pleomorphic adenoma

Summary

Summary: A benign, slow-growing tumor, most commonly of the salivary gland, occurring as a small, painless, firm nodule, usually of the parotid gland, but also found in any major or accessory salivary gland anywhere in the oral cavity. It is most often seen in women in the fifth decade. Histologically, the tumor presents a variety of cells: cuboidal, columnar, and squamous cells, showing all forms of epithelial growth. (Dorland, 27th ed)

Top Publications

  1. ncbi Intraductal carcinoma is the precursor of carcinoma ex pleomorphic adenoma and is often associated with dysfunctional p53
    S Ihrler
    Institute of Pathology, Ludwig Maximilian University, Munich, Germany
    Histopathology 51:362-71. 2007
  2. ncbi Recurrent pleomorphic adenoma of the palate in a child
    H Shaaban
    Department of Plastic Surgery, Booth Hall Children's Hospital, Manchester M9 7AA, UK
    Br J Plast Surg 54:245-7. 2001
  3. ncbi Immunoprofile of reactive salivary myoepithelial cells in intraductal areas of carcinoma ex-pleomorphic adenoma
    Vera Cavalcanti de Araujo
    Department of Oral Pathology, São Leopoldo Mandic Dental Research Institute, Rua Abolição, 1827, 13041 445 Campinas, Sao Paulo, Brazil
    Oral Oncol 42:1011-6. 2006
  4. ncbi Salivary gland pleomorphic adenoma
    William M Mendenhall
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA
    Am J Clin Oncol 31:95-9. 2008
  5. ncbi Pleomorphic adenoma of the palate in children and adolescents: a report of 2 cases and review of the literature
    John Spencer M Daniels
    Department of Oral and Maxillofacial Surgery, Regional Dental Center, King Khalid Hospital, Najran, Saudi Arabia
    J Oral Maxillofac Surg 65:541-9. 2007
  6. pmc Management and prognostic factors of recurrent pleomorphic adenoma of the parotid gland: personal experience and review of the literature
    Luca Oscar Redaelli de Zinis
    Department of Otorhinolaryngology, University of Brescia, Piazza Spedali Civili 1, 25123 Brescia, Italy
    Eur Arch Otorhinolaryngol 265:447-52. 2008
  7. ncbi Immunohistochemical study of c-erbB-2 oncoprotein overexpression in human major salivary gland carcinoma: an indicator of aggressiveness
    S Sugano
    Pathology Division, National Cancer Center Research Institute, Tokyo, Japan
    Laryngoscope 102:923-7. 1992
  8. ncbi Bilateral choroidal metastasis from carcinoma ex pleomorphic adenoma of the parotid gland
    H Deniz Ilhan
    Department of Ophthalmology, Dokuz Eylul University, Izmir, Turkey
    Clin Experiment Ophthalmol 33:70-2. 2005
  9. ncbi Carcinoma ex pleomorphic adenoma of the submandibular gland with distant metastases
    D Hellin-Meseguer
    Department ENT, Vega Baja Hospital, Alicante, Spain
    B-ENT 3:27-9. 2007
  10. ncbi Recurrence of pleomorphic adenoma of the parotid gland--predictive value of cadherin-11 and fascin
    Juergen Brieger
    Department of Otorhinolaryngology, Head and Neck Surgery, Johannes Gutenberg University, Mainz, Germany
    APMIS 116:1050-7. 2008

Research Grants

  1. Validated Modeling and Culture of Salivary Cancers
    Wendell G Yarbrough; Fiscal Year: 2013
  2. PLAGL2 Expression in Emphysema Patient Lungs
    Yih Sheng Yang; Fiscal Year: 2009
  3. IMMUNOCHEMISTRY OF SALIVARY MUCINS IN DENTAL DISEASE
    Robert Cohen; Fiscal Year: 1992
  4. BR22, A Novel Protein Interacting with TTF-1
    Yih Sheng Yang; Fiscal Year: 2005

Detail Information

Publications280 found, 100 shown here

  1. ncbi Intraductal carcinoma is the precursor of carcinoma ex pleomorphic adenoma and is often associated with dysfunctional p53
    S Ihrler
    Institute of Pathology, Ludwig Maximilian University, Munich, Germany
    Histopathology 51:362-71. 2007
    Although intraductal carcinoma has been demonstrated in intracapsular carcinoma ex pleomorphic adenoma (CEPA), the morphological and genetic stages of transformation of pleomorphic adenoma (PA) to CEPA are not fully understood...
  2. ncbi Recurrent pleomorphic adenoma of the palate in a child
    H Shaaban
    Department of Plastic Surgery, Booth Hall Children's Hospital, Manchester M9 7AA, UK
    Br J Plast Surg 54:245-7. 2001
    A rare case of recurrent pleomorphic adenoma of the palate in a 9-year-old boy is presented. Pleomorphic adenoma is relatively rare in children compared with its incidence in adults...
  3. ncbi Immunoprofile of reactive salivary myoepithelial cells in intraductal areas of carcinoma ex-pleomorphic adenoma
    Vera Cavalcanti de Araujo
    Department of Oral Pathology, São Leopoldo Mandic Dental Research Institute, Rua Abolição, 1827, 13041 445 Campinas, Sao Paulo, Brazil
    Oral Oncol 42:1011-6. 2006
    ..We investigated the immunoprofile of benign MC in intraductal areas of carcinoma ex-pleomorphic adenoma (CXPA), comparing them with the MC in duct-like areas of pleomorphic adenoma, origin of the malignant tumor...
  4. ncbi Salivary gland pleomorphic adenoma
    William M Mendenhall
    Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, FL, USA
    Am J Clin Oncol 31:95-9. 2008
    We discuss the optimal treatment and outcomes for pleomorphic adenoma of the salivary glands by reviewing the pertinent literature. Pleomorphic adenoma is the most common benign salivary gland neoplasm...
  5. ncbi Pleomorphic adenoma of the palate in children and adolescents: a report of 2 cases and review of the literature
    John Spencer M Daniels
    Department of Oral and Maxillofacial Surgery, Regional Dental Center, King Khalid Hospital, Najran, Saudi Arabia
    J Oral Maxillofac Surg 65:541-9. 2007
  6. pmc Management and prognostic factors of recurrent pleomorphic adenoma of the parotid gland: personal experience and review of the literature
    Luca Oscar Redaelli de Zinis
    Department of Otorhinolaryngology, University of Brescia, Piazza Spedali Civili 1, 25123 Brescia, Italy
    Eur Arch Otorhinolaryngol 265:447-52. 2008
    The aim of this study was to investigate the management and prognostic determinants of recurrent pleomorphic adenoma (RPA)...
  7. ncbi Immunohistochemical study of c-erbB-2 oncoprotein overexpression in human major salivary gland carcinoma: an indicator of aggressiveness
    S Sugano
    Pathology Division, National Cancer Center Research Institute, Tokyo, Japan
    Laryngoscope 102:923-7. 1992
    ..Interestingly, positive results were obtained only in adenocarcinoma (6/20) and carcinoma in pleomorphic adenoma (7/15), and not in any other histological types such as adenoid cystic carcinoma, mucoepidermoid tumor, and ..
  8. ncbi Bilateral choroidal metastasis from carcinoma ex pleomorphic adenoma of the parotid gland
    H Deniz Ilhan
    Department of Ophthalmology, Dokuz Eylul University, Izmir, Turkey
    Clin Experiment Ophthalmol 33:70-2. 2005
    ..man with bilateral visual loss who had left parotidectomy with subsequent radiotherapy due to carcinoma ex pleomorphic adenoma of the parotid gland 1 year before...
  9. ncbi Carcinoma ex pleomorphic adenoma of the submandibular gland with distant metastases
    D Hellin-Meseguer
    Department ENT, Vega Baja Hospital, Alicante, Spain
    B-ENT 3:27-9. 2007
    A case of metastatic carcinoma ex pleomorphic adenoma (PA) of the submandibular gland is reported. While reports of local recurrence of this cancer are numerous, few cases of distant metastases have been reported...
  10. ncbi Recurrence of pleomorphic adenoma of the parotid gland--predictive value of cadherin-11 and fascin
    Juergen Brieger
    Department of Otorhinolaryngology, Head and Neck Surgery, Johannes Gutenberg University, Mainz, Germany
    APMIS 116:1050-7. 2008
    ..value of cadherin-11, tenascin, fascin, and mucin-1 as markers for the likelihood of recurrence in pleomorphic adenoma of the parotid gland was examined...
  11. ncbi Pleomorphic adenoma of the external auditory canal complicated by hearing loss secondary to chronic otitis media
    Kiyoaki Tsukahara
    Department of Otolaryngology, Tokyo Medical University, Tokyo, Japan
    Auris Nasus Larynx 33:183-6. 2006
    b>Pleomorphic adenoma (PA) rarely occurs in the external auditory canal (EAC). A case of PA complicated with chronic otitis media is reported...
  12. ncbi PLAG1 gene alterations in salivary gland pleomorphic adenoma and carcinoma ex-pleomorphic adenoma: a combined study using chromosome banding, in situ hybridization and immunocytochemistry
    Carmo Martins
    Centro de Investigacao de Patobiologia Molecular CIPM, Instituto Portugues de Oncologia de Francisco Gentil, Lisboa, Portugal
    Mod Pathol 18:1048-55. 2005
    b>Pleomorphic adenoma is the most common benign tumor of the salivary glands...
  13. ncbi Expression patterns and prognostic significance of inhibitor of apoptosis proteins in adenoid cystic carcinoma and pleomorphic adenoma of lachrymal gland
    Yongchuan Liao
    Department of Ophthalmology, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China
    Exp Eye Res 88:4-11. 2009
    ..Adenoid cystic carcinoma (ACC) of lachrymal gland is a malignant tumor with a poor prognosis, while, pleomorphic adenoma (PA) is the benign tumor of lachrymal gland epithelia...
  14. ncbi The significance of the margin in parotid surgery for pleomorphic adenoma
    Robert L Witt
    Section of Otolaryngology Head and Neck Surgery, Department of Surgery, Christiana Care Health Systems, Newark, Delaware, USA
    Laryngoscope 112:2141-54. 2002
    ..dramatically reduced the high rates of tumor recurrence that occurred with simple enucleation of parotid pleomorphic adenoma (PPA)...
  15. ncbi Histopathology of pleomorphic adenoma in the parotid gland: a prospective unselected series of 100 cases
    E Stennert
    Department of Otorhinolaryngology, University of Cologne, Koeln, Germany
    Laryngoscope 111:2195-200. 2001
    ....
  16. ncbi Carcinoma ex pleomorphic adenoma of the buccal region is composed of salivary duct carcinoma and squamous cell carcinoma components
    K Nakamori
    Department of Oral Surgery, Sapporo Medical University School of Medicine, Japan
    Int J Oral Maxillofac Surg 38:1116-8. 2009
    ..characteristics consistent with squamous cell carcinoma (SCC), salivary duct carcinoma (SDC) and pleomorphic adenoma (PA). The SCC nests showed no continuity with the buccal mucosa...
  17. ncbi Results of extracapsular dissection of pleomorphic adenoma of parotid gland
    Janusz Piekarski
    Department of Surgical Oncology, Medical University of Lodz, Ul Paderewskiego 4, 93 509 Lodz, Poland
    J Oral Maxillofac Surg 62:1198-202. 2004
    ....
  18. ncbi Pleomorphic adenoma of the submandibular gland: clinicopathological and immunohistochemical features of 60 cases in Brazil
    Fabio A Alves
    Hospital do Câncer Departamento de Cirurgia de Cabeça e Pescoço e Otorrinolaringologia, R Prof Antônio Prudente, 211, CEP 01509 900, Sao Paulo, Brazil
    Arch Otolaryngol Head Neck Surg 128:1400-3. 2002
    The submandibular gland is involved in only 5% to 10% of the salivary gland tumors, and pleomorphic adenoma (PA) is the most common tumor affecting it...
  19. ncbi Parapharyngeal space pleomorphic adenoma: a 30-year review
    Abie H Mendelsohn
    Division of Head and Neck Surgery, University of California Los Angeles School of Medicine, Los Angeles, California 90095, USA
    Laryngoscope 119:2170-4. 2009
    To evaluate the treatment results of pleomorphic adenoma (PA) of the parapharyngeal space at a single institution during a 30-year period.
  20. pmc Mucin expression in pleomorphic adenoma of salivary gland: a potential role for MUC1 as a marker to predict recurrence
    T Hamada
    Department of Maxillofacial Diagnostic and Surgical Science, Field of Oral and Maxillofacial Rehabilitation, Kagoshima University Graduate School of Medicine and Dental Sciences, 8 35 1 Sakuragaoka, Kagoshima 890 8544, Japan
    J Clin Pathol 57:813-21. 2004
    b>Pleomorphic adenoma of the salivary gland (PA) is essentially a benign neoplasm. However, patients with recurrent PA are difficult to manage...
  21. ncbi Differential diagnosis between adenoid cystic carcinoma and pleomorphic adenoma of the minor salivary glands of palate
    Giulio Cerulli
    Maxillofacial Surgery Department, I Faculty of Medicine and Surgery, University of Rome La Sapienza, Policlinic Umberto I, Rome, Italy
    J Craniofac Surg 15:1056-60. 2004
    ..A retrospective analysis in 24 patients with pleomorphic adenoma and adenoid cystic carcinoma of minor salivary glands of the palate was performed to investigate the ..
  22. ncbi Pleomorphic adenoma: extracapsular dissection versus partial superficial parotidectomy with facial nerve dissection
    Robert L Witt
    Head and Neck Multidisciplinary Clinic, Helen F Graham Cancer Center, USA
    Del Med J 81:119-25. 2009
    ..ECD does not dissect the facial nerve. PSP dissects the facial nerve and provides a 1-2 cm margin around the tumor...
  23. ncbi Carcinoma ex pleomorphic adenoma of the salivary gland: an immunohistochemical study
    Saori Matsubayashi
    Department of Otolaryngology, Tokyo Women s Medical University, Tokyo, Japan
    Eur Arch Otorhinolaryngol 264:789-95. 2007
    ..and sex steroid hormone receptors were investigated immunohistochemically in ten cases of carcinoma ex pleomorphic adenoma (Ca-ex-PA) of the salivary glands...
  24. ncbi Palatal pleomorphic adenoma in a child with osteoid formation: report of case
    Y K Chen
    School of Dentistry, Kaohsiung Medical College, Kaohsiung, Taiwan
    ASDC J Dent Child 65:209-11. 1998
    This paper reports a case of palatal pleomorphic adenoma in a Chinese child. The rare histologic feature of osteoid tissues is also presented.
  25. ncbi Pleomorphic adenoma of the nasal septum--a case report
    Swarna S Kumar
    Departments of Pathology and ENT, Vydehi Institute of Medical Science and Research Center, No 82, EPIP Area, Whitefield, Bangalore
    Indian J Pathol Microbiol 47:397-8. 2004
    b>Pleomorphic adenoma which is also called mixed tumour occur in major salivary glands like parotid and submandibular glands, and is rare in other sites such as the nasal cavity, pharynx, larynx, trachea and lacrimal glands...
  26. ncbi Primary pleomorphic adenoma of the external ear canal. Report of a case and literature review
    Konstantinos Markou
    Otolaryngology Department, AHEPA Hospital, Aristotle University of Thessaloniki, Greece
    Am J Otolaryngol 29:142-6. 2008
    ..skin of the external auditory meatus that may give rise to (a) benign tumors such as ceruminous adenoma, pleomorphic adenoma, and syringocystadenoma papilliferum, and (b) malignant tumors such as ceruminous adenocarcinoma, adenoid ..
  27. ncbi Role of limited parotidectomy in management of pleomorphic adenoma
    J T Johnson
    Department of Otolaryngology, School of Medicine, University of Pittsburgh, Pennsylvania, USA
    J Laryngol Otol 121:1126-8. 2007
    There is continued controversy over the extent of parotidectomy required for removal of a benign pleomorphic adenoma from the parotid gland...
  28. ncbi Pleomorphic adenoma of the breast
    Yuji Mizukami
    Department of Health Sciences, Graduate School of Medical Science, Kanazawa University, 5 11 80 Kodatsuno, Kanazawa, 920 0942, Japan
    Radiat Med 26:442-5. 2008
    b>Pleomorphic adenoma is a very rare benign tumor of the breast. Only 70 cases have been reported in the world literature...
  29. ncbi Expression of CD44V6 in parotid pleomorphic adenoma and carcinoma ex pleomorphic adenoma
    Sen Yang
    Sichuan University, China
    Expert Opin Investig Drugs 19:S101-8. 2010
    ..This pattern of expression might be associated with carcinogenesis of parotid pleomorphic adenoma (PPA) which is not widely studied...
  30. ncbi Carcinoma ex pleomorphic adenoma of the parotid gland. Study and implications for diagnostics and therapy
    Jan Christoffer Luers
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Cologne, Cologne, Germany
    Acta Oncol 48:132-6. 2009
    Carcinoma ex pleomorphic adenoma (CXPA) is a rare parotid malignancy and until today no standardized concept exists for its therapy apart from recommendations for parotid carcinoma in general...
  31. ncbi Juvenile intraoral pleomorphic adenoma: report of five cases and review of the literature
    J Jorge
    Department of Oral Pathology and Semiology, School of Dentistry of Piracicaba, University of Campinas, SP, Brazil
    Int J Oral Maxillofac Surg 31:273-5. 2002
    The aim of this study is to report on five cases of intraoral pleomorphic adenoma (PA) in patients under 18 years of age and to review the literature...
  32. ncbi Expressions of androgen receptor and its co-regulators in carcinoma ex pleomorphic adenoma of salivary gland
    Yoriko Nakajima
    Department of Plastic Surgery, Chiba University Graduate School of Medicine, Chuo Ku, Chiba, Japan
    Pathology 41:634-9. 2009
    ..The expression of AR has been reported in carcinoma ex pleomorphic adenoma (CXPA) of salivary gland, however AR gene status and the expressions of cofactors for AR signalling have ..
  33. ncbi Simultaneous primary pleomorphic adenoma in parotid gland and minor salivary gland in the parapharyngeal space
    S H Kim
    Department of Otolaryngology, National Medical Center, Seoul, Korea
    J Laryngol Otol 115:829-30. 2001
    ..Most of them are in the major salivary glands. The author reports the first case of simultaneous pleomorphic adenomas in the parotid gland and minor salivary gland at the parapharyngeal space...
  34. ncbi Glial fibrillary acidic protein and CD57 immunolocalization in cell block preparations is a useful adjunct in the diagnosis of pleomorphic adenoma
    Sejal S Shah
    Department of Pathology, SUNY Upstate Medical University, Syracuse, NY, USA
    Arch Pathol Lab Med 131:1373-7. 2007
    The cytologic distinction between pleomorphic adenoma (PA) and adenoid cystic carcinoma (ACC) can be diagnostically challenging in aspirate smears...
  35. ncbi Pleomorphic adenoma of the palate in a child: a case report
    Kittipong Dhanuthai
    Department of Oral Pathology, Faculty of Dentistry, Chulalongkorn University, Bangkok, Thailand
    Med Oral Patol Oral Cir Bucal 14:E73-5. 2009
    ..We reported the first case of palatal pleomorphic adenoma in a 13 year-old child from Thailand...
  36. ncbi Cytomorphologic spectrum of carcinoma ex pleomorphic adenoma
    Sonu Nigam
    Cytopathology Division, Department of Pathology, Maulana Azad Medical College and Lok Nayak Hospital, New Delhi, India
    Acta Cytol 48:309-14. 2004
    To delineate the cytomorphologic features of carcinoma ex pleomorphic adenoma (CPA) and identify the diagnostic pitfalls.
  37. ncbi Gray-scale and color Doppler ultrasonographic features of pleomorphic adenoma and Warthin's tumor in major salivary glands
    Wei Hsin Yuan
    Division of Radiology, Taipei Municipal Gan Dau Hospital T V G H, Taipei, Taiwan
    Clin Imaging 33:348-53. 2009
    Our aim was to assess the specific ultrasonic characteristics of pleomorphic adenoma and Warthin's tumor in major salivary glands.
  38. ncbi Inter- and intratumoral variability in magnetic resonance imaging of pleomorphic adenoma: an attempt to interpret the variable magnetic resonance findings
    Ken Motoori
    Departments of Radiology and Otolaryngology, Chiba University Hospital, Chiba, Japan
    J Comput Assist Tomogr 28:233-46. 2004
    The purpose of our study was to describe the various magnetic resonance (MR) findings of pleomorphic adenoma and to interpret these findings.
  39. ncbi Preoperative cytodiagnosis of pleomorphic adenoma with extensive lipometaplasia: a case report
    Neelaiah Siddaraju
    Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
    Acta Cytol 53:457-9. 2009
    b>Pleomorphic adenoma with extensive lipometaplasia is a rare, benign tumor of salivary gland origin...
  40. ncbi Malignant myoepithelioma arising from recurrent pleomorphic adenoma of the soft palate
    Alexandros D Karatzanis
    Department of Otorhinolaryngology, University of Crete School of Medicine, Heraklion, Crete, Greece
    Auris Nasus Larynx 32:435-7. 2005
    ..myoepithelioma is a rare salivary gland neoplasm that can arise either de novo or within a pre-existing pleomorphic adenoma. We report a case of malignant myoepithelioma arising from a pleomorphic adenoma of the soft palate...
  41. ncbi Transformation of pleomorphic adenoma to carcinoma ex pleomorphic adenoma of the parotid gland is independent of p53 mutations
    Claudia Gedlicka
    Department of Otorhinolaryngology, Medical University of Vienna, 1090 Vienna, Austria
    J Surg Oncol 101:127-30. 2010
    ..retrospective study was performed to evaluate the status of p53 in pleomorphic adenomas and carcinomas ex pleomorphic adenoma in the parotid gland...
  42. ncbi Characterization of the epithelial components in pleomorphic adenoma of the salivary gland
    Akihiko Kawahara
    Department of Pathology, Kurume University Hospital, Kurume University School of Medicine, Asahimachi, Kurume, Japan
    Acta Cytol 46:1095-100. 2002
    To clarify the cytomorphologic characteristics of luminal epithelial cells (LEC) and neoplastic myoepithelial cells (NMC) in pleomorphic adenoma (PA).
  43. ncbi Malignant plasmacytoid myoepithelioma of the palate: histological observations compared to benign predominant plasmacytoid myoepithelial cells in pleomorphic adenoma of the palate
    H Kuwabara
    Department of Pathology, Kagawa Medical University, Japan
    Ultrastruct Pathol 22:153-60. 1998
    Predominant benign plasmacytoid myoepithelial cells in pleomorphic adenoma and malignant plasmacytoid myoepithelioma cells were investigated morphologically. The cells of both tumors were plasmacytoid in appearance and sheet-like...
  44. ncbi Pleomorphic adenoma of the breast should be excised with a cuff of normal tissue
    Biku J John
    Department of Surgery, Mayday University Hospital, Croydon, Surrey, UK
    Breast J 13:418-20. 2007
    b>Pleomorphic adenoma is a benign tumor found rarely in the breast but commonly in the salivary gland. Unlike the salivary gland variant management guidelines are poorly defined in the breast...
  45. ncbi Pleomorphic adenoma of the vulva: a review illustrated by a clinical case
    R H M Dykgraaf
    Division of Gynaecology and Gynaecologic Oncology, Department of Obstetrics and Gynaecology, Erasmus MC Daniel den Hoed University Medical Center, Rotterdam, The Netherlands
    Int J Gynecol Cancer 16:920-3. 2006
    The pleomorphic adenoma of the vulva is an extremely scarce diagnosis. This form of neoplasm is more frequently observed in other topographic sites of the human body...
  46. ncbi Total-length invasion of the facial nerve by parotid carcinoma ex pleomorphic adenoma
    Takeshi Tsutsumi
    Department of Oto Rhino Laryngology, Dokkyo Medical University Koshigaya Hospital, Minami Koshigaya, Saitama, Japan
    Auris Nasus Larynx 36:618-22. 2009
    ..Pathological examination revealed the salivary duct carcinoma subtype of carcinoma ex pleomorphic adenoma. Within the facial nerve, the epineurium, perineurium and endoneurium were affected throughout its length...
  47. ncbi Prognostic factors of recurrence in salivary carcinoma ex pleomorphic adenoma, with emphasis on the carcinoma histologic subtype: a clinicopathologic study of 43 cases
    Nora Katabi
    Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY 10075, USA
    Hum Pathol 41:927-34. 2010
    Carcinoma ex pleomorphic adenoma is a rare salivary gland neoplasm, especially when the malignant component is only intracapsular/minimally invasive...
  48. ncbi Giant pleomorphic adenoma of the parotid gland
    Ademar Takahama
    Department of Oral Diagnosis, Piracicaba Dental School, University of Campinas, Brazil
    Med Oral Patol Oral Cir Bucal 13:E58-60. 2008
    b>Pleomorphic adenoma is the most common type of all benign and malignant salivary gland tumors, involving more frequently the parotid gland...
  49. ncbi Infarction after fine needle aspiration biopsy of pleomorphic adenoma of the parotid gland
    H Bayramoglu
    Department of Pathology, Pamukkale University Faculty of Medicine, Denizli, Turkey
    Acta Cytol 45:1008-10. 2001
    Fine needle aspiration (FNA) is a well-established and safe method for the rapid diagnosis of pleomorphic adenoma. A few clinically important complications, including bleeding, infection and inflammatory reactions, result from FNA...
  50. ncbi Expression of hormonal receptor in patients with metastasizing pleomorphic adenoma of the major salivary gland; a clinicopathological report of three cases
    Noppadol Larbcharoensub
    Department of Pathology, Faculty ofMedicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 92:1250-5. 2009
    Metastasizing pleomorphic adenoma is an uncommon malignant tumor of the salivary gland demonstrating benign epithelial and modified myoepithelial elements intermingling with tissue of mucoid, myxoid, or chondroid appearance that ..
  51. ncbi Pleomorphic adenoma of the upper lip in a child
    Mônica A Lotufo
    Department of Oral Diagnosis, School of Dentistry, Ibirapuera University, Sao Paulo, Brazil
    J Oral Sci 50:225-8. 2008
    This case report describes a rare and unusual lesion found in a 12-year-old boy, which was diagnosed as pleomorphic adenoma of the minor salivary glands in the upper lip. The tumor was a circumscribed, submucosal nodule, about 2...
  52. ncbi Expression of cyclooxygenase-2, Bcl-2 and Ki-67 in pleomorphic adenoma with special reference to tumor proliferation and apoptosis
    Takayuki Aoki
    Department of Oral Surgery, Tokai University School of Medicine, Bohseidai, Isehara, Kanagawa 259 1193, Japan
    Oral Oncol 40:954-9. 2004
    ..report is of immunohistochemical and cell biological studies on cyclooxygenase(COX)-2, Bcl-2 and Ki-67 in pleomorphic adenoma (n = 35)...
  53. ncbi Angiogenic and lymphangiogenic microvessel density in recurrent pleomorphic adenoma
    Andresa B Soares
    Centro de Pesquisa São Leopoldo Mandic, Rua José Rocha Junqueira 13 Ponte Preta, 13045 755, Campinas, SP, Brazil
    J Oral Pathol Med 38:623-9. 2009
    Recurrent pleomorphic adenoma (RPA) is an uncommon and challenging disease...
  54. ncbi Pleomorphic adenoma with mucinous and squamous differentiation: a mimicker of mucoepidermoid carcinoma
    S P Guo
    Department of Pathology, Xijing Hospital, The Fourth Military Medical University, Xian, China
    Int J Surg Pathol 17:335-7. 2009
    b>Pleomorphic adenoma with foci of squamous and mucinous differentiation can potentially be misdiagnosed as low-grade mucoepidermoid carcinoma...
  55. ncbi Giant pleomorphic adenoma of the parotid gland with malignant transformation
    Takashi Honda
    Tokyo Women s Medical University, Tokyo, Japan
    Ann Plast Surg 55:524-7. 2005
    ..examination revealed adenocarcinoma cells with hyperchromatic nuclei and mitotic figures proliferated in pleomorphic adenoma. Many authors have reported giant tumors weighing more than a few kilograms of the parotid glands, and most ..
  56. ncbi Polymorphous low-grade adenocarcinoma versus pleomorphic adenoma of minor salivary glands: resolution of a diagnostic dilemma by immunohistochemical analysis with glial fibrillary acidic protein
    A E Curran
    University of Mississippi Medical Center, USA
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 91:194-9. 2001
    Differentiating polymorphous low-grade adenocarcinoma (PLGA) from pleomorphic adenoma (PA) in salivary gland biopsy specimens from the palatal region might be a diagnostic dilemma for the pathologist when tumors are cellular with minimal ..
  57. pmc Sustained response of carcinoma ex pleomorphic adenoma treated with trastuzumab and capecitabine
    Elad Sharon
    Lung and Upper Aerodigestive Cancer Research Group, Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, USA
    Head Neck Oncol 2:12. 2010
    Carcinoma ex pleomorphic adenoma is a rare histologic subtype of salivary gland cancer with an overall poor prognosis...
  58. ncbi Non-invasive (intracapsular) carcinoma ex pleomorphic adenoma: recognition of focal carcinoma by HER-2/neu and MIB1 immunohistochemistry
    S Di Palma
    Department of Histopathology, Royal Surrey County Hospital, University of Surrey, Guilford, UK
    Histopathology 46:144-52. 2005
    Non-invasive carcinoma ex pleomorphic adenoma is defined as a carcinoma arising within the boundaries of a pleomorphic adenoma (PA), but which fails to display invasion beyond the capsule of host PA...
  59. ncbi Expression of estrogen receptor, progesterone receptor, and insulin-like growth factor receptor-1 and of MIB-1 in patients with recurrent pleomorphic adenoma of the parotid gland
    Afina S Glas
    Department of Surgical Oncology, University Hospital Groningen, Groningen, The Netherlands
    Cancer 94:2211-6. 2002
    ....
  60. ncbi Lipomatous pleomorphic adenoma of parotid gland
    H Korkmaz
    Histopathology 40:487-8. 2002
  61. ncbi Pleomorphic adenoma of the lower lip: report of a case
    E W H To
    Division of Head and Neck, Plastic and Reconstructive Surgery, Department of Surgery, The Chinese University of Hong Kong, Hong Kong
    J Oral Maxillofac Surg 60:684-6. 2002
  62. ncbi Myxolipomatous pleomorphic adenoma: an unusual oral presentation
    Fumio Ide
    Department of Oral Pathology, Meikai University School of Dentistry, 1 1 Keyakidai, Sakado, Saitama 350 0283, Japan
    J Oral Pathol Med 33:53-5. 2004
    The first case of a myxoid variant of lipomatous pleomorphic adenoma arising in the intraoral minor salivary gland is presented...
  63. ncbi Carcinoma ex pleomorphic adenoma of the palatal minor salivary gland with extension into the nasopharynx
    M Furukawa
    Department of Otorhinolaryngology, Sendai National Hospital, 2 8 8 Miyagino Miyagino ku, Sendai 983 8520, Japan
    Auris Nasus Larynx 28:279-81. 2001
    Carcinoma ex pleomorphic adenoma presenting in the nasopharynx is extremely rare. We present a case of carcinoma ex pleomorphic adenoma occupying the nasopharynx and the soft palate in a 51-year-old woman...
  64. ncbi Pleomorphic adenoma with extensive adenoid cystic carcinoma-like cribriform areas of parotid gland
    Ikuko Ogawa
    Clinical Laboratory, Hiroshima University Dental Hospital, Hiroshima University, Japan
    Pathol Int 53:30-4. 2003
    We report an interesting case of pleomorphic adenoma (PA) with extensive adenoid cystic carcinoma (ACC)-like cribriform areas of parotid gland along with a discussion of the differential diagnosis...
  65. ncbi Metastatic benign pleomorphic adenoma. Report of a case and review of the literature
    Javier Rodríguez-Fernández
    Maxillofacial Dept, Hospital Universitari Joan XXIII, Tarragona, Spain
    Med Oral Patol Oral Cir Bucal 13:E193-6. 2008
    b>Pleomorphic adenoma (PA), originally called mixed tumour, is the most common neoplasm of the salivary glands and is generally accepted as benign biologically. Occasionally PA may give rise to metastasis...
  66. ncbi Accessory parotid gland carcinoma ex pleomorphic adenoma. Case study diagnosed by fine needle aspiration
    Dimitrios Tamiolakis
    Department of Cytopathology, General Hospital of Chania, Crete, Greece
    Stomatologija 11:37-40. 2009
    ..7% of all parotid gland tumors. Carcinoma ex pleomorphic adenoma arises from a pre-existing benign mixed tumor...
  67. ncbi Surgical techniques in the treatment of pleomorphic adenoma of the parotid gland: our experience and review of literature
    V Valentini
    Department of Maxillofacial Surgery, University of Rome, La Sapienza, Italy
    J Craniofac Surg 12:565-8. 2001
    This paper presents a retrospective study carried out on a sample of 100 patients affected by pleomorphic adenoma of the parotid gland and treated at the Department of Maxillofacial Surgery at the University of Rome "La Sapienza&..
  68. ncbi Expression of betacatenin in carcinoma in pleomorphic adenoma, pleomorphic adenoma and normal salivary gland: an immunohistochemical study
    Renata Falchete do Prado
    Post Graduate Student in Oral Pathology, School of Dentistry of São José dos Campos, UNESP, Brasil
    Med Oral Patol Oral Cir Bucal 11:E247-51. 2006
    ..The objective of this study was to detect the expression of beta-catenin in pleomorphic adenomas, carcinomas in pleomorphic adenomas and normal salivary glands to discuss its role in the development of these two lesions...
  69. ncbi Carcinoma ex pleomorphic adenoma (CXPA): immunoprofile of the cells involved in carcinomatous progression
    A Altemani
    Department of Oral Pathology MTM, NSA, School of Dentistry, University of Sao Paulo, Sao Paulo, Brazil
    Histopathology 46:635-41. 2005
    To characterize the cellular component in pleomorphic adenoma (PA) that undergoes malignant transformation in carcinoma ex pleomorphic adenoma (CXPA).
  70. ncbi [Pleomorphic adenoma of minor salivary glands]
    Piotr Cwalina
    Klinika Chorób Uszu, Nosa, Gardła i Krtani AM w Gdańsku
    Otolaryngol Pol 56:737-40. 2002
    b>Pleomorphic adenoma, a benign tumor often seen in ENT practice, arises either from minor as well from major salivary glands. 5-14% of tumors occur in minor glands. Sixteen cases of minor salivary gland pleomorphic adenomas are studied...
  71. ncbi Ossifying pleomorphic adenoma of the parotid gland: a case report and review
    H Kato
    Department of Radiology, Gifu University School of Medicine, Gifu, Japan
    Australas Radiol 51:B173-5. 2007
    b>Pleomorphic adenoma is the most common parotid gland neoplasm and occasionally arises from the deep lobe of the parotid gland with extension into the parapharyngeal space...
  72. ncbi Biomarker analysis in carcinoma ex pleomorphic adenoma at an early phase of carcinomatous transformation
    Leandro L L Freitas
    Department of Pathology, Medical Science Faculty, University of Campinas UNICAMP, Campinas, SP, Brazil
    Int J Surg Pathol 13:337-42. 2005
    Diagnostic criteria for intracapsular carcinoma ex pleomorphic adenoma (CXPA) are subjective and vary among authors...
  73. pmc Salivary gland-like tumours of the breast: surgical and molecular pathology
    M Pia-Foschini
    Department of Pathology, University of Bologna, at Ospedale Bellaria, Bologna, I 40139 Italy
    J Clin Pathol 56:497-506. 2003
    ..group comprises a spectrum of lesions ranging from "bona fide" benign (such as benign myoepithelioma and pleomorphic adenoma), to low grade malignant (such as adenoid cystic carcinoma, low grade adenosquamous carcinoma, and ..
  74. ncbi Magnetic resonance imaging of pleomorphic adenoma arising from the external auditory canal
    Chisako Masumura
    Department of Otolaryngology, Osaka University Medical School, Suita, Osaka, Japan
    J Laryngol Otol 117:908-9. 2003
    b>Pleomorphic adenoma arising from the external auditory canal is a very rare neoplasm, and there has been no report on magnetic resonance (MR) imaging of pleomorphic adenoma of the external auditory canal...
  75. ncbi Precancerous foci in pleomorphic adenoma of the salivary gland: recognition of focal carcinoma and atypical tumor cells by P53 immunohistochemistry
    Sachiko Ohtake
    Division of Oral Pathology, Department of Tissue Regeneration and Reconstruction, Niigata University Graduate School of Medical and Dental Sciences, Japan
    J Oral Pathol Med 31:590-7. 2002
    ..It is still controversial if atypical tumor cells scattered in salivary pleomorphic adenomas are precancerous and how carcinoma arises in pleomorphic adenomas...
  76. ncbi Metachronous bilateral pleomorphic adenoma of the parotid gland
    Sindeval José da Silva
    Department of Head and Neck Surgery, University Hospital, School of Medicine, Federal University of Uberlandia, Uberlandia, MG, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 101:333-8. 2006
    ..Only on the left side some facial nerve branches were removed that induced partial paralysis in the patient. A review of the pertinent literature is included...
  77. ncbi Carcinoma ex pleomorphic adenoma: a clinicopathologic review
    K D Olsen
    Department of Otorhinolaryngology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Head Neck 23:705-12. 2001
    BACKGROUND: Carcinoma ex pleomorphic adenoma (CXPA) is an aggressive, poorly understood salivary gland malignancy...
  78. ncbi Surgical treatment of recurrent pleomorphic adenoma of the parotid gland: a clinical analysis of 52 patients
    A S Glas
    Department of Surgical Oncology/Head and Neck Surgery, University Hospital, Groningen, P.O. Box 30.001, 9700RB The Netherlands
    Head Neck 23:311-6. 2001
    BACKGROUND: Surgical management of recurrent pleomorphic adenoma of the parotid gland has a considerable risk of facial nerve injury and a high re-recurrence rate. To obtain more insight into this issue we evaluated our experiences...
  79. ncbi Cyclin D1 and p16 expression in pleomorphic adenoma and carcinoma ex pleomorphic adenoma of the parotid gland
    R S Patel
    Sydney Head and Neck Cancer Institute, Sydney Cancer Centre, and University of Sydney, Gloucester House, Royal Prince Alfred Hospital, Camperdown, NSW, Australia
    Histopathology 51:691-6. 2007
    To compare cyclin D1 and p16(ink4) (p16) expression in normal tissue, pleomorphic adenoma (PA) and carcinoma ex pleomorphic adenoma (CXPA) of the parotid gland.
  80. ncbi Overexpression of cyclooxygenase-2 correlates with cytoplasmic HuR expression in salivary mucoepidermoid carcinoma but not in pleomorphic adenoma
    Nam Pyo Cho
    Department of Oral Pathology, School of Dentistry and Institute of Oral Bioscience, Chonbuk National University, Jeonju, Korea
    J Oral Pathol Med 36:297-303. 2007
    ..HuR is an mRNA-binding protein that controls the stability of certain transcripts including COX-2...
  81. ncbi Expression of epidermal growth factor receptor, transforming growth factor-alpha and Ki-67 in relationship to malignant transformation of pleomorphic adenoma
    Hideaki Katori
    Department of Otolaryngology, Yokohama, City Minato Red Cross Hospital, Yokohama, Japan
    Acta Otolaryngol 127:1207-13. 2007
    ..The data support the hypothesis that increased epidermal growth factor receptor (EGFR) and transforming growth factor (TGF)-alpha expression is associated with early events in malignant transformation of pleomorphic adenoma (PA).
  82. ncbi Promoter swapping between the genes for a novel zinc finger protein and beta-catenin in pleiomorphic adenomas with t(3;8)(p21;q12) translocations
    K Kas
    Laboratory for Molecular Oncology, University of Leuven, Belgium
    Nat Genet 15:170-4. 1997
    ..Activation of PLAG1 was also observed in an adenoma with a variant translocation t(8;15)(q12;q14). Our results indicate that PLAG1 activation due to promoter swapping is a crucial event in salivary gland tumourigenesis...
  83. ncbi Recurrent pleomorphic adenoma of the parotid gland: analysis of 108 consecutive patients
    Claus Wittekindt
    Clinic of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, D 50924 Cologne, Germany
    Head Neck 29:822-8. 2007
    Surgery for recurrent parotid pleomorphic adenoma is a challenging problem.
  84. ncbi Expression patterns of integrins on pleomorphic adenoma and adenoid cystic carcinoma: study on specimens and in vitro investigation of the effects of extracellular matrix on the expression of these adhesion molecules
    S V Lourenco
    Instituto de Medicina Tropical de São Paulo and Department of Dermatology, Medical School of the University of São Paulo, Sao Paulo, SP, Brazil
    J Oral Pathol Med 33:574-80. 2004
    b>Pleomorphic adenoma (PA) and adenoid cystic carcinoma (ACC) are neoplasms of distinct behaviour, showing similar origin, cell components and marked presence of extracellular matrix (ECM)...
  85. ncbi Pleomorphic adenoma arising in an accessory lacrimal gland of Wolfring
    Ghassan A Alyahya
    Eye Pathology Institute, University of Copenhagen, Copenhagen, Denmark
    Ophthalmology 113:879-82. 2006
    To describe a patient with pleomorphic adenoma arising in an accessory lacrimal gland of Wolfring in the lower lid and to illustrate the immunohistochemical and molecular cytogenetics.
  86. ncbi Increased expression of cyclooxygenase-2 and Ki-67 are associated with malignant transformation of pleomorphic adenoma
    Hideaki Katori
    Department of Otolaryngology, Yokohama City Minato Red Cross Hospital, 3 12 1 Shin Yamashita, Naka ku, Yokohama 231 8682, Japan
    Auris Nasus Larynx 34:79-84. 2007
    ..present study, we attempted to identify cyclooxygenase-2 (COX-2) expression and Ki-67 index in carcinoma ex-pleomorphic adenoma (Ca ex-PA) using quantitative immunohistochemical analysis and to compare the benign component of the ..
  87. pmc Oncocytic change in pleomorphic adenoma: molecular evidence in support of an origin in neoplastic cells
    Silvana Di Palma
    Royal Surrey County Hospital, University of Surrey, Guildford, UK
    J Clin Pathol 60:492-9. 2007
    ..When found within pleomorphic adenomas (PAs), cells with OC may be perceived as evidence of malignancy, and lead to a misdiagnosis of carcinoma ex pleomorphic adenoma (CaExPa).
  88. ncbi Cytologic findings of a pleomorphic adenoma of the breast: a case report
    Perikala V Kumar
    Department of Pathology, Shiraz Medical School, Shiraz, IR Iran
    Acta Cytol 48:849-52. 2004
    b>Pleomorphic adenoma of the breast is a rare benign tumor. Only a few cases have been reported. The histologic features have been described well. However, the cytologic findings have been described in only a few papers.
  89. ncbi Recurrent pleomorphic adenoma of the parotid gland
    John P Leonetti
    Loyola Center for Cranial Base Surgery, Maywood, IL 60153, USA
    Otolaryngol Head Neck Surg 133:319-22. 2005
    To assess the long-term results in the management of 42 patients with recurrent pleomorphic adenoma of the parotid gland.
  90. ncbi Metastasising pleomorphic adenoma of the parotid gland
    T Sabesan
    Department of Oral and Maxillofacial Surgery, Poole General Hospital, Longfleet Road, Poole, Dorset, UK
    Br J Oral Maxillofac Surg 45:65-7. 2007
    A 33-year-old man had a left superficial parotidectomy for a pleomorphic adenoma. He remained well, but 28 years later developed a metastasis in a lymph node in the left supraclavicular fossa.
  91. ncbi Endoscopic resection of pleomorphic adenoma arising in the nasopharynx
    Jong Lyel Roh
    Department of Otolaryngology Head and Neck Surgery, Cancer Research Institute, Chungnam National University College of Medicine, Daejeon, South Korea
    Acta Otolaryngol 125:910-12. 2005
    b>Pleomorphic adenoma is the commonest benign tumor of the salivary glands. It has rarely been reported arising in the nasopharynx...
  92. ncbi CNS metastases of carcinoma ex pleomorphic adenoma of the parotid gland
    S P Sheedy
    Department of Radiology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    AJNR Am J Neuroradiol 27:1483-5. 2006
    ..This case report presents the clinical and radiographic features of a rare case of biopsy proved brain and spinal cord metastases arising from carcinoma ex PA of the parotid gland...
  93. ncbi Nasopharyngeal pleomorphic adenoma in the adult
    Scott L Lee
    Division of Otolaryngology Head and Neck Surgery, Albany Medical Center, Albany, New York 12208 3420, USA
    Laryngoscope 116:1281-3. 2006
    Salivary gland tumors account for less than 5% of all neoplasms in the head and neck, with pleomorphic adenoma being the most common type...
  94. ncbi Recurrent pleomorphic adenoma of the parotid gland
    Evelyn Linda Maxwell
    Department of Otolaryngology Head Neck Surgery, University of Toronto, Mount Sinai Hospital, Toronto, ON
    J Otolaryngol 33:181-4. 2004
    This is a retrospective analysis of 35 patients treated for a first recurrence of pleomorphic adenoma of the parotid gland from 1982 to 1997. All patients were treated surgically; no patient received radiotherapy for benign disease...
  95. ncbi Pleomorphic adenoma of salivary gland: to what extent does fine needle aspiration cytology reflect histopathological features?
    D K Das
    Department of Pathology, Faculty of Medicine, Kuwait University, Kuwait
    Cytopathology 16:65-70. 2005
    The histological diversity encountered in pleomorphic adenoma may cause diagnostic difficulty in fine needle aspiration (FNA) cytology due to limited and selective sampling...
  96. ncbi Fine-needle aspiration biopsy of cystic pleomorphic adenoma with adnexa-like differentiation mimicking mucoepidermoid carcinoma: a case report
    Noman H Siddiqui
    Division of Cytopathology, Department of Pathology MC 847, University of Illinois Medical Center at Chicago, 1819 W Polk St, Room 446, Chicago, IL 60612, USA
    Diagn Cytopathol 32:229-32. 2005
    ..Presence of squamous, mucinous, and/or sebaceous metaplasia, especially in the absence of chondromyxoid stroma, presents the potential for misinterpretation of the FNAB as indicative of malignancy in general and MEC in particular...
  97. ncbi Recurrent pleomorphic adenoma of the parotid gland
    Peter Zbären
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital, University of Berne, CH 3010 Berne, Switzerland
    Am J Surg 189:203-7. 2005
    Surgery of recurrent pleomorphic adenoma presents an increased risk of facial nerve injury and a considerable re-recurrence rate.
  98. ncbi Stereotactic radiosurgery for recurrent pleomorphic adenoma invading the skull base--case report--
    Tohru Kamida
    Department of Neurosurgery, Oita University Faculty of Medicine
    Neurol Med Chir (Tokyo) 45:161-3. 2005
    A 38-year-old man presented with a recurrent pleomorphic adenoma in the parapharyngeal space invading the skull base 19 years after the first operation for a parotid gland tumor...
  99. ncbi Pleomorphic adenoma of the lacrimal gland. Case report
    Alejandro Ostrosky
    Servicio de Cirugia Maxilofacial, Hospital Mariano y Luciano de La Vega, Moreno, Buenos Aires, Argentina
    Med Oral Patol Oral Cir Bucal 10:88-9; 86-8. 2005
    ..We present a case of a 69 year old male patient with a one year history of an orbital tumor (Pleomorphic Adenoma)...
  100. ncbi Carcinoma ex-pleomorphic adenoma of the breast. Report of three cases suggesting a relationship to metaplastic carcinoma of matrix-producing type
    Malcolm M Hayes
    Department of Pathology, British Columbia Cancer Agency, Vancouver, BC, V5Z 4E6, Canada
    Virchows Arch 446:142-9. 2005
    Three cases of carcinoma ex-pleomorphic adenoma of the breast are reported. Patients were 82, 60 and 56 years old and presented with a breast lump...
  101. ncbi The role of postoperative radiation therapy in carcinoma ex pleomorphic adenoma of the parotid gland
    Allen M Chen
    Department of Radiation Oncology, University of California, San Francisco UCSF Comprehensive Cancer Center, San Francisco, CA
    Int J Radiat Oncol Biol Phys 67:138-43. 2007
    To evaluate the impact of postoperative radiation therapy on the clinical course of patients with carcinoma ex pleomorphic adenoma of the parotid gland.

Research Grants4

  1. Validated Modeling and Culture of Salivary Cancers
    Wendell G Yarbrough; Fiscal Year: 2013
    ..adenoid cystic, adenocarcinoma not otherwise specified, polymorphous low grade adenocarcinoma, carcinoma ex-pleomorphic adenoma, and salivary ductal carcinoma...
  2. PLAGL2 Expression in Emphysema Patient Lungs
    Yih Sheng Yang; Fiscal Year: 2009
    Abstract: Pleomorphic Adenoma Gene Like-2 (PLAGL2) was identified as a transactivator of surfactant protein C (SP-C)...
  3. IMMUNOCHEMISTRY OF SALIVARY MUCINS IN DENTAL DISEASE
    Robert Cohen; Fiscal Year: 1992
    ..These findings will then be compared with those found for neoplastic salivary gland tissues using pleomorphic adenoma, mucoepidermoid carcinoma, and adenocystic carcinoma as models...
  4. BR22, A Novel Protein Interacting with TTF-1
    Yih Sheng Yang; Fiscal Year: 2005
    ..Two-color or triple-color staining of endogenous proteins in H441 cells or the lung sections will be performed to detect their expression in SP-B producing cells. ..