pathologic nystagmus

Summary

Summary: Involuntary movements of the eye that are divided into two types, jerk and pendular. Jerk nystagmus has a slow phase in one direction followed by a corrective fast phase in the opposite direction, and is usually caused by central or peripheral vestibular dysfunction. Pendular nystagmus features oscillations that are of equal velocity in both directions and this condition is often associated with visual loss early in life. (Adams et al., Principles of Neurology, 6th ed, p272)

Top Publications

  1. ncbi [Benign paroxysmal positional vertigo of the anterior semicircular canal: clinical aspects and treatment]
    P Lorin
    Rev Laryngol Otol Rhinol (Bord) 126:263-6. 2005
  2. ncbi Three-dimensional analysis of benign paroxysmal positional nystagmus in a patient with anterior semicircular canal variant
    Takao Imai
    Department of Otolaryngology, Kansai Rosai Hospital, Hyogo, and Department of Otolaryngology and Sensory Organ Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
    Otol Neurotol 27:362-6. 2006
  3. ncbi Introduction to electronystagmography for END technologists
    Brian A Markley
    The Neurology Center, Silver Spring, Maryland, USA
    Am J Electroneurodiagnostic Technol 47:178-89. 2007
  4. ncbi Vertical nystagmus: clinical facts and hypotheses
    C Pierrot-Deseilligny
    INSERM 679 and Service de Neurologie 1, Hôpital de la Salpêtrière AP HP, Paris, France
    Brain 128:1237-46. 2005
  5. pmc Modified Anderson procedure for correcting abnormal mixed head position in nystagmus
    M E Arroyo-Yllanes
    Pediatric Ophthalmology and Strabismus Clinic, Deparment of Ophthalmology, Hospital General de Mexico, Mexico, DF
    Br J Ophthalmol 86:267-9. 2002
  6. ncbi Surgery for nystagmus related head turn: Kestenbaum procedure and artificial divergence
    M Graf
    Department of Strabology and Neuroophthalmology, University of Giessen, Germany
    Graefes Arch Clin Exp Ophthalmol 239:334-41. 2001
  7. pmc Autoantibodies to glutamic acid decarboxylase in downbeat nystagmus
    G Antonini
    Department of Neurological Sciences, University of Rome, La Sapienza, Rome, Italy
    J Neurol Neurosurg Psychiatry 74:998-9. 2003
  8. pmc Biomechanics of horizontal canal benign paroxysmal positional vertigo
    Suhrud M Rajguru
    Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, USA
    J Vestib Res 15:203-14. 2005
  9. ncbi [Signs and symptoms associated to otoneurologic alterations diagnosed on computerized vestibular exam of patients with multiple sclerosis]
    Andreza Tomaz
    Departamento de Otorrinolaringologia, Irmandade da Santa Casa de Misericordia de Sao Paulo, SP, Brasil
    Arq Neuropsiquiatr 63:837-42. 2005
  10. ncbi [Focus on the BPPV: Semont maneuver for the horizontal canal and anterior canal--differential diagnosis]
    Antonio Carlos Migueis
    Faculte de Medecine, Rua Larga, 3049 Coimbra, Portugal
    Rev Laryngol Otol Rhinol (Bord) 126:193-9. 2005

Detail Information

Publications202 found, 100 shown here

  1. ncbi [Benign paroxysmal positional vertigo of the anterior semicircular canal: clinical aspects and treatment]
    P Lorin
    Rev Laryngol Otol Rhinol (Bord) 126:263-6. 2005
    ..To describe the videonystagmographic characteristics and the treatment of the patients reached with a canalolithiasis or a cupulolithiasis of the anterior semicircular canal...
  2. ncbi Three-dimensional analysis of benign paroxysmal positional nystagmus in a patient with anterior semicircular canal variant
    Takao Imai
    Department of Otolaryngology, Kansai Rosai Hospital, Hyogo, and Department of Otolaryngology and Sensory Organ Surgery, Osaka University Graduate School of Medicine, Osaka, Japan
    Otol Neurotol 27:362-6. 2006
    ..To show the positional nystagmus in a patient who had suffered from benign paroxysmal positional vertigo (BPPV) that was thought to be caused by involvement of the anterior semicircular canal (ASCC) (A-BPPV)...
  3. ncbi Introduction to electronystagmography for END technologists
    Brian A Markley
    The Neurology Center, Silver Spring, Maryland, USA
    Am J Electroneurodiagnostic Technol 47:178-89. 2007
    ..Videonystamography (VNG) is similar to ENG in the data obtained. VNG uses infrared cameras to monitor eye position...
  4. ncbi Vertical nystagmus: clinical facts and hypotheses
    C Pierrot-Deseilligny
    INSERM 679 and Service de Neurologie 1, Hôpital de la Salpêtrière AP HP, Paris, France
    Brain 128:1237-46. 2005
    ....
  5. pmc Modified Anderson procedure for correcting abnormal mixed head position in nystagmus
    M E Arroyo-Yllanes
    Pediatric Ophthalmology and Strabismus Clinic, Deparment of Ophthalmology, Hospital General de Mexico, Mexico, DF
    Br J Ophthalmol 86:267-9. 2002
    ....
  6. ncbi Surgery for nystagmus related head turn: Kestenbaum procedure and artificial divergence
    M Graf
    Department of Strabology and Neuroophthalmology, University of Giessen, Germany
    Graefes Arch Clin Exp Ophthalmol 239:334-41. 2001
    ..We evaluated the effects of Kestenbaum surgery and artificial divergence surgery in a retrospective study...
  7. pmc Autoantibodies to glutamic acid decarboxylase in downbeat nystagmus
    G Antonini
    Department of Neurological Sciences, University of Rome, La Sapienza, Rome, Italy
    J Neurol Neurosurg Psychiatry 74:998-9. 2003
    ..Testing for GAD-Ab may be indicated in DBN patients without an identifiable anatomical brain lesion...
  8. pmc Biomechanics of horizontal canal benign paroxysmal positional vertigo
    Suhrud M Rajguru
    Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, USA
    J Vestib Res 15:203-14. 2005
    ..The model was further applied to assess the efficacy of a 360 degrees -rotation CRP for the treatment of canalithiasis HC-BPPV...
  9. ncbi [Signs and symptoms associated to otoneurologic alterations diagnosed on computerized vestibular exam of patients with multiple sclerosis]
    Andreza Tomaz
    Departamento de Otorrinolaringologia, Irmandade da Santa Casa de Misericordia de Sao Paulo, SP, Brasil
    Arq Neuropsiquiatr 63:837-42. 2005
    ..To identify main symptoms and signs on computerized vestibular testing in patients diagnosed with multiple sclerosis...
  10. ncbi [Focus on the BPPV: Semont maneuver for the horizontal canal and anterior canal--differential diagnosis]
    Antonio Carlos Migueis
    Faculte de Medecine, Rua Larga, 3049 Coimbra, Portugal
    Rev Laryngol Otol Rhinol (Bord) 126:193-9. 2005
  11. ncbi Fabry's disease: otoneurologic findings in twelve members of one family
    Dominique Vibert
    Department of Otorhinolaryngology Head and Neck Surgery, Inselspital, University of Berne, Berne, Switzerland
    Ann Otol Rhinol Laryngol 115:412-8. 2006
    ..Histopathologic evidence of glycosphingolipid accumulation in vascular endothelial and ganglion cells, as well as atrophy of the stria and spiral ligament, might explain the otoneurologic symptoms and findings...
  12. ncbi Immunosuppressive treatment in bilateral vestibulopathy with inner ear antibodies
    Angela Deutschlander
    Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
    Acta Otolaryngol 125:848-51. 2005
    ..These data do not allow us to generally recommend corticosteroid treatment in patients with BVF and inner ear antibodies...
  13. ncbi Contribution of endolymphatic fluid shift to caloric response in plugged semicircular canals
    Tsuyoshi Takenouchi
    Department of Otorhinolaryngology, Tokyo Medical University, Tokyo, Japan
    ORL J Otorhinolaryngol Relat Spec 67:266-71. 2005
    ..The above findings support the hypothesis that fluid shift is responsible for the caloric response without the convective flow of endolymph in the plugged canal...
  14. ncbi A single therapy for all subtypes of horizontal canal positional vertigo
    Wen Yaw Chiou
    Department of Otolaryngology, Songshan Armed Forces Hospital, National Defense Medical Center, No 48, Lane 155, Kuang Fu North Road, Taipei, Taiwan, ROC
    Laryngoscope 115:1432-5. 2005
    ..To demonstrate that a single therapy is effective for treating all subtypes of horizontal canal benign paroxysmal positional vertigo (HC-BPPV)...
  15. ncbi BPPV and variants: improved treatment results with automated, nystagmus-based repositioning
    Meiho Nakayama
    Department of Otorhinolaryngology, Aichi Medical University, Aichigun, Japan
    Otolaryngol Head Neck Surg 133:107-12. 2005
    ..We investigated the efficacy of analyzing and treating positional vertigo with a system that provides unlimited, automated maneuverability of the patient while maintaining constant electronic monitoring of nystagmus...
  16. ncbi Vestibular involvement in myringitis bullosa
    Ron Eliashar
    Department of Otolaryngology Head and Neck Surgery, Hadassah University Hospital, Jerusalem, Israel
    Acta Otolaryngol 124:249-52. 2004
    ..The goal of this study was to investigate the incidence and nature of vestibular involvement in MB...
  17. ncbi Possible central vestibular findings in a patient with a peripheral vestibular disorder
    Kenneth H Brookler
    Neurotologic Associates, PC, New York City, USA
    Ear Nose Throat J 83:520, 522. 2004
  18. ncbi Simultaneous occurrence of a central and a peripheral positional nystagmus during the Dix-Hallpike manoeuvre
    P Bertholon
    Service ORL, CHU de Saint Etienne, Hopital Bellevue, Saint Etienne, France
    Eur Neurol 50:249-50. 2003
  19. ncbi Neurotologic issues
    David M Barrs
    Department of Otolaryngology, Mayo Clinic Scottsdale, Scottsdale, Arizona 85259, USA
    Semin Neurol 23:315-24. 2003
    ..A number of other peripheral vestibular disorders are presented and contrasted with MD...
  20. ncbi Electronystagmographic and caloric investigation data about vascular-vestibular dysfunction among patients with vertebrobasilar insufficiency
    Dorina Petrova
    National Transport Hospital Tzar Boris III, 108 Bd Marie Louise, 1233 Sofia, Bulgaria
    Int Tinnitus J 9:48-51. 2003
    ..Our data from this investigation show that in both rotatory and caloric tests, the slow-phase speed is the most important index about function of the vestibular analyzer...
  21. ncbi Horizontal canal type BPPV: bilaterally affected case treated with canal plugging and Lempert's maneuver
    Arata Horii
    Department of Otolaryngology, Osaka University Medical School, Osaka, Japan
    ORL J Otorhinolaryngol Relat Spec 65:366-9. 2003
    ..Canal plugging combined with Lempert's maneuver to the other side is one treatment option for intractable bilateral horizontal canal BPPV...
  22. ncbi Strong positional nystagmus in an unexpected direction
    Kenneth H Brookler
    Neurotologic Associates, P C, New York City, USA
    Ear Nose Throat J 83:158-9. 2004
  23. ncbi Benign paroxysmal vertigo of childhood
    Jozef Mierzwinski
    Department of Pediatric Otolaryngology, Children s Hospital of Bydgoszcz, Poland
    Otolaryngol Pol 61:307-10. 2007
    ....
  24. ncbi History and ENG findings in a patient with fibrous dysplasia of the skull base
    Kenneth H Brookler
    Neurotologic Associates, P C, New York City, USA
    Ear Nose Throat J 83:314. 2004
  25. ncbi Dynamics of the vestibulo-ocular reflex in patients with the horizontal semicircular canal variant of benign paroxysmal positional vertigo
    Kazunori Sekine
    Department of Otolaryngology, University of Tokushima School of Medicine, Tokushima, Japan
    Acta Otolaryngol 124:587-94. 2004
    ..In this study, we assessed the dynamics of the vestibulo-ocular reflex (VOR) of the HSCC in patients with H-BPPV...
  26. ncbi Subclassification of vestibular disorders by means of statistical analysis in caloric labyrinth testing
    Philip Düwel
    Department of Otorhinolaryngology and Plastic Surgery, University of Aachen, Aachen, Germany
    Acta Otolaryngol 124:595-602. 2004
    ..Therefore, the authors present a multivariate analysis of nystagmus findings with the aim of increasing the precision of diagnostic differentiation in cases of vestibular dysfunction...
  27. ncbi Giant cell arteritis: a new association with benign paroxysmal positional vertigo
    Juan C Amor-Dorado
    Department of Otorhinolaryngology, Hospital Xeral Calde, Lugo, Spain
    Laryngoscope 114:1420-5. 2004
    ..To assess the incidence and characteristics of both benign paroxysmal positional vertigo (BPPV) and positional nystagmus in a series of patients with giant cell arteritis (GCA)...
  28. ncbi Benign paroxysmal positional vertigo due to a simultaneous involvement of both horizontal and posterior semicircular canals
    Takao Imai
    Department of Otolaryngology, Kansai Rosai Hospital, Hyogo, and Department of Otolaryngology, Osaka Universityu Medical School, Japan
    Audiol Neurootol 11:198-205. 2006
    ..The observation of a vertical-torsional positional nystagmus should prompt the specialist to perform not only the canalith repositioning procedure, but also to execute lateral head turns in the supine position...
  29. ncbi Periodic alternating nystagmus in isolated nodular infarction
    H S Jeong
    Department of Neurology, Chungnam University Hospitals 640, Daesa dong, Jung Gu, Daejeon, 301 721, Korea
    Neurology 68:956-7. 2007
  30. ncbi Nystagmus during neck flexion in the pitch plane in benign paroxysmal positional vertigo involving the horizontal canal
    Seung Han Lee
    Department of Neurology, Chonnam National University Medical School, 8 Hak Dong, Dong Gu, Gwangju, South Korea
    J Neurol Sci 256:75-80. 2007
    ..In benign paroxysmal positional vertigo involving the horizontal canal (HC-BPPV), nystagmus may be induced by neck flexion in the pitch plane while sitting (head-bending nystagmus)...
  31. ncbi Predicting a successful treatment in posterior canal benign paroxysmal positional vertigo
    Hui Jong Oh
    MTV Migraine, Tinnitus, and Vertigo Clinic, Oh Neurology Center, 200 13, Icheon dong, Nam Gu, Daegu 705 836, South Korea
    Neurology 68:1219-22. 2007
    ..To elucidate the characteristics and prognostic value of positioning nystagmus during the second position of the Epley maneuver (90 degrees contralateral head turn from the initial Hallpike maneuver)...
  32. ncbi Head-shaking nystagmus in lateral medullary infarction: patterns and possible mechanisms
    K D Choi
    Department of Neurology, College of Medicine, Seoul National University, Seoul National University Bundang Hospital, Seoul, Korea
    Neurology 68:1337-44. 2007
    ..However, the characteristics and diagnostic value of this post-head-shaking nystagmus (HSN) have not been studied systematically in central vestibulopathy, and little is known of the mechanisms involved...
  33. ncbi The high-frequency/acceleration head heave test in detecting otolith diseases
    Paul Kessler
    Department of Otolaryngology, University of Toronto, Toronto, Ontario, Canada
    Otol Neurotol 28:896-904. 2007
    ..To investigate whether transient, high-acceleration interaural head heaves (translational vestibulo-ocular reflex [tVOR]) could aid in the diagnosis of otolith diseases...
  34. ncbi Rotational vertebral artery syndrome: 3D kinematics of nystagmus suggest bilateral labyrinthine dysfunction
    Sarah Marti
    Dept of Neurology, Zurich University Hospital, Frauenklinikstrasse 26, 8091 Zurich, Switzerland
    J Neurol 255:663-7. 2008
    ..With regard to RVAS etiology, our case illustrates a type of pure vascular RVAS. Severity of attacks markedly decreased after successful bilateral carotid endarterectomy...
  35. ncbi Benign paroxysmal positional vertigo of the anterior semicircular canal: atypical clinical findings and possible underlying mechanisms
    S Korres
    ENT Dept, Hippokration Hospital, University of Athens, Greece
    Int J Audiol 47:276-82. 2008
    ..The possible mechanisms responsible for this intriguing variance, as well as guidelines for diagnosing the affected side, are discussed...
  36. ncbi Electronystagmography battery
    Emily Murphy
    Am J Electroneurodiagnostic Technol 48:119-20; author reply 121. 2008
  37. ncbi [Benign paroxysmal positional vertigo in the own material]
    Andrzej Obrebowski
    Katedra i Klinika Foniatrii i Audiologii AM im K Marcinkowskiego w Poznaniu
    Otolaryngol Pol 60:839-43. 2006
    ..It is classically identified by the Dix-Hallpike test. Vestibular and audiology function tests are usually normal. Patient is succesfully treated with physical maneuvres (Canalith Repositioning Procedure CRP)...
  38. ncbi Vertigo in children
    Katarzyna Pawlak-Osińska
    Collegium Medicum of Nicolaus Copernicus University, Bydgoszcz, Poland
    Int Tinnitus J 12:185-9. 2006
    ..We discussed the probable reasons for vertigo, among which psychogenic origin, side effect of medications, hormonal disturbances, spondylosis, and diet errors had to be taken into consideration...
  39. ncbi [Neuro-otological manifestations as presentacion of type I Chiari malformation]
    G Plaza Mayor
    Unidad de Otorrinolaringologia, Fundacion Hospital de Alcorcon
    An Otorrinolaringol Ibero Am 33:613-22. 2006
    ..Due to the coexistence of hydrocephalus and syringomyelia, surgery was indicated. A revision is done on otoneurological presentation of type I Chiari malformation, especially as differential diagnosis on central positional vertigo...
  40. ncbi Prognosis of patients with benign paroxysmal positional vertigo treated with repositioning manoeuvres
    S Korres
    Hippokration Hospital, National University of Athens, Athens, Greece
    J Laryngol Otol 120:528-33. 2006
    ..To evaluate the prognostic factors in benign paroxysmal positional vertigo (BPPV) treated with canalith repositioning procedures (CRPs)...
  41. ncbi Audiovestibular evolution in a patient undergoing surgical resection of a temporal bone myxoma
    Duen Lii Hsieh
    Department of Otolaryngology and Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan
    Eur Arch Otorhinolaryngol 263:614-7. 2006
    ..One year after operation, follow-up audiovestibular function tests revealed normal responses, except for 23 dB conductive hearing loss on the right ear...
  42. ncbi Value of lying-down nystagmus in the lateralization of horizontal semicircular canal benign paroxysmal positional vertigo
    Ja Won Koo
    Department of Otolaryngology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, Korea
    Otol Neurotol 27:367-71. 2006
    ..We studied the values of nystagmus induced by position change from sitting to supine in the lateralization of horizontal canal benign paroxysmal positional vertigo...
  43. ncbi Persistent geotropic nystagmus--a different kind of cupular pathology and its localizing signs
    Johan Bergenius
    Department of Audiology, Karolinska University Hospital, Stockholm, Sweden
    Acta Otolaryngol 126:698-704. 2006
    ..It is possible to determine the side of the affected cupula by recording the nystagmus pattern in yaw and pitch plane...
  44. ncbi Simultaneous acute superior nerve neurolabyrinthitis and benign paroxysmal positional vertigo
    David A Zapala
    Department of Otolaryngology Head and Neck Surgery Audiology, Mayo Clinic, Jacksonville, Florida 32224, USA
    J Am Acad Audiol 17:481-6; quiz 531-2. 2006
    ..However, once the BPPV was identified and treated, the patient's subjective vertigo improved rapidly. Concomitant BPPV should not be overlooked when a diagnosis of acute neurolabyrinthitis is made in the emergency department...
  45. ncbi Localizing forms of nystagmus: symptoms, diagnosis, and treatment
    Andrew G Lee
    Department of Ophthalmology and Visual Sciences, University of Iowa Hospitals and Clinics, The H Stanley Thompson Neuro ophthalmology Clinic, 200 Hawkins Drive, Iowa City, IA 52242, USA
    Curr Neurol Neurosci Rep 6:414-20. 2006
    ..Several optical, medical, and surgical treatments have been used with some success in specific forms of nystagmus...
  46. ncbi 'Bow and lean test' to determine the affected ear of horizontal canal benign paroxysmal positional vertigo
    Yun Hoon Choung
    Department of Otolaryngology, Ajou University School of Medicine, Suwon, South Korea
    Laryngoscope 116:1776-81. 2006
    ..The purpose of this study is to develop the new "bow and lean test (BLT)" to easily determine the affected ear of HSC-BPPV and evaluate its efficiency...
  47. ncbi Audiovestibular disturbance in patients with systemic lupus erythematosus
    Erkan Karatas
    Department of Otolaryngology Head and Neck Surgery, Faculty of Medicine, Gaziantep University, Gaziantep, Turkey
    Otolaryngol Head Neck Surg 136:82-6. 2007
    ..The aim of this study was to evaluate the audiovestibular disturbance in patients with systemic lupus erythematosus (SLE)...
  48. ncbi Superior canal benign positional vertigo
    Jeremy Hornibrook
    N Z Med J 121:67-71. 2008
  49. ncbi Oculo-auricular phenomenon secondary to vestibular dysfunction
    Adriano Jimenez-Escrig
    S de Neurología, Hospital Ramon y Cajal, Madrid, Spain
    Mov Disord 17:1394-5. 2002
    ..We herein describe a 26-year-old man who presented a transient oculo-auricular phenomenon in the course of a vestibular vertigo...
  50. ncbi Benign positioning vertigo (BPV) and three-dimensional (3-D) eye movement analysis
    G Dumas
    Clinique ORL, Centre Hospitalier Albert Michallon, Grenoble, France
    Acta Otorhinolaryngol Belg 52:291-307. 1998
    ....
  51. ncbi [Horizontal canal benign paroxysmal positional vertigo (HC-BPPV) with direction-changing apogeotropic nystagmus: a case with the more-triggering side altering over a short-term]
    Shigetoshi Takaya
    Department of Neurology, Osaka Saiseikai Nakatsu Hospital, 2 10 39 Shibata, Kita ku, Osaka 530 0012, Japan
    No To Shinkei 54:321-5. 2002
    ..Therefore, it may be difficult to apply exercise therapy by determining the affected ear based on the head-position in which more intense nystagmus is evoked...
  52. ncbi Theoretical models for the mechanisms of benign paroxysmal positional vertigo
    Mattew G House
    Victor Goodhill Ear Center, UCLA School of Medicine, Division of Head and Neck Surgery, Los Angeles, Calif 90095 1624, USA
    Audiol Neurootol 8:91-9. 2003
    ..On the basis of these models, several predictions that can help the clinician improve the evaluation of BPPV patients are discussed...
  53. ncbi Vertical semicircular canal function: a study in patients with benign paroxysmal positional vertigo
    M Iida
    Department of Otorhinolaryngology, Tokai University School of Medicine, Kanagawa, Japan
    Acta Otolaryngol Suppl 545:35-7. 2001
    ....
  54. pmc Positional down beating nystagmus in 50 patients: cerebellar disorders and possible anterior semicircular canalithiasis
    P Bertholon
    CHU de Saint Etienne, Hopital Bellevue, Saint Etienne, France
    J Neurol Neurosurg Psychiatry 72:366-72. 2002
    ..To clarify the clinical significance of positional down beat nystagmus (pDBN)...
  55. ncbi Labyrinthectomy versus vestibular neurectomy: long-term physiologic and clinical outcomes
    D J Eisenman
    Department of Otolaryngology-Head and Neck Surgery, Division of Otology-Neurotology, University of Michigan Health System, Ann Arbor, Michigan, USA
    Otol Neurotol 22:539-48. 2001
    ..There is a high incidence of incomplete VC after both procedures, though this does not usually produce a significant balance handicap...
  56. ncbi Observation of vestibular asymmetry in a majority of patients over 50 years with fall-related wrist fractures
    E K Kristinsdottir
    Department of Otorhinolaryngology, Lund University, Sweden
    Acta Otolaryngol 121:481-5. 2001
    ..These findings suggest that an asymmetric vestibular function could be an epidemiologically important contributory factor to falls and wrist fractures among the elderly population...
  57. ncbi Central vertigo and dizziness: epidemiology, differential diagnosis, and common causes
    Mehmet Karatas
    From the Department of Neurology, Baskent University, Medical School, Adana Research Center, Adana, Turkey
    Neurologist 14:355-64. 2008
    ..This article provides an overview of the epidemiology of dizziness, differentiating between central and peripheral vertigo, and central causes of dizziness...
  58. ncbi The effects of gravitoinertial force level and head movements on post-rotational nystagmus and illusory after-rotation
    P DiZio
    Ashton Graybiel Spatial Orientation Laboratory, Brandeis University, Waltham, MA 02254
    Exp Brain Res 70:485-95. 1988
    ..1977; Raphan et al. 1979) and sensations of after-rotation. These same factors are likely to be important etiological elements in space motion sickness...
  59. ncbi Eye movement abnormalities in spinocerebellar ataxia type 17 (SCA17)
    J Hübner
    Department of Neurology, University of Luebeck, Luebeck, Germany
    Neurology 69:1160-8. 2007
    ..In this quantitative characterization of eye movements in SCA17 mutation carriers, we investigated whether eye movement abnormalities originate from multiple lesion sites as suggested by their phenotypic heterogeneity...
  60. ncbi Initial evaluation of vertigo
    Slobodanka Lemajic-Komazec
    Klinika za bolesti uva, grla i nosa, Klinicki centar Novi Sad, Novi Sad
    Med Pregl 59:585-90. 2006
    ..This paper deals with differential diagnosis of vertigo based on anamnesis and clinical examination, as well as objective diagnostic tests...
  61. ncbi [Complex eye movement disturbance in thalamic and mesencephalic infarcts]
    Szilvia Gulyás
    Semmelweis Egyetem, Általános Orvostudományi Kar, Neurológiai Klinika, Budapest
    Ideggyogy Sz 59:193-200. 2006
    ..The authors discuss the mechanism of complex gaze palsy and call attention to the diagnostic value of optokinetic nystagmus examination...
  62. ncbi [Neuro-otological study of Laurence-Moon-Biedl syndrome]
    Y Muratsuka
    Department of Otolaryngology, Hamanomachi Hospital, Fukuoka
    Nippon Jibiinkoka Gakkai Kaiho 94:22-7. 1991
    ..The leftward OKN was limited and bilateral saccadic pursuits observed on eye tracking test. These results suggest that cerebellar of brain-stem lesions may be involved in L-M-B syndrome...
  63. ncbi Electronystagmographic findings in patients with cerebral degenerative disease
    T Tsutsumi
    Department of Otolaryngology, Tokyo Medical and Dental University, Tokyo, Japan
    Acta Otolaryngol Suppl 545:136-9. 2001
    ....
  64. pmc A dose-response analysis of the beneficial effects of the ACTH-(4-9) analogue, Org 2766, on behavioural recovery following unilateral labyrinthectomy in guinea-pig
    D P Gilchrist
    Department of Psychology, University of Otago, Dunedin, New Zealand
    Br J Pharmacol 111:358-63. 1994
    ..Org 2766 did not have the same effect on. postural compensation as it had on the compensation of spontaneous nystagmus...
  65. ncbi On nystagmus, saccades, and fixations
    Benjamin W Tatler
    Sussex Centre for Neuroscience, School of Biological Sciences, University of Sussex, Falmer, Brighton BN1 9QG, UK
    Perception 32:167-84. 2003
    ..The relationship between eye movements and perception, following earlier intuitions by Wells and Breuer, was explored by Dodge, and has been of fundamental importance in the direction of vision research over the last century...
  66. ncbi Gaze-stabilizing deficits and latent nystagmus in monkeys with early-onset visual deprivation: role of the pretectal not
    M J Mustari
    Yerkes Regional Primate Research Center and Department of Neurology, Emory University, Atlanta, Georgia 30322, USA
    J Neurophysiol 86:662-75. 2001
    ..We hypothesize that the large proportion of units dominated by the contralateral eye contribute to the development of monocular OKN asymmetries and LN...
  67. ncbi Emergence of diplopia and oscillopsia due to Heimann-Bielschowsky phenomenon after cataract surgery
    S H Jeong
    Department of Neurology, College of Medicine, Seoul National University, Seoul National University Bundang Hospital, Gyeonggi Do, Korea
    Br J Ophthalmol 92:1402. 2008
    ..We report a man who developed persistent vertical diplopia and oscillopsia due to HBP after a cataract operation, which markedly impaired his vision...
  68. ncbi Evaluation of the post-rotational nystagmus test (PRN) in determining alcohol intoxication
    Majda Z Karlovsek
    Institute for Forensic Medicine, Medical Faculty, University of Ljubljana, Slovenia
    J Anal Toxicol 29:390-3. 2005
    ..813. Based on the AUC, the post-rotational nystagmus test is a good test for predicting alcohol intoxication over 0.5 g/kg. As a part of the physician's examination, it contributes significantly to the description of the clinical state...
  69. ncbi Progressive cerebellar ataxia with variable episodic symptoms--phenotypic diversity of R1668W CACNA1A mutation
    Sarah Marti
    Department of Neurology, Zurich University Hospital, Zurich, Switzerland
    Eur Neurol 60:16-20. 2008
    ..Our report highlights profound phenotypic variability that can be associated with CACNA1A mutations and adds important therapeutic considerations...
  70. ncbi Surgical treatment of upgaze palsy in Parinaud's syndrome
    Edward G Buckley
    Pediatric Department, Duke University Eye Center, Durham, NC 27710, USA
    J AAPOS 8:249-53. 2004
    ..There are only a few reports on the treatment of this problem in the literature. Patients with Parinaud's syndrome may also have retraction nystagmus and convergence on attempted upgaze that further complicates the treatment...
  71. ncbi An unusual variant of the dorsal midbrain syndrome in MS: clinical characteristics and pathophysiologic mechanisms
    Elliot M Frohman
    Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
    Mult Scler 10:322-5. 2004
    ..We consider the pathophysiologic mechanisms responsible for our observations and review important details of the dorsal midbrain ocular motor circuitry...
  72. ncbi Convergence retraction nystagmus: a disorder of vergence?
    H Rambold
    Department of Neurology, Medical University of Lubeck, Germany
    Ann Neurol 50:677-81. 2001
    ..The slow phases of CRN showed an exponential decay with a time constant of 70 milliseconds. Thus, CRN is probably a disorder of vergence rather than of opposing adducting saccades...
  73. ncbi Abnormal vergence with upper brainstem infarcts: pseudoabducens palsy
    P Pullicino
    Department of Neurology, State University of New York at Buffalo 14203, USA
    Neurology 55:352-8. 2000
    ..Although the substrate for vergence has been defined in the monkey as lying dorsal and lateral to the oculomotor nucleus, the human homologue is unknown...
  74. ncbi [Dissociated nystagmus in side gaze. Major symptoms in the diagnosis of an internuclear ophthalmoplegia]
    P Neugebauer
    Klinik und Poliklinik für Hals Nasen Ohren Heilkunde des Klinikums der Universität zu Köln
    HNO 52:623-6. 2004
    ..The lesion is often due to multiple sclerosis, but can also be ischemic, traumatic, neoplastic or inflammatory (e.g. HIV infection)...
  75. ncbi Dorsal midbrain syndrome secondary to a pineocytoma
    D M Allmer
    Dakota Vision, Rapid City, South Dakota, USA
    Optometry 72:234-8. 2001
    ..Pineal gland tumors are rare tumors that show a predilection for males. The specific tumor reported herein, a pineocytoma, shows no gender predilection and is most common in mid- to late adulthood...
  76. ncbi Nystagmus
    I Gottlob
    Department of Ophthalmology, University of Leicester, UK
    Curr Opin Ophthalmol 11:330-5. 2000
    This report reviews the recent contributions to the field of pathologic nystagmus. The classification and nomenclature of nystagmus with onset in infancy is controversial...
  77. ncbi Prospects for treating acquired pendular nystagmus with servo-controlled optics
    J S Stahl
    Department of Neurology, Case Western Reserve University, Cleveland Veterans Affairs Medical Center, Ohio, USA
    Invest Ophthalmol Vis Sci 41:1084-90. 2000
    ..To determine whether a device featuring electronically controlled motor-driven prisms can reduce oscillopsia and improve acuity in patients with acquired pendular nystagmus (APN)...
  78. ncbi Periodic alternating nystagmus and rebound nystagmus in spinocerebellar ataxia type 6
    Takao Hashimoto
    Third Department of Medicine, Shinshu University School of Medicine, Asahi, Matsumoto, Japan
    Mov Disord 18:1201-4. 2003
    ..They carried the identical mutation (the number of expanded CAG repeat, 24) in the CACNA1A gene. The intrafamilial variability of oculomotor symptoms may be ascribed to factors other than CAG repeat expansion size in SCA6...
  79. ncbi Dissociated eye movements: a clinical study
    Pedro Luiz Mangabeira Albernaz
    Department of Otorhinolaryngology Head and Neck Surgery, Federal University of Sao Paulo, Paulista Medical School, Sao Paulo, Brazil
    Acta Otolaryngol 125:495-8. 2005
    ..Dissociation of eye movements is an important sign of functional or organic lesions of the central vestibular system. Qualitative differences in the movements of each eye appear to be more serious than quantitative differences...
  80. ncbi "Minimized rotational vestibular testing" as a screening procedure detecting vestibular areflexy in deaf children: screening cochlear implant candidates for Usher syndrome type I
    Magnus Teschner
    Department of Otolaryngology, Medical University of Hannover, 30625, Hannover, Germany
    Eur Arch Otorhinolaryngol 265:759-63. 2008
    ..Children with USH I are threatened by progressive reduction of vision. We, therefore, consider USH I children always to be implanted bilaterally with a cochlear implant to maximize the benefit of auditory rehabilitation...
  81. ncbi Vestibular disease in dogs and cats
    John H Rossmeisl
    Neurology and Neurosurgery, Department of Small Animal Clinical Sciences, Virginia Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg, VA 24061, USA
    Vet Clin North Am Small Anim Pract 40:81-100. 2010
    ..Clinical signs of vestibular disease include asymmetric ataxia, head tilt, and pathologic nystagmus. Neuroanatomic localization of observed vestibular signs to either the peripheral or central components of ..
  82. ncbi Sylvian aqueduct syndrome with slit ventricles in shunted hydrocephalus due to adult aqueduct stenosis
    Helen Maroulis
    Department of Neurosurgery, Royal North Shore Hospital, Sydney, Australia
    J Neurosurg 109:939-43. 2008
    ..The authors propose a simple management plan for patients with shunted hydrocephalus who develop SAS...
  83. ncbi Ocular myasthenia mimicking a one-and-a-half syndrome
    F Bandini
    Laboratory of Neuro ophthalmology, Department of Neurological and Visual Sciences, University of Genoa, Italy
    J Neuroophthalmol 21:210-1. 2001
    ..This patient shows that an oculomotor disorder considered a typical pontine lesion may instead be caused by myasthenia gravis, even in the absence of other clinical and electrophysiologic features of neuromuscular deficit...
  84. ncbi Horizontal monocular saccadic failure: an unusual clinically isolated syndrome progressing to multiple sclerosis
    Elliot M Frohman
    Department of Neurology, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75235, USA
    Mult Scler 9:55-8. 2003
    ..Four years later, the subject developed a partial sensory transverse myelitis, confirming clinically definite multiple sclerosis (MS). This paper extends the range of isolated syndromes associated with MS...
  85. ncbi Bilateral pseudo-internuclear ophthalmoplegia in myasthenia gravis
    K Ito
    Department of Otolaryngology, University of Tokyo, Bunkyo ku, Japan
    ORL J Otorhinolaryngol Relat Spec 59:122-6. 1997
    ..Dissociated nystagmus and monocular overshoot might be the results of central compensation...
  86. ncbi Two hypothetical nystagmus procedures: augmented tenotomy and reattachment and augmented tendon suture (Sans tenotomy)
    Louis F Dell'Osso
    Daroff Dell Osso Ocular Motility Laboratory, Louis Stokes Cleveland Department of Veterans Affairs Medical Center and CASE Medical School, Cleveland, Ohio 44106, USA
    J Pediatr Ophthalmol Strabismus 46:337-44. 2009
    ....
  87. ncbi Diagnostic value of vestibulo-ocular reflex parameters in the detection and characterization of labyrinthine lesions
    Raphael Maire
    Clinic of Otolaryngology, Head and Neck Surgery, University Hospital Lausanne, Switzerland
    Otol Neurotol 27:535-41. 2006
    ..To evaluate the power of various parameters of the vestibulo-ocular reflex (VOR) in detecting unilateral peripheral vestibular dysfunction and in characterizing certain inner ear pathologies...
  88. ncbi Nystagmus
    M L Moster
    Department of Neurosensory Sciences, Albert Einstein Medical Center, Philadelphia, Pennsylvania, USA
    Ophthalmol Clin North Am 14:205-15. 2001
    ..Additionally, if there is oscillopsia or blurred vision, treatment of the nystagmus itself may be warranted. Possible treatments include medication, optical manipulations, and surgery...
  89. ncbi The number of procedures required to eliminate positioning nystagmus in benign paroxysmal positional vertigo
    Ricardo Schaffeln Dorigueto
    Program of Post graduation in Otorhinolaryngology and Head and Neck Surgery, Federal University of Sao Paulo Escola Paulista de Medicina, Otorhinolaryngology
    Braz J Otorhinolaryngol 71:769-75. 2005
    ....
  90. doi Paraneoplastic downbeat nystagmus
    Miguel Bussière
    Can J Ophthalmol 43:243-5. 2008
  91. ncbi Oscillopsia in "inverse latent" infantile nystagmus syndrome
    Larry A Abel
    Department of Optometry and Vision Sciences, University of Melbourne, Melbourne, Victoria, Australia
    Optom Vis Sci 84:1017-23. 2007
    ..We have attempted to explain this and to identify an intervention that preserves binocular vision while maximizing perceptual stability...
  92. ncbi Intractable benign paroxysmal positioning vertigo: long-term follow-up and inner ear abnormality detected by three-dimensional magnetic resonance imaging
    Arata Horii
    Department of Otolaryngology, Suita Municipal Hospital, Osaka University School of Medicine, Osaka, Japan
    Otol Neurotol 31:250-5. 2010
    ..To investigate the occurrence rate, prognosis, and inner ear abnormality in intractable benign paroxysmal positioning vertigo (BPPV)...
  93. ncbi Strategies to distinguish benign paroxysmal positional vertigo from rotational vertebrobasilar ischemia
    Katherine D Heidenreich
    Division of Otology and Neurotology, Department of Otolaryngology Head and Neck Surgery, University of Michigan Health System, Ann Arbor, MI 48109 5312, USA
    Ann Vasc Surg 24:553.e1-5. 2010
    ..Treatment of her BPPV led to complete resolution of her symptoms. A succinct overview of this common otologic disorder is provided, and strategies to help distinguish it from RVBI are discussed...
  94. ncbi [Reduced vision in Wernicke's syndrome with symptoms of nystagmus]
    Michael E Lindholt
    Holstebro Centralsygehus, Øjenafdelingen
    Ugeskr Laeger 168:1451-2. 2006
    ..It should be considered in the differential diagnosis of bilateral ophthalmoplegia even in the absence of altered mental status...
  95. ncbi Rotational vertigo associated with parietal cortical infarction
    Masaki Naganuma
    Stroke Center, Saiseikai Kumamoto Hospital, Chikami 5 3 1, Kumamoto 861 4193, Japan
    J Neurol Sci 246:159-61. 2006
    ..We suggest that this patient's vertigo was due to her parietal cortical infarction...
  96. ncbi Endoscopic third ventriculotomy improves parkinsonism following a ventriculo-peritoneal shunt in a patient with non-communicating hydrocephalus secondary to idiopathic aqueduct stenosis
    A Hashizume
    Department of Neurology, Nagoya University Graduate School of Medicine, Nagoya, Japan
    J Neurol Sci 309:148-50. 2011
    ..A neural network formation known as the 'cortico-basal ganglia loop,' which intimately connects the frontal lobe with the basal ganglia, is possibly associated with the Parkinsonism observed in our patient...
  97. ncbi Retrolabyrinthine approach for surgical placement of auditory brainstem implants in children
    Ricardo Ferreira Bento
    Division of Otorhinolaryngology, University of Sao Paulo Medical School, Brazil
    Acta Otolaryngol 132:462-6. 2012
    ..The extended retrolabyrinthine approach (RLA) is a safe and reliable approach for auditory brainstem placement in children. The surgical landmarks to reach cochlear nucleus are adequately exposed by this approach...
  98. ncbi Late onset cerebellar cortical degeneration in a koala
    M Kuwamura
    Osaka Prefecture University, Sakai, Japan
    Aust Vet J 87:342-4. 2009
    ..The very late onset and slow progression of the cerebellar cortical degeneration in this case is particularly interesting and appears to be the first report in the koala...
  99. pmc Upbeat-torsional nystagmus and contralateral fourth-nerve palsy due to unilateral dorsal ponto mesencephalic lesion
    Matthew J Thurtell
    Department of Neurology, University Hospitals Case Medical Center, Cleveland, Ohio, USA
    Ann N Y Acad Sci 1164:476-8. 2009
    ..These observations suggest that, in humans, excitatory upward-torsional eye movement signals from the anterior semicircular canals could be partly conveyed to the midbrain by the brachium conjunctivum...
  100. ncbi Sleep position and laterality of benign paroxysmal positional vertigo
    S G Korres
    ENT Department of Hippokration Hospital, National University of Athens, Greece
    J Laryngol Otol 122:1295-8. 2008
    ....
  101. ncbi [Visual and central oculomotor disorders in patients with acquired immunodeficiency syndrome]
    C Roig
    , Hospital de la Santa Creu i Sant Pau, , Barcelona,
    Rev Neurol 24:1597-604. 1996
    ..These changes are seen in all ADC patients, in a large proportion of those without dementia and also in asymptomatic carriers, suggesting that oculography may be useful for prognosis...

Research Grants20

  1. Mechanism of Opiate Induced Audiovestibular Dysfunction
    Gail Ishiyama; Fiscal Year: 2006
    ....
  2. MUTATIONS IN CALCIUM CHANNELS CAUSING VERTIGO AND ATAXIA
    Joanna Jen; Fiscal Year: 2002
    ..The further relevance of this work to the more common basilar migraine and Meniere's syndrome is emphasized by the overlapping symptoms of vertigo and ataxia in the group of patients that we propose to study. ..
  3. Pathobiology of Retinal Vasculopathy with Cerebal Leukodystrophy (RVCL)
    Joanna C Jen; Fiscal Year: 2010
    ..abstract_text> ..
  4. THE GENETIC & FUNCTIONAL ANATOMICAL BASIS OF HGPPS
    Joanna Jen; Fiscal Year: 2009
    ..Understanding the anatomical and molecular basis of HGPPS will provide insight into the genetically programmed neurodevelopment of the conjugate horizontal gaze center and other cranial nuclei in the brainstem. ..
  5. Evalution of Vestibular Function in Meniere's Disease
    John Carey; Fiscal Year: 2009
    ..Comparisons of angular and translational VOR deficits after intratympanic gentamicin should demonstrate whether or not the utricle is less susceptible than the semicircular canals to intratympanic gentamicin. ..
  6. Genetics of Familial Episodic Ataxia
    Joanna C Jen; Fiscal Year: 2010
    ..Insights gained from the study will lead to improved diagnosis and treatment of familial episodic ataxia and the more common episodic vertigo syndromes. ..
  7. International Conference on Episodic Ataxia Syndromes
    Joanna Jen; Fiscal Year: 2005
    ..abstract_text> ..
  8. VESTIBULAR EFFECTS OF INTRATYMPANIC GENTAMICIN
    John Carey; Fiscal Year: 2005
    ..Johns Hopkins is uniquely suited to this training because it has a core group devoted to vestibular research, and the mentor's laboratory has successfully used all of the techniques required. ..
  9. Vestibular Recovery after Intratympanic Gentamicin
    John Carey; Fiscal Year: 2004
    ..Furthermore, the mechanisms of vestibular recovery may help us understand the potential for the inner ear to recover from a variety of injuries. ..
  10. PEDIATRIC LOW VISION
    WILLIAM GOOD; Fiscal Year: 2002
    ..Do strabismus and anisometropia affect different visual functions differentially? Is the combination of risk-factors more amblyogenic? ..
  11. Perceptual encoding and imagery in prosopagnosia
    Jason Barton; Fiscal Year: 2008
    ..From our prior work, we hypothesize that covert or unconscious recognition is the residual product of a partially damaged face network in the brain. We propose a functional imaging experiment to test this hypothesis. ..
  12. Vestibulocerebellar function in channelopathy mutants
    John Stahl; Fiscal Year: 2004
    ..Thus, the insights into normal cerebellar function generated by this study should also advance our understanding of mechanisms of heritable neurological disease. ..
  13. EARLY TMT RETINOPATHY OF PREMATURITY HEADQUARTER GRANT
    WILLIAM GOOD; Fiscal Year: 2008
    ..Outcome will be determined at a 6 month post-term ophthalmologic examination and at a 9 month post-term visual assessment examination. ..
  14. Preceptual Stability and Nystagmus
    HAROLD BEDELL; Fiscal Year: 2004
    ..abstract_text> ..
  15. MANAGEMENT OF ADAPTATION TO ALTERED SENSORIMOTOR STATES
    Helen Cohen; Fiscal Year: 2003
    ..abstract_text> ..
  16. The Effects of Prematurity on Visual Development
    WILLIAM GOOD; Fiscal Year: 2008
    ..A comparison of head ultrasound and DTI findings will demonstrate whether DTI should replace ultrasound for the diagnosis of neurological injury in the newborn nursery. [unreadable] [unreadable]..
  17. TREATMENTS FOR BENIGN PAROXYSMAL POSITIONAL VERTIGO
    Helen Cohen; Fiscal Year: 2008
    ..4. Determine the influence of rhinosinusitis. A) Determine the prevalence of rhinosinusitis in patients with BPPV. B) Determine if the presence of rhinosinusitis affects severity of symptoms or response to treatment. ..
  18. Diseases of the Vestibular System
    Robert Baloh; Fiscal Year: 2006
    ..abstract_text> ..
  19. DIZZINESS IN OLDER PEOPLE
    Robert Baloh; Fiscal Year: 2006
    ..By continuing this longitudinal study of carefully studied older patients and controls, our multidisciplinary research team is in a good position to achieve our goals. ..
  20. VESTIBULAR INFLUENCES ON SPATIAL ORIENTATION
    Richard Lewis; Fiscal Year: 2008
    ..abstract_text> ..