Genomes and Genes
Summary: Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)
Publications245 found, 100 shown here
- Effect of acetazolamide on ocular hemodynamics in pseudotumor cerebri associated with inflammatory bowel diseaseMax A Villain
Service d Ophtalmologie, Hopital Gui de Chauliac, Centre Hospitalo Universitaire de Montpellier, Montpellier, France
Am J Ophthalmol 134:778-80. 2002..To describe the hemodynamic effect of oral acetazolamide administration on ocular perfusion in a patient with pseudotumor cerebri associated with Crohn disease...
- Metamorphopsia as an initial complaint of idiopathic intracranial hypertensionJudith E A Warner
Department of Ophthalmology and Visual Sciences, Moran Eye Center, University of Utah Health Sciences Center, 50 N Medical Drive, Salt Lake City, UT 84132, USA
Arch Ophthalmol 123:1003-6. 2005
- Headaches and papilledema secondary to dural arteriovenous malformationJ U Adelman
Adelman Headache Center, 510 North Elam Avenue, Greensboro, NC 27403, USA
Headache 38:621-3. 1998A 21-year-old developed progressive headaches and pulsatile tinnitus. He was found to have papilledema and a pulsatile bruit...
- Optical coherence tomography demonstrates subretinal macular edema from papilledemaV J Hoye
Department of Ophthalmology, Tufts University School of Medicine, Boston, MA, USA
Arch Ophthalmol 119:1287-90. 2001OBJECTIVE: To evaluate macular changes in eyes with papilledema from increased intracranial pressure using optical coherence tomography (OCT)...
- Anemia and papilledemaValerie Biousse
Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia, USA
Am J Ophthalmol 135:437-46. 2003..To elucidate the relationship between anemia and raised intracranial pressure (ICP)...
- Follow-up of mild papilledema in idiopathic intracranial hypertension with optical coherence tomographyGema Rebolleda
Department of Ophthalmology, Glaucoma Unit, Hospital Ramon y Cajal, Madrid, Spain
Invest Ophthalmol Vis Sci 50:5197-200. 2009To evaluate optical coherence tomography (OCT) measurement of peripapillary retinal nerve fiber layer (RNFL) thickness in patients with mild papilledema associated with idiopathic intracranial hypertension.
- Papilledema and obstructive sleep apnea syndromeV A Purvin
Midwest Eye Institute, 201 Pennsylvania Pkwy, Indianapolis, IN 46280, USA
Arch Ophthalmol 118:1626-30. 2000..To characterize the pathogenesis and clinical features of optic disc edema associated with obstructive sleep apnea syndrome (SAS)...
- Optic disc edemaGregory P Van Stavern
Department of Ophthalmology, Neurology, and Neurosurgery, Wayne State University, Detroit, Michigan, USA
Semin Neurol 27:233-43. 2007..b>Papilledema implies disc swelling due to elevated intracranial pressure, and can be distinguished from other causes of disc ..
- Gene deletion and pharmacological inhibition of aldose reductase protect against retinal ischemic injuryAlvin K H Cheung
Department of Anatomy, The University of Hong Kong, Pokfulam Road, Hong Kong, China
Exp Eye Res 85:608-16. 2007..Therefore, AR inhibition should be considered for the treatment of retinal ischemic injury often observed in diabetic patients...
- Diagnosis and grading of papilledema in patients with raised intracranial pressure using optical coherence tomography vs clinical expert assessment using a clinical staging scaleColin J Scott
Department of Ophthalmology and Visual Sciences, Carver School of Medicine, University of Iowa, Iowa City, IA 52242, USA
Arch Ophthalmol 128:705-11. 2010To compare and contrast 2 methods of quantitating papilledema, namely, optical coherence tomography (OCT) and Modified Frisén Scale (MFS).
- [Bilateral papilledema secondary to chronic lymphocytic leukaemia]F Saenz-Frances
Servicio de Oftalmologia, Hospital Clinico Universitario San Carlos, Madrid, Espana
Arch Soc Esp Oftalmol 82:303-6. 2007..His visual acuity was 20/200 in the right eye and 20/63 in the left eye and he had a bilateral papilledema. Computed tomography and magnetic resonance imaging of the brain and orbit were performed and showed an ..
- Mechanisms of visual loss in papilledemaClemens M Schirmer
Department of Neurosurgery, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA
Neurosurg Focus 23:E5. 2007The term "papilledema" indicates swelling of the optic discs secondary to increased intracranial pressure. Papilledema can be caused by an intracranial mass lesion or by other factors...
- A comparison of idiopathic intracranial hypertension with and without papilledemaKathleen B Digre
Department of Ophthalmology, John A Moran Eye Center, University of Utah Health Sciences Center, Salt Lake City, UT 84132, USA
Headache 49:185-93. 2009To compare clinical features, visual characteristics, and treatment of idiopathic intracranial hypertension patients with and without papilledema.
- Headache in Cerebral Venous Thrombosis: incidence, pattern and location in 200 consecutive patientsMohammad Wasay
Department of Medicine Neurology, The Aga Khan University, Karachi, Pakistan
J Headache Pain 11:137-9. 2010..93 (68%) patients have abnormal findings on neurological examination including papilledema 29 (15%) patients, altered mental status 38 (19%), and focal neurological deficit 45 (22%) patients...
- Neuronal versus glial cell swelling in the ischaemic retinaAndreas Bringmann
Department of Ophthalmology and Eye Clinic, Medical Faculty, University of Leipzig, Leipzig, Germany
Acta Ophthalmol Scand 83:528-38. 2005..Thus, pharmacological modification of the ion and fluid clearance functions of Müller cells may become a novel way to resolve both cytotoxic and vasogenic oedema in the retina...
- Utility of CSF pressure monitoring to identify idiopathic intracranial hypertension without papilledema in patients with chronic daily headacheM T Torbey
Department of Neurology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Cephalalgia 24:495-502. 2004..of continuous Pcsf monitoring in establishing the diagnosis of idiopathic intracranial hypertension without papilledema (IIHWOP) in chronic daily headache (CDH) patients...
- Bilateral transverse sinus stenosis predicts IIH without papilledema in patients with migraineF Bono
Institute of Neurology, University Magna Graecia, Catanzaro, Italy
Neurology 67:419-23. 2006The headache profile of patients with idiopathic intracranial hypertension without papilledema (IIHWOP) may be indistinguishable from that of migraine...
- Is idiopathic intracranial hypertension without papilledema a risk factor for migraine progression?Roberto De Simone
Headache Centre, Department of Neurological Sciences, University of Naples Federico II, Via Pansini, 5, 80131, Naples, Italy
Neurol Sci 31:411-5. 2010The association of chronic migraine (CM) with an idiopathic intracranial hypertension without papilledema (IIHWOP), although much more prevalent than expected in clinical series of CM sufferers, is not included among the risk factors for ..
- Optical coherence tomography of the swollen optic nerve head: deformation of the peripapillary retinal pigment epithelium layer in papilledemaMark J Kupersmith
Institute for Neurology and Neurosurgery at Roosevelt Hospital and the New York Eye and Ear Infirmary, USA
Invest Ophthalmol Vis Sci 52:6558-64. 2011..authors compared HD-OCT optic nerve and peripapillary retinal nerve fiber layer (RNFL) findings in eyes with papilledema caused by raised intracranial pressure to findings in eyes with optic disc swelling caused by optic neuritis ..
- Effect of optic nerve sheath fenestration on papilledema of the operated and the contralateral nonoperated eyes in idiopathic intracranial hypertensionAdel H Alsuhaibani
Department of Ophthalmology, King Abdulaziz University Hospital, King Saud University, Riyadh, Saudi Arabia
Ophthalmology 118:412-4. 2011To evaluate the effect of optic nerve sheath fenestration (ONSF) on papilledema grade in the operated eyes and the contralateral nonoperated fellow eyes in patients with idiopathic intracranial hypertension (IIH).
- [A case of papilledema and Arnold-Chiari type I malformation]A Pardo Muñoz
Sección de Retina, Servicio de Oftalmologia, Hospital Ramon y Cajal, Madrid
Arch Soc Esp Oftalmol 77:449-53. 2002A 12-year old girl was brought to the emergency ward because of headache and diplopia for 4 days. Bilateral papilledema was observed. Ancillary studies showed Arnold-Chiari Type I malformation without hydrocephalia...
- Resolution of papilledema associated with OSA treatmentShahrokh Javaheri
Sleepcare Diagnostics, Cincinnati, OH, USA
J Clin Sleep Med 7:399-400. 2011..The association between OSA and papilledema, however, is not well known...
- Pseudotumor cerebri as an important differential diagnosis of papilledema in childrenFelix Distelmaier
Department of General Pediatrics, Heinrich Heine University Dusseldorf, Moorenstr 5, D 40225 Dusseldorf, Germany
Brain Dev 28:190-5. 2006..cerebri (PTC) in childhood is a rare but important differential diagnosis in children presenting with papilledema. It is defined as elevated cerebrospinal fluid (CSF) pressure of more than 20 cm H(2)O, normal CSF composition, ..
- Pediatric optic nerve sheath decompressionDaniel D Thuente
Duke University Eye Center, Durham, North Carolina 27710, USA
Ophthalmology 112:724-7. 2005..To review our experience with optic nerve sheath decompression for pediatric pseudotumor cerebri...
- Ocular involvement in brucellosisGulten Karatas Sungur
1st Ophthalmology Department, Ankara Training and Research Hospital, Ankara, Turkey
Can J Ophthalmol 44:598-601. 2009..To report the ocular findings associated with brucellosis...
- Capillary hemangioma of the cauda equina presenting with radiculopathy and papilledemaNicola G Ghazi
Department of Ophthalmology, University of Virginia Health System, PO Box 800715, Charlottesville, Virginia 22908, USA
J Neuroophthalmol 26:98-102. 2006..Although spinal cord tumors have been associated with papilledema, this is the first report of a capillary hemangioma of the cauda equina in this context...
- Papilledema as a manifestation of a spinal subdural abscessMelissa W Ko
Department of Neurology, University of Pennsylvania School of Medicine, Philadelphia, PA, United States
J Neurol Sci 260:288-92. 2007b>Papilledema is an uncommon presentation of spinal cord processes. Spinal subdural abscess (SSA) is a rare site of post-operative infection...
- Primary spinal melanoma with bilateral papilledemaGueorgui K Kounin
Department of Neurosurgery, University Hospital Alexandrovska, Georgi Sofijski 1 Str, 1431 Sofia, Bulgaria
Clin Neurol Neurosurg 107:525-7. 2005..The only clinical finding was intracranial hypertension with papilledema. A diagnosis of primary CNS melanoma was made after dermatological and ophthalmological consultations, ruled ..
- Papilledema, presenting as reversible loss of vision, in a child with acute lymphoblastic leukemiaYasir Iqbal
Pediatr Blood Cancer 45:72-3. 2005
- Brucella meningitis and papilledema in a childJ Levy
Department of Ophthalmology, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel
Eur J Ophthalmol 15:818-20. 2005To report a rare case of Brucella meningitis with papilledema in a child and to discuss the findings of neurobrucellosis in children.
- [Primary diagnosis of syphilis by the ophthalmologist]Agnes Ute Porstmann
Universitätsaugenklinik Charité, Fakultät der Humboldt Universität Berlin, Campus Virchow Klinikum, Augustenburger Platz 1, 13353 Berlin
Klin Monbl Augenheilkd 219:349-52. 2002..According to German sources, recent epidemiological data show a considerable increase of syphilis especially among homosexual men in larger cities...
- Comparison of arteritis and nonarteritic anterior ischemic optic neuropathies with the Heidelberg Retina TomographHelen Danesh-Meyer
Department of Ophthalmology, University of Auckland, Auckland, New Zealand
Ophthalmology 112:1104-12. 2005..The purpose of this study is to evaluate the appearance of the optic nerve head in patients after AAION and NAION with the Heidelberg Retina Tomograph (HRT)...
- [Diagnosing bilateral papilledema]M B Rougier
Unité rétine, uvéites, Neuro Ophtalmologie, Service d Ophtalmologie, Hopital Pellegrin, CHU de Bordeaux, Place Amelie Raba Leon, 33076 Bordeaux, France
J Fr Ophtalmol 33:424-9. 2010..visual field, fluorescein angiography, and optical coherence tomography are performed in order to differentiate papilledema secondary to increased intracranial pressure from optic disc swelling secondary to optic neuropathy...
- High incidence of optic disc swelling at very high altitudesMartina M Bosch
Department of Ophthalmology, University Hospital Zurich, Frauenklinikstrasse 24, 8091 Zurich, Switzerland
Arch Ophthalmol 126:644-50. 2008....
- "Idiopathic" intracranial hypertension caused by venous sinus thrombosis associated with contraceptive usageMarisa A Perez
Nova Southeastern University College of Optometry, Fort Lauderdale, FL 33328, USA
Optometry 81:351-8. 2010..Because disc edema often occurs in CVST, and IIH and is evident in other sight- and life-threatening conditions such as intracranial mass lesions, neuroimaging and other ancillary testing must be conducted for definitive diagnosis...
- Cystoid macular edema and papilledema following cataract extraction: a fluorescein fundoscopic and angiographic study. 1966J D M Gass
Retina 23:646-61. 2003
- Bilateral severe visual loss in brucellosisMurat Tunc
Department of Ophthalmology, Duzce Medical School, Abant Izzet Baysal University, Duzce, Turkey
Ocul Immunol Inflamm 12:233-6. 2004..To report a case of brucellosis with bilateral permanent loss of vision...
- Exudative complications after photodynamic therapyEric R Holz
Cullen Eye Institute, Baylor College of Medicine, Houston, TX 77030, USA
Arch Ophthalmol 121:1649-52. 2003
- Bilateral peripapillary subretinal neovessel membrane associated with chronic papilledema: report of two casesC Nguyen
Hopital Ophtalmique Jules Gonin, University of Lausanne, Lausanne, Switzerland
Klin Monbl Augenheilkd 222:275-8. 2005Increased intracranial pressure (ICP) usually results in headaches and papilledema with infrequent loss of visual acuity. Peripapillary subretinal neovessel membranes (PSNVM) rarely complicate chronic papilledema.
- Ventriculoperitoneal shunting for idiopathic intracranial hypertensionGunnel Bynke
Neuro Ophthalmology Unit, Department of Ophthalmology, Lund University Hospital, Sweden
Neurology 63:1314-6. 2004..Seven patients required one or two (a total of nine) surgical revisions. The revision rate was significantly less than in two similar series of patients treated with lumboperitoneal shunt...
- Pseudotumor cerebri in children with sickle cell disease: a case seriesMichael Henry
Department of Hematology Oncology, Children s National Medical Center, Washington, DC 20010, USA
Pediatrics 113:e265-9. 2004..A diagnostic funduscopic examination revealed bilateral papilledema without signs of retinopathy in all 3 patients...
- Magnetic resonance imaging in patients diagnosed with papilledema: a comparison of 6 different high-resolution T1- and T2(*)-weighted 3-dimensional and 2-dimensional sequencesJohannes Seitz
Department of Diagnostic Radiology, University Hospital of Regensburg, Franz Josef Strauss Allee 11, D 93042 Regensburg, Germany
J Neuroimaging 12:164-71. 2002To evaluate visualization and signal characteristics of macroscopic changes in patients with ophthalmologically stated papilledema and to find a suitable high-resolution magnetic resonance imaging (MRI) protocol.
- Ultrasonographic evaluation of optic disc swelling: comparison with CSLO in idiopathic intracranial hypertensionC Tamburrelli
Institute of Ophthalmology, Catholic University, Rome, Italy
Invest Ophthalmol Vis Sci 41:2960-6. 2000To determine the accuracy and reproducibility of ultrasonographic (US) readings of optic disc elevations in patients with papilledema compared with confocal scanning laser ophthalmoscope (CSLO) measurements.
- Changes in weight, papilledema, headache, visual field, and life status in response to diet and metformin in women with idiopathic intracranial hypertension with and without concurrent polycystic ovary syndrome or hyperinsulinemiaCharles J Glueck
Cholesterol Center, Jewish Hospital, Cincinnati, Ohio 45229, USA
Transl Res 148:215-22. 2006..Changes in weight, papilledema, headache, visual fields, and overall life status were prospectively assessed in response to 6 to 14 months on ..
- Diagnostic criteria for idiopathic intracranial hypertensionDeborah I Friedman
Department of Neurology, SUNY Upstate Medial University, Syracuse, NY 14642, USA
Neurology 59:1492-5. 2002..These factors are not addressed in the Modified Dandy Criteria. This report describes updated diagnostic criteria for IIH that may be used for routine patient management and for research purposes...
- Reversed papilledema in an MPS VI patient with galsulfase (Naglazyme) therapySelim T Koseoglu
Children s Hospital Oakland, 5275 Claremont Avenue, Oakland, CA 94618, USA
Int Ophthalmol 29:267-9. 2009..VI, with complications including ocular hypertension, progressive corneal clouding, optic nerve swelling (or papilledema) often associated with communicating hydrocephalus (Ashworth et al., Eye 20(5), 553-563, 2006; Goldberg et al...
- Papilledema in patients with Apert, Crouzon, and Pfeiffer syndrome: prevalence, efficacy of treatment, and risk factorsNatalja Bannink
Dutch Craniofacial Center, Erasmus Medical Center Sophia Children s Hospital, Rotterdam, The Netherlands
J Craniofac Surg 19:121-7. 2008..The aims of this study were to determine the prevalence of papilledema in syndromic craniosynostosis, to evaluate the results of the treatment, and to examine the risk factors...
- Optic disk edema associated with sudden-onset anterior uveitisBlythe E Monheit
Department of Ophthalmology, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
Am J Ophthalmol 140:733-5. 2005..To describe the clinical characteristics and course of optic disk edema (ODE) associated with isolated sudden-onset anterior uveitis...
- Visual loss in syndromic craniosynostosis with papilledema but without other symptoms of intracranial hypertensionMarjolijn C Bartels
Department of Ophthalmology, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
J Craniofac Surg 15:1019-22; discussion 1023-4. 2004..Apart from papilledema, there were no other clinical symptoms of intracranial hypertension...
- [A case of papillitis revealing primary syphilis]S B'chir Hamzaoui
Service de Medecine Interne, Hopital Mongi Slim, 2047 Sidi Daoud, La Marsa, Tunisie
Med Mal Infect 37:67-8. 2007..Syphilitic ocular manifestations are polymorphous and usually occur during the secondary or tertiary stage of syphilis. We report a case of primary syphilis revealed by papillitis...
- Bilateral transverse sinus stenosis and idiopathic intracranial hypertension without papilledema in chronic tension-type headacheF Bono
Institute of Neurology, University Magna Graecia, Campus Germaneto, Viale Europa, 88100 Catanzaro, Italy
J Neurol 255:807-12. 2008..that bilateral transverse sinus stenosis (BTSS) predicts idiopathic intracranial hypertension without papilledema (IIHWOP) in migraine...
- Papilledema and abducens nerve palsy following ethylene glycol ingestionChristina Delany
Department of Ophthalmology, Loyola University Medical Center, Maywood, Illinois 60153, USA
Semin Ophthalmol 19:72-4. 2004..In our opinion, the patient developed a left abducens nerve palsy and bilateral disc edema secondary to a transient rise in intracranial pressure after ingestion of ethylene glycol...
- Bilateral papillitis associated with bilateral anterior uveitis in a childIgor Kozak
University of California San Diego, Shiley Eye Center, 0946, 9415 Campus Point Drive, La Jolla, CA 92037, USA
J Pediatr Ophthalmol Strabismus 44:374-6. 2007..Anterior uveitis resolved with topical therapy in 3 months and optic disk edema and fluorescein leakage 1 month later. Optic nerve function was intact. Resolution of optic disk edema followed that of anterior uveitis with no sequelae...
- Use of optical coherence tomography to evaluate papilledema and pseudopapilledemaGena Heidary
Neuro Ophthalmology Service, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, MA 02114, USA
Semin Ophthalmol 25:198-205. 2010..age with symptoms and signs of posture-dependent headaches, pulsatile tinnitus, visual changes, and papilledema. Optical coherence tomography (OCT) has begun to be utilized as an adjunctive, quantitative tool in the ..
- Cerebral venous thrombosis: analysis of a multicenter cohort from the United StatesMohammad Wasay
Aga Khan University, Karachi, Pakistan
J Stroke Cerebrovasc Dis 17:49-54. 2008..The data regarding diagnosis, prognosis, management, and outcome of patients with cerebral venous thrombosis are limited from the United States...
- Polycythemia vera presenting with bilateral papilledema: a rare case reportS Parija
Department of Ophthalmology and State Referral Eye Hospital, SCB Medical College, Cuttack, Orissa, India
Indian J Ophthalmol 56:327-9. 2008..No abnormality was detected in the vitreous. Optic disc showed features of advanced papilledema with normal macula and retinal periphery in both eyes...
- Now you see itSagun Pendse
Wills Eye Hospital, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
Surv Ophthalmol 53:177-82. 2008A patient experienced recurrent postural headache, transient visual obscurations, and papilledema. The patient initially presented with papilledema without cerebral venous sinus thrombosis (pseudotumor cerebri, idiopathic intracranial ..
- Clinical features of late-onset pseudotumor cerebri fulfilling the modified dandy criteriaSankar Bandyopadhyay
Department of Medical Education, Marshfield Clinic, 1000 N Oak Avenue, Marshfield, WI 54449, USA
J Neuroophthalmol 22:9-11. 2002..To characterize the clinical features of patients with pseudotumor cerebri (PTC) fulfilling the Modified Dandy Criteria who were diagnosed at or after the age of 44 years...
- Resolution of optic nerve edema and improved visual function after optic nerve sheath fenestration in a patient with osteopetrosisRichard C Allen
Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
Am J Ophthalmol 141:945-7. 2006..To describe the outcome of a patient with visual loss and optic nerve edema that resulted from osteopetrosis who underwent an optic nerve sheath fenestration (ONSF)...
- [Bilateral papilledema in young women: two case reports of benign intracranial hypertension?]F Kling
Service d Ophtalmologie, CHU Morvan, 29609 Brest Cedex, France
J Fr Ophtalmol 25:835-9. 2002We report two cases of bilateral papilledema in young women. The first patient was 15 years old and had experienced headaches and vomiting for one month, but no visual loss...
- [Pseudotumor cerebri or idiopathic cranial hypertension. Neuro-ophthalmologic considerations]Tatiana Rosca
Oftalmologia 54:11-3. 2002..The symptomatology is polymorphous, hard to frame and much more difficult to cure, the diagnosis being one of exclusion...
- Optic disc edema in non-arteritic anterior ischemic optic neuropathySohan Singh Hayreh
Department of Ophthalmology and Visual Sciences, College of Medicine, University of Iowa, Iowa City, IA 52242 1091, USA
Graefes Arch Clin Exp Ophthalmol 245:1107-21. 2007..Steroid therapy was associated with shorter time to resolution of ODE. Resolution of ODE goes through a characteristic evolutionary process...
- The value of white blood cell count in patients with swollen discsM G Wirth
Department of Ophthalmology, University Hospital Zurich, Switzerland
Klin Monbl Augenheilkd 221:360-3. 2004..A broad differential diagnosis has to be considered in a patient with swollen discs. Myeloproliferative disorders such as leukemia and lymphoma can in rare cases cause infiltrative optic neuropathy...
- [A case of pseudotumor cerebri with improvement of vision after lumboperitoneal shunt]Yoko Kasamatsu
Department of Ophthalmology, Teikyo University School of Medicine, Tokyo, Japan
Nihon Ganka Gakkai Zasshi 108:375-83. 2004..However, this disorder can cause permanent, severe visual loss. To our knowledge, no reports have described in detail retinal damage resulting from pseudotumor cerebri...
- Bilateral, nearly simultaneous anterior ischemic optic neuropathy complicated by diabetes and bilateral, small, crowded optic discsJunko Shibayama
Department of Ophthalmology, Osaka Medical College, Takatsuki, Japan
Jpn J Ophthalmol 49:235-8. 2005..Bilateral simultaneous anterior ischemic optic neuropathy (AION) is uncommon. We report a case of bilateral and nearly simultaneously occurring AION...
- Aggressive glioma of adulthood simulating ischemic optic neuropathyHelen V Danesh-Meyer
Department of Ophthalmology, University of Auckland, Private Bag 92019, Auckland, New Zealand
Arch Ophthalmol 123:694-700. 2005
- Diffusion MR imaging in a case of acute ischemic optic neuropathyL S Al-Shafai
Department of Radiology, National Guard Hospital, Al Ahsa, Saudi Arabia
AJNR Am J Neuroradiol 27:255-7. 2006..We report the MR imaging findings in a patient presenting with acute ION in whom diffusion imaging showed decreased water mobility as seen in patients with acute brain ischemia...
- Pseudotumor cerebri induced by minocycline therapy for acne vulgarisKiyofumi Mochizuki
Department of Ophthalmology, JA Gifu Koseiren, Chuno General Hospital, Gifu, Japan
Jpn J Ophthalmol 46:668-72. 2002..We report a case of a young girl who developed pseudotumor cerebri while taking minocycline for acne vulgaris...
- Sleep apnea and intracranial hypertension in menAndrew G Lee
Department of Ophthalmology, The University of Iowa Hospitals and Clinics, 200 Hawkins Drive PFP, Iowa City, IA 52242, USA
Ophthalmology 109:482-5. 2002..To investigate sleep apnea as an associated finding in idiopathic intracranial hypertension (IIH) in men...
- [Influence of intracranial pressure decrease in the pseudotumor cerebri syndrome on visual function]Z Kalita
Neurologické oddĕlení Bat ovy nemocnice, Zlin
Cesk Slov Oftalmol 60:307-12. 2004..After the operation, although the atrophy of the optic nerve head atrophy occurred, the visual acuity was maintained and visual fields sensitivity improved...
- Pseudotumor cerebri in children with Down syndromeNeda Esmaili
School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin 53705, USA
Ophthalmology 114:1773-8. 2007..To report 4 pediatric Down syndrome patients with optic nerve elevation and pseudotumor cerebri...
- Monitoring visual function in children with syndromic craniosynostosis: a comparison of 3 methodsAlki Liasis
Department of Ophthalmology, Great Hospital for Children NHS Trust, London, England
Arch Ophthalmol 124:1119-26. 2006..To compare visual acuity, optic disc appearance, and transient pattern reversal visual evoked potentials as markers of possible visual dysfunction in children with syndromic craniosynostosis...
- Acute optic neuropathy in Behçet diseaseN Yalçindag
Department of Ophthalmology, School of Medicine, Ankara University, Ankara Turkey
Eur J Ophthalmol 14:578-80. 2004..To report a patient with Behcet disease presenting with acute optic neuropathy...
- Periocular corticosteroids in diabetic papillopathyA M Mansour
Department of Ophthalmology, American University of Beirut, Beirut, Lebanon
Eye (Lond) 19:45-51. 2005..To ascertain the therapeutic effect of periocular corticosteroids in diabetic papillopathy...
- Pseudotumor cerebri associated with Sjögren's syndromeDinu Stanescu
Department of Ophthalmology, Pitie Salpetriere Hospital, Paris, France
Graefes Arch Clin Exp Ophthalmol 241:339-42. 2003To report a case of papilledema and pseudotumor cerebri developed in association with Sjögren's syndrome.
- Bilateral visual loss complicating liposuction in a patient with idiopathic intracranial hypertensionMário Luiz Ribeiro Monteiro
Division of Ophthalmology, Hospital das Clinicas of the University of São Paulo Medical School, Sao Paulo, Brazil
J Neuroophthalmol 26:34-7. 2006..Because liposuction is frequently performed on obese patients, physicians should screen for signs and symptoms of IIH before undertaking this procedure...
- Nonarteritic anterior ischemic optic neuropathy: natural history of visual outcomeSohan Singh Hayreh
Department of Ophthalmology and Visual Sciences, College of Medicine University of Iowa, Iowa City, Iowa, USA
Ophthalmology 115:298-305.e2. 2008..To investigate systematically the natural history of visual outcome in nonarteritic anterior ischemic optic neuropathy (NAION)...
- Nonarteritic anterior ischemic optic neuropathy: clinical characteristics in diabetic patients versus nondiabetic patientsSohan Singh Hayreh
Department of Ophthalmology and Visual Sciences, College of Medicine, University of Iowa, Iowa City, Iowa, USA
Ophthalmology 115:1818-25. 2008..To investigate various aspects of nonarteritic anterior ischemic optic neuropathy (NA-AION) in patients with diabetes mellitus and to compare them with those in patients without diabetes mellitus...
- Visual outcomes for optic nerve sheath fenestration in pseudotumour cerebri and related conditionsSujatha Chandrasekaran
Department of Ophthalmology, Royal Prince Alfred Hospital, Camperdown, Sydney, Australia
Clin Experiment Ophthalmol 34:661-5. 2006..To determine the efficacy and safety of optic nerve sheath fenestration, and to identify factors predicting visual field (VF) and visual acuity (VA) in patients with progressive pseudotumour cerebri syndrome...
- Elevated intracranial pressure associated with idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndromeMatthew D Hammond
Ophthalmology Service, Walter Reed Army Medical Center, 5900 Georgia Avenue NW, Washington, DC 20307, USA
J Neuroophthalmol 24:221-4. 2004..IRVAN syndrome may present initially with optic nerve swelling and elevated intracranial pressure with subsequent development of the characteristic retinal vascular abnormalities...
- Optic disc structure and shock-induced anterior ischemic optic neuropathyRod Foroozan
Neuro Ophthalmology Service, Wills Eye Hospital, Thomas Jefferson University, 900 Walnut Street, Philadelphia, PA 19107, USA
Ophthalmology 110:327-31. 2003....
- Drusen of the optic discByron L Lam
Bascom Palmer Eye Institute, 900 NW 17th Street, Miami, FL 33136, USA
Curr Neurol Neurosci Rep 8:404-8. 2008..is important to avoid unnecessary work-up and to avoid overlooking potential serious conditions such as true papilledema. Disc drusen patients with more-than-expected visual field defects or progressive visual loss should have work-..
- Hypotony maculopathy and papilledema after trabeculectomy in a patient with pseudotumor cerebriDana Faingold
University Health Network, Toronto Western Hospital and University of Toronto, Ontario, Canada
J Glaucoma 12:374-8. 2003
- [Benign childhood intracranial hypertension]C Orssaud
Service d'Ophtalmologie du Professeur J.L. Dufier, , , , Paris-France
J Fr Ophtalmol 24:54-9. 2001..Clinical presentation included headache and visual disturbance such as visual loss and oculomotor nerve palsy. Papilledema was present in nearly all cases...
- Idiopathic intracranial hypertension and congenital ocular melanocytosis: a new associationK Ziahosseini
Br J Ophthalmol 92:1430-1. 2008
- Long-term follow-up of idiopathic intracranial hypertension: the Iowa experienceV A Shah
University of Iowa Hospitals and Clinics, Department of Ophthalmology, 200 Hawkins Drive, PFP, Iowa City, IA 52242 109, USA
Neurology 70:634-40. 2008To evaluate recurrent or delayed worsening of papilledema and visual function in patients with idiopathic intracranial hypertension (IIH) followed for more than 10 years.
- Bilateral anterior ischemic optic neuropathy after liposuctionRod Foroozan
Neuro Ophthalmology Service RF, Cullen Eye Institute, Baylor College of Medicine, 6565 Fannin NC 205, Houston, TX 77030, USA
J Neuroophthalmol 24:211-3. 2004..Visual function remained stable over a four-month follow-up, with decreased visual acuity and marked constriction of the visual fields. To our knowledge, this is the second reported case of ischemic optic neuropathy in this setting...
- Idiopathic intracranial hypertension (pseudotumor cerebri): descriptive epidemiology, clinical features, and visual outcome in Parma, Italy, 1990 to 1999A Carta
Institute of Ophthalmology, University of Parma, Hospital of Fidenza, Italy
Eur J Ophthalmol 14:48-54. 2004..To ascertain the annual incidence rate and the clinical features, other than visual outcome, of idiopathic intracranial hypertension (IIH) in Parma, northern Italy...
- Cranial hypertension as first manifestation of Behçet's disease: a case reportF J Ascaso
Department of Ophthalmology, University Clinic Hospital, Zaragoza, Spain
Doc Ophthalmol 105:291-9. 2002..with BD who developed, as first symptom, a typical intracranial hypertension picture with headaches, bilateral papilledema and raised cerebrospinal fluid (CSF) pressure...
- [Benign intracranial hypertension. History, clinical features and treatment in a series of 41 patients]F J Rodríguez de Rivera
Hospital Universitario La Paz, Universidad Autonoma de Madrid, Madrid, Espana
Rev Neurol 37:801-5. 2003....
- Transverse venous sinus stent placement as treatment for benign intracranial hypertension in a young male: case report and review of the literatureSharad Rajpal
Departments of Neurosurgery and Radiology, University of Wisconsin Medical School, Madison, Wisconsin 53792, USA
J Neurosurg 102:342-6. 2005..The authors report the case of a 15-year-old boy who presented with headache, papilledema, decreased visual acuity, and diploplia who underwent successful unilateral transverse sinus stenosis stenting ..
- Spinal cord astrocytoma presenting as "idiopathic" intracranial hypertensionAlyx Porter
Department of Neurology, Mayo Clinic, Rochester, 200 1st Street SW, Rochester, MN 55905, USA
Clin Neurol Neurosurg 108:787-9. 2006..We describe a young, non-obese man who presented with increased intracranial pressure, papilledema and visual obscuration...
- Pseudotumor cerebri presenting as headacheDeborah I Friedman
University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 659, Rochester, NY 14642, USA
Expert Rev Neurother 8:397-407. 2008..Medical and surgical treatments are employed, although evidence-based treatment guidelines do not exist. This review discusses the diagnosis, differential diagnosis and management strategies for patients with PTC...
- A female adolescent with headache, change in vision, and hearing of 'squeaking' noisesAndrew C Krakowski
Rady Children s Hospital of San Diego, USA
Pediatr Ann 36:145-8. 2007
- Ophthalmologic involvement in the syndrome of headache, neurologic deficits, and cerebrospinal fluid lymphocytosisDavid G Morrison
Department of Ophthalmology, University of Alabama School of Medicine, Birmingham, Alabama, USA
Ophthalmology 110:115-8. 2003To emphasize that papilledema and other ophthalmic manifestations may occur in the syndrome of headache, neurologic deficits, and cerebrospinal fluid lymphocytosis (HaNDL).
- Diabetic papillopathy and nonarteritic anterior ischemic optic neuropathySohan Singh Hayreh
Surv Ophthalmol 47:600-2; author reply 602. 2002
- Paroxysmal intracranial hypertensionD Kidd
Neuro Ophthalmology Department, The Royal Free Hospital, London, UK
Eur J Neurol 12:1002-3. 2005....
- Flow velocity and pulsatility of the ocular circulation in chronic intracranial hypertensionH W Querfurth
Division of Neurology, St Elizabeth s Medical Center and Tufts University, Boston 02135, USA
Acta Neurol Scand 105:431-40. 2002..The aim of this study is to examine the relationship of ocular blood flow velocities and pulsatility to intracranial pressure (ICP)...
- Intracranial pressure returns to normal about a month after stopping tetracycline antibioticsBryan J Winn
Arch Ophthalmol 125:1137-8. 2007
- Idiopathic intracranial hypertension in prepubertal pediatric patients: characteristics, treatment, and outcomeG S Cinciripini
Division of Ophthalmology, Childrens Hospital Los Angeles, USC School of Medicine, California, USA
Am J Ophthalmol 127:178-82. 1999..To report the features of idiopathic intracranial hypertension in prepubertal children, with emphasis on presentation, treatment, and outcome...
- Protective effects of vitamin E forms (alpha-tocopherol, gamma-tocopherol and d-alpha-tocopherol polyethylene glycol 1000 succinate) on retinal edema during ischemia-reperfusion injury in the guinea pig retinaOrhan Aydemir
Department of Ophthalmology, School of Medicine, Firat Unv Tip Fak Göz Hast AD, Elazig, Turkey
Int Ophthalmol 25:283-9. 2004....
- Edward P Feener; Fiscal Year: 2016..These studies could reveal new therapeutic strategies to treat diabetic macular edema, a leading cause of vision loss. ..
- Commercialization of iSONEP, a Humanized Monoclonal Antibody Against the BioactivROGER ALLEN SABBADINI; Fiscal Year: 2010....
- Michael H Elliott; Fiscal Year: 2015..The final aim will focus on the role that dysregulation of the Na/K-ATPase plays and how Cav-1 regulates ATPase activity. ..
- Investigation of autoimmune anti-retinal antibodies in diabetesJohn R Heckenlively; Fiscal Year: 2013..Specific immunoreactive bands will be processed for mass spectrometry, and candidate proteins will be identified and the correct ones confirmed. ..
- Martin Friedlander; Fiscal Year: 2016....
- Zsolt Ablonczy; Fiscal Year: 2014....
- Martin Friedlander; Fiscal Year: 2016..abstract_text> ..
- MARILYN EVE SCHNECK; Fiscal Year: 2015..This will make possible cost savings and the ability to more quickly bring new candidate treatments or interventions to the clinic. ..
- Identification of novel small molecule inhibitors of Arf6 for the treatment of vaKirill Ostanin; Fiscal Year: 2013....
- OPTIC NEUROPATHY FROM MITOCHONDRIAL DERANGEMENTAlfredo Sadun; Fiscal Year: 1999..g. papilledema) does not usually lead to degeneration...
- MURINE MODEL OF IMMUNOSUPPRESSION INDUCED CMV RETINITISPatrick Cleveland; Fiscal Year: 1991....
- Mona K Garvin; Fiscal Year: 2016..SD-OCT), to rapidly and accurately determine the severity of optic nerve swelling in patients diagnosed with papilledema and to ascertain morphological features that differentiate papilledema from other disorders causing optic nerve ..
- BEAU BENJAMIN BRUCE; Fiscal Year: 2014..1) assessing the impact and diagnostic capability of non-dilated ocular fundus photography on the diagnosis of papilledema among headache patients presenting to the emergency department, and (2) determining risk factors among headache ..
- EXPERIMENTAL PATHOLOGY OF THE OPTIC NERVEDouglas Anderson; Fiscal Year: 1991The basic goal of this project has been to understand better the underlying pathogenic mechanisms involved in papilledema, optic atrophy, and glaucoma...
- GROWTH FACTOR INDUCED TENASCIN C IN DIABETIC RETINOPATHYAlexander Ljubimov; Fiscal Year: 2000..3) To attempt to block the VEGF induce migration and angiogenesis in retinal endothelial cultures using neutralizing antibodies to tenascin-C and its binding integrins. ..
- METABOLIC AND HOMEOSTATIC MECHANISMS IN RETINA AND RPEBarry Winkler; Fiscal Year: 2003..g., diamox) which have been reported to decrease retinal edema. A long-term goal of the second project is to understand better the nature of the interactions between the retina and RPE and factors regulating retinal detachment. ..
- MECHANISMS OF DIABETIC RETINOPATHYAnthony Adamis; Fiscal Year: 2001..abstract_text> ..
- Phase II Trial of Thalidomide in Primary AmyloidosisAngela Dispenzieri; Fiscal Year: 2002..The ultimate goal of the proposed studies is to improve the prognosis of patient with this fatal disease. ..
- Outcome Measures in Idiopathic Intracranial HypertensionDeborah Friedman; Fiscal Year: 2008..Acquire the training, mentoring and experience necessary to conduct independent, funded clinical research in ophthalmologic and neurological disorders Obtain a Masters Degree in Public Health/Clinical Investigator track ..
- OCULAR MELANOMAPaul Finger; Fiscal Year: 2003..Standardized clinical and data collection procedures will be employed, and standardized forms will be used in all centers. Central training and certification of all study staff will be required. ..
- SUBSTANCE P, NO & MICROGLIA IN CNS INFLAMMATIONBarnett Nathan; Fiscal Year: 2003..SP and NO modulate their effects in CNS inflammation via these cells. Hypothesis 4: The ultimate site for the effects of SP and NO may be the mitochondrial respiratory chain enzymes of these phagocytic cells. ..
- fMRI Studies of Retinal Oxygenation in Diabetic PatientsGary Trick; Fiscal Year: 2004..The results of this proposed study may aid in the early diagnosis and staging of diabetic retinopathy as well as in the development and application of rational prevention and treatment strategies. ..
- Retinal Oxygenation in Diabetic RetinopathyBRUCE BERKOWITZ; Fiscal Year: 2004..The results of these studies could lead to the development of a non-invasive real time method for the early evaluation of diabetic retinopathy and its treatment. ..
- Prednisone Ocular Myasthenia Gravis Trial Planning GrantMark Kupersmith; Fiscal Year: 2004....
- MR STUDIES OF EXPERIMENTAL RETINOPATHY OF PREMATURITYBRUCE BERKOWITZ; Fiscal Year: 2001..This work may have broad impact beyond ROP since abnormal blood vessel growth is a common pathobiologic event for other blinding disorders, such as diabetic retinopathy. ..
- ARTHEROSCLEROSIS IN INSULIN-RESISTANT, HYPERLIPIDEMIC P*David Clemmons; Fiscal Year: 2005....
- IGFBP5 AND INTEGRINS AND CONTROLLING IGF1 ACTIONSDavid Clemmons; Fiscal Year: 2002....
- Drug Discovery for Diabetic RetinopathyDAVID ANTONETTI; Fiscal Year: 2005..These experiments will provide novel, lead compounds that will be further developed to treat macular edema in diabetic retinopathy. ..
- Development of a Novel Method for Inhibiting Atherosclerosis in DiabetesDavid Clemmons; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..
- VISION CHANGES IN DIABETESAnthony J Adams; Fiscal Year: 2010..It also aids identification of 'at risk'populations for clinical trials of candidate therapies, which may greatly reduce their cost by decreasing the size of the needed sample and the duration of the trial. ..
- KININ/PGE INTERACTION IN CONTROL OF INTRAOCULAR PRESSUREJERRY WEBB; Fiscal Year: 2009..abstract_text> ..
- Chaperones, ROS systems, & IGF-1:Roles in vascular agingDavid Clemmons; Fiscal Year: 2008..abstract_text> ..
- Manganese-enhanced MRI Studies of Retinal NeovascularizationBRUCE BERKOWITZ; Fiscal Year: 2008..The novel methods in this application will also contribute to the advancement of functional MRI for the study of retinal diseases. [unreadable] [unreadable] [unreadable]..
- MECHANISMS BY WHICH IGF-I STIMULATES SMOOTH MUSCLE CELLSDavid Clemmons; Fiscal Year: 2007..The results may suggest novel strategies for interfering with these processes to alter the progression of atherosclerosis. ..
- NABTC Member Intitution Grant (UCSF Project Leader)Susan Chang; Fiscal Year: 2008..The overall goal of this program is to more effectively treat patients with primary brain tumors, especially malignant glioma, with the purpose of increasing the duration and quality of survival. ..
- IMMUNE RESPONSES IN MACULAR DEGENERATIONScott Cousins; Fiscal Year: 2009..A new focus will be to test the hypothesis that chronic infection of monocytes with cytomegalovirus is one cause for the development of partially-activated monocytes in some ARMD patients. ..
- VISUAL ADAPTATION LIMITS AND AGE-RELATED DISEASEAlvin Eisner; Fiscal Year: 2002....
- AGING AND VASCULOGENESIS IN MACULAR DEGENERATIONScott Cousins; Fiscal Year: 2006..We will use a combination of bone marrow transplantation, adoptive transfer and depletion techniques to evaluate the role of CD34 vascular progenitors in CNV formation, and how their function changes with aging. ..
- CLINICAL CHARACTERIZATION&GENETICS OF OPTIC NERVE DRUSENBradley Katz; Fiscal Year: 2005..These data may suggest novel therapies to prevent the visual field loss associated with OND. In addition, these data may yield information about other diseases of the optic nerve. ..
- Female Hormones and VisionAlvin Eisner; Fiscal Year: 2006..abstract_text> ..