Genomes and Genes
endocrine system diseases
Summary: Pathological processes of the ENDOCRINE GLANDS, and diseases resulting from abnormal level of available HORMONES.
Publications234 found, 100 shown here
- Surgeon volume as a predictor of outcomes in inpatient and outpatient endocrine surgeryAlexandra I Stavrakis
Endocrine Surgical Unit and Center for Surgical Outcomes and Quality, VA Greater Los Angeles Healthcare System, Los Angeles, Calif, USA
Surgery 142:887-99; discussion 887-99. 2007..We examined the effect of surgeon volume on clinical and economic outcomes for thyroid, parathyroid, and adrenal surgery across inpatient and outpatient settings...
- Intellectual and functional outcome of children 3 years old or younger who have CNS malignanciesMaryam Fouladi
Department of Hematology Oncology, St Jude Children s Research Hospital, 332 N Lauderdale, Memphis, TN 38105 2794, USA
J Clin Oncol 23:7152-60. 2005....
- Secondary diabetes associated with principal endocrinopathies: the impact of new treatment modalitiesEugenia Resmini
Department of Endocrinology and Medical Sciences, Center of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, 6, 16132, Genoa, Italy
Acta Diabetol 46:85-95. 2009..Indeed, it has been demonstrated that insulin glargine, given once daily, reduces the risk of hypoglycaemia compared with other formulations, and can facilitate a more aggressive insulin treatment in this class of patients...
- Investigation of new co-factors in 49 patients with pyoderma gangrenosumPhilipp Al Ghazal
Clinic and Polyclinic for Dermatology, Venereology, and Allergology, Essen University Hospital, Hufelandstrasse 55, Essen, Germany
J Dtsch Dermatol Ges 10:251-7. 2012..According to current textbooks, it is often associated with chronic inflammatory bowel diseases or other autoimmune disorders...
- Prevalence of symptomatic androgen deficiency in menAndre B Araujo
New England Research Institutes, 9 Galen Street, Watertown, Massachusetts 02472, USA
J Clin Endocrinol Metab 92:4241-7. 2007..Despite recognition that androgen deficiency in men should be defined according to biochemical and clinical criteria, most prevalence estimates are based on low testosterone levels alone...
- Who performs endocrine operations in the United States?Brian D Saunders
Department of Surgery, Divisions of Endocrine Surgery and Vascular Surgery, University of Michigan, 1500 E Medical Center Drive, Taubman Center 2920H, Ann Arbor, MI 48109 0331, USA
Surgery 134:924-31; discussion 931. 2003..Endocrine surgery is a discipline that is dedicated to high-quality care of patients with endocrine surgical disease. The relationship between its "identity" as a separate field and clinical practice patterns is not known...
- McCune-Albright syndromeClaudia E Dumitrescu
Skeletal Clinical Studies Unit, Craniofacial and Skeletal Diseases Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland, USA
Orphanet J Rare Dis 3:12. 2008..Treatment of all endocrinopathies is required. Malignancies associated with MAS are distinctly rare occurrences. Malignant transformation of FD lesions occurs in probably less than 1% of the cases of MAS...
- Glucocorticoid resistance syndrome: A diagnostic and therapeutic approachElisabeth F C van Rossum
University Medical Center, Department of Internal Medicine Room D400, Erasmus Medical Center, Dr Molewaterplein 40, 3015 GD Rotterdam, The Netherlands
Best Pract Res Clin Endocrinol Metab 20:611-26. 2006..Diagnosis of generalized GC resistance can be difficult. This review highlights the diagnostic process and therapeutic options for treating patients with this disease...
- Endocrine disorders in two sisters affected by MELAS syndromeP Balestri
Department of Pediatrics, University of Siena, Italy
J Child Neurol 15:755-8. 2000....
- Radical resection of craniopharyngiomaGraciela Zuccaro
Department of Neurosurgery, Hospital Nacional de Pediatria Juan P Garrahan, Buenos Aires, Argentina
Childs Nerv Syst 21:679-90. 2005..Trying to remove a craniopharyngioma that has been treated previously with other methods is, in our experience, much more dangerous because of adherences of the tumor to vascular and neural structures...
- The maturation of a specialty: Workforce projections for endocrine surgeryJulie Ann Sosa
Section of Endocrine Surgery, Department of Surgery, Yale New Haven Hospital, Yale University School of Medicine, New Haven, Conn, USA
Surgery 142:876-83. 2007..Fellowship programs will lead to more specialty-trained endocrine surgeons. We make projections for the supply of endocrine surgeons and demand for endocrine procedures over the next 15 years...
- Long-term neurological, visual, and endocrine outcomes following transnasal resection of craniopharyngiomaIndro Chakrabarti
Department of Neurological Surgery, University of Southern California, Los Angeles, California 90032, USA
J Neurosurg 102:650-7. 2005..More specifically, they evaluate the role of the TN approach in the management of craniopharyngioma...
- Long-term results of the surgical treatment of craniopharyngioma: the experience at the Policlinico Gemelli, Catholic University, RomeM Caldarelli
Section of Pediatric Neurosurgery, Institute of Neurosurgery, Catholic University Medical School, Rome, Italy
Childs Nerv Syst 21:747-57. 2005..In order to avoid such complications, some authors have suggested to renounce to radical resection and to rely on post-operative radiation therapy to minimise the risk of residual tumour progression...
- Craniopharyngioma in children: Marseille experienceGabriel Lena
Department of Pediatric Neurosurgery, hôpital des Enfants La Timone, 264, rue Saint Pierre, 13385, Marseille, Cedex 05, France
Childs Nerv Syst 21:778-84. 2005....
- Endocrine complications of hematopoietic stem cell transplantationWassim Chemaitilly
Department of Pediatrics, Schneider Children s Hospital, 269 01 76th Avenue, New Hyde Park, NY 11040, USA
Endocrinol Metab Clin North Am 36:983-98; ix. 2007..This article focuses on the late endocrine abnormalities that are most commonly observed following successful HSCT, with a special emphasis on pediatric HSCT recipients, for whom long-term follow-up data are increasingly available...
- Secondary causes of osteoporosisLorraine A Fitzpatrick
Division of Endocrinology, Diabetes, Metabolism, Nutrition, and Internal Medicine, Rochester, MN 55905, USA
Mayo Clin Proc 77:453-68. 2002..This article provides the framework for understanding causes of bone loss and approaches to their management...
- Steroidogenic factor-1 (SF-1) and its relevance to pediatric endocrinologyBruno Ferraz de-Souza
UCL Institute of Child Health and Department of Medicine, University College London, UK
Pediatr Endocrinol Rev 3:359-64. 2006....
- Reproductive function and risk for PCOS in women treated for bipolar disorderNatalie L Rasgon
Department of Psychiatry, Stanford School of Medicine, Palo Alto, CA, USA
Bipolar Disord 7:246-59. 2005..This study examined the reproductive function and prevalence of polycystic ovary syndrome (PCOS) in women with bipolar disorder taking antimanic medications...
- A multiplex human syndrome implicates a key role for intestinal cell kinase in development of central nervous, skeletal, and endocrine systemsPiya Lahiry
Robarts Research Institute, London, Ontario N6A 5K8, Canada
Am J Hum Genet 84:134-47. 2009..We also demonstrate that the R272Q mutant fails to localize at the nucleus and has diminished kinase activity. These findings suggest that ICK plays a key role in the development of multiple organ systems...
- Image diagnosis in McCune-Albright syndromeClaudio Defilippi
Radiology Department, Regina Margherita Children s Hospital, Turin, Italy
J Pediatr Endocrinol Metab 19:561-70. 2006..Bone scintigraphy with technetium 99 is essential in the follow-up of the disease. Ultrasonography is very useful in ovarian cyst follow-up and in the detection of thyroid and adrenal nodules and testicular microlithiasis...
- Minireview: PRKAR1A: normal and abnormal functionsIoannis Bossis
Section on Endocrinology and Genetics, Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892 1862, USA
Endocrinology 145:5452-8. 2004....
- McCune-Albright syndrome and disorders due to activating mutations of GNAS1Alejandro Diaz
Division of Pediatric Endocrinology, Weill Medical College of Cornell University, New York, NY, USA
J Pediatr Endocrinol Metab 20:853-80. 2007..We discuss here the clinical consequences of GNAS1 activating mutations in different body systems and organs, the diagnostic approach to MAS, and the current therapeutic recommendations...
- Endocrine dysfunction and parameters of the metabolic syndrome after bone marrow transplantation during childhood and adolescenceS Shalitin
Institute for Endocrinology and Diabetes, Schneider Children s Medical Center of Israel, 14 Kaplan Street, Petach Tikva 49202, Israel
Bone Marrow Transplant 37:1109-17. 2006..9% of the 43 patients tested. These findings emphasize the need for long-term follow-up of endocrine and metabolic parameters in young patients after BMT in order to offer proper treatment and improve quality of life...
- Late endocrine, metabolic and skeletal sequelae following treatment of childhood cancerHelena K Gleeson
Department of Endocrinology, Christie Hospital, Wilmslow Road, Manchester, Withington, M20 4BX, UK
Best Pract Res Clin Endocrinol Metab 16:335-48. 2002..In this review we consider the following potential problems: growth hormone deficiency and replacement in adulthood, cardiovascular risk factors, osteopaenia, thyroid and parathyroid dysfunction...
- Endocrine abnormalities in patients with Fanconi anemiaNeelam Giri
Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Boulevard EPS 7024, Rockville, Maryland 20852, USA
J Clin Endocrinol Metab 92:2624-31. 2007..Fanconi anemia (FA) is an inherited disorder with chromosomal instability, bone marrow failure, developmental defects, and a predisposition to cancer. Systematic and comprehensive endocrine function data in FA are limited...
- Endocrine late effects from multi-modality treatment of neuroblastomaH M van Santen
Department of Paediatric Endocrinology, Emma Children s Hospital AMC, G8 205, Academic Medical Center AMC, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Eur J Cancer 41:1767-74. 2005..We recommend that during follow-up of neuroblastoma children, special attention should be paid to their endocrine state...
- Endocrine sequelae of cancer therapy in childhoodF B Diamond
Department of Pediatrics University of South Florida College of Medicine, Tampa, USA
J Endocrinol Invest 24:648-58. 2001..These include effects on growth, puberty, fertility, thyroid and adrenal function which may present many years after the successful treatment of underlying disease...
- Admission and discharge guidelines for the pediatric patient requiring intermediate careDavid G Jaimovich
Hope Children s Hospital, Oak Lawn, IL, USA
Crit Care Med 32:1215-8. 2004..This level of care may enhance the efficiency of care and improve the healthcare affordability for patients receiving intermediate care...
- The late effects of childhood cancer therapyJoseph D Dickerman
University of Vermont College of Medicine, Department of Pediatrics, 89 Beaumont Ave, Given D201, Burlington, VT 05405 0068, USA
Pediatrics 119:554-68. 2007..A table listing radiation-therapy site and chemotherapeutic agents and selected late effects that result from their use is provided. Finally, a brief recommendation regarding the establishment of a late-effects clinic is also presented...
- [Etiology and blood pressure patterns in secondary hypertension in children]Cristina Gavrilovici
Clinica a IV a Pediatrie, Facultatea de Medicina, Universitatea de Medicină şi Farmacie Gr T Popa, Iasi
Rev Med Chir Soc Med Nat Iasi 111:70-81. 2007..10%), with a probability of identifying an underlying disease inversely related with the age and directly related with the severity of hypertension...
- Opiate drug use: a potential contributor to the endocrine and metabolic complications in human immunodeficiency virus diseaseOdelia B Cooper
Division of Endocrinology and Metabolism, Johns Hopkins University, Baltimore, Maryland, USA
Clin Infect Dis 37:S132-6. 2003..Although much of the evidence should be viewed as preliminary, these potential abnormalities should be kept in mind when treating opiate-dependent patients infected with HIV...
- Prevalence of endocrine complications and short stature in patients with thalassaemia major: a multicenter study by the Thalassaemia International Federation (TIF)Vincenzo De Sanctis
Department of Reproduction and Growth, Pediatric and Adolescent Unit, Arcispedale S Anna, Ferrara, Italy
Pediatr Endocrinol Rev 2:249-55. 2004..In conclusion, since iron overload and liver damage seem to be the most important factors responsible for endocrine complications, adequate compliance to chelation therapy and rigid precautions against liver infections are imperative...
- [Severe chronic anemia and endocrine disorders in children]Michael Hauschild
Unité d endocrinologie diabétologie pédiatrique, Département médico chirurgical de pédiatrie, CHUV, 1011 Lausanne
Rev Med Suisse 3:988-91. 2007..Diabetes mellitus, hypothyroidism and hypoparathyroidism may also develop. Follow-up includes close monitoring of growth and pubertal development in order to guide therapeutic interventions...
- The pre-operative endocrine assessment of craniopharyngiomasNeil Hopper
Department of Paediatric Endocrinology, St George s Hospital, London, UK
J Pediatr Endocrinol Metab 19:325-7. 2006..We review the available published data on pre-operative endocrine dysfunction and suggest an approach to assessment and management before surgery...
- Endocrine gland abnormalities in thalassemia major: a brief reviewSakineh Mohammadian
Department of Pediatrics, Golestan University of Medical Sciences, Gorgan, Iran
J Pediatr Endocrinol Metab 16:957-64. 2003..In this article we briefly review the current understanding of endocrine gland abnormalities, primarily caused by iron overload, in patients with thalassemia major...
- Low bone mineral density in adolescents with beta-thalassemiaMaria G Vogiatzi
Department of Pediatrics, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, New York 10021, USA
Ann N Y Acad Sci 1054:462-6. 2005..Thus, calcium and vitamin D supplementation with antiresorptive therapies should be evaluated in the adolescent Thal pt with close monitoring of growth and sexual development...
- Comparison of oral and subcutaneous iron chelation therapies in the prevention of major endocrinopathies in beta-thalassemia major patientsChung Hsing Wang
Department of Pediatrics, China Medical University Hospital, Taichung, Taiwan
Hemoglobin 30:257-62. 2006....
- Endocrinological late effects following radiotherapy and chemotherapy of childhood brain tumoursMarianne Schmiegelow
Department of Endocrinology, Abdominal Centre, University Hospitality, H S Rigshospitalet, Copenhagen, Denmark
Dan Med Bull 53:326-41. 2006
- Update on autoimmune polyendocrine syndromes (APS)Corrado Betterle
Clinical Immunology and Allergology, Department of Medical and Surgical Sciences, University of Padua, Padua, Italy
Acta Biomed 74:9-33. 2003....
- [Werner's syndrome and endocrine disorders]B Zantour
Service de Médecine Interne et Endocrinologie, CHU Tahar Sfar, Mahdia, Tunisie
Ann Endocrinol (Paris) 64:205-9. 2003..Thus, in Werner's syndrome metabolic and endocrinologic investigation is necessary in order to treat these disorders and improve the patient's prognosis and life...
- Clinical uses and misuses of dehydroepiandrosteroneEmanuela Binello
Harvard MIT Division of Health Sciences and Technology, Cambridge, MA 02139, USA
Curr Opin Pharmacol 3:635-41. 2003..Research is ongoing at both the basic and the clinical level to elucidate mechanisms of action and establish efficacy and safety, as well as to expand new areas of potential application for this multi-faceted hormone...
- Endocrine and metabolic manifestations of invasive fungal infections and systemic antifungal treatmentMichail S Lionakis
Department of Infectious Diseases, Infection Control and Employee Health, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Mayo Clin Proc 83:1046-60. 2008..If clinicians are equipped with better knowledge of the endocrine and metabolic complications of fungal infections and antifungal therapy, they can more readily recognize them and favorably affect outcome...
- Drug-induced endocrine and metabolic disordersRonald C W Ma
Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
Drug Saf 30:215-45. 2007....
- Endocrine and metabolic adverse effects of psychotropic medications in children and adolescentsChristoph U Correll
The Zucker Hillside Hospital, Psychiatry Research, 75 59 263rd Street, Glen Oaks, NY 11004, USA
J Am Acad Child Adolesc Psychiatry 45:771-91. 2006..Endocrine and metabolic adverse effects are among the most concerning adverse effects of commonly used psychotropic medications...
- Medical causes of headache in childrenNicholas S Abend
Department of Neurology, The University of Pennsylvania School of Medicine, and Children s Hospital of Philadelphia, 34th Street and Civic Center Boulevard, Philadelphia, PA 19104, USA
Curr Pain Headache Rep 11:401-7. 2007..Medical causes of headache are so diverse that uniform screening tests are not useful. History and examination must guide the differential diagnosis, and management plans must be individualized...
- Indications for synergetic and antagonistic effects between trace elements in the environment to human healthJasmina Obhodas
Experimental Physics Department, Institute Ruder Boskovic, Zagreb, Croatia
Coll Antropol 31:209-19. 2007..The results reported here emphasize the importance of the observation of the mutual effects of the environmental variables on the human health for the identification of their synergetic as well as antagonistic effects...
- Recognition and treatment of endocrine/metabolic emergencies in children: part IMichael S Kappy
University of Colorado Health Sciences Center, The Children s Hospital, Denver, USA
Adv Pediatr 49:245-72. 2002..Prompt diagnosis depends on the collection of critical and archival laboratory specimens before the administration of nonspecific therapy...
- Tremor in childrenMohammad K Uddin
Department of Neurology, University of Iowa, Iowa City, IA 52242, USA
Semin Pediatr Neurol 10:26-34. 2003..This review covers the etiology, clinical features, and treatment of the major tremor syndromes in children, and when appropriate, makes comparisons with similar disorders in adults...
- Late health effects of childhood nasopharyngeal radium irradiation: nonmelanoma skin cancers, benign tumors, and hormonal disordersCécile M Ronckers
Department of Ear, Nose and Throat Medicine, Reinaert Kliniek, Maastricht, The Netherlands
Pediatr Res 52:850-8. 2002..0-2.1). We found no evidence of highly elevated risk of benign head and neck tumors, nonmelanoma skin cancer, thyroid disorders, or indicators of pituitary radiation damage after childhood NRI in The Netherlands...
- Pediatric thyroid testing issuesMark D DeBoer
Department of Pediatrics, Division of Endocrinology, University of Virginia, VA, USA
Pediatr Endocrinol Rev 5:570-7. 2007..Additionally, heterophile and anti-T4 or anti-TSH antibodies can interfere with accurate T4 or TSH measurement...
- Impact of thalassemia major on patients and their familiesJ Jaime Caro
Caro Research Institute, Concord, MA 07142, USA
Acta Haematol 107:150-7. 2002..To describe the burden of thalassemia major and its treatment, in terms of prevalence of iron-overload-related complications, direct and indirect costs, and the patient's physical and social well-being...
- Endocrine manifestations of chromosome 22q11.2 microdeletion syndromeJin Ho Choi
Department of Pediatrics, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Horm Res 63:294-9. 2005..2 microdeletion syndrome. This study was undertaken to examine the frequencies and clinical features of endocrine abnormalities in patients with 22q11.2 microdeletion syndrome...
- [Adverse effects of psychotropic agents]Toshimi Owashi
Department of Psychiatry, Showa University School of Medicine
Nihon Rinsho 65:247-53. 2007
- Sleep apnea and sports performanceHelene A Emsellem
The Center for Sleep and Wake Disorders, 5454 Wisconsin Avenue, Suite 1725, Chevy Chase, MD 20815, USA
Clin Sports Med 24:329-41, x. 2005..A high index of suspicion for apnea should exist, particularly in those who have anatomic features and symptoms consistent with the disorder. This article reviews pathophysiology, diagnostic modalities, and treatment interventions...
- [New advances in drug therapy in 2003-2004]A J Scheen
Universite de Liege, Service de Médecine interne générale et Service de Diabétologie, Nutrition et Maladies Metaboliques, Departement de Medecine
Rev Med Liege 59:385-402. 2004..Most of them are currently studied in order to further demonstrate their potential benefit on a long-term basis, in large cohort of patients and using hard clinical endpoints...
- Endocrine complications of neoplastic diseases in children and adolescentsH K Gleeson
Department of Endocrinology, Christie Hospital, Wilmslow Road, Withington, Manchester M20 4BX, UK
Curr Opin Pediatr 13:346-51. 2001....
- Drosophila melanogaster as a model system for drug discovery and pathway screeningSanjay Tickoo
Department of Genetics, University of Cambridge, UK
Curr Opin Pharmacol 2:555-60. 2002....
- Endocrine and metabolic deficiencyGregory F Wu
Department of Neurology, University of Pennsylvania School of Medicine, 3 E Gates Building, 3400 Spruce Street, Philadelphia, PA 19104, USA
Ophthalmol Clin North Am 17:427-34, vii. 2004....
- [The numbers of patients with endocrine disorders are increasing. Who will be responsible for them in the future?]Mann Klaus
Klinik fur Endokrinologie, Universitatsklinikum Essen
MMW Fortschr Med 148:25-6. 2006
- Critical issues in endocrinologyPhilip A Goldberg
Section of Endocrinology, Yale University School of Medicine, TMP 534, 333 Cedar Street, New Haven, CT 06520, USA
Clin Chest Med 24:583-606, vi. 2003..Other endocrine issues that are related to intensive care, such as intensive insulin therapy, relative adrenal insufficiency, and thyroid function test abnormalities are also covered in detail...
- A prospective cohort study of late sequelae of pediatric allogeneic hematopoietic stem cell transplantationWing Leung
Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, Tennessee 38105 2794, USA
Medicine (Baltimore) 86:215-24. 2007..2%, and male hypogonadism 20.3%. Coexistence of multiple late sequelae was common in HSCT survivors. Our findings provide a basis for more effective patient counseling, optimal surveillance, and early intervention...
- [Hormone therapies in pregnancy]G A Tommaselli
Dipartimento di Ginecologia, Ostetricia e Fisiopatologia della Riproduzione Umana, Universita Degli Studi Di Napoli, Federico II, Napoli, Italy
Minerva Ginecol 54:145-50. 2002..In this review, the incidence of the main endocrine disorders, their evolution during pregnancy, their effects on mothers and fetuses and new acquisition on the treatment during pregnancy are discussed...
- Hypothalamic dysfunction and neuroendocrine and metabolic alterations in Huntington's disease: clinical consequences and therapeutic implicationsN A Aziz
Department of Neurology, Leiden University Medical Centre, Leiden, The Netherlands
Rev Neurosci 18:223-51. 2007....
- Endothelial dysfunction in endocrine diseaseT A Abdu
Dept of Medicine, School of Postgraduate Medicine, Keele University, Staffordshire, ST4 7QB, Keele, UK
Trends Endocrinol Metab 12:257-65. 2001....
- Endocrine and growth features in childhood craniopharyngioma: a mono-institutional studyEliana di Battista
Auxoendocrinological Centre, Paediatric Department, University of Genoa, School of Medicine, Italy
J Pediatr Endocrinol Metab 19:431-7. 2006..To evaluate growth and endocrine features in children with craniopharyngioma who were treated and followed up by a single institution between 1976 and 2004...
- Late sequela after treatment of childhood low-grade gliomas: a retrospective analysis of 69 long-term survivors treated between 1983 and 2003Martin Benesch
Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, Medical University of Graz, Graz, Austria
J Neurooncol 78:199-205. 2006..As long-term survival is excellent in patients with low-grade gliomas except for tumors located in the brainstem, future treatment studies should focus on avoiding long-term late effects...
- Nonmalignant late effects after allogeneic stem cell transplantationGerard Socie
Hematology Stem Cell Transplantation, Hopital Saint Louis, Paris, France
Blood 101:3373-85. 2003
- Definable somatic disorders in overweight children and adolescentsThomas Reinehr
Vestische Hospital for Children and Adolescents, University of Witten Herdecke, Datteln, Germany
J Pediatr 150:618-22, 622.e1-5. 2007..To analyze the frequencies and clinical presentation of definable somatic disorders in children who are overweight...
- Atypical psychotropic medications and their adverse effects: a review for the African-American primary care physicianRahn Kennedy Bailey
University of Texas Medical School at Houston, USA
J Natl Med Assoc 95:137-44. 2003..A particular focus will address the increasing concern that these new medications can produce hyperglycemia and diabetes mellitus...
- Long-term endocrine effects of cancer treatment: experience of the Royal Children's Hospital, MelbourneR Hameed
Department of Endocrinology and Diabetes, Royal Children s Hospital, Melbourne, Victoria, Australia
J Paediatr Child Health 41:36-42. 2005..To evaluate the frequency and degree of severity of endocrine late effects in patients treated for childhood cancer and to assess the value of the late effects clinic for continued monitoring of these patients...
- Posterior ocular malformations in children: somatic, neuroradiological and cognitive aspectsK Tear Fahnehjelm
Department of Clinical Science, Division of Paediatric Ophthalmology, Karolinska Institutet, Huddinge University Hospital, Stockholm, Sweden
Acta Paediatr 92:301-8. 2003..To investigate associated neurological, endocrinological and cognitive dysfunctions in children with visual impairment caused by optic nerve hypoplasia or optic nerve/fundus coloboma and/or microphthalmus...
- Late-effects among survivors of leukaemia and lymphoma during childhood and adolescenceLeslie L Robison
Division of Pediatric Epidemiology and Clinical Research, University of Minnesota Cancer Center, Minneapolis, MN, USA
Br J Haematol 122:345-59. 2003
- Endocrine and cardiovascular late effects among adult survivors of childhood brain tumors: Childhood Cancer Survivor StudyJames G Gurney
Department of Pediatrics, University of Minnesota, Minneapolis, Minnesota, USA
Cancer 97:663-73. 2003....
- Pesticides and childrenVincent F Garry
Department of Laboratory Medicine and Pathology and Program in Toxicology, University of Minnesota School of Medicine, Minneapolis, MN 55455, USA
Toxicol Appl Pharmacol 198:152-63. 2004..The level of consensus among these studies is examined. Current concerns regarding neurobehavioral toxicity and endocrine disruption in juxtaposition to the relative paucity of toxicant mechanism-based studies of children are explored...
- Sexual symptoms in endocrine diseases: psychosomatic perspectivesGiancarlo Balercia
Endocrinology, Andrology Unit, Department of Clinical Medicine and Applied Biotechnologies, Polytechnic University of Marche, Ancona, Italy
Psychother Psychosom 76:134-40. 2007..may have a greater or lesser effect on sexual function...
- Endocrine abnormalities in patients with frontoethmoidal encephalomeningocele. A preliminary studyS Wacharasindhu
Endocrine Unit, Department of Pediatrics, Chulalongkorn Memorial Hospital, Chulalongkorn University, Bangkok, Thailand
Horm Res 64:64-7. 2005..Frontoethmoidal encephalomeningocele (FEEM) is a congenital neural tube defect which is more common in Southeast Asia. Its etiology is unknown. No one has ever reported endocrine abnormalities in this condition...
- Craniopharyngioma radiotherapy: endocrine and cognitive effectsThomas E Merchant
Division of Radiation Oncology, St Jude Children s Research Hospital, 332 North Lauderdale Street, Memphis, TN 38104, USA
J Pediatr Endocrinol Metab 19:439-46. 2006..Early and accurate evaluation of these functions should be considered for all patients to provide parents and caregivers with the information necessary to plan intervention and mitigate the consequences of tumor and treatment...
- Gender differences in GAD antibody-positive diabetes mellitus in relation to age at onset, C-peptide and other endocrine autoimmune diseasesEero Lindholm
Department of Endocrinology, University Hospital, Malmo, Sweden
Diabetes Metab Res Rev 20:158-64. 2004....
- The hepatitis C virus infection as a systemic diseaseAnna Linda Zignego
Department of Internal Medicine, Center for Systemic Manifestations of Hepatitis Viruses MASVE, University of Florence, Largo Brambilla 3, 50134, Florence, Italy
Intern Emerg Med 7:S201-8. 2012..The possibility that HCV may be eradicated following antiviral therapy is important for both the therapeutic and preventive points of view, making the HCV disease an ideal model for pathogenetic studies...
- β-thalassemia intermedia: a clinical perspectiveKhaled M Musallam
Department of Medicine and Medical Specialties, IRCCS Cà Granda Foundation Maggiore Policlinico Hospital, 20122 Milan, Italy
Cold Spring Harb Perspect Med 2:a013482. 2012..The effects of some therapeutic interventions on the development of clinical complications are also discussed...
- Endocrine manifestations of Langerhans cell histiocytosis diagnosed in adultsM S García Gallo
Endocrinology Division, Hospital Carlos G Durand, Av Díaz Vélez 5040, Buenos Aires, C1405DCR, Argentina
Pituitary 13:298-303. 2010..Three cases were treated with chemotherapy; one of them had already received radiation therapy on the hypothalamic-pituitary region, developing post-radiation hypopituitarism...
- Optimizing potential for fertility: fertility preservation considerations for the pediatric endocrinologistPeter A Lee
Department of Pediatrics, Penn State College of Medicine, The Milton S Hershey Medical Center, Hershey, PA 17033 0850, USA
Endocrinol Metab Clin North Am 38:761-75. 2009..For adolescent subjects who have sufficient gonadal development and reserve, sperm, oocytes, and ovarian cortex can be retrieved as among adults...
- Dynamic tests in the diagnosis and differential diagnosis of Cushing's syndromeD G Morris
Department of Endocrinology, St Bartholomew s Hospital, London, UK
J Endocrinol Invest 26:64-73. 2003....
- Conservative treatment of chronic pancreatitisAsif Khalid
Department of Medicine, Division of Gastroenterology, Hepatology, and Nutrition, University of Pittsburgh, 3550 Terrace Street, Pittsburgh, PA 15261, USA
Eur J Gastroenterol Hepatol 14:943-9. 2002..The good news is that the understanding of the underlying pathophysiological mechanisms is now advancing rapidly, and hopefully patient-specific and highly effective therapies will become available in the near future...
- Antipsychotics in children and adolescents: increasing use, evidence for efficacy and safety concernsBenedetto Vitiello
National Institute of Mental Health, Room 7147, 6001 Executive Blvd, Bethesda, MD 20892 9633, USA
Eur Neuropsychopharmacol 19:629-35. 2009..Research is also needed to understand the mechanisms underlying antipsychotic-induced toxicities in order to develop effective preventive and treatment strategies...
- [Endocrine disorders and the heart]Onno E Janssen
Klinik fur Endokrinologie, Zentrum fur Innere Medizin, Universitatsklinikum Essen, Universitat Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Deutschland
Internist (Berl) 48:246-54. 2007..The same holds true for long-standing hyperparathyroidism. Recent prospective studies did not confirm the protective effect of hormone replacement therapy on cardiovascular disease...
- Hypothalamic obesity: prevalence, associations and longitudinal trends in weight in a specialist adult neuroendocrine clinicCaroline A Steele
Department of Obesity and Endocrinology, University of Liverpool, Liverpool, UK
Eur J Endocrinol 168:501-7. 2013....
- From diarrhea to obesity in prohormone convertase 1/3 deficiency: age-dependent clinical, pathologic, and enteroendocrine characteristicsRobert H J Bandsma
Divisions of Gastroenterology, Hepatology and Nutrition Pathology Endocrinology, The Hospital for Sick Children Department of Physiology, Faculty of Medicine, University of Toronto, Toronto, ON Alberta Children s Hospital Intestinal Rehabilitation Program, Alberta Children s Hospital and University of Calgary, Calgary, AB, Canada Department of Pediatrics, Mattel Children s Hospital, David Geffen School of Medicine at the University of California, Los Angeles, CA
J Clin Gastroenterol 47:834-43. 2013..The aim of this report is to delineate the clinical, pathologic, and enteroendocrine (EE) features of prohormone convertase 1/3 (PC1/3) deficiency in children...
- An endocrinopathy characterized by dysfunction of the pituitary-adrenal axis and alopecia universalis: supporting the entity of a triple H syndromeK Ichiki
Division of Endocrinology and Metabolism, Department of Medicine, Jichi Medical School, Tochigi 329 0498, Japan
Eur J Endocrinol 147:357-61. 2002..The present finding strongly supports a clinical entity of triple H syndrome, including ACTH deficiency, alopecia universalis and anterograde amnesia, and that there may be some variation of the triad among the subjects...
- Candida and human diseaseA G Palma-Carlos
C A I C Clinical Allergy and Immunology Center
Eur Ann Allergy Clin Immunol 36:291-6. 2004..A general review on candida and human disease emphasizing Candida Species, clinical manifestations, immune response NK failure and immunotherapy...
- [Vasoactive polypeptides and cardiovascular endocrine diseases]Zheng pei Zeng
Department of Endocrinology, PUMC Hospital, CAMS and PUMC, Beijing 100730, China
Zhongguo Yi Xue Ke Xue Yuan Xue Bao 27:443-5. 2005..New advances have been increasingly achieved in basic and clinical researches. It has become one of the most active areas in life sciences...
- [Genetic testing and gene-based testing for endocrine disorders]Toshihiko Yanase
Department of Medicine and Bioregulatory Science Third Department of Internal Medicine, Graduate School of Medical Sciences, Kyushu University
Nihon Rinsho 63:207-11. 2005
- Late effects of treatment in survivors of childhood acute myeloid leukemiaW Leung
After Completion of Therapy Program, St Jude Children s Research Hospital, Memphis, TN 38105, USA
J Clin Oncol 18:3273-9. 2000..To investigate the incidence of and risk factors for late sequelae of treatment in patients who survived for more than 10 years after the diagnosis of childhood acute myeloid leukemia (AML)...
- Genetic strain differences in learned fear inhibition associated with variation in neuroendocrine, autonomic, and amygdala dendritic phenotypesMarguerite C Camp
Laboratory of Behavioral and Genomic Neuroscience, NIAAA, Bethesda, MD, USA
Neuropsychopharmacology 37:1534-47. 2012..Collectively, these data provide convergent support for the utility of the S1 strain as a tractable model for elucidating the neural, molecular and genetic basis of persistent, excessive fear...
- Growth, final height and endocrine sequelae in a UK population of patients with Hurler syndrome (MPS1H)Chris J Gardner
Royal Manchester Children s Hospital, Manchester, UK
J Inherit Metab Dis 34:489-97. 2011..Regular screening for the development of endocrine sequelae is therefore essential. We present for the first time data on final adult height and endocrine complications in children with MPSIH post HSCT...
- Hyperestrogenemia simulating kennedy diseaseJin Jun Luo
Departments of Neurology and Pharmacology, Temple University School of Medicine, Philadelphia, PA
J Clin Neuromuscul Dis 9:291-6. 2007..Splenomegaly was present by ultrasound. The increased level of estrogen adversely affected estrogen-sensitive cells in breast, testicular, neuronal, and muscle cells, leading to the clinical phenotype...
- [Structural CNS abnormalities responsible for coincidental occurrence of endocrine disorders, epilepsy and psychoneurologic disorders in children and adolescents]Jerzy Starzyk
Klinika Endokrynologii Dzieci i Młodziezy, Katedra Pediatrii, Polsko Amerykanski Instytut Pediatrii, Uniwersytet Jagielloński Collegium Medicum, Krakow
Przegl Lek 67:1120-6. 2010..However, structural central nervous system (CNS) abnormalities that cause both endocrine and neurologic disorders seem to be markedly less common. No reports addressing this problem are available in the literature...
- Endocrine alterations around the time of abortion in mares impregnated with donkey or horse semenM Boeta
Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autonoma de Mexico, Mexico, DF
Anim Reprod Sci 121:124-30. 2010..Deficiency of eCG may be a primary cause of many of these cases, either by failing to stimulate enough luteal progesterone secretion and/or by failing to protect the corpora lutea (CL) of pregnancy from endogenous PGF2alpha secretion...
- Endocrine function in multiple sclerosisP Klapps
Neurology Clinic, Steglitz Clinic, Free University of Berlin, Germany
Acta Neurol Scand 85:353-7. 1992..However, the poststimulatory secretion of cortisol, growth hormone or thyroid-stimulating hormone was impaired in 7/31 patients, suggesting a possible preclinical endocrine insufficiency in these patients...
- Endocrine hypertension--current understanding and comprehensive management reviewNorlela Sukor
Endocrine Unit, Department of Medicine, Universiti Kebangsaan Malaysia Medical Center, Jalan Yaacob Latif, 56000 Cheras, Kuala Lumpur, Malaysia
Eur J Intern Med 22:433-40. 2011....
- Endocrine disorders associated with inappropriately high aromatase expressionS E Bulun
Cecil H and Ida Green Center for Reproductive Biology Sciences and Department of Obstetrics Gynecology, University of Texas Southwestern Medical Center, Dallas 75235 9051, U S A
J Steroid Biochem Mol Biol 61:133-9. 1997..3 and II in all of the above tissues. This article describes the common pathophysiological and molecular features of excessive aromatase expression in these disease states...
- A Secular Change in Menstrual Characteristicis of Adult and Midlife Women?Sioban D Harlow; Fiscal Year: 2010....
- Androgen deficiency and Osteopenia in Anorexia NervosaKaren Miller; Fiscal Year: 2002..In the third phase of the study, we will examine the effects of administering testosterone on bone density and body mass. ..
- Mitochondria and surgical myopreservation in agingArshad Jahangir; Fiscal Year: 2006..This is especially relevant for cardiac surgery in the elderly, with the ultimate goal of limiting post-bypass pump failure. ..
- Staging Reproductive Aging in Four Cohorts: Issues of Hormone Use Spotting BiasSioban Harlow; Fiscal Year: 2009..Results will facilitate clinical decision making for women and providers relevant to contraception, symptomatic treatment and preventive therapy. ..
- Population-Based Reference Ranges for TestosteroneVASAN S RAMACHANDRAN; Fiscal Year: 2010..These steps will facilitate the development of rational criteria for classifying men into androgen-deficient and androgen-replete categories. ..
- Testosterone:Physical Function in Men on HemodialysisShalender Bhasin; Fiscal Year: 2004..Therefore, if successful, this study should help identify a therapeutic intervention that might improve physical function and reduce disability in men with end stage renal disease. ..
- Mechanisms of Testosterone Effects on Body CompositionShalendar Bhasin; Fiscal Year: 2007..abstract_text> ..
- Function and structure of pendrin in thyroid cellsPeter Kopp; Fiscal Year: 2007..These studies will provide fundamental insights into the (patho)physiology of this novel anion transporter that has important functions in the thyroid, the kidney and the inner ear. ..
- TESTOSTERONE REPLACEMENT & PHYSICAL FUNCTION IN HIV+MENShalender Bhasin; Fiscal Year: 2005..This study should help identify a therapeutic intervention that might improve physical function in HIV-infected men with weight loss, and enhance our understanding of the mechanisms by which testosterone stimulates muscle accretion. ..
- Role of 5-alpha Reductase in Testosterone ActionsShalendar Bhasin; Fiscal Year: 2007..abstract_text> ..
- Testosterone Modulation of Response to Phosphodiesterase InhibitorsShalendar Bhasin; Fiscal Year: 2009....
- SARCOPENIA--TESTOSTERONE DOSE RESPONSE IN OLDER MENShalender Bhasin; Fiscal Year: 2002....
- Ethnic Differences in Survival after Childhood ALLSmita Bhatia; Fiscal Year: 2009..abstract_text> ..
- Lapatinib in childhood CNS malignanciesMaryam Fouladi; Fiscal Year: 2006..These data will be used in the rational design of future phase I combination or frontline studies to improve the outcome in children with these poor prognosis tumors. [unreadable] [unreadable]..
- Colon Cancer Inhibition by a Class of PPARgamma AgonistsStephen Safe; Fiscal Year: 2009..The proposed studies will provide mechanistic insights on PPARy-dependent inhibition of colon cancer and identify compounds for future clinical studies. ..
- PREMATURE MENOPAUSE IN SURVIVORS OF CHILDHOOD CANCERCharles Sklar; Fiscal Year: 2002..The large size of the study population, the heterogeneity of diagnoses and exposures, combined with the extensive treatment data, will allow assessment of interaction between the major risk factors of interest. ..
- MN REGIONAL SLEEP DISORDERS CENTER SLEEP ACADEMIC AWARDGerald Rosen; Fiscal Year: 2002....
- PROSTATIC STEROIDS AND SECOND MESSENGERSWilliam Rosner; Fiscal Year: 2001....
- Cell Fate Determination of the Intestine and Chronic Diarrhea in ChildrenMartin Martin; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- DETERMINANTS OF TISSUE ESTRADIOL SENSITIVITYRichard Santen; Fiscal Year: 2009..FTS, a novel mTOR inhibitor will be used in vitro to activate the stress kinase pathway and apoptosis. In vivo, FTS will be used to enhance estradiol induced apoptosis in nude mice. ..
- Human Subjects Research Enhancements ProgramsWilliam Rosner; Fiscal Year: 2002..All such monthly reviews and quizzes will be archived for review. All of the above activities will be designed to be continued after the completion of the initial year of support. ..
- Regulation of Intestinal Nutrient TransportersMartin Martin; Fiscal Year: 2002..The identification and further characterization of these cis elements will provide better insight into the molecular mechanism of enterocyte-specific cell fate and the various factors mediating its regulation. ..
- Chaperones, ROS systems, & IGF-1:Roles in vascular agingDavid Clemmons; Fiscal Year: 2008..abstract_text> ..
- D-Cycloserine Augmentation of Therapy for Pediatric Obsessive-Compulsive DisorderEric Storch; Fiscal Year: 2007..Such agents may have utility in improving outcome, reducing premature therapy termination, and targeting patients who have been treatment refractory. [unreadable] [unreadable] [unreadable]..
- PROGESTERONE THERAPY FOR WOMEN WITH EPILEPSYAndrew Herzog; Fiscal Year: 2008..30 x .35) 100,000 women with catamenial epilepsy and perhaps many more women with no a priori demonstrated hormonal sensitivity to seizure occurrence. ..
- Epidemiology of Cancer and Mental Illness in Rural AreasCaroline Carney Doebbeling; Fiscal Year: 2005..abstract_text> ..
- Neuroendocrine outcomes of prenatal PCB exposuresANDREA GORE; Fiscal Year: 2005..The results should have important implications for understanding consequences of, and developing therapies for, exposures of wildlife and humans to EDCs such as PCBs. ..
- EXTRAMURAL RESEARCH FACILITIES IMPROVEMENTRussell Joffe; Fiscal Year: 2004..No funds are sought for basic science research laboratories or any clinical areas in the Cancer Center. ..
- Evaluation of Vitamin D Requirements During PregnancyBruce Hollis; Fiscal Year: 2007..unreadable] [unreadable]..
- Regulation of VEGF/HIF-1 by AKT: Implications for RadiotherapyAmit Maity; Fiscal Year: 2010..Increased oxygenation should make tumors more sensitive to radiation;therefore, our studies may be important in helping to optimize the combination of EGFR inhibitors with radiation. ..
- Fetal Programming of Early DevelopmentCURT ALAN SANDMAN; Fiscal Year: 2010..Prenatal influences of CRH on HPA reactivity (Aim 4) will be evaluated by assessing salivary cortisol at rest and after mild stress. These studies in children are the first to examine the role of prenatal CRH on human development. ..
- Establishing the Vitamin D Requirements During LactationBruce W Hollis; Fiscal Year: 2010..The findings of this study will generate important new information for health care professionals and policy makers with regard to vitamin D requirements and the potential benefit to both mother and infant. ..
- PTHrP on normal osteoblast differentiation and functionRAMIRO TORIBIO; Fiscal Year: 2008..Dr. Thomas Rosol's laboratory will provide an excellent environment for developing the skills necessary to become a successful independent researcher. ..
- FANCONI ANEMIA--HETEROGENEITY AND CARRIER DETECTIONARLEEN AUERBACH; Fiscal Year: 2007..This will be combined with functional complementation[unreadable] in an effort to accelerate the identification of these genes.[unreadable] [unreadable]..
- IGFBP5 AND INTEGRINS AND CONTROLLING IGF1 ACTIONSDavid Clemmons; Fiscal Year: 2002....
- STRESS AND BIRTH OUTCOMESCurt Sandman; Fiscal Year: 2001..The study design and analytic methods allows for estimation of the unique effects of CRH and psychosocial stress on the length of gestation. ..
- ALKYL PCDFS--INHIBITION OF MAMMARY CANCERStephen Safe; Fiscal Year: 2001..Thus the proposed studies will define a new mechanism-based class of antiestrogens that can be used alone or in combination with tamoxifen for treatment of breast and endometrial cancer. ..
- HEPATITIS C IN CHILDHOOD CANCER SURVIVORSMelissa Hudson; Fiscal Year: 2003..abstract_text> ..
- Peripheral and Central Mechanism of Pain in Patients with FibromyalgiaROLAND M STAUD; Fiscal Year: 2010..Either way, we will provide evidence that will characterize the role of local anesthesia, placebo analgesia, or both. Thus patients with FM and other similar pain syndromes may strongly benefit from the results of our study. ..
- Endocrine Function and Mood in Bipolar DisorderNatalie Rasgon; Fiscal Year: 2008..abstract_text> ..
- CTL2 ELISA: A Diagnostic Test for Autoimmune Hearing LossVijay Kumar; Fiscal Year: 2007..Current diagnostic methods are inadequate to support proper diagnosis AHL; our team proposes to develop a simple, yet precise test to meet this need. [unreadable] [unreadable] [unreadable]..
- CLINICAL SEARCH RETRIEVAL FROM FOUR ELECTRONIC DATABASESR Haynes; Fiscal Year: 2007..g., sensitivity); and evaluating the usefulness of the clinical hedges in the intended users group, clinicians. [unreadable] [unreadable]..
- NEUROBIOLOGIC STUDIES OF THE LIMBIC SYSTEM IN AUTISMMargaret Bauman; Fiscal Year: 2004..Further, studies for evidence of a progressive process, and involvement of selected neurotransmitter systems in the limbic system that have been implicated in the clinical features of autism will be conducted. ..
- Fusion Proteins As Probes of P450 Structure and FunctionRichard Auchus; Fiscal Year: 2004..In addition, this approach might be generally applicable to structural studies of membrane-bound proteins. ..
- Role of the Zic2 gene in CNS development & malformationStephen Brown; Fiscal Year: 2005..In addition, our studies will elucidate the cellular and molecular processes that result in HPE and will therefore be useful in understanding this and other brain malformations. ..
- Effects of Dioxin on Vietnamese CiviliansDavid Carpenter; Fiscal Year: 2004..7. ..
- ARTHEROSCLEROSIS IN INSULIN-RESISTANT, HYPERLIPIDEMIC P*David Clemmons; Fiscal Year: 2005....
- Emergence of SIB in Developmentally Delayed IndividualsCURT ALAN SANDMAN; Fiscal Year: 2010..Findings from this project will contribute to the understanding of the emergence and maintenance of SIB. ..
- REGIONAL BIOCONTAINMENT LABORATORY (RBL) NEWARK CENTERRussell Joffe; Fiscal Year: 2005..When the RBL is operational, it will create a critical mass of biodefense scientists in Newark and serve as a specialized laboratory for emerging regional and national biodefense needs. ..
- Blockade of Anthrax Cytotoxicity Using Furin InhibitorsIris Lindberg; Fiscal Year: 2003..abstract_text> ..
- MECHANISM OF PAIN IN PATIENTS WITH FIBROMYALGIA SYNDROMERoland Staud; Fiscal Year: 2008..In addition, our findings may contribute to the understanding of pain mechanisms related to other chronic pain disorders. ..
- Winter Neuropeptides ConferenceCurt Sandman; Fiscal Year: 2004..The conference is inclusive for all groups. Half of the organizing and steering committees are women. Efforts are made to include minorities and persons with disabilities. ..
- OPIOID PEPTIDE PROCESSING ENZYMESIris Lindberg; Fiscal Year: 2002..Taken together, these experiments should help us to understand the basic biochemistry of the prohormone convertases on opioid peptide precursors as well as the regulation of convertase activity. ..
- ERT, DEPRESSION AND COGNITION IN POSTMENOPAUSAL WOMENNatalie Rasgon; Fiscal Year: 2002..antidepressant alone. This research will be the foundation for a future investigation of pathophysiology of reproductive-related mood disorders. ..
- MOLECULAR BASIS OF ENTEROCYTE REGULATION DURING ONTOGENYMartin Martin; Fiscal Year: 2002..Analysis of the FcRn and pIgR genes offers a unique model that may lead to a better understanding of the molecular mechanism of intestinal ontogeny, and specifically the intrinsic clock which controls its regulation. ..
- ESTROGEN INDUCED RESPONSES VIA ER/SPL COMPLEXESStephen Safe; Fiscal Year: 2002..These results will ultimately facilitate design of chemotherapeutic approaches which target specific genes. ..
- Coactivation of Estrogen Receptor alpha/Sp1Stephen Safe; Fiscal Year: 2006..abstract_text> ..
- Prenatal diagnosis through selective DNA amplificationStephen Brown; Fiscal Year: 2009..When and if such methods become available, they will revolutionize prenatal diagnosis and will represent a major milestone in the improvement of prenatal care. ..
- Small Laboratory Animal Imaging: High Resolution Microcomputed Tomography SystemRAMIRO TORIBIO; Fiscal Year: 2006..Salary and benefits for the Supervisor and Space and utilities for the instrument will be provided by Department of Veterinary Biosciences and the College of Veterinary Medicine. [unreadable] [unreadable]..
- 2,3,7,8,--TCDD Effects on the Estrogenic ResponsesStephen Safe; Fiscal Year: 2006..The proposed Aims will address important mechanistic considerations on IDRE-independent inhibitory AhR-ERa crosstalk and pathways critical for inhibition of mammary tumor growth by SAhRMs. ..
- MECHANISMS BY WHICH IGF-I STIMULATES SMOOTH MUSCLE CELLSDavid Clemmons; Fiscal Year: 2007..The results may suggest novel strategies for interfering with these processes to alter the progression of atherosclerosis. ..