presbyopia

Summary

Summary: The normal decreasing elasticity of the crystalline lens that leads to loss of accommodation.

Top Publications

  1. ncbi The NuLens accommodating intraocular lens
    Joshua Ben-nun
    NuLens Ltd, 15 Maskit Street, Herzliya Pituach, Israel 972 9 9549495
    Ophthalmol Clin North Am 19:129-34, vii. 2006
  2. ncbi Reading performance after implantation of a small-aperture corneal inlay for the surgical correction of presbyopia: Two-year follow-up
    Alois K Dexl
    University Eye Clinic, Paracelsus Medical University, Salzburg, Austria
    J Cataract Refract Surg 37:525-31. 2011
  3. ncbi Intracorneal inlay to correct presbyopia: Long-term results
    Omer F Yilmaz
    Beyoglu Eye Training and Research Hospital, Istanbul, Turkey
    J Cataract Refract Surg 37:1275-81. 2011
  4. ncbi [Accommodative intraocular lenses--principles of clinical evaluation and current results]
    O K Klaproth
    Klinik fur Augenheilkunde, Goethe Universitat Frankfurt am Main, Theodor Stern Kai 7, Frankfurt am Main
    Klin Monbl Augenheilkd 228:666-75. 2011
  5. ncbi One-year visual outcomes and patient satisfaction after surgical correction of presbyopia with an intracorneal inlay of a new design
    Alois K Dexl
    University Eye Clinic, Paracelsus Medical University, Salzburg, Austria
    J Cataract Refract Surg 38:262-9. 2012
  6. ncbi Correction of presbyopia with a small aperture corneal inlay
    George O Waring
    Revision Advanced Laser Eye Center, Columbus, Ohio 43240, USA
    J Refract Surg 27:842-5. 2011
  7. ncbi Intracorneal inlay for the surgical correction of presbyopia
    Omer F Yilmaz
    Beyoglu Eye Research and Education Hospital, Istanbul, Turkey
    J Cataract Refract Surg 34:1921-7. 2008
  8. ncbi Central and peripheral corneal iron deposits after implantation of a small-aperture corneal inlay for correction of presbyopia
    Alois K Dexl
    University Eye Clinic, Paracelus Medical University, Salzburg, Austria, Germany
    J Refract Surg 27:876-80. 2011
  9. ncbi Optical modeling of a corneal inlay in real eyes to increase depth of focus: optimum centration and residual defocus
    Juan Tabernero
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
    J Cataract Refract Surg 38:270-7. 2012
  10. ncbi Presbyopia: the first stage of nuclear cataract?
    S J McGinty
    Save Sight Institute, Sydney, and Institute for Biomolecular Science, University of Wollongong, Wollongong, Australia
    Ophthalmic Res 38:137-48. 2006

Research Grants

  1. Adjustable Injectable Intraocular Lens
    Shiao Chang; Fiscal Year: 2007
  2. Development Of An Eye Drop To Treat Presbyopia
    William H Garner; Fiscal Year: 2012
  3. Mechanisms of lens growth regulation
    Xiaohua Gong; Fiscal Year: 2013
  4. MRI Biometry of the Pseudophakic Cadaver Eye
    Susan A Strenk; Fiscal Year: 2010
  5. In Vivo Evaluation of Presbyopia
    Kathryn Richdale; Fiscal Year: 2013
  6. A DATABASE OF IOL POSITION AND BEHAVIOR
    Susan A Strenk; Fiscal Year: 2010
  7. ACCOMMODATIVE CONTACT LENs FOR PRESBYOPIC CORRECTION
    Hongrui Jiang; Fiscal Year: 2011
  8. Optical coherence tomography equipped wavefront system for studying accommodation
    Ji chang He; Fiscal Year: 2013
  9. Electro-optic adaptive eyeglass for correction of presbyopia
    Guoqiang Li; Fiscal Year: 2013
  10. Curvature Changing Accommodating IOL
    James T Schwiegerling; Fiscal Year: 2012

Detail Information

Publications251 found, 100 shown here

  1. ncbi The NuLens accommodating intraocular lens
    Joshua Ben-nun
    NuLens Ltd, 15 Maskit Street, Herzliya Pituach, Israel 972 9 9549495
    Ophthalmol Clin North Am 19:129-34, vii. 2006
    ..Basic study of the concept of optomechanics in the primate eye led to successful construction and implantation of functioning IOL prototypes...
  2. ncbi Reading performance after implantation of a small-aperture corneal inlay for the surgical correction of presbyopia: Two-year follow-up
    Alois K Dexl
    University Eye Clinic, Paracelsus Medical University, Salzburg, Austria
    J Cataract Refract Surg 37:525-31. 2011
    ..To evaluate the change in reading-performance parameters after implantation of the Kamra small-aperture intracorneal inlay over a 2-year follow-up...
  3. ncbi Intracorneal inlay to correct presbyopia: Long-term results
    Omer F Yilmaz
    Beyoglu Eye Training and Research Hospital, Istanbul, Turkey
    J Cataract Refract Surg 37:1275-81. 2011
    ..To evaluate the long-term visual results of Acufocus ACI-7000 (now Kamra) intracorneal inlay implantation in presbyopic phakic patients...
  4. ncbi [Accommodative intraocular lenses--principles of clinical evaluation and current results]
    O K Klaproth
    Klinik fur Augenheilkunde, Goethe Universitat Frankfurt am Main, Theodor Stern Kai 7, Frankfurt am Main
    Klin Monbl Augenheilkd 228:666-75. 2011
    A potential option for the correction of presbyopia after cataract extraction or refractive lens exchange is the implantation of accommodative intraocular lenses (IOL)...
  5. ncbi One-year visual outcomes and patient satisfaction after surgical correction of presbyopia with an intracorneal inlay of a new design
    Alois K Dexl
    University Eye Clinic, Paracelsus Medical University, Salzburg, Austria
    J Cataract Refract Surg 38:262-9. 2012
    ..To evaluate the safety and efficacy of the third-generation Kamra corneal inlay (ACI 7000PDT) implanted monocularly in corneal pockets of emmetropic presbyopic patients to improve near and intermediate vision...
  6. ncbi Correction of presbyopia with a small aperture corneal inlay
    George O Waring
    Revision Advanced Laser Eye Center, Columbus, Ohio 43240, USA
    J Refract Surg 27:842-5. 2011
    ..To assess the efficacy of a small aperture corneal inlay (KAMRA, AcuFocus Inc) to improve near vision in emmetropic presbyopes...
  7. ncbi Intracorneal inlay for the surgical correction of presbyopia
    Omer F Yilmaz
    Beyoglu Eye Research and Education Hospital, Istanbul, Turkey
    J Cataract Refract Surg 34:1921-7. 2008
    ..To evaluate the clinical safety and efficacy of the ACI-7000 intracorneal inlay in increasing the depth of field in emmetropic presbyopic patients...
  8. ncbi Central and peripheral corneal iron deposits after implantation of a small-aperture corneal inlay for correction of presbyopia
    Alois K Dexl
    University Eye Clinic, Paracelus Medical University, Salzburg, Austria, Germany
    J Refract Surg 27:876-80. 2011
    To describe central and peripheral corneal iron deposition after implantation of the AcuFocus corneal inlay (ACI 7000, AcuFocus Inc) for the surgical correction of presbyopia.
  9. ncbi Optical modeling of a corneal inlay in real eyes to increase depth of focus: optimum centration and residual defocus
    Juan Tabernero
    Laboratorio de Optica, Universidad de Murcia, Murcia, Spain
    J Cataract Refract Surg 38:270-7. 2012
    ..To determine the optimum position to center a small-aperture corneal inlay and the effect of residual defocus in the surgical eye to maximize depth of focus...
  10. ncbi Presbyopia: the first stage of nuclear cataract?
    S J McGinty
    Save Sight Institute, Sydney, and Institute for Biomolecular Science, University of Wollongong, Wollongong, Australia
    Ophthalmic Res 38:137-48. 2006
    b>Presbyopia, the inability to accommodate, affects almost everyone at middle age...
  11. ncbi In vitro dimensions and curvatures of human lenses
    Alexandre M Rosen
    Ophthalmic Biophysics Center, Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, FL, USA
    Vision Res 46:1002-9. 2006
    ..Together, these observations provide additional support for the Helmholtz theory of accommodation...
  12. ncbi Presbyopic spectacle coverage, willingness to pay for near correction, and the impact of correcting uncorrected presbyopia in adults in Zanzibar, East Africa
    Heidi R Laviers
    International Centre for Eye Health, London School of Hygiene and Tropical Medicine, London, United Kingdom
    Invest Ophthalmol Vis Sci 51:1234-41. 2010
    To assess presbyopic spectacle coverage, willingness to pay, and the impact of correcting uncorrected presbyopia in individuals 40 years of age and older in Zanzibar and whether assessment of presbyopia can be incorporated into Rapid ..
  13. ncbi Presbyopia and the optical changes in the human crystalline lens with age
    A Glasser
    School of Optometry, University of Waterloo, Ontario, Canada
    Vision Res 38:209-29. 1998
    ..These data provide additional evidence for predominantly lens-based theories of presbyopia. Further, these results show that there are substantial optical changes in the human lens with increasing age ..
  14. ncbi Short-term cell death and inflammation after intracorneal inlay implantation in rabbits
    Marcony R Santhiago
    The Cole Eye Institute, The Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Refract Surg 28:144-9. 2012
    To investigate the cell death and inflammatory response to insertion of the KAMRA inlay (AcuFocus Inc) for presbyopia.
  15. ncbi Refractive surgical correction of presbyopia with the AcuFocus small aperture corneal inlay: two-year follow-up
    Orang Seyeddain
    University Eye Clinic, Paracelsus Medical University, Müllner Hauptstraße 48, A 5020 Salzburg, Austria
    J Refract Surg 26:707-15. 2010
    ..To evaluate the safety and efficacy of the AcuFocus Corneal Inlay 7000 (ACI 7000) implanted in emmetropic presbyopic patients for the improvement of near and intermediate vision over 2-year follow-up...
  16. ncbi Intraocular lenses for presbyopia correction: past, present, and future
    Alejandro Lichtinger
    Department of Ophthalmology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
    Curr Opin Ophthalmol 23:40-6. 2012
    To discuss the development of presbyopia-correcting intraocular lenses (IOLs), what we have learned since their introduction a few decades ago, what are the options currently on the market, and where the technology is heading in the future...
  17. ncbi Small-aperture corneal inlay for the correction of presbyopia: 3-year follow-up
    Orang Seyeddain
    University Eye Clinic, Paracelsus Medical University, Salzburg, Austria
    J Cataract Refract Surg 38:35-45. 2012
    ..To report the 3-year postoperative safety and efficacy outcomes of the Acufocus corneal inlay...
  18. ncbi Femtosecond laser-assisted corneal pocket creation using a mask for inlay implantation
    Dimitrios I Bouzoukis
    Institute of Vision and Optics, University of Crete, Greece
    J Refract Surg 27:818-20. 2011
    ..the technique of femtosecond laser-assisted intracorneal pocket creation, using a mask for the implantation of a corneal inlay in the non-dominant eye of a 56-year-old, emmetropic, presbyopic woman for the correction of presbyopia.
  19. ncbi Refractive error and presbyopia among adults in Fiji
    Garry Brian
    The Fred Hollows Foundation New Zealand, Auckland, New Zealand
    Ophthalmic Epidemiol 18:75-82. 2011
    To characterize refractive error, presbyopia and their correction among adults aged ≥ 40 years in Fiji, and contribute to a regional overview of these conditions.
  20. ncbi Visual outcomes and safety of a refractive corneal inlay for presbyopia using femtosecond laser
    Aliki N Limnopoulou
    Department of Opthalmology, Vardinoyannion Eye Institute of Crete, Crete, Greece
    J Refract Surg 29:12-8. 2013
    To evaluate the outcomes and safety of a refractive inlay (Flexivue Micro-Lens, Presbia Coöperatief U.A.) for the corneal compensation of presbyopia.
  21. ncbi Correction of presbyopia by technovision central multifocal LASIK (presbyLASIK)
    Jorge L Alio
    Ophthalmology Department, Miguel Hernandez University, Alicante, Spain
    J Refract Surg 22:453-60. 2006
    ..To investigate central multifocal presbyLASIK based on the creation of a central hyperpositive area...
  22. ncbi The mechanism of accommodation and presbyopia
    Ronald A Schachar
    Department of Physics, University of Texas at Arlington, PO Box 601149, Dallas, TX 75360, USA
    Int Ophthalmol Clin 46:39-61. 2006
  23. ncbi One-year safety and efficacy results of a hydrogel inlay to improve near vision in patients with emmetropic presbyopia
    Enrique Barragan Garza
    Laser Ocular hidalgo, Nuevo Leone, Mexico
    J Refract Surg 29:166-72. 2013
    To conduct a feasibility study of the safety and efficacy of a corneal contouring inlay as a treatment for emmetropic presbyopia.
  24. ncbi [Effect of intrastromal correction of presbyopia with femtosecond laser (INTRACOR) on mesopic contrast sensitivity]
    A Fitting
    International Vision Correction Research Centre, Universitäts Augenklinik Heidelberg
    Ophthalmologe 109:1001-7. 2012
    The aim of this study was to examine the mesopic contrast sensitivity (CS) and glare sensitivity following intrastromal femtosecond laser correction of presbyopia (INTRACOR).
  25. ncbi Monovision outcomes in presbyopic individuals after refractive surgery
    S Jain
    Corneal and Refractive Surgery Service, Massachusetts Eye and Ear Infirmary, The Schepens Eye Research Institute, and Harvard Medical School, Boston, Massachusetts 02114, USA
    Ophthalmology 108:1430-3. 2001
    ..CONCLUSIONS: Monovision may be a valuable option for presbyopic individuals considering refractive surgery. Crossed monovision can result in satisfactory visual outcomes...
  26. ncbi Functional presbyopia in a rural Kenyan population: the unmet presbyopic need
    Justin C Sherwin
    Centre for Eye Research Australia, University of Melbourne, Melbourne, Australia
    Clin Experiment Ophthalmol 36:245-51. 2008
    b>Presbyopia is the most common reason for requiring spectacles in low-income regions, although the unmet need for presbyopic spectacles in these regions is very high...
  27. pmc An improved spinning lens test to determine the stiffness of the human lens
    H J Burd
    Department of Engineering Science, University of Oxford, Parks Road, Oxford, OX1 3PJ, UK
    Exp Eye Res 92:28-39. 2011
    It is widely accepted that age-related changes in lens stiffness are significant for the development of presbyopia. However, precise details on the relative importance of age-related changes in the stiffness of the lens, in comparison ..
  28. ncbi Intrastromal correction of presbyopia using a femtosecond laser system
    Luis Antonio Ruiz
    Centro Oftalmológico Colombiano, Bogota, Colombia
    J Refract Surg 25:847-54. 2009
    To introduce a new, minimally invasive intrastromal correction for presbyopia (INTRACOR procedure) using the TECHNOLAS femtosecond laser system (Technolas Perfect Vision GmbH).
  29. ncbi Early outcomes of INTRACOR femtosecond laser treatment for presbyopia
    Mike P Holzer
    University of Heidelberg, Department of Ophthalmology, International Vision Correction Research Centre, Germany
    J Refract Surg 25:855-61. 2009
    To investigate early functional outcomes of the INTRACOR femtosecond laser-based intrastromal procedure to treat presbyopia.
  30. ncbi Presbyopia. Emerging from a blur towards an understanding of the molecular basis for this most common eye condition
    Roger John Truscott
    Save Sight Institute, University of Sydney, NSW 2001, Australia
    Exp Eye Res 88:241-7. 2009
    ..Understanding such processes may allow us to glimpse the origin both of presbyopia and age-related nuclear cataract.
  31. ncbi Prevalence of uncorrected refractive errors, presbyopia and spectacle coverage in marine fishing communities in South India: Rapid Assessment of Visual Impairment (RAVI) project
    Srinivas Marmamula
    Allen Foster Community Eye Health Research Centre, L V Prasad Eye Institute, Hyderabad Bausch, India
    Ophthalmic Physiol Opt 32:149-55. 2012
    To investigate the prevalence of uncorrected refractive errors, presbyopia and spectacle coverage in subjects aged 40 years or more using a novel Rapid Assessment of Visual Impairment (RAVI) methodology.
  32. pmc Restoration of accommodation: surgical options for correction of presbyopia
    Adrian Glasser
    College of Optometry, University of Houston, Houston, TX 77204, USA
    Clin Exp Optom 91:279-95. 2008
    ..b>Presbyopia, the gradual age-related loss of accommodation, occurs primarily through a gradual age-related stiffening of the ..
  33. ncbi Impact of presbyopia on quality of life in a rural African setting
    Ilesh Patel
    Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, Maryland, USA
    Ophthalmology 113:728-34. 2006
    To determine the impact of uncorrected presbyopia on quality of life in rural Tanzania.
  34. ncbi Uncorrected refractive errors, presbyopia and spectacle coverage: results from a rapid assessment of refractive error survey
    Srinivas Marmamula
    L V Prasad Eye Institute, Banjara Hills, Hyderabad 500 034, India
    Ophthalmic Epidemiol 16:269-74. 2009
    To investigate the prevalence of uncorrected refractive errors, presbyopia and spectacle coverage in subjects aged 15-50 years using rapid assessment methodology in the Mahabubnagar district of Andhra Pradesh, India.
  35. ncbi Making perceptual learning practical to improve visual functions
    Uri Polat
    Goldschleger Eye Research Institute, Tel Aviv University, Sheba Medical Center, Ramat Gan, 52621 Tel Hashomer, Israel
    Vision Res 49:2566-73. 2009
    ..learning method that previously used (amblyopia, myopia) and a novel technique and results that were applied for presbyopia. In general, subjects were trained for contrast detection of Gabor targets under lateral masking conditions...
  36. ncbi Presbyopia and cataract: a question of heat and time
    Roger J W Truscott
    Save Sight Institute, University of Sydney, NSW, Australia
    Prog Retin Eye Res 29:487-99. 2010
    ..Secondly, it will be extremely challenging to examine the origin of human age-related conditions, such as presbyopia and nuclear cataract, using traditional laboratory animals...
  37. ncbi Monovision: a review
    Bruce J W Evans
    Neville Chappell Research Clinic, Institute of Optometry, 56 62 Newington Causeway, London SE1 6DS, UK
    Ophthalmic Physiol Opt 27:417-39. 2007
    In presbyopia, patients can no longer obtain clear vision at distance and near. Monovision is a method of correcting presbyopia where one eye is focussed for distance vision and the other for near...
  38. ncbi The eye in focus: accommodation and presbyopia
    W Neil Charman
    Faculty of Life Sciences, University of Manchester, Sackville Street, Manchester, United Kingdom
    Clin Exp Optom 91:207-25. 2008
    ..Other factors may also contribute in an, as yet, unquantified way and a full understanding of the origins of presbyopic change remains elusive...
  39. ncbi Presbyopia and heat: changes associated with aging of the human lens suggest a functional role for the small heat shock protein, alpha-crystallin, in maintaining lens flexibility
    Karl R Heys
    Save Sight Institute, University of Sydney, Sydney, NSW 2001, Australia
    Aging Cell 6:807-15. 2007
    b>Presbyopia, the inability to focus up close, affects everyone by age 50 and is the most common eye condition. It is thought to result from changes to the lens over time making it less flexible...
  40. ncbi Neuroadaptation of presbyopia-correcting intraocular lenses
    Susan M Pepin
    Dartmouth Medical School, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Curr Opin Ophthalmol 19:10-2. 2008
    ..Technology is only improving these options for presbyopic-correcting intraocular lenses. Surgeons must consider the possible neuroadaptation abilities in patients that may help in the success of using these lenses...
  41. ncbi Global vision impairment due to uncorrected presbyopia
    Brien A Holden
    International Centre for Eyecare Education, The University of New South Wales, Sydney, NSW, Australia
    Arch Ophthalmol 126:1731-9. 2008
    To evaluate the personal and community burdens of uncorrected presbyopia.
  42. pmc Correction of refractive error and presbyopia in Timor-Leste
    J Ramke
    The International Centre for Eyecare Education, Sydney, New South Wales, Australia
    Br J Ophthalmol 91:860-6. 2007
    To investigate the aspects of spectacle correction of vision-impairing refractive error and presbyopia in those aged >or=40 years in Timor-Leste.
  43. ncbi Biometric, optical and physical changes in the isolated human crystalline lens with age in relation to presbyopia
    A Glasser
    College of Optometry, University of Houston, TX 77204, USA
    Vision Res 39:1991-2015. 1999
    ..reinforce the conclusion that lens hardening must be considered as an important factor in the development of presbyopia, that age changes in the human lens are not limited to the loss of accommodation that characterizes presbyopia ..
  44. ncbi A population-based assessment of presbyopia in the state of Andhra Pradesh, south India: the Andhra Pradesh Eye Disease Study
    Praveen K Nirmalan
    International Center for Advancement of Rural Eye Care, L V Prasad Eye Institute, Hyderabad, India
    Invest Ophthalmol Vis Sci 47:2324-8. 2006
    To determine the prevalence of presbyopia in the state of Andhra Pradesh in south India.
  45. ncbi Femtosecond laser induced flexibility change of human donor lenses
    Silvia Schumacher
    Laser Zentrum Hannover e V, Hollerithallee 8, 30419 Hanover, Germany
    Vision Res 49:1853-9. 2009
    ..A permanent treatment method for presbyopia which offers a dynamic accommodation ability is a recent field of study...
  46. ncbi [Light adjustable lens. New options for customized correction of presbyopia]
    F H Hengerer
    Universitats Augenklinik, Knappschaftskrankenhaus, Ruhr Universitat Bochum, In der Schornau 23 25, 44892, Bochum, Deutschland
    Ophthalmologe 109:676-82. 2012
    The aim of this study was a prospective evaluation of new algorithms for the treatment of presbyopia using a light-adjustable intraocular lens (LAL).
  47. ncbi Distance and near visual acuity improvement after implantation of multifocal intraocular lenses in cataract patients with presbyopia: a systematic review
    Blaise Agresta
    Health Economics and Outcomes Research, IMS Health, London, UK
    J Refract Surg 28:426-35. 2012
    ....
  48. ncbi Multifocal intraocular lens implantation in prepresbyopic patients with unilateral cataract
    Philipp C Jacobi
    Department of Ophthalmology, University of Cologne, Joseph Stelzmannstrasse 9, 50931 Cologne, Germany
    Ophthalmology 109:680-6. 2002
    ..To evaluate the benefits of implantation of a zonal-progressive multifocal intraocular lens (IOL) in prepresbyopic patients with unilateral cataract...
  49. ncbi Impact of corneal aberrations on through-focus image quality of presbyopia-correcting intraocular lenses using an adaptive optics bench system
    Len Zheleznyak
    Flaum Eye Institute, University of Rochester, Rochester, NY 14624, USA
    J Cataract Refract Surg 38:1724-33. 2012
    To measure the impact of corneal aberrations on the through-focus image quality of presbyopia-correcting intraocular lenses (IOLs) using an adaptive optics IOL metrology system.
  50. ncbi Reading performance and patient satisfaction after corneal inlay implantation for presbyopia correction: two-year follow-up
    Alois K Dexl
    Department of Ophthalmology, Paracelsus Medical University, Salzburg, Austria
    J Cataract Refract Surg 38:1808-16. 2012
    To evaluate change in reading performance parameters after monocular Kamra corneal inlay implantation for the surgical correction of presbyopia.
  51. ncbi Corneal approach to hyperopic presbyopia treatment: six-month outcomes of a new multifocal excimer laser in situ keratomileusis procedure
    Andrea Ryan
    Department of Refractive Surgery, Mater Private Hospital, Dublin, Ireland
    J Cataract Refract Surg 39:1226-33. 2013
    To report the safety and efficacy of treatment of hyperopic presbyopia with a new multifocal corneal laser in situ keratomileusis (LASIK) procedure, Supracor.
  52. pmc Comparing the rate of regression after conductive keratoplasty with or without prior laser-assisted in situ keratomileusis or photorefractive keratectomy
    Majid Moshirfar
    Department of Ophthalmology and Visual Sciences, University of Utah, John A Moran Eye Center, Salt Lake City, UT, USA
    Middle East Afr J Ophthalmol 19:377-81. 2012
    ..To assess the regression rate of conductive keratoplasty (CK) in patients with or without previous laser-assisted in situ keratomileusis (LASIK) or photorefractive keratectomy (PRK)...
  53. ncbi Small-aperture corneal inlay implantation to treat presbyopia after laser in situ keratomileusis
    Minoru Tomita
    Shinagawa LASIK Center, Tokyo, Japan
    J Cataract Refract Surg 39:898-905. 2013
    To evaluate the visual outcomes after implantation of a Kamra small-aperture corneal inlay into a femtosecond-created corneal pocket to treat presbyopia in patients who had previous laser in situ keratomileusis (LASIK).
  54. ncbi Keratectasia after treating presbyopia with INTRACOR followed by SUPRACOR enhancement
    Suphi Taneri
    Eye Department, St Francis Hospital, Muenster, Germany
    J Refract Surg 29:573-6. 2013
    To report a case of unilateral keratectasia after INTRACOR, which was followed by an additional excimer LASIK enhancement with a new presbyopia-correcting ablation profile.
  55. ncbi Femtosecond laser correction of presbyopia (INTRACOR) in emmetropes using a modified pattern
    Bettina C Thomas
    International Vision Corection Research Centre, Department of Ophthalmology, University of Heidelberg, Germany
    J Refract Surg 28:872-8. 2012
    To evaluate functional results and corneal changes after femtosecond laser correction of presbyopia (INTRACOR, Technolas Perfect Vision GmbH) in emmetropes using a modified treatment pattern over a 12-month period.
  56. ncbi LASIK in the presbyopic age group: safety, efficacy, and predictability in 40- to 69-year-old patients
    Ramon C Ghanem
    Department of Ophthalmology, Massachusetts Eye and Ear Infirmary and Schepens Eye Research Institute, Harvard Medical School, Boston, Massachusetts, USA
    Ophthalmology 114:1303-10. 2007
    ..To report the safety, efficacy, and predictability of LASIK in a presbyopic population and to examine possible differences between age groups...
  57. ncbi Ocular integrity after anterior ciliary sclerotomy and scleral ablation by the Er:YAG laser
    Mitsutoshi Ito
    Minamiaoyama Eye Clinic, 2 27 25 Minamiaoyama, Minato ku, Tokyo 107 0062, Japan
    J Refract Surg 21:77-81. 2005
    To establish the risk of ocular rupture after proposed surgical reversal of presbyopia by anterior ciliary sclerotomy (ACS) or by the Er:YAG laser (HOYA Continuum, Tokyo, Japan).
  58. ncbi Aspheric wavefront-guided LASIK to treat hyperopic presbyopia: 12-month results with the VISX platform
    W Bruce Jackson
    University of Ottawa Eye Institute, Ottawa, Ontario, Canada
    J Refract Surg 27:519-29. 2011
    ..To evaluate an aspheric ablation profile to improve near vision in presbyopic patients with hyperopia and to outline the key factors of success...
  59. ncbi Anticipation of presbyopia in Portuguese familial amyloidosis ATTR V30M
    Melo Beirão
    Opthalmology, Centro Hospitalar do Porto, Porto, Portugal
    Amyloid 18:92-7. 2011
    ..if Portuguese patients with familial amyloidosis, liver transplanted and not, have an earlier development of presbyopia compared with a normal population and its relation with the presence or the absence of anterior capsule ..
  60. ncbi Implantation of scleral expansion band segments for the treatment of presbyopia
    Mujtaba A Qazi
    Pepose Vision Institute, Chesterfield, Missouri 63017, USA
    Am J Ophthalmol 134:808-15. 2002
    ....
  61. ncbi Refractive error and presbyopia in timor-leste: the impact of 5 years of a national spectacle program
    Jacqueline Ramke
    The Fred Hollows Foundation New Zealand, Auckland, New Zealand
    Invest Ophthalmol Vis Sci 53:434-9. 2012
    To characterize refractive error, presbyopia, and spectacle correction among adults aged ≥40 years in Timor-Leste in 2010 and examine the impact of the National Spectacle Program by comparing results to those obtained 5 years earlier.
  62. ncbi Designing multifocal corneal models to correct presbyopia by laser ablation
    Aixa Alarcón
    University of Granada, Laboratory of Vision Sciences and ApplicationsLaboratory of Vision Sciences and Applications, Department of Optics, Edificio Mecenas, Facultad de Ciencias, Avda Fuentenueva s n, 18071 Granada, Spain
    J Biomed Opt 17:018001. 2012
    Two multifocal corneal models and an aspheric model designed to correct presbyopia by corneal photoablation were evaluated...
  63. ncbi Removability of a small aperture intracorneal inlay for presbyopia correction
    Jorge L Alio
    Vissum Corporación, Alicante, Spain
    J Refract Surg 29:550-6. 2013
    ..To evaluate the safety of the corneal inlay removal procedure and the reversibility of visual acuities, corneal topography, and corneal biomicroscopy changes in a series of cases...
  64. ncbi Massive increase in the stiffness of the human lens nucleus with age: the basis for presbyopia?
    Karl Robert Heys
    Australian Cataract Research Foundation, University of Wollongong, Wollongong, Australia
    Mol Vis 10:956-63. 2004
    ..To determine the stiffness of different regions of human lenses as a function of age, and to correlate the biophysical measurements in the lens center with nuclear water content...
  65. ncbi Anterior ciliary sclerotomy using collagen T-shaped implants for treatment of presbyopia
    Boris Malyugin
    Fyodorov Eye Microsurgery Complex, Beskudnikovsky Blvd, 59 A, Moscow 127486, Russian Federation
    Ann Ophthalmol (Skokie) 40:130-6. 2008
    ..The study revealed that anterior ciliary sclerotomy with collagen T-shaped implants for the treatment of presbyopia is a safe procedure, but the effect is temporary and diminishes with time.
  66. ncbi Visual outcomes and corneal changes after intrastromal femtosecond laser correction of presbyopia
    Nardine Menassa
    Department of Ophthalmology, International Vision Correction Research Centre, University Hospital of Heidelberg, Heidelberg, Germany
    J Cataract Refract Surg 38:765-73. 2012
    To assess the effect of intrastromal femtosecond laser presbyopia treatment on uncorrected near visual acuity (UNVA) and corneal integrity over an 18-month period.
  67. ncbi Accommodative intraocular lenses: current status
    H Burkhard Dick
    Johannes Gutenberg University, Mainz, Germany
    Curr Opin Ophthalmol 16:8-26. 2005
    ..With accommodative effort, the capsular bag expands and the springs express kinetic energy, which might allow the optics to separate as the anterior lens moves forward...
  68. ncbi The mechanism of presbyopia
    Susan A Strenk
    Department of Surgery, Robert Wood Johnson Medical School University of Medicine and Dentistry of New Jersey, Piscataway, NJ 08855, USA
    Prog Retin Eye Res 24:379-93. 2005
    ..Accommodative loss begins during childhood, with symptomatic presbyopia, or presbyopia that affects one's day to day activities, striking during midlife...
  69. ncbi Corneal multifocality with excimer laser for presbyopia correction
    Jorge L Alio
    VISSUM Instituto Oftalmologico de Alicante, Universidad Miguel Hernandez, Alicante, Spain
    Curr Opin Ophthalmol 20:264-71. 2009
    ..To offer a comprehensive perspective on corneal multifocality created by excimer laser surgery, with the different approaches used for the purpose and its reported outcomes...
  70. ncbi Comparison of multifocal and monovision soft contact lens corrections in patients with low-astigmatic presbyopia
    Kathryn Richdale
    The Ohio State University College of Optometry, Columbus, Ohio 43210, USA
    Optom Vis Sci 83:266-73. 2006
    ..The purpose of this study was to assess visual performance and patient satisfaction with two presbyopic soft contact lens modalities...
  71. ncbi Objective evaluation of through-focus optical performance of presbyopia-correcting intraocular lenses using an optical bench system
    Myoung Joon Kim
    Flaum Eye Institute, University of Rochester, Rochester, New York, USA
    J Cataract Refract Surg 37:1305-12. 2011
    TO evaluate spherical aberration and through-focus optical performances of 5 presbyopia-correcting and 2 monofocal intraocular lenses (IOLs).
  72. ncbi Correction of presbyopia in hyperopia with a center-distance, paracentral-near technique using the Technolas 217z platform
    Roberto Pinelli
    Istituto Laser Microchirurgia Oculare, Brescia, Italy
    J Refract Surg 24:494-500. 2008
    To analyze the results of hyperopic patients treated with a peripheral presbyLASIK algorithm for the correction of presbyopia.
  73. ncbi Monitoring and evaluation of refractive error and presbyopia for Vision 2020
    Garry Brian
    The Fred Hollows Foundation New Zealand
    Clin Experiment Ophthalmol 38:249-54; quiz 327-9. 2010
    To develop output and outcome indicators for the correction of refractive error and presbyopia to a level comparable with those advocated by Vision 2020 for cataract.
  74. ncbi Reading performance after implantation of a modified corneal inlay design for the surgical correction of presbyopia: 1-year follow-up
    Alois K Dexl
    University Eye Clinic, Paracelsus Medical University, Salzburg, Austria
    Am J Ophthalmol 153:994-1001.e2. 2012
    ..To evaluate change in different reading performance parameters after monocular ACI7000PDT corneal inlay implantation for the improvement of near and intermediate vision...
  75. pmc Uncorrected refractive error and presbyopia: accommodating the unmet need
    Rupert R A Bourne
    Br J Ophthalmol 91:848-50. 2007
  76. ncbi Comparison of through-focus image sharpness across five presbyopia-correcting intraocular lenses
    Jay S Pepose
    Pepose Vision Institute, and the Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63017, USA
    Am J Ophthalmol 154:20-28.e1. 2012
    To assess through-focus polychromatic image sharpness of 5 FDA-approved presbyopia-correcting intraocular lenses (IOLs) through a range of object vergences and pupil diameters using an image sharpness algorithm.
  77. ncbi Dynamic aspects of accommodation: age and presbyopia
    John A Mordi
    School of Optometry, Inter American University, Hato Rey, Puerto Rico 00918, USA
    Vision Res 44:591-601. 2004
    ..The results are consistent with the Hess-Gullstrand theory of presbyopia.
  78. ncbi Optical surface optimization for the correction of presbyopia
    Guang ming Dai
    VISX, Inc, Santa Clara, CA 95051, USA
    Appl Opt 45:4184-95. 2006
    b>Presbyopia, the gradual loss of accommodation that accompanies aging, can be corrected by creating asphericity in the optical path of the eye...
  79. ncbi Anterior ciliary sclerotomy for treatment of presbyopia: a prospective controlled study
    David Rex Hamilton
    Jules Stein Eye Institute and the UCLA School of Medicine, Los Angeles, California 90024, USA
    Ophthalmology 109:1970-6; discussion 1976-7. 2002
    ..To examine the safety and efficacy of anterior ciliary sclerotomy to restore accommodation in the presbyopic eye...
  80. ncbi Associations of presbyopia with vision-targeted health-related quality of life
    Peter J McDonnell
    Department of Ophthalmology, University of California, Irvine, USA
    Arch Ophthalmol 121:1577-81. 2003
    To evaluate the associations of presbyopia and its correction, particularly monovision optical correction, with vision-targeted health-related quality of life.
  81. ncbi Pseudo-accommodative cornea: a new concept for correction of presbyopia
    Alain Telandro
    CAP OPHTALMOLOGIE, Cannes, France
    J Refract Surg 20:S714-7. 2004
    Efficacy, predictability, stability, and safety of multifocal ablation with a peripheral near zone for correction of myopia, hyperopia, and presbyopia was assessed.
  82. ncbi [Phakic intraocular lens for presbyopia correction]
    Caroline Amaral Ferraz
    Departamento de Oftalmologia, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    Arq Bras Oftalmol 70:603-8. 2007
    To evaluate clinical and refractive results of anterior chamber multifocal phakic intraocular lens Newlife for presbyopia correction considering uncorrected far and near visual acuity and refraction data and also to evaluate safety of ..
  83. ncbi Performance of presbyopia-correcting intraocular lenses in distance optical bench tests
    W Andrew Maxwell
    California Eye Institute, Fresno, California, USA
    J Cataract Refract Surg 35:166-71. 2009
    To compare the optical performance of 6 presbyopia-correcting intraocular lenses (IOLs) of different designs (accommodating or multifocal and aspheric or spheric).
  84. ncbi Comparison of Acri. Smart multifocal IOL, crystalens AT-45 accommodative IOL, and Technovision presbyLASIK for correcting presbyopia
    Sudi Patel
    Research and Development Department, VISSUM Instituto Oftalmologico de Alicante, Spain
    J Refract Surg 24:294-9. 2008
    ..Smart [multifocal] and AT-45 [accommodative]) for correction of distance and near visual acuity with a LASIK procedure for presbyopia (presbyLASIK) and a control group fitted with a standard distance-correcting monofocal IOL (Acrysof).
  85. ncbi Femtosecond laser in situ keratomileusis versus conductive keratoplasty to obtain monovision in patients with emmetropic presbyopia
    Mohammad Ghassan Ayoubi
    Private laser clinic, Southampton, United Kingdom
    J Cataract Refract Surg 36:997-1002. 2010
    ..To compare visual outcomes, complications, and patient satisfaction after femtosecond laser in situ keratomileusis (LASIK) and conductive keratoplasty (CK)...
  86. ncbi Maximizing satisfaction with presbyopia-correcting intraocular lenses: the missing links
    Jay S Pepose
    Pepose Vision Institute, Chesterfield, MO 63017, USA
    Am J Ophthalmol 146:641-8. 2008
    To critically analyze recent studies of presbyopia-correcting intraocular lenses (IOLs) and to examine opportunities to enhance patient satisfaction further.
  87. ncbi Accommodation and presbyopia: the ciliary neuromuscular view
    Mary Ann Croft
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, F4 328 CSC, 600 Highland Avenue, Madison, WI 53792, USA
    Ophthalmol Clin North Am 19:13-24, v. 2006
    b>Presbyopia (literally, "old eye"), the age-related loss of the ability to accommodate, is the most common ocular affliction in the world...
  88. ncbi Refractive lens exchange for presbyopia
    Shahram Kashani
    The Queen s Hospital, BHR Hospitals NHS Trust, Ophthalmology Department, Romford, Essex RM7 OAG, United Kingdom
    Cont Lens Anterior Eye 31:117-21. 2008
    True presbyopia correction still remains one of the main challenges amongst eye professionals...
  89. ncbi Scleral expansion bands for presbyopia
    F J Malecaze
    Service Ophtalmologie, , Place Dr Baylac, 31059 Toulouse Cedex, France
    Ophthalmology 108:2165-71. 2001
    ..CONCLUSIONS: In this study, the outcome of the SEB intervention was characterized by inconsistent and unpredictable results with a low level of patient satisfaction...
  90. ncbi LASIK for hyperopic astigmatism and presbyopia using micro-monovision with the Carl Zeiss Meditec MEL80 platform
    Dan Z Reinstein
    London Vision Clinic, London, UK
    J Refract Surg 25:37-58. 2009
    To evaluate the monocular and binocular outcomes of LASIK for a micro-monovision protocol for the correction of hyperopic astigmatism and presbyopia.
  91. ncbi Refractive enhancement following presbyopia-correcting intraocular lens implantation
    Marian Sue Macsai
    Department of Ophthalmology, Evanston Northwestern Healthcare, Illinois 060026, USA
    Curr Opin Ophthalmol 19:18-21. 2008
    b>Presbyopia-correcting intraocular lenses are widely available. Residual ametropia is one of the most common issues that can result in patient dissatisfaction...
  92. ncbi Presbyopia correcting intraocular lenses: what do I do?
    Randall J Olson
    Am J Ophthalmol 145:593-4. 2008
  93. ncbi Presbyopia, accommodation, and the mature catenary
    D J Coleman
    Department of Ophthalmology, The New York Presbyterian Hospital-Weill Medical College of Cornell University, New York, New York 10021, USA
    Ophthalmology 108:1544-51. 2001
    ..Variable results with surgical procedures for presbyopia are also predictable with the model. These results can be used to provide a basis for intraocular lens design.
  94. ncbi Myopic astigmatism and presbyopia trial
    Howard Savage
    Ambulatory Care Center, Department of Ophthalmology, George Washington University, Washington, DC 20037, USA
    Am J Ophthalmol 135:628-32. 2003
    No prospective double-masked study has evaluated whether low astigmatism benefits or harms patients with presbyopia, whose intermediate and near vision might theoretically benefit from enhanced depth of focus provided by astigmatism...
  95. ncbi Surgical treatment of presbyopia: scleral, corneal, and lenticular
    Georges Baikoff
    Clinique Monticelli, Marseille, France
    Curr Opin Ophthalmol 15:365-9. 2004
    ..most of the problems concerning myopia, hyperopia, and astigmatism, it is perfectly understandable that the surgical treatment of presbyopia should be next on the agenda. It is a new challenge where every possible aspect is explored.
  96. ncbi Growth of the lens: in vitro observations
    Robert C Augusteyn
    Institute for Eye Research and the Vision Cooperative Research Centre, University of New South Wales, Sydney, Australia
    Clin Exp Optom 91:226-39. 2008
    ..the normal functioning of the human lens and its role in the development of disorders of vision, such as presbyopia and cataract, requires a thorough knowledge of how the lens grows and how its properties change with age...
  97. ncbi Numerical modelling of the accommodating lens
    H J Burd
    Department of Engineering Science, University of Oxford, Parks Road, OX1 3PJ, Oxford, UK
    Vision Res 42:2235-251. 2002
    ..than the 29-year lens, suggesting that the modelling procedure is capable of capturing at least some of the features of presbyopia. The model of the 11-year lens shows some anomalous behaviour, and reasons for this are explored.
  98. ncbi Comparison of diffractive and refractive multifocal intraocular lenses in presbyopia treatment
    Ante Barisić
    Eye Clinic Svjetlost, Zagreb, Croatia
    Coll Antropol 32:27-31. 2008
    ..Multifocal), (N=100 eyes, 50 patients) and refractive (ReZoom), (N=100 eyes, 50 patients) MFIOL to patients with presbyopia and hyperopia...
  99. ncbi [Combined implantation of monofocal and multifocal intraocular lenses for presbyopia correction in cataract patients]
    S Mayer
    Klinik fur Augenheilkunde, Vivantes Klinikum Neukölln, Berlin
    Klin Monbl Augenheilkd 225:812-7. 2008
    ..The purpose of this study was to assess uncorrected far and near vision after implantation of a multifocal intraocular lens (IOL) in the second eye in patients with a unilateral monofocal IOL...
  100. ncbi Conductive keratoplasty for presbyopia: 1-year results
    Jason E Stahl
    Durrie Vision, 5520 College Blvd, Ste 201, Overland Park, KS 66211, USA
    J Refract Surg 22:137-44. 2006
    To assess the safety, efficacy, and stability of conductive keratoplasty (CK) in the treatment of presbyopia.
  101. ncbi Changes in the internal structure of the human crystalline lens with age and accommodation
    M Dubbelman
    Department of Physics and Medical Technology, VU Medical Centre, PO Box 7057, 1007 MB, Amsterdam, The Netherlands
    Vision Res 43:2363-75. 2003
    ..With age, the distance between the sulcus (centre of the nucleus) and the cornea does not change. With accommodation, the nucleus becomes thicker, but the thickness of the cortex remains constant...

Research Grants58

  1. Adjustable Injectable Intraocular Lens
    Shiao Chang; Fiscal Year: 2007
    ..The injectable, accommodating light adjustable intraocular lens system proposed to address presbyopia in the cataract patient is comprised of an injectable, gel-filled capsular lens with an adjustable, anterior ..
  2. Development Of An Eye Drop To Treat Presbyopia
    William H Garner; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Encore Vision has identified an innovative treatment for Presbyopia. The aim of the proposed phase I studies is to develop a topical ocular formulation of our co-drug to achieve therapeutic levels of ..
  3. Mechanisms of lens growth regulation
    Xiaohua Gong; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Presbyopia and age-related cataracts (ARC) are two of the most common age-related ocular disorders, and there is no effective way to delay or prevent them...
  4. MRI Biometry of the Pseudophakic Cadaver Eye
    Susan A Strenk; Fiscal Year: 2010
    ..b>Presbyopia is the loss of accommodation with age and industry efforts to provide surgical correction for presbyopia are ..
  5. In Vivo Evaluation of Presbyopia
    Kathryn Richdale; Fiscal Year: 2013
    ..clinician- scientist and 2) further elucidate the structural and mechanical changes associated with presbyopia. One of the NIH's new Roadmap initiatives is to create interdisciplinary research teams that are more "..
  6. A DATABASE OF IOL POSITION AND BEHAVIOR
    Susan A Strenk; Fiscal Year: 2010
    ..b>Presbyopia is the loss of accommodation with age and industry efforts to provide surgical correction for presbyopia are ..
  7. ACCOMMODATIVE CONTACT LENs FOR PRESBYOPIC CORRECTION
    Hongrui Jiang; Fiscal Year: 2011
    DESCRIPTION (Provided by the applicant) Abstract: Presbyopia is the most common ocular affliction and presents an extraordinary public health issue...
  8. Optical coherence tomography equipped wavefront system for studying accommodation
    Ji chang He; Fiscal Year: 2013
    ..study of accommodation is interesting to public health because age-related loss of the accommodation leads to presbyopia in almost every eye and meanwhile inaccurate accommodation increases the risk to develop myopia in ..
  9. Electro-optic adaptive eyeglass for correction of presbyopia
    Guoqiang Li; Fiscal Year: 2013
    Electro-optic adaptive eyeglass for correction of presbyopia Abstract Presbyopia is an age-related loss of accommodation of the human eye that manifests itself as inability to shift focus from distant to near objects...
  10. Curvature Changing Accommodating IOL
    James T Schwiegerling; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Presbyopia is an age-related disorder in which the crystalline lens becomes less flexible, leading to an inability to focus on near objects...
  11. Optomechanical characteristics of lens accommodation
    Fabrice Manns; Fiscal Year: 2013
    ..and to generate new knowledge that will accelerate the development of implants and surgical approaches to treat presbyopia. The project addresses two critical barriers: a) the need for instruments and techniques that measure the ..
  12. Biomechanical understanding of accommodation mechanism with Brillouin microscopy
    Giuliano Scarcelli; Fiscal Year: 2013
    ..by applicant): Every person beyond the age of 50 experiences severe decline of accommodation, leading to presbyopia, with negative consequences in terms of quality of life and work performance...
  13. Homocysteine's role in the causation of presbyopia
    CHARLES PRINCE; Fiscal Year: 2002
    ..tissues- the most commonly observed pathological changes related to the eye are ectopia lentis preceded by presbyopia and severe myopia...
  14. ELECTROLYTE AND FLUID TRANSPORT IN OCULAR MEMBRANES
    Oscar A Candia; Fiscal Year: 2013
    ..Advancing our knowledge of normal lens function is essential for the future development of potential anti-cataract and presbyopia therapies.
  15. Adjustable Injectable Intraocular Lens
    Shiao Chang; Fiscal Year: 2004
    b>Presbyopia is a progressive, age-related loss of accommodation characterized by the loss of the ability of the natural crystalline lens to change its shape to enable focusing at varying distances...
  16. HOMOCYSTEINE MODIFIES BONE MATRIX AND MINERALIZATION
    CHARLES PRINCE; Fiscal Year: 2007
    ..concentrations between 10 and 100 (m/L), ie, occlusive vascular disease, osteoporosis, dementia, and presbyopia. It is important to recognize that these manifestations of elevated homocysteine (Hcy) are generally ..
  17. Sensory-Motor Control of the Binocular Near Response
    Clifton M Schor; Fiscal Year: 2012
    ..Near Response is a basic study of the progressive reduction of accommodative amplitude that occurs with age (presbyopia) and how it influences the coordination of focusing responses and binocular eye alignment (the near response)...
  18. Bubble Based Acoustic Force Elasticity for Presbyopia
    KYLE HOLLMAN; Fiscal Year: 2006
    ..3) Test and refine this method by mapping the spatial distribution of elasticity in tissue with medical significance, the intraocular lens. ..
  19. ETIOLOGY OF CATARACT
    NANCY RAFFERTY; Fiscal Year: 1993
    ..and its associated proteins are involved in maintaining lens shape, in lens accommodation and development of presbyopia, and in formation of certain kinds of cataract when the cytoskeleton is disrupted...
  20. Crystalline lens optics in accommodation and presbyopia
    BIANCA MARIA MACEO; Fiscal Year: 2013
    ..to characterize the optics of the human crystalline lens and to understand its contribution to accommodation and presbyopia. The project is designed to test the hypothesis that age-related changes in the gradient refractive index of the ..
  21. Translational Conference Series: Innovative Optical Solutions to Common Vision Pr
    Kenneth A Polse; Fiscal Year: 2011
    ..The following topics will be covered: 1) optical solutions to presbyopia, an age-related loss in ones ability to focus (accommodate) on nearby objects, 2) surgical solutions to optical ..
  22. Extra-lenticular aspects of accommodation and presbyopia
    PAUL LEON KAUFMAN; Fiscal Year: 2010
    ..5 No individual appears exempt, making presbyopia (literally, "old eye") the most common ocular affliction in the world...
  23. Multiscale Modeling of Accommodation and Presbyopia
    JANE KORETZ; Fiscal Year: 2009
    ..understanding of the human focusing mechanism (accommodation) and the age-related loss of accommodative range (presbyopia)...
  24. SmartlOL Accommodative Intraocular Lens
    Stephen Zhou; Fiscal Year: 2004
    ..advancement in the pursuit of restored vision and accommodation for the millions of people with cataracts and presbyopia. Over 2...
  25. Novel low cost precision plastics molding for healthcare
    Saul Griffith; Fiscal Year: 2005
    Over 150 million Americans spend - $15 billion/yr for corrective eyewear to compensate for refractive error. Presbyopia, the age related loss of accommodation, affects everyone by about age 50...
  26. A HUMAN ACCOMMODATION MODEL
    JANE KORETZ; Fiscal Year: 1991
    ..Resolving this controversy is a matter of importance, since the age-dependent loss of accommodative amplitude - presbyopia - can only be understood, and perhaps arrested, through an understanding of the aging of the accommodative ..
  27. ELLIPTICAL ACCOMMODATIVE INTRAOCULAR LENS
    FAEZEH SARFARAZI; Fiscal Year: 2000
    ..5 million units per year in the U.S. for cataract patients alone, with the potential for additional units for presbyopia therapy.
  28. SEQUENCING OF AN OCULAR NEUROTROPHIC FACTOR
    THOMAS WALLACE; Fiscal Year: 1990
    ..The eye disorders glaucoma and presbyopia may involve the ciliary ganglion through its regulation of aqueous outflow and visual accommodation...
  29. NEW ADJUSTABLE SPECTACLE LENS FOR PRESBYOPIA
    JOSHUA RABINOVICH; Fiscal Year: 1992
    ..Spectacle correction of presbyopia constitutes a large market, and new products have been developed over the years in an effort to improve on ..
  30. INTERACTIONS OF LENS PROTEINS AND SUBUNITS
    RAUL CHIESA; Fiscal Year: 1992
    ..be performed to reveal those altered mechanisms of protein insolubilization involved in nuclear sclerosis and/or presbyopia. Results on the regional differences in these polypeptides will distinguish molecular changes due to aging from ..
  31. Accommodative changes in aging eyes
    Adrian Glasser; Fiscal Year: 2006
    b>Presbyopia, the age related loss of accommodation, affects everyone by about age 50. The impact of presbyopia on society is considerable from an economic and a quality of life standpoint...
  32. Clinical Accommodation Measurement
    Adrian Glasser; Fiscal Year: 2010
    ....
  33. Snapshot Retinal Imaging Polarimeter
    James Schwiegerling; Fiscal Year: 2007
    ..Furthermore, the device could potentially be a low-cost add-on to existing fundus cameras, allowing a more widespread utility than existing devices. [unreadable] [unreadable]..
  34. INTERVENTIONS FOR VISUAL LOSS IN NURSING HOME RESIDENTS
    Sheila West; Fiscal Year: 2002
    ..This trial will answer timely questions of the impact on the functional status of the most frail elderly of modest, potentially sustainable inputs into improving the appropriate utilization of eye care services. ..
  35. AMD AND RISK FACTORS IN A HISPANIC POPULATION
    Sheila West; Fiscal Year: 2003
    ..Such data will advance our understanding of the magnitude of AMD in this ethnic group, and the way in which risk factors relate to AMD in different populations. ..
  36. CILIARY MUSCLE AGING
    Paul Kaufman; Fiscal Year: 2004
    b>Presbyopia, the age-related loss of the ability to accommodate, is the most common ocular affliction, affecting every human over the age of 45 years. Its pathophysiology is poorly understood...
  37. New Approaches to Subjective Refraction
    Thomas Raasch; Fiscal Year: 2003
    ..This includes evaluating this approach to astigmatic determination in trial lens refraction, and in combination with portable optometers. ..
  38. Workshops on Clinical and Basic Ophthalmology Research
    Paul Kaufman; Fiscal Year: 2004
    ..Based on these visits and discussions, collaborative research projects are expected to emerge. A list of broad topics or sub-fields could be identified as thrust areas. ..
  39. Aqueous humor dynamics studies in vivo and in vitro
    PAUL LEON KAUFMAN; Fiscal Year: 2010
    ....
  40. OPTICAL AND RETINAL LIMITS TO HUMAN VISUAL PERFORMANCE
    Larry N Thibos; Fiscal Year: 2010
    ..Project 6. Develop a new concept of wavefront tomography to characterize the 3-dimensional structure of the eye's optical system from a series of wavefront measurements along multiple lines-of-sight. ..
  41. Disparity Processing in Sensory and Motor Functions
    CLIFTON SCHOR; Fiscal Year: 2005
    ..This noise reduction should expand the spatial range of high-resolution stereo-slant perception. ..
  42. TRIAL OF ANTIBIOTICS TO REDUCE RECURRENT TRICHIASIS
    Sheila West; Fiscal Year: 2005
    ..abstract_text> ..
  43. Short-term Training Students-Health Professional Schools
    KENNETH CIUFFREDA; Fiscal Year: 2006
    ..Trainees will consist of optometry students who have just completed either their first or second professional years, and have done well academically (3.5 gpa or better). All will have an undergraduate degree, generally in the sciences. ..
  44. Cataract: Health Disparity for Older African-Americans
    Sheila West; Fiscal Year: 2006
    ..These data will advance the goal of reducing health disparity in visual disability from cataract among older African Americans. ..
  45. VISUAL DEVELOPMENT OF SENSORY AND MOTOR FUNCTIONS
    CLIFTON SCHOR; Fiscal Year: 2007
    ..The results of these experiments should provide definitive answers to several longstanding questions concerning the coordination of binocular control. ..
  46. Parent Care Transitions, Marital Relationships, and Health Outcomes
    Jamila Bookwala; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  47. A DATABASE OF IOL POSITION AND BEHAVIOR
    Susan Strenk; Fiscal Year: 2004
    ....
  48. Latino Eye Health: A Communication Strategy for Diabetes
    Sheila West; Fiscal Year: 2007
    ..Improvements in eye care seeking behaviors should help in avoiding visual loss from diabetic retinopathy and macula edema, the leading causes of visual loss in the working age Latino population. [unreadable] [unreadable]..
  49. Optical modeling of visual corrections
    Pete Kollbaum; Fiscal Year: 2008
    ..These models will have general applicability to other diseased conditions in which visual performance is degraded due to increased optical aberrations. [unreadable] [unreadable]..
  50. Who drives safely? Visual/cognitive predictors in Elders
    Sheila West; Fiscal Year: 2008
    ..This study will provide critical data on the interactive role of vision, visual attention, and cognition in changing older persons driving behaviors, and the resulting effect on driver errors and risk of crashes. ..
  51. Yearly Mass Treatment C. Trachomatis: When Can We Stop?
    Sheila West; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  52. NUCLEAR CATARACT: ROLE OF UV FILTERS AND THE LENS BARRIER
    Roger Truscott; Fiscal Year: 2008
    ..the lens nucleus must undergo a major change in shape on accommodation, understanding the molecular basis of this enormous hardening may also impact on our understanding of presbyopia. [unreadable] [unreadable] [unreadable] [unreadable]
  53. MRI Biometry of the Pseudophakic Cadaver Eye
    Susan Strenk; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): Presbyopia is the loss of accommodation with age and industry efforts to provide surgical correction for presbyopia are vigorously underway as the potential market for such a product is ..
  54. ANTERIOR OCULAR SEGMENT PHYSIOLOGY AND PHARMACOLOGY
    Paul Kaufman; Fiscal Year: 2009
    ..Such knowledge will contribute to the development of new antiglaucoma drugs and perhaps to understanding the underlying biochemical, physiological, and morphological basis of the human open angle glaucomas. ..
  55. Optical Dynamics of Lens Accommodation
    STEPHEN UHLHORN; Fiscal Year: 2005
    This purpose of this project is to better understand the optics of accommodation and presbyopia. The project will test the hypothesis that changes in the refractive index of the lens during accommodation make a significant contribution to ..