Genomes and Genes
Summary: An abnormal triangular fold of membrane in the interpalpebral fissure, extending from the conjunctiva to the cornea, being immovably united to the cornea at its apex, firmly attached to the sclera throughout its middle portion, and merged with the conjunctiva at its base. (Dorland, 27th ed)
Publications302 found, 100 shown here
- Prevalence and risk factors of pterygium and pinguecula: the Tehran Eye StudyA Fotouhi
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
Eye (Lond) 23:1125-9. 2009To determine the prevalence and causes of pterygium and pinguecula in the population of Tehran in 2002.
- Acute scleral thinning after pterygium excision with intraoperative mitomycin C: a case report of scleral dellen after bare sclera technique and review of the literatureYi Yu Tsai
Department of Ophthalmology, China Medical College Hospital, Taichung, Taiwan
Cornea 21:227-9. 2002To describe a patient with scleral dellen after pterygium excision with intraoperative mitomycin C.
- The results of amniotic membrane transplantation for primary pterygium compared with conjunctival autograftNapaporn Tananuvat
Department of Ophthalmology, Chiang Mai University, Chiang Mai, Thailand
Cornea 23:458-63. 2004To study the efficacy and safety of amniotic membrane transplantation as an adjunctive therapy after surgical excision of primary pterygium and to compare the clinical outcome with that of conjunctival autograft.
- Angiogenesis in pterygium: study of microvessel density, vascular endothelial growth factor, and thrombospondin-1M Aspiotis
Department of Ophthalmology, University of Ioannina, Ioannina, Epirus, Greece
Eye (Lond) 21:1095-101. 2007This retrospective study aims to elucidate the role of angiogenesis in the pathogenesis of pterygium. We evaluated microvessel density (MVD), and expression of vascular endothelial growth factor (VEGF) and thrombospondin-1 (TSP-1).
- Pathogenetic mechanisms and treatment options for ophthalmic pterygium: trends and perspectives (Review)Efstathios T Detorakis
Department of Ophthalmology, University Hospital of Heraklion, and Laboratory of Virology, Medical School, University of Crete, 71110 Heraklion, Crete, Greece
Int J Mol Med 23:439-47. 2009b>Pterygium is a fibrovascular lesion of the ocular surface that can display an aggressive clinical behavior and, occasionally, threaten vision...
- Fibrin glue versus sutures for conjunctival autografting in pterygium surgery: a prospective comparative studyA Karalezli
Department of Ophthalmology, Baskent University School of Medicine, Ankara, Turkey
Br J Ophthalmol 92:1206-10. 2008To compare the use of fibrin glue versus sutures for fixating conjunctival autografts in patients undergoing pterygium excision.
- Oxidative stress in pterygium: relationship between p53 and 8-hydroxydeoxyguanosineMaria Teresa Perra
Department of Cytomorphology, University of Cagliari, Monserrato, Italy
Mol Vis 12:1136-42. 2006..is known to cause oxidative DNA damage and is thought to be a major factor implicated in the pathogenesis of pterygium, a benign invasive lesion of the bulbar conjunctiva...
- Ophthalmic pterygium: a stem cell disorder with premalignant featuresJeanie Chui
Inflammation and Infection Research Centre, School of Medical Sciences, University of New South Wales, Sydney, Australia
Am J Pathol 178:817-27. 2011..One hundred pterygium specimens were histopathologically reviewed and selected cases were immunohistochemically assessed to confirm ..
- Pterygium: prevalence, demography and risk factorsS M Saw
National University of Singapore Department of Community, Occupational and Family Medicine Singapore
Ophthalmic Epidemiol 6:219-28. 1999b>Pterygium is not just a degenerative disease, but may be a proliferative disorder of the ocular surface. The etiology of pterygia has intrigued researchers for centuries...
- Prevalence and risk factors of pterygium in a southwestern island of Japan: the Kumejima StudyHiroki Shiroma
Department of Ophthalmology, University of the Ryukyus Faculty of Medicine, Okinawa, Japan
Am J Ophthalmol 148:766-771.e1. 2009To determine the prevalence and risk factors for pterygium in a Japanese population aged 40 years or older on Kumejima Island, Japan.
- The roles of T-lymphocyte subpopulations (CD4 and CD8), intercellular adhesion molecule-1 (ICAM-1), HLA-DR receptor, and mast cells in etiopathogenesis of pterygiumUmit Beden
Ophthalmology Department, Kars State Hospital, Kars, Turkey
Ocul Immunol Inflamm 11:115-22. 2003..We wished to explore the effects of inflammatory cells and mediators such as T-lymphocyte subpopulations (CD4 and CD8), mast cells, intercellular adhesion molecule-1 (ICAM-1), and HLA-DR receptors on pterygium development.
- The prevalence and risk factors for pterygium in an adult Chinese population in Singapore: the Tanjong Pagar surveyT Y Wong
Singapore National Eye Centre and Eye Research Institute, 11 Third Hospital Ave, Singapore 168751, Singapore
Am J Ophthalmol 131:176-83. 2001PURPOSE: To determine the prevalence and risk factors for pterygium in the Chinese population of Singapore...
- Epidemiology of pterygium in aged rural population of Beijing, ChinaQing feng Liang
Beijing Institute of Ophthalmology Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing 100005, China
Chin Med J (Engl) 123:1699-701. 2010b>Pterygium is a common ophthalmic disease and an important public health problem. It may be affected by many factors such as age, gender, ultraviolet radiation exposure, and time spent outdoors...
- UVB-mediated induction of interleukin-6 and -8 in pterygia and cultured human pterygium epithelial cellsNick Di Girolamo
Inflammation Research Unit, School of Medical Sciences, Department of Pathology, Faculty of Medicine, University of New South Wales, Sydney, Australia
Invest Ophthalmol Vis Sci 43:3430-7. 2002..The hypothesis tested in the current study is that UV radiation modulates the expression of interleukin (IL)-6 and -8, which could promote the neovascularization and chronic inflammation regularly observed in pterygia...
- Intraoperative daunorubicin versus conjunctival autograft in primary pterygium surgerySubhash Dadeya
Department of Ophthalmology, Safdarjung Hospital, New Delhi, India
Cornea 21:766-9. 2002To evaluate the safety and efficacy of intraoperative daunorubicin during a bare sclera procedure in primary pterygium surgery and to compare with conjunctival autograft.
- Prevalence of and racial differences in pterygium: a multiethnic population study in AsiansMarcus Ang
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Republic of Singapore
Ophthalmology 119:1509-15. 2012To describe the prevalence and risk factors of pterygium in a multiethnic Asian population and to examine racial differences.
- Prevalence of pterygium in Latinos: Proyecto VERS West
Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, Johns Hopkins University, Baltimore, MD 21287, USA
Br J Ophthalmol 93:1287-90. 2009b>Pterygium is a common corneal eye condition that can be disfiguring and may require surgery to avoid loss of vision. There are no population-based data on the prevalence or on risk factors among Latinos.
- Pterygium in an aged Mongolian population: a population-based study in ChinaJ Lu
Institute of Developmental Biology, Lanzhou University, China
Eye (Lond) 23:421-7. 2009To determine the prevalence and identify associated risk factors for pterygium in an elderly Mongolian population at high altitude in Henan County, China.
- The prevalence of and risk factors for pterygium in an urban Malay population: the Singapore Malay Eye Study (SiMES)H Cajucom-Uy
Corneal and External Eye Disease Service, Singapore National Eye Centre, Singapore
Br J Ophthalmol 94:977-81. 2010To determine the prevalence and risk factors for pterygium in the adult Malay population of Singapore.
- Quantitative analysis of regular and irregular astigmatism induced by pterygiumA Tomidokoro
Department of Ophthalmology, Omiya Red Cross Hospital, Saitama, Japan
Cornea 18:412-5. 1999To quantitatively evaluate the influence of pterygium and its removal surgery on both regular and irregular corneal astigmatism.
- The science of pterygiaJ C Bradley
Department of Ophthalmology and Vision Sciences, University of California Davis, Sacramento, California, USA
Br J Ophthalmol 94:815-20. 2010b>Pterygium is an ocular surface disease of humans attributed to chronic ultraviolet-B exposure. Clinically, the condition involves invasive centripetal growth with associated inflammation and neovascularisation...
- Increased oxidative DNA damage, 8-hydroxydeoxy- guanosine, in human pterygiumH C Kau
Department of Ophthalmology, Taoyuan Veterans Hospital, Taoyuan, Taiwan
Eye (Lond) 20:826-31. 2006Chronic exposure to ultraviolet (UV) light is a widely accepted aetiological factor in the development of pterygium. UV radiation may induce production of reactive oxygen species via photosensitized oxidation, thus causing oxidative ..
- Differential expression of matrix metalloproteinases and their tissue inhibitors at the advancing pterygium headN Di Girolamo
Inflammation Research Unit, School of Pathology, University of New South Wales, Australia
Invest Ophthalmol Vis Sci 41:4142-9. 2000..The purpose of this study was to determine the expression of matrix metalloproteinases (MMPs) and tissue inhibitors of MMPs (TIMPs) at the advancing pterygium edge.
- Active matrilysin (MMP-7) in human pterygia: potential role in angiogenesisN Di Girolamo
Inflammation Research Unit, School of Pathology, University of New South Wales, Sydney, New South Wales, Australia
Invest Ophthalmol Vis Sci 42:1963-8. 2001..The purpose of this study was to determine the cellular distribution and activation status of matrilysin (MMP-7) in pterygia...
- Angiogenesis in pterygium: morphometric and immunohistochemical studyArie L Marcovich
Department of Ophthalmology, Kaplan Medical Center, Rehovot, Israel
Curr Eye Res 25:17-22. 2002To evaluate the role of angiogenesis in the pathogenesis of pterygium by comparing the expression of von-Willebrand factor (vWF) and vascular endothelial growth factor (VEGF) in pterygium, and in normal superior bulbar conjunctiva.
- Effect of TIMP-1 and MMP in pterygium invasionYi Yu Tsai
Department of Ophthalmology, China Medical University Hospital, Taichung, Taiwan
Invest Ophthalmol Vis Sci 51:3462-7. 2010..Therefore, the purpose of this study was to determine the role of MMP-9, MMP-10, and TIMPs in pterygium formation and progression. METHODS...
- Current concepts and techniques in pterygium treatmentLeonard P K Ang
Singapore National Eye Centre, Singapore
Curr Opin Ophthalmol 18:308-13. 2007b>Pterygium is a common ocular disorder in many parts of the world. At present, there is a wide variety of surgical methods but very few clinical guidelines on the optimal treatment of primary or recurrent pterygium...
- Subconjunctival bevacizumab injection for corneal neovascularization in recurrent pterygiumIrit Bahar
Department of Ophthalmology, Toronto Western Hospital, University of Toronto, Toronto, Ontario, Canada
Curr Eye Res 33:23-8. 2008..We report on the use of subconjunctival bevacizumab on corneal vessel density in recurrent pterygia...
- Oxidative DNA damage in pterygiumYi Yu Tsai
Department of Ophthalmology, China Medical University Hospital and Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan
Mol Vis 11:71-5. 2005..If pterygium is related to UV, we surmised oxidative stress exists in pterygium...
- In vivo confocal microscopic evaluation of morphologic changes and dendritic cell distribution in pterygiumYan Wang
Department of Ophthalmology, Eye and ENT Hospital of Fudan University, Shanghai, China
Am J Ophthalmol 150:650-655.e1. 2010To observe morphologic changes and the distribution of dendritic cells in pterygium using in vivo laser scanning confocal microscopy (LSCM).
- Prevalence of pinguecula and pterygium in a general population in SpainE Viso
Department of Ophthalmology, Complexo Hospitalario de Pontevedra, Pontevedra, Spain
Eye (Lond) 25:350-7. 2011To determine the prevalence of pinguecula and pterygium and to investigate their associations in a general adult population in North-Western Spain.
- Expression of p27(KIP1) and cyclin D1, and cell proliferation in human pterygiumSatoru Kase
Department of Ophthalmology, Sapporo Social Insurance General Hospital, Sapporo, Japan
Br J Ophthalmol 91:958-61. 2007The pterygium is a growth onto the cornea of fibrovascular tissue that is continuous with the conjunctiva, whereas the mechanisms of cell proliferation in pterygium epithelium are unknown.
- Ocular surface disorder in pterygium: role of conjunctival impression cytologyRanjana Bandyopadhyay
Department of Pathology, Medical College, Kolkata 700 073, India
Indian J Pathol Microbiol 53:692-5. 2010To study ocular surface abnormalities in patients with pterygium, conjunctival impression cytology was explored as a tool for the assessment of the cytological changes.
- Recurrent pterygium surgery using pterygium extended removal followed by extended conjunctival transplant: recurrence rate and cosmesisLawrence W Hirst
University of Queensland and Queensland Eye Institute, Brisbane, Australia
Ophthalmology 116:1278-86. 2009To assess the rate of recurrence, complications, and cosmesis after recurrent pterygium removal with P.E.R.F.E.C.T. for PTERYGIUM (Pterygium Extended Removal Followed by Extended Conjunctival Transplant).
- Growth factor expression in ophthalmic pterygia and normal conjunctivaEfstathios T Detorakis
Department of Ophthalmology, University Hospital of Heraklion, 71110 Heraklion, Crete, Greece
Int J Mol Med 25:513-6. 2010The expression of growth factors in ophthalmic pterygium and phenotypically normal conjunctiva was examined and correlated with the clinical findings...
- Topical bevacizumab eyedrops for limbal-conjunctival neovascularization in impending recurrent pterygiumPei Chang Wu
Department of Ophthalmology, Chang Gung Memorial Hospital, Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
Cornea 28:103-4. 2009To report a case of impending recurrent pterygium treated with topical bevacizumab eyedrops.
- Prevalence of and factors associated with pterygium in adult Chinese: the Beijing Eye StudyKe Ma
Beijing Institute of Ophthalmology, Beijing Tongren Hospital, Capital Medical University, Beijing, China
Cornea 26:1184-6. 2007..To evaluate the prevalence of pterygia and its associated factors in an adult Chinese population of Greater Beijing...
- Pterygium and genetic polymorphisms of the DNA repair enzymes XRCC1, XPA, and XPDChun Chi Chiang
Department of Ophthalmology, China Medical University Hospital, Taichung, Taiwan
Mol Vis 16:698-704. 2010b>Pterygium is an ultraviolet (UV) related disease. UV radiation can produce DNA damage, which is repaired by the DNA repair systems...
- The presence of T-lymphocyte subpopulations (CD4 and CD8) in pterygia: evaluation of the inflammatory responseRichard M Awdeh
Department of Ophthalmology, Albert Eye Research Institute, Duke University Eye Center, Durham, NC 27710, USA
Adv Ther 25:479-87. 2008The aim of our study was to confirm the presence of inflammatory T-lymphocyte subpopulations (CD4 and CD8) in pterygium specimens with regards to clinical severity...
- Recurrence rate using fibrin glue-assisted ipsilateral conjunctival autograft in pterygium surgery: 2-year follow-upVincenzo Sarnicola
Misericordia Hospital, Grosseto, Italy
Cornea 29:1211-4. 2010To determine the recurrence rate after pterygium excision with ipsilateral conjunctival autograft using fibrin glue.
- Evaluation of conjunctival graft thickness after pterygium surgery by anterior segment optical coherence tomographyAhmad Kheirkhah
Farabi Eye Hospital, Eye Research Center, Tehran University of Medical Sciences, Tehran, Iran
Curr Eye Res 36:782-6. 2011To evaluate changes in thickness of the conjunctival graft after pterygium surgery by anterior segment optical coherence tomography (AS-OCT).
- Comparison of pterygium recurrence rates after limbal conjunctival autograft transplantation and other techniques: meta-analysisKangkeng Zheng
Joint Shantou International Eye Center, Shantou University, Shantou, China
Cornea 31:1422-7. 2012Meta-analysis to compare pterygium surgery outcomes using limbal conjunctival autograft (LCAG) and other techniques.
- The prevalence of and risk factors associated with pterygium in a rural adult Chinese population: the Handan Eye StudyLan Ping Sun
Handan Eye Hospital, Hebei Province, China
Ophthalmic Epidemiol 20:148-54. 2013To describe the prevalence and risk factors for pterygium in a rural adult Chinese population.
- Prevalence of and risk factors for pterygium in rural adult chinese populations of the Bai nationality in Dali: the Yunnan Minority Eye StudyHua Zhong
Department of Ophthalmology, the First Affiliated Hospital of Kunming Medical University, Kunming, People s Republic of China
Invest Ophthalmol Vis Sci 53:6617-21. 2012The purpose of the study was to describe the prevalence, severity, and associated risk factors for pterygium in a population-based sample of rural residents of the Bai minority population in rural Dali, China.
- Investigation of oxidative stress in pterygium tissueMehmet Balci
Department of Ophthalmology, Abdurrahman Yurtaslan Oncological Training and Research Hospital, Ankara, Turkey
Mol Vis 17:443-7. 2011To investigate changes in the oxidant-antioxidant system in pterygium tissue.
- Prevalence and associated factors for pterygium in a rural adult population (the Southern Harbin Eye Study)Zhijian Li
Department of Ophthalmology, First Affiliated Hospital, Harbin Medical University, Harbin, China
Cornea 32:806-9. 2013To estimate the prevalence of pterygium and identify associated risk factors in a Southern Harbin population at low altitude in a cold climate.
- Immunohistochemical analysis of angiotensin converting enzyme in Sardinian pterygiumPaolo Demurtas
Department of Cytomorphology, University of Cagliari Medical School, Cagliari, Italy
Histol Histopathol 28:759-66. 2013b>Pterygium is a common ocular surface disorder characterized by excessive cell proliferation, inflammation, fibrosis, angiogenesis and extracellular matrix remodeling...
- Immunohistochemical detection of Hsp90 and Ki-67 in pterygiumRoberto Sebastiá
Department of Ophthalmology, Universitary Hospital Federal Fluminense University, Rio de Janeiro, Brazil
Diagn Pathol 8:32. 2013To examine the immunohistochemical expression of heat shock protein 90 (Hsp90) and Ki-67 protein in human pterygium.
- Risk factors associated with pterygium and its subtypes in Korea: the Korean National Health and Nutrition Examination Survey 2008-2010Tyler Hyung Taek Rim
Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Seoul, Korea
Cornea 32:962-70. 2013To assess the sociodemographic and health-related risk factors associated with pterygium and its subtypes in Korea.
- Prevalence of pterygium in a population in Northern Japan: the Locomotive Syndrome and Health Outcome in Aizu Cohort StudyTakatoshi Tano
Department of Ophthalmology, Juntendo University School of Medicine, Tokyo, Japan
Acta Ophthalmol 91:e232-6. 2013The aim of the study was to determine the prevalence and risk factors for pterygium in a population aged 40-74 years in Fukushima Prefecture, Japan.
- Overexpression of peroxiredoxin 2 in pterygium. A proteomic approachV M Bautista-de Lucio
Microbiology and Ocular Proteomics, Research Unit, Institute of Ophthalmology Fundación de Asistencia Privada Conde de Valenciana, Chimalpopoca, 14 Colonia Obrera, 06800 Mexico City, Mexico
Exp Eye Res 110:70-5. 2013b>Pterygium is one of the most frequent pathologies in ophthalmology, and is a benign, fibrovascular lesion originating from the bulbar conjunctiva...
- Comparison of conjunctival autograft with amniotic membrane transplantation for pterygium surgery: surgical and cosmetic outcomeCem Kucukerdonmez
Baskent University Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey
Cornea 26:407-13. 2007..clinical results of conjunctival autograft and amniotic membrane transplantation (AMT) for primary and recurrent pterygium excision...
- Comparison of fibrin glue versus suture for conjunctival autografting in pterygium surgery: a meta-analysisHong wei Pan
Department of Ophthalmology, The First Affiliated Hospital of Jinan University, Guangzhou, China
Ophthalmology 118:1049-54. 2011To evaluate the safety and clinical efficacy of fibrin glue in pterygium surgery with conjunctival autografting.
- Pterygium in Tibetans: a population-based study in ChinaPeng Lu
Ophthalmology Department, West China Hospital, Sichuan University, Chengdu, Sichuan Province, China
Clin Experiment Ophthalmol 35:828-33. 2007To describe the prevalence and to identify associated risk factors for pterygium in a Tibetan population at high altitude in Zeku County, China.
- Amniotic membrane transplantation with conjunctival autograft for recurrent pterygiumJun Shimazaki
Department of Ophthalmology, Tokyo Dental College, Chiba, Japan
Ophthalmology 110:119-24. 2003To study the effect of amniotic membrane transplantation (AMT) combined with either limbal autograft transplantation (LAT) or conjunctival autograft transplantation (CAT) in recurrent pterygium.
- Efficacy of topical bevacizumab for inhibiting growth of impending recurrent pterygiumMohammad Reza Fallah
Department of Ophthalmology, School of Medicine, Medical Sciences, Tehran University, Tehran, Iran
Curr Eye Res 35:17-22. 2010To evaluate clinical outcome(s) and complication(s) of topical bevacizumab (avastin) in patients with impending recurrent pterygium.
- Phase I study of subconjunctival ranibizumab in patients with primary pterygium undergoing pterygium surgeryAnat Galor
Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, Florida 33136, USA
Am J Ophthalmol 149:926-931.e2. 2010To evaluate the safety and tolerability of ranibizumab given via subconjunctival injection in patients with primary pterygium undergoing pterygium surgery with autograft placement.
- Preliminary results of subconjunctival bevacizumab in primary pterygium excisionMohammad Reza Razeghinejad
Department of Ophthalmology and Poostchi Ophthalmic Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
Ophthalmic Res 43:134-8. 2010To evaluate the efficacy of subconjunctival bevacizumab as an adjunctive therapy for primary pterygium surgery.
- Subconjunctival bevacizumab immediately after excision of primary pterygium: the first clinical trialAbdollah Shenasi
Department of Ophthalmology, Nikookari Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
Cornea 30:1219-22. 2011To investigate the effect of subconjunctival bevacizumab immediately after excision of primary pterygium.
- Treatment of pterygiumIsyaku Mohammed
Department of Ophthalmology, Aminu Kano Teaching Hospital, Kano, Nigeria
Ann Afr Med 10:197-203. 2011The treatment of ocular pterygium has been subjected to the development and application of various new strategies in the last few years...
- Corneo-conjunctival autograft transplantation for pterygium surgeryEric Frau
Institute Gustave Roussy, Villejuif, France
Acta Ophthalmol Scand 82:59-63. 2004To evaluate the efficacy of surgical management of pterygium with corneo-conjunctival autograft transplantation.
- The Ets-1 transcription factor is involved in pterygial angiogenesisW Naib-Majani
Department of International Medical Education and Development, Bonn, Germany
Anat Histol Embryol 36:107-10. 2007..In contrast, no expression of ets-1 was found in group 2 pterygia. Proto-oncogene ets-1 expression has been shown for the first time in the metaplastic pterygium, an eye tissue of unknown pathogenesis.
- Analysis of pathohistological characteristics of pterygiumBoban Dzunic
Ophthalmology Clinic, Clinical Center, Nis, Serbia
Bosn J Basic Med Sci 10:307-13. 2010b>Pterygium internum (external eye layer) shows great recurrence tendency after surgical removal. Its etiology is still unclear and represents a significant problem...
- A comparative study of tissue glue and vicryl suture for closing limbal-conjunctival autografts and histologic evaluation after pterygium excisionYasemin Ozdamar
Ankara Ulucanlar Eye Research Hospital, Ankara, Turkey
Cornea 27:552-8. 2008To compare clinical and histopathologic outcomes of tissue glue and vicryl suture to attach limbal conjunctival autografts in pterygium surgery.
- Serious corneoscleral complications after pterygium excision with mitomycin CB Safianik
Br J Ophthalmol 86:357-8. 2002
- Bevacizumab and ocular wound healing after primary pterygium excisionMohammad Banifatemi
Department of Ophthalmology, Shiraz University of Medical Sciences, Khalili Hospital, Shiraz, Iran
J Ocul Pharmacol Ther 27:17-21. 2011The aim of this study was to evaluate the effect of subconjunctival bevacizumab on early postoperative wound healing in patients with primary pterygium excision.
- Fibrin glue versus sutures for attaching the conjunctival autograft in pterygium surgery: a prospective observer masked clinical trialS Srinivasan
Department of Ophthalmology, Toronto Western Hospital, Department of Ophthalmology and Vision Sciences, University of Toronto, Toronto, Ontario, Canada
Br J Ophthalmol 93:215-8. 2009To compare the degree of conjunctival autograft inflammation, subconjunctival haemorrhage (SCH) and graft stability following the use of sutures or fibrin glue (FG) during pterygium surgery.
- Scleral melting 16 years after pterygium excision with topical Mitomycin C adjuvant therapyW M Wan Norliza
Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia
Cont Lens Anterior Eye 29:165-7. 2006To report a case of scleral melting noted 16 years after pterygium excision with postoperative adjuvant topical Mitomycin C (MMC).
- Relationship between the morbidity of pterygium and the duration of ultraviolet rays exposure in Sanya, ChinaQi Chang Yan
Department of Ophthalmology, Fourth Affiliated Hospital, China Medical University, Shenyang 110005, China
Chin Med J (Engl) 119:1308-10. 2006
- Preliminary evidence of the presence of lymphatic vessels immunoreactive for D2-40 and Prox-1 in human pterygiumAnca Maria Cimpean
Department of Histology, Victor Babes University of Medicine and Pharmacy, Timisoara, Romania
Oncol Rep 26:1111-3. 2011Human pterygium is a benign fibrovascular outgrowth of the corneo-conjunctival junction, characterized by tissue remodeling, cellular proliferation, angiogenesis and inflammation...
- Low-dose intraoperative mitomycin C as chemoadjuvant for pterygium surgeryH C Cheng
Department of Ophthalmology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, ROC
Cornea 20:24-9. 2001..and safety of low-dose intraoperative mitomycin C (MMC) during bare sclera procedure and to compare the rates of pterygium recurrence between recurrent pterygium patients treated with adjuvant MMC and those reconstructed with a ..
- Decreased pigment epithelium-derived factor and increased vascular endothelial growth factor levels in pterygiaJi Jin
Department of Ophthalmology, The Jinhua Central Hospital, Zhejiang, China
Cornea 22:473-7. 2003..This study compared expression levels of an angiogenic inhibitor, pigment epithelium-derived factor (PEDF), in pterygia with those in normal corneal and conjunctival tissues...
- Pterygium: histological and immunohistochemical aspectsT Golu
Ophthalmology Clinic, Rovinari Hospital, Romania
Rom J Morphol Embryol 52:153-8. 2011b>Pterygium represents a triangular conjunctivo-epithelial overgrowth, proliferating from the bulbar conjunctiva and covering the cornea, causing severe vision loss...
- Connective tissue growth factor in pterygium: simultaneous presence with vascular endothelial growth factor - possible contributing factor to conjunctival scarringGysbert van Setten
St Eriks Eye Clinic, Karolinska Institutet, Polhemsgatan 50, 11282 Stockholm, Sweden
Graefes Arch Clin Exp Ophthalmol 241:135-9. 2003Various growth factors have been detected in pterygium and been associated with its vasculogenesis. The basic pathophysiological mechanisms responsible especially for the fibrotic activity in pterygium are, however, not yet known...
- [Expression of matrix metalloproteinase in human pterygia]Jun Zeng
Department of Ophthalmology, The Second Xiangya Hospital of Central South University, Changsha 410011, China
Yan Ke Xue Bao 20:242-5. 2004To determine the cellular distribution and activation of MMP-2 and MMP-9 in human pterygium.
- Calcium-binding S100 protein expression in pterygiumAndri K Riau
Singapore Eye Research Institute, Singapore
Mol Vis 15:335-42. 2009b>Pterygium is an ocular surface disease of unknown etiology associated with epithelial and fibrovascular outgrowth from the conjunctiva onto the cornea...
- Use of mitomycin C with conjunctival autograft in pterygium surgery in Asian-CanadiansV A Wong
Department of Ophthalmology, University of British Columbia, Vancouver, Canada
Ophthalmology 106:1512-5. 1999..To determine whether using mitomycin C (MMC) before applying conjunctival autograft is better than conjunctival autograft alone in preventing the recurrence of pterygia in an Asian-Canadian population...
- Elevation of human alpha-defensins and S100 calcium-binding proteins A8 and A9 in tear fluid of patients with pterygiumLei Zhou
Singapore Eye Research Institute, Singapore
Invest Ophthalmol Vis Sci 50:2077-86. 2009..In this study the authors determined that the inflammatory nature of pterygium is reflected in the protein components of tears.
- Endothelial progenitor cells in pterygium pathogenesisJ K Lee
Department of Ophthalmology, College of Medicine, Chung Ang University, Seoul, Korea
Eye (Lond) 21:1186-93. 2007The pathogenesis of pterygium is not well known, and controversy exists about the cell origins and the nature of initial trigger required for its development...
- Pterygium in aged population in Doumen County, ChinaKaili Wu
Zhongshan Ophthalmic Center, Sun Yat Sen University, Guangzhou 510060, China
Yan Ke Xue Bao 18:181-4. 2002To estimate the prevalence of pterygium and its influence on visual acuity in aged population of Doumen County, southern China.
- Pterygium in Indonesia: prevalence, severity and risk factorsG Gazzard
Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 139651
Br J Ophthalmol 86:1341-6. 2002To determine prevalence rates, severity, and risk factors for pterygium in adults in provincial Indonesia and to validate a clinical grading scheme in a population based setting.
- Microbial scleritis-experience from a developing countryV Jain
LV Prasad Eye Institute, Hyderabad, India
Eye (Lond) 23:255-61. 2009..The purpose of this article was to study the clinical features, pathogenic organisms, and the outcome in cases of infectious scleritis...
- Expression analysis of human pterygium shows a predominance of conjunctival and limbal markers and genes associated with cell migrationC J Jaworski
Section on Molecular Therapeutics, NEI NIH, Bethesda, MD 20892, USA
Mol Vis 15:2421-34. 2009b>Pterygium is a vision-impairing fibrovascular lesion that grows across the corneal surface and is associated with sunlight exposure...
- Amniotic membrane transplantation after extensive removal of primary and recurrent pterygiaA Solomon
Ocular Surface and Tear Center, Department of Ophthalmology, Bascom Palmer Eye Institute, Miami, FL 33136, USA
Ophthalmology 108:449-60. 2001..CONCLUSIONS: Amniotic membrane transplantation is an effective and safe procedure for pterygium surgery, with a relatively low recurrence rate for both primary and recurrent pterygia...
- The role of substance P in the pathogenesis of pterygiaJeanie Chui
Inflammatory Diseases Research Unit, Department of Pathology, School of Medical Sciences, Faculty of Medicine, University of New South Wales, Sydney, Australia
Invest Ophthalmol Vis Sci 48:4482-9. 2007b>Pterygium is a prevalent ocular surface disorder thought to be triggered by chronic ultraviolet damage to the limbus...
- Prevalence of pterygium and cataract in indigenous populations of the Brazilian Amazon rain forestJ S Paula
School of Medicine of Ribeirao Preto, USP, Brazil
Eye (Lond) 20:533-6. 2006To compare the prevalence of pterygium and cataract in four indigenous populations of the Brazilian Amazonian rain forest (Arawak, Tukano, Maku, and Yanomami) with different ethnic and social behaviour backgrounds.
- Photokeratitis and other phototoxic effects on the cornea and conjunctivaAnthony P Cullen
School of Optometry and Department of Biology, University of Waterloo, Waterloo, Ontario, Canada
Int J Toxicol 21:455-64. 2002..Chronic exposure to solar ultraviolet is a factor in climatic droplet keratopathy and pterygium. Phototoxic compounds or their by-products potentially can reach the cornea from the air, via the tears or ..
- Proliferative effects of heparin-binding epidermal growth factor-like growth factor on pterygium epithelial cells and fibroblastsTimothy M Nolan
Inflammation Research Unit, School of Medical Sciences, University of New South Wales, Sydney, Australia
Invest Ophthalmol Vis Sci 45:110-3. 2004..and chemotactic effects of heparin binding epidermal growth factor-like growth factor (HB-EGF), recently shown to be upregulated by ultraviolet irradiation in pterygium-derived epithelium cells (PECs) and pterygium fibroblasts (PFs).
- A randomized controlled trial of intralesional bevacizumab injection on primary pterygium: preliminary resultsOrapin Enkvetchakul
Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Cornea 30:1213-8. 2011To evaluate the efficacy and safety of intralesional injection of bevacizumab on primary pterygium treatment.
- The effect of pterygium surgery on corneal topographyA Cinal
Yuzuncu Yil University Medical Faculty, Department of Ophthalmology, Van, Turkey
Ophthalmic Surg Lasers 32:35-40. 2001The aim of this prospective randomized clinical study was to evaluate the effect of pterygium surgery on the corneal topography using a computerized corneal topography system.
- Visual acuity and corneal topographic changes related with pterygium surgeryMeltem Yagmur
Department of Ophthalmology, Cukurova University, Faculty of Medicine, Adana, Turkey
J Refract Surg 21:166-70. 2005Applied pre- and postoperative corneal topography outcomes with visual acuities were evaluated to determine the surgical results in pterygium therapy.
- Scleral ulceration after preoperative injection of mitomycin C in the pterygium headMaria A Carrasco
Cornea Service, Wills Eye Hospital, 900 Walnut St, Philadelphia, PA 19107, USA
Arch Ophthalmol 120:1585-6. 2002
- The effect of subconjunctival ranibizumab on primary pterygium: a pilot studyAchilleas Mandalos
2nd Ophthalmology Clinic, Papageorgiou Hospital, Aristotle University, Thessaloniki, Greece
Cornea 29:1373-9. 2010A prospective interventional pilot study was performed to estimate the effect of ranibizumab injection on the clinical and histological picture of primary pterygium.
- Comparison of fibrin glue with sutures for pterygium excision surgery with conjunctival autograftsReece C Hall
Ophthalmology Department, Wellington Hospital, Capital Coast District Health Board, Wellington, New Zealand
Clin Experiment Ophthalmol 37:584-9. 2009To compare pterygium excision conjunctival autograft surgery using Tisseel fibrin glue versus Vicryl sutures.
- Efficacy of intralesional bevacizumab injection in decreasing pterygium sizeMohammad Reza Fallah Tafti
Eye Research Center, Farabi Eye Hospital, Cornea Department, Tehran University of Medical Sciences, Tehran, Iran
Cornea 30:127-9. 2011To evaluate the efficacy of intralesional bevacizumab injection in decreasing size of pterygium.
- Progenitor cells in healing after pterygium excisionJeong Kyu Lee
Department of Ophthalmology, College of Medicine, Chung Ang University, Yongsan gu, Seoul 140 757, Korea
Yonsei Med J 48:48-54. 2007Bone marrow derived progenitor cells were reported to be involved in the pathogenesis of pterygium and have been suggested to be important in angiogenesis and the repair process after tissue damage...
- Comments on using fibrin glue in pterygium surgeryL S Alvarenga
Br J Ophthalmol 89:392; author reply 392. 2005
- Postoperative irradiation for pterygium: retrospective analysis of 1,253 patients from the Osaka University HospitalFumiaki Isohashi
Department of Radiation Oncology, Osaka University Graduate School of Medicine, Osaka, Japan
Strahlenther Onkol 182:437-42. 2006Irradiation of ocular pterygium is considered a valuable treatment supplementation after surgical therapy...
- Randomised controlled study of conjunctival autograft versus amniotic membrane graft in pterygium excisionP Luanratanakorn
Department of Ophthalmology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
Br J Ophthalmol 90:1476-80. 2006To determine whether amniotic membrane can be used as an alternative to conjunctival autograft after pterygium excision.
- Outcome of pterygium surgery: analysis over 14 yearsM Fernandes
Cornea and Anterior Segment Service, LV Prasad Eye Institute, Hyderabad, India
Eye (Lond) 19:1182-90. 2005To report the outcome of pterygium surgery performed at a tertiary eye care centre in South India.
- Long-term follow-up results of lamellar keratoplasty as a treatment for recurrent pterygium and for scleral necrosis induced by beta-irradiationBehrooz Golchin
Sydney Hospital and Sydney Eye Hospital, Sydney, Australia
Cornea 22:612-8. 2003To evaluate the efficacy and safety of lamellar keratoplasty (LK) in the treatment of recurrent pterygium and of scleral necrosis induced by beta-irradiation.
- IDENTIFY LIMBAL STEM CELLS BY CELL SURFACE MARKERSRonald Smith; Fiscal Year: 2005..Stevens-Johnson syndrome, ocul cicatrIcial pemphigoid, contact lenses, severe infection, congenital aniridia, pterygium, herpes simplex epithelial disease contact lens induced keratopathy, neuroparalytic keratitis, drug toxicity, or ..
- PTERYGIUM EVALUATION PROJECTJOHN TWELKER; Fiscal Year: 2001..Dr. Twelker observed, that many of his patients suffered from pterygium, a triangular growth of abnormal tissue which grows from the conjunctiva onto the cornea, often causing blurred ..
- Modular Design Biotherapeutics to Treat Eye and CorneaMichael Burg; Fiscal Year: 2005..Our model proliferative disease is pterygium. In pterygium, corneal cells grow in response to endogenous EGF ligands and obscures vision...
- AMD AND RISK FACTORS IN A HISPANIC POPULATIONSheila West; Fiscal Year: 2003..Such data will advance our understanding of the magnitude of AMD in this ethnic group, and the way in which risk factors relate to AMD in different populations. ..
- TRIAL OF ANTIBIOTICS TO REDUCE RECURRENT TRICHIASISSheila West; Fiscal Year: 2005..abstract_text> ..
- INTERVENTIONS FOR VISUAL LOSS IN NURSING HOME RESIDENTSSheila West; Fiscal Year: 2002..This trial will answer timely questions of the impact on the functional status of the most frail elderly of modest, potentially sustainable inputs into improving the appropriate utilization of eye care services. ..
- Cataract: Health Disparity for Older African-AmericansSheila West; Fiscal Year: 2006..These data will advance the goal of reducing health disparity in visual disability from cataract among older African Americans. ..
- Latino Eye Health: A Communication Strategy for DiabetesSheila West; Fiscal Year: 2007..Improvements in eye care seeking behaviors should help in avoiding visual loss from diabetic retinopathy and macula edema, the leading causes of visual loss in the working age Latino population. [unreadable] [unreadable]..
- Antimicrobial Dental Devices and WaterlinesTED REID; Fiscal Year: 2007..Finally, we will assess the efficacy of the coated tubing in flow cell experiments using Pseudomonas aeruginosa. [unreadable] [unreadable] [unreadable]..
- Who drives safely? Visual/cognitive predictors in EldersSheila West; Fiscal Year: 2008..This study will provide critical data on the interactive role of vision, visual attention, and cognition in changing older persons driving behaviors, and the resulting effect on driver errors and risk of crashes. ..
- Yearly Mass Treatment C. Trachomatis: When Can We Stop?Sheila West; Fiscal Year: 2008..unreadable] [unreadable]..