platybasia

Summary

Summary: A developmental deformity of the occipital bone and upper end of the cervical spine, in which the latter appears to have pushed the floor of the occipital bone upward. (Dorland, 27th ed)

Top Publications

  1. ncbi Basilar invagination, a rare condition mimicking posterior circulation stroke
    Anjali Bhagra
    Neurocrit Care 5:213-4. 2006
  2. ncbi Combined anterior and posterior approach for managing basilar invagination associated with type I Chiari malformation
    Mehmet Zileli
    Ege University Faculty of Medicine, Department of Neurosurgery, Bornova, Izmir, Turkey
    J Spinal Disord Tech 15:284-9. 2002
  3. ncbi Spontaneous regression of syringomyelia in Hajdu-Cheney syndrome with severe platybasia. Case report
    Federico Di Rocco
    Division of Pediatric Neurosurgery, Department of Neurosurgery, Jikei University School of Medicine, Tokyo, Japan
    J Neurosurg 103:194-7. 2005
  4. ncbi Neuronavigation-assisted transoral-transpharyngeal approach for basilar invagination--two case reports
    Hasan Caglar Ugur
    Department of Neurosurgery, Faculty of Medicine, Ankara University, Turkey
    Neurol Med Chir (Tokyo) 46:306-8. 2006
  5. ncbi Basilar invagination: craniocervical instability treated with cervical traction and occipitocervical fixation. Case report
    Ricardo V Botelho
    Spinal Group, Neurosurgical Service, Hospital do Servidor Publico Estadual de Sao Paulo, Brazil
    J Neurosurg Spine 7:444-9. 2007
  6. ncbi Evaluation of platybasia with MR imaging
    Robert A Koenigsberg
    Department of Radiologic Sciences, Drexel University College of Medicine, Philadelphia, PA 19102 1192, USA
    AJNR Am J Neuroradiol 26:89-92. 2005
  7. ncbi Posterior cranial fossa volume in patients with rickets: insights into the increased occurrence of Chiari I malformation in metabolic bone disease
    R Shane Tubbs
    Department of Cell Biology, University of Alabama at Birmingham, Children s Hospital, Birmingham, Alabama 35233, USA
    Neurosurgery 55:380-3; discussion 383-4. 2004
  8. ncbi Craniocervical CT and MR imaging of Schwartz-Jampel syndrome
    Sarah S Samimi
    Saint Louis University School of Medicine, Cardinal Glennon Children s Hospital, St Louis, MO, USA
    AJNR Am J Neuroradiol 24:1694-6. 2003
  9. ncbi Treatment of basilar invagination by atlantoaxial joint distraction and direct lateral mass fixation
    Atul Goel
    Department of Neurosurgery, King Edward Memorial Hospital and Seth G S Medical College, Mumbai, India
    J Neurosurg Spine 1:281-6. 2004
  10. ncbi Possible mechanisms and gene involvement in speech problems in the 22q11.2 deletion syndrome
    J C C Widdershoven
    Department of Plastic, Reconstructive and Hand Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Plast Reconstr Aesthet Surg 61:1016-23. 2008

Research Grants

  1. HDAd-mediated gene therapy for hemophilia B
    Nicola Brunetti Pierri; Fiscal Year: 2008

Scientific Experts

Detail Information

Publications104 found, 100 shown here

  1. ncbi Basilar invagination, a rare condition mimicking posterior circulation stroke
    Anjali Bhagra
    Neurocrit Care 5:213-4. 2006
  2. ncbi Combined anterior and posterior approach for managing basilar invagination associated with type I Chiari malformation
    Mehmet Zileli
    Ege University Faculty of Medicine, Department of Neurosurgery, Bornova, Izmir, Turkey
    J Spinal Disord Tech 15:284-9. 2002
    ..If there is a marked anterior compression, anterior transoral and posterior decompression, fusion, and instrumentation is an optimal strategy for treating patients with basilar invagination associated with type I Chiari malformation...
  3. ncbi Spontaneous regression of syringomyelia in Hajdu-Cheney syndrome with severe platybasia. Case report
    Federico Di Rocco
    Division of Pediatric Neurosurgery, Department of Neurosurgery, Jikei University School of Medicine, Tokyo, Japan
    J Neurosurg 103:194-7. 2005
    ..In some cases, progressive platybasia can occur and can lead to Chiari malformation with an obstruction of cerebrospinal fluid flow...
  4. ncbi Neuronavigation-assisted transoral-transpharyngeal approach for basilar invagination--two case reports
    Hasan Caglar Ugur
    Department of Neurosurgery, Faculty of Medicine, Ankara University, Turkey
    Neurol Med Chir (Tokyo) 46:306-8. 2006
    ..Both patients had an uneventful postoperative course. The transoral-transpharyngeal approach with the neuronavigation system provides safe exposure and decompression for basilar invagination...
  5. ncbi Basilar invagination: craniocervical instability treated with cervical traction and occipitocervical fixation. Case report
    Ricardo V Botelho
    Spinal Group, Neurosurgical Service, Hospital do Servidor Publico Estadual de Sao Paulo, Brazil
    J Neurosurg Spine 7:444-9. 2007
    ....
  6. ncbi Evaluation of platybasia with MR imaging
    Robert A Koenigsberg
    Department of Radiologic Sciences, Drexel University College of Medicine, Philadelphia, PA 19102 1192, USA
    AJNR Am J Neuroradiol 26:89-92. 2005
    b>Platybasia, or abnormal obtuseness of the basal angle, was first measured on plain skull images. At present, evaluation of the brain and skull more commonly involves CT and MR imaging...
  7. ncbi Posterior cranial fossa volume in patients with rickets: insights into the increased occurrence of Chiari I malformation in metabolic bone disease
    R Shane Tubbs
    Department of Cell Biology, University of Alabama at Birmingham, Children s Hospital, Birmingham, Alabama 35233, USA
    Neurosurgery 55:380-3; discussion 383-4. 2004
    ..The present study measures the posterior fossa volume in children with rickets to verify previous case reports indicting a small posterior fossa as the cause for an increased rate of CIM in children with rickets...
  8. ncbi Craniocervical CT and MR imaging of Schwartz-Jampel syndrome
    Sarah S Samimi
    Saint Louis University School of Medicine, Cardinal Glennon Children s Hospital, St Louis, MO, USA
    AJNR Am J Neuroradiol 24:1694-6. 2003
    ..of an adolescent male patient with Schwartz-Jampel syndrome, CT and MR imaging revealed basilar invagination, platybasia, Chiari I malformation, hyperpneumatized mastoids with intramastoid dural sinuses, platyspondyly, bulbous zygoma,..
  9. ncbi Treatment of basilar invagination by atlantoaxial joint distraction and direct lateral mass fixation
    Atul Goel
    Department of Neurosurgery, King Edward Memorial Hospital and Seth G S Medical College, Mumbai, India
    J Neurosurg Spine 1:281-6. 2004
    ....
  10. ncbi Possible mechanisms and gene involvement in speech problems in the 22q11.2 deletion syndrome
    J C C Widdershoven
    Department of Plastic, Reconstructive and Hand Surgery, University Medical Centre Utrecht, Utrecht, The Netherlands
    J Plast Reconstr Aesthet Surg 61:1016-23. 2008
    ..This may be due to a number of factors such as adenoid hypoplasia, muscle hypotonia, platybasia, upper airway asymmetry, and neuroanatomical abnormalities...
  11. ncbi Chromosome 22q11.2 deletion and phenotypic features in 30 patients with conotruncal heart defects
    Murat Derbent
    Department of Pediatrics, Baskent University Faculty of Medicine, Ankara, Turkey
    Am J Med Genet A 116:129-35. 2003
    ..Radiographs of this patient showed platybasia, complete fusion of C2-C3, and posterior fusion of the T1-T2 vertebrae...
  12. pmc Spondylocarpotarsal synostosis: long-term follow-up of a case due to FLNB mutations
    Nicola Brunetti-Pierri
    Department of Human and Molecular Genetics, Baylor College of Medicine, Houston, TX 77030, USA
    Am J Med Genet A 146:1230-3. 2008
  13. ncbi A case of basilar impression complicated with left frontal meningioma
    Shunji Asamoto
    Department of Neurosurgery, Justus Liebig University, Giessen, Germany
    No Shinkei Geka 31:1003-7. 2003
    ..Subsequently, the tumor was resected via the left frontal approach using microsurgical technique. Histological examination disclosed fibroblastic meningioma...
  14. ncbi Basilar impression associated with impacted cisterna magna, spastic paraparesis and distress of balance
    Helio A G Teive
    Arq Neuropsiquiatr 64:1053; author reply 1053. 2006
  15. ncbi Treatment of primary basilar invagination by cervical traction and posterior instrumented reduction together with occipitocervical fusion
    Xinsheng Peng
    Spine Section Department of Orthopaedic Surgery, First Affiliated Hospital of Sun Yat sen University, Guangzhou, China
    Spine (Phila Pa 1976) 36:1528-31. 2011
    ....
  16. ncbi Cranial base abnormalities in osteogenesis imperfecta: phenotypic and genotypic determinants
    Moira S Cheung
    Genetics Unit, Shriners Hospital for Children, Montreal, Quebec, Canada
    J Bone Miner Res 26:405-13. 2011
    ..We did not find evidence for the hypothesis that bisphosphonate treatment protects against skull base abnormalities...
  17. ncbi Basilar impression associated with impacted cisterna magna, spastic paraparesis and distress of balance: case report
    José Alberto Gonçalves da Silva
    Neurosurgical Unit, Hospital Santa Isabel, Joao Pessoa, PB, Brazil
    Arq Neuropsiquiatr 64:668-71. 2006
    ..Six months after posterior fossa decompression there was the disappearance of nuchal rigidity, vertigo, spastic paraparesis and improvement of balance. Nevertheless hyperreflexia and diminished pallesthesia of the lower limbs persisted...
  18. ncbi [A complex of skull base and cervical spine anomalies and Chiari type I malformation]
    N E Krupina
    Zh Nevrol Psikhiatr Im S S Korsakova 102:3-7. 2002
    ..spine anomalies identified in the CMI patients into 3 groups: 1) primary anomalies (basilar invagination, platybasia, atlantal assimilation) predisposing to CMI development; frequent occurrence and reliable interrelation between ..
  19. ncbi Posterior fossa decompression with tonsillectomy in 104 cases of basilar impression, Chiari malformation and/or syringomyelia
    José Alberto Gonçalves da Silva
    Neurosurgical Division of Hospital Unimed, João Pessoa PB, Brazil
    Arq Neuropsiquiatr 69:817-23. 2011
    ..A significant upward migration of the posterior fossa structures was detected by postoperative magnetic resonance imaging...
  20. ncbi [Surgical management of syringomyelia associated with Arnold-Chiari malformation, primary IgA deficiency and chromosomal abnormality--a case report]
    A Keyaki
    Dpartment of Neurosurgery and Neurology, Tenri Hospital, Nara, Japan
    Nihon Geka Hokan 59:161-7. 1990
    ..Plain craniogram of lateral view showed small posterior cranial fossa with low positioned inion and platybasia. MRI with T1-weighted images in sagittal plane revealed tonsillar herniation reaching C1 and syrinx extending ..
  21. ncbi [An analysis of surgical outcome and influencing factors in patients of congenital basilar invagination with atlantal-axial dislocation: report of 120 cases]
    Xing Wen Wang
    Department of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing 100053, China
    Zhonghua Wai Ke Za Zhi 51:207-10. 2013
    ..To investigate the surgical outcome and its influencing factors in patients of congenital basilar invagination (BI) with atlanto-axial dislocation (AAD)...
  22. ncbi Stroke due to a fusiform aneurysm of the cervical vertebral artery: case report
    S Suzuki
    Department of Neurosurgery, Kyushu University Hospital, Fukuoka, Japan
    Neuroradiology 40:19-22. 1998
    ..Associated minor anomalies included fusion of the vertebral bodies of C5 and C6, cervical rib and platybasia. The left VA arose directly from the aortic arch and entered the transverse foramen at the C4 level...
  23. ncbi Distraction, compression, and extension reduction of basilar invagination and atlantoaxial dislocation: a novel pilot technique
    P Sarat Chandra
    Department of Neurosurgery, All India Institute of Medical Sciences AIIMS, New Delhi, India
    Neurosurgery 72:1040-53; discussion 1053. 2013
    ..The management of basilar invagination (BI) and atlantoaxial dislocation (AAD) is a challenge...
  24. ncbi Absence of correlation between infantile hypotonia and foramen magnum size in achondroplasia
    K K Reynolds
    Department of Medical Genetics, University of Wisconsin, 1500 Highland Avenue, Madison, WI 53705, USA
    Am J Med Genet 101:40-5. 2001
    ..We found no correlation. These results suggest that there is no direct relationship and foraminal size does not affect severity of hypotonia. Other potential explanations for this infantile hypotonia are considered...
  25. ncbi Magnetic resonance imaging study of the craniocervical junction
    A Tassanawipas
    Department of Orthopedic Surgery, Phramongkutklao College of Medicine, Bangkok, Thailand
    J Orthop Surg (Hong Kong) 13:228-31. 2005
    ....
  26. pmc Paget's disease of the spine and its management
    A G Hadjipavlou
    Department of Orthopaedic Surgery, University of Crete Medical School, Heraklion, Greece
    Eur Spine J 10:370-84. 2001
    ..myelopathy by pagetic bone overgrowth, pagetic intraspinal soft tissue overgrowth, ossification of epidural fat, platybasia, spontaneous bleeding, sarcomatous degeneration and vertebral fracture or subluxation...
  27. ncbi Application of neuromuscular blockade and intraoperative 3D imaging in the reduction of basilar invagination
    Nader S Dahdaleh
    Department of Neurosurgery, University of Iowa College of Medicine, Iowa City, Iowa 52442, USA
    J Neurosurg Pediatr 9:119-24. 2012
    ..Reducible lesions obviate a ventral decompression and require a dorsal-only approach for stabilization with or without a suboccipital decompression...
  28. ncbi [The role of platybasia in trigeminal neuralgia]
    J Abarca-Olivas
    Servicio de Neurocirugia, Hospital General Universitario de Alicante, E 03010 Alicante, Espana
    Rev Neurol 49:630-2. 2009
    ..However, several cases of skull base deformities in patients with ITN have been reported in our bibliographic review. AIM. To compare the existence of platybasia between a group of patients with ITN and a randomized control group.
  29. ncbi Sublabial approach for the treatment of symptomatic basilar impression in a patient with Klippel-Feil syndrome
    Chetan Bettegowda
    Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Neurosurgery 69:ons77-82; discussion ons82. 2011
    ..Symptomatic BI is often difficult to treat surgically secondary to the anatomic variants associated with many of the coinciding congenital syndromes...
  30. ncbi [Occipitocervical fusion in rheumatoid arthritis]
    M Rittmeister
    ,
    Orthopade 30:932-6. 2001
    ..As a result of fusion, the dens axis is unable to exert compression on the spinal cord with increased neck flexion...
  31. ncbi Endoscopic transnasal odontoidectomy combined with posterior reduction to treat basilar invagination: technical note
    Yong Yu
    Department of Neurosurgery, Zhongshan Hospital, Fudan University, Shanghai, China
    J Neurosurg Spine 19:637-43. 2013
    ..The purpose of this report is to validate the effectiveness of this treatment algorithm in selected cases and describe several operative nuances and pearls based on the authors' experience...
  32. pmc Principles of management of osteometabolic disorders affecting the aging spine
    Alexander G Hadjipavlou
    School of Health Sciences, University of Crete, Department of Orthopaedic Surgery and Traumatology, University General Hospital, PO Box 1352, 71110, Heraklion, Crete, Greece
    Eur Spine J 12:S113-31. 2003
    ..myelopathy by pagetic bone overgrowth, pagetic intraspinal soft tissue overgrowth, ossification of epidural fat, platybasia, spontaneous bleeding, sarcomatous degeneration and vertebral fracture or subluxation...
  33. ncbi Reversal of longstanding musculoskeletal changes in basilar invagination after surgical decompression and stabilization
    Atul Goel
    Department of Neurosurgery, King Edward Memorial Hospital and Seth G S Medical College, Parel, Mumbai, India
    J Neurosurg Spine 10:220-7. 2009
    ..The implications of such an analysis in understanding the pathogenesis of a number of features that are characteristically associated with basilar invagination are evaluated...
  34. ncbi Transoral approach and its superior extensions to the craniovertebral junction malformations: surgical strategies and results
    Paolo Perrini
    Neurosurgical Department, University of Pisa, Pisa, Italy
    Neurosurgery 64:331-42; discussion 342. 2009
    ..To review our experience with the surgical management of craniovertebral junction malformations, focusing on the selection of surgical approach, management of the associated Chiari malformation, and postoperative instability...
  35. ncbi Platybasia and Klippel Feil-syndrome: case report
    Azra Alajbegovic
    University Department of Neurology, Sarajevo University Clinical Center, Sarajevo, Bosnia and Herzegovina
    Acta Clin Croat 51:255-9. 2012
    A case is presented of a 35-year-old woman diagnosed with platybasia associated with Klippel-Feil syndrome type I...
  36. pmc Surgical treatment of Klippel-Feil syndrome with basilar invagination
    Nobuhide Ogihara
    Department of Orthopaedic Surgery, School of Medicine, Shinshu University, 3 1 1 Asahi, Matsumoto City, Nagano, 390 8621, Japan
    Eur Spine J 22:S380-7. 2013
    ..Especially in basilar invagination (BI), which is a dislocation of the dens in an upper direction, compression of the spinomedullary junction from the ventral side results in paralysis, and treatment is required...
  37. ncbi Basilar impression as a possible cause of cerebellar stroke: case report
    Marina Roje-Bedeković
    University Department of Neurology, Sestre milosrdnice University Hospital Center, Zagreb, Croatia
    Acta Clin Croat 50:577-80. 2011
    ....
  38. pmc Angular craniometry in craniocervical junction malformation
    Ricardo Vieira Botelho
    Post graduation Program in Health Sciences IAMSPE São Paulo, Sao Paulo, Brazil
    Neurosurg Rev 36:603-10; discussion 610. 2013
    ..The Chiari malformation group does not show significant differences when compared with normal controls. Platybasia occurred only in basilar invagination and is suggested to be more prevalent in type II than in type I...
  39. ncbi Symptomatic intracranial hypertension and prolonged hypocalcemia following treatment of Paget's disease of the skull with zoledronic acid
    Bruno Ferraz-de-Souza
    Unidade de Doenças Osteometabólicas, Servico de Endocrinologia, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
    J Bone Miner Metab 31:360-5. 2013
    ..Head CT and MRI revealed hydrocephalus with cerebellar tonsillar herniation, platybasia and basilar invagination...
  40. ncbi Endoscopic image-guided transcervical odontoidectomy: outcomes of 15 patients with basilar invagination
    Hormuzdiyar H Dasenbrock
    School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287, USA
    Neurosurgery 70:351-9; discussion 359-60. 2012
    ..Ventral decompression with posterior stabilization is the preferred treatment for symptomatic irreducible basilar invagination. Endoscopic image-guided transcervical odontoidectomy (ETO) may allow for decompression with limited morbidity...
  41. ncbi Giant intradiploic pseudomeningocele of occipital bone
    Rajinder Kumar
    Department of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India
    J Neurosurg Pediatr 9:82-5. 2012
    ..Early diagnosis and treatment is essential. The authors suggest that this condition should be treated early, as for growing skull fractures...
  42. ncbi Klippel-Feil syndrome and Dandy-Walker malformation
    A Karaman
    Erzurum Nenehatun Obstetrics and Gynecology Hospital, Department of Medical Genetics, Erzurum, Turkey
    Genet Couns 22:411-5. 2011
    The Klippel-Feil deformity is a complex of osseous and visceral anomalies, which include low hairline, platybasia, fused cervical vertebrae with a short neck, and deafness...
  43. ncbi Retrospective study of patients with Chiari: malformation submitted to surgical treatment
    Mario Augusto Taricco
    Neurosurgery Division, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
    Arq Neuropsiquiatr 66:184-8. 2008
    ..Those CM cases associated with other abnormalities, such as SM and BI, probably need complementary techniques which will be the theme for new prospective studies...
  44. ncbi High cervical C3-4 'disc' compression associated with basilar invagination
    Atul Goel
    Department of Neurosurgery, King Edward Memorial Hospital and Seth G S Medical College, Parel, Mumbai, India
    Neurol India 56:68-70. 2008
    ..The patient had marked clinical recovery, despite the fact that no direct procedure was done for C3-4 disc decompression. The case suggests that C3-4 disc changes could be secondary to primary instability at the craniovertebral junction...
  45. ncbi Transoral approach to the craniovertebral junction
    José Alberto Landeiro
    Hospital da Força Aérea do Galeão, Rio de Janeiro, RJ, Brasil
    Arq Neuropsiquiatr 65:1166-71. 2007
    ..In patients with marked ventral compression, the transoral approach provides direct access to the anterior face of the craniovertebral junction and effective means for odontoidectomy...
  46. ncbi Specific entities affecting the craniocervical region: osteogenesis imperfecta and related osteochondrodysplasias: medical and surgical management of basilar impression
    Arnold H Menezes
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, 1824 JPP, Iowa City, IA 52242, USA
    Childs Nerv Syst 24:1169-72. 2008
    ..Osteogenesis imperfecta (OI) is an inheritable disorder of bone development caused by defective collagen synthesis. The attendant basilar impression or secondary basilar invagination is uncommon but can be devastating...
  47. ncbi Cervical vertebrae anomalies-incidental findings on lateral cephalograms
    Priyavrat Soni
    Division of Orthodontics, Department of Dental Surgery, Armed Forces Medical College, Pune, India
    Angle Orthod 78:176-80. 2008
    ..Patients were educated about the likely future course of these findings. Specialist follow-up was advised to all the patients...
  48. ncbi Basilar impression and osteogenesis imperfecta: a 21-year retrospective review of outcomes in 20 patients
    Ahmed G Ibrahim
    Victor Horsley Department of Neurosurgery, The National Hospital for Neurology and Neurosurgery, London, United Kingdom
    J Neurosurg Spine 7:594-600. 2007
    ..This study is a retrospective review of the 21-year experience of ventral decompression surgery and dorsal occipitocervical fixation in patients with BI secondary to OI and is the largest patient series reported to date...
  49. ncbi Three sisters with Chiari I malformation with and without associated syringomyelia
    James D Weisfeld-Adams
    Department of Paediatric Neurology and Neurosurgery, Frenchay Hospital, Bristol, UK
    Pediatr Neurosurg 43:533-8. 2007
    ..A fourth (the eldest) sister was asymptomatic and did not have CMI or syrinx. The girls' mother had platybasia on screening MR and a history of cough headaches...
  50. pmc C1-C2 arthrodesis after transoral odontoidectomy and suboccipital craniectomy for ventral brain stem compression in Chiari I patients
    Steven W Hwang
    Department of Neurosurgery 178, Tufts New England Medical Center, 750 Washington Street, Boston, MA 02111, USA
    Eur Spine J 17:1211-7. 2008
    Chiari I malformations are often associated with congenital craniocervical anomalies such as platybasia, basilar invagination, and retroflexion of the odontoid process...
  51. ncbi Atlantoaxial joint distraction as a treatment for basilar invagination: a report of an experience with 11 cases
    Atul Goel
    Department of Neurosurgery, King Edward 7th Memorial Hospital and Seth GS Medical College, Parel, Mumbai, Maharashtra, India
    Neurol India 56:144-50. 2008
    ..Bone graft that is additionally placed within the appropriately prepared atlantoaxial joint and posterior to the arch of atlas and lamina of C2 provides bony fusion...
  52. ncbi Posterior occipitocervical fixation under skull-femoral traction for the treatment of basilar impression in a child with Klippel-Feil syndrome
    T Dokai
    Department of Orthopedic Surgery, Faculty of Medicine, Tottori University, 36 1 Nishi cho, Yonago, Tottori 683 8504, Japan
    J Bone Joint Surg Br 93:1571-4. 2011
    ..Our surgical strategy was an alternative solution. Prior to a posterior cervical fixation, without decompression, skull traction was used to confirm that the deformity was reducible and effective in resolving associated myelopathy...
  53. pmc The importance of platybasia and the palatine line in patient selection for endonasal surgery of the craniocervical junction: a radiographic study of 12 patients
    Ivan H El-Sayed
    Department of Otolaryngology Head and Neck Surgery, University of California at San Francisco, San Francisco, California, USA
    World Neurosurg 76:183-8; discussion 74-8. 2011
    ..is performed to manage a variety of conditions, including basilar invagination, which can be associated with platybasia. We have noted that the anatomic changes of platybasia could affect the height of the odontoid over a line drawn ..
  54. ncbi Cerebral anomalies and Chiari type 1 malformation
    Marcelo Galarza
    Regional Service of Neurosurgery, Virgen de la Arrixaca University Hospital, Murcia, Spain
    Pediatr Neurosurg 46:442-9. 2010
    ..To analyze the association of diverse cerebral anomalies in a series of pediatric patients with cerebellar tonsillar ectopia...
  55. ncbi The role of cephalometry in assessing velopharyngeal dysfunction in velocardiofacial syndrome
    Aravindhan Veerapandiyan
    Duke University Medical Center, Division of Medical Genetics, Department of Pediatrics, Durham, North Carlolina 27710, USA
    Laryngoscope 121:732-7. 2011
    ..To report our experience with cephalometry in evaluating velopharyngeal dysfunction (VPD) in velocardiofacial syndrome (VCFS) and its utility in assessing the role of cervical spine abnormalities in VPD, prior to surgical correction of VPD...
  56. ncbi Cranial base, maxillary and mandibular morphology in Down syndrome
    Sunjay Suri
    Discipline of Orthodontics, Faculty of Dentistry, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
    Angle Orthod 80:861-9. 2010
    ..To test the null hypothesis that there is no difference between craniofacial measurements of individuals with Down syndrome (DS) and normal controls...
  57. ncbi Brain stem compression and atlantoaxial instability secondary to chronic rheumatoid arthritis in a 67-year-old female
    Eve E Bonic
    Department of Radiology, Logan College of Chiropractic, Chesterfield, Missouri 63006 1065, USA
    J Manipulative Physiol Ther 33:315-20. 2010
    ..The pathophysiology, clinical presentation, imaging, and surgical management are discussed...
  58. ncbi Posterior fossa arachnoid cysts and cerebellar tonsillar descent: short review
    Marcelo Galarza
    Regional Service of Neurosurgery, Virgen de la Arrixaca University Hospital, El Palmar, 30120 Murcia, Spain
    Neurosurg Rev 33:305-14; discussion 314. 2010
    ..A patient with achondroplasia showed features of platybasia. Associated malformations included craniofacial dysmorphism in a patient diagnosed of trichorhinophalangeal ..
  59. ncbi Dimensions of the craniocervical junction in longitudinal analysis of normal growth
    Heidi Arponen
    Department of Orthodontics, Institute of Dentistry, University of Helsinki, P O Box 41, 00014, Helsinki, Finland
    Childs Nerv Syst 26:763-9. 2010
    ..of the craniocervical junction in the form of basilar impression or invagination, with often-associated platybasia, is a clinically significant cause of neurological symptoms particularly in patients with inherited diseases ..
  60. pmc Syringomyelia with irreducible atlantoaxial dislocation, basilar invagination and Chiari I malformation
    Shenglin Wang
    Orthopaedic Department, Peking University Third Hospital, No 49 North Garden Street, Haidian District, 100191 Beijing, China
    Eur Spine J 19:361-6. 2010
    ..Final follow-up at 2-years revealed an excellent clinical outcome...
  61. ncbi Basilar invagination, Chiari malformation, syringomyelia: a review
    Atul Goel
    Department of Neurosurgery, KEM Hospital and Seth GS Medical College, Parel, Mumbai 400 012, India
    Neurol India 57:235-46. 2009
    ..The division of patients with basilar invagination on the basis of presence or absence of instability provides insight into the pathogenesis of the anomaly and a basis for rational surgical treatment...
  62. ncbi Endoscopic transnasal decompression for management of basilar invagination in osteogenesis imperfecta
    Mitchell A Hansen
    Department of Neurosurgery, Westmead Private Hospital, Westmead, Australia
    J Neurosurg Spine 9:354-7. 2008
    ..This technical note outlines a novel endoscopic transnasal approach for ventral decompression. The literature is reviewed and a strategy for the management of BI in patients with OI is outlined...
  63. ncbi Surgical planning for restoring velopharyngeal function in velocardiofacial syndrome
    Antonio Ysunza
    Cleft Palate Clinic, Hospital Gea Gonzalez, Mexico City, Mexico
    Int J Pediatr Otorhinolaryngol 73:1572-5. 2009
    ..VPI is much more frequent due to special abnormal conditions inherent to VCFS including: platybasia, hypotrophy of adenoid, enlarged tonsils, hypotonia and abnormal pharyngeal muscles.
  64. ncbi [A new surgical treatment for syringomyelia, scoliosis, Arnold-Chiari malformation, kinking of the brainstem, odontoid recess, idiopathic basilar impression and platybasia]
    M B Royo Salvador
    , , Barcelona, Jefe del,
    Rev Neurol 25:523-30. 1997
    ..responsible for idiopathic syringomyelia (SMI), idiopathic scoliosis (ESCID), Arnold Chiari malformation (ARCH), platybasia (PTB), basilar impression (IMB), odontoid recess (RTO) kinking of the brain stem (KTC) and considering the ..
  65. ncbi [Schwartz-Jampel syndrome: a description of two adult siblings]
    F J Carod-Artal
    Hospital Sarah, Brasilia DF, Brasil
    Rev Neurol 35:131-4. 2002
    ..We report on the clinical, electromyographical and radiological findings of two siblings affected by the disease and who were diagnosed late, in adulthood...
  66. ncbi Cranial settling
    David W Cahill
    J Neurosurg 97:272; author reply 272. 2002
  67. ncbi [Radiological changes in the cervical spine in rheumatoid arthritis -- prognostic factors obtained by a cross-sectional study]
    H Reichel
    Universitätsklinik und Poliklinik für Orthopädie und Physikalische Medizin, Martin Luther Universitat Halle Wittenberg, Magdeburger Str 22, 06097 Halle, Germany halle de
    Z Rheumatol 61:710-7. 2002
    ..The study investigates the relationship between the course of the RA and the degree of radiological changes in the cervical spine and describes prognostic factors of cervical spine involvement...
  68. ncbi Hajdu-Cheney syndrome and syringomyelia. Case report
    Alexis Faure
    Department of Neurotraumatology, University Hospital Hotel Dieu, Nantes, France
    J Neurosurg 97:1441-6. 2002
    ..7-year-old boy with Hajdu-Cheney syndrome presented with cervical syringomyelia related to rapidly progressing platybasia. Decompressive craniectomy provided temporary improvement, and his clinical status was eventually stabilized ..
  69. ncbi Resolution of syringomyelia and basilar invagination after traction. Case illustration
    Vivek Joseph
    Department of Neurological Sciences, Christian Medical College and Hospital, Vellore, Tamil Nadu, India
    J Neurosurg 98:298. 2003
  70. ncbi Osteogenesis imperfecta in childhood: MR imaging of basilar impression
    G J M Janus
    Department of Pediatric Orthopaedics, University Medical Centre, Wilhelmina Childrens Hospital, Utrecht, The Netherlands
    Eur J Radiol 47:19-24. 2003
    ..To confirm this sign and altered geometrical relationships of the craniocervical junction in course of time with magnetic resonance imaging (MRI)...
  71. ncbi Basilar impression, Chiari malformation and syringomyelia: a retrospective study of 53 surgically treated patients
    José Alberto Gonçalves da Silva
    Serviço de Neurologia e Neurocirurgia, Hospital Santa Isabel, João Pessoa PB, Brazil
    Arq Neuropsiquiatr 61:368-75. 2003
    ....
  72. ncbi Treatment of craniocervical spine lesion with osteogenesis imperfecta: a case report
    Masahiro Nakamura
    Department of Orthopaedic Surgery, Faculty of Medicine, Kagoshima University, Kagoshima, Japan
    Spine (Phila Pa 1976) 27:E224-7. 2002
    ..A case report of craniocervical spine lesions including basilar impression, atlantoaxial dislocation, and syringomyelia, with osteogenesis imperfecta is presented, and the literature is reviewed...
  73. ncbi [Arnold-Chiari II malformation and basilar impression. Report of one case (a literature review)]
    M Thiebaut
    Service de médecine physique et réadaptation fonctionnelle, Hopital Morvan, 5, avenue Foch, 29609, Brest, France
    Ann Readapt Med Phys 45:131-8. 2002
    ..To tell the rare association of Arnold-Chiari II malformation and basilar impression and to describe an exceptional clinical state with a particular surgical approach...
  74. ncbi Neurofibromatosis, stroke and basilar impression. Case report
    E J Piovesan
    Internal Medicine Department, Hospital de Clinicas of Federal University of Parana, Brasil
    Arq Neuropsiquiatr 57:484-8. 1999
    ..Basilar impression associated with this case may be considered a pure coincidence, but rare cases of basilar impression and NF1 have been described...
  75. ncbi Homonucleotide expansion and contraction mutations of PAX2 and inclusion of Chiari 1 malformation as part of renal-coloboma syndrome
    L A Schimmenti
    Departments of Human Genetics and Pediatrics, University of California, Los Angeles 90095 7088, USA
    Hum Mutat 14:369-76. 1999
    ..Additionally, this girl developed hydrocephalus associated with platybasia and a Chiari 1 malformation. We examined genomic DNA from these individuals by SSCP and sequencing...
  76. ncbi Velopharyngeal insufficiency and articulation impairment in velo-cardio-facial syndrome: the influence of adenoids on phonemic development
    N Havkin
    Communication Disorder Unit, Center for the Diagnosis, Treatment, and Study of Velo Cardio Facial Syndrome, Department of Otolaryngology and Communication Science, Upstate Medical University, Syracuse, NY 13210, USA
    Int J Pediatr Otorhinolaryngol 54:103-10. 2000
    ..Factors studied included palatal clefting, hypotonia, platybasia, and adenoid size...
  77. ncbi Stroke following appendectomy under general anesthesia in a patient with basilar impression
    H Zotter
    Department of Pediatrics, University of Graz, Austria
    Acta Anaesthesiol Scand 44:1271-2. 2000
    ....
  78. ncbi Diagnosing basilar invagination in the rheumatoid patient. The reliability of radiographic criteria
    K D Riew
    The University Hospitals Spine Institute, Cleveland, Ohio 44106, USA
    J Bone Joint Surg Am 83:194-200. 2001
    ..The purpose of the present study was to validate and compare the most widely accepted plain radiographic criteria for basilar invagination in this patient population...
  79. ncbi Osteogenesis imperfecta at the beginning of bone and joint decade
    D Primorac
    Laboratory for Clinical and Forensic Genetics, Split University Hospital and School of Medicine, Spinciceva 1, 21 000 Split, Croatia
    Croat Med J 42:393-415. 2001
    ..Thus, we also describe different genetic therapeutic approaches that have been tested either on OI cells or on available OI murine models...
  80. ncbi Trigeminal neuralgia associated with achondroplasia. Case report with literature review
    Y Takada
    Department of Neurosurgery, Tokyo Medical and Dental University, Tokyo, Japan
    Acta Neurochir (Wien) 143:1173-6. 2001
    ..This is the first reported case of trigeminal neuralgia in a patient with achondroplasia. The deformity of the skull base was considered to influence the development of the trigeminal neuralgia...
  81. ncbi Extreme lateral-transatlas approach for resection of the dens of the axis
    Ugur Ture
    Department of Neurosurgery, Marmara University School of Medicine, Istanbul, Turkey
    J Neurosurg 96:73-82. 2002
    ..as an alternative approach. In this report, the authors describe the surgical technique of the extreme lateral-transatlas approach and their clinical experiences...
  82. ncbi [Anterior bulbar compresion with basilar impresion. Surgical management by 2-Piece Le Fort I Transmaxilar Osteotomy]
    F Falahat
    Servicios de Cirugia Oral y macilofacial, Hospital Clínico San Carlos Madrid Spain
    Neurocirugia (Astur) 14:417-22. 2003
    ..Therefore we chose the use of a LFPS to approach this lesion. With an optimal surgical field, a complete excision of the lesion was obtained. The postoperatory result in the subsequent follow-up was highly satisfactory...
  83. ncbi A prospective controlled study of sleep respiratory events in patients with craniovertebral junction malformation
    Ricardo Vieira Botelho
    Department of Psychobiology, Sleep Institute, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    J Neurosurg 99:1004-9. 2003
    ..The respiratory center and some of its afferent and efferent components can be altered in these diseases. The authors studied patients with and without CVJM to determine whether this physical feature contributed to sleep disturbances...
  84. ncbi Circumferential decompression of the foramen magnum for the treatment of syringomyelia associated with basilar invagination
    Frederic P Collignon
    Department of Neurologic Surgery, Joseph 1 229, Saint Mary s Hospital, Mayo Clinic and Mayo Foundation, MN 55905, Rochester, USA
    Neurosurg Rev 27:168-72. 2004
    ..These cases demonstrate that circumferential decompression of the foramen magnum may be necessary in some cases of cervical syringomyelia associated with basilar invagination and Chiari malformation...
  85. ncbi Midfacial translocation, a variation of the approach to the rhinopharynx, clivus and upper odontoid process
    Francisco Verissimo de Mello-Filho
    Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, University Hospital, Faculty of Medicine of Ribeirao Preto, University of Sao Paulo, Brazil
    J Craniomaxillofac Surg 34:400-4. 2006
    ....
  86. ncbi Basilar impression in osteogenesis imperfecta: can it be treated with halo traction and posterior fusion?
    D P Noske
    Department of Neurosurgery, VU University Medical Center, Amsterdam, The Netherlands
    Acta Neurochir (Wien) 148:1301-5; discussion 1305. 2006
    ..In conclusion, posterior fusion without additional VP shunt placement may not be effective in the long term for ameliorating symptoms and signs and halting progressive hydrocephalus in BI complicating OI...
  87. ncbi Endoscopic transoral surgery for craniovertebral junction anomalies. Technical note
    Mazhar Husain
    Department of Neurosurgery, King George s Medical University, Lucknow, India
    J Neurosurg Spine 5:367-73. 2006
    ..The use of minimally invasive endoscopic techniques has the potential to reduce the need for a wider cranial base opening and to decrease postoperative complications...
  88. ncbi Evaluation of platybasia in patients with idiopathic trigeminal neuralgia
    Yucel Kanpolat
    Department of Neurosurgery, School of Medicine, Ankara University, Ankara 06100, Turkey
    Surg Neurol 67:78-81; discussion 81-2. 2007
    ..The aim of the present study was to investigate one such skull base deformity, platybasia, in ITN patients in comparison with a randomized control population.
  89. ncbi Endoscopic image-guided odontoidectomy for decompression of basilar invagination via a standard anterior cervical approach. Technical note
    Jean Paul Wolinsky
    Department of Neurosurgery, Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    J Neurosurg Spine 6:184-91. 2007
    ..The technique is safe and effective for decompression and provides a surgical route that can be added to the armamentarium of treatments for pathological conditions in this region...
  90. ncbi Platybasia and basilar invagination
    J M S Pearce
    Department of Neurology, Hull Royal Infirmary and Hull York Medical School, Hull, UK
    Eur Neurol 58:62-4. 2007
    Descriptions of the flattening (platybasia) of the skull base and the upward displacement(impression) of the basilar and condylar portions of the occipitalbone by the upper cervical spine date to the late 18th and early 19th centuries...
  91. ncbi Congenital anomalies of the cervical spine
    Paul Klimo
    88th SGOS SGCXN, Wright Patterson Air Force Base, OH 45433, USA
    Neurosurg Clin N Am 18:463-78. 2007
    ..In general, those lesions that are causing or have caused neurologic injury, chronic pain, or spinal deformity or place the patient at high risk for developing these require treatment...
  92. ncbi [Surgical therapy of the rheumatic cervical spine]
    F Kerschbaumer
    Klinik Rotes Kreuz, Frankfurt am Main
    Z Orthop Unfall 145:655-69; quiz 670-3. 2007
  93. ncbi Skull base abnormalities in osteogenesis imperfecta: a cephalometric evaluation of 54 patients and 108 control volunteers
    Outi Kovero
    Department of Oral Radiology, Institute of Dentistry, University of Helsinki, Finland
    J Neurosurg 105:361-70. 2006
    ..They were surprised to find that the previously used diagnostic measures for basilar abnormality in patients with OI were exceeded in 6.5 to 7.4% of the controls, and hence needed to be reevaluated...
  94. ncbi Halo traction in basilar invagination: technical case report
    Serkan Simsek
    Neurosurgery Department, Ministry of Health, Diskapi Educational and Research Hospital, Ankara 06110, Turkey
    Surg Neurol 66:311-4; discussion 314. 2006
    ..We aimed to discuss the role of the halo vest apparatus traction on the reduction of severe anterior compression pathologies in basilar invagination...
  95. ncbi Myelopathy by lesions of the craniocervical junction in a patient with forestier disease
    Hugues Pascal-Moussellard
    Service Orthopédie Pr Saillant, CHU Pitie Salpetriere, Paris, France
    Spine (Phila Pa 1976) 31:E557-60. 2006
    ..The authors report a case of a patient with diffuse idiopathic skeletal hyperostosis (DISH) associated with basilar impression resulting in tetraparesis...
  96. ncbi Surgical management of high cervical disc prolapse associated with basilar invagination--two case reports
    Atul Goel
    Department of Neurosurgery, Seth G S Medical College and King Edward Memorial Hospital, Parel, Mumbai, India
    Neurol Med Chir (Tokyo) 44:142-5. 2004
    ..Both the patients were relieved of symptoms and remained asymptomatic at follow up. Simultaneous fixation procedure is not mandatory after transoral surgery in patients with basilar invagination...
  97. ncbi [A case of brainstem and cerebellar infarctions related to basilar impression]
    Takashi Kasai
    Department of Neurology, Kyoto Prefectural University of Medicine
    Rinsho Shinkeigaku 44:203-6. 2004
    ..The mechanical stress on the bilateral vertebral arteries may have caused infarctions in the territories of the posterior circulation of this patient with basilar impression...
  98. ncbi Results of the treatment of syringomyelia associated with Chiari malformation: analysis of 60 cases
    José Arnaldo Motta de Arruda
    Servico de Neurologia, Hospital Universitario Walter Cantidio, Universidade Federal do Ceara, Fortaleza, CE, Brasil
    Arq Neuropsiquiatr 62:237-44. 2004
    ..Syringomyelia signs improved statistically more than CM signs. In half of patients, the percent improvement of signs and symptoms ranged between 40% and 60%...
  99. ncbi Malformations of the craniocervical junction: 3D-CT evaluation
    I Tsitouridis
    Radiology Dept, Papageorgiou General Hospital, Thessaloniki, Greece
    Stud Health Technol Inform 91:320-1. 2002
  100. ncbi Progressive basilar invagination after transoral odontoidectomy: treatment by atlantoaxial facet distraction and craniovertebral realignment
    Atul Goel
    Department of Neurosurgery, King Edward Memorial Hospital, Seth G S Medical College, Mumbai, India
    Spine (Phila Pa 1976) 30:E551-5. 2005
    ....
  101. ncbi Craniovertebral junction realignment for the treatment of basilar invagination with syringomyelia: preliminary report of 12 cases
    Atul Goel
    Department of Neurosurgery, King Edward Memorial Hospital, Parel, Mumbai, India
    Neurol Med Chir (Tokyo) 45:512-7; discussion 518. 2005
    ..Manipulation of the atlantoaxial joints and restoring the anatomical craniovertebral alignments in selected cases of syringomyelia leads to remarkable and sustained clinical recovery, and is probably the optimum surgical treatment...

Research Grants1

  1. HDAd-mediated gene therapy for hemophilia B
    Nicola Brunetti Pierri; Fiscal Year: 2008
    ..unreadable] [unreadable]..