eosinophilic granuloma

Summary

Summary: The most benign clinical form of Langerhans-cell histiocytosis (HISTIOCYTOSIS, LANGERHANS-CELL), which involves localized nodular lesions of the gastric mucosa, small intestine, bones, lungs, or skin, with infiltration by eosinophils. The proliferating cell that appears to be responsible for the clinical manifestations is the Langerhans cell.

Top Publications

  1. ncbi Eosinophilic granuloma of the orbit: understanding the paradox of aggressive destruction responsive to minimal intervention
    Kyung In Woo
    Section of Orbital and Ophthalmic Plastic Surgery, Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Ophthal Plast Reconstr Surg 19:429-39. 2003
  2. ncbi Langerhans cell histiocytosis of bone in children and adolescents
    Ismat Ghanem
    Children s Hospital Los Angeles, Los Angeles, California, USA
    J Pediatr Orthop 23:124-30. 2003
  3. ncbi [Eosinophilic granuloma of the temporal bone. Case report and literature review]
    M Hellmann
    Klinik für Hals Nasen Ohrenheilkunde, Kopf und Halschirurgie der Ruhr Universität Bochum am St Elisabeth Hospital Bochum
    Laryngorhinootologie 82:258-61. 2003
  4. ncbi Eosinophilic granuloma: resolution of maxillofacial bony lesions following minimal intervention. Report of three cases and a review of the literature
    Steven J Key
    Department of Maxillofacial Surgery, St Georges Hospital, Tooting, London, UK
    J Craniomaxillofac Surg 32:170-5. 2004
  5. ncbi Eosinophilic granuloma of the skull: a retrospective analysis
    Seong Hyun Park
    Department of Neurosurgery, Kyungpook National University Hospital, Daegu, South Korea
    Pediatr Neurosurg 43:97-101. 2007
  6. ncbi Birbeck granules or Birbeck junctions? Intercellular "zipperlike" lattice junctions in eosinophilic granuloma of bone
    I A Robb
    Division of Pathology, Children s Hospital of Eastern Ontario, Ottawa, Canada
    Ultrastruct Pathol 16:423-8. 1992
  7. ncbi Clinical and histological evaluation of an analogue of palmitoylethanolamide, PLR 120 (comicronized Palmidrol INN) in cats with eosinophilic granuloma and eosinophilic plaque: a pilot study
    F Scarampella
    Studio Dermatologico Veterinario, Via Sismondi 62, 20133 Milan, Italy
    Vet Dermatol 12:29-39. 2001
  8. ncbi Fasciola hepatica and parasitic eosinophilic granuloma of the Liver
    Jorge Vercelli-Retta
    Am J Surg Pathol 26:1238. 2002
  9. ncbi Eosinophilic granuloma in the jaws
    Maria Luiza dos Anjos Pontual
    Department of Clinic and Social Dentistry, School of Dentistry, Federal University of Paraiba, Joao Pessoa, Paraiba, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:e47-51. 2007
  10. ncbi Eosinophilic granuloma of the pediatric cervical spine
    Luca Denaro
    Department of Neurosurgery, Catholic University School of Medicine, Rome, Italy
    Spine (Phila Pa 1976) 33:E936-41. 2008

Research Grants

Detail Information

Publications205 found, 100 shown here

  1. ncbi Eosinophilic granuloma of the orbit: understanding the paradox of aggressive destruction responsive to minimal intervention
    Kyung In Woo
    Section of Orbital and Ophthalmic Plastic Surgery, Department of Ophthalmology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
    Ophthal Plast Reconstr Surg 19:429-39. 2003
    To describe the findings and outcomes in eosinophilic granuloma (unifocal Langerhans-cell histiocytosis [LCH]) of the orbit and to explain the paradox of aggressive bone destruction responsive to minimal intervention.
  2. ncbi Langerhans cell histiocytosis of bone in children and adolescents
    Ismat Ghanem
    Children s Hospital Los Angeles, Los Angeles, California, USA
    J Pediatr Orthop 23:124-30. 2003
    ..Lesions in group I and II patients had a considerable potential for spontaneous healing. Group III patients had the worst prognosis. Current chemotherapy protocols have a high morbidity and produce a variable response...
  3. ncbi [Eosinophilic granuloma of the temporal bone. Case report and literature review]
    M Hellmann
    Klinik für Hals Nasen Ohrenheilkunde, Kopf und Halschirurgie der Ruhr Universität Bochum am St Elisabeth Hospital Bochum
    Laryngorhinootologie 82:258-61. 2003
    b>Eosinophilic granuloma, Hand-Schüller-Christian disease an Letterer-Siwe disease are characterised by ideopathic proliferation of histiocytes producing focal or systemic manifestations...
  4. ncbi Eosinophilic granuloma: resolution of maxillofacial bony lesions following minimal intervention. Report of three cases and a review of the literature
    Steven J Key
    Department of Maxillofacial Surgery, St Georges Hospital, Tooting, London, UK
    J Craniomaxillofac Surg 32:170-5. 2004
    ..b>Eosinophilic granuloma accounts for 60-70% of all cases of Langerhans' cell histiocytosis and can present as solitary (50-75%) or ..
  5. ncbi Eosinophilic granuloma of the skull: a retrospective analysis
    Seong Hyun Park
    Department of Neurosurgery, Kyungpook National University Hospital, Daegu, South Korea
    Pediatr Neurosurg 43:97-101. 2007
    The authors describe 9 cases of children with eosinophilic granuloma (EG) of the skull and report on their clinical manifestations, treatment, and prognosis.
  6. ncbi Birbeck granules or Birbeck junctions? Intercellular "zipperlike" lattice junctions in eosinophilic granuloma of bone
    I A Robb
    Division of Pathology, Children s Hospital of Eastern Ontario, Ottawa, Canada
    Ultrastruct Pathol 16:423-8. 1992
    Three cases of eosinophilic granuloma of bone exhibited intercellular attachments between histiocytes, with a pentalaminar structure identical to that seen in nearby intracellular Birbeck granules (BG)...
  7. ncbi Clinical and histological evaluation of an analogue of palmitoylethanolamide, PLR 120 (comicronized Palmidrol INN) in cats with eosinophilic granuloma and eosinophilic plaque: a pilot study
    F Scarampella
    Studio Dermatologico Veterinario, Via Sismondi 62, 20133 Milan, Italy
    Vet Dermatol 12:29-39. 2001
    Fifteen cats with eosinophilic granuloma or eosinophilic plaque were given PLR 120 at the dosage of 10 mg kg-1 twice daily for one month. PLR-120 down-modulates mast cell degranulation via a receptor-mediated mechanism...
  8. ncbi Fasciola hepatica and parasitic eosinophilic granuloma of the Liver
    Jorge Vercelli-Retta
    Am J Surg Pathol 26:1238. 2002
  9. ncbi Eosinophilic granuloma in the jaws
    Maria Luiza dos Anjos Pontual
    Department of Clinic and Social Dentistry, School of Dentistry, Federal University of Paraiba, Joao Pessoa, Paraiba, Brazil
    Oral Surg Oral Med Oral Pathol Oral Radiol Endod 104:e47-51. 2007
    b>Eosinophilic granuloma is the most common expression of Langerhans cell histiocytosis and corresponds with typical bone lesions...
  10. ncbi Eosinophilic granuloma of the pediatric cervical spine
    Luca Denaro
    Department of Neurosurgery, Catholic University School of Medicine, Rome, Italy
    Spine (Phila Pa 1976) 33:E936-41. 2008
    Retrospective case review of children with eosinophilic granuloma of the cervical spine.
  11. ncbi Expression of matrix metalloproteinase-9 and significance of a macrophage assay in eosinophilic granuloma
    Manal Mohamed Zyada
    Faculty of Dentistry, Oral Pathology Department, Mansoura University, 35516 Mansoura, Egypt
    Ann Diagn Pathol 13:367-72. 2009
    Although most cases of eosinophilic granuloma (an immune-mediated lesion) do not behave in an aggressive manner, occasionally, recurrence after treatment has been observed...
  12. ncbi Eosinophilic granuloma manifesting as painless cervical lymphadenopathy in a patient positive for human immunodeficiency virus 1
    Peggy S Myung
    Department of Otorhinolaryngology Head and Neck Surgery, University of Pennsylvania Health System, Philadelphia, PA, USA
    Arch Otolaryngol Head Neck Surg 134:203-5. 2008
    b>Eosinophilic granuloma is rarely reported within lymph nodes. Furthermore, it is even more rarely reported in the setting of human immunodeficiency virus (HIV) infection...
  13. ncbi [Clinico-pathology of skull tumor: aneurysmal bone cyst, fibrous dysplasia, eosinophilic granuloma]
    Keiji Kawamoto
    Department of Neurosurgery, Kansai Medical University, 10 15 Fumizono cho, Moriguchi, Osaka 570 8506, Japan
    No Shinkei Geka 32:985-93. 2004
  14. ncbi An unusual presentation of eosinophilic granuloma in an adult: a case report
    B Garg
    Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India
    J Orthop Surg (Hong Kong) 14:81-3. 2006
    b>Eosinophilic granuloma is the most common and benign form of a rare proliferative disorder: Langerhans' cell histiocytosis. Spinal involvement is rare and only 15 adult cases have been reported...
  15. pmc Eosinophilic granuloma of the orbit: a paradox of aggressive destruction responsive to minimal intervention
    Gerald J Harris
    Section of Orbital and Ophthalmic Plastic Surgery, Department of Ophthalmology, Medical College Wisconsin, Milwaukee, USA
    Trans Am Ophthalmol Soc 101:93-103; discussion 103-5. 2003
    To describe the findings and outcomes in eosinophilic granuloma (unifocal Langerhans cell histiocytosis [LCH]) of the orbit, and to explain the paradox of aggressive bone destruction responsive to minimal intervention.
  16. ncbi Eosinophilic granuloma of the femur in an HIV-1-positive patient
    G D Panayiotakopoulos
    Department of Pathophysiology AIDS Unit, Laikon General Hospital and Medical School of Athens, Athens, Greece
    AIDS Patient Care STDS 16:103-6. 2002
    A case of eosinophilic granuloma in the right femur of an HIV-1-infected patient is described, and the possible pathogenetic role of HIV infection in eosinophilic granuloma formation is discussed.
  17. ncbi Eosinophilic granuloma arising from the pelvis in children: A report of three cases
    Akiro Ando
    Department of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan 980 8574
    Ups J Med Sci 113:209-16. 2008
    b>Eosinophilic granuloma (EG) is a benign tumor-like condition which is characterized by a clonal proliferation of Langerhans-type histiocytes and defined as a local form of Langerhans cell histiocytosis (LCH)...
  18. ncbi Simultaneous occurrence of Hodgkin's lymphoma and eosinophilic granuloma: a potential pitfall in positron emission tomography imaging
    Ralph Naumann
    Department of Internal Medicine I, University Hospital Carl Gustav Carus at the Dresden University of Technology, Dresden, Germany
    Clin Lymphoma 3:121-4. 2002
    ..This report deals with 2 patients with simultaneous occurrence of Hodgkin's lymphoma and eosinophilic granuloma, a rare but known coincidence of diseases...
  19. ncbi Eosinophilic granuloma. A different behaviour in children than in adults
    F Plasschaert
    Hospital for Sick Children and the Mount Sinai Hospital, Toronto, Canada
    J Bone Joint Surg Br 84:870-2. 2002
    Localised Langerhans-cell histiocytosis of bone (eosinophilic granuloma) is a benign tumour-like condition with a variable clinical course. Different forms of treatment have been reported to give satisfactory results...
  20. ncbi Surgical treatment of eosinophilic granuloma in the thoracic spine in patients with neurological lesions
    Eduardo Barros Puertas
    Department of Orthopedics and Traumatology, University Federal of São Paulo, Sao Paulo, Brazil
    J Pediatr Orthop B 12:303-6. 2003
    b>Eosinophilic granuloma is a benign, self-limited condition most commonly seen in children around 10 years of age. There is no known cause concerning its etiology...
  21. ncbi Solitary eosinophilic granuloma of sternum
    Atilla Eroglu
    Department of Thoracic Surgery, Ataturk University, Medical Faculty, Erzurum, Turkey
    Ann Thorac Surg 77:329-31. 2004
    ..Among those tumors, sternal tumors are rare and usually malignant. We report an extremely rare case of eosinophilic granuloma developed in the sternum in a 30-year-old woman...
  22. ncbi Solitary eosinophilic granuloma of the sternum
    Shigaku Sai
    Department of Orthopaedic Surgery, The Jikei University School of Medicine, 3 25 8 Nishi shinbashi, Minato ku, Tokyo, 105 8461, Japan
    J Orthop Sci 10:108-11. 2005
    We report a rare case of eosinophilic granuloma of the sternum in a 25-year-old woman, who presented with anterior chest pain and a tender mass over the sternum...
  23. ncbi Solitary eosinophilic granuloma of the radius. An unusual differential diagnosis
    Manish Chadha
    Department of Orthopaedics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Shahdara, Delhi, India
    Acta Orthop Belg 73:413-7. 2007
    ..Subsequently, a biopsy proved the lesion to be an eosinophilic granuloma of bone...
  24. ncbi Unusual location of eosinophilic granuloma
    Ammar S Haouimi
    Department of Radiology, Madina Maternity and Children s Hospital, Madina Al Munawara, Kingdom of Saudi Arabia
    Saudi Med J 25:1489-91. 2004
    b>Eosinophilic granuloma EG is a benign self-limiting disease, which belongs to the spectrum of Langerhans' cell histiocytosis LCH...
  25. ncbi Vertebral remodeling in eosinophilic granuloma of the spine. A long-term follow-up
    P Raab
    Department of Orthopaedic Surgery, , Germany
    Spine (Phila Pa 1976) 23:1351-4. 1998
    STUDY DESIGN: In this study, 14 conservatively treated patients were reviewed who had eosinophilic granuloma of the spine, which had been diagnosed on the basis of histologic study of the vertebral lesion or of specimens from other sites ..
  26. ncbi Eosinophilic granuloma of the liver: a characteristic lesion with relationship to visceral larva migrans
    K J Kaplan
    Department of Pathology, Walter Reed Army Medical Center, Washington, DC 20307 5001, USA
    Am J Surg Pathol 25:1316-21. 2001
    ..better the clinical, laboratory, and pathologic features of these lesions, we reviewed 43 cases of hepatic eosinophilic granuloma (excluding cases of Langerhans' cell histiocytosis) collected in the files of the AFIP over a period of 31 ..
  27. ncbi [Multifocal facial eosinophilic granuloma: successful treatment with topical tacrolimus]
    J Rieker
    Hautklinik der Heinrich Heine Universität, Dusseldorf
    Hautarzt 57:324-6. 2006
  28. ncbi Eosinophilic granuloma masquerading as aggressive periodontitis
    S S Silvestros
    Department of Prosthodontics, Dental School, University of Athens, Athens, Greece
    J Periodontol 77:917-21. 2006
    b>Eosinophilic granuloma (EG) is the mildest and mainly localized form of the clinicopathologic spectrum of Langerhans' cell histiocytosis. It is a destructive osseous lesion characterized by a vast number of eosinophils and histiocytes...
  29. ncbi Radiofrequency ablation of solitary eosinophilic granuloma of bone
    Rodney R Corby
    Department of Radiology, The University of Chicago Medical Center, MC 2026, 5841 S Maryland Ave, Chicago, IL 60637, USA
    AJR Am J Roentgenol 190:1492-4. 2008
    This article about our initial clinical experience describes the novel application of radiofrequency ablation for the treatment of two cases of solitary eosinophilic granuloma of the bone.
  30. ncbi Laser-assisted removal of a feline eosinophilic granuloma from the back of the tongue
    Katalin Kovacs
    Small Animal Veterinary Dental and Oral Surgery Clinic, Marek József utca 11 H 1078 Budapest, Hungary
    Acta Vet Hung 57:417-26. 2009
    ..The disease has three different manifestations: indolent cellular ulcer, eosinophilic plaque, and eosinophilic granuloma. The last mentioned form predominantly affects the medial surface of the thigh, the cheek, the tongue and ..
  31. ncbi Eosinophil-rich CD30+ lymphoproliferative disorder of the oral mucosa. A form of "traumatic eosinophilic granuloma"
    Bachir Alobeid
    Department of Pathology, Columbia University, New York, NY, Biotechnology Division, Bayer, Berkeley, CA, USA
    Am J Clin Pathol 121:43-50. 2004
    We describe 3 patients who had oral mucosal lesions with features of traumatic eosinophilic granuloma (TEG) and containing CD30+ atypical cells. In 1 patient, the oral lesion was followed by skin nodules...
  32. ncbi Eosinophilic granuloma of the orbit: report of two cases
    Kaan Gunduz
    Department of Ophthalmology, Ankara University Faculty of Medicine, Ankara, Turkey
    J AAPOS 11:506-8. 2007
    ..clinical, radiological, and histopathological findings and treatment results of two infants with orbital eosinophilic granuloma. Both patients presented at 1 year of age with unilateral proptosis, periorbital edema, and a ..
  33. ncbi Percutaneous vertebroplasty for eosinophilic granuloma of the cervical spine in a child
    Hua Qiao Tan
    Department of Radiology, Shanghai Sixth People s Hospital Affiliated to Shanghai Jiao Tong University, No 600, Yi Shan Road, Shanghai, China
    Pediatr Radiol 37:1053-7. 2007
    We report a case of eosinophilic granuloma at the fourth cervical vertebra in a 10-year-old girl presenting with a 1-month history of cervical pain and stiffness...
  34. ncbi Eosinophilic granuloma of spine in adults: a report of 30 cases and outcome
    Wending Huang
    The Spine Center, Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Shanghai, 200003, China
    Acta Neurochir (Wien) 152:1129-37. 2010
    b>Eosinophilic granuloma (EG) of the spine is rare, especially in adults. There had been few large and long-term studies reported in the literature...
  35. ncbi [Eosinophilic granuloma or aggressive periodontitis?]
    A Zaghbani
    Service de médecine dentaire, EPS Farhat Hached, Sousse, Tunisie
    Rev Stomatol Chir Maxillofac 111:49-52. 2010
    b>Eosinophilic granuloma in the jawbones can be confused with aggressive periodontitis or more rarely with inflammatory lesions of dental origin...
  36. ncbi Unusual presentation of mastoid eosinophilic granuloma in a young patient
    S Postovsky
    Department of Pediatric Hematology/Oncology, Rambam Medical Center and Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel
    Pediatr Hematol Oncol 18:283-9. 2001
    b>Eosinophilic granuloma is a well-recognized form of Langerhans cell histiocytosis, most commonly involving the skull bones, usually with an excellent prognosis...
  37. ncbi Thoracoscopic transillumination in chest wall resection
    Francis J Podbielski
    Division of Thoracic Surgery, University of Massachusetts Medical School, Worcester, Massachusetts 01605 2657, USA
    Asian Cardiovasc Thorac Ann 12:171-2. 2004
    ..We describe a hybrid technique that employs video-thoracoscopy and chest wall transillumination to determine the appropriate margin of resection...
  38. ncbi Eosinophilic granuloma of the atlas presenting as torticollis in a child
    Bonaventure B Ngu
    Department of Orthopaedic Surgery, University of Maryland Medical Center, Baltimore, Maryland, USA
    Spine (Phila Pa 1976) 29:E98-100. 2004
    This report describes a case of successful surgical treatment of eosinophilic granuloma of the atlas in a 3.5-year-old boy who presented with torticollis.
  39. ncbi The Langerhans' cell histiocytosis (eosinophilic granuloma) of the cervical spine: a rare diagnosis of cervical pain
    C Simanski
    Department of Surgery, University of Cologne, Cologne, Germany
    Magn Reson Imaging 22:589-94. 2004
    ..Histology of the osteolytic material led to the diagnosis of an eosinophilic granuloma of the cervical spine...
  40. ncbi Eosinophilic granuloma of the skull associated with epidural haematoma: a case report and review of the literature
    Melike Mut
    Departmrnt of Neurosurgery, Hacettepe University Institute of Neurological and Psychiatric Sciences, Sihhiye, 06100 Ankara, Turkey
    Childs Nerv Syst 20:765-9. 2004
    b>Eosinophilic granuloma (EG), a benign bone lesion, represents a focal form of histiocytosis X. Here, the authors report a case of an extremely rare presentation of a solitary EG of the skull.
  41. ncbi Spontaneous resolution of lumbar vertebral eosinophilic granuloma
    M Bavbek
    Department of Neurosurgery, Baskent University Faculty of Medicine, Ankara, Turkey
    Acta Neurochir (Wien) 146:165-7. 2004
    b>Eosinophilic granuloma (EG) is a rare disease but is more common in adults than children. It's often self-limiting. Spinal involvement is rare...
  42. ncbi [Eosinophilic granuloma of the spine]
    G M Kukuk
    Rofo 178:548-9. 2006
  43. ncbi [Unifocal eosinophilic granuloma of the temporal bone]
    A Rodríguez Fernández-Freire
    Servicio ORL, Hospital Universitario Puerta del Mar, Cadiz
    An Otorrinolaringol Ibero Am 34:223-9. 2007
    We present a case of a twelve year old child with a eosinophilic granuloma of the temporal bone. The eosinophilic granuloma is the most frecuent and most benign form of the histiocytosis of the Langerhans cells...
  44. ncbi Qualitative diagnosis of calvarial metastasis by neural network and logistic regression
    Estanislao Arana
    Department of Radiology, Hospital Universitario Dr Peset, Valencia, Spain
    Acad Radiol 11:45-52. 2004
    ..To simplify the diagnostic features used by an artificial neural network compared with logistic regression (LR) in the diagnosis of calvarial metastasis with computed tomography and analyze their accuracy...
  45. ncbi Eosinophilic granuloma with oral manifestations: a case report
    K L Vandana
    Department of Periodontics, College of Dental Sciences, Davangere, Karnataka
    J Indian Soc Pedod Prev Dent 21:105-7. 2003
    b>Eosinophilic granuloma is the most benign disorder of the triad commonly known as histocytosis X...
  46. ncbi [Ischemic eosinophilic granuloma and pulmonary histiocytosis with a regressive course]
    R Gerard
    Clinique d orthopédie et de chirurgie de l appareil moteur, Hopital Cantonal Universitaire de Geneve, 24, Rue Micheli du Crest, 1211 Geneve 14, Suisse
    Rev Chir Orthop Reparatrice Appar Mot 93:501-5. 2007
    ..Focal forms such as eosinophilic granuloma of the bone only require minimal care but the gravity of multisystem forms causing organic dysfunction ..
  47. ncbi Magnetic resonance imaging of bone tumours and mimics: pictorial essay
    Alison R Spouge
    Department of Diagnostic Imaging, University of Western Ontario, London Health Sciences Centre University Campus, 339 Windermere Rd, London, ON N6A 5A5
    Can Assoc Radiol J 54:221-33. 2003
  48. ncbi Eosinophilic granuloma: bilateral temporal bone involvement
    Chester P Barton
    Department of Otolaryngology, U S Air Force Academy Hospital, 4102 Pinion Dr, Colorado Springs, CO 80840, USA
    Ear Nose Throat J 86:342-3. 2007
    b>Eosinophilic granuloma is an uncommon condition that is characterized by unifocal or multifocal osteolytic lesions that often affect the skull...
  49. ncbi Unusual location of eosinophilic granuloma
    Ammar S Haouimi
    Department of Radiology, Medina Maternity and Children s Hospital, Medina Al Munawara, Kingdom of Saudi Arabia
    Saudi Med J 25:1264-6. 2004
    b>Eosinophilic granuloma EG is a well-recognized benign form of Langerhans cell histiocytosis, most commonly involving the skull bones...
  50. ncbi [Solitary eosinophilic granuloma of the orbit: a case report]
    L Harzallah
    Service d Imagerie Medicale, Hôpital Farhat Hached, Sousse, Tunisia
    J Fr Ophtalmol 28:983. 2005
    The authors report a case of eosinophilic granuloma involving the roof and the lateral wall of the left orbit in a 5-year-old boy...
  51. ncbi [Eosinophilic granuloma revealed by torticollis: a case report]
    C Ben Meriem
    Service de Pediatrie, CHU de Fattouma Bourguiba, 5000, Monastir, Tunisie
    Arch Pediatr 13:44-7. 2006
    ..Langerhans cell histiocytose is a rare condition in childhood. It presents in different ways ranging from a single bony disease to a multisystemic disease involving vital organs...
  52. ncbi Eosinophilic granuloma of the skull
    W C J Huysse
    Department of Radiology, Leids Universitair Medisch Centrum, Leiden, The Netherlands
    JBR-BTR 89:134-5. 2006
  53. pmc Osteochondritis (Calvé's disease) of a vertebral body: a rare form of vertebra plana (T. Shisha et al.)
    Michel Benoist
    Department of Orthopaedic Surgery, Rheumatology Section, Hopital Beaujon, 113, Avenue V Hugo, 75116 Paris, France
    Eur Spine J 15:384-5. 2006
  54. ncbi Eosinophilic tumor in a patient with bronchial asthma receiving pranlukast
    Toru Watanabe
    Department of Pediatrics, Niigata City General Hospital, 2 6 1 Shichikuyama, 950 8739 Niigata, Japan
    Eur J Pediatr 166:183-4. 2007
  55. ncbi Primary bone tumors of the spine in children
    Albert J Fenoy
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    J Neurosurg 105:252-60. 2006
    ....
  56. ncbi [Mastoid eosinophilic granuloma: a case report]
    A Filali Adib
    CHU Ibn Sina, Service ORL et Chirurgie Cervico Faciale, Rabat, Maroc
    Rev Laryngol Otol Rhinol (Bord) 126:37-41. 2005
    ..b>Eosinophilic granuloma is a localised form of histiocytosis X, or Langerhans' cells histiocytosis, a benign form with unknown ..
  57. ncbi Eosinophilic granuloma of the atlas and the occipital condyle in an adult
    F Feyaerts
    Dpt of Radiology, Imelda Hospital, Bonheiden, Belgium
    JBR-BTR 90:135. 2007
  58. ncbi [Solid tumours of the vertebral column and spinal cord in children. Reasons and consequences of diagnostic delay]
    Elzbieta Drozyńska
    Klinika Pediatrii, Hematologii, Onkologii i Endokrynologii, Akademia Medyczna, Debinki 7, 80 211 Gdańsk, Poland
    Med Wieku Rozwoj 8:183-91. 2004
    ..Such localisation of neoplastic disease creates problems, connected with the risk of irreversible damage of neurological functions. It is essential to make a proper diagnosis very early...
  59. ncbi Primary eosinophilic granuloma invading the skull base: case report and critical review of the literature
    P Lunardi
    Department of Neurological Sciences, University of Rome, La Sapienza, Italy
    Tumori 82:397-400. 1996
    A case of eosinophilic granuloma of the lesser wing of the sphenoid bone is reported...
  60. ncbi Eosinophilic granuloma in the pediatric spine
    Jeremy D W Greenlee
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242, USA
    Pediatr Neurosurg 43:285-92. 2007
    b>Eosinophilic granuloma (EG) involving the vertebrae in the pediatric population presents a difficult management scenario...
  61. ncbi Solitary eosinophilic granuloma of the calvaria
    F Puzzilli
    Department of Neurological Sciences, Second Chair of Neurosurgery, University of Rome La Sapienza, Italy
    Tumori 84:712-6. 1998
    ..The aim of this study was to define the management of solitary eosinophilic granuloma (EG) of the calvaria in adult patients, in relation to the size and site of the lesion...
  62. ncbi Anterior cervical corpectomy and fusion using miniplate and screws in a 7-year-old child with eosinophilic granuloma of the cervical spine
    M J Sohn
    Department of Neurosurgery, Inha University Medical Center, Inchon, Korea
    Spine (Phila Pa 1976) 26:1193-6. 2001
    STUDY DESIGN: This is a case report of a 7-year-old child with eosinophilic granuloma in the cervical spine, which underwent anterior cervical corpectomy and fusion by using Miniplate and screws...
  63. ncbi Eosinophilic angiocentric fibrosis of the orbit
    Hayyam Kiratli
    Ocular Oncology Service, Department of Ophthalmology, Hacettepe University School of Medicine, Ankara, Turkey
    Clin Experiment Ophthalmol 36:274-6. 2008
    ..She remained stable without recurrence for 32 months. The patient with this exceptionally rare tumour of the orbit benefited from debulking surgery followed by systemic corticosteroids and antihistaminics...
  64. ncbi [Treatment concepts of benign bone tumors and tumor-like bone lesions]
    K D Schaser
    Sektion Muskuloskeletale Tumorchirurgie, Klinik fur Unfall und Wiederherstellungschirurgie, Charite, Campus Virchow Klinikum, Humboldt Universitat, Berlin
    Chirurg 73:1181-90. 2002
    ..e. complication rate, possibilities for reconstructive stabilizations and resultant functional deficits,making the decision a responsible challenge to the orthopedic surgeon...
  65. ncbi Spontaneous resolution of calvarial eosinophilic granuloma in children
    Marcelo Oliveira
    Division of Pediatric Neurosurgery, British Columbia s Children s Hospital, Children and Women s Health Centre, Vancouver, BC, Canada
    Pediatr Neurosurg 38:247-52. 2003
    The recommended treatment for solitary calvarial eosinophilic granuloma (EG) is surgical resection by curettage, craniectomy or craniotomy...
  66. ncbi [The role of medical imaging in paleoanthropology]
    P Vidal
    INRAP, Laboratoire d Anatomie, Faculte de Medecine, Vandoeuvre les Nancy, France
    J Radiol 89:499-506. 2008
    ..These include one case of eosinophilic granuloma, one case of Ewing sarcoma, and one case of secondary hypertrophic osteoarthropathy...
  67. ncbi Treatment of recurrent eosinophilic granuloma with systemic therapy
    Alice Song
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida, U S A
    Ophthal Plast Reconstr Surg 19:140-4. 2003
    To describe the systemic treatment of recurrent eosinophilic granuloma.
  68. ncbi [Langerhans's cell histiocytosis in otorhinolaryngology]
    F P García-Ortega
    Servicio de ORL, Hospital General de Elda, Alicante
    Acta Otorrinolaringol Esp 52:351-4. 2001
    ..The head and neck are frequent sites of initial presentation. We present two cases of LCH with otorhinolaryngologic symptoms. Current recommendations for diagnosis, evaluation and treatment of LCH are also discussed...
  69. doi [Cutaneous localizations in child Langerhans cell histiocytosis]
    M Rybojad
    Service de Dermatologie 2, AP HP, Hopital Saint Louis, 1, avenue Claude Vellefaux, 75475 Paris Cedex 10
    Arch Pediatr 15:523-5. 2008
  70. ncbi [Eosinophilic granuloma of the cervical spine: case report]
    Manoel Baldoino Leal Filho
    Hospital Getúlio Vargas e Universidade Federal do Piaui, Teresina, Brasil
    Arq Neuropsiquiatr 61:141-3. 2003
    b>Eosinophilic granuloma (EG) is a benign condition of histocytes proliferation localized or multifocal. It is presents in the cervical spine in 1.5%-20% of the cases of EG...
  71. ncbi [Idiopathic eosinophilic orbital pseudotumor of the lacrimal gland in a child]
    Nicolas Feltgen
    Universitäts Augenklinik Freiburg
    Klin Monbl Augenheilkd 219:458-61. 2002
    ..In contrast to adults, children very rarely develop an associated systemic disorder. The disease is generally treated with steroids. Little is known about the natural course of idiopathic orbital pseudotumors in childhood...
  72. ncbi Eosinophilic granuloma of the jaws: a report of three cases
    J Bonet
    , Hospital Infantil Universitario La Fe, Valencia,
    Med Oral 6:218-24. 2001
    Three cases of eosinophilic granuloma involving two boys and a girl are reported. Osteolytic lesions of the jaws were seen in all three patients. The two boys presented mandibular lesions, while the girl had lesions in both jaws...
  73. ncbi Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 5-2002. A 15-year-old boy with a retro-orbital mass and impaired vision
    Craig A Hurwitz
    Division of Pediatric Hematology Oncology, Barbara Bush Children s Hospital, Portland, ME, USA
    N Engl J Med 346:513-20. 2002
  74. ncbi Cranial fasciitis of childhood
    Harold F Keyserling
    Department of Radiology, University of North Carolina Hospitals, Chapel Hill, NC 27559, USA
    AJNR Am J Neuroradiol 24:1465-7. 2003
    ..Herein, we include the first description of this entity's diffusion-weighted imaging appearance. Although rare, cranial fasciitis can mimic more aggressive processes both clinically and radiographically...
  75. ncbi Torticollis secondary to posterior fossa and cervical spinal cord tumors: report of five cases and literature review
    Sefer Kumandas
    Department of Pediatric Neurology, Erciyes University Medical School, Kayseri, Turkey
    Neurosurg Rev 29:333-8; discussion 338. 2006
    ..an astrocytoma originating from the bulbus and extending into the posterior fossa, and another case of a eosinophilic granuloma located extradurally through the anterior and posterior portions of the vertebral bodies from C3 to C7 ..
  76. ncbi Bilateral sequential orbital involvement by eosinophilic granuloma
    Hakan Demirci
    Oncology Service, Wills Eye Hospital, 900 Walnut St, Philadelphia, PA 19107, USA
    Arch Ophthalmol 120:978-9. 2002
  77. ncbi [Clinical results and the mechanism of bone healing for the repair of bone defects due to tumor resection with novel interporous TCP]
    Hongxun Sang
    Department of Orthopedics, Xijing Hospital, Forth Military Medical University, Xi an Shaanxi, 710032, P R China
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 22:463-7. 2008
    ..To investigate the clinical results and the mechanism of bone healing for the repair of bone defects following tumor resection with novel interporous TCP bone graft, and to test the hypothesis of "structural transplantation"...
  78. ncbi Craniovertebral junction neoplasms in the pediatric population
    Arnold H Menezes
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 1824 JPP, Iowa City, IA 52242, USA
    Childs Nerv Syst 24:1173-86. 2008
    ..The incidence of tumors at the craniovertebral junction in the pediatric population is low. Because of the variable pathology and the rarity of these tumors, ideal therapies are only now being defined...
  79. ncbi Primary chest wall tumors: early and long-term results of surgical treatment
    K Athanassiadi
    Department of Thoracic and Vascular Surgery, Evangelismos General Hospital, Hellas, Athens, Greece
    Eur J Cardiothorac Surg 19:589-93. 2001
    ..A retrospective study of primary chest wall tumors (PCWTs/CWTs) was conducted to review their clinical, radiological and pathological features, as well as the early and long-term results of surgical management...
  80. ncbi [Chondroma of the skull base and maxilla]
    Aleksandar Kiralj
    Klinicki centar Vojvodine, Klinika za maksilofacijalnu hirurgiju, Medicinski fakultet Novi Sad
    Med Pregl 60:649-51. 2007
    ..On a radiograph, the tumor appears as a cyst-like radiolucent lesion, while some are sclerotic. The borders are usually ill-defined. Irregular calcifications may be seen with radiolucencies and then it is an osteochondroma...
  81. ncbi Langerhans cell histiocytosis presented as bilateral otitis media and mastoiditis
    Charalampos E Skoulakis
    Departments of Otolaryngology, General Hospital of Volos, Volos, Greece
    Turk J Pediatr 50:70-3. 2008
    ..term LCH or histiocytosis X refers to three separate illnesses (listed in order of increasing severity): eosinophilic granuloma, Hand-Schüller-Christian disease and Letterer-Siwe disease...
  82. ncbi Leukotrienes, LTC4 and LTB4, in bronchoalveolar lavage in bronchial asthma and other respiratory diseases
    A J Wardlaw
    Department of Allergy, Cardiothoracic Institute, London, England
    J Allergy Clin Immunol 84:19-26. 1989
    ..one with extrinsic allergic alveolitis, one with sulphonamide-induced pneumonia, and one patient with eosinophilic granuloma. The concentrations of LTB4 (but not LTC4) were significantly greater in patients with CFA compared with ..
  83. ncbi Intralesional corticosteroid therapy for mandibular Langerhans cell histiocytosis preserving the intralesional tooth germ
    Antonios Moralis
    Klinik und Poliklinik fur Mund, Kiefer und Gesichtschirurgie, Universitat Regensburg, Franz Josef Strauss Allee 11, Regensburg, Germany
    Oral Maxillofac Surg 12:105-11. 2008
    ..The course of the disease determines the treatment and prognosis. Solitary forms (eosinophilic granuloma) and limited multilocational lesions may be treated successfully with local surgical intervention and ..
  84. ncbi Langerhans cell histiocytosis: literature review and descriptive analysis of oral manifestations
    Cristina Madrigal-Martínez-Pereda
    Departamento de Medicina y Cirugía Bucofacial, Facultad de Odontologia, UCM, Madrid, Spain
    Med Oral Patol Oral Cir Bucal 14:E222-8. 2009
    ..subacute or acute disseminated form), Hand-Schüller-Christian disease (disseminated chronic form) and eosinophilic granuloma (localized chronic form)...
  85. ncbi Benign bone cyst mimicking skeletal metastasis on (18)F-FDG-PET
    Aditi Khurana
    Division of PET Imaging, Molecular Imaging and Research Centre, Institute of Nuclear Medicine and Allied Sciences, Delhi, India
    Hell J Nucl Med 12:179-80. 2009
    ..Benign lesions like eosinophilic granuloma, fibrous dysplasia, aneurysmal bone cyst, and giant cell tumor, also show increased (18)F-FDG uptake...
  86. ncbi Oral Langerhans cell histiocytosis in Malaysian children: a 40-year experience
    Ajura bt Abdul Jalil
    Stomatology Unit, Cancer Research Centre, Institute for Medical Research, 50588 Jalan Pahang, Kuala Lumpur, Malaysia
    Int J Paediatr Dent 19:349-53. 2009
    ..Oral Langerhans cell histiocytosis is generally seen in children...
  87. pmc Treatment and outcome of vertebral Langerhans cell histiocytosis at the Children's Hospital of Eastern Ontario
    Christopher W Brown
    Division of Orthopaedic Surgery, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont
    Can J Surg 48:230-6. 2005
    ....
  88. ncbi Langerhans' cell histiocytosis: pathology, imaging and treatment of skeletal involvement
    E Michel Azouz
    Pediatric Radiology Section, Department of Radiology, University of Miami, R 109, P O Box 016960, Miami, FL 33101, USA
    Pediatr Radiol 35:103-15. 2005
    Langerhans' cell histiocytosis (LCH) is manifested in a variety of ways, the most common being the eosinophilic granuloma, a localized, often solitary bone lesion that occurs predominantly in the pediatric age group...
  89. ncbi Maxillofacial manifestations of Langerhans cell histiocytosis: a clinical and therapeutic analysis of 10 patients
    A Eckardt
    Department of Oral and Maxillofacial Surgery, Hannover Medical University, Carl Neuberg Strasse 1, 30625 Hannover, Germany
    Oral Oncol 39:687-94. 2003
    ..X) includes the clinical syndromes Hand-Schueller-Christian syndrome, Abt-Letterer-Siwe syndrome, and eosinophilic granuloma. The paper gives an overview of current diagnostic and treatment strategies of LCH...
  90. ncbi Intestinal localization of anisakiasis manifested as acute abdomen
    P Caramello
    Infectious Diseases Unit A, Ospedale Amedeo di Savoia, C so Svizzera 164, 10149 Torino, Italy
    Clin Microbiol Infect 9:734-7. 2003
    ..gastroallergic anisakiasis'), and direct tissue damage, due to invasion of the gut wall, development of eosinophilic granuloma, or perforation (gastric or intestinal anisakiasis)...
  91. pmc A case of eosinophilic granuloma of the skull in an adult man: a case report
    Panagiotis V Kitsoulis
    Department of Anatomy Histology Embryology, Medical School, University of Ioannina, Greece
    Cases J 2:9144. 2009
    b>Eosinophilic granuloma is very rare benign bone tumor which presents in more than 90% in children under the age of ten. There is predominance for males. It is usually found at flat and long bones...
  92. ncbi Intralesional infiltration of corticosteroids in the treatment of localised langerhans' cell histiocytosis of the mandible Report of known cases and three new cases
    Th F Putters
    Department of Oral and Maxillofacial Surgery, University Hospital Groningen, 9700 RB Groningen, The Netherlands
    Int J Oral Maxillofac Surg 34:571-5. 2005
    ..Bone can be involved as a part of generalised disease or as a separate entity, formerly known as eosinophilic granuloma. The clinical cause of localised LCH (LLCH) to bone is generally benign...
  93. ncbi [Langerhans' cell histiocytosis--diagnostic and treatment difficulties]
    Bogusława Orzechowska-Wylegała
    Silesian Medical University of Katowice, Chair and Department of Maxillofacial Surgery, Poland
    Pol Merkur Lekarski 24:439-42. 2008
    ..LCH may appear as an isolated leasion or as a widespread systemic disease. Focus in the bone as eosinophilic granuloma can be separate or be involved only as a part of generalized disease...
  94. ncbi Differential diagnosis of benign tumors and tumor-like lesions in the spine. Own cases and review of the literature
    S M Knoeller
    Department of Orthopedic Surgery, University Hospital Freiburg, Germany
    Neoplasma 51:117-26. 2004
    ..lesions of the spine including osteochondroma, osteoblastoma, osteoid osteoma, aneurysmal bone cyst, eosinophilic granuloma, hemangioma, and giant cell tumor, their appearance relation to the age and location in the spine were ..
  95. ncbi Persistent long-term human herpesvirus 6 (HHV-6) infection in a patient with langerhans cell histiocytosis
    Marta Csire
    Division of Virology, National Center for Epidemiology, Budapest, H 1097, Hungary
    Pathol Oncol Res 13:157-60. 2007
    Langerhans cell histiocytosis (eosinophilic granuloma) was first diagnosed in the adolescence of a male patient presented. Several years later persisting human herpesvirus 6 (HHV-6) infection was recognized...
  96. ncbi Pediatric rib lesions: a 13-year experience
    Sendia Kim
    Department of Surgery, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
    J Pediatr Surg 43:1781-5. 2008
    ..Rib lesions in the pediatric population are rare but significant processes and are often neoplastic...
  97. ncbi Hepatic capillariasis in Maine presenting as a hepatic mass
    Jennifer Klenzak
    Division of Nephrology, Department of Medicine, Maine Medical Center, Portland, Maine 04102, USA
    Am J Trop Med Hyg 72:651-3. 2005
    ..The patient underwent open laparotomy for resection of the mass. He was found to have an eosinophilic granuloma in the liver; further evaluation revealed degenerating Capillaria hepatica...
  98. ncbi Langerhans cell histiocytosis manifesting as recurrent simultaneous bilateral spontaneous pneumothorax in early infancy
    Samin Alavi
    Department of Pediatric Hematology Oncology, Mofid Children s Hospital, Shahid Beheshti Medical University, Tehran, Iran
    Pediatr Int 49:1020-2. 2007
    ..Historically, LCH included four main clinical forms: Letter-Siwe disease, Hand-Schuller-Christian disease, eosinophilic granuloma (together grouped as histiocytosis) and Hashimoto-Pritzker disease...
  99. ncbi Immunocytochemical investigation of Langerin (CD207) is a valuable adjunct in the cytological diagnosis of Langerhans cell histiocytosis of the thyroid
    Jeremias Wohlschlaeger
    Department of Pathology and Neuropathology, University Hospital of Essen, University of Duisburg Essen, Hufelandstrasse 55, 45147 Essen, Germany
    Pathol Res Pract 205:433-6. 2009
    ..Langerhans cell histiocytosis (LCH) is an uncommon disease encompassing three clinically different entities: eosinophilic granuloma, Hand-Schüller-Christian disease, and Abt-Letterer-Siewe disease...
  100. ncbi [Etiology, diagnosis and treatment analysis of 37 cases with orbital fistula]
    Ting ting Lin
    Tianjin Medical University Eye Center, Tianjin 300070, China
    Zhonghua Yi Xue Za Zhi 89:1774-8. 2009
    ..To present some instruction in diagnosis and treatment of the orbital fistula by analyze the clinical manifestation...
  101. pmc Craniopharyngioma
    Matthew R Garnett
    Department of Paediatric Neurosurgery, Necker Hospital for Sick Children, Paris, France
    Orphanet J Rare Dis 2:18. 2007
    ..diagnosis includes other tumours in this region (pituitary adenoma), infectious or inflammatory processes (eosinophilic granuloma), vascular malformations (aneurysm) and congenital anomalies (Rathke's cleft cyst)...

Research Grants2

  1. Improving Physician Adherence to Asthma Guidelines
    Gregory Diette; Fiscal Year: 2005
    ..usual generalist care; and 3) How care should be organized for management of chronic diseases. ..
  2. Complement inhibition in experimental autoimmune uveitis
    RUSSELL READ; Fiscal Year: 2006
    ..abstract_text> ..