conjunctivitis

Summary

Top Publications

  1. ncbi Self-inflicted (factitious) conjunctivitis
    Russell Pokroy
    Medical Corps, Israel Defense Force, Israel
    Ophthalmology 110:790-5. 2003
  2. ncbi Management of the red eye for the primary care physician
    Christopher Wirbelauer
    Klinik fur Augenheilkunde, Vivantes Klinikum Neukölln, Berlin, Germany
    Am J Med 119:302-6. 2006
  3. pmc Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome
    Ron A M Fouchier
    Department of Virology and National Influenza Center, Erasmus Medical Center, Dr Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands
    Proc Natl Acad Sci U S A 101:1356-61. 2004
  4. ncbi Outbreak of low pathogenicity H7N3 avian influenza in UK, including associated case of human conjunctivitis
    J S Nguyen-Van-Tam
    United Kingdom Health Protection Agency
    Euro Surveill 11:E060504.2. 2006
  5. ncbi Worldwide time trends for symptoms of rhinitis and conjunctivitis: Phase III of the International Study of Asthma and Allergies in Childhood
    Bengt Bjorksten
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Pediatr Allergy Immunol 19:110-24. 2008
  6. ncbi Epidemiologic study of conjunctivitis-otitis syndrome
    Edouard Bingen
    Service de Microbiologie, Hopital Robert Debre, Paris, France
    Pediatr Infect Dis J 24:731-2. 2005
  7. ncbi Plasminogen deficiency
    V Schuster
    Hospital for Children and Adolescents, Medical Faculty of Leipzig University, Liebigstrasse 20a, Leipzig, Germany
    J Thromb Haemost 5:2315-22. 2007
  8. ncbi The important role of nontypable Streptococcus pneumoniae international clones in acute conjunctivitis
    Nurith Porat
    Pediatric Infectious Disease Unit, Soroka University Medical Center and the Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84101, Israel
    J Infect Dis 194:689-96. 2006
  9. ncbi Gatifloxacin, moxifloxacin, and balofloxacin resistance due to mutations in the gyrA and parC genes of Staphylococcus epidermidis strains isolated from patients with endophthalmitis, corneal ulcers and conjunctivitis
    Gabriel Betanzos-Cabrera
    Area Académica de Nutrición, Instituto de Ciencias de la Salud, Universidad Autonoma del Estado de Hidalgo, Pachuca, Mexico
    Ophthalmic Res 42:43-8. 2009
  10. ncbi Chlamydia trachomatis causing neonatal conjunctivitis in a tertiary care center
    S Kakar
    Department of Microbiology, Deen Dayal Upadhyaya Hospital, New Delhi 110 064, India
    Indian J Med Microbiol 28:45-7. 2010

Research Grants

  1. Enterovirus RNA Translation and Replication
    David J Barton; Fiscal Year: 2013
  2. A Rapid Point-of-care Diagnostic for C. trachomatis STDs
    Richard F Selden; Fiscal Year: 2013
  3. Role of HSV Induced RNA Degradation in Pathogenesis
    David A Leib; Fiscal Year: 2013
  4. Bacteria-Mucin Interactions at the Ocular Surface
    Ilene K Gipson; Fiscal Year: 2012
  5. Encapsidation of Adenovirus DNA
    Michael J Imperiale; Fiscal Year: 2010
  6. Conjunctival Goblet Cell NLRP3 Inflammasome in Ocular Surface Bacterial Infection
    Darlene A Dartt; Fiscal Year: 2013
  7. Diversity and Dynamic Stability of the Ocular Surface Microbiome
    Russell N Van Gelder; Fiscal Year: 2013
  8. Lipid Rafts in Adenoviral Ocular Pathogenesis
    Jaya Rajaiya; Fiscal Year: 2013
  9. THE IMMUNOBIOLOGY OF CORNEAL ALLOGRAFTS
    Jerry Niederkorn; Fiscal Year: 2013
  10. Evaluation of CPAF Mediated Anti-Chlamydial Immunity in the Guinea Pig
    BERNARD PRAGASH ARULANANDAM; Fiscal Year: 2012

Detail Information

Publications224 found, 100 shown here

  1. ncbi Self-inflicted (factitious) conjunctivitis
    Russell Pokroy
    Medical Corps, Israel Defense Force, Israel
    Ophthalmology 110:790-5. 2003
    To describe the diagnosis and management of self-inflicted factitious conjunctivitis in conscripted soldiers.
  2. ncbi Management of the red eye for the primary care physician
    Christopher Wirbelauer
    Klinik fur Augenheilkunde, Vivantes Klinikum Neukölln, Berlin, Germany
    Am J Med 119:302-6. 2006
    ..The most frequent causes of a red eye, such as dry eye, conjunctivitis, keratitis, iritis, acute glaucoma, subconjunctival hematoma, foreign bodies, corneal abrasion, and blunt or ..
  3. pmc Avian influenza A virus (H7N7) associated with human conjunctivitis and a fatal case of acute respiratory distress syndrome
    Ron A M Fouchier
    Department of Virology and National Influenza Center, Erasmus Medical Center, Dr Molewaterplein 50, 3015 GE, Rotterdam, The Netherlands
    Proc Natl Acad Sci U S A 101:1356-61. 2004
    ..Of these 89 patients, 78 presented with conjunctivitis, 5 presented with conjunctivitis and influenza-like illness, 2 presented with influenza-like illness, and 4 ..
  4. ncbi Outbreak of low pathogenicity H7N3 avian influenza in UK, including associated case of human conjunctivitis
    J S Nguyen-Van-Tam
    United Kingdom Health Protection Agency
    Euro Surveill 11:E060504.2. 2006
  5. ncbi Worldwide time trends for symptoms of rhinitis and conjunctivitis: Phase III of the International Study of Asthma and Allergies in Childhood
    Bengt Bjorksten
    Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden
    Pediatr Allergy Immunol 19:110-24. 2008
    ..The increases were more pronounced in the older age group, suggesting that environmental influences on the development of allergy may not be limited to early childhood...
  6. ncbi Epidemiologic study of conjunctivitis-otitis syndrome
    Edouard Bingen
    Service de Microbiologie, Hopital Robert Debre, Paris, France
    Pediatr Infect Dis J 24:731-2. 2005
    We conducted a prospective cross-sectional epidemiologic study of conjunctivitis-otitis syndrome during two 3-week periods of consecutive winters...
  7. ncbi Plasminogen deficiency
    V Schuster
    Hospital for Children and Adolescents, Medical Faculty of Leipzig University, Liebigstrasse 20a, Leipzig, Germany
    J Thromb Haemost 5:2315-22. 2007
    ..Ligneous conjunctivitis is by far the most common clinical manifestation...
  8. ncbi The important role of nontypable Streptococcus pneumoniae international clones in acute conjunctivitis
    Nurith Porat
    Pediatric Infectious Disease Unit, Soroka University Medical Center and the Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva 84101, Israel
    J Infect Dis 194:689-96. 2006
    ..nontypable Streptococcus pneumoniae isolates were found to be highly associated with sporadic cases of acute conjunctivitis (AC)...
  9. ncbi Gatifloxacin, moxifloxacin, and balofloxacin resistance due to mutations in the gyrA and parC genes of Staphylococcus epidermidis strains isolated from patients with endophthalmitis, corneal ulcers and conjunctivitis
    Gabriel Betanzos-Cabrera
    Area Académica de Nutrición, Instituto de Ciencias de la Salud, Universidad Autonoma del Estado de Hidalgo, Pachuca, Mexico
    Ophthalmic Res 42:43-8. 2009
    ..Our aim was to address the quinolone resistance and to explore the resistance mechanism in S. epidermidis strains isolated from ocular infections...
  10. ncbi Chlamydia trachomatis causing neonatal conjunctivitis in a tertiary care center
    S Kakar
    Department of Microbiology, Deen Dayal Upadhyaya Hospital, New Delhi 110 064, India
    Indian J Med Microbiol 28:45-7. 2010
    Chlamydia trachomatis is considered a major aetiological agent of conjunctivitis in newborns...
  11. ncbi Lichen planus and cicatricial conjunctivitis: disease course and response to therapy of 11 patients
    J D Brewer
    Department of Dermatology, Mayo Clinic, Rochester, MN, USA
    J Eur Acad Dermatol Venereol 25:100-4. 2011
    ..Lichen planus is an autoimmune, inflammatory dermatosis of unknown cause that affects the skin and mucous membranes...
  12. pmc Pathogenesis, transmissibility, and ocular tropism of a highly pathogenic avian influenza A (H7N3) virus associated with human conjunctivitis
    Jessica A Belser
    Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Virol 87:5746-54. 2013
    ..findings indicate that the recently isolated North American lineage H7 subtype virus associated with human conjunctivitis is capable of causing severe disease in mice and spreading to naive-contact ferrets, while concurrently ..
  13. pmc External ophthalmomyiasis caused by Oestrus ovis: a rare case report from India
    Anita Pandey
    Department of Microbiology, Subharti Medical College, Meerut, Uttar Pradesh, India
    Korean J Parasitol 47:57-9. 2009
    ..A 25-year-old farmer presented with severe symptoms of conjunctivitis. The larvae, 3 in number, were observed in the bulbar conjunctiva, and following removal the symptoms of eye ..
  14. ncbi Contact lens induced papillary conjunctivitis with silicone hydrogel lenses
    L Sorbara
    Centre for Contact Lens Research, School of Optometry, University of Waterloo, Ontario, Canada
    Cont Lens Anterior Eye 32:93-6. 2009
    To describe the refitting of a soft lens wearer into a silicone hydrogel lens due to neovascularization. This change, in turn, caused contact lens induced papillary conjunctivitis (CLPC) and a further refitting was necessary.
  15. pmc Confirmation of nontypeable Streptococcus pneumoniae-like organisms isolated from outbreaks of epidemic conjunctivitis as Streptococcus pneumoniae
    Maria Gloria S Carvalho
    Centers for Disease Control and Prevention, Atlanta, Georgia CNPq, Rio de Janeiro, Brazil
    J Clin Microbiol 41:4415-7. 2003
    Eleven isolates representing five distinct outbreaks of pneumococcal conjunctivitis were examined for phenotypic and genetic characteristics...
  16. ncbi Ligneous conjunctivitis
    Volker Schuster
    Department of Pediatrics, Leipzig University Medical School, Leipzig, Germany
    Surv Ophthalmol 48:369-88. 2003
    Ligneous conjunctivitis (McKusick 217090) is a rare form of chronic conjunctivitis characterized by the development of firm fibrin-rich, woody-like pseudomembraneous lesions mainly on the tarsal conjunctivae...
  17. ncbi Prevalence of ocular injuries, conjunctivitis and use of eye protection among dental personnel in Riyadh, Saudi Arabia
    K A Al Wazzan
    Department of Prosthetic Dental Sciences, King Saud University, College of Dentistry, Riyadh, Saudi Arabia
    Int Dent J 51:89-94. 2001
    ..To find out the prevalence of ocular injury and infection among dental personnel in Riyadh, Saudi Arabia...
  18. ncbi Therapy with a purified plasminogen concentrate in an infant with ligneous conjunctivitis and homozygous plasminogen deficiency
    D Schott
    Department of Pediatrics, Klinikum Mannheim, University of Heidelberg, Germany
    N Engl J Med 339:1679-86. 1998
  19. ncbi Lichen planus and cicatrizing conjunctivitis: characterization of five cases
    Jennifer E Thorne
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Am J Ophthalmol 136:239-43. 2003
    To report the clinical and immunopathologic features and the response to therapy in a series of six patients with cicatrizing conjunctivitis due to lichen planus.
  20. ncbi Host range and dynamics of mycoplasmal conjunctivitis among birds in North America
    B K Hartup
    Division of Wildlife Health, College of Veterinary Medicine, Cornell University, Ithaca, New York 14853, USA
    J Wildl Dis 37:72-81. 2001
    An epidemic of conjunctivitis among house finches (Carpodacus mexicanus) caused by Mycoplasma gallisepticum (MG) bacterial infections was first described in 1994...
  21. ncbi Biofilm forming multi drug resistant Staphylococcus spp. among patients with conjunctivitis
    K Murugan
    Department of Botany and Microbiology, College of Science, King Saud University, Saudi Arabia
    Pol J Microbiol 59:233-9. 2010
    ..They were isolated from ocular patients suffering from conjunctivitis. In this study we analyzed biofilm forming ability, antibiotic resistance profile of the Staphylococcus spp...
  22. pmc Identification of an atypical zinc metalloproteinase, ZmpC, from an epidemic conjunctivitis-causing strain of Streptococcus pneumoniae
    Balaraj B Menon
    Schepens Eye Research Institute, Massachusetts Eye and Ear, Department of Ophthalmology, Harvard Medical School, 20 Staniford St, Boston, MA 02114, USA
    Microb Pathog 56:40-6. 2013
    ..In this regard, we recently reported a mechanism used by a nonencapsulated, epidemic conjunctivitis-causing strain of S. pneumoniae (strain SP168) to gain access into ocular surface epithelial cells...
  23. ncbi Streptococcus pneumoniae ocular infections, prominent role of unencapsulated isolates in conjunctivitis
    J M Marimon
    Microbiology Department, Hospital Universitario Donostia Instituto BioDonostia, San Sebastian, Spain
    Clin Microbiol Infect 19:E298-305. 2013
    ..isolates causing ocular infections in a region of northern Spain in two periods: 1999-2010 for episodes of conjunctivitis (n = 612) and 1980-2010 for uncommon and more severe non-conjunctival ocular infections (n = 36)...
  24. ncbi Clinical features, outcomes, and costs of a conjunctivitis outbreak caused by the ST448 strain of Streptococcus pneumoniae
    Michael E Zegans
    Department of Surgery, Dartmouth Hitchcock Medical Center, Lebanon, NH 03756, USA
    Cornea 28:503-9. 2009
    An outbreak of pneumococcal conjunctivitis occurred at Dartmouth College in 2002. We describe the clinical features, outcomes, and costs associated with this outbreak.
  25. ncbi Successful treatment of ligneous conjunctivitis with topical cyclosporine and heparin
    Nadia Azad
    AlShifa Trust Eye Hospital, Rawalpindi, Pakistan
    J AAPOS 13:519-20. 2009
    Ligneous conjunctivitis is a rare disease characterized by wood-like pseudomembranes developing on the ocular and extraocular mucosae...
  26. ncbi Emerging drugs for conjunctivitis
    Catherine Origlieri
    STARx Allergy and Asthma Center, UMDNJ New Jersey Medical School, 400 Mountain Avenue, Springfield, New Jersey, NJ 07081, USA
    Expert Opin Emerg Drugs 14:523-36. 2009
    b>Conjunctivitis is a highly prevalent ocular condition with potential complications that include visual impairment...
  27. ncbi Effects of Asian dust storm events on daily clinical visits for conjunctivitis in Taipei, Taiwan
    Chun Yuh Yang
    Institute of Public Health, College of Health Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Toxicol Environ Health A 69:1673-80. 2006
    ..The objective of this study was to assess the possible associations of ADS with daily clinic visits for conjunctivitis in residents in Taipei, Taiwan, during the period from 1997-2001...
  28. ncbi Erosive conjunctivitis and punctal stenosis secondary to docetaxel (taxotere)
    Craig A Skolnick
    Bascom Palmer Eye Institute, Miami, FL 33418, USA
    Eye Contact Lens 29:134-5. 2003
    To report a case of erosive conjunctivitis and punctal stenosis occurring secondarily in a patient who underwent administration of docetaxel.
  29. ncbi Brimonidine-induced anterior uveitis and conjunctivitis: clinical and histologic features
    Ethan V Nguyen
    Royal Prince Alfred Hospital, Camperdown, Sydney, New South Wales, Australia
    J Glaucoma 17:40-2. 2008
    ..We report a case of bilateral anterior uveitis and granulomatous papillary conjunctivitis in a 78-year-old gentleman after 2 years of brimonidine therapy...
  30. pmc Azithromycin reduces inflammation in a rat model of acute conjunctivitis
    Patricia Fernandez-Robredo
    Experimental Ophthalmology Laboratory, Universidad de Navarra, Pamplona Navarra, Spain
    Mol Vis 19:153-65. 2013
    ..The effect of azithromycin on inflammatory molecules in the lipopolysaccharide-induced rat conjunctivitis model was investigated.
  31. ncbi An epidemic of acute hemorrhagic conjunctivitis in the city of Sao Paulo
    K Aoki
    Aoki Eye Clinic, Sapporo, Japan
    Jpn J Ophthalmol 31:532-7. 1987
    This is a clinical and laboratory report on 98 patients with acute viral conjunctivitis who were referred to the Eye Clinic of the Escola Paulista de Medicina of Sao Paulo, Brazil, from February 1983 to February 1984...
  32. ncbi 18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis
    Leonardo Cavone
    Department of Preclinical and Clinical Pharmacology, University of Florence, Florence, Italy
    Ocul Immunol Inflamm 19:180-5. 2011
    ..Evidence indicates that extracellularly released high-mobility group box 1 protein (HMGB1) behaves as a cytokine, promoting inflammation and disease pathogenesis. HMGB1 release occurs during endophtalmitis or uveoretinitis...
  33. ncbi The international study of asthma and allergies in childhood (ISAAC): phase three rationale and methods
    P Ellwood
    Department of Paediatrics, The University of Auckland, Auckland, New Zealand
    Int J Tuberc Lung Dis 9:10-6. 2005
    ....
  34. pmc Acute conjunctivitis with episcleritis and anterior uveitis linked to adiaspiromycosis and freshwater sponges, Amazon region, Brazil, 2005
    Marcia O Mendes
    Ministry of Health, Brasilia, Brazil
    Emerg Infect Dis 15:633-9. 2009
    ..Symptomatic children responded to corticosteroid treatment. Adiaspiromycosis is a preventable cause of ocular disease in the Amazon region...
  35. ncbi Involvement of cyclooxygenase-2 in rat models of conjunctivitis
    Takayuki Oka
    Research Laboratories, Senju Pharmaceutical Co Ltd, 1 5 4 Murotani, Nishiku, Kobe 651 2241, Japan
    Curr Eye Res 29:27-34. 2004
    ..Using two animal models to determine which isoform of cyclooxygenase (COX), constitutive COX-1 or inducible COX-2, is involved in the progression of anterior ocular inflammation...
  36. ncbi Bilateral acute uveitis and conjunctivitis after zoledronic acid therapy
    J M Durnian
    Eye (Lond) 19:221-2. 2005
  37. ncbi Direct action of platelet activating factor (PAF) induces eosinophil accumulation and enhances expression of PAF receptors in conjunctivitis
    Olga Zinchuk
    Department of Ophthalmology, Laboratory of Immunology, Kochi Medical School, Nankoku, Kochi, Japan
    Mol Vis 11:114-23. 2005
    ..and PAF receptor (PAF-R) in the recruitment of eosinophils into the conjunctiva in the course of PAF induced conjunctivitis. Eosinophils are important players in the immediate hypersensitivity reactions and in allergic conjunctivitis...
  38. pmc Validation of a fornix depth measurer: a putative tool for the assessment of progressive cicatrising conjunctivitis
    Geraint P Williams
    Academic Unit of Ophthalmology, School of Immunity and Infection, University of Birmingham, UK
    Br J Ophthalmol 95:842-7. 2011
    Documentation of conjunctival forniceal foreshortening in cases of progressive cicatrising conjunctivitis (PCC) is important in ascertaining disease stage and progression...
  39. ncbi In vivo confocal microscopy of normal conjunctiva and conjunctivitis
    Elisabeth M Messmer
    Department of Ophthalmology, Ludwig Maximilians University, Munich, Germany
    Cornea 25:781-8. 2006
    ..To analyze the appearance of normal conjunctiva and conjunctival inflammation by in vivo confocal microscopy...
  40. ncbi Mucous membrane pemphigoid and pseudopemphigoid
    Jennifer E Thorne
    Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Ophthalmology 111:45-52. 2004
    ..To describe the clinical characteristics of patients with mucous membrane pemphigoid (MMP) and pseudopemphigoid...
  41. ncbi [Treatment of conjunctivitis]
    Zoltan Barabasi
    Semmelweis Egyetem, Általános Orvostudományi Kar, II Szemészeti Klinika, Budapest
    Orv Hetil 145:2107-10. 2004
  42. pmc Inflamed juvenile conjunctival naevus: clinicopathological characterisation
    Ehud Zamir
    Br J Ophthalmol 86:28-30. 2002
    ..Their clinical and histopathological features have not been characterised in series of patients. The aim of the study is to characterise IJCN clinically and histopathologically...
  43. ncbi Role of amniotic membrane transplantation for conjunctival reconstruction in ocular-cicatricial pemphigoid
    Stefano Barabino
    Department of Neurologic and Visual Sciences, University of Genoa, via Saccari 14, 18038 Sanremo, Genoa, Italy
    Ophthalmology 110:474-80. 2003
    ..To evaluate the role and the effectiveness over time of amniotic membrane transplantation (AMT) as a first-step procedure to treat conjunctival reconstruction in late-stage ocular-cicatricial pemphigoid (OCP)...
  44. ncbi Epidemic conjunctivitis in Germany, 2004
    A Schrauder
    Department for Infectious Disease Epidemiology, Robert Koch Institut, Berlin, Germany Field Epidemiology Training Programme, Berlin, Germany
    Euro Surveill 11:185-7. 2006
    Epidemic conjunctivitis can be associated with viral or bacterial pathogens, whereas epidemic keratoconjunctivitis is caused mainly by adenoviruses type 8,19 and 37...
  45. ncbi Effect of airborne allergens on emergency visits by children for conjunctivitis and rhinitis
    Sabit Cakmak
    Lancet 359:947-8. 2002
    The effect of fungal spores and pollen grains on morbidity from childhood conjunctivitis and rhinitis is mostly unknown...
  46. ncbi Immunomodulatory effect of gatifloxacin on mouse peritoneal macrophages in vitro and in models of endotoxin-induced rat conjunctivitis and rabbit bacterial keratitis
    Tomoyuki Wada
    Research Laboratories, Senju Pharmaceutical Co, Ltd, Kobe, Japan
    Ophthalmic Res 40:54-60. 2008
    ..To determine the anti-inflammatory activity of gatifloxacin in ophthalmic use...
  47. ncbi Brazil faces worst outbreak of conjunctivitis in 20 years
    Carla Finger
    Lancet 361:1714. 2003
  48. ncbi Topical corticosteroid therapy for cicatricial conjunctivitis associated with chronic graft-versus-host disease
    M R Robinson
    National Eye Institute NIH, 10 10S229, 110 Center Drive, MSC 1863, Bethesda, MD 20892 1863, USA
    Bone Marrow Transplant 33:1031-5. 2004
    ..was performed on seven patients treated with topical ocular corticosteroid therapy for progressive cicatricial conjunctivitis associated with chronic graft-versus-host disease (GVHD) following hematopoietic stem cell transplantation...
  49. ncbi Rapid response to a conjunctivitis outbreak: the use of technology to leverage information
    John H Pryor
    Dartmouth College, Hanover, New Hampshire, USA
    J Am Coll Health 50:267-71. 2002
    When an outbreak of conjunctivitis was identified at a rural New England college early in 2002, the college health center medical staff used various information management and communication systems to alert the community to the situation...
  50. ncbi Prevalence and onset of rhinitis and conjunctivitis in subjects with occupational asthma caused by trimellitic anhydride (TMA)
    Leslie C Grammer
    Division of Allergy Immunology, Ernest S Bazley Asthma and Allergic Diseases Center, Department of Medicine, Northwestern Memorial Hospital, Northwestern University Medical School, Chicago, Illinois, USA
    J Occup Environ Med 44:1179-81. 2002
    Individuals with occupational asthma may also report symptoms of rhinitis or conjunctivitis. The objective of this study was to investigate the prevalence of rhinitis and conjunctivitis in subjects with occupational asthma as a result of ..
  51. ncbi An etiological investigation of domestic cats with conjunctivitis and upper respiratory tract disease in Japan
    Yan Cai
    Department of Veterinary Microbiology, Faculty of Agriculture, Gifu University, Japan
    J Vet Med Sci 64:215-9. 2002
    ..1%), 11 (16.7%) and 14 (21.2%) cats respectively, from 66 domestic cats presented with conjunctivitis and upper respiratory tract disease (URTD) in 9 prefectures of Japan...
  52. ncbi How do GPs diagnose and manage acute infective conjunctivitis? A GP survey
    Hazel Everitt
    Community Clinical Sciences CCS Division, Faculty of Medicine, Health and Biological Sciences, Southampton University, UK
    Fam Pract 19:658-60. 2002
    To determine GPs' diagnosis and management of acute infective conjunctivitis (AIC)-one of the commonest but least researched acute infections seen in primary care.
  53. ncbi Chronic cicatrizing conjunctivitis
    H G Faraj
    Fondation Ophtalmologique A. de Rothschild and Bichat Hospital, Paris, France
    Curr Opin Ophthalmol 12:250-7. 2001
    ..Other well-known causes include thermal and chemical burns, postinfectious conjunctivitis, and Stevens-Johnson syndrome...
  54. ncbi Incidence and host determinants of work-related rhinoconjunctivitis in apprentice pastry-makers
    D Gautrin
    The Department of Chest Medicine, Hôpital du Sacré Coeur, Montreal, Canada
    Allergy 57:913-8. 2002
    ..The aim of this work was to determine the incidence of work-related rhinoconjunctivitis (RC) symptoms and their determinants...
  55. ncbi A review of plant species used to treat conjunctivitis
    Poonam Sharma
    Medicinal and Aromatic Plants Information Services, National Institute of Science Communication CSIR, Dr K S Krishnan Marg, New Delhi 110012, India
    Phytother Res 16:1-22. 2002
    b>Conjunctivitis is a major occular external infection in tropical countries. Although not a very serious disease, it gives much discomfort and sometimes leads to partial blindness or blindness due to corneal involvement...
  56. ncbi Prevalence of Chlamydophila felis and feline herpesvirus 1 in cats with conjunctivitis in northern Italy
    A Rampazzo
    College of Veterinary Medicine, University of Torino, 10095 Grugliasco, Italy
    J Vet Intern Med 17:799-807. 2003
    The prevalence of Chlamydophila felis and feline herpesvirus 1 (FHV-1) infection in cats with conjunctivitis in northern Italy was investigated by conventional polymerase chain reaction (PCR) testing...
  57. ncbi Treatment of ligneous conjunctivitis with topical plasmin and topical plasminogen
    David G Heidemann
    Department of Ophthalmology, William Beaumont Hospital, Royal Oak, Michigan, USA
    Cornea 22:760-2. 2003
    To describe treatment of a child with recalcitrant ligneous conjunctivitis secondary to a systemic plasminogen deficiency.
  58. pmc Acute unilateral conjunctivitis after rubella vaccination: the detection of the rubella genome in the inflamed conjunctiva by reverse transcriptase-polymerase-chain reaction
    N Kitaichi
    Br J Ophthalmol 90:1436-7. 2006
  59. ncbi In vivo confocal microscopy and ex vivo flow cytometry: new tools for assessing ocular inflammation applied to rabbit lipopolysaccharide-induced conjunctivitis
    Hong Liang
    Department of Ophthalmology, Centre Hospitalier National d Ophtalmologie des Quinze Vingts, Paris, France
    Mol Vis 12:1392-402. 2006
    ..We used in vivo confocal microscopy (CM) and ex vivo flow cytometry, two new tools for assessing ocular inflammation induced by LPS...
  60. pmc Estimate of the direct and indirect annual cost of bacterial conjunctivitis in the United States
    Andrew F Smith
    Medmetrics Inc, 30 Charles Street, Ottawa, Ontario, K1 M 1R2, Canada
    BMC Ophthalmol 9:13. 2009
    The aim of this study was to estimate both the direct and indirect annual costs of treating bacterial conjunctivitis (BC) in the United States. This was a cost of illness study performed from a U.S. healthcare payer perspective.
  61. ncbi Cellular characteristics of non-allergic eosinophilic conjunctivitis
    Osmo Kari
    Optokari Ltd, Espoo, Finland
    Acta Ophthalmol 88:245-50. 2010
    This study examines the histology of conjunctival biopsy samples from patients with persistent allergic eosinophilic conjunctivitis (AEC) or non-allergic eosinophilic conjunctivitis (NAEC).
  62. ncbi Study on human ophthalmomyiasis externa caused by Oestrus ovis larva, in Sirte-Libya: parasite features, clinical presentation and management
    Fouad M Fathy
    Department of Parasitology, Faculty of Medicine, Alexandria University, Egypt
    J Egypt Soc Parasitol 36:265-82, following 282. 2006
    ..Misdiagnosis is common and the condition of acute catarrhal conjunctivitis is ascribed to other causes. The study included 20 patients referred to university hospital of Sirte, Libya...
  63. ncbi Molecular and clinical spectrum of type I plasminogen deficiency: A series of 50 patients
    Katrin Tefs
    Hospital for Children and Adolescents, University of Leipzig, Oststrasse 21 25, D 04317 Leipzig, Germany
    Blood 108:3021-6. 2006
    ..The most common clinical manifestations among these patients were ligneous conjunctivitis (80%) and ligneous gingivitis (34%), followed by less common manifestations such as ligneous vaginitis (8%), ..
  64. ncbi Amniotic membrane transplantation in a case of ligneous conjunctivitis
    Stefano Barabino
    Department of Neurosciences, Ophthalmology and Genetics, University of Genoa, Genoa, Italy
    Am J Ophthalmol 137:752-3. 2004
    To report a case of ligneous conjunctivitis treated with amniotic membrane transplantation.
  65. ncbi Ligneous conjunctivitis in plasminogen-deficient mice
    A F Drew
    Divisions of Developmental Biology and Pathology, Children s Hospital Research Foundation, Cincinnati, OH 45229, USA
    Blood 91:1616-24. 1998
    Ligneous conjunctivitis is a rare form of chronic pseudomembranous conjunctivitis that is associated with systemic membranous pathological changes...
  66. ncbi Ligneous conjunctivitis: a clinicopathological, immunohistochemical, and genetic study including the treatment of two sisters with multiorgan involvement
    M Teresa Rodríguez-Ares
    Anterior Segment Unit, Department of Ophthalmology, Hospital de Conxo Complexo Hospitalario Universitario de Santiago, Galicia, Spain
    Virchows Arch 451:815-21. 2007
    Ligneous conjunctivitis (LC) is a rare disease characterized by wood-like pseudomembranes developing on the ocular and extraocular mucosae secondary to plasminogen (PLG) deficiency...
  67. ncbi Porphyria cutanea tarda presenting as cicatricial conjunctivitis
    Anna J Park
    Cornea Service, Wills Eye Hospital, Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA
    Am J Ophthalmol 134:619-21. 2002
    To report a case of porphyria cutanea tarda presenting as cicatricial conjunctivitis.
  68. ncbi Effective treatment of ligneous conjunctivitis with topical plasminogen
    Patrick Watts
    Department of Ophthalmology, The Hospital for Sick Children and Toronto Western Hospital, Toronto, Ontario, Canada
    Am J Ophthalmol 133:451-5. 2002
    The etiology of ligneous conjunctivitis is now known to be due to an underlying type 1 plasminogen deficiency. We hereby report the clinical features of three cases and their response to topically administered plasminogen.
  69. pmc New genome type of adenovirus serotype 4 caused nosocomial infections associated with epidemic conjunctivitis in Japan
    Toshihide Ariga
    Department of Ophthalmology and Visual Diseases, Hokkaido University Graduate School of Medicine, Sapporo, Japan
    J Clin Microbiol 42:3644-8. 2004
    Human adenovirus type 4 is one of the major serotypes isolated from patients with adenoviral conjunctivitis. In 2001 we encountered nosocomial infections with epidemic conjunctivitis in the ophthalmology ward of one hospital in Sapporo, ..
  70. ncbi Prevention of ligneous conjunctivitis by topical and subconjunctival fresh frozen plasma
    Khalid F Tabbara
    The Eye Center and The Eye Foundation for Research in Ophthalmology, Riyadh, Saudi Arabia
    Am J Ophthalmol 138:299-300. 2004
    To present a case of ligneous conjunctivitis where the recurrence of membranous conjunctivitis was prevented by subconjunctival and topical instillation of fresh frozen plasma.
  71. ncbi Dynamics of PAF-induced conjunctivitis reveals differential expression of PAF receptor by macrophages and eosinophils in the rat
    Olga Zinchuk
    Laboratory of Immunology, Department of Ophthalmology, Kochi Medical School, Nankoku, Kochi, 783 8505, Japan
    Cell Tissue Res 317:265-77. 2004
    ..microscopy to examine the dynamic changes of PAF-R expression in the conjunctiva in response to PAF-induced conjunctivitis in Brown Norway rats within the first 2 h after topical administration of PAF...
  72. ncbi [Red eye in children]
    Arnaud Sauer
    Service d Ophtalmologie, CHU de Strasbourg, Universite Louis Pasteur, 67084 Strasbourg Cedex
    Rev Prat 58:353-7. 2008
    ..Unfortunately, physical examination on children is not always easy. Consultation with an ophthalmologist is justified if a doubt remains, in case of chronic pathology or resistance to first intention treatment...
  73. ncbi Inflammatory and mechanical complications associated with 3 years of up to 30 nights of continuous wear of lotrafilcon A silicone hydrogel lenses
    Peter Donshik
    University of Connecticut Health Center, Farmington, CT, USA
    Eye Contact Lens 33:191-5. 2007
    ..To report the ocular complications occurring during a 3-year clinical trial of subjects wearing lotrafilcon A silicone hydrogel lenses for up to 30 nights of continuous wear...
  74. ncbi Cutaneous and ocular signs of childhood rosacea
    Melanie Chamaillard
    Unité de dermatologie pédiatrique, Place Amelie Raba Leon, 33 076 Bordeaux Cedex, France
    Arch Dermatol 144:167-71. 2008
    ..Objectives To describe the clinical features of cutaneous and ocular manifestations of childhood rosacea, to propose diagnostic criteria, and to emphasize the possible severity of ocular complications in this age group...
  75. ncbi The red eye
    F Hampton Roy
    University of Arkansas Medical Science Campus, Little Rock, AR, USA
    Ann Ophthalmol (Skokie) 38:35-8. 2006
    ..Ciliary injection indicates inflammation of the cornea, iris, or ciliary body, whereas conjunctival injection mainly affects the posterior conjunctival blood vessels...
  76. ncbi Clinical analysis of patients with pemphigoid-like ophthalmological symptoms
    Joanna Moneta-Wielgos
    Department of Ophthalmology, Medical University of Warsaw, Poland
    Neuro Endocrinol Lett 27:741-4. 2006
    ..The aim of this study was a clinical analysis of patients with symptoms typical of pemphigoid...
  77. ncbi Role of electron microscopy in the diagnosis of ocular mucous membrane pemphigoid
    Jennifer E Thorne
    Department of Ophthalmology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Ophthalmology 113:1651-6. 2006
    To evaluate the role of electron microscopy (EM) for the diagnosis of ocular mucous membrane pemphigoid (MMP) among patients with cicatrizing conjunctivitis.
  78. ncbi [Pepper spray injuries of the anterior segment of the eye]
    C Kniestedt
    Augenklinik Kantonspital Winterthur, Winterthur, Schweiz
    Klin Monbl Augenheilkd 222:267-70. 2005
    ..A wide variety of pepper sprays is currently available and gaining increasing popularity among both professional guardians and amateurs. Adverse side effects to the anterior segment of the eye are known but underestimated...
  79. ncbi [Ocular penfigoid scar]
    Alejandro Malbran
    Medicina (B Aires) 66:154. 2006
  80. pmc Trefoil factor family 1, MUC5AC and human leucocyte antigen-DR expression by conjunctival cells in patients with glaucoma treated with chronic drugs: could these markers predict the success of glaucoma surgery?
    M Souchier
    Service d Ophtalmologie, Hopital General, 21000 Dijon, France
    Br J Ophthalmol 90:1366-9. 2006
    ....
  81. pmc Topical ciclosporin in the treatment of ocular surface disorders
    S Tatlipinar
    The Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD 21287 9238, USA
    Br J Ophthalmol 89:1363-7. 2005
    ....
  82. ncbi Allergic reaction to topical eyedrops
    Christophe Baudouin
    Department of Ophthalmology, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Curr Opin Allergy Clin Immunol 5:459-63. 2005
    ..As allergy is only one possible mechanism, this review was extended to all reports or studies describing allergic, inflammatory or toxic effects related to eyedrops since 2004...
  83. ncbi Group IIA phospholipase A(2) concentration of tears in patients with ocular rosacea
    Osmo Kari
    Department of Allergology, University of Helsinki, Helsinki, Finland
    Acta Ophthalmol Scand 83:483-6. 2005
    ..To determine the concentration of group IIA phospholipase A(2) (GIIAPLA(2)) in tears of patients with ocular rosacea, and to compare it with GIIAPLA(2) concentration in tears of age-matched healthy controls...
  84. ncbi Role of macrophage migration inhibitory factor in conjunctival pathology in ocular cicatricial pemphigoid
    Mohammed S Razzaque
    Department of Oral Medicine, Harvard School of Dental Medicine, Boston, Massachusetts 02115, USA
    Invest Ophthalmol Vis Sci 45:1174-81. 2004
    ..Ocular cicatricial pemphigoid (OCP) is an autoimmune disease in which affected conjunctivae show features of an immunoinflammatory disease. In this study, the role of MIF in the pathogenesis of OCP was examined...
  85. pmc Conjunctival markers as predictable markers for preoperative glaucoma assessment
    P J Pisella
    Br J Ophthalmol 90:1335-6. 2006
  86. ncbi Inadvertent conjunctival trauma related to contact with drug container tips: a masquerade syndrome
    Abraham Solomon
    Department of Ophthalmology, Hadassah University Hospital, Jerusalem, Israel
    Ophthalmology 110:796-800. 2003
    ..To report the diagnosis, clinical course, and management of acute painful red eye syndrome associated with unintentional tube- or bottle-tip-induced conjunctival trauma...
  87. ncbi Role of connective tissue growth factor in the pathogenesis of conjunctival scarring in ocular cicatricial pemphigoid
    Mohammed S Razzaque
    Department of Oral Medicine, Infection and Immunity, Harvard School of Dental Medicine, Boston, Massachusetts 02115, USA
    Invest Ophthalmol Vis Sci 44:1998-2003. 2003
    ..Hence, studying the mechanism by which CTGF influences TGF-beta1-induced synthesis of collagen in conjunctiva of patients with OCP would provide insight into the mechanism of conjunctival fibrosis in patients with OCP...
  88. ncbi [Ligneous conjunctivitis in a patient with plasminogen type I deficiency--case report with review of literature]
    Carsten Heinz
    Universitätsaugenklinik Essen, Germany
    Klin Monbl Augenheilkd 219:156-8. 2002
    Ligneous conjunctivitis is a rare chronic pseudomembranous conjunctivitis. It forms nodular masses on the palpebral conjunctiva. Beside the conjunctival affection pseudomembranes can also be found on other mucosal tissues.
  89. ncbi Chronic cicatrizing conjunctivitis in a patient with ocular cicatricial pemphigoid and fatal Wegener granulomatosis
    E Miserocchi
    Immunology and Uveitis Service, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, 243 Charles St, Boston, MA 02114, USA
    Am J Ophthalmol 132:923-4. 2001
    PURPOSE: To describe a case of chronic cicatrizing conjunctivitis in a patient with ocular cicatricial pemphigoid and Wegener granulomatosis. METHODS: Observational case report. A retrospective study...
  90. ncbi Role of collagen-binding heat shock protein 47 and transforming growth factor-beta1 in conjunctival scarring in ocular cicatricial pemphigoid
    Mohammed S Razzaque
    Department of Dermatology, Harvard Medical School, Boston, Massachusetts, USA
    Invest Ophthalmol Vis Sci 44:1616-21. 2003
    ..Heat shock protein 47 (HSP47), a collagen-binding protein, plays an important role in the biosynthesis of procollagens. In the present study, we examined the role of HSP47 in conjunctival scarring in patients with OCP...
  91. ncbi Amniotic membrane transplantation elicits goblet cell repopulation after conjunctival reconstruction in a case of severe ocular cicatricial pemphigoid
    Stefano Barabino
    Department of Neurological and Visual Sciences Ophthalmology R, University of Genoa, Genoa, Italy
    Acta Ophthalmol Scand 81:68-71. 2003
    ..This study reports the postoperative clinical and cytological outcomes of a human amniotic membrane transplantation (AMT) to rebuild the conjunctiva in a case of late stage OCP...
  92. ncbi Ocular surface changes induced by topical antiglaucoma monotherapy
    Barbara Cvenkel
    Eye Clinic, Medical Center Ljubljana, Medical Faculty, Slovenia
    Ophthalmologica 216:175-9. 2002
    ..To investigate the expression of inflammatory markers HLA-DR in impression cytology specimens from patients receiving topical antiglaucoma monotherapy...
  93. ncbi Tarsal-conjunctival disease associated with Wegener's granulomatosis
    Michael R Robinson
    National Eye Institute, National Institutes of Health, Bethesda, Maryland, USA
    Ophthalmology 110:1770-80. 2003
    ..To describe the clinical characteristics of tarsal-conjunctival disease in a cohort of patients with Wegener's granulomatosis (WG)...
  94. ncbi [Effect of preservatives on the conjunctiva: a comparative study of beta-blocker eye drops with and without preservatives in glaucoma patients]
    P J Pisella
    Service d Ophtalmologie, CHU de Tours, Hopital Bretonneau, 2, boulevard Tonnelle, 37044 Tours Cedex 1
    J Fr Ophtalmol 26:675-9. 2003
    ..To compare the effect of timolol with or without preservatives on the conjunctival epithelium of glaucoma patients...
  95. ncbi The role of conjunctival biopsy in the diagnosis of Wegener's granulomatosis: a case report
    Petros C Karakousis
    Department of Internal Medicine, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    Can J Ophthalmol 37:179-81. 2002
  96. ncbi Diagnostic and therapeutic challenges
    H Richard McDonald
    Retina 23:852-4. 2003
  97. ncbi Clinical application of living-related conjunctival-limbal allograft
    Kazuo Tsubota
    Department of Ophthalmology, Tokyo Dental College, Ichikawa shi, Chiba, Japan
    Am J Ophthalmol 133:134-5. 2002
    ..To report one successful case of conjunctival-limbal allograft for the treatment of a severe ocular surface disorder...
  98. ncbi The cell-layer- and cell-type-specific distribution of GalNAc-transferases in the ocular surface epithelia is altered during keratinization
    PABLO ARGUESO
    Department of Ophthalmology, Schepens Eye Research Institute, Harvard Medical School, 20 Staniford Street, Boston, MA 02114, USA
    Invest Ophthalmol Vis Sci 44:86-92. 2003
    ..The purpose of this study was to determine the cellular distribution of GalNAc-Ts in the normal ocular surface epithelia and to compare their distribution with that in pathologically keratinized conjunctival epithelia...
  99. ncbi Efficacy of indomethacin 0.1% and fluorometholone 0.1% on conjunctival inflammation following chronic application of antiglaucomatous drugs
    Christophe Baudouin
    Hôpital A Paré, Boulogne Billancourt, France
    Graefes Arch Clin Exp Ophthalmol 240:929-35. 2002
    ..1%) on conjunctival inflammation following chronic application of antiglaucomatous drugs, in comparison with a steroidal ophthalmic solution (preserved fluorometholone)...
  100. ncbi Ag-specific recognition, activation, and effector function of T cells in the conjunctiva with experimental immune-mediated blepharoconjunctivitis
    Atsuki Fukushima
    Department of Ophthalmology, Kochi Medical School, Nankoku City, Japan
    Invest Ophthalmol Vis Sci 44:4366-74. 2003
    To investigate antigen (Ag) specificity, activation, and effector function of the Ag-specific T cells involved in the development of experimental immune-mediated blepharoconjunctivitis (EC), an experimental conjunctivitis.
  101. ncbi Cicatrizing and autoimmune diseases
    Saadia Rashid
    Schepens Eye Research Institute, Harvard Medical School, Boston, MA 02114, USA
    Chem Immunol Allergy 92:195-202. 2007
    ..These conditions, though generally infrequent, can be the cause of profound pathology and visual disability, and often need systemic immune modulation for therapy...

Research Grants62

  1. Enterovirus RNA Translation and Replication
    David J Barton; Fiscal Year: 2013
    ..human diseases including acute flaccid paralysis (paralytic poliomyelitis), aseptic meningitis, myocarditis, conjunctivitis and fatal systemic infections of neonates...
  2. A Rapid Point-of-care Diagnostic for C. trachomatis STDs
    Richard F Selden; Fiscal Year: 2013
    ..If an infected pregnant woman is not treated, her baby has a 50% chance of developing conjunctivitis and a 20% chance of pneumonia in the first six months of life...
  3. Role of HSV Induced RNA Degradation in Pathogenesis
    David A Leib; Fiscal Year: 2013
    ..HSV causes a variety of ocular diseases ranging from self-limiting dendritic epithelial keratitis, conjunctivitis, and blepharitis, to severe necrotizing stromal keratitis...
  4. Bacteria-Mucin Interactions at the Ocular Surface
    Ilene K Gipson; Fiscal Year: 2012
    ..Other types of infection, e.g., outbreaks of bacterial conjunctivitis from non-encapsulated Streptococcus pneumoniae (SPN), occur without evidence of ocular surface damage...
  5. Encapsidation of Adenovirus DNA
    Michael J Imperiale; Fiscal Year: 2010
    ..associated with a variety of diseases including upper respiratory infections, gastrointestinal illness, and conjunctivitis. Adenovirus infections are a significant clinical problem in transplant recipients, particularly pediatric ..
  6. Conjunctival Goblet Cell NLRP3 Inflammasome in Ocular Surface Bacterial Infection
    Darlene A Dartt; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Bacterial conjunctivitis and keratitis occur in approximately 25,000 Americans annually with Staphylococcus aureus (S. aureus) being the leading cause of infection...
  7. Diversity and Dynamic Stability of the Ocular Surface Microbiome
    Russell N Van Gelder; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Ocular infectious diseases, including microbial keratitis, conjunctivitis, and endophthalmitis, remain a significant cause of potentially blinding disease...
  8. Lipid Rafts in Adenoviral Ocular Pathogenesis
    Jaya Rajaiya; Fiscal Year: 2013
    ..The clinical manifestations of this infection include severe pseudomembranous conjunctivitis and epithelial keratitis, followed by multifocal subepithelial (stromal) corneal infiltrates that cause ..
  9. THE IMMUNOBIOLOGY OF CORNEAL ALLOGRAFTS
    Jerry Niederkorn; Fiscal Year: 2013
    ..The first specific aim explores the immune mechanisms whereby allergic diseases such as asthma and allergic conjunctivitis abolish corneal immune privilege and profoundly increase the incidence and tempo of corneal allograft ..
  10. Evaluation of CPAF Mediated Anti-Chlamydial Immunity in the Guinea Pig
    BERNARD PRAGASH ARULANANDAM; Fiscal Year: 2012
    ..caviae, the causative agent of guinea pig inclusion conjunctivitis (GPIC)...
  11. Enterovirus RNA Translation and Replication
    David Barton; Fiscal Year: 2009
    ..human diseases including acute flaccid paralysis (paralytic poliomyelitis), aseptic meningitis, myocarditis, conjunctivitis and fatal systemic infections of neonates...
  12. Conjunctival Goblet Cell Mucin Secretion in Inflammation and Its Resolution
    Darlene A Dartt; Fiscal Year: 2012
    ..diseases of ocular surface inflammation and allergic inflammation such as dry eye and most forms of allergic conjunctivitis. Goblet cell mucins protect the ocular surface from the external environment and loss of filled goblet cells ..
  13. Roles of CC chemokine activity in mast cell responses and ocular allergy
    Santa Jeremy Ono; Fiscal Year: 2012
    ..aims: 1) to examine the mast cell-priming role of eotaxin-1-CCR3 activity in a murine model of allergic conjunctivitis; 2) to explore the costimulatory role of MIP-1[unreadable]-CCR1 signaling in mast cell activation in vivo;3) ..
  14. Cellular and Molecular Mechanisms that Contribute to Ocular Surface Allergy
    DANIEL RAPHAEL SABAN; Fiscal Year: 2013
    PROJECT SUMMARY Allergic conjunctivitis (AC) affects nearly 30 million Americans, thereby constituting a major health problem and causing significant health care costs in the United States...
  15. Immunopathogenesis of Adenovirus Keratitis
    James Chodosh; Fiscal Year: 2013
    ..The clinical manifestations of this infection include severe membranous conjunctivitis and epithelial keratitis, followed by multifocal subepithelial (stromal) corneal infiltrates that cause ..
  16. Rapid tests for Chlamydia and Neglected Tropical Diseases
    Abhay N Vats; Fiscal Year: 2013
    Trachoma, a chronic conjunctivitis caused by repeated infections with C. trachomatis, is a leading cause of blindness for poverty-stricken communities in Africa, Asia, and the Middle East...
  17. ROLE OF CELL INTEGRINS IN ADENOVIRAL CONJUNCTIVITIS
    Glen R Nemerow; Fiscal Year: 2012
    ..abstract_text> ..
  18. Control of airway inflammation and Th2 differentiation by microRNA 21
    Alexander L Dent; Fiscal Year: 2012
    ..worldwide, with almost 50% of the urban population presenting with atopic diseases including asthma, rhino- conjunctivitis, sinusitis, food allergy, and atopic dermatitis...
  19. Chlamydia co-option of Eukaryotic Lipid Droplets
    Raphael H Valdivia; Fiscal Year: 2010
    ..are obligate intracellular pathogens that cause a range of acute and chronic diseases including trachoma, conjunctivitis, pelvic inflammatory disease and atypical pneumonias...
  20. In Vivo Imaging of Leukocyte-Endothelial Dynamics
    William Mathers; Fiscal Year: 2005
    ..compare leukocyte-endothelial dynamics in specific vascular beds in seven disease states: a) allergic seasonal conjunctivitis, b) Sjogren's syndrome and dry eye, c) blepharitis, d) graft versus host disease (GVHD), e) episcleritis, f) ..
  21. Study of monkeypox virus in rodents
    R Buller; Fiscal Year: 2005
    ..S. showed none of the expected signs of a lethal infection with monkeypox virus (e.g. conjunctivitis, lymphadenopathy and skin lesions) yet were able to efficiently transmit the disease to prairie dogs that were ..
  22. Y ENTEROCOLITICA VIRULENCE PLASMID
    John Morris; Fiscal Year: 1991
    ..We have also identified a 2.8kb BamHI fragment that encodes factors responsible for conjunctivitis in guinea pigs (the Sereny reaction)...
  23. OCCUPATIONAL ASTHMA ASOCIATED WITH SEAFOOD PROCESSING
    Thomas Robins; Fiscal Year: 2001
    ..A second aim is to determine the prevalence of allergic sensitization and health outcomes (rhino-conjunctivitis, urticaria/dermatitis and asthma) due to processing of rock lobster and saltwater bony fish through subject ..
  24. Primate enteroviruses transmission in Bangladesh
    Lisa Jones Engel; Fiscal Year: 2007
    ..can cause a wide variety of human illnesses including neurologic disease, myocarditis, acute hemorrhagic conjunctivitis and neonatal sepsis-like disease...
  25. Import of Adenovirus DNA into the nucleus
    Larry Gerace; Fiscal Year: 2007
    ..They also are a major cause of viral conjunctivitis including epidemic keratoconjunctivitis (EKC), a condition that can threaten long-term visual function and for ..
  26. Carboxylated polysaccharides for drug delivery to the eye
    Wendy Townsend; Fiscal Year: 2006
    ..These diseases range from bacterial conjunctivitis to intraocular inflammation. Keratoconjunctivitis sicca (dry eye) affects nearly 30 million people...
  27. GENETICS OF H. AEGYPTIUS BRAZILIAN PURPURIC FEVER CLONE
    Luis Actis; Fiscal Year: 2000
    ..aegyptius), a bacterial species that is normally non-invasive and causes mild cases of conjunctivitis. The unusual invasive attributes of the BPF clone of H...
  28. PATHOGENESIS AND EARLY DIAGNOSIS OF EYE INFLAMMATIONS
    Chandler Dawson; Fiscal Year: 1980
    ..Chlamydial Studies: The growth curves of guinea pig inclusion conjunctivitis (GPIC) in organ culture of guinea pig (g.p.) conjunctiva will be determined...
  29. Genetics of Ocular Adenoviruses
    James Chodosh; Fiscal Year: 2006
    ..EKC in highly contagious, manifests acutely with severe conjunctivitis and epithelial keratitis, and is associated with the delayed development of stromal (subepithelial) keratitis...
  30. Enterovirus RNA Translation and Replication
    David Barton; Fiscal Year: 2003
    Enteroviruses cause a diverse spectrum of human diseases including conjunctivitis, myocarditits, aseptic meningitis, acute flaccid paralysis, and fatal systemic infections in neonates...
  31. DNA-BASED AMPLIFICATION ASSAY FOR CHLAMYDIA TRACHOMATIS
    HWATANG WANG; Fiscal Year: 1993
    ..pathogen responsible for a wide range of infections including lymphogranuloma venereum, trachoma, inclusion conjunctivitis and genital tract infections...
  32. Functional Genomic Analysis of the Chlamydia Inclusion
    RAPHAEL VALDIVIA; Fiscal Year: 2005
    ..is a widely disseminated, obligate intracellular pathogen that causes a range of diseases including trachoma, conjunctivitis and pelvic inflammatory disease. Within infected cells, C...
  33. Alteration of host iron homeostasis by Neisseria
    ROBERT BONNAH; Fiscal Year: 2005
    ..gonorrhoeae (GC) infects a variety of mucosal epithelial surfaces, including the eye, causing hyperacute conjunctivitis. Untreated, these infections can cause visual impairment and blindness...
  34. PATHOGENESIS OF CONJUNCTIVITIS IN THE EYE
    SANTA ONO; Fiscal Year: 2000
    DESCRIPTION: Conjunctivitis is the major atopic disease affecting the ocular surface. Indeed, it is one of the most commonly observed diseases in ophthalmic clinics...
  35. BIOLOGY OF C CLUSTER COXSACKIEVIRUSES
    Eckard Wimmer; Fiscal Year: 2000
    ..in particular the Coxsackie A24 virus (CAV24), and the CAV24v that is a variant the causes hemorrhagic conjunctivitis. The sequences will also be used in studies of the evolutionary relationships between the various C-CAVs...
  36. BIOLOGY OF PHAGE INFECTION IN CHLAMYDIA
    Patrik Bavoil; Fiscal Year: 2005
    ..We have isolated a bacteriophage, phiCPG1 from the model Chlamydia psittaci strain ?Guinea Pig Inclusion Conjunctivitis?...
  37. Drug loaded punctum plug for treatment of ocular disease
    TAMARA WIDENHOUSE; Fiscal Year: 2002
    ..graft/transplants, glaucoma, temporary increase in IOP following cataract or other ocular surgery, bacterial conjunctivitis, and corneal ulcers...
  38. ANTIGEN PRESENTATION--MODEL OF ALLERGIC EYE DISEASE
    Gilles Benichou; Fiscal Year: 2003
    ..We have recently developed a mouse model of allergic conjunctivitis to cat dander (Fel dl), and characterized the T helper responses in susceptible animals...
  39. FUNCTION AND ROLE OF HSV-1 ICP34.5 IN ENCEPHALITIS
    KENNETH ROSENTHAL; Fiscal Year: 2000
    ..simplex virus type 1 (HSV-1) is a common oral and genital pathogen that is also a leading cause of kerato-conjunctivitis leading to blindness and encephalitis...
  40. Neonatal immunity against C. trachomatis infections
    Sukumar Pal; Fiscal Year: 2009
    ..trachomatis transmit infections to their neonates at birth. Neonatal chlamydial infections include inclusion conjunctivitis and pneumonia. In the U.S., the rate of neonatal infection is 8.2 per 1,000 live births...
  41. Interactions between ocular tissue and RSV
    Sailen Barik; Fiscal Year: 2004
    ..times, studies from our laboratory and others' have established a significant association between allergic conjunctivitis and the presence of RSV and cytokines in the eye...
  42. Novel ophthalmic drug delivery vehicles
    HANS HOFLAND; Fiscal Year: 2002
    ..delivery platform could be used commercially in patients to reduce inflammation due to seasonal or bacterial conjunctivitis, to reduce post-surgical pain and inflammation, to prevent or treat fungal or bacterial infections of the eye, ..
  43. Safety and Efficacy of C31G for Ocular Infections
    Richard Bax; Fiscal Year: 2003
    Bacterial and viral conjunctivitis are extremely common conditions and can result in a wide range of pathologies...
  44. HOME HYGIENE INTERVENTION
    Elaine Larson; Fiscal Year: 2002
    ..persons in the same household with at least one related symptom (vomiting, diarrhea, fever, runny nose, cough, conjunctivitis, skin infection)...
  45. GENETIC AND MOLECULAR BASIS OF FAMILIAL COLD URTICARIA
    Harold Hoffman; Fiscal Year: 2002
    ..The achievement of these goals will result in identification of the gene responsible for familial cold urticaria which will ultimately lead to an understanding of the mechanism of the inflammatory response to a physical stimulus. ..
  46. Novel regulatory role of cryopyrin in inflammation
    Harold Hoffman; Fiscal Year: 2005
    ..abstract_text> ..
  47. Visual outcomes & quality of life in CMV retinitis
    Jennifer Thorne; Fiscal Year: 2006
    ..abstract_text> ..
  48. Host response to Chlamydia genital infection in the male
    Roger Rank; Fiscal Year: 2008
    ..has been studied is the guinea pig infected with the Chlamydia psittaci agent of guinea pig inclusion conjunctivitis (GPIC), a natural parasite of the guinea pig...
  49. Latino Eye Health: A Communication Strategy for Diabetes
    Sheila West; Fiscal Year: 2007
    ..Improvements in eye care seeking behaviors should help in avoiding visual loss from diabetic retinopathy and macula edema, the leading causes of visual loss in the working age Latino population. [unreadable] [unreadable]..
  50. Transmissibility of Influenza A Viruses
    Daniel Perez; Fiscal Year: 2006
    ..The techniques needed to obtain this information are now available, and the results will lay the groundwork for important changes in agricultural policies and pandemic planning. ..
  51. Mast Cell-Induced Inflammation in Vascular Disease
    Kottarappat N Dileepan; Fiscal Year: 2010
    ..abstract_text> ..
  52. Direct IL-4 and IL-13 effects on pulmonary smooth muscle in allergic airway disea
    FRED DOUGLASS FINKELMAN; Fiscal Year: 2010
    ..Proposed studies with a mouse model in which airway hyperresponsiveness is induced solely by direct IL-4 and IL-13 effects on smooth muscle should help to elucidate these mechanisms and may reveal new approaches for asthma therapy. ..
  53. Role of Inflammatory Cytokines in the Allergic Response
    Fred Finkelman; Fiscal Year: 2007
    ..abstract_text> ..
  54. IL4R AND IMMUNITY TO GI NEMATODE PARASITES
    Fred Finkelman; Fiscal Year: 2003
    ....
  55. Control of Conjuctival Goblet Cell Mucin Production
    Darlene Dartt; Fiscal Year: 2009
    ..Study of the signaling pathways that stimulate conjunctival goblet cell proliferation will lead to the development of treatments to replenish the mucin layer in these diseases. ..
  56. AMD AND RISK FACTORS IN A HISPANIC POPULATION
    Sheila West; Fiscal Year: 2003
    ..Such data will advance our understanding of the magnitude of AMD in this ethnic group, and the way in which risk factors relate to AMD in different populations. ..
  57. Annotation of the Mycoplasma alligatoris genome
    Daniel Brown; Fiscal Year: 2002
    ..The ease of PCR-based cloning and the accessibility of bioinformatics software make this an ideal project to engage undergraduate students in innovative biomedical research. ..
  58. ENDOTHELIUM--SIGNALING FROM MAST CELLS TO EOSINOPHILS
    David Broide; Fiscal Year: 2002
    ....