Genomes and Genes
Summary: Fractures of the femur.
Publications310 found, 100 shown here
- Treatment of acute distal femur fractures above a total knee arthroplasty: systematic review of 415 cases (1981-2006)Diego A Herrera
Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, USA
Acta Orthop 79:22-7. 2008..There is no consensus on the best treatment for periprosthetic supracondylar fracture...
- Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for Bone and Mineral ResearchElizabeth Shane
Columbia University, College of Physicians and Surgeons, PH 8 West 864, 630 West 168th Street, New York, NY 10032, USA
J Bone Miner Res 25:2267-94. 2010..The task force defined major and minor features of complete and incomplete atypical femoral fractures and recommends that all major features, including their location in the subtrochanteric region and femoral ..
- Bilateral low-energy simultaneous or sequential femoral fractures in patients on long-term alendronate therapyCraig M Capeci
Department of Orthopaedic Surgery, New York University Hospital for Joint Diseases, 301 East 17th Street, Suite 1401, New York, NY 10003, USA
J Bone Joint Surg Am 91:2556-61. 2009..have associated long-term alendronate therapy with unilateral low-energy subtrochanteric and diaphyseal femoral fractures in a small number of patients...
- Low-energy femoral shaft fractures associated with alendronate useAndrew S Neviaser
Hospital for Special Surgery, New York, NY, USA
J Orthop Trauma 22:346-50. 2008..The purpose of this study is to demonstrate an association between alendronate use and a specific pattern of low-energy femoral shaft fracture...
- Low-energy femoral fractures associated with the long-term use of bisphosphonates: a case series from a Swiss university hospitalKuntheavy Ing-Lorenzini
Division of Clinical Pharmacology and Toxicology, Regional Pharmacovigilance Centre, University Hospitals of Geneva, Geneva, Switzerland
Drug Saf 32:775-85. 2009..Bisphosphonates are effective and well tolerated anti-resorptive drugs used for the treatment of osteoporosis. However, some concerns about their potential long-term negative effects are emerging...
- Atypical femoral fractures are a separate entity, characterized by highly specific radiographic features. A comparison of 59 cases and 218 controlsJörg Schilcher
Orthopedics, Department of Clinical and Experimental Medicine, Faculty of Health Science, Linkoping University, Sweden
Bone 52:389-92. 2013Estimations of the risk of bisphosphonate associated atypical femoral fractures vary between different population-based studies, from considerable to neglectable...
- Effect of a statewide fall prevention program on incidence of femoral fractures in residents of long-term care facilitiesKilian Rapp
Department of Clinical Gerontology, Robert Bosch Hospital, Stuttgart, Germany
J Am Geriatr Soc 58:70-5. 2010To evaluate the effect of a statewide dissemination of a modified evidence-based fall prevention program on incidence of femoral fractures in nursing homes.
- Use of inhaled and oral glucocorticoids, severity of inflammatory disease and risk of hip/femur fracture: a population-based case-control studyF De Vries
Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, The Netherlands
J Intern Med 261:170-7. 2007..Patients using higher dosages of inhaled or oral glucocorticoids (GCs) have an increased risk of hip/femur fractures. The role of the underlying disease in the aetiology of this increased risk has not been widely studied...
- Bisphosphonate use and atypical fractures of the femoral shaftJörg Schilcher
Department of Experimental and Clinical Medicine, Faculty of Health Science, Linkoping University, Linkoping, Sweden
N Engl J Med 364:1728-37. 2011..Studies show conflicting results regarding the possible excess risk of atypical fractures of the femoral shaft associated with bisphosphonate use...
- Locking compression plates for the treatment of periprosthetic femoral fractures around well-fixed total hip and knee implantsGavin C A Wood
Division of Orthopaedic Surgery, Queen s University, Kingston Ontario, Canada
J Arthroplasty 26:886-92. 2011..few published studies examining the use of locking compression plates for the treatment of periprosthetic femoral fractures. Fifteen total hip or knee arthroplasty patients with 16 Vancouver type B1 and C fractures with an average ..
- Increasing occurrence of atypical femoral fractures associated with bisphosphonate useRaphael P H Meier
Department of Surgery, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland
Arch Intern Med 172:930-6. 2012Current evidence suggests that there is an association between bisphosphonate therapy and atypical femoral fractures, but the extent of this risk remains unclear.
- Distal femoral fracture fixation utilizing the Less Invasive Stabilization System (L.I.S.S.): the technique and early resultsP J Kregor
Department of Orthopedic Surgery, University of Mississippi Medical Center, Jackson 39216, USA
Injury 32:SC32-47. 2001The treatment of supracondylar femoral fractures in the past three decades has evolved from non-operative to operative treatment...
- Radiographic and functional results of osteosynthesis using the proximal femoral nail antirotation (PFNA) in the treatment of unstable intertrochanteric femoral fracturesSuner Sahin
Department of Orthopedics and Traumatology, Sisli Etfal Training and Research Hospital, Istanbul
Acta Orthop Traumatol Turc 44:127-34. 2010We evaluated the radiographic and functional results of the proximal femoral nail antirotation (PFNA) system in patients with unstable intertrochanteric femoral fractures.
- Mid-term outcomes after intramedullary fixation of peritrochanteric femoral fractures using the new proximal femoral nail antirotation (PFNA)Yake Liu
Department of Orthopaedics, The Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong City, Jiangsu Province 226001, PR China
Injury 41:810-7. 2010Controversy persists concerning the preferred treatment of peritrochanteric femoral fractures. The purpose of the present study was to evaluate the mid-term outcomes of the newly developed implants - proximal femoral nail antirotation (..
- Importance of screw position in intertrochanteric femoral fractures treated by dynamic hip screwM Guven
The Hospital of University of Abant Izzet Baysal, Department of Orthopaedics and Traumatology, 14280 Bolu, Turkey
Orthop Traumatol Surg Res 96:21-7. 2010..The aim of this retrospective study was to evaluate the position of the screw in the femoral head and its effect on cut-out failure especially in patients with inconvenient tip-apex distance...
- The role and efficacy of retrograding nailing for the treatment of diaphyseal and distal femoral fractures: a systematic review of the literatureG Papadokostakis
Department of Trauma, St James s University Hospital, Beckett Street, Leeds LS9 7TF, UK
Injury 36:813-22. 2005..8 years) who sustained 963 distal and diaphyseal femoral fractures. The overall mortality rate was 5.3%. The incidence of infection was 1...
- The effect of time to definitive treatment on the rate of nonunion and infection in open fracturesBrian J Harley
Division of Orthopaedic Surgery, Department of Surgery, University of Alberta Hospital, Edmonton, Alberta, Canada
J Orthop Trauma 16:484-90. 2002..To determine the association of other clinical determinants with these same adverse events...
- Incidence of stress fractures of the femoral shaft in women treated with bisphosphonateJörg Schilcher
Department of Orthopedics, AIM IKE, Faculty of Health Science, Linkoping University, Linkoping, Sweden
Acta Orthop 80:413-5. 2009..Recent case reports have identified an association between long-term bisphosphonate treatment and stress fractures of the femoral shaft. The risk of such fractures in bisphosphonate users has not been determined...
- Complications of pediatric femur fractures treated with titanium elastic nails: a comparison of fracture typesErnest L Sink
Department of Orthopaedics, University of Colorado Health Science Center, School of Medicine, Denver, CO 80218, USA
J Pediatr Orthop 25:577-80. 2005..The authors conclude that in patients with "length-unstable" femur fractures, consideration should be given to methods of treatment other than titanium flexible intramedullary nails...
- Correlation between IL-6 levels and the systemic inflammatory response score: can an IL-6 cutoff predict a SIRS state?Peter V Giannoudis
Academic Department of Trauma Surgery, Leeds University, Leeds, United Kingdom
J Trauma 65:646-52. 2008..The aim of this study was to investigate, in a group of adult trauma patients, the relationship between the interleukin-6 (IL-6) concentration, the systemic inflammatory response score (SIRS) and outcome...
- Use of flexible intramedullary nails in pediatric femur fracturesChristine Ann Ho
Children s Orthopaedic Center, Children s Hospital Los Angeles, CA, USA
J Pediatr Orthop 26:497-504. 2006..Although the end results are favorable, complications are relatively frequent, particularly in older children...
- Are short femoral nails superior to the sliding hip screw? A meta-analysis of 24 studies involving 3,279 fracturesHenry Wynn Jones
Department of Orthopaedics, Bedford Hospital, Kempston Road, MK42 9DJ, Bedford, UK
Int Orthop 30:69-78. 2006..the sliding hip screw (SHS) and intramedullary nails (IMN) in stable and unstable extracapsular proximal femoral fractures. All randomised controlled studies comparing IMNs with a SHS were considered for inclusion...
- A comparison of the long gamma nail with the sliding hip screw for the treatment of AO/OTA 31-A2 fractures of the proximal part of the femur: a prospective randomized trialTristan M Barton
Department of Trauma and Orthopaedics, Frenchay Hospital, Frenchay Park Road, Frenchay, Bristol BS6 1LE, United Kingdom
J Bone Joint Surg Am 92:792-8. 2010..A prospective, randomized, controlled trial was performed to compare the outcome of treatment of these unstable fractures of the proximal part of the femur with either a sliding hip screw or a long gamma nail...
- Impact of the method of initial stabilization for femoral shaft fractures in patients with multiple injuries at risk for complications (borderline patients)Hans Christoph Pape
Division of Trauma, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Ann Surg 246:491-9; discussion 499-501. 2007....
- Association of low-energy femoral fractures with prolonged bisphosphonate use: a case control studyB A Lenart
Hospital for Special Surgery, New York, NY 10021, USA
Osteoporos Int 20:1353-62. 2009..Further studies are warranted...
- Comparison of titanium elastic nails with traction and a spica cast to treat femoral fractures in childrenJohn M Flynn
Division of Orthopaedics, Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104 4399, USA
J Bone Joint Surg Am 86:770-7. 2004Titanium elastic nails are commonly used to stabilize femoral fractures in school-aged children, but there have been few studies assessing the risks and benefits of this procedure compared with those of traditional traction and ..
- Evolution of the internal fixation of long bone fractures. The scientific basis of biological internal fixation: choosing a new balance between stability and biologyStephan M Perren
AO Research and Development Institutes, Davos, Switzerland
J Bone Joint Surg Br 84:1093-110. 2002..The phenomenon of bone loss and stress protection has a biological rather than a mechanical explanation. The same mechanism of necrosis-induced internal remodelling may explain the basic process of direct healing...
- Should bisphosphonates be continued indefinitely? An unusual fracture in a healthy woman on long-term alendronateJennifer P Schneider
Geriatrics 61:31-3. 2006
- Use of beta-blockers and the risk of hip/femur fracture in the United Kingdom and The NetherlandsF De Vries
Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Universiteit Utrecht, Sorbonnelaan 16, 3584 CA Utrecht, The Netherlands
Calcif Tissue Int 80:69-75. 2007....
- Do sacrificial bonds affect the viscoelastic and fracture properties of bone?Yener N Yeni
Section of Biomechanics, Bone and Joint Center, Department of Orthopaedics and Rehabilitation, Henry Ford Hospital, Detroit, MI 48202, USA
Clin Orthop Relat Res 443:101-8. 2006..These effects were reversible, consistent with the original proposal. However, these effects may not necessarily indicate an increase in strength or toughness of the tissue at the macro scale...
- Femoral fracture fixation in developing countries: an evaluation of the Surgical Implant Generation Network (SIGN) intramedullary nailPatrick Sekimpi
Department of Orthopaedics, Mulago Hospital, P O Box 7051, Kampala, Uganda
J Bone Joint Surg Am 93:1811-8. 2011The Surgical Implant Generation Network (SIGN) intramedullary nailing system was designed to treat femoral fractures in developing countries where real-time imaging, power equipment, and fracture tables are often not available...
- Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral ResearchElizabeth Shane
Author affiliations appear on pp 15 20
J Bone Miner Res 29:1-23. 2014..When BPs are stopped, risk of an AFF may decline. Lower limb geometry and Asian ethnicity may contribute to the risk of AFFs. There is inconsistent evidence that teriparatide may advance healing of AFFs...
- Locked plating of supracondylar periprosthetic femur fracturesThomas M Large
Department of Orthopaedic Surgery, Carolinas Medical Center, PO Box 32861, Charlotte, North Carolina, USA
J Arthroplasty 23:115-20. 2008..Locked plating is a reliable treatment for periprosthetic supracondylar femur fractures. We experienced a lower complication, revision, malunion, and nonunion rate with locked plating versus conventional treatment options...
- Locking plate osteosynthesis for Vancouver Type B1 and Type C periprosthetic fractures of femur: a report on 12 patientsJagannath Chakravarthy
South Birmingham Trauma Unit, Selly Oak Hospital, 1071 Bristol Road South, Birmingham, UK
Injury 38:725-33. 2007..There were no infections. Our experience encourages us that locking plates have a role to play in managing periprosthetic fractures around a stable femoral stem, especially in patients with poor soft tissue and osteoporosis...
- Low infection rates after 34,361 intramedullary nail operations in 55 low- and middle-income countries: validation of the Surgical Implant Generation Network (SIGN) online surgical databaseSven Young
Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
Acta Orthop 82:737-43. 2011..Most operations are reported to the SIGN Online Surgical Database (SOSD). Follow-up has been reported to be low, however. We wanted to examine the pattern of follow-up and to assess whether infection rates could be trusted...
- Atypical femoral fractures and bisphosphonate treatment: experience in two large United Kingdom teaching hospitalsR N Thompson
Royal Victoria Hospital, Department of Trauma and Orthopaedics, Grosvenor Road, Belfast BT12 6BA, UK
J Bone Joint Surg Br 94:385-90. 2012..This large dual-centre review has established the incidence of atypical femoral fractures at 7% of the study population, 81% of whom had been on bisphosphonate treatment for a mean of 4.6 years (0...
- Computerised navigation for closed reduction during femoral intramedullary nailingRami Mosheiff
Department of Orthopaedic Surgery, The Hadassah Hebrew University Medical School, P O Box 12000, Ein Kerem, Jerusalem IL 91120, Israel
Injury 36:866-70. 2005
- The cortical step sign as a tool for assessing and correcting rotational deformity in femoral shaft fracturesJakub S Langer
Department of Orthopedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
J Orthop Trauma 24:82-8. 2010..This study aims to critically analyze the cortical step sign in cadaveric specimens using radiographic and direct measurements...
- Ballistic fractures: indirect fracture to bonePaul J Dougherty
Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, Michigan 48109, USA
J Trauma 71:1381-4. 2011....
- Intraoperative cone-beam CT for correction of periaxial malrotation of the femoral shaft: a surface-matching approachAmal Khoury
Hadassah University Medical Centre, Department of Orthopaedic Surgery, Ein Kerem, Jerusalem 91120
Med Phys 34:1380-7. 2007..49 degrees. CBCT can provide intraoperative high-resolution images with a large field of view. This quality of imaging enables surface matching algorithms to be utilized even with large areas of comminution...
- The effect of bone morphogenetic protein-2, bone morphogenetic protein-7, parathyroid hormone, and platelet-derived growth factor on the proliferation and osteogenic differentiation of mesenchymal stem cells derived from osteoporotic boneIppokratis Pountos
Academic Department of Trauma and Orthopaedics, School of Medicine, University of Leeds, Leeds, UK
J Orthop Trauma 24:552-6. 2010....
- Femoral fractures in adolescents: a comparison of four methods of fixationLeonhard E Ramseier
Hospital for Sick Children, Toronto, Ontario, Canada
J Bone Joint Surg Am 92:1122-9. 2010The optimal management of femoral fractures in adolescents is controversial. This study was performed to compare the results and complications of four methods of fixation and to determine the factors related to those complications.
- Femoral nonunion: risk factors and treatment optionsJoseph R Lynch
Department of Orthopaedics and Sports Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA
J Am Acad Orthop Surg 16:88-97. 2008..b>Femoral fractures may fail to unite because of the severity of the injury, damage to the surrounding soft tissues, inadequate ..
- Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnoverJohn Street
Department of Academic Surgery, National University of Ireland, University College Cork, Cork, Ireland
Proc Natl Acad Sci U S A 99:9656-61. 2002..a soluble, neutralizing VEGF receptor decreased angiogenesis, bone formation, and callus mineralization in femoral fractures. Inhibition of VEGF also dramatically inhibited healing of a tibial cortical bone defect, consistent with ..
- Less invasive stabilisation system (LISS) for the treatment of periprosthetic femoral fractures: a 3-year follow-upPhilipp Kobbe
Department of Orthopaedic Trauma Surgery, Braunschweig, Germany
Injury 39:472-9. 2008..have reported encouraging results with a locked plating system in the management of periprosthetic femoral fractures. However, data on mid- or long-term functional outcome is not available...
- A comparison of the proximal femoral nail antirotation device and dynamic hip screw in the treatment of unstable pertrochanteric fractureY Z Xu
Department of Orthopaedics, First Affiliated Hospital of Soochow University, Suzhou, China
J Int Med Res 38:1266-75. 2010..All fractures in both groups united during follow-up. The PFNA allowed earlier mobilization and faster recovery than the DHS. The PFNA is a highly acceptable, minimally invasive implant for unstable fractures...
- Pediatric femoral fractures: a systematic review of 2422 casesRudolf W Poolman
Department of Orthopaedic Surgery, McMaster University, Hamilton, Ontario, Canada
J Orthop Trauma 20:648-54. 2006The incidence of femoral fractures in children comprise 20 per 100,000 yearly in the United States and Europe. The treatment of femoral shaft fractures in the pediatric population remains controversial...
- Early results of the less invasive stabilization system for mechanically unstable fractures of the distal femur (AO/OTA types A2, A3, C2, and C3)Mark Weight
Harris Methodist Hospital Fort Worth and Fort Worth Affiliated Hospitals John Peter Smith Orthopaedic Surgery Residency, Fort Worth, TX, USA
J Orthop Trauma 18:503-8. 2004..The purpose of this study is to evaluate the clinical results of patients with high energy, mechanically unstable fractures of the distal femur treated with the Less Invasive Stabilization System...
- Titanium elastic nails for pediatric femur fractures: a multicenter study of early results with analysis of complicationsJ M Flynn
Division of Orthopaedics, The Children s Hospitals of Philadelphia, Pennsylvania 19104 4399, USA
J Pediatr Orthop 21:4-8. 2001..As indications, implantation technique, and aftercare are refined, TENs may prove to be the ideal implant to stabilize many pediatric femur fractures, avoiding the prolonged immobilization and complications of traction and spica casting...
- Use of flexible intramedullary nail fixation in treating femur fractures in childrenMichael Khazzam
Department of Orthopaedics, University of Missouri, Columbia, Missouri, USA
Am J Orthop (Belle Mead NJ) 38:E49-55. 2009..7%. These results demonstrate that use of flexible intramedullary nails in the treatment of femoral shaft fractures in children is successful regardless of patient age, fracture location, or fracture pattern...
- Refracture following plate removal in supracondylar-intercondylar femur fracturesBrian L Davison
Grant Medical Center, Columbus, Ohio, USA
Orthopedics 26:157-9. 2003..All refractures occurred during normal functional activities. Patients who request hardware removal following union of a distal femur fracture treated with open reduction and plating should be informed of the possibility of refracture...
- Incidence and demography of femur fractures with and without atypical featuresAdrianne C Feldstein
Kaiser Permanente Center for Health Research, Portland, OR 97227 1110, USA
J Bone Miner Res 27:977-86. 2012..5 years. Patients with only AFMs appear to be different from those with AFMms; it may be that only the latter group is atypical. There appear to be multiple associated risk factors for AFMm fractures...
- Comparison of mechanical rigidity between plate augmentation leaving the nail in situ and interlocking nail using cadaveric fracture model of the femurKyungho Park
Department of Orthopaedics, Kwangju Christian Hospital, Gwangju, Korea
Int Orthop 35:581-5. 2011..0001). We found a 2.6-fold increase in bending stiffness and a 3.3-fold increase in torsional stiffness in plate augmentation leaving a nail in situ compared to interlocking nailing only in the distal third fracture of femur...
- Gender affects macrophage cytokine and prostaglandin E2 production and PGE2 receptor expression after traumaPhilip P Stapleton
Weill Medical College of Cornell University, Department of Surgery, New York, New York, USA
J Surg Res 122:1-7. 2004..This study determined prostaglandin receptor subtype (EP1-EP4) expression following injury and determined whether gender differences influence EP receptor expression...
- Distal femoral fixation: a biomechanical comparison of trigen retrograde intramedullary (i.m.) nail, dynamic condylar screw (DCS), and locking compression plate (LCP) condylar plateJake P Heiney
Department of Orthopaedic Surgery, ProMedica Health System, Toledo, Ohio, USA
J Trauma 66:443-9. 2009..The purpose of this study was to establish if there are biomechanical differences between implants in stiffness of construct, microdisplacement, and fatigue failure in a supracondylar femoral fracture model...
- Changes in the stiffness, strength, and toughness of human cortical bone with ageP Zioupos
Department of Biology, University of York, York, UK
Bone 22:57-66. 1998..The macrocrack was preceded by less damage, and once created needed less energy to drive through the tissue (Wf)...
- The value of a prognostic scoring system in the rehabilitation of elderly patients with proximal femoral fracturesM A Hashmi
Freeman Hospital, Newcastle upon Tyne, UK
Int J Clin Pract 58:2-5. 2004....
- Retrograde intramedullary nailing in distal femoral fractures--results in a series of 46 consecutive operationsLauri Handolin
Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Topeliuksenkatu 5, Helsinki 00260, Finland
Injury 35:517-22. 2004We present a series of 44 consecutive patients with 46 distal femoral fractures, who were treated with a retrograde intramedullary nail (Distal Femoral Nail (DFN))...
- Locking plates for distal femur fractures: is there a problem with fracture healing?Christopher E Henderson
Orthopaedic Surgery, University of Iowa Hospital and Clinics, Iowa City, IA, USA
J Orthop Trauma 25:S8-14. 2011..This article reviews the literature on distal femur fractures treated with locking plates to determine the reported rate of healing difficulties...
- Reverse LISS plates for unstable proximal femoral fracturesChing Hou Ma
Department of Orthopaedics, E Da Hospital I Shou University, No 1, E Da Road, Jiau Shu Tsuen, Yan Chau Shiang, Kaohsiung 824, Taiwan
Injury 41:827-33. 2010The best treatment for unstable proximal femoral fractures is controversial...
- The outcome of surgically treated femur fractures associated with long-term bisphosphonate useYoram A Weil
Department of Orthopaedics, Hadassah Hebrew University Hospital, Jerusalem, Israel
J Trauma 71:186-90. 2011..The aim of this study was to describe the outcome of surgically treated femur fractures associated with prolonged BP use...
- Proximal femoral nail - an analysis of 100 cases of proximal femoral fractures with an average follow up of 1 yearW M Gadegone
Department of Orthopaedic and Traumatology, Chandrapur Multispeciality Hospital, Mul Road, Chandrapur 442401, India
Int Orthop 31:403-8. 2007..Osteosynthesis with the PFN offers the advantages of high rotational stability of the head-neck fragment, an unreamed implantation technique and the possibility of static or dynamic distal locking...
- Stress fracture in military recruits: gender differences in muscle and bone susceptibility factorsT J Beck
Department of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD 21287 0849, USA
Bone 27:437-44. 2000..07). Unlike the bone geometry differences, thigh muscle cross-sectional areas were virtually identical to those of the men, suggesting that the muscles of the women were not relatively weaker...
- Retrograde intramedullary nailing for periprosthetic supracondylar fractures of the femur after total knee arthroplastyHyuk Soo Han
Department of Orthopaedic Surgery, Seoul National University Boramae Medical Center, Seoul, Korea
Clin Orthop Surg 1:201-6. 2009..This study evaluated the efficacy of retrograde intramedullary nailing for the treatment of periprosthetic supracondylar fractures of the femur using the clinical outcomes...
- Austin-Moore hemiarthroplasty for failed osteosynthesis of intracapsular proximal femoral fracturesC Roberts
Department of Orthopaedics, Addenbrooke s Hospital, Hills Road, Peterborough, Cambs CB2 2QQ, UK
Injury 33:423-6. 2002..Austin-Moore hemiarthroplasties used as a revision procedure for failed osteosynthesis of intracapsular femoral fractures. This group was compared with 730 patients in whom an uncemented Austin-Moore prosthesis had been used as ..
- Pathophysiology of atypical femoral fractures and osteonecrosis of the jawJ Compston
Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK
Osteoporos Int 22:2951-61. 2011In recent years, atypical femoral fractures and osteonecrosis of the jaw have emerged as potential complications of long-term bisphosphonate therapy; osteonecrosis of the jaw has also been reported in patients receiving high doses of ..
- [Animal models for bone and joint disease. Animal fracture model and fracture healing process]Tasuku Mashiba
Department of Orthopedic Surgery, Kagawa University Faculty of Medicine
Clin Calcium 21:235-41. 2011..Fracture healing is completed by not only bone union of fracture site but restoration of original bony shape and bone quality due to progression of callus remodeling...
- Elastic stable intramedullary nailing in pediatric femur and lower leg shaft fractures: intraoperative radiation loadRalf Kraus
Department of Trauma Surgery, University Hospital Giessen and Marburg, Giessen, Germany
J Pediatr Orthop 28:14-6. 2008..Literature concerning intraoperative radiation load in ESIN is rare, results having a wide range from less than 1 minute to more than 15 minutes...
- Surgical treatment of femoral fractures in obese children: does excessive body weight increase the rate of complications?Arabella I Leet
Department of Orthopaedic Surgery, Johns Hopkins University, 601 North Caroline Street, Room 5255, Baltimore, MD 21287 0882, USA
J Bone Joint Surg Am 87:2609-13. 2005..In light of the increasing rate of obesity among children in the United States, this study examines whether obese children have an increased rate of complications following surgical treatment of femoral shaft fractures...
- Complications of titanium elastic nails for pediatric femoral shaft fracturesScott J Luhmann
Department of Orthopaedic Surgery, Washington University School of Medicine and St Louis Children s Hospital, Missouri 63110, USA
J Pediatr Orthop 23:443-7. 2003..Technical pitfalls exist with this implant and can be minimized by leaving less than 2.5 cm of nail out of the femur and by using the largest nail sizes possible...
- Intramedullary nailing of femoral fractures in adolescentsN Momberger
Department of Orthopedics, University of Utah, Salt Lake City, USA
J Pediatr Orthop 20:482-4. 2000..Intramedullary nailing through a trochanteric starting point is a safe, effective method for treating femur fractures in this adolescent age group...
- Effects of calcium supplements on fracture healing in a rat osteoporotic modelAhmad Nazrun Shuid
Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abd Aziz, 50300 KL, Malaysia
J Orthop Res 28:1651-6. 2010..Therefore, calcium supplements may appear to improve fracture healing of osteoporotic bone but failed to improve strength...
- Ender nail fixation of pediatric femur fractures: a biomechanical analysisS S Lee
Children's Hospital and Health Center and University of California at San Diego, San Diego, California 92123-4293
J Pediatr Orthop 21:442-5. 2001..These data suggest that length and rotational control of comminuted midshaft femur fractures with two divergent Ender nails may be sufficient for early mobilization...
- Biomechanical comparison of flexible stainless steel and titanium nails with external fixation using a femur fracture modelUsha S Mani
Department of Orthopedics Research Laboratory, UMDNJ New Jersey Medical School, Newark, NJ 07103, USA
J Pediatr Orthop 26:182-7. 2006..No significant benefit was demonstrated with double stacking of external fixators. These findings may help guide clinicians choose the optimal fixation method for treatment of pediatric femoral shaft fractures...
- Titanium elastic nailing of fractures of the femur in children. Predictors of complications and poor outcomeL A Moroz
Department of Orthopaedic Surgery, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104 4399, USA
J Bone Joint Surg Br 88:1361-6. 2006..003). A poor outcome was five times more likely in children who weighed more than 49 kg...
- Resuscitation before stabilization of femoral fractures limits acute respiratory distress syndrome in patients with multiple traumatic injuries despite low use of damage control orthopedicsRobert V O'Toole
Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
J Trauma 67:1013-21. 2009..Our approach to treating femoral fractures in patients with multiple traumatic injuries is to perform reamed nailing after adequate resuscitation has ..
- Fragility fractures of the hip and femur: incidence and patient characteristicsJ W Nieves
Department of Epidemiology, Columbia University, New York, NY, USA
Osteoporos Int 21:399-408. 2010Using national discharge and medical claims data, we studied the epidemiology of femoral fractures from 1996 to 2006...
- Stimulation of the local femoral inflammatory response to fracture and intramedullary reaming: a preliminary study of the source of the second hit phenomenonJ R Morley
Academic Department of Orthopaedic and Trauma Surgery, Leeds University, The General Infirmary at Leeds, Clarendon Wing, Great George Street, Leeds LS1 3EX, UK
J Bone Joint Surg Br 90:393-9. 2008..In patients who underwent intramedullary reaming of the femoral canal a further significant local release of IL-6 was demonstrated, providing evidence that intramedullary reaming can cause a significant local inflammatory reaction...
- Compression plating of pediatric femoral shaft fracturesMichelle S Caird
Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, Michigan 48109, USA
J Pediatr Orthop 23:448-52. 2003..Compression plate fixation is a safe and effective treatment in children with both isolated femoral shaft fractures and those associated with multiple injuries...
- Proximal femoral radiographic changes after lateral transtrochanteric intramedullary nail placement in childrenJ Eric Gordon
Washington University School of Medicine, St Louis Shriners Hospital for Children, Missouri, USA
J Bone Joint Surg Am 85:1295-301. 2003..The mean age of the patients at the time of the index procedure was ten years and six months...
- Effect of 1,25-dihydroxy vitamin D3 on fracture healing and bone remodeling in ovariectomized rat femoraLingjie Fu
Department of Orthopaedic Surgery, Ninth People s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, PR China
Bone 44:893-8. 2009..In conclusion, 1,25(OH)(2)D(3) could promote fracture healing by improving the histomorphometric parameters, mechanical strength and tendency to increase transformation of woven bone into lamellar bone in an ovariectomized rat model...
- Systemic inflammatory response after extremity or truncal fracture operationsHans Christoph Pape
Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Trauma 65:1379-84. 2008..The purpose of this study was to assess proinflammatory markers in blunt trauma patients regarding the relationship of these and blood loss and duration of surgery in different fracture locations...
- Case report : femoral shaft fracture resulting from femoral tracker placement in navigated TKAPeter Bonutti
St Anthony s Hospital, Effingham, IL, USA
Clin Orthop Relat Res 466:1499-502. 2008..We report two patients with displaced femoral fractures at optical tracker pin placement sites created for routine performance of navigated TKA...
- Management of pediatric femoral shaft fracturesJohn M Flynn
Division of Orthopaedic Surgery, The Children s Hospital of Philadelphia, 2nd Floor Wood Building, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
J Am Acad Orthop Surg 12:347-59. 2004..Risks of surgical management include refracture after external fixator or plate removal, osteonecrosis after rigid antegrade intramedullary nail fixation, and soft-tissue irritation caused by the ends of flexible nails...
- Antipsychotic use and the risk of hip/femur fracture: a population-based case-control studyS Pouwels
Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
Osteoporos Int 20:1499-506. 2009..Furthermore, no evidence for a dose effect was found...
- The science of fracture healingThomas A Einhorn
Boston University Medical Center, Department of Orthopaedic Surgery, Boston, MA 02118, USA
J Orthop Trauma 19:S4-6. 2005..This article summarizes the series of cellular and molecular events that take place in the process of endochondral fracture healing, based on observations obtained from an animal model of a femoral fracture...
- The risk of child abuse in infants and toddlers with lower extremity injuriesCarla Coffey
The Trauma Program, Children s Hospital, Columbus, OH 43205, USA
J Pediatr Surg 40:120-3. 2005..The aim of this study was to assess the risk of child abuse in children younger than 18 months admitted to a pediatric trauma service with lower extremity injuries...
- A biomechanical study on flexible intramedullary nails used to treat pediatric femoral fracturesJason K Green
Department of Orthopedic Surgery, SUNY Upstate Medical University, 3214 Institute for Human Performance, 505 Irving Avenue Syracuse, NY 13210, USA
J Orthop Res 23:1315-20. 2005Flexible intramedullary nails have been indicated to treat femoral fractures in pediatric patients...
- Use of anti-depressants and the risk of fracture of the hip or femurM W M van den Brand
Department of Geriatric Medicine, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
Osteoporos Int 20:1705-13. 2009..This should be considered when prescribing anti-depressants to patients...
- Features of femoral fractures in nonaccidental injuryC Rex
Manchester Children s Hospitals, University of Manchester, United Kingdom
J Pediatr Orthop 20:411-3. 2000..It is important medicolegally to establish a diagnosis of child abuse. Fourteen femoral fractures from definite nonaccidental injury were analysed and compared with 33 femoral fractures caused by definite ..
- Computer navigation allows for accurate reduction of femoral fracturesYoram A Weil
Orthopaedic Trauma Service, Hospital for Special Surgery, New York, NY, USA
Clin Orthop Relat Res 460:185-91. 2007Femoral nailing for reduction and stabilization of femoral fractures is a common orthopaedic procedure. However, angular and rotational malalignment is not an infrequent result, and extensive use of fluoroscopy is commonly involved...
- Intermittent PTH(1-34) does not increase union rates in open rat femoral fractures and exhibits attenuated anabolic effects compared to closed fracturesMagnus Tagil
Orthopaedic Research and Biotechnology, The Children s Hospital, Westmead, Australia
Bone 46:852-9. 2010..In the open fractures that did unite, a muted response to PTH was seen compared to closed fractures. Further research is required to determine if PTH((1-34)) is an appropriate anabolic treatment for open fractures...
- Child abuse in infants with proximal physeal injuries of the femurJoshua C W Jones
General Pediatric Division, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA
Pediatr Emerg Care 20:157-61. 2004..Fractures of the proximal femoral physis in abused infants have been less emphasized. Our report seeks to highlight this infrequent but clinically important inflicted injury...
- The threshold force required for femoral impaction grafting in revision hip surgeryOlivia M Flannery
Trinity Centre for Bioengineering, School of Engineering, Trinity College, Dublin, Ireland
Acta Orthop 81:303-7. 2010..Femoral impaction grafting requires vigorous impaction to obtain adequate stability without risk of fracture, but the force of impaction has not been determined. We determined this threshold force in a preliminary study using animal femurs...
- Biomechanical analysis of antegrade and retrograde flexible intramedullary nail fixation of pediatric femoral fractures using a synthetic bone modelKevin B Fricka
Department of Orthopaedic Surgery, Children s Hospital, San Diego, California, USA
J Pediatr Orthop 24:167-71. 2004Biomechanical testing was performed to evaluate the stability of simulated transverse and comminuted femoral fractures after retrograde and antegrade flexible titanium intramedullary nail fixation...
- Evolution of minimally invasive plate osteosynthesis (MIPO) in the femurC Krettek
Trauma Department, Hannover Medical School, Germany
Injury 32:SC14-23. 2001Problems with conventional open reduction and internal plate fixation of distal femoral fractures are well established. These problems have been associated with extensile exposures of the fracture site...
- Intramedullary nailing of femoral shaft fractures: current conceptsWilliam M Ricci
Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
J Am Acad Orthop Surg 17:296-305. 2009..This method yields high union rates and low complication rates when vigilance is maintained during preoperative planning, the surgical procedure, and the postoperative period...
- VEGF serum concentrations in patients with long bone fractures: a comparison between impaired and normal fracture healingKambiz Sarahrudi
Department of Traumatology, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
J Orthop Res 27:1293-7. 2009....
- A novel, non-prostanoid EP2 receptor-selective prostaglandin E2 agonist stimulates local bone formation and enhances fracture healingMei Li
Department of Cardiovascular and Metabolic Diseases, Pfizer Global Research and Development, Groton Laboratories, Groton, Connecticut 06340, USA
J Bone Miner Res 18:2033-42. 2003..CP-533,536, a newly discovered, non-prostanoid EP2 receptor-selective PGE2 agonist, stimulates local bone formation and enhances fracture healing in rat models...
- Biomechanical evaluation of the less invasive stabilization system, angled blade plate, and retrograde intramedullary nail for the internal fixation of distal femur fracturesMichael Zlowodzki
Department of Orthopedic Surgery, University of Minnesota, Regions Hospital, St Paul, MN, USA
J Orthop Trauma 18:494-502. 2004..To evaluate the stability of the retrograde intramedullary nail (IMN), angled blade plate (ABP), and a locked internal fixator (Less Invasive Stabilization System [LISS], Synthes, Paoli, PA) for internal fixation of distal femur fractures...
- Microdamage of human cortical bone: incidence and morphology in long bonesT L Norman
Department of Mechanical and Aerospace Engineering, West Virginia University, Morgantown 26506 9196, USA
Bone 20:375-9. 1997..It was also found that microdamage increased with age, was significantly greater in females than males, and was significantly greater in the proximal femur than the midshaft of the tibia...
- Modeling fracture prediction in spinal cord injury and diseaseLaura D Carbone; Fiscal Year: 2013..side effects from pharmacological therapies for osteoporosis including osteonecrosis of the jaw and atypical femoral fractures have been reported...
- TNSALP Mutations in Atypical Femoral Fractures with Long-Term Bisphosphonate UseSTEVEN R MUMM; Fiscal Year: 2013..for Bone and Mineral Research to investigate the association of atypical subtrochanteric and diaphyseal femoral fractures (ASFFs) with the long-term use of bisphosphonates for osteoporosis...
- IBMS Sun Valley Workshop on Musculoskeletal BiologyDavid B Burr; Fiscal Year: 2013..both themes by addressing osteocyte signaling in the repair of stress fractures, relating this to atypical femoral fractures. Many opportunities are provided for junior investigators to interact with more senior investigators...
- Pathogenesis of Atypical Femur Fractures on Long Term Bisphosphonate TherapyD Sudhaker Rao; Fiscal Year: 2013..However, since 2005 there have been many reports of atypical femoral fractures (AFF) in patients on prolonged BP therapy...
- Unintended muscle activity influences on post-stroke locomotionCITLALI LOPEZ ORTIZ; Fiscal Year: 2007..body during locomotion and place individuals with post-stroke hemiplegia at high risk for frequent falls and femoral fractures. Thus, it is necessary to study muscle coordination patterns to identify the underlying causative mechanisms ..
- Molecular Mechanisms of Skeletal RepairThomas Einhorn; Fiscal Year: 2008..Successful establishment and implementation of this program will greatly enhance the coordinated activities of this team of investigators and lead to important new results and directions for skeletal healing research. ..
- MUSCULOSKELETAL TRAINING GRANTDavid Burr; Fiscal Year: 2006..Two presentations were nominated for Young Investigator Awards by the ASBMR and the ORS. ..
- Sun Valley Workshop on Skeletal BiologyDavid Burr; Fiscal Year: 2004..An Advisory Panel is formed of session chairs. There are plans to advertise and distribute a summary of the workshop, partly using Web-based resources. ..
- Sun Valley Workshop on Skeletal BiologyDavid Burr; Fiscal Year: 2006..There are plans to advertise and distribute a summary of the workshop, partly using Web-based resources. [unreadable] [unreadable] [unreadable] [unreadable]..
- Sun Valley Workshop on Skeletal BiologyDavid Burr; Fiscal Year: 2007..There are plans to advertise and distribute a summary of the workshop, partly using Web-based resources. [unreadable] [unreadable] [unreadable] [unreadable]..
- Sun Valley Workshop on Skeletal BiologyDavid Burr; Fiscal Year: 2005..An Advisory Panel is formed of session chairs. There are plans to advertise and distribute a summary of the workshop, partly using Web-based resources. ..
- Sun Valley Workshop on Skeletal BiologyDavid Burr; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- TWO X-LINKED GENES THAT REGULATE MINERAL HOMEOSTASISMichael Whyte; Fiscal Year: 2002....
- Genes Controlling the Renal Handling of PhosphateRalph Meyer; Fiscal Year: 2004..Such intervention may improve the skeletal symptoms of patients with hypophosphatemic bone disease and improve their quality of life. ..
- Hip Fracture Evaluation Alternatives of Total Hip vs Hemi-arthroplasty (HEALTH)Thomas Einhorn; Fiscal Year: 2009..Potential Impact: This trial will not only change current orthopaedic practice, but will set a benchmark for the conduct of future orthopaedic trials. ..
- MECHANOTRANSDUCTION IN BONEDavid Burr; Fiscal Year: 2003..Data generated by this Program are intended to define some mechanisms by which fluid forces can regulate gene expression, and will attempt to validate these mechanisms by in vivo studies. ..
- Forging Implementation of Cancer Screening Reminder Systems (FICSRS)Adrianne Feldstein; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- EFFECTS OF AGE ON SIGNALING IN HUMAN OSTEOBLASTOGENESISJulie Glowacki; Fiscal Year: 2010....
- IDIOPATHIC OSTEOPOROSIS IN PREMENOPAUSAL WOMENElizabeth Shane; Fiscal Year: 2009..The results of these studies will have important therapeutic implications for the diagnosis and management of this disorder. ..
- A Virtual Reality Based Joint Injection Simulator Phase IIKarl Reinig; Fiscal Year: 2007..The system is designed to reduce the trainee's dependence on patients as training devices. [unreadable] [unreadable] [unreadable]..
- MAP KINASE REGULATION OF OSTEOBLAST FUNCTIONRenny Franceschi; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- TISSUE ENGINEERING OF GROWING JOINTSJulie Glowacki; Fiscal Year: 2002..In vivo fate of engineered joints will be assessed in our model of murine joint transplantation and will be further verified in the pig. ..
- A VIRTUAL ENVIRONMENT FOR ARTHROSCOPY SIMULATIONKarl Reinig; Fiscal Year: 2003..It will also provide a platform for orthopedic tool and device makers to introduce and to train doctors on their new developments. ..
- BONE SIALOPROTEIN: EXPRESSION & ROLE IN MINERALIZATIONRenny Franceschi; Fiscal Year: 2004..Such knowledge is essential for designing new strategies for bone regeneration to treat trauma and pathological conditions such as osteoporosis and periodontal disease. ..
- Prevention of Osteoporosis after TransplantationElizabeth Shane; Fiscal Year: 2002..We are now applying for 3 years of support to complete 12 months of observation on those subjects enrolled after March, 2001 and to complete an additional 24 months of follow-up on enrolled participants. ..
- A Whole Body, Multi-Purpose, Ultrasound SimulatorKarl Reinig; Fiscal Year: 2005....
- Bioreactor Expansion and Transplantation of ES Cell Derived Osteoblasts and ChondJohn Matyas; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- TISSUE STRESS VARIABILITY AND STRENGTH IN VERTEBRAL BONEYener Yeni; Fiscal Year: 2006..abstract_text> ..
- Weight in Secondary Prevention (WISP)Adrianne Feldstein; Fiscal Year: 2006..Understanding which patients will need the most support to manage weight will allow us to design the most cost-effective future programs. ..
- Pregnancy Outcomes in Polycystic Ovary SyndromeJoan Lo; Fiscal Year: 2009....
- BISPHOSPHONATE BONE QUALITY IN WOMEN WITH BREAST CANCERSusan Ott; Fiscal Year: 2009..Results of the study will provide valuable information about skeletal effects of high-dose bisphosphonates in humans. ..
- Rabbit Model for In Vivo Monitoring of Bone StructureMichael Voor; Fiscal Year: 2003..It will give investigators the opportunity to watch the specific trabecular surfaces that are affected by various treatments and to observe when these effects occur. ..
- Effect of Aging & Vitamin D Status on OsteoblastogenesisJulie Glowacki; Fiscal Year: 2008..abstract_text> ..
- Fatigue Crack Morphology in Cemented HipsAmos Race; Fiscal Year: 2002....
- Spectroscopic X-ray Bone DensitometryThomas Beck; Fiscal Year: 2008..The disease is characterized by low bone mass, leading to enhanced bone fragility and a significant increase in the risk of fractures, which is typically diagnosed by bone densitometer [1,2]. [unreadable] [unreadable] [unreadable]..
- Effect of Femoral Stem Design om Cement Mantle FailureAmos Race; Fiscal Year: 2006..Should these aims be met, the proposed model will be of great use in pre-clinical testing of novel cemented stem designs. ..
- Clinical Decision Rule to Identify Children with Intra-Abdominal InjuriesJames Holmes; Fiscal Year: 2008..unreadable]..
- Sphingosine 1-phosphate and PMN Ca2+ entry in traumaCarl Hauser; Fiscal Year: 2009..Determine the side effects and complications of SOCE inhibition after shock. 3. Determine the effects of injury on intracellular S1P/SOCE signaling 4. Determine the mechanisms by which circulating S1P activates PMN after trauma. ..
- Induced hypothermic arrest in traumatic shockHasan Alam; Fiscal Year: 2005..Sub aim 2: Develop and test methods and techniques that can facilitate the induction of hypothermic arrest in the setting of traumatic shock. ..