papilledema

Summary

Summary: Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)

Top Publications

  1. ncbi Effect of acetazolamide on ocular hemodynamics in pseudotumor cerebri associated with inflammatory bowel disease
    Max A Villain
    Service d Ophtalmologie, Hopital Gui de Chauliac, Centre Hospitalo Universitaire de Montpellier, Montpellier, France
    Am J Ophthalmol 134:778-80. 2002
  2. ncbi Metamorphopsia as an initial complaint of idiopathic intracranial hypertension
    Judith E A Warner
    Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah Health Sciences Center, 50 N Medical Drive, Salt Lake City, UT 84132, USA
    Arch Ophthalmol 123:1003-6. 2005
  3. ncbi Headaches and papilledema secondary to dural arteriovenous malformation
    J U Adelman
    Adelman Headache Center, 510 North Elam Avenue, Greensboro, NC 27403, USA
    Headache 38:621-3. 1998
  4. ncbi Optical coherence tomography demonstrates subretinal macular edema from papilledema
    V J Hoye
    Department of Ophthalmology, Tufts University School of Medicine, Boston, MA, USA
    Arch Ophthalmol 119:1287-90. 2001
  5. ncbi Anemia and papilledema
    Valerie Biousse
    Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
    Am J Ophthalmol 135:437-46. 2003
  6. doi Follow-up of mild papilledema in idiopathic intracranial hypertension with optical coherence tomography
    Gema Rebolleda
    Department of Ophthalmology, Glaucoma Unit, Hospital Ramon y Cajal, Madrid, Spain
    Invest Ophthalmol Vis Sci 50:5197-200. 2009
  7. ncbi Papilledema and obstructive sleep apnea syndrome
    V A Purvin
    Midwest Eye Institute, 201 Pennsylvania Pkwy, Indianapolis, IN 46280, USA
    Arch Ophthalmol 118:1626-30. 2000
  8. ncbi Optic disc edema
    Gregory P Van Stavern
    Department of Ophthalmology, Neurology, and Neurosurgery, Wayne State University, Detroit, Michigan, USA
    Semin Neurol 27:233-43. 2007
  9. ncbi Gene deletion and pharmacological inhibition of aldose reductase protect against retinal ischemic injury
    Alvin K H Cheung
    Department of Anatomy, The University of Hong Kong, Pokfulam Road, Hong Kong, China
    Exp Eye Res 85:608-16. 2007
  10. doi Diagnosis and grading of papilledema in patients with raised intracranial pressure using optical coherence tomography vs clinical expert assessment using a clinical staging scale
    Colin J Scott
    Department of Ophthalmology and Visual Sciences, Carver School of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Arch Ophthalmol 128:705-11. 2010

Research Grants

  1. Edward P Feener; Fiscal Year: 2016
  2. Commercialization of iSONEP, a Humanized Monoclonal Antibody Against the Bioactiv
    ROGER ALLEN SABBADINI; Fiscal Year: 2010
  3. Michael H Elliott; Fiscal Year: 2015
  4. Investigation of autoimmune anti-retinal antibodies in diabetes
    John R Heckenlively; Fiscal Year: 2013
  5. Martin Friedlander; Fiscal Year: 2016
  6. Zsolt Ablonczy; Fiscal Year: 2014
  7. Martin Friedlander; Fiscal Year: 2016
  8. MARILYN EVE SCHNECK; Fiscal Year: 2015
  9. Identification of novel small molecule inhibitors of Arf6 for the treatment of va
    Kirill Ostanin; Fiscal Year: 2013
  10. OPTIC NEUROPATHY FROM MITOCHONDRIAL DERANGEMENT
    Alfredo Sadun; Fiscal Year: 1999

Detail Information

Publications245 found, 100 shown here

  1. ncbi Effect of acetazolamide on ocular hemodynamics in pseudotumor cerebri associated with inflammatory bowel disease
    Max A Villain
    Service d Ophtalmologie, Hopital Gui de Chauliac, Centre Hospitalo Universitaire de Montpellier, Montpellier, France
    Am J Ophthalmol 134:778-80. 2002
    ..To describe the hemodynamic effect of oral acetazolamide administration on ocular perfusion in a patient with pseudotumor cerebri associated with Crohn disease...
  2. ncbi Metamorphopsia as an initial complaint of idiopathic intracranial hypertension
    Judith E A Warner
    Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah Health Sciences Center, 50 N Medical Drive, Salt Lake City, UT 84132, USA
    Arch Ophthalmol 123:1003-6. 2005
  3. ncbi Headaches and papilledema secondary to dural arteriovenous malformation
    J U Adelman
    Adelman Headache Center, 510 North Elam Avenue, Greensboro, NC 27403, USA
    Headache 38:621-3. 1998
    A 21-year-old developed progressive headaches and pulsatile tinnitus. He was found to have papilledema and a pulsatile bruit...
  4. ncbi Optical coherence tomography demonstrates subretinal macular edema from papilledema
    V J Hoye
    Department of Ophthalmology, Tufts University School of Medicine, Boston, MA, USA
    Arch Ophthalmol 119:1287-90. 2001
    OBJECTIVE: To evaluate macular changes in eyes with papilledema from increased intracranial pressure using optical coherence tomography (OCT)...
  5. ncbi Anemia and papilledema
    Valerie Biousse
    Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
    Am J Ophthalmol 135:437-46. 2003
    ..To elucidate the relationship between anemia and raised intracranial pressure (ICP)...
  6. doi Follow-up of mild papilledema in idiopathic intracranial hypertension with optical coherence tomography
    Gema Rebolleda
    Department of Ophthalmology, Glaucoma Unit, Hospital Ramon y Cajal, Madrid, Spain
    Invest Ophthalmol Vis Sci 50:5197-200. 2009
    To evaluate optical coherence tomography (OCT) measurement of peripapillary retinal nerve fiber layer (RNFL) thickness in patients with mild papilledema associated with idiopathic intracranial hypertension.
  7. ncbi Papilledema and obstructive sleep apnea syndrome
    V A Purvin
    Midwest Eye Institute, 201 Pennsylvania Pkwy, Indianapolis, IN 46280, USA
    Arch Ophthalmol 118:1626-30. 2000
    ..To characterize the pathogenesis and clinical features of optic disc edema associated with obstructive sleep apnea syndrome (SAS)...
  8. ncbi Optic disc edema
    Gregory P Van Stavern
    Department of Ophthalmology, Neurology, and Neurosurgery, Wayne State University, Detroit, Michigan, USA
    Semin Neurol 27:233-43. 2007
    ..b>Papilledema implies disc swelling due to elevated intracranial pressure, and can be distinguished from other causes of disc ..
  9. ncbi Gene deletion and pharmacological inhibition of aldose reductase protect against retinal ischemic injury
    Alvin K H Cheung
    Department of Anatomy, The University of Hong Kong, Pokfulam Road, Hong Kong, China
    Exp Eye Res 85:608-16. 2007
    ..Therefore, AR inhibition should be considered for the treatment of retinal ischemic injury often observed in diabetic patients...
  10. doi Diagnosis and grading of papilledema in patients with raised intracranial pressure using optical coherence tomography vs clinical expert assessment using a clinical staging scale
    Colin J Scott
    Department of Ophthalmology and Visual Sciences, Carver School of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Arch Ophthalmol 128:705-11. 2010
    To compare and contrast 2 methods of quantitating papilledema, namely, optical coherence tomography (OCT) and Modified Frisén Scale (MFS).
  11. ncbi [Bilateral papilledema secondary to chronic lymphocytic leukaemia]
    F Saenz-Frances
    Servicio de Oftalmologia, Hospital Clinico Universitario San Carlos, Madrid, Espana
    Arch Soc Esp Oftalmol 82:303-6. 2007
    ..His visual acuity was 20/200 in the right eye and 20/63 in the left eye and he had a bilateral papilledema. Computed tomography and magnetic resonance imaging of the brain and orbit were performed and showed an ..
  12. ncbi Mechanisms of visual loss in papilledema
    Clemens M Schirmer
    Department of Neurosurgery, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA
    Neurosurg Focus 23:E5. 2007
    The term "papilledema" indicates swelling of the optic discs secondary to increased intracranial pressure. Papilledema can be caused by an intracranial mass lesion or by other factors...
  13. pmc A comparison of idiopathic intracranial hypertension with and without papilledema
    Kathleen B Digre
    Department of Ophthalmology, John A Moran Eye Center, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
    Headache 49:185-93. 2009
    To compare clinical features, visual characteristics, and treatment of idiopathic intracranial hypertension patients with and without papilledema.
  14. pmc Headache in Cerebral Venous Thrombosis: incidence, pattern and location in 200 consecutive patients
    Mohammad Wasay
    Department of Medicine Neurology, The Aga Khan University, Karachi, Pakistan
    J Headache Pain 11:137-9. 2010
    ..93 (68%) patients have abnormal findings on neurological examination including papilledema 29 (15%) patients, altered mental status 38 (19%), and focal neurological deficit 45 (22%) patients...
  15. ncbi Neuronal versus glial cell swelling in the ischaemic retina
    Andreas Bringmann
    Department of Ophthalmology and Eye Clinic, Medical Faculty, University of Leipzig, Leipzig, Germany
    Acta Ophthalmol Scand 83:528-38. 2005
    ..Thus, pharmacological modification of the ion and fluid clearance functions of Müller cells may become a novel way to resolve both cytotoxic and vasogenic oedema in the retina...
  16. ncbi Utility of CSF pressure monitoring to identify idiopathic intracranial hypertension without papilledema in patients with chronic daily headache
    M T Torbey
    Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
    Cephalalgia 24:495-502. 2004
    ..of continuous Pcsf monitoring in establishing the diagnosis of idiopathic intracranial hypertension without papilledema (IIHWOP) in chronic daily headache (CDH) patients...
  17. ncbi Bilateral transverse sinus stenosis predicts IIH without papilledema in patients with migraine
    F Bono
    Institute of Neurology, University Magna Graecia, Catanzaro, Italy
    Neurology 67:419-23. 2006
    The headache profile of patients with idiopathic intracranial hypertension without papilledema (IIHWOP) may be indistinguishable from that of migraine...
  18. doi Is idiopathic intracranial hypertension without papilledema a risk factor for migraine progression?
    Roberto De Simone
    Headache Centre, Department of Neurological Sciences, University of Naples Federico II, Via Pansini, 5, 80131, Naples, Italy
    Neurol Sci 31:411-5. 2010
    The association of chronic migraine (CM) with an idiopathic intracranial hypertension without papilledema (IIHWOP), although much more prevalent than expected in clinical series of CM sufferers, is not included among the risk factors for ..
  19. pmc Optical coherence tomography of the swollen optic nerve head: deformation of the peripapillary retinal pigment epithelium layer in papilledema
    Mark J Kupersmith
    Institute for Neurology and Neurosurgery at Roosevelt Hospital and the New York Eye and Ear Infirmary, USA
    Invest Ophthalmol Vis Sci 52:6558-64. 2011
    ..authors compared HD-OCT optic nerve and peripapillary retinal nerve fiber layer (RNFL) findings in eyes with papilledema caused by raised intracranial pressure to findings in eyes with optic disc swelling caused by optic neuritis ..
  20. doi Effect of optic nerve sheath fenestration on papilledema of the operated and the contralateral nonoperated eyes in idiopathic intracranial hypertension
    Adel H Alsuhaibani
    Department of Ophthalmology, King Abdulaziz University Hospital, King Saud University, Riyadh, Saudi Arabia
    Ophthalmology 118:412-4. 2011
    To evaluate the effect of optic nerve sheath fenestration (ONSF) on papilledema grade in the operated eyes and the contralateral nonoperated fellow eyes in patients with idiopathic intracranial hypertension (IIH).
  21. ncbi [A case of papilledema and Arnold-Chiari type I malformation]
    A Pardo Muñoz
    Sección de Retina, Servicio de Oftalmologia, Hospital Ramon y Cajal, Madrid
    Arch Soc Esp Oftalmol 77:449-53. 2002
    A 12-year old girl was brought to the emergency ward because of headache and diplopia for 4 days. Bilateral papilledema was observed. Ancillary studies showed Arnold-Chiari Type I malformation without hydrocephalia...
  22. pmc Resolution of papilledema associated with OSA treatment
    Shahrokh Javaheri
    Sleepcare Diagnostics, Cincinnati, OH, USA
    J Clin Sleep Med 7:399-400. 2011
    ..The association between OSA and papilledema, however, is not well known...
  23. ncbi Pseudotumor cerebri as an important differential diagnosis of papilledema in children
    Felix Distelmaier
    Department of General Pediatrics, Heinrich Heine University Dusseldorf, Moorenstr 5, D 40225 Dusseldorf, Germany
    Brain Dev 28:190-5. 2006
    ..cerebri (PTC) in childhood is a rare but important differential diagnosis in children presenting with papilledema. It is defined as elevated cerebrospinal fluid (CSF) pressure of more than 20 cm H(2)O, normal CSF composition, ..
  24. ncbi Pediatric optic nerve sheath decompression
    Daniel D Thuente
    Duke University Eye Center, Durham, North Carolina 27710, USA
    Ophthalmology 112:724-7. 2005
    ..To review our experience with optic nerve sheath decompression for pediatric pseudotumor cerebri...
  25. doi Ocular involvement in brucellosis
    Gulten Karatas Sungur
    1st Ophthalmology Department, Ankara Training and Research Hospital, Ankara, Turkey
    Can J Ophthalmol 44:598-601. 2009
    ..To report the ocular findings associated with brucellosis...
  26. ncbi Capillary hemangioma of the cauda equina presenting with radiculopathy and papilledema
    Nicola G Ghazi
    Department of Ophthalmology, University of Virginia Health System, PO Box 800715, Charlottesville, Virginia 22908, USA
    J Neuroophthalmol 26:98-102. 2006
    ..Although spinal cord tumors have been associated with papilledema, this is the first report of a capillary hemangioma of the cauda equina in this context...
  27. ncbi Papilledema as a manifestation of a spinal subdural abscess
    Melissa W Ko
    Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, United States
    J Neurol Sci 260:288-92. 2007
    b>Papilledema is an uncommon presentation of spinal cord processes. Spinal subdural abscess (SSA) is a rare site of post-operative infection...
  28. ncbi Primary spinal melanoma with bilateral papilledema
    Gueorgui K Kounin
    Department of Neurosurgery, University Hospital Alexandrovska, Georgi Sofijski 1 Str, 1431 Sofia, Bulgaria
    Clin Neurol Neurosurg 107:525-7. 2005
    ..The only clinical finding was intracranial hypertension with papilledema. A diagnosis of primary CNS melanoma was made after dermatological and ophthalmological consultations, ruled ..
  29. ncbi Papilledema, presenting as reversible loss of vision, in a child with acute lymphoblastic leukemia
    Yasir Iqbal
    Pediatr Blood Cancer 45:72-3. 2005
  30. ncbi Brucella meningitis and papilledema in a child
    J Levy
    Department of Ophthalmology, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel
    Eur J Ophthalmol 15:818-20. 2005
    To report a rare case of Brucella meningitis with papilledema in a child and to discuss the findings of neurobrucellosis in children.
  31. ncbi [Primary diagnosis of syphilis by the ophthalmologist]
    Agnes Ute Porstmann
    Universitätsaugenklinik Charité, Fakultät der Humboldt Universität Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin
    Klin Monbl Augenheilkd 219:349-52. 2002
    ..According to German sources, recent epidemiological data show a considerable increase of syphilis especially among homosexual men in larger cities...
  32. ncbi Comparison of arteritis and nonarteritic anterior ischemic optic neuropathies with the Heidelberg Retina Tomograph
    Helen Danesh-Meyer
    Department of Ophthalmology, University of Auckland, Auckland, New Zealand
    Ophthalmology 112:1104-12. 2005
    ..The purpose of this study is to evaluate the appearance of the optic nerve head in patients after AAION and NAION with the Heidelberg Retina Tomograph (HRT)...
  33. doi [Diagnosing bilateral papilledema]
    M B Rougier
    Unité rétine, uvéites, Neuro Ophtalmologie, Service d Ophtalmologie, Hopital Pellegrin, CHU de Bordeaux, Place Amelie Raba Leon, 33076 Bordeaux, France
    J Fr Ophtalmol 33:424-9. 2010
    ..visual field, fluorescein angiography, and optical coherence tomography are performed in order to differentiate papilledema secondary to increased intracranial pressure from optic disc swelling secondary to optic neuropathy...
  34. doi High incidence of optic disc swelling at very high altitudes
    Martina M Bosch
    Department of Ophthalmology, University Hospital Zurich, Frauenklinikstrasse 24, 8091 Zurich, Switzerland
    Arch Ophthalmol 126:644-50. 2008
    ....
  35. doi "Idiopathic" intracranial hypertension caused by venous sinus thrombosis associated with contraceptive usage
    Marisa A Perez
    Nova Southeastern University College of Optometry, Fort Lauderdale, FL 33328, USA
    Optometry 81:351-8. 2010
    ..Because disc edema often occurs in CVST, and IIH and is evident in other sight- and life-threatening conditions such as intracranial mass lesions, neuroimaging and other ancillary testing must be conducted for definitive diagnosis...
  36. ncbi Cystoid macular edema and papilledema following cataract extraction: a fluorescein fundoscopic and angiographic study. 1966
    J D M Gass
    Retina 23:646-61. 2003
  37. ncbi Bilateral severe visual loss in brucellosis
    Murat Tunc
    Department of Ophthalmology, Duzce Medical School, Abant Izzet Baysal University, Duzce, Turkey
    Ocul Immunol Inflamm 12:233-6. 2004
    ..To report a case of brucellosis with bilateral permanent loss of vision...
  38. ncbi Exudative complications after photodynamic therapy
    Eric R Holz
    Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA
    Arch Ophthalmol 121:1649-52. 2003
  39. ncbi Bilateral peripapillary subretinal neovessel membrane associated with chronic papilledema: report of two cases
    C Nguyen
    Hopital Ophtalmique Jules Gonin, University of Lausanne, Lausanne, Switzerland
    Klin Monbl Augenheilkd 222:275-8. 2005
    Increased intracranial pressure (ICP) usually results in headaches and papilledema with infrequent loss of visual acuity. Peripapillary subretinal neovessel membranes (PSNVM) rarely complicate chronic papilledema.
  40. ncbi Ventriculoperitoneal shunting for idiopathic intracranial hypertension
    Gunnel Bynke
    Neuro Ophthalmology Unit, Department of Ophthalmology, Lund University Hospital, Sweden
    Neurology 63:1314-6. 2004
    ..Seven patients required one or two (a total of nine) surgical revisions. The revision rate was significantly less than in two similar series of patients treated with lumboperitoneal shunt...
  41. ncbi Pseudotumor cerebri in children with sickle cell disease: a case series
    Michael Henry
    Department of Hematology Oncology, Children s National Medical Center, Washington, DC 20010, USA
    Pediatrics 113:e265-9. 2004
    ..A diagnostic funduscopic examination revealed bilateral papilledema without signs of retinopathy in all 3 patients...
  42. ncbi Magnetic resonance imaging in patients diagnosed with papilledema: a comparison of 6 different high-resolution T1- and T2(*)-weighted 3-dimensional and 2-dimensional sequences
    Johannes Seitz
    Department of Diagnostic Radiology, University Hospital of Regensburg, Franz Josef Strauss Allee 11, D 93042 Regensburg, Germany
    J Neuroimaging 12:164-71. 2002
    To evaluate visualization and signal characteristics of macroscopic changes in patients with ophthalmologically stated papilledema and to find a suitable high-resolution magnetic resonance imaging (MRI) protocol.
  43. ncbi Ultrasonographic evaluation of optic disc swelling: comparison with CSLO in idiopathic intracranial hypertension
    C Tamburrelli
    Institute of Ophthalmology, Catholic University, Rome, Italy
    Invest Ophthalmol Vis Sci 41:2960-6. 2000
    To determine the accuracy and reproducibility of ultrasonographic (US) readings of optic disc elevations in patients with papilledema compared with confocal scanning laser ophthalmoscope (CSLO) measurements.
  44. ncbi Changes in weight, papilledema, headache, visual field, and life status in response to diet and metformin in women with idiopathic intracranial hypertension with and without concurrent polycystic ovary syndrome or hyperinsulinemia
    Charles J Glueck
    Cholesterol Center, Jewish Hospital, Cincinnati, Ohio 45229, USA
    Transl Res 148:215-22. 2006
    ..Changes in weight, papilledema, headache, visual fields, and overall life status were prospectively assessed in response to 6 to 14 months on ..
  45. ncbi Diagnostic criteria for idiopathic intracranial hypertension
    Deborah I Friedman
    Department of Neurology, SUNY Upstate Medial University, Syracuse, NY 14642, USA
    Neurology 59:1492-5. 2002
    ..These factors are not addressed in the Modified Dandy Criteria. This report describes updated diagnostic criteria for IIH that may be used for routine patient management and for research purposes...
  46. pmc Reversed papilledema in an MPS VI patient with galsulfase (Naglazyme) therapy
    Selim T Koseoglu
    Children s Hospital Oakland, 5275 Claremont Avenue, Oakland, CA 94618, USA
    Int Ophthalmol 29:267-9. 2009
    ..VI, with complications including ocular hypertension, progressive corneal clouding, optic nerve swelling (or papilledema) often associated with communicating hydrocephalus (Ashworth et al., Eye 20(5), 553-563, 2006; Goldberg et al...
  47. doi Papilledema in patients with Apert, Crouzon, and Pfeiffer syndrome: prevalence, efficacy of treatment, and risk factors
    Natalja Bannink
    Dutch Craniofacial Center, Erasmus Medical Center Sophia Children s Hospital, Rotterdam, The Netherlands
    J Craniofac Surg 19:121-7. 2008
    ..The aims of this study were to determine the prevalence of papilledema in syndromic craniosynostosis, to evaluate the results of the treatment, and to examine the risk factors...
  48. ncbi Optic disk edema associated with sudden-onset anterior uveitis
    Blythe E Monheit
    Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Am J Ophthalmol 140:733-5. 2005
    ..To describe the clinical characteristics and course of optic disk edema (ODE) associated with isolated sudden-onset anterior uveitis...
  49. ncbi Visual loss in syndromic craniosynostosis with papilledema but without other symptoms of intracranial hypertension
    Marjolijn C Bartels
    Department of Ophthalmology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
    J Craniofac Surg 15:1019-22; discussion 1023-4. 2004
    ..Apart from papilledema, there were no other clinical symptoms of intracranial hypertension...
  50. ncbi [A case of papillitis revealing primary syphilis]
    S B'chir Hamzaoui
    Service de Medecine Interne, Hopital Mongi Slim, 2047 Sidi Daoud, La Marsa, Tunisie
    Med Mal Infect 37:67-8. 2007
    ..Syphilitic ocular manifestations are polymorphous and usually occur during the secondary or tertiary stage of syphilis. We report a case of primary syphilis revealed by papillitis...
  51. doi Bilateral transverse sinus stenosis and idiopathic intracranial hypertension without papilledema in chronic tension-type headache
    F Bono
    Institute of Neurology, University Magna Graecia, Campus Germaneto, Viale Europa, 88100 Catanzaro, Italy
    J Neurol 255:807-12. 2008
    ..that bilateral transverse sinus stenosis (BTSS) predicts idiopathic intracranial hypertension without papilledema (IIHWOP) in migraine...
  52. ncbi Papilledema and abducens nerve palsy following ethylene glycol ingestion
    Christina Delany
    Department of Ophthalmology, Loyola University Medical Center, Maywood, Illinois 60153, USA
    Semin Ophthalmol 19:72-4. 2004
    ..In our opinion, the patient developed a left abducens nerve palsy and bilateral disc edema secondary to a transient rise in intracranial pressure after ingestion of ethylene glycol...
  53. ncbi Bilateral papillitis associated with bilateral anterior uveitis in a child
    Igor Kozak
    University of California San Diego, Shiley Eye Center, 0946, 9415 Campus Point Drive, La Jolla, CA 92037, USA
    J Pediatr Ophthalmol Strabismus 44:374-6. 2007
    ..Anterior uveitis resolved with topical therapy in 3 months and optic disk edema and fluorescein leakage 1 month later. Optic nerve function was intact. Resolution of optic disk edema followed that of anterior uveitis with no sequelae...
  54. doi Use of optical coherence tomography to evaluate papilledema and pseudopapilledema
    Gena Heidary
    Neuro Ophthalmology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
    Semin Ophthalmol 25:198-205. 2010
    ..age with symptoms and signs of posture-dependent headaches, pulsatile tinnitus, visual changes, and papilledema. Optical coherence tomography (OCT) has begun to be utilized as an adjunctive, quantitative tool in the ..
  55. doi Cerebral venous thrombosis: analysis of a multicenter cohort from the United States
    Mohammad Wasay
    Aga Khan University, Karachi, Pakistan
    J Stroke Cerebrovasc Dis 17:49-54. 2008
    ..The data regarding diagnosis, prognosis, management, and outcome of patients with cerebral venous thrombosis are limited from the United States...
  56. pmc Polycythemia vera presenting with bilateral papilledema: a rare case report
    S Parija
    Department of Ophthalmology and State Referral Eye Hospital, SCB Medical College, Cuttack, Orissa, India
    Indian J Ophthalmol 56:327-9. 2008
    ..No abnormality was detected in the vitreous. Optic disc showed features of advanced papilledema with normal macula and retinal periphery in both eyes...
  57. doi Now you see it
    Sagun Pendse
    Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Surv Ophthalmol 53:177-82. 2008
    A patient experienced recurrent postural headache, transient visual obscurations, and papilledema. The patient initially presented with papilledema without cerebral venous sinus thrombosis (pseudotumor cerebri, idiopathic intracranial ..
  58. ncbi Clinical features of late-onset pseudotumor cerebri fulfilling the modified dandy criteria
    Sankar Bandyopadhyay
    Department of Medical Education, Marshfield Clinic, 1000 N Oak Avenue, Marshfield, WI 54449, USA
    J Neuroophthalmol 22:9-11. 2002
    ..To characterize the clinical features of patients with pseudotumor cerebri (PTC) fulfilling the Modified Dandy Criteria who were diagnosed at or after the age of 44 years...
  59. ncbi Resolution of optic nerve edema and improved visual function after optic nerve sheath fenestration in a patient with osteopetrosis
    Richard C Allen
    Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Am J Ophthalmol 141:945-7. 2006
    ..To describe the outcome of a patient with visual loss and optic nerve edema that resulted from osteopetrosis who underwent an optic nerve sheath fenestration (ONSF)...
  60. ncbi [Bilateral papilledema in young women: two case reports of benign intracranial hypertension?]
    F Kling
    Service d Ophtalmologie, CHU Morvan, 29609 Brest Cedex, France
    J Fr Ophtalmol 25:835-9. 2002
    We report two cases of bilateral papilledema in young women. The first patient was 15 years old and had experienced headaches and vomiting for one month, but no visual loss...
  61. ncbi [Pseudotumor cerebri or idiopathic cranial hypertension. Neuro-ophthalmologic considerations]
    Tatiana Rosca
    Oftalmologia 54:11-3. 2002
    ..The symptomatology is polymorphous, hard to frame and much more difficult to cure, the diagnosis being one of exclusion...
  62. ncbi Optic disc edema in non-arteritic anterior ischemic optic neuropathy
    Sohan Singh Hayreh
    Department of Ophthalmology and Visual Sciences, College of Medicine, University of Iowa, Iowa City, IA 52242 1091, USA
    Graefes Arch Clin Exp Ophthalmol 245:1107-21. 2007
    ..Steroid therapy was associated with shorter time to resolution of ODE. Resolution of ODE goes through a characteristic evolutionary process...
  63. ncbi The value of white blood cell count in patients with swollen discs
    M G Wirth
    Department of Ophthalmology, University Hospital Zurich, Switzerland
    Klin Monbl Augenheilkd 221:360-3. 2004
    ..A broad differential diagnosis has to be considered in a patient with swollen discs. Myeloproliferative disorders such as leukemia and lymphoma can in rare cases cause infiltrative optic neuropathy...
  64. ncbi [A case of pseudotumor cerebri with improvement of vision after lumboperitoneal shunt]
    Yoko Kasamatsu
    Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan
    Nihon Ganka Gakkai Zasshi 108:375-83. 2004
    ..However, this disorder can cause permanent, severe visual loss. To our knowledge, no reports have described in detail retinal damage resulting from pseudotumor cerebri...
  65. ncbi Bilateral, nearly simultaneous anterior ischemic optic neuropathy complicated by diabetes and bilateral, small, crowded optic discs
    Junko Shibayama
    Department of Ophthalmology, Osaka Medical College, Takatsuki, Japan
    Jpn J Ophthalmol 49:235-8. 2005
    ..Bilateral simultaneous anterior ischemic optic neuropathy (AION) is uncommon. We report a case of bilateral and nearly simultaneously occurring AION...
  66. ncbi Aggressive glioma of adulthood simulating ischemic optic neuropathy
    Helen V Danesh-Meyer
    Department of Ophthalmology, University of Auckland, Private Bag 92019, Auckland, New Zealand
    Arch Ophthalmol 123:694-700. 2005
  67. ncbi Diffusion MR imaging in a case of acute ischemic optic neuropathy
    L S Al-Shafai
    Department of Radiology, National Guard Hospital, Al Ahsa, Saudi Arabia
    AJNR Am J Neuroradiol 27:255-7. 2006
    ..We report the MR imaging findings in a patient presenting with acute ION in whom diffusion imaging showed decreased water mobility as seen in patients with acute brain ischemia...
  68. ncbi Pseudotumor cerebri induced by minocycline therapy for acne vulgaris
    Kiyofumi Mochizuki
    Department of Ophthalmology, JA Gifu Koseiren, Chuno General Hospital, Gifu, Japan
    Jpn J Ophthalmol 46:668-72. 2002
    ..We report a case of a young girl who developed pseudotumor cerebri while taking minocycline for acne vulgaris...
  69. ncbi Sleep apnea and intracranial hypertension in men
    Andrew G Lee
    Department of Ophthalmology, The University of Iowa Hospitals and Clinics, 200 Hawkins Drive PFP, Iowa City, IA 52242, USA
    Ophthalmology 109:482-5. 2002
    ..To investigate sleep apnea as an associated finding in idiopathic intracranial hypertension (IIH) in men...
  70. ncbi [Influence of intracranial pressure decrease in the pseudotumor cerebri syndrome on visual function]
    Z Kalita
    Neurologické oddĕlení Bat ovy nemocnice, Zlin
    Cesk Slov Oftalmol 60:307-12. 2004
    ..After the operation, although the atrophy of the optic nerve head atrophy occurred, the visual acuity was maintained and visual fields sensitivity improved...
  71. ncbi Pseudotumor cerebri in children with Down syndrome
    Neda Esmaili
    School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin 53705, USA
    Ophthalmology 114:1773-8. 2007
    ..To report 4 pediatric Down syndrome patients with optic nerve elevation and pseudotumor cerebri...
  72. ncbi Monitoring visual function in children with syndromic craniosynostosis: a comparison of 3 methods
    Alki Liasis
    Department of Ophthalmology, Great Hospital for Children NHS Trust, London, England
    Arch Ophthalmol 124:1119-26. 2006
    ..To compare visual acuity, optic disc appearance, and transient pattern reversal visual evoked potentials as markers of possible visual dysfunction in children with syndromic craniosynostosis...
  73. ncbi Acute optic neuropathy in Behçet disease
    N Yalçindag
    Department of Ophthalmology, School of Medicine, Ankara University, Ankara Turkey
    Eur J Ophthalmol 14:578-80. 2004
    ..To report a patient with Behcet disease presenting with acute optic neuropathy...
  74. ncbi Periocular corticosteroids in diabetic papillopathy
    A M Mansour
    Department of Ophthalmology, American University of Beirut, Beirut, Lebanon
    Eye (Lond) 19:45-51. 2005
    ..To ascertain the therapeutic effect of periocular corticosteroids in diabetic papillopathy...
  75. ncbi Pseudotumor cerebri associated with Sjögren's syndrome
    Dinu Stanescu
    Department of Ophthalmology, Pitie Salpetriere Hospital, Paris, France
    Graefes Arch Clin Exp Ophthalmol 241:339-42. 2003
    To report a case of papilledema and pseudotumor cerebri developed in association with Sjögren's syndrome.
  76. ncbi Bilateral visual loss complicating liposuction in a patient with idiopathic intracranial hypertension
    Mário Luiz Ribeiro Monteiro
    Division of Ophthalmology, Hospital das Clinicas of the University of São Paulo Medical School, Sao Paulo, Brazil
    J Neuroophthalmol 26:34-7. 2006
    ..Because liposuction is frequently performed on obese patients, physicians should screen for signs and symptoms of IIH before undertaking this procedure...
  77. pmc Nonarteritic anterior ischemic optic neuropathy: natural history of visual outcome
    Sohan Singh Hayreh
    Department of Ophthalmology and Visual Sciences, College of Medicine University of Iowa, Iowa City, Iowa, USA
    Ophthalmology 115:298-305.e2. 2008
    ..To investigate systematically the natural history of visual outcome in nonarteritic anterior ischemic optic neuropathy (NAION)...
  78. doi Nonarteritic anterior ischemic optic neuropathy: clinical characteristics in diabetic patients versus nondiabetic patients
    Sohan Singh Hayreh
    Department of Ophthalmology and Visual Sciences, College of Medicine, University of Iowa, Iowa City, Iowa, USA
    Ophthalmology 115:1818-25. 2008
    ..To investigate various aspects of nonarteritic anterior ischemic optic neuropathy (NA-AION) in patients with diabetes mellitus and to compare them with those in patients without diabetes mellitus...
  79. ncbi Visual outcomes for optic nerve sheath fenestration in pseudotumour cerebri and related conditions
    Sujatha Chandrasekaran
    Department of Ophthalmology, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia
    Clin Experiment Ophthalmol 34:661-5. 2006
    ..To determine the efficacy and safety of optic nerve sheath fenestration, and to identify factors predicting visual field (VF) and visual acuity (VA) in patients with progressive pseudotumour cerebri syndrome...
  80. ncbi Elevated intracranial pressure associated with idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome
    Matthew D Hammond
    Ophthalmology Service, Walter Reed Army Medical Center, 5900 Georgia Avenue NW, Washington, DC 20307, USA
    J Neuroophthalmol 24:221-4. 2004
    ..IRVAN syndrome may present initially with optic nerve swelling and elevated intracranial pressure with subsequent development of the characteristic retinal vascular abnormalities...
  81. ncbi Optic disc structure and shock-induced anterior ischemic optic neuropathy
    Rod Foroozan
    Neuro Ophthalmology Service, Wills Eye Hospital, Thomas Jefferson University, 900 Walnut Street, Philadelphia, PA 19107, USA
    Ophthalmology 110:327-31. 2003
    ....
  82. ncbi Drusen of the optic disc
    Byron L Lam
    Bascom Palmer Eye Institute, 900 NW 17th Street, Miami, FL 33136, USA
    Curr Neurol Neurosci Rep 8:404-8. 2008
    ..is important to avoid unnecessary work-up and to avoid overlooking potential serious conditions such as true papilledema. Disc drusen patients with more-than-expected visual field defects or progressive visual loss should have work-..
  83. ncbi Hypotony maculopathy and papilledema after trabeculectomy in a patient with pseudotumor cerebri
    Dana Faingold
    University Health Network, Toronto Western Hospital and University of Toronto, Ontario, Canada
    J Glaucoma 12:374-8. 2003
  84. ncbi [Benign childhood intracranial hypertension]
    C Orssaud
    Service d'Ophtalmologie du Professeur J.L. Dufier, , , , Paris-France
    J Fr Ophtalmol 24:54-9. 2001
    ..Clinical presentation included headache and visual disturbance such as visual loss and oculomotor nerve palsy. Papilledema was present in nearly all cases...
  85. doi Idiopathic intracranial hypertension and congenital ocular melanocytosis: a new association
    K Ziahosseini
    Br J Ophthalmol 92:1430-1. 2008
  86. doi Long-term follow-up of idiopathic intracranial hypertension: the Iowa experience
    V A Shah
    University of Iowa Hospitals and Clinics, Department of Ophthalmology, 200 Hawkins Drive, PFP, Iowa City, IA 52242 109, USA
    Neurology 70:634-40. 2008
    To evaluate recurrent or delayed worsening of papilledema and visual function in patients with idiopathic intracranial hypertension (IIH) followed for more than 10 years.
  87. ncbi Bilateral anterior ischemic optic neuropathy after liposuction
    Rod Foroozan
    Neuro Ophthalmology Service RF, Cullen Eye Institute, Baylor College of Medicine, 6565 Fannin NC 205, Houston, TX 77030, USA
    J Neuroophthalmol 24:211-3. 2004
    ..Visual function remained stable over a four-month follow-up, with decreased visual acuity and marked constriction of the visual fields. To our knowledge, this is the second reported case of ischemic optic neuropathy in this setting...
  88. ncbi Idiopathic intracranial hypertension (pseudotumor cerebri): descriptive epidemiology, clinical features, and visual outcome in Parma, Italy, 1990 to 1999
    A Carta
    Institute of Ophthalmology, University of Parma, Hospital of Fidenza, Italy
    Eur J Ophthalmol 14:48-54. 2004
    ..To ascertain the annual incidence rate and the clinical features, other than visual outcome, of idiopathic intracranial hypertension (IIH) in Parma, northern Italy...
  89. ncbi Cranial hypertension as first manifestation of Behçet's disease: a case report
    F J Ascaso
    Department of Ophthalmology, University Clinic Hospital, Zaragoza, Spain
    Doc Ophthalmol 105:291-9. 2002
    ..with BD who developed, as first symptom, a typical intracranial hypertension picture with headaches, bilateral papilledema and raised cerebrospinal fluid (CSF) pressure...
  90. ncbi [Benign intracranial hypertension. History, clinical features and treatment in a series of 41 patients]
    F J Rodríguez de Rivera
    Hospital Universitario La Paz, Universidad Autonoma de Madrid, Madrid, Espana
    Rev Neurol 37:801-5. 2003
    ....
  91. ncbi Transverse venous sinus stent placement as treatment for benign intracranial hypertension in a young male: case report and review of the literature
    Sharad Rajpal
    Departments of Neurosurgery and Radiology, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA
    J Neurosurg 102:342-6. 2005
    ..The authors report the case of a 15-year-old boy who presented with headache, papilledema, decreased visual acuity, and diploplia who underwent successful unilateral transverse sinus stenosis stenting ..
  92. ncbi Spinal cord astrocytoma presenting as "idiopathic" intracranial hypertension
    Alyx Porter
    Department of Neurology, Mayo Clinic, Rochester, 200 1st Street SW, Rochester, MN 55905, USA
    Clin Neurol Neurosurg 108:787-9. 2006
    ..We describe a young, non-obese man who presented with increased intracranial pressure, papilledema and visual obscuration...
  93. doi Pseudotumor cerebri presenting as headache
    Deborah I Friedman
    University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 659, Rochester, NY 14642, USA
    Expert Rev Neurother 8:397-407. 2008
    ..Medical and surgical treatments are employed, although evidence-based treatment guidelines do not exist. This review discusses the diagnosis, differential diagnosis and management strategies for patients with PTC...
  94. ncbi A female adolescent with headache, change in vision, and hearing of 'squeaking' noises
    Andrew C Krakowski
    Rady Children s Hospital of San Diego, USA
    Pediatr Ann 36:145-8. 2007
  95. ncbi Ophthalmologic involvement in the syndrome of headache, neurologic deficits, and cerebrospinal fluid lymphocytosis
    David G Morrison
    Department of Ophthalmology, University of Alabama School of Medicine, Birmingham, Alabama, USA
    Ophthalmology 110:115-8. 2003
    To emphasize that papilledema and other ophthalmic manifestations may occur in the syndrome of headache, neurologic deficits, and cerebrospinal fluid lymphocytosis (HaNDL).
  96. ncbi Diabetic papillopathy and nonarteritic anterior ischemic optic neuropathy
    Sohan Singh Hayreh
    Surv Ophthalmol 47:600-2; author reply 602. 2002
  97. ncbi Paroxysmal intracranial hypertension
    D Kidd
    Neuro Ophthalmology Department, The Royal Free Hospital, London, UK
    Eur J Neurol 12:1002-3. 2005
    ....
  98. ncbi Flow velocity and pulsatility of the ocular circulation in chronic intracranial hypertension
    H W Querfurth
    Division of Neurology, St Elizabeth s Medical Center and Tufts University, Boston 02135, USA
    Acta Neurol Scand 105:431-40. 2002
    ..The aim of this study is to examine the relationship of ocular blood flow velocities and pulsatility to intracranial pressure (ICP)...
  99. ncbi Intracranial pressure returns to normal about a month after stopping tetracycline antibiotics
    Bryan J Winn
    Arch Ophthalmol 125:1137-8. 2007
  100. ncbi Idiopathic intracranial hypertension in prepubertal pediatric patients: characteristics, treatment, and outcome
    G S Cinciripini
    Division of Ophthalmology, Childrens Hospital Los Angeles, USC School of Medicine, California, USA
    Am J Ophthalmol 127:178-82. 1999
    ..To report the features of idiopathic intracranial hypertension in prepubertal children, with emphasis on presentation, treatment, and outcome...
  101. ncbi Protective effects of vitamin E forms (alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate) on retinal edema during ischemia-reperfusion injury in the guinea pig retina
    Orhan Aydemir
    Department of Ophthalmology, School of Medicine, Firat Unv Tip Fak Göz Hast AD, Elazig, Turkey
    Int Ophthalmol 25:283-9. 2004
    ....

Research Grants42

  1. Edward P Feener; Fiscal Year: 2016
    ..These studies could reveal new therapeutic strategies to treat diabetic macular edema, a leading cause of vision loss. ..
  2. Commercialization of iSONEP, a Humanized Monoclonal Antibody Against the Bioactiv
    ROGER ALLEN SABBADINI; Fiscal Year: 2010
    ....
  3. Michael H Elliott; Fiscal Year: 2015
    ..The final aim will focus on the role that dysregulation of the Na/K-ATPase plays and how Cav-1 regulates ATPase activity. ..
  4. Investigation of autoimmune anti-retinal antibodies in diabetes
    John R Heckenlively; Fiscal Year: 2013
    ..Specific immunoreactive bands will be processed for mass spectrometry, and candidate proteins will be identified and the correct ones confirmed. ..
  5. Martin Friedlander; Fiscal Year: 2016
    ....
  6. Zsolt Ablonczy; Fiscal Year: 2014
    ....
  7. Martin Friedlander; Fiscal Year: 2016
    ..abstract_text> ..
  8. MARILYN EVE SCHNECK; Fiscal Year: 2015
    ..This will make possible cost savings and the ability to more quickly bring new candidate treatments or interventions to the clinic. ..
  9. Identification of novel small molecule inhibitors of Arf6 for the treatment of va
    Kirill Ostanin; Fiscal Year: 2013
    ....
  10. OPTIC NEUROPATHY FROM MITOCHONDRIAL DERANGEMENT
    Alfredo Sadun; Fiscal Year: 1999
    ..g. papilledema) does not usually lead to degeneration...
  11. MURINE MODEL OF IMMUNOSUPPRESSION INDUCED CMV RETINITIS
    Patrick Cleveland; Fiscal Year: 1991
    ....
  12. Mona K Garvin; Fiscal Year: 2016
    ..SD-OCT), to rapidly and accurately determine the severity of optic nerve swelling in patients diagnosed with papilledema and to ascertain morphological features that differentiate papilledema from other disorders causing optic nerve ..
  13. BEAU BENJAMIN BRUCE; Fiscal Year: 2014
    ..1) assessing the impact and diagnostic capability of non-dilated ocular fundus photography on the diagnosis of papilledema among headache patients presenting to the emergency department, and (2) determining risk factors among headache ..
  14. EXPERIMENTAL PATHOLOGY OF THE OPTIC NERVE
    Douglas Anderson; Fiscal Year: 1991
    The basic goal of this project has been to understand better the underlying pathogenic mechanisms involved in papilledema, optic atrophy, and glaucoma...
  15. GROWTH FACTOR INDUCED TENASCIN C IN DIABETIC RETINOPATHY
    Alexander Ljubimov; Fiscal Year: 2000
    ..3) To attempt to block the VEGF induce migration and angiogenesis in retinal endothelial cultures using neutralizing antibodies to tenascin-C and its binding integrins. ..
  16. METABOLIC AND HOMEOSTATIC MECHANISMS IN RETINA AND RPE
    Barry Winkler; Fiscal Year: 2003
    ..g., diamox) which have been reported to decrease retinal edema. A long-term goal of the second project is to understand better the nature of the interactions between the retina and RPE and factors regulating retinal detachment. ..
  17. MECHANISMS OF DIABETIC RETINOPATHY
    Anthony Adamis; Fiscal Year: 2001
    ..abstract_text> ..
  18. Phase II Trial of Thalidomide in Primary Amyloidosis
    Angela Dispenzieri; Fiscal Year: 2002
    ..The ultimate goal of the proposed studies is to improve the prognosis of patient with this fatal disease. ..
  19. Outcome Measures in Idiopathic Intracranial Hypertension
    Deborah Friedman; Fiscal Year: 2008
    ..Acquire the training, mentoring and experience necessary to conduct independent, funded clinical research in ophthalmologic and neurological disorders Obtain a Masters Degree in Public Health/Clinical Investigator track ..
  20. OCULAR MELANOMA
    Paul Finger; Fiscal Year: 2003
    ..Standardized clinical and data collection procedures will be employed, and standardized forms will be used in all centers. Central training and certification of all study staff will be required. ..
  21. SUBSTANCE P, NO & MICROGLIA IN CNS INFLAMMATION
    Barnett Nathan; Fiscal Year: 2003
    ..SP and NO modulate their effects in CNS inflammation via these cells. Hypothesis 4: The ultimate site for the effects of SP and NO may be the mitochondrial respiratory chain enzymes of these phagocytic cells. ..
  22. fMRI Studies of Retinal Oxygenation in Diabetic Patients
    Gary Trick; Fiscal Year: 2004
    ..The results of this proposed study may aid in the early diagnosis and staging of diabetic retinopathy as well as in the development and application of rational prevention and treatment strategies. ..
  23. Retinal Oxygenation in Diabetic Retinopathy
    BRUCE BERKOWITZ; Fiscal Year: 2004
    ..The results of these studies could lead to the development of a non-invasive real time method for the early evaluation of diabetic retinopathy and its treatment. ..
  24. Prednisone Ocular Myasthenia Gravis Trial Planning Grant
    Mark Kupersmith; Fiscal Year: 2004
    ....
  25. MR STUDIES OF EXPERIMENTAL RETINOPATHY OF PREMATURITY
    BRUCE BERKOWITZ; Fiscal Year: 2001
    ..This work may have broad impact beyond ROP since abnormal blood vessel growth is a common pathobiologic event for other blinding disorders, such as diabetic retinopathy. ..
  26. ARTHEROSCLEROSIS IN INSULIN-RESISTANT, HYPERLIPIDEMIC P*
    David Clemmons; Fiscal Year: 2005
    ....
  27. IGFBP5 AND INTEGRINS AND CONTROLLING IGF1 ACTIONS
    David Clemmons; Fiscal Year: 2002
    ....
  28. Drug Discovery for Diabetic Retinopathy
    DAVID ANTONETTI; Fiscal Year: 2005
    ..These experiments will provide novel, lead compounds that will be further developed to treat macular edema in diabetic retinopathy. ..
  29. Development of a Novel Method for Inhibiting Atherosclerosis in Diabetes
    David Clemmons; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  30. VISION CHANGES IN DIABETES
    Anthony J Adams; Fiscal Year: 2010
    ..It also aids identification of 'at risk'populations for clinical trials of candidate therapies, which may greatly reduce their cost by decreasing the size of the needed sample and the duration of the trial. ..
  31. KININ/PGE INTERACTION IN CONTROL OF INTRAOCULAR PRESSURE
    JERRY WEBB; Fiscal Year: 2009
    ..abstract_text> ..
  32. Chaperones, ROS systems, & IGF-1:Roles in vascular aging
    David Clemmons; Fiscal Year: 2008
    ..abstract_text> ..
  33. Manganese-enhanced MRI Studies of Retinal Neovascularization
    BRUCE BERKOWITZ; Fiscal Year: 2008
    ..The novel methods in this application will also contribute to the advancement of functional MRI for the study of retinal diseases. [unreadable] [unreadable] [unreadable]..
  34. MECHANISMS BY WHICH IGF-I STIMULATES SMOOTH MUSCLE CELLS
    David Clemmons; Fiscal Year: 2007
    ..The results may suggest novel strategies for interfering with these processes to alter the progression of atherosclerosis. ..
  35. NABTC Member Intitution Grant (UCSF Project Leader)
    Susan Chang; Fiscal Year: 2008
    ..The overall goal of this program is to more effectively treat patients with primary brain tumors, especially malignant glioma, with the purpose of increasing the duration and quality of survival. ..
  36. IMMUNE RESPONSES IN MACULAR DEGENERATION
    Scott Cousins; Fiscal Year: 2009
    ..A new focus will be to test the hypothesis that chronic infection of monocytes with cytomegalovirus is one cause for the development of partially-activated monocytes in some ARMD patients. ..
  37. VISUAL ADAPTATION LIMITS AND AGE-RELATED DISEASE
    Alvin Eisner; Fiscal Year: 2002
    ....
  38. AGING AND VASCULOGENESIS IN MACULAR DEGENERATION
    Scott Cousins; Fiscal Year: 2006
    ..We will use a combination of bone marrow transplantation, adoptive transfer and depletion techniques to evaluate the role of CD34 vascular progenitors in CNV formation, and how their function changes with aging. ..
  39. CLINICAL CHARACTERIZATION&GENETICS OF OPTIC NERVE DRUSEN
    Bradley Katz; Fiscal Year: 2005
    ..These data may suggest novel therapies to prevent the visual field loss associated with OND. In addition, these data may yield information about other diseases of the optic nerve. ..
  40. Female Hormones and Vision
    Alvin Eisner; Fiscal Year: 2006
    ..abstract_text> ..