activation of apoptosis eventually will provide a molecular basis for the development of anti-cancer compounds. ..
  29. Race/Ethnic Variability in survey Question Processing and Response
    Timothy Johnson; Fiscal Year: 2009
    ..This is an important goal, as health surveys are one of the key yardsticks by which public health disparities are measured. ..
  30. Colon Cancer Inhibition by a Class of PPARgamma Agonists
    Stephen Safe; Fiscal Year: 2009
    ..The proposed studies will provide mechanistic insights on PPARy-dependent inhibition of colon cancer and identify compounds for future clinical studies. ..
  31. Natural History of CIN2 in Adolescents
    Anna Barbara Moscicki; Fiscal Year: 2007
    ..S. and specifically assess how best to modify cytology-based screening, utilize HPV diagnostics, and tailor aoDrooriate follow-uo strategies for adolescents and vouna women diaanosed with CIN 2 ..
  32. Characterizing Mammalian Embryonic polyA Binding Protein
    Emre Seli; Fiscal Year: 2008
    ....
  33. Strategies Against HPV Related Genital Diseases in Women
    Bradley Monk; Fiscal Year: 2006
    ..It is expected that Dr. Monk will have obtained extramural funding for both his laboratory and clinical studies by the end of the period of support requested. ..
  34. ALKYL PCDFS--INHIBITION OF MAMMARY CANCER
    Stephen Safe; Fiscal Year: 2001
    ..Thus the proposed studies will define a new mechanism-based class of antiestrogens that can be used alone or in combination with tamoxifen for treatment of breast and endometrial cancer. ..
  35. Promoting Breast Cancer Screening Via Computer V Phone
    Victoria Champion; Fiscal Year: 2008
    ..Stage of mammography adoption will be tested using logistic regression with ordinal outcome. Traditional cost and marginal cost-effectiveness analyses are planned. ..
  36. Transcripitonal and Genetic Profiles in HNSCCs
    Elaine Smith; Fiscal Year: 2008
    ..abstract_text> ..
  37. International Symposium on Cancer Metastasis and the Lymphovascular System
    STANLEY LEONG; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  38. Effect of Continuous vs. Sequential Oral Contraception
    RICHARD LEGRO; Fiscal Year: 2004
    ..Therefore, the risks and benefits of a CCOCP regimen are an important women's health issue that warrant investigation. ..
  39. Mechanisms of Growth Factor-Estrogen Receptor Crosstalk
    Stephen Safe; Fiscal Year: 2006
    ..abstract_text> ..
  40. Symposium on Cancer Metastasis and Lymphovascular System
    STANLEY LEONG; Fiscal Year: 2004
    ..abstract_text> ..
  41. Variations in plasma phytoestrogen levels in Europe
    Petra Peeters; Fiscal Year: 2004
    ..This pilot study will determine whether the variation of phytoestrogen concentrations in the European EPIC population is sufficient to justify further large-scale prospective nested case-control studies. ..
  42. NATURAL HISTORY OF HPV--INFECTION TO NEOPLASIA
    Anna Barbara Moscicki; Fiscal Year: 2004
    ..The understanding of both local and systemic immune responses to initial and subsequent HPV infections may be key in vaccine or therapeutic developments. ..
  43. ESTROGEN INDUCED RESPONSES VIA ER/SPL COMPLEXES
    Stephen Safe; Fiscal Year: 2002
    ..These results will ultimately facilitate design of chemotherapeutic approaches which target specific genes. ..
  44. GENETIC EPIDEMIOLOGY AND MECHANISMS IN ORAL CANCER
    Elaine Smith; Fiscal Year: 2003
    ..abstract_text> ..
  45. COMMUNITY INTERVENTION TO INCREASE MAMMOGRAPHY SCREENING
    Victoria Champion; Fiscal Year: 2003
    ..The primary outcomes at six month and 21 months will be tested by a chi-square statistic using logistic regression with two degrees of freedom. Cost effectiveness analysis is planned for the third aim. ..
  46. PHENOTYPIC AND PSYCHOSOCIAL STUDY OF THE L1307K MUTATION
    Henry Lynch; Fiscal Year: 2004
    ....
  47. EXERCISE INTERVENTION IN COLORECTAL POLYP PATIENTS
    Anne McTiernan; Fiscal Year: 2004
    ..Results from this unique human experimental study will provide important information about mechanisms of exercise effects on colon carcinogenesis and about potential ..
  48. Meeting of American Society for Reproductive Immunology:
    Gil Mor; Fiscal Year: 2003
    ..abstract_text> ..
  49. INSULIN RESISTANCE IN PCOS--SEQUELAE AND TREATMENT
    RICHARD LEGRO; Fiscal Year: 2005
    ..Improving insulin action through diet and exercise, with and without weight loss, will result in lowered circulating insulin levels, lowered androgens and increased ovulatory frequency rate in PCOS women. ..
  50. Protein arrays to profile cytokine expression in ovaria*
    Ruo Pan Huang; Fiscal Year: 2005
    ..The data will be analyzed using statistics and bioinformatics tool and correlated with pathological and clinical data. The successful outcome of this grant may impact on the development of new biomarkers for patient-care management. ..
  51. IMMUNE ACCEPTANCE OF PREGNANCY
    Gil Mor; Fiscal Year: 2002
    ..The significance of this proposal is not limited to reproductive problems. It is anticipated that these studies will lead to a better understanding of tumor behavior, actions of chemotherapeutic agents and transplant physiology. ..
  52. DOXYCYCLINE FOR BLEEDING IN PROGESTIN ONLY CONTRACEPTORS
    David Archer; Fiscal Year: 2006
    ..If successful, DOX treatment could become an important adjuvant for treatment of this and possibly other inflammatory disorders effecting reproductive tract tissues. ..
  53. Molecular Basis of Young Onset Colorectal Cancer
    Lisa Boardman; Fiscal Year: 2006
    ..Following achievement of these goals, I am confident that I will be ready to continue my career as a successful independent investigator committed to colerectal cancer prevention and control. ..
  54. CERVICAL CANCER--PREDICTIVE ASSAY BY MR IMAGING
    Nina Mayr; Fiscal Year: 2003
    ....
  55. Coactivation of Estrogen Receptor alpha/Sp1
    Stephen Safe; Fiscal Year: 2006
    ..abstract_text> ..
  56. 2,3,7,8,--TCDD Effects on the Estrogenic Responses
    Stephen Safe; Fiscal Year: 2006
    ..The proposed Aims will address important mechanistic considerations on IDRE-independent inhibitory AhR-ERa crosstalk and pathways critical for inhibition of mammary tumor growth by SAhRMs. ..
  57. Tolerance versus tumor immunity in PND
    Robert Darnell; Fiscal Year: 2005
    ..These experiments offer the possibility of developing new cancer treatments and advancing the understanding of autoimmune disease of the nervous system. ..
  58. PSYCHOLOGICAL INTERVENTION FOR WOMEN WITH BREAST CANCER
    BARBARA ANDERSEN; Fiscal Year: 2005
    ....
  59. Sexual Functioning and QOL in Women with Cervical Cancer
    Diane Bodurka; Fiscal Year: 2003
    ..Our long-term goal is to evaluate the effectiveness of such interventions in randomized trials. Ultimately, we hope to integrate our findings into daily clinical practice. ..
  60. Structure/function studies of RBPs in neurologic disease
    Robert Darnell; Fiscal Year: 2005
    ....
  61. Inhibition of Pancreatic Cancer by New PPARgamma Agonis*
    Stephen Safe; Fiscal Year: 2008
    ..PPAR? -active C-substituted DIMs that inhibit pancreatic cancer cell growth in vitro and in vivo, and these will serve as lead compounds for development of new drugs for clinical treatment of this devastating disease ..
  62. EXERCISE, DIET, AND SEX HORMONES IN POSTMENOPAUSAL WOMEN
    Anne McTiernan; Fiscal Year: 2008
    ..Intervention adherence will be monitored via exercise and diet logs and weekly weighing. Potential adverse effects will be measured including injuries, overall bone density (DEXA), and Quality of Life. ..