multiple primary neoplasms

Summary

Summary: Two or more abnormal growths of tissue occurring simultaneously. The neoplasms are histologically different and may be found in the same or different sites.

Top Publications

  1. ncbi Malignant thymoma in the United States: demographic patterns in incidence and associations with subsequent malignancies
    Eric A Engels
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20892, USA
    Int J Cancer 105:546-51. 2003
  2. pmc The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers
    D A Lawes
    Department of Surgery, Royal Free and University College London, UK
    Br J Cancer 93:472-7. 2005
  3. ncbi Concordance of allelic imbalance profiles in synchronous and metachronous bilateral breast carcinomas
    Evgeny N Imyanitov
    N N Petrov Institute of Oncology, St Petersburg, Russia
    Int J Cancer 100:557-64. 2002
  4. ncbi Bladder cancer after managing upper urinary tract transitional cell carcinoma: predictive factors and pathology
    Jay D Raman
    Department of Urology, The New York Presbyterian Hospital, Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA
    BJU Int 96:1031-5. 2005
  5. ncbi Multiple primary malignant tumors in a national cancer registry--reliability of reporting
    J E Frodin
    Dept of Oncology Radiumhemmet, Karolinska Hospital, Stockholm, Sweden
    Acta Oncol 36:465-9. 1997
  6. ncbi Melanoma and nonmelanoma skin cancer in patients with multiple tumours--evidence for new syndromes in a population-based study
    K Nielsen
    Department of Dermatology, University Hospital, S 221 85 Lund, Sweden
    Br J Dermatol 150:531-6. 2004
  7. ncbi Clonal analysis of bilateral mammary carcinomas by clinical evaluation and partial allelotyping
    Gary M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong, People s Republic of China
    Am J Clin Pathol 120:168-74. 2003
  8. ncbi Multiple primary neoplasms at a single institution: differences between synchronous and metachronous neoplasms
    A Aydiner
    Department of Medical Oncology, Institute of Oncology, University of Istanbul, Turkey
    Am J Clin Oncol 23:364-70. 2000
  9. ncbi Bilateral testicular germ cell tumors: twenty-year experience at M. D. Anderson Cancer Center
    Mingxin Che
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Cancer 95:1228-33. 2002
  10. ncbi Photodynamic therapy of early squamous cell carcinomas of the esophagus: a review of 31 cases
    J F Savary
    Dept of Otolaryngology, Head and Neck Surgery, CHUV Hospital, Lausanne, Switzerland
    Endoscopy 30:258-65. 1998

Detail Information

Publications226 found, 100 shown here

  1. ncbi Malignant thymoma in the United States: demographic patterns in incidence and associations with subsequent malignancies
    Eric A Engels
    Viral Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Department of Health and Human Services, Rockville, MD 20892, USA
    Int J Cancer 105:546-51. 2003
    ..The peak in late adulthood deserves further study. Variation in incidence by race suggests a role for genetic factors. Our study did not demonstrate broadly increased risk for malignancies following thymoma...
  2. pmc The role of MLH1, MSH2 and MSH6 in the development of multiple colorectal cancers
    D A Lawes
    Department of Surgery, Royal Free and University College London, UK
    Br J Cancer 93:472-7. 2005
    ..We suggest that, although MSI-H is more commonly identified in those with multiple colorectal cancers, this does not commonly arise from a classical HNPCC pathway...
  3. ncbi Concordance of allelic imbalance profiles in synchronous and metachronous bilateral breast carcinomas
    Evgeny N Imyanitov
    N N Petrov Institute of Oncology, St Petersburg, Russia
    Int J Cancer 100:557-64. 2002
    ..014). Overall, our data suggest that sharing natural histories of the disease, which is more evident in synchronous and/or premenopausal forms of biBC, may result in a similarity of molecular portraits in bilateral breast tumors...
  4. ncbi Bladder cancer after managing upper urinary tract transitional cell carcinoma: predictive factors and pathology
    Jay D Raman
    Department of Urology, The New York Presbyterian Hospital, Weill Medical College of Cornell University, 525 East 68th Street, New York, NY 10021, USA
    BJU Int 96:1031-5. 2005
    ..To evaluate patients with a history of transitional cell carcinoma (TCC) of the upper urinary tract (UUT) to determine the incidence, pathological distribution, and risk factors for developing subsequent bladder tumours...
  5. ncbi Multiple primary malignant tumors in a national cancer registry--reliability of reporting
    J E Frodin
    Dept of Oncology Radiumhemmet, Karolinska Hospital, Stockholm, Sweden
    Acta Oncol 36:465-9. 1997
    ..The Swedish Cancer Registry, to which all newly diagnosed malignancies by law have to be reported, comprise today close to one million individuals with registered malignancies...
  6. ncbi Melanoma and nonmelanoma skin cancer in patients with multiple tumours--evidence for new syndromes in a population-based study
    K Nielsen
    Department of Dermatology, University Hospital, S 221 85 Lund, Sweden
    Br J Dermatol 150:531-6. 2004
    ..g. nonmelanoma skin cancer (NMSC), were studied descriptively. So far the mutation 113insArg explains all CDKN2A-associated CMM in ethnic Swedes...
  7. ncbi Clonal analysis of bilateral mammary carcinomas by clinical evaluation and partial allelotyping
    Gary M Tse
    Department of Anatomical and Cellular Pathology, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong, People s Republic of China
    Am J Clin Pathol 120:168-74. 2003
    ..No discrepant results were noted. Stringent application of clinical criteria is accurate for differentiating second primary tumors from metastases...
  8. ncbi Multiple primary neoplasms at a single institution: differences between synchronous and metachronous neoplasms
    A Aydiner
    Department of Medical Oncology, Institute of Oncology, University of Istanbul, Turkey
    Am J Clin Oncol 23:364-70. 2000
    ..Localization in the medial region and in the head/neck was more frequent in the synchronous group than in the case of metachronous secondary tumors...
  9. ncbi Bilateral testicular germ cell tumors: twenty-year experience at M. D. Anderson Cancer Center
    Mingxin Che
    Department of Pathology, The University of Texas M D Anderson Cancer Center, Houston 77030, USA
    Cancer 95:1228-33. 2002
    ..D. Anderson Cancer Center over a 20-year period with emphasis on their incidence, histologic features, and clinical features...
  10. ncbi Photodynamic therapy of early squamous cell carcinomas of the esophagus: a review of 31 cases
    J F Savary
    Dept of Otolaryngology, Head and Neck Surgery, CHUV Hospital, Lausanne, Switzerland
    Endoscopy 30:258-65. 1998
    ....
  11. ncbi Epidemiology of contralateral breast cancer
    Y Chen
    Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ontario, Canada
    Cancer Epidemiol Biomarkers Prev 8:855-61. 1999
    ..Additional analytical studies addressing all potential risk factors associated with the development of contralateral breast cancer are necessary in view of the increasing incidence and survival of women with a first primary...
  12. ncbi Contralateral breast cancer: molecular differentiation between metastasis and second primary cancer
    E Janschek
    Department of Surgery, University of Vienna, Austria
    Breast Cancer Res Treat 67:1-8. 2001
    ..We could also demonstrate that contralateral breast cancer spread does occur. Standard pathological assessment allowed a firm diagnosis only in the presence of different histological types...
  13. ncbi Drastic genetic instability of tumors and normal tissues in Turcot syndrome
    M Miyaki
    Department of Biochemistry, The Tokyo Metropolitan Institute of Medical Science, Japan
    Oncogene 15:2877-81. 1997
    ..Additional unknown germline mutation may contribute to the genetic instability in normal tissues...
  14. ncbi Four synchronous female genital malignancies: the ovary, cervix, endometrium and fallopian tube
    Arzu Saglam
    Department of Pathology, Hacettepe University School of Medicine, Ankara, Turkey
    Arch Gynecol Obstet 277:557-62. 2008
    ..To present a unique case of a 63 year-old woman with coexistent adenocarcinoma of the ovary, endometrium, cervix and fallopian tube...
  15. ncbi Increasing the diagnosis of multifocal primary breast cancer by the use of bilateral whole-breast ultrasound
    L S Wilkinson
    South West London Breast Screening Service, University College, London, UK
    Clin Radiol 60:573-8. 2005
    ..The aim of this study was to evaluate the contribution of bilateral whole-breast ultrasound (BBUS) to the diagnosis and management of women with newly diagnosed breast cancer...
  16. ncbi Clonality of multifocal urothelial carcinomas: 10 years of molecular genetic studies
    Christian Hafner
    Institute of Pathology, University of Regensburg, Germany
    Int J Cancer 101:1-6. 2002
    ..Investigation of the entire urothelial lining in patients with urothelial tumors should provide further insight into the development of multifocal urothelial carcinomas...
  17. ncbi Characteristics of synchronous- and metachronous-type multiple primary neoplasms: a study of hospital-based cancer registry in Turkey
    Sevil Kilciksiz
    Department of Radiation Oncology, Gaziantep University, Medical School, Gaziantep, Turkey
    Clin Genitourin Cancer 5:438-45. 2007
    The aim of this study was to evaluate the demographic, histologic, and topographic characteristics, and the association of synchronous and metachronous multiple primary neoplasms.
  18. pmc Morphological types of breast cancer in family members and multiple primary tumours: is morphology genetically determined?
    Kari Hemminki
    Department of Biosciences at Novum, Karolinska Institute, Huddinge, Sweden
    Breast Cancer Res 4:R7. 2002
    ..We conducted the present study to determine whether breast cancer morphology is genetically determined...
  19. ncbi Synchronous colorectal adenocarcinoma and gastrointestinal stromal tumor (GIST)
    Marcovalerio Melis
    Department of Surgery, University of Chicago Hospitals, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Int J Colorectal Dis 22:109-14. 2007
    ..We present two cases of an invasive colon cancer with a synchronous small-bowel GIST; immunohistochemistry studies were performed to evaluate possible genetic similarities...
  20. ncbi Women with multiple primary breast cancers diagnosed within a five year period, 1994-1998
    Holly L Howe
    North American Association of Central Cancer Registries, 2121 W White Oaks Dr, Springfield, IL, 62704 6495, USA
    Breast Cancer Res Treat 90:223-32. 2005
    ..The 1994-1998 NAACCR dataset aggregated from high quality registries representing more than one-third of the US population provides a unique opportunity to examine the incidence of multiple primary breast cancers in a large population...
  21. ncbi [Dual tumours in the GI tract: synchronous and metachronous stromal (GIST) and epithelial/neuroendocrine neoplasms]
    Erika Kövér
    Baranya Megyei Kórház, Pecs 7623, Hungary
    Magy Onkol 48:315-21. 2004
    ....
  22. ncbi Simultaneously detected endometrial and ovarian carcinomas--a prospective clinicopathologic study of 74 cases: a gynecologic oncology group study
    R Zaino
    Department of Pathology, Milton S. Hershey Medical Center of Pennsylvania State University, Hershey, Pennsylvania 17033, USA
    Gynecol Oncol 83:355-62. 2001
    ....
  23. pmc Multicentricity of breast cancer: whole-organ analysis and clinical implications
    J S Vaidya
    Department of Surgical Oncology, Tata Memorial Hospital, Bombay, India
    Br J Cancer 74:820-4. 1996
    ..Our finding, that in half the patients (15/30) MCF are present in quadrants other than the index quadrant, suggests that MCF do not give rise to early breast recurrence...
  24. ncbi Prognostic significance of bladder tumor history and tumor location in upper tract transitional cell carcinoma
    Bulent Akdogan
    Department of Urology, Hacettepe University, School of Medicine, Ankara 06700, Turkey
    J Urol 176:48-52. 2006
    ..We studied prognostic factors for 5-year disease specific and recurrence-free survival in patients treated for upper urinary tract transitional cell carcinoma...
  25. ncbi Glutathione S-transferase M1 or T1 null genotype as a risk factor for developing multiple primary neoplasms in the upper aero-digestive tract, in Indian males using tobacco
    Sameer Jhavar
    Department of Radiation Oncology, Tata Memorial Hospital, Parel, Mumbai, India
    Oral Oncol 40:84-91. 2004
    ..Indian male tobacco users with upper aero-digestive tract (UADT) squamous carcinoma, 30 patients with multiple primary neoplasms (MPN) were compared with 28 age and sex matched patients with a single primary neoplasm (SPN) for ..
  26. ncbi Microsatellite instability of cancers and concomitant adenomas in synchronous multiple colorectal cancer patients
    E Ueda
    Dept of Surgical Oncology, Graduate School of Medicine, The University of Tokyo, Japan
    J Exp Clin Cancer Res 21:149-54. 2002
    ....
  27. ncbi Simultaneous laparoscopic management of 3 urological malignancies
    Donna Y Deng
    Department of Urology, University of California School of Medicine, San Francisco, California, USA
    J Urol 167:2125-6. 2002
  28. ncbi Multiple primary tumours of the parotid gland
    G Y Yu
    Center for Salivary Gland Diseases, Peking University School of Stomatology, Beijing 100081, China
    Int J Oral Maxillofac Surg 33:531-4. 2004
    ..B-mode ultrasound is the technique of choice for the screening of MPT. Meticulous intraoperative inspection and palpation of the glandular tissues and periglandular lymph nodes are necessary...
  29. ncbi A 10-year review of primary fallopian tube cancer at a community hospital: a high association of synchronous and metachronous cancers
    M F Benoit
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Texas Medical Branch, 301 University Boulevard, Route 0587, Galveston, TX 77555, USA
    Int J Gynecol Cancer 16:29-35. 2006
    ..The median follow-up was 38 months. This report details the diagnostic and therapeutic experience of patients with PFTC and describes the occurrence of synchronous and metachronous gynecological cancers...
  30. ncbi On the origin of syn- and metachronous urothelial carcinomas
    Mattias Hoglund
    Department of Clinical Genetics, Lund University Hospital, Lund SE 221 85, Sweden
    Eur Urol 51:1185-93; discussion 1193. 2007
    ..To evaluate existing models for the origin of meta- and synchronous urothelial carcinomas in light of the accumulated genetic data...
  31. ncbi Multifocal, multicentric, and contralateral breast cancers: bilateral whole-breast US in the preoperative evaluation of patients
    Woo Kyung Moon
    Department of Radiology, Clinical Research Institute, Seoul National University Hospital and the Institute of Radiation Medicine, Seoul National University Medical Research Center, 28 Yongon Dong, Chongno Gu, Seoul 110 744, Korea
    Radiology 224:569-76. 2002
    ..To evaluate the efficacy of preoperative bilateral whole-breast ultrasonography (US) in the detection of additional multifocal, multicentric, and contralateral cancers and the effect of US information on therapeutic decisions...
  32. ncbi [Synchronous diagnosis of small-cell lung cancer and Hodgkin lymphoma]
    A S Rubiales
    An Med Interna 23:301-2. 2006
  33. ncbi Clinical analysis of synchronous primary neoplasms of the female reproductive tract
    Seo Yun Tong
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The Catholic University of Korea, 505 Banpo Dong, Seocho Gu, Kangnam St Mary s Hospital, Seoul 137 040, Republic of Korea
    Eur J Obstet Gynecol Reprod Biol 136:78-82. 2008
    ..In this study, a histopathologic review of synchronous primary neoplasms including gynecologic malignancies is presented, and the possible correlation among discrete tumor subsets, natural history, and survival is evaluated...
  34. ncbi Breast cancer in an MSH2 gene mutation carrier
    Pieter J Westenend
    Laboratory for Pathology Dordrecht, 3317 NL Dordrecht, The Netherlands
    Hum Pathol 36:1322-6. 2005
    ..We tested the tumor for loss of heterozygosity of the MSH2 gene and found loss of the wild-type MSH2 allele. These data strongly suggest that the MSH2 gene was involved in the development of this breast tumor...
  35. ncbi Synchronous benign and malignant salivary gland tumors in ipsilateral glands: a report of two cases and a review of literature
    Jonathan L Curry
    Department of Pathology, Loyola University Medical Center, Loyola University Medical Center, 2160 S First Avenue, Maywood, Illinois 60153, USA
    Head Neck 24:301-6. 2002
    ..3% of all salivary gland neoplasms. Only nine cases of synchronous benign and malignant ipsilateral parotid gland tumors have been described in the literature...
  36. pmc Cystadenocarcinoma of the appendix: an incidental imaging finding in a patient with adenocarcinomas of the ascending and the sigmoid colon
    Michail Pitiakoudis
    2nd Department of Surgery, Medical School, Democritus University of Thrace, Alexandroupolis
    BMC Gastroenterol 3:30. 2003
    ..Primary adenocarcinomas of the appendix are uncommon. Mucoceles that result from mucinous adenocarcinomas of the appendix may be incidentally detected on imaging...
  37. ncbi Prognostic significance of synchronous and metachronous bilateral breast cancer
    J Kollias
    Professorial Unit of Surgery, City Hospital, Hucknall Road, Nottingham NG5 1PB, UK
    World J Surg 25:1117-24. 2001
    ..However, the time duration to metachronous contralateral breast cancer did not have prognostic significance in a multivariate model compared with the prognostic features of the original primary...
  38. ncbi Familial bilateral acinic cell carcinoma of the parotid synchronous with pituitary adenoma: case report
    Alexander Delides
    Department of Otolaryngology, Athens Medical Center, Distomou 5 7, Marousi, 151 25 Athens, Greece
    Head Neck 27:825-8. 2005
    ..Acinic cell carcinoma is a common neoplasm of the salivary glands that occurs predominately in the parotid. Only one case of a familial recurrence of such a neoplasm and 16 cases of bilateral tumors have been reported...
  39. pmc Incidence of multiple primary cancers in a cohort of women diagnosed with breast cancer in southeast England
    H S Evans
    Thames Cancer Registry, Division of Oncology, Guy s, King s and St Thomas School of Medicine, Kings College, London, UK
    Br J Cancer 84:435-40. 2001
    ..Some of these associations are consistent with the effects of known inherited cancer susceptibility genes, shared environmental factors, or therapy...
  40. ncbi Risk factors for synchronous primary endometrial and ovarian cancers
    L J Herrinton
    Division of Research, Kaiser Permanente, Oakland, CA 94611, USA
    Ann Epidemiol 11:529-33. 2001
    ..CONCLUSIONS: Though limited by relatively small numbers, our results suggest that the presence of some common etiologies is a basis for the unusually high co-occurrence of endometrial and ovarian cancers...
  41. ncbi Multiple synchronous and metachronous neoplasms of the parotid gland: the Chichester experience
    M Ethunandan
    Maxillofacial Unit, St Richard s Hospital, Chichester, West Sussex, UK
    Br J Oral Maxillofac Surg 44:397-401. 2006
    ..Ipsilateral tumours of differing histological types and identical tumours other than Wartin's were uncommon. All but one patient had superficial parotidectomies and there were no recurrences...
  42. ncbi Profile of women 45 years of age and younger with endometrial cancer
    E R Evans-Metcalf
    Department of Obstetrics and Gynecology, University of Massachusetts Medical Center, Worcester 01655, USA
    Obstet Gynecol 91:349-54. 1998
    ..The clinical characteristics and outcomes of endometrial cancer patients 45 years of age and younger were compared with those of patients older than 45 years of age...
  43. ncbi Four percent of patients undergoing colorectal cancer surgery may have synchronous appendiceal neoplasia
    Muhammad Najm Khan
    Department of Colorectal Surgery, North Hampshire Hospital NHS Trust, Basingstoke, RG24 9NA, United Kingdom
    Dis Colon Rectum 50:1856-9. 2007
    ..A special interest of the senior author in appendiceal and rectal cancer has prompted routine removal of the appendix in all cases undergoing surgery for colorectal cancer...
  44. ncbi Synchronous primary adenocarcinoma and gastrointestinal stromal tumor in the stomach: a report of two cases
    Sema Bircan
    Department of Pathology, School of Medicine, Suleyman Demirel University, Isparta, Turkey
    Turk J Gastroenterol 15:187-91. 2004
    ..In this article, we report two cases of synchronous development of stromal tumor and adenocarcinoma incidentally detected in the stomach in two elderly patients...
  45. pmc Germline truncating mutations in both MSH2 and BRCA2 in a single kindred
    I Thiffault
    Program in Cancer Genetics, Department of Oncology and Human Genetics, McGill University, Montreal, Quebec, Canada
    Br J Cancer 90:483-91. 2004
    ..Additionally, two double heterozygotes did not appear to have a different phenotype than would be expected from the presence of a mutation in each gene alone...
  46. ncbi Fine-needle aspiration cytology of splenic hamartoma
    Sheng Huang Lee
    Department of Pathology, Taipei Municipal Ho Ping Hospital, Taipei, Taiwan
    Diagn Cytopathol 28:82-5. 2003
    ..A combination of cytologic features and immunopathologic results from the aspirate cytoblock along with the salient clinical information should enable an accurate preoperative diagnosis of splenic hamartoma...
  47. ncbi Risk of second cancer among women with breast cancer
    Lene Mellemkjaer
    Institute of Cancer Epidemiology, Danish Cancer Society, Copenhagen, Denmark
    Int J Cancer 118:2285-92. 2006
    ....
  48. ncbi Acute cholecystitis as a presentation of metastatic breast carcinoma of the gallbladder: a case report
    Benedetta Boari
    J Am Geriatr Soc 53:2041-3. 2005
  49. ncbi BRAF as a melanoma susceptibility candidate gene?
    Karine Laud
    Service de Genetique, Institut Gustave Roussy, 94800 Villejuif, Cedex, France
    Cancer Res 63:3061-5. 2003
    ..Moreover, there was no significant difference in the frequency of heterozygotes for BRAF variants between melanoma cases and controls when they were compared. Our data suggest that BRAF is unlikely to be a melanoma susceptibility gene...
  50. ncbi Occurrence of other malignancies in patients with gastrointestinal stromal tumors
    Abbas Agaimy
    Institute of Pathology, Nuremberg Clinic Center, Nuremberg, Germany
    Semin Diagn Pathol 23:120-9. 2006
    ..The potential nonrandom association and causal relationship between GIST and other neoplasms remain to be investigated...
  51. pmc Importance of extensive staging in patients with mucosa-associated lymphoid tissue (MALT)-type lymphoma
    M Raderer
    Department of Internal Medicine I, University of Vienna, Austria
    Br J Cancer 83:454-7. 2000
    ..In addition, our data suggest that extra-gastrointestinal MALT-type lymphoma more frequently occurs simultaneously at different anatomic sites than MALT-type lymphoma involving the GI-tract...
  52. ncbi "Seedling" mesenchymal tumors (gastrointestinal stromal tumors and leiomyomas) are common incidental tumors of the esophagogastric junction
    Susan C Abraham
    Division of Anatomic Pathology, Department of Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 31:1629-35. 2007
    ..The common occurrence of microscopic GISTs compared with the rarity of clinically manifest and malignant esophagogastric GISTs suggests that additional genetic or epigenetic alterations must happen for neoplastic progression...
  53. ncbi Gastrointestinal stromal tumours in a single institute: is there an association to other gastrointestinal malignancies?
    Katalin Kalmar
    Department of Surgery, University of Pecs, Hungary
    Magy Seb 57:251-6. 2004
    ..05). Significantly more synchronous or metachronous gastrointestinal malignancies were found is this population of GIST patients, when compared to the prevalence of malignancies in normal Hungarian population (p<0.001)...
  54. ncbi Ganglioneuromatous polyposis associated with juvenile polyps and a tubular adenoma
    Shazia Rafiq
    Department of Pathology, State University of New York at Buffalo, VA Western New York Healthcare System, Buffalo, New York 14215, USA
    Dig Dis Sci 50:506-8. 2005
  55. ncbi Hybrid carcinomas of the salivary glands: report of nine cases with a clinicopathologic, immunohistochemical, and p53 gene alteration analysis
    Toshitaka Nagao
    Department of Surgical Pathology, Tokyo Medical University Hospital, Tokyo, Japan
    Mod Pathol 15:724-33. 2002
    ..Therefore, there is the possibility that such molecular-genetic events take an integral part for inducing the transformation from histologically lower to higher grade tumor during the hybrid carcinoma genesis of the salivary glands...
  56. ncbi Breast plasmacytoma
    O Lamy
    Service de Medecine Interne A, Department of Internal Medicine, University Hospital, Lausanne, Switzerland
    Leuk Lymphoma 37:611-5. 2000
    ..Breast plasmacytoma is exceedingly rare. We identified 37 cases published between 1928 and 1999, and reviewed the clinical features of this unusual presentation of plasmacytoma...
  57. ncbi Hepatoid malignancy of unknown origin--a diagnostic conundrum: review of literature and case report of collision with adenocarcinoma
    Raja Gopaldas
    Department of Surgery, Easton Hospital, 250 South 21st Street, Easton, PA 18042, USA
    Surg Oncol 14:11-25. 2005
    ....
  58. pmc Familial/bilateral and sporadic testicular germ cell tumors show frequent genetic changes at loci with suggestive linkage evidence
    R I Skotheim
    Department of Genetics, Institute for Cancer Research, The Norwegian Radium Hospital, Montebello, Oslo N-0310, Norway
    Neoplasia 3:196-203. 2001
    ....
  59. ncbi Synchronous primary adenocarcinoma, mucosa-associated lymphoid tissue lymphoma and a stromal tumor in a Helicobacter pylori-infected stomach
    Arthur Kaffes
    Department of Gastroenterology, The University of Sydney, Concord Hospital, New South Wales, Australia
    J Gastroenterol Hepatol 17:1033-6. 2002
    ..Gastrointestinal stromal cell tumors have not been associated with infection to date. This appears to be the first report of the synchronous occurrence of these three gastric tumors...
  60. ncbi Clinical characteristics of metachronous bilateral testicular tumors in the chemotherapeutic era
    D S Park
    Department of Urology, Pundang CHA Hospital, Pochon CHA University, Sungnam, Korea
    Yonsei Med J 40:137-43. 1999
    ..Close follow-up of the contralateral testis with ultrasonography is essential for early detection of second tumors. The outcome for patients with bilateral testicular germ cell cancer is excellent, secondary to early detection...
  61. ncbi Defective mismatch-repair in patients with multiple primary tumours including colorectal cancer
    K Ericson
    Department of Oncology, University Hospital, 221 85 Lund, Sweden
    Eur J Cancer 39:240-8. 2003
    ..We conclude that the development of multiple primary tumours, including synchronous or metachronous colorectal cancers, is associated with an increased frequency of MSI and loss of immunohistochemical expression of MLH1 and MSH2...
  62. ncbi The CDKN2A tumour suppressor gene: no mutations detected in patients with melanoma and additional unrelated cancers
    J P Alao
    Catherine Griffiths Cancer Research Laboratory, Melanoma Unit, Hammersmith Hospitals NHS Trust, Charing Cross Hospital, London, UK
    Melanoma Res 12:559-63. 2002
    ..However, it would appear that melanoma and additional, apparently unrelated, cancers developing in the same individual are likely to be related to a combination of low-risk susceptibility genes and environmental factors...
  63. ncbi [Synchronous chromophobe renal carcinoma and centrocytic lymphoma]
    Antonio Javier Márquez Moreno
    Servicios de Radiodiagnóstico, Hospital Clinico Universitario, Malaga, Espana
    Arch Esp Urol 56:415-7. 2003
    ....
  64. ncbi [Multiple primary cancers with different localizations and histologic types. Clinical case]
    Emilia Tabacu
    Institutul de Pneumologie Marius Nasta, Bucuresti
    Pneumologia 52:51-3. 2003
    ..For both cerebral and renal tumors the patient was given a surgical treatment and for the Hodgkin's disease and lung cancer given chemotherapy and cobalt therapy...
  65. ncbi Intercalated duct hyperplasia: possible relationship to epithelial-myoepithelial carcinoma and hybrid tumours of salivary gland
    R Chetty
    Division of Anatomical Pathology, University of Natal School of Pathology and Laboratory Medicine, Durban, South Africa
    Histopathology 37:260-3. 2000
    ....
  66. ncbi [Surgical treatment and prognosis of synchronous double primary lung cancer: a report of 31 cases]
    Fei Yue Feng
    Department of Thoracic Surgery, Cancer Hospital Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, P R China
    Ai Zheng 24:215-8. 2005
    ..This study was to investigate effective surgical treatment, and prognosis of synchronous DPLC...
  67. ncbi Treatment of double carcinoma of the esophagus and lung
    Hiromichi Ishii
    Division of Esophageal Surgery, Shizuoka Cancer Center, Shimonagakubo 1007, Nagaizumichou, Sunto gun, Shizuoka, 411 8777, Japan
    Gen Thorac Cardiovasc Surg 56:126-30. 2008
    ..A two-stage operation is considered a suitably safe surgical procedure because no fatal postoperative complications occurred in cases 3 and 4...
  68. ncbi Tumor-to-tumor metastasis: report of 2 cases of metastatic carcinoma to angiomyolipoma of the kidney
    Reva Ricketts
    Department of Pathology, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Arch Pathol Lab Med 132:1016-20. 2008
    ..An awareness of this phenomenon is important to avoid an incorrect diagnosis when encountering unusual morphologic features in renal angiomyolipoma...
  69. ncbi Chronic arsenic poisoning: a global health issue -- a report of multiple primary cancers
    R R Walvekar
    Department of Head and Neck Surgery, Tata Memorial Hospital, Parel, Mumbai, India
    J Cutan Pathol 34:203-6. 2007
    ..A case presenting with multiple cutaneous cancers as well as an internal lung primary in a patient exposed to toxic levels of As in the drinking water is discussed along with a review of literature...
  70. ncbi [Loss of differentiation of a prostate adenocarcinoma after hormone therapy: the example of a metastasis in the spongy body of the penis]
    J Uphoff
    Klinik für Urologie und Kinderurologie, Ammerland Klinik GmbH, Westerstede
    Aktuelle Urol 39:373-7. 2008
    ..The increasing histological dedifferentiation of the tumour tissue can make it difficult or even impossible to identify the primary lesion...
  71. ncbi Metachronous and synchronous lung tumors: five malignant lung pathologies in 1 patient during 7 years
    Michael J Flynn
    Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle on Tyne, Newcastle on Tyne, United Kingdom
    Ann Thorac Surg 78:2154-5. 2004
    ..This case demonstrates the importance of screening after the diagnosis and treatment of lung carcinoma...
  72. ncbi [Synchronous double carcinoma of the left lung and esophagus; report of a case]
    M Takeo
    Department of Surgery, Kobe City Medical Center West Hospital, Kobe, Japan
    Kyobu Geka 61:808-11. 2008
    ..Pathological diagnosis was moderately differentiated squamous cell carcinoma of the esophagus and well differentiated adenocarcinoma of the lung. Synchronous double carcinoma of the lung and the esophagus is rare...
  73. ncbi Pathologic quiz case: unusual morphology in an otherwise classic renal cell carcinoma. Tumor-to-tumor metastasis: pulmonary adenocarcinoma metastatic to clear cell renal cell carcinoma
    Laura A Granville
    Department of Pathology, The Methodist Hospital and Baylor College of Medicine, Houston, TX, USA
    Arch Pathol Lab Med 129:e49-50. 2005
  74. ncbi Synchronous esophageal and renal cell carcinoma: incidence and possible treatment strategies
    I H J T de Hingh
    Department of Surgery, Academic Medical Center at the University of Amsterdam, Amsterdam, The Netherlands
    Dig Surg 25:27-31. 2008
    ..The present study investigated the incidence of synchronously detected RCC since the introduction of preoperative CT scans in a tertiary referral center for esophageal cancer patients...
  75. ncbi [Lung cancer at a university hospital: epidemiological and histological characteristics of a recent and a historical series]
    M J Santos-Martinez
    Servei de Pneumologia, Hospital del Mar, Universitat Autonoma de Barcelona, Barcelona, Spain
    Arch Bronconeumol 41:307-12. 2005
    ..To describe the clinical, histological, and epidemiological characteristics of patients diagnosed with lung cancer in our hospital over a period of 5 years and compare them with those of historical cases treated at the same hospital...
  76. ncbi [Synchronous renal clear-cell carcinoma and ipsilateral transitional-cell carcinoma: case report and bibliographic review]
    Manuel Fernández Arjona
    Servicio de Urologia, Hospital Santa Barbara, Puertollano, Ciudad Real, Espana
    Arch Esp Urol 58:460-3. 2005
    ..We report a new case of simultaneous renal cell adenocarcinoma and ipsilateral multifocal transitional cell carcinoma...
  77. ncbi Synchronous multiple primary lung cancers with different response to gefitinib
    Baek Yeol Ryoo
    Department of Internal Medicine, Korea Cancer Center Hospital, 215 4, Gongneung dong, Nowon Gu, Seoul, 139 706, Republic of Korea
    Lung Cancer 53:245-8. 2006
    ..These synchronous tumors with different location, histology, status of EGFR-TK mutations and response to chemotherapy might be caused by different molecular pathogenesis...
  78. ncbi [Pleomorphic carcinoma of the lung rapidly developed multiple metastases after surgery]
    M Segawa
    Department of Thoracic and Vascular Surgery, Toyama City Hospital, Toyama, Japan
    Kyobu Geka 59:387-91. 2006
    ..He died of peritonitis and pleuritis on only 60 days after the operation...
  79. ncbi Recurrent endometrial cancer: patterns of recurrent disease and assessment of prognosis
    S A Sohaib
    Department of Radiology, Royal Marsden Hospital, London, UK
    Clin Radiol 62:28-34; discussion 35-6. 2007
    ..To evaluate patterns of disease and identify factors predicting outcome in patients presenting with recurrent endometrial adenocarcinoma following primary surgery...
  80. ncbi [Synchronous primary lung cancers: due to the four cases]
    Irfan Ucgun
    Pulmonary Diseases, Faculty of Medicine, Osmangazi University, Eskisehir, Turkey
    Tuberk Toraks 52:262-7. 2004
    ..Due to the this report, we emphasized that diagnostic procedures should be done separately for each lesions in patients who had more than one lesion, and treatment should plane according to these results...
  81. ncbi Consecutive left lower sleeve lobectomy and left S3 segmentectomy for a patient with node-negative double lung cancer
    Satoshi Yamamoto
    Second Department of Surgery, Fukuoka University School of Medicine, Japan
    Jpn J Thorac Cardiovasc Surg 54:342-4. 2006
    ..He was discharged uneventfully on the 14th day after the operation, and he has since been doing fine without lung caner recurrence for 3 years after surgery...
  82. ncbi [Frequency and distribution pattern of distant metastases in patients with ENT tumors and their consequences for pretherapeutic staging]
    Barbara Dietl
    Klinik und Poliklinik für Strahlentherapie, Universitat Regensburg, Regensburg, Deutschland
    Strahlenther Onkol 183:138-43. 2007
    ..influenced the frequency of distant metastases in patients with locally advanced ear-nose-throat (ENT) tumors, which was the distribution pattern of metastases, and what were the diagnostic consequences for pretherapeutic staging?..
  83. ncbi Synchronous small-cell lung cancer following colorectal carcinoma. An uncommon entity in the elderly
    M Escalante
    Rev Esp Enferm Dig 99:119-20. 2007
  84. ncbi Synchronous metastatic malignant melanoma and primary adenocarcinoma in the colon
    Hsin Hui Chiu
    Division of Gastroenterology, Department of Medicine and Pathology, Kuo General Hospital, Tainan, Taiwan
    Gastrointest Endosc 66:600; discussion 601. 2007
  85. ncbi [Correlation of multiple primary lung cancer with bronchial and alveolar epithelial dysplasia]
    Guo Feng Wang
    Department of Pathology, The Second Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou 310009, China
    Zhejiang Da Xue Xue Bao Yi Xue Ban 34:427-31. 2005
    ..To investigate the correlation of multiple primary lung cancer with bronchial epithelial dysplasia and atypical adenomatous hyperplasia of bronchiolo-alveolar epithelium...
  86. ncbi Florid cutaneous papillomatosis with acanthosis nigricans in a patient with carcinomas of the lung and prostate
    Wolfgang Weger
    J Am Acad Dermatol 57:907-8. 2007
  87. ncbi A rational approach to pulmonary screening in newly diagnosed head and neck cancer
    Kwok Seng Loh
    Department of Otolaryngology, University Health Network, Wharton Head and Neck Center, Princess Margaret Hospital, 610 University Avenue Canada 3 952, Toronto, Ontario M5G 2M9, Canada
    Head Neck 27:990-4. 2005
    ....
  88. ncbi Small cell carcinoma of the prostate. A morphologic and immunohistochemical study of 95 cases
    Wenle Wang
    Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
    Am J Surg Pathol 32:65-71. 2008
    ..P501S and prostate-specific membrane antigen were better in identifying the prostatic origin of small cell carcinoma than PSA, although the majority (60%) of prostatic small cell carcinomas were negative for all 3 markers...
  89. ncbi [Adrenal metastasis of lung adenocarcinoma with unusual sites of lymph node metastasis and concomitant renal cell carcinoma: a case report]
    Hideo Otsuki
    Department of Urology, National Defense Medical College
    Hinyokika Kiyo 53:879-82. 2007
    ..According to pathological findings and an elevation of carcinoembryogenic antigen, the adrenal lesion was diagnosed as adrenal metastasis of lung adenocarcinoma...
  90. ncbi Acute interstitial pneumonia following surgery for primary lung cancer
    Masashi Muraoka
    Division of Surgical Oncology, Department of Translational Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
    Eur J Cardiothorac Surg 30:657-62. 2006
    ..We conducted this study to determine the characteristics of acute interstitial pneumonia after pulmonary resection and to identify the risk factors for this disease...
  91. ncbi Radiology-Pathology Conference: Bilateral renal oncocytomas
    Lewis K Shin
    Department of Radiology, Winthrop University Hospital, 259 First Street, Mineola, NY 11501, USA
    Clin Imaging 28:344-8. 2004
    ..Accurate preoperative diagnosis and differentiation from renal carcinoma is difficult. We report the radiology and pathology of a patient with bilateral renal oncocytomas and review the literature of this rare presentation...
  92. ncbi [Sugar tumor of the lung--case report and review of the literature]
    V Fackeldey
    Abteilung für Allgemein, Viszeral und Thoraxchirurgie, Bundeswehrzentralkrankenhaus Koblenz
    Chirurg 74:683-6. 2003
    ..We present a case of metachronic, benign, and HMB-45-negative sugar tumor of the lung after hypernephroma and give a review of the literature...
  93. ncbi [A resected case of multiple lung cancers]
    M Kitada
    Department of Chest Surgery, Obihiro National Sanatorium, Obihiro, Japan
    Kyobu Geka 54:345-8. 2001
    ..Histological examination confirmed well-differentiated squamous cell carcinoma from the S10 and well-differentiated adenocarcinoma from the S2. He is healthy three year after operation...
  94. ncbi [A case of collision tumor involving the mouth of the left lower lobe bronchus treated by left lower sleeve lobectomy]
    K Yamamoto
    Department of Respiratory Disease, Matsue Red Cross Hospital, Shimane, Japan
    Kyobu Geka 54:513-6. 2001
    ..We performed left sleeve lower lobectomy and the postoperative pathologic examination revealed a collision tumor comprising adenocarcinoma and squamous cell carcinoma...
  95. ncbi [A case of triple malignancies (gastric cancer, lung cancer and malignant pleural mesothelioma) after asbestos exposure]
    Takumi Kishimoto
    Department of Laborer s Respiratory Diseases, Okayama Rousai Hospital, Okayama, Japan
    Nihon Kokyuki Gakkai Zasshi 41:304-9. 2003
    ..It is well known that lung cancer and malignant mesothelioma are induced by asbestos exposure, but multiple cancers including lung cancer and malignant mesothelioma are extremely rare...
  96. ncbi [Cavitary pulmonary metastasis from bladder cancer: a case report]
    Akira Yamasaki
    Third Department of Internal Medicine, Faculty of Medicine, Tottori University, 36 1 Nishi machi, Yonagoshi, Tottori Pref
    Nihon Kokyuki Gakkai Zasshi 41:95-8. 2003
    ..Cavitating pulmonary metastasis is uncommon. We report a rare case of pulmonary metastasis from bladder cancer, with mixed-type histopathology at both primary and metastatic sites...
  97. ncbi Utility of chest computed tomography for staging in patients with T1 extremity soft tissue sarcomas
    J B Fleming
    Sarcoma Center, The University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030-4009, USA
    Cancer 92:863-8. 2001
    ..The findings of the current study do not support current NCCN or SSO practice guidelines for patients with high-grade T1 STS...
  98. ncbi Molecular analysis of synchronous and metachronous tumors of the lung: impact on management and prognosis
    J Huang
    Department of Pathology, Bellevue-New York University Medical Center, New York, NY, USA
    Ann Diagn Pathol 5:321-9. 2001
    ..Our data suggest that molecular analysis can help fingerprint tumors and has the potential to significantly impact management and prognosis of patients...
  99. ncbi Familial papillary renal cell tumors and subsequent cancers: a nationwide epidemiological study from Sweden
    Kamila Czene
    Department of Biosciences at Novum, Karolinska Institute, Huddinge, Sweden
    J Urol 169:1271-5. 2003
    ..Familial risks in papillary renal cell carcinoma and association with second primary malignancies were studied using the nationwide Swedish Family Cancer Data Base...
  100. ncbi Philadelphia chromosome-positive chronic myeloid leukemia expressing p190(BCR-ABL)
    Akimichi Ohsaka
    Department of Transfusion Medicine, Juntendo University School of Medicine, Tokyo
    Intern Med 41:1183-7. 2002
    ....
  101. ncbi [Surgery for multiple primary lung cancers]
    Y Yamakawa
    Department of Surgery II, Nagoya City University Medical School, Nagoya, Japan
    Kyobu Geka 55:10-4. 2002
    ..Their 5 year survival rate was 36%. Especially of the patients with stage I lung cancer, 5 year survival rate was 65%. Radical but less invasive operation like VATS should be chosen for their treatment...

Research Grants35

  1. FAMILIAL COLORECTAL NEOPLASIA COLLABORATIVE GROUP
    Noralane Lindor; Fiscal Year: 2007
    ..fs20\par \par } ..
  2. CLINICAL AND GENETIC ANALYSIS OF SCHWANNOMATOSIS
    Mia MacCollin; Fiscal Year: 2001
    ....
  3. Consortium for the Molecular and Cell Biology of NF
    Mia MacCollin; Fiscal Year: 2004
    ....
  4. HIV and the Proteasome in the Aging Human Brain
    Benjamin Gelman; Fiscal Year: 2005
    ..The linkage between brain inflammation and altered neuronal protein turnover could lead to a unifying functional concept of dementia with application to HIV and aging both. ..
  5. Genotype Phenotype Relationship in Neurofibromatosis 2
    Mia MacCollin; Fiscal Year: 2005
    ..Finally, the determination of genotype-phenotype relationships will aid in the prognostication and effective management of this devastating disorder. ..
  6. Depo-Provera and Breast Cancer: Epidemiology/Pathology
    Christopher Li; Fiscal Year: 2009
    ..such as parity and body mass index, modify this association?;and (3) Does the association between DMPA and breast cancer risk vary by histologic type or by the expression of steroid receptors including ERq, ERft, and PR? ..
  7. Characterization of the Chromosome 17q23 Amplicon
    Fergus Couch; Fiscal Year: 2006
    ..Thus, the project may involve a complete transition from benchtop to bedside. Finally, the amplified and overexpressed genes may prove useful as important targets of gene, pharmacological, and immunological therapy in the future. ..
  8. Mutational Analysis of Clonality in Multiple Primary Melanoma
    Irene Orlow; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  9. Mathematical Models of Programmed CTL Proliferation
    Dominik Wodarz; Fiscal Year: 2009
    ..These are the role of effector molecules (such as perform and IFN-g) for CTL dynamics, and the role of CD4 T cell help. The modeling work will be complemented by experiments with VSV and LCMV infected mice. ..
  10. Dopamine Systems and Neuropsychiatric Changes in HIV/AIDS
    Benjamin B Gelman; Fiscal Year: 2010
    ..The project breaks ground neuroscientifically, as no autopsy study has advanced to a "task specific" behavioral correlation with circuit level anomalies of a specific neurotransmitter system. ..
  11. Solar Exposure and Melanoma Survival
    Marianne Berwick; Fiscal Year: 2009
    ..2. Determine whether functional polymorphic variants in the vitamin D receptor affect survival from melanoma. 3. Investigate the interaction of lifetime solar exposure and polymorphisms in VDR and its effect on survival. ..
  12. Sphingolipid signaling in olfactory mucosa
    Mary Beth Genter; Fiscal Year: 2004
    ..abstract_text> ..
  13. MYELOPATHY AND NEUROPATHY DURING CHANGING HIV BURDEN
    Benjamin Gelman; Fiscal Year: 2004
    ..Together, the studies we have proposed will provide insights concerning prevalent AIDS morbidities in the HAART era. ..
  14. MECHANISMS OF BIOENGINEERED SKIN IN HUMAN WOUNDS
    Vincent Falanga; Fiscal Year: 2003
    ..The proposed studies will advance our understanding of how a bioengineered skin product works in a human chronic wound and provide insight into further bioengineering needs. ..
  15. Extracellular matrix in chloracetanilide carcinogenesis
    Mary Beth Genter; Fiscal Year: 2004
    ..abstract_text> ..
  16. A Pilot Writing Program for Multiethnic Breast Cancer Pt
    Carolyn Gotay; Fiscal Year: 2004
    ..This study will provide an initial step toward achieving this goal. ..
  17. MECHANISM OF INDUCTION OF OLFACTORY TUMORS BY ALACHLOR
    Mary Beth Genter; Fiscal Year: 2002
    ....
  18. AUTOCRINE ROLE OF GASTRIN-LIKE PEPTIDES IN COLON CANCER
    Pomila Singh; Fiscal Year: 2002
    ..If we are successful in purifying the novel GP-R (and confirm its role in mediating the mitogenic effects of gastrins) then one can develop systemic strategies to block the receptor mediated effects in future funding periods. ..
  19. PHENOTYPIC AND PSYCHOSOCIAL STUDY OF THE L1307K MUTATION
    Henry Lynch; Fiscal Year: 2004
    ....
  20. Protein Biomarkers of Cancer Risk in Older Persons
    Christopher Li; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  21. Hepatic Arterial Flouridine and IV Bevacizumab for Primary Hepatic Malignancy
    William Jarnagin; Fiscal Year: 2008
    ..Furthermore, several important clinical issues are addressed by the proposed correlative studies, the results of which would be of broad general interest in clinical oncology. [unreadable] [unreadable] [unreadable]..
  22. THE ROLE OF RB IN THE RETINA & OTHER TISSUES
    JAMES HARBOUR; Fiscal Year: 2009
    ..Consequently, these aims are highly relevant to the vision statement of the NEI, and they address several major program goals and objectives of the Retinal Diseases Program. ..
  23. P21 INDUCTION BY BRCA2
    Fergus Couch; Fiscal Year: 2002
    ....
  24. Growth Factors, Curcumin and Colon Carcinogenesis
    Pomila Singh; Fiscal Year: 2010
    ..The results of these studies are expected to help in developing mechanism-based strategies for preventative/treatment protocols for CRCusing curcumin like agents. ..
  25. IGFS & IGF-BINDING PROTEINS IN GROWTH & DIFFERENTIATION
    Pomila Singh; Fiscal Year: 2002
    ....
  26. Computer Aided Liver Lesion Detection Algorithm
    Lawrence Schwartz; Fiscal Year: 2005
    ..Clearly this is the first step in a process of development and if successful will lead to further efforts in automated detection and characterization. ..
  27. c-erbB-2 and Risk of Contralateral Breast Cancer
    Christopher Li; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  28. TEXAS REPOSITORY FOR AIDS NEUROPATHOGENESIS RESEARCH
    Benjamin Gelman; Fiscal Year: 2007
    ..abstract_text> ..
  29. Tissue Engineering for the Treatment of Delayed Healing
    Vincent Falanga; Fiscal Year: 2007
    ..These studies will advance our understanding of how to reconstitute the wound bed and whether it is possible to correct the abnormal cellular phenotype in non-healing wounds. ..
  30. Identification and characterization of the DFNB17 gene
    John Greinwald; Fiscal Year: 2006
    ....
  31. CAM Use in Asians & Pacific Islanders
    Carolyn Gotay; Fiscal Year: 2006
    ..abstract_text> ..
  32. The Risk of Cancer in Fanconi Anemia Heterozygotes
    Marianne Berwick; Fiscal Year: 2005
    ..Analyses will be undertaken to evaluate the role of Fanconi anemia heterozygosity for cancer. If carriers are found to be at increased risk, this information can be used to target individuals for cancer prevention strategies. ..
  33. PATHOGENIC MECHANISMS OF VENOUS DISEASE
    Vincent Falanga; Fiscal Year: 2004
    ..The proposed studies should advance knowledge of the pathogenesis of venous ulceration and fibrosis. ..
  34. Whole genome amplification and DNA pooling strategies
    Immaculata DeVivo; Fiscal Year: 2004
    ..Results from the pooling experiments will determine whether this method may be sensitive enough for use in nested case-control studies where a small difference in allele frequency is expected. ..
  35. Factors Influencing Use of Cancer Genetics by Physicians
    Marie Wood; Fiscal Year: 2004
    ....