femoral fractures

Summary

Summary: Fractures of the femur.

Top Publications

  1. ncbi Treatment of acute distal femur fractures above a total knee arthroplasty: systematic review of 415 cases (1981-2006)
    Diego A Herrera
    Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, USA
    Acta Orthop 79:22-7. 2008
  2. ncbi Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for Bone and Mineral Research
    Elizabeth Shane
    Columbia University, College of Physicians and Surgeons, PH 8 West 864, 630 West 168th Street, New York, NY 10032, USA
    J Bone Miner Res 25:2267-94. 2010
  3. ncbi Bilateral low-energy simultaneous or sequential femoral fractures in patients on long-term alendronate therapy
    Craig M Capeci
    Department of Orthopaedic Surgery, New York University Hospital for Joint Diseases, 301 East 17th Street, Suite 1401, New York, NY 10003, USA
    J Bone Joint Surg Am 91:2556-61. 2009
  4. ncbi Low-energy femoral shaft fractures associated with alendronate use
    Andrew S Neviaser
    Hospital for Special Surgery, New York, NY, USA
    J Orthop Trauma 22:346-50. 2008
  5. ncbi Low-energy femoral fractures associated with the long-term use of bisphosphonates: a case series from a Swiss university hospital
    Kuntheavy Ing-Lorenzini
    Division of Clinical Pharmacology and Toxicology, Regional Pharmacovigilance Centre, University Hospitals of Geneva, Geneva, Switzerland
    Drug Saf 32:775-85. 2009
  6. ncbi Atypical femoral fractures are a separate entity, characterized by highly specific radiographic features. A comparison of 59 cases and 218 controls
    Jörg Schilcher
    Orthopedics, Department of Clinical and Experimental Medicine, Faculty of Health Science, Linkoping University, Sweden
    Bone 52:389-92. 2013
  7. ncbi Effect of a statewide fall prevention program on incidence of femoral fractures in residents of long-term care facilities
    Kilian Rapp
    Department of Clinical Gerontology, Robert Bosch Hospital, Stuttgart, Germany
    J Am Geriatr Soc 58:70-5. 2010
  8. ncbi Use of inhaled and oral glucocorticoids, severity of inflammatory disease and risk of hip/femur fracture: a population-based case-control study
    F De Vries
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, The Netherlands
    J Intern Med 261:170-7. 2007
  9. ncbi Bisphosphonate use and atypical fractures of the femoral shaft
    Jörg Schilcher
    Department of Experimental and Clinical Medicine, Faculty of Health Science, Linkoping University, Linkoping, Sweden
    N Engl J Med 364:1728-37. 2011
  10. ncbi Locking compression plates for the treatment of periprosthetic femoral fractures around well-fixed total hip and knee implants
    Gavin C A Wood
    Division of Orthopaedic Surgery, Queen s University, Kingston Ontario, Canada
    J Arthroplasty 26:886-92. 2011

Detail Information

Publications310 found, 100 shown here

  1. ncbi Treatment of acute distal femur fractures above a total knee arthroplasty: systematic review of 415 cases (1981-2006)
    Diego A Herrera
    Department of Orthopaedic Surgery, University of Minnesota, Minneapolis, MN, USA
    Acta Orthop 79:22-7. 2008
    ..There is no consensus on the best treatment for periprosthetic supracondylar fracture...
  2. ncbi Atypical subtrochanteric and diaphyseal femoral fractures: report of a task force of the American Society for Bone and Mineral Research
    Elizabeth Shane
    Columbia University, College of Physicians and Surgeons, PH 8 West 864, 630 West 168th Street, New York, NY 10032, USA
    J Bone Miner Res 25:2267-94. 2010
    ..The task force defined major and minor features of complete and incomplete atypical femoral fractures and recommends that all major features, including their location in the subtrochanteric region and femoral ..
  3. ncbi Bilateral low-energy simultaneous or sequential femoral fractures in patients on long-term alendronate therapy
    Craig M Capeci
    Department of Orthopaedic Surgery, New York University Hospital for Joint Diseases, 301 East 17th Street, Suite 1401, New York, NY 10003, USA
    J Bone Joint Surg Am 91:2556-61. 2009
    ..have associated long-term alendronate therapy with unilateral low-energy subtrochanteric and diaphyseal femoral fractures in a small number of patients...
  4. ncbi Low-energy femoral shaft fractures associated with alendronate use
    Andrew S Neviaser
    Hospital for Special Surgery, New York, NY, USA
    J Orthop Trauma 22:346-50. 2008
    ..The purpose of this study is to demonstrate an association between alendronate use and a specific pattern of low-energy femoral shaft fracture...
  5. ncbi Low-energy femoral fractures associated with the long-term use of bisphosphonates: a case series from a Swiss university hospital
    Kuntheavy Ing-Lorenzini
    Division of Clinical Pharmacology and Toxicology, Regional Pharmacovigilance Centre, University Hospitals of Geneva, Geneva, Switzerland
    Drug Saf 32:775-85. 2009
    ..Bisphosphonates are effective and well tolerated anti-resorptive drugs used for the treatment of osteoporosis. However, some concerns about their potential long-term negative effects are emerging...
  6. ncbi Atypical femoral fractures are a separate entity, characterized by highly specific radiographic features. A comparison of 59 cases and 218 controls
    Jörg Schilcher
    Orthopedics, Department of Clinical and Experimental Medicine, Faculty of Health Science, Linkoping University, Sweden
    Bone 52:389-92. 2013
    Estimations of the risk of bisphosphonate associated atypical femoral fractures vary between different population-based studies, from considerable to neglectable...
  7. ncbi Effect of a statewide fall prevention program on incidence of femoral fractures in residents of long-term care facilities
    Kilian Rapp
    Department of Clinical Gerontology, Robert Bosch Hospital, Stuttgart, Germany
    J Am Geriatr Soc 58:70-5. 2010
    To evaluate the effect of a statewide dissemination of a modified evidence-based fall prevention program on incidence of femoral fractures in nursing homes.
  8. ncbi Use of inhaled and oral glucocorticoids, severity of inflammatory disease and risk of hip/femur fracture: a population-based case-control study
    F De Vries
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, The Netherlands
    J Intern Med 261:170-7. 2007
    ..Patients using higher dosages of inhaled or oral glucocorticoids (GCs) have an increased risk of hip/femur fractures. The role of the underlying disease in the aetiology of this increased risk has not been widely studied...
  9. ncbi Bisphosphonate use and atypical fractures of the femoral shaft
    Jörg Schilcher
    Department of Experimental and Clinical Medicine, Faculty of Health Science, Linkoping University, Linkoping, Sweden
    N Engl J Med 364:1728-37. 2011
    ..Studies show conflicting results regarding the possible excess risk of atypical fractures of the femoral shaft associated with bisphosphonate use...
  10. ncbi Locking compression plates for the treatment of periprosthetic femoral fractures around well-fixed total hip and knee implants
    Gavin C A Wood
    Division of Orthopaedic Surgery, Queen s University, Kingston Ontario, Canada
    J Arthroplasty 26:886-92. 2011
    ..few published studies examining the use of locking compression plates for the treatment of periprosthetic femoral fractures. Fifteen total hip or knee arthroplasty patients with 16 Vancouver type B1 and C fractures with an average ..
  11. ncbi Increasing occurrence of atypical femoral fractures associated with bisphosphonate use
    Raphael P H Meier
    Department of Surgery, University Hospitals of Geneva and Faculty of Medicine, Geneva, Switzerland
    Arch Intern Med 172:930-6. 2012
    Current evidence suggests that there is an association between bisphosphonate therapy and atypical femoral fractures, but the extent of this risk remains unclear.
  12. ncbi Distal femoral fracture fixation utilizing the Less Invasive Stabilization System (L.I.S.S.): the technique and early results
    P J Kregor
    Department of Orthopedic Surgery, University of Mississippi Medical Center, Jackson 39216, USA
    Injury 32:SC32-47. 2001
    The treatment of supracondylar femoral fractures in the past three decades has evolved from non-operative to operative treatment...
  13. ncbi Radiographic and functional results of osteosynthesis using the proximal femoral nail antirotation (PFNA) in the treatment of unstable intertrochanteric femoral fractures
    Suner Sahin
    Department of Orthopedics and Traumatology, Sisli Etfal Training and Research Hospital, Istanbul
    Acta Orthop Traumatol Turc 44:127-34. 2010
    We evaluated the radiographic and functional results of the proximal femoral nail antirotation (PFNA) system in patients with unstable intertrochanteric femoral fractures.
  14. ncbi Mid-term outcomes after intramedullary fixation of peritrochanteric femoral fractures using the new proximal femoral nail antirotation (PFNA)
    Yake Liu
    Department of Orthopaedics, The Affiliated Hospital of Nantong University, 20 Xisi Road, Nantong City, Jiangsu Province 226001, PR China
    Injury 41:810-7. 2010
    Controversy persists concerning the preferred treatment of peritrochanteric femoral fractures. The purpose of the present study was to evaluate the mid-term outcomes of the newly developed implants - proximal femoral nail antirotation (..
  15. ncbi Importance of screw position in intertrochanteric femoral fractures treated by dynamic hip screw
    M Guven
    The Hospital of University of Abant Izzet Baysal, Department of Orthopaedics and Traumatology, 14280 Bolu, Turkey
    Orthop Traumatol Surg Res 96:21-7. 2010
    ..The aim of this retrospective study was to evaluate the position of the screw in the femoral head and its effect on cut-out failure especially in patients with inconvenient tip-apex distance...
  16. ncbi The role and efficacy of retrograding nailing for the treatment of diaphyseal and distal femoral fractures: a systematic review of the literature
    G Papadokostakis
    Department of Trauma, St James s University Hospital, Beckett Street, Leeds LS9 7TF, UK
    Injury 36:813-22. 2005
    ..8 years) who sustained 963 distal and diaphyseal femoral fractures. The overall mortality rate was 5.3%. The incidence of infection was 1...
  17. ncbi The effect of time to definitive treatment on the rate of nonunion and infection in open fractures
    Brian J Harley
    Division of Orthopaedic Surgery, Department of Surgery, University of Alberta Hospital, Edmonton, Alberta, Canada
    J Orthop Trauma 16:484-90. 2002
    ..To determine the association of other clinical determinants with these same adverse events...
  18. pmc Incidence of stress fractures of the femoral shaft in women treated with bisphosphonate
    Jörg Schilcher
    Department of Orthopedics, AIM IKE, Faculty of Health Science, Linkoping University, Linkoping, Sweden
    Acta Orthop 80:413-5. 2009
    ..Recent case reports have identified an association between long-term bisphosphonate treatment and stress fractures of the femoral shaft. The risk of such fractures in bisphosphonate users has not been determined...
  19. ncbi Complications of pediatric femur fractures treated with titanium elastic nails: a comparison of fracture types
    Ernest L Sink
    Department of Orthopaedics, University of Colorado Health Science Center, School of Medicine, Denver, CO 80218, USA
    J Pediatr Orthop 25:577-80. 2005
    ..The authors conclude that in patients with "length-unstable" femur fractures, consideration should be given to methods of treatment other than titanium flexible intramedullary nails...
  20. ncbi Correlation between IL-6 levels and the systemic inflammatory response score: can an IL-6 cutoff predict a SIRS state?
    Peter V Giannoudis
    Academic Department of Trauma Surgery, Leeds University, Leeds, United Kingdom
    J Trauma 65:646-52. 2008
    ..The aim of this study was to investigate, in a group of adult trauma patients, the relationship between the interleukin-6 (IL-6) concentration, the systemic inflammatory response score (SIRS) and outcome...
  21. ncbi Use of flexible intramedullary nails in pediatric femur fractures
    Christine Ann Ho
    Children s Orthopaedic Center, Children s Hospital Los Angeles, CA, USA
    J Pediatr Orthop 26:497-504. 2006
    ..Although the end results are favorable, complications are relatively frequent, particularly in older children...
  22. pmc Are short femoral nails superior to the sliding hip screw? A meta-analysis of 24 studies involving 3,279 fractures
    Henry Wynn Jones
    Department of Orthopaedics, Bedford Hospital, Kempston Road, MK42 9DJ, Bedford, UK
    Int Orthop 30:69-78. 2006
    ..the sliding hip screw (SHS) and intramedullary nails (IMN) in stable and unstable extracapsular proximal femoral fractures. All randomised controlled studies comparing IMNs with a SHS were considered for inclusion...
  23. ncbi A comparison of the long gamma nail with the sliding hip screw for the treatment of AO/OTA 31-A2 fractures of the proximal part of the femur: a prospective randomized trial
    Tristan M Barton
    Department of Trauma and Orthopaedics, Frenchay Hospital, Frenchay Park Road, Frenchay, Bristol BS6 1LE, United Kingdom
    J Bone Joint Surg Am 92:792-8. 2010
    ..A prospective, randomized, controlled trial was performed to compare the outcome of treatment of these unstable fractures of the proximal part of the femur with either a sliding hip screw or a long gamma nail...
  24. pmc Impact of the method of initial stabilization for femoral shaft fractures in patients with multiple injuries at risk for complications (borderline patients)
    Hans Christoph Pape
    Division of Trauma, Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
    Ann Surg 246:491-9; discussion 499-501. 2007
    ....
  25. ncbi Association of low-energy femoral fractures with prolonged bisphosphonate use: a case control study
    B A Lenart
    Hospital for Special Surgery, New York, NY 10021, USA
    Osteoporos Int 20:1353-62. 2009
    ..Further studies are warranted...
  26. ncbi Comparison of titanium elastic nails with traction and a spica cast to treat femoral fractures in children
    John M Flynn
    Division of Orthopaedics, Children s Hospital of Philadelphia, 34th and Civic Center Boulevard, Philadelphia, PA 19104 4399, USA
    J Bone Joint Surg Am 86:770-7. 2004
    Titanium elastic nails are commonly used to stabilize femoral fractures in school-aged children, but there have been few studies assessing the risks and benefits of this procedure compared with those of traditional traction and ..
  27. ncbi Evolution of the internal fixation of long bone fractures. The scientific basis of biological internal fixation: choosing a new balance between stability and biology
    Stephan M Perren
    AO Research and Development Institutes, Davos, Switzerland
    J Bone Joint Surg Br 84:1093-110. 2002
    ..The phenomenon of bone loss and stress protection has a biological rather than a mechanical explanation. The same mechanism of necrosis-induced internal remodelling may explain the basic process of direct healing...
  28. ncbi Should bisphosphonates be continued indefinitely? An unusual fracture in a healthy woman on long-term alendronate
    Jennifer P Schneider
    Geriatrics 61:31-3. 2006
  29. pmc Use of beta-blockers and the risk of hip/femur fracture in the United Kingdom and The Netherlands
    F De Vries
    Division of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science, Universiteit Utrecht, Sorbonnelaan 16, 3584 CA Utrecht, The Netherlands
    Calcif Tissue Int 80:69-75. 2007
    ....
  30. ncbi Do sacrificial bonds affect the viscoelastic and fracture properties of bone?
    Yener N Yeni
    Section of Biomechanics, Bone and Joint Center, Department of Orthopaedics and Rehabilitation, Henry Ford Hospital, Detroit, MI 48202, USA
    Clin Orthop Relat Res 443:101-8. 2006
    ..These effects were reversible, consistent with the original proposal. However, these effects may not necessarily indicate an increase in strength or toughness of the tissue at the macro scale...
  31. ncbi Femoral fracture fixation in developing countries: an evaluation of the Surgical Implant Generation Network (SIGN) intramedullary nail
    Patrick Sekimpi
    Department of Orthopaedics, Mulago Hospital, P O Box 7051, Kampala, Uganda
    J Bone Joint Surg Am 93:1811-8. 2011
    The Surgical Implant Generation Network (SIGN) intramedullary nailing system was designed to treat femoral fractures in developing countries where real-time imaging, power equipment, and fracture tables are often not available...
  32. ncbi Atypical subtrochanteric and diaphyseal femoral fractures: second report of a task force of the American Society for Bone and Mineral Research
    Elizabeth Shane
    Author affiliations appear on pp 15 20
    J Bone Miner Res 29:1-23. 2014
    ..When BPs are stopped, risk of an AFF may decline. Lower limb geometry and Asian ethnicity may contribute to the risk of AFFs. There is inconsistent evidence that teriparatide may advance healing of AFFs...
  33. ncbi Locked plating of supracondylar periprosthetic femur fractures
    Thomas M Large
    Department of Orthopaedic Surgery, Carolinas Medical Center, PO Box 32861, Charlotte, North Carolina, USA
    J Arthroplasty 23:115-20. 2008
    ..Locked plating is a reliable treatment for periprosthetic supracondylar femur fractures. We experienced a lower complication, revision, malunion, and nonunion rate with locked plating versus conventional treatment options...
  34. ncbi Locking plate osteosynthesis for Vancouver Type B1 and Type C periprosthetic fractures of femur: a report on 12 patients
    Jagannath Chakravarthy
    South Birmingham Trauma Unit, Selly Oak Hospital, 1071 Bristol Road South, Birmingham, UK
    Injury 38:725-33. 2007
    ..There were no infections. Our experience encourages us that locking plates have a role to play in managing periprosthetic fractures around a stable femoral stem, especially in patients with poor soft tissue and osteoporosis...
  35. pmc Low infection rates after 34,361 intramedullary nail operations in 55 low- and middle-income countries: validation of the Surgical Implant Generation Network (SIGN) online surgical database
    Sven Young
    Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 82:737-43. 2011
    ..Most operations are reported to the SIGN Online Surgical Database (SOSD). Follow-up has been reported to be low, however. We wanted to examine the pattern of follow-up and to assess whether infection rates could be trusted...
  36. ncbi Atypical femoral fractures and bisphosphonate treatment: experience in two large United Kingdom teaching hospitals
    R N Thompson
    Royal Victoria Hospital, Department of Trauma and Orthopaedics, Grosvenor Road, Belfast BT12 6BA, UK
    J Bone Joint Surg Br 94:385-90. 2012
    ..This large dual-centre review has established the incidence of atypical femoral fractures at 7% of the study population, 81% of whom had been on bisphosphonate treatment for a mean of 4.6 years (0...
  37. ncbi Computerised navigation for closed reduction during femoral intramedullary nailing
    Rami Mosheiff
    Department of Orthopaedic Surgery, The Hadassah Hebrew University Medical School, P O Box 12000, Ein Kerem, Jerusalem IL 91120, Israel
    Injury 36:866-70. 2005
  38. ncbi The cortical step sign as a tool for assessing and correcting rotational deformity in femoral shaft fractures
    Jakub S Langer
    Department of Orthopedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Orthop Trauma 24:82-8. 2010
    ..This study aims to critically analyze the cortical step sign in cadaveric specimens using radiographic and direct measurements...
  39. ncbi Ballistic fractures: indirect fracture to bone
    Paul J Dougherty
    Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Trauma 71:1381-4. 2011
    ....
  40. ncbi Intraoperative cone-beam CT for correction of periaxial malrotation of the femoral shaft: a surface-matching approach
    Amal Khoury
    Hadassah University Medical Centre, Department of Orthopaedic Surgery, Ein Kerem, Jerusalem 91120
    Med Phys 34:1380-7. 2007
    ..49 degrees. CBCT can provide intraoperative high-resolution images with a large field of view. This quality of imaging enables surface matching algorithms to be utilized even with large areas of comminution...
  41. ncbi The effect of bone morphogenetic protein-2, bone morphogenetic protein-7, parathyroid hormone, and platelet-derived growth factor on the proliferation and osteogenic differentiation of mesenchymal stem cells derived from osteoporotic bone
    Ippokratis Pountos
    Academic Department of Trauma and Orthopaedics, School of Medicine, University of Leeds, Leeds, UK
    J Orthop Trauma 24:552-6. 2010
    ....
  42. ncbi Femoral fractures in adolescents: a comparison of four methods of fixation
    Leonhard E Ramseier
    Hospital for Sick Children, Toronto, Ontario, Canada
    J Bone Joint Surg Am 92:1122-9. 2010
    The optimal management of femoral fractures in adolescents is controversial. This study was performed to compare the results and complications of four methods of fixation and to determine the factors related to those complications.
  43. ncbi Femoral nonunion: risk factors and treatment options
    Joseph R Lynch
    Department of Orthopaedics and Sports Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA
    J Am Acad Orthop Surg 16:88-97. 2008
    ..b>Femoral fractures may fail to unite because of the severity of the injury, damage to the surrounding soft tissues, inadequate ..
  44. pmc Vascular endothelial growth factor stimulates bone repair by promoting angiogenesis and bone turnover
    John Street
    Department of Academic Surgery, National University of Ireland, University College Cork, Cork, Ireland
    Proc Natl Acad Sci U S A 99:9656-61. 2002
    ..a soluble, neutralizing VEGF receptor decreased angiogenesis, bone formation, and callus mineralization in femoral fractures. Inhibition of VEGF also dramatically inhibited healing of a tibial cortical bone defect, consistent with ..
  45. ncbi Less invasive stabilisation system (LISS) for the treatment of periprosthetic femoral fractures: a 3-year follow-up
    Philipp Kobbe
    Department of Orthopaedic Trauma Surgery, Braunschweig, Germany
    Injury 39:472-9. 2008
    ..have reported encouraging results with a locked plating system in the management of periprosthetic femoral fractures. However, data on mid- or long-term functional outcome is not available...
  46. ncbi A comparison of the proximal femoral nail antirotation device and dynamic hip screw in the treatment of unstable pertrochanteric fracture
    Y Z Xu
    Department of Orthopaedics, First Affiliated Hospital of Soochow University, Suzhou, China
    J Int Med Res 38:1266-75. 2010
    ..All fractures in both groups united during follow-up. The PFNA allowed earlier mobilization and faster recovery than the DHS. The PFNA is a highly acceptable, minimally invasive implant for unstable fractures...
  47. ncbi Pediatric femoral fractures: a systematic review of 2422 cases
    Rudolf W Poolman
    Department of Orthopaedic Surgery, McMaster University, Hamilton, Ontario, Canada
    J Orthop Trauma 20:648-54. 2006
    The incidence of femoral fractures in children comprise 20 per 100,000 yearly in the United States and Europe. The treatment of femoral shaft fractures in the pediatric population remains controversial...
  48. ncbi Early results of the less invasive stabilization system for mechanically unstable fractures of the distal femur (AO/OTA types A2, A3, C2, and C3)
    Mark Weight
    Harris Methodist Hospital Fort Worth and Fort Worth Affiliated Hospitals John Peter Smith Orthopaedic Surgery Residency, Fort Worth, TX, USA
    J Orthop Trauma 18:503-8. 2004
    ..The purpose of this study is to evaluate the clinical results of patients with high energy, mechanically unstable fractures of the distal femur treated with the Less Invasive Stabilization System...
  49. ncbi Titanium elastic nails for pediatric femur fractures: a multicenter study of early results with analysis of complications
    J M Flynn
    Division of Orthopaedics, The Children s Hospitals of Philadelphia, Pennsylvania 19104 4399, USA
    J Pediatr Orthop 21:4-8. 2001
    ..As indications, implantation technique, and aftercare are refined, TENs may prove to be the ideal implant to stabilize many pediatric femur fractures, avoiding the prolonged immobilization and complications of traction and spica casting...
  50. ncbi Use of flexible intramedullary nail fixation in treating femur fractures in children
    Michael Khazzam
    Department of Orthopaedics, University of Missouri, Columbia, Missouri, USA
    Am J Orthop (Belle Mead NJ) 38:E49-55. 2009
    ..7%. These results demonstrate that use of flexible intramedullary nails in the treatment of femoral shaft fractures in children is successful regardless of patient age, fracture location, or fracture pattern...
  51. ncbi Refracture following plate removal in supracondylar-intercondylar femur fractures
    Brian L Davison
    Grant Medical Center, Columbus, Ohio, USA
    Orthopedics 26:157-9. 2003
    ..All refractures occurred during normal functional activities. Patients who request hardware removal following union of a distal femur fracture treated with open reduction and plating should be informed of the possibility of refracture...
  52. ncbi Incidence and demography of femur fractures with and without atypical features
    Adrianne C Feldstein
    Kaiser Permanente Center for Health Research, Portland, OR 97227 1110, USA
    J Bone Miner Res 27:977-86. 2012
    ..5 years. Patients with only AFMs appear to be different from those with AFMms; it may be that only the latter group is atypical. There appear to be multiple associated risk factors for AFMm fractures...
  53. pmc Comparison of mechanical rigidity between plate augmentation leaving the nail in situ and interlocking nail using cadaveric fracture model of the femur
    Kyungho Park
    Department of Orthopaedics, Kwangju Christian Hospital, Gwangju, Korea
    Int Orthop 35:581-5. 2011
    ..0001). We found a 2.6-fold increase in bending stiffness and a 3.3-fold increase in torsional stiffness in plate augmentation leaving a nail in situ compared to interlocking nailing only in the distal third fracture of femur...
  54. ncbi Gender affects macrophage cytokine and prostaglandin E2 production and PGE2 receptor expression after trauma
    Philip P Stapleton
    Weill Medical College of Cornell University, Department of Surgery, New York, New York, USA
    J Surg Res 122:1-7. 2004
    ..This study determined prostaglandin receptor subtype (EP1-EP4) expression following injury and determined whether gender differences influence EP receptor expression...
  55. ncbi Distal femoral fixation: a biomechanical comparison of trigen retrograde intramedullary (i.m.) nail, dynamic condylar screw (DCS), and locking compression plate (LCP) condylar plate
    Jake P Heiney
    Department of Orthopaedic Surgery, ProMedica Health System, Toledo, Ohio, USA
    J Trauma 66:443-9. 2009
    ..The purpose of this study was to establish if there are biomechanical differences between implants in stiffness of construct, microdisplacement, and fatigue failure in a supracondylar femoral fracture model...
  56. ncbi Changes in the stiffness, strength, and toughness of human cortical bone with age
    P Zioupos
    Department of Biology, University of York, York, UK
    Bone 22:57-66. 1998
    ..The macrocrack was preceded by less damage, and once created needed less energy to drive through the tissue (Wf)...
  57. ncbi The value of a prognostic scoring system in the rehabilitation of elderly patients with proximal femoral fractures
    M A Hashmi
    Freeman Hospital, Newcastle upon Tyne, UK
    Int J Clin Pract 58:2-5. 2004
    ....
  58. ncbi Retrograde intramedullary nailing in distal femoral fractures--results in a series of 46 consecutive operations
    Lauri Handolin
    Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Topeliuksenkatu 5, Helsinki 00260, Finland
    Injury 35:517-22. 2004
    We present a series of 44 consecutive patients with 46 distal femoral fractures, who were treated with a retrograde intramedullary nail (Distal Femoral Nail (DFN))...
  59. ncbi Locking plates for distal femur fractures: is there a problem with fracture healing?
    Christopher E Henderson
    Orthopaedic Surgery, University of Iowa Hospital and Clinics, Iowa City, IA, USA
    J Orthop Trauma 25:S8-14. 2011
    ..This article reviews the literature on distal femur fractures treated with locking plates to determine the reported rate of healing difficulties...
  60. ncbi Reverse LISS plates for unstable proximal femoral fractures
    Ching Hou Ma
    Department of Orthopaedics, E Da Hospital I Shou University, No 1, E Da Road, Jiau Shu Tsuen, Yan Chau Shiang, Kaohsiung 824, Taiwan
    Injury 41:827-33. 2010
    The best treatment for unstable proximal femoral fractures is controversial...
  61. ncbi The outcome of surgically treated femur fractures associated with long-term bisphosphonate use
    Yoram A Weil
    Department of Orthopaedics, Hadassah Hebrew University Hospital, Jerusalem, Israel
    J Trauma 71:186-90. 2011
    ..The aim of this study was to describe the outcome of surgically treated femur fractures associated with prolonged BP use...
  62. pmc Proximal femoral nail - an analysis of 100 cases of proximal femoral fractures with an average follow up of 1 year
    W M Gadegone
    Department of Orthopaedic and Traumatology, Chandrapur Multispeciality Hospital, Mul Road, Chandrapur 442401, India
    Int Orthop 31:403-8. 2007
    ..Osteosynthesis with the PFN offers the advantages of high rotational stability of the head-neck fragment, an unreamed implantation technique and the possibility of static or dynamic distal locking...
  63. ncbi Stress fracture in military recruits: gender differences in muscle and bone susceptibility factors
    T J Beck
    Department of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD 21287 0849, USA
    Bone 27:437-44. 2000
    ..07). Unlike the bone geometry differences, thigh muscle cross-sectional areas were virtually identical to those of the men, suggesting that the muscles of the women were not relatively weaker...
  64. pmc Retrograde intramedullary nailing for periprosthetic supracondylar fractures of the femur after total knee arthroplasty
    Hyuk Soo Han
    Department of Orthopaedic Surgery, Seoul National University Boramae Medical Center, Seoul, Korea
    Clin Orthop Surg 1:201-6. 2009
    ..This study evaluated the efficacy of retrograde intramedullary nailing for the treatment of periprosthetic supracondylar fractures of the femur using the clinical outcomes...
  65. ncbi Austin-Moore hemiarthroplasty for failed osteosynthesis of intracapsular proximal femoral fractures
    C Roberts
    Department of Orthopaedics, Addenbrooke s Hospital, Hills Road, Peterborough, Cambs CB2 2QQ, UK
    Injury 33:423-6. 2002
    ..Austin-Moore hemiarthroplasties used as a revision procedure for failed osteosynthesis of intracapsular femoral fractures. This group was compared with 730 patients in whom an uncemented Austin-Moore prosthesis had been used as ..
  66. ncbi Pathophysiology of atypical femoral fractures and osteonecrosis of the jaw
    J Compston
    Cambridge University Hospitals NHS Foundation Trust, Cambridge, CB2 0QQ, UK
    Osteoporos Int 22:2951-61. 2011
    In recent years, atypical femoral fractures and osteonecrosis of the jaw have emerged as potential complications of long-term bisphosphonate therapy; osteonecrosis of the jaw has also been reported in patients receiving high doses of ..
  67. ncbi [Animal models for bone and joint disease. Animal fracture model and fracture healing process]
    Tasuku Mashiba
    Department of Orthopedic Surgery, Kagawa University Faculty of Medicine
    Clin Calcium 21:235-41. 2011
    ..Fracture healing is completed by not only bone union of fracture site but restoration of original bony shape and bone quality due to progression of callus remodeling...
  68. ncbi Elastic stable intramedullary nailing in pediatric femur and lower leg shaft fractures: intraoperative radiation load
    Ralf Kraus
    Department of Trauma Surgery, University Hospital Giessen and Marburg, Giessen, Germany
    J Pediatr Orthop 28:14-6. 2008
    ..Literature concerning intraoperative radiation load in ESIN is rare, results having a wide range from less than 1 minute to more than 15 minutes...
  69. ncbi Surgical treatment of femoral fractures in obese children: does excessive body weight increase the rate of complications?
    Arabella I Leet
    Department of Orthopaedic Surgery, Johns Hopkins University, 601 North Caroline Street, Room 5255, Baltimore, MD 21287 0882, USA
    J Bone Joint Surg Am 87:2609-13. 2005
    ..In light of the increasing rate of obesity among children in the United States, this study examines whether obese children have an increased rate of complications following surgical treatment of femoral shaft fractures...
  70. ncbi Complications of titanium elastic nails for pediatric femoral shaft fractures
    Scott J Luhmann
    Department of Orthopaedic Surgery, Washington University School of Medicine and St Louis Children s Hospital, Missouri 63110, USA
    J Pediatr Orthop 23:443-7. 2003
    ..Technical pitfalls exist with this implant and can be minimized by leaving less than 2.5 cm of nail out of the femur and by using the largest nail sizes possible...
  71. ncbi Intramedullary nailing of femoral fractures in adolescents
    N Momberger
    Department of Orthopedics, University of Utah, Salt Lake City, USA
    J Pediatr Orthop 20:482-4. 2000
    ..Intramedullary nailing through a trochanteric starting point is a safe, effective method for treating femur fractures in this adolescent age group...
  72. ncbi Effects of calcium supplements on fracture healing in a rat osteoporotic model
    Ahmad Nazrun Shuid
    Department of Pharmacology, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Raja Muda Abd Aziz, 50300 KL, Malaysia
    J Orthop Res 28:1651-6. 2010
    ..Therefore, calcium supplements may appear to improve fracture healing of osteoporotic bone but failed to improve strength...
  73. ncbi Ender nail fixation of pediatric femur fractures: a biomechanical analysis
    S S Lee
    Children's Hospital and Health Center and University of California at San Diego, San Diego, California 92123-4293
    J Pediatr Orthop 21:442-5. 2001
    ..These data suggest that length and rotational control of comminuted midshaft femur fractures with two divergent Ender nails may be sufficient for early mobilization...
  74. ncbi Biomechanical comparison of flexible stainless steel and titanium nails with external fixation using a femur fracture model
    Usha S Mani
    Department of Orthopedics Research Laboratory, UMDNJ New Jersey Medical School, Newark, NJ 07103, USA
    J Pediatr Orthop 26:182-7. 2006
    ..No significant benefit was demonstrated with double stacking of external fixators. These findings may help guide clinicians choose the optimal fixation method for treatment of pediatric femoral shaft fractures...
  75. ncbi Titanium elastic nailing of fractures of the femur in children. Predictors of complications and poor outcome
    L A Moroz
    Department of Orthopaedic Surgery, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania 19104 4399, USA
    J Bone Joint Surg Br 88:1361-6. 2006
    ..003). A poor outcome was five times more likely in children who weighed more than 49 kg...
  76. ncbi Resuscitation before stabilization of femoral fractures limits acute respiratory distress syndrome in patients with multiple traumatic injuries despite low use of damage control orthopedics
    Robert V O'Toole
    Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 67:1013-21. 2009
    ..Our approach to treating femoral fractures in patients with multiple traumatic injuries is to perform reamed nailing after adequate resuscitation has ..
  77. ncbi Fragility fractures of the hip and femur: incidence and patient characteristics
    J W Nieves
    Department of Epidemiology, Columbia University, New York, NY, USA
    Osteoporos Int 21:399-408. 2010
    Using national discharge and medical claims data, we studied the epidemiology of femoral fractures from 1996 to 2006...
  78. ncbi Stimulation of the local femoral inflammatory response to fracture and intramedullary reaming: a preliminary study of the source of the second hit phenomenon
    J R Morley
    Academic Department of Orthopaedic and Trauma Surgery, Leeds University, The General Infirmary at Leeds, Clarendon Wing, Great George Street, Leeds LS1 3EX, UK
    J Bone Joint Surg Br 90:393-9. 2008
    ..In patients who underwent intramedullary reaming of the femoral canal a further significant local release of IL-6 was demonstrated, providing evidence that intramedullary reaming can cause a significant local inflammatory reaction...
  79. ncbi Compression plating of pediatric femoral shaft fractures
    Michelle S Caird
    Department of Orthopaedic Surgery, University of Michigan, Ann Arbor, Michigan 48109, USA
    J Pediatr Orthop 23:448-52. 2003
    ..Compression plate fixation is a safe and effective treatment in children with both isolated femoral shaft fractures and those associated with multiple injuries...
  80. ncbi Proximal femoral radiographic changes after lateral transtrochanteric intramedullary nail placement in children
    J Eric Gordon
    Washington University School of Medicine, St Louis Shriners Hospital for Children, Missouri, USA
    J Bone Joint Surg Am 85:1295-301. 2003
    ..The mean age of the patients at the time of the index procedure was ten years and six months...
  81. ncbi Effect of 1,25-dihydroxy vitamin D3 on fracture healing and bone remodeling in ovariectomized rat femora
    Lingjie Fu
    Department of Orthopaedic Surgery, Ninth People s Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, PR China
    Bone 44:893-8. 2009
    ..In conclusion, 1,25(OH)(2)D(3) could promote fracture healing by improving the histomorphometric parameters, mechanical strength and tendency to increase transformation of woven bone into lamellar bone in an ovariectomized rat model...
  82. ncbi Systemic inflammatory response after extremity or truncal fracture operations
    Hans Christoph Pape
    Department of Orthopaedic Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA
    J Trauma 65:1379-84. 2008
    ..The purpose of this study was to assess proinflammatory markers in blunt trauma patients regarding the relationship of these and blood loss and duration of surgery in different fracture locations...
  83. pmc Case report : femoral shaft fracture resulting from femoral tracker placement in navigated TKA
    Peter Bonutti
    St Anthony s Hospital, Effingham, IL, USA
    Clin Orthop Relat Res 466:1499-502. 2008
    ..We report two patients with displaced femoral fractures at optical tracker pin placement sites created for routine performance of navigated TKA...
  84. ncbi Management of pediatric femoral shaft fractures
    John M Flynn
    Division of Orthopaedic Surgery, The Children s Hospital of Philadelphia, 2nd Floor Wood Building, 34th and Civic Center Boulevard, Philadelphia, PA 19104, USA
    J Am Acad Orthop Surg 12:347-59. 2004
    ..Risks of surgical management include refracture after external fixator or plate removal, osteonecrosis after rigid antegrade intramedullary nail fixation, and soft-tissue irritation caused by the ends of flexible nails...
  85. pmc Antipsychotic use and the risk of hip/femur fracture: a population-based case-control study
    S Pouwels
    Department of Pharmacoepidemiology and Pharmacotherapy, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands
    Osteoporos Int 20:1499-506. 2009
    ..Furthermore, no evidence for a dose effect was found...
  86. ncbi The science of fracture healing
    Thomas A Einhorn
    Boston University Medical Center, Department of Orthopaedic Surgery, Boston, MA 02118, USA
    J Orthop Trauma 19:S4-6. 2005
    ..This article summarizes the series of cellular and molecular events that take place in the process of endochondral fracture healing, based on observations obtained from an animal model of a femoral fracture...
  87. ncbi The risk of child abuse in infants and toddlers with lower extremity injuries
    Carla Coffey
    The Trauma Program, Children s Hospital, Columbus, OH 43205, USA
    J Pediatr Surg 40:120-3. 2005
    ..The aim of this study was to assess the risk of child abuse in children younger than 18 months admitted to a pediatric trauma service with lower extremity injuries...
  88. ncbi A biomechanical study on flexible intramedullary nails used to treat pediatric femoral fractures
    Jason K Green
    Department of Orthopedic Surgery, SUNY Upstate Medical University, 3214 Institute for Human Performance, 505 Irving Avenue Syracuse, NY 13210, USA
    J Orthop Res 23:1315-20. 2005
    Flexible intramedullary nails have been indicated to treat femoral fractures in pediatric patients...
  89. pmc Use of anti-depressants and the risk of fracture of the hip or femur
    M W M van den Brand
    Department of Geriatric Medicine, University Medical Centre Utrecht, Heidelberglaan 100, 3584 CX, Utrecht, The Netherlands
    Osteoporos Int 20:1705-13. 2009
    ..This should be considered when prescribing anti-depressants to patients...
  90. ncbi Features of femoral fractures in nonaccidental injury
    C Rex
    Manchester Children s Hospitals, University of Manchester, United Kingdom
    J Pediatr Orthop 20:411-3. 2000
    ..It is important medicolegally to establish a diagnosis of child abuse. Fourteen femoral fractures from definite nonaccidental injury were analysed and compared with 33 femoral fractures caused by definite ..
  91. ncbi Computer navigation allows for accurate reduction of femoral fractures
    Yoram A Weil
    Orthopaedic Trauma Service, Hospital for Special Surgery, New York, NY, USA
    Clin Orthop Relat Res 460:185-91. 2007
    Femoral nailing for reduction and stabilization of femoral fractures is a common orthopaedic procedure. However, angular and rotational malalignment is not an infrequent result, and extensive use of fluoroscopy is commonly involved...
  92. ncbi Intermittent PTH(1-34) does not increase union rates in open rat femoral fractures and exhibits attenuated anabolic effects compared to closed fractures
    Magnus Tagil
    Orthopaedic Research and Biotechnology, The Children s Hospital, Westmead, Australia
    Bone 46:852-9. 2010
    ..In the open fractures that did unite, a muted response to PTH was seen compared to closed fractures. Further research is required to determine if PTH((1-34)) is an appropriate anabolic treatment for open fractures...
  93. ncbi Child abuse in infants with proximal physeal injuries of the femur
    Joshua C W Jones
    General Pediatric Division, Department of Pediatrics, University of Washington School of Medicine, Seattle, WA, USA
    Pediatr Emerg Care 20:157-61. 2004
    ..Fractures of the proximal femoral physis in abused infants have been less emphasized. Our report seeks to highlight this infrequent but clinically important inflicted injury...
  94. pmc The threshold force required for femoral impaction grafting in revision hip surgery
    Olivia M Flannery
    Trinity Centre for Bioengineering, School of Engineering, Trinity College, Dublin, Ireland
    Acta Orthop 81:303-7. 2010
    ..Femoral impaction grafting requires vigorous impaction to obtain adequate stability without risk of fracture, but the force of impaction has not been determined. We determined this threshold force in a preliminary study using animal femurs...
  95. ncbi Biomechanical analysis of antegrade and retrograde flexible intramedullary nail fixation of pediatric femoral fractures using a synthetic bone model
    Kevin B Fricka
    Department of Orthopaedic Surgery, Children s Hospital, San Diego, California, USA
    J Pediatr Orthop 24:167-71. 2004
    Biomechanical testing was performed to evaluate the stability of simulated transverse and comminuted femoral fractures after retrograde and antegrade flexible titanium intramedullary nail fixation...
  96. ncbi Evolution of minimally invasive plate osteosynthesis (MIPO) in the femur
    C Krettek
    Trauma Department, Hannover Medical School, Germany
    Injury 32:SC14-23. 2001
    Problems with conventional open reduction and internal plate fixation of distal femoral fractures are well established. These problems have been associated with extensile exposures of the fracture site...
  97. ncbi Intramedullary nailing of femoral shaft fractures: current concepts
    William M Ricci
    Department of Orthopaedic Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Am Acad Orthop Surg 17:296-305. 2009
    ..This method yields high union rates and low complication rates when vigilance is maintained during preoperative planning, the surgical procedure, and the postoperative period...
  98. ncbi VEGF serum concentrations in patients with long bone fractures: a comparison between impaired and normal fracture healing
    Kambiz Sarahrudi
    Department of Traumatology, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    J Orthop Res 27:1293-7. 2009
    ....
  99. ncbi A novel, non-prostanoid EP2 receptor-selective prostaglandin E2 agonist stimulates local bone formation and enhances fracture healing
    Mei Li
    Department of Cardiovascular and Metabolic Diseases, Pfizer Global Research and Development, Groton Laboratories, Groton, Connecticut 06340, USA
    J Bone Miner Res 18:2033-42. 2003
    ..CP-533,536, a newly discovered, non-prostanoid EP2 receptor-selective PGE2 agonist, stimulates local bone formation and enhances fracture healing in rat models...
  100. ncbi Biomechanical evaluation of the less invasive stabilization system, angled blade plate, and retrograde intramedullary nail for the internal fixation of distal femur fractures
    Michael Zlowodzki
    Department of Orthopedic Surgery, University of Minnesota, Regions Hospital, St Paul, MN, USA
    J Orthop Trauma 18:494-502. 2004
    ..To evaluate the stability of the retrograde intramedullary nail (IMN), angled blade plate (ABP), and a locked internal fixator (Less Invasive Stabilization System [LISS], Synthes, Paoli, PA) for internal fixation of distal femur fractures...
  101. ncbi Microdamage of human cortical bone: incidence and morphology in long bones
    T L Norman
    Department of Mechanical and Aerospace Engineering, West Virginia University, Morgantown 26506 9196, USA
    Bone 20:375-9. 1997
    ..It was also found that microdamage increased with age, was significantly greater in females than males, and was significantly greater in the proximal femur than the midshaft of the tibia...

Research Grants43

  1. Modeling fracture prediction in spinal cord injury and disease
    Laura D Carbone; Fiscal Year: 2013
    ..side effects from pharmacological therapies for osteoporosis including osteonecrosis of the jaw and atypical femoral fractures have been reported...
  2. TNSALP Mutations in Atypical Femoral Fractures with Long-Term Bisphosphonate Use
    STEVEN R MUMM; Fiscal Year: 2013
    ..for Bone and Mineral Research to investigate the association of atypical subtrochanteric and diaphyseal femoral fractures (ASFFs) with the long-term use of bisphosphonates for osteoporosis...
  3. IBMS Sun Valley Workshop on Musculoskeletal Biology
    David B Burr; Fiscal Year: 2013
    ..both themes by addressing osteocyte signaling in the repair of stress fractures, relating this to atypical femoral fractures. Many opportunities are provided for junior investigators to interact with more senior investigators...
  4. Pathogenesis of Atypical Femur Fractures on Long Term Bisphosphonate Therapy
    D Sudhaker Rao; Fiscal Year: 2013
    ..However, since 2005 there have been many reports of atypical femoral fractures (AFF) in patients on prolonged BP therapy...
  5. Unintended muscle activity influences on post-stroke locomotion
    CITLALI LOPEZ ORTIZ; Fiscal Year: 2007
    ..body during locomotion and place individuals with post-stroke hemiplegia at high risk for frequent falls and femoral fractures. Thus, it is necessary to study muscle coordination patterns to identify the underlying causative mechanisms ..
  6. Molecular Mechanisms of Skeletal Repair
    Thomas Einhorn; Fiscal Year: 2008
    ..Successful establishment and implementation of this program will greatly enhance the coordinated activities of this team of investigators and lead to important new results and directions for skeletal healing research. ..
  7. MUSCULOSKELETAL TRAINING GRANT
    David Burr; Fiscal Year: 2006
    ..Two presentations were nominated for Young Investigator Awards by the ASBMR and the ORS. ..
  8. Sun Valley Workshop on Skeletal Biology
    David Burr; Fiscal Year: 2004
    ..An Advisory Panel is formed of session chairs. There are plans to advertise and distribute a summary of the workshop, partly using Web-based resources. ..
  9. Sun Valley Workshop on Skeletal Biology
    David Burr; Fiscal Year: 2006
    ..There are plans to advertise and distribute a summary of the workshop, partly using Web-based resources. [unreadable] [unreadable] [unreadable] [unreadable]..
  10. Sun Valley Workshop on Skeletal Biology
    David Burr; Fiscal Year: 2007
    ..There are plans to advertise and distribute a summary of the workshop, partly using Web-based resources. [unreadable] [unreadable] [unreadable] [unreadable]..
  11. Sun Valley Workshop on Skeletal Biology
    David Burr; Fiscal Year: 2005
    ..An Advisory Panel is formed of session chairs. There are plans to advertise and distribute a summary of the workshop, partly using Web-based resources. ..
  12. Sun Valley Workshop on Skeletal Biology
    David Burr; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  13. TWO X-LINKED GENES THAT REGULATE MINERAL HOMEOSTASIS
    Michael Whyte; Fiscal Year: 2002
    ....
  14. Genes Controlling the Renal Handling of Phosphate
    Ralph Meyer; Fiscal Year: 2004
    ..Such intervention may improve the skeletal symptoms of patients with hypophosphatemic bone disease and improve their quality of life. ..
  15. Hip Fracture Evaluation Alternatives of Total Hip vs Hemi-arthroplasty (HEALTH)
    Thomas Einhorn; Fiscal Year: 2009
    ..Potential Impact: This trial will not only change current orthopaedic practice, but will set a benchmark for the conduct of future orthopaedic trials. ..
  16. MECHANOTRANSDUCTION IN BONE
    David Burr; Fiscal Year: 2003
    ..Data generated by this Program are intended to define some mechanisms by which fluid forces can regulate gene expression, and will attempt to validate these mechanisms by in vivo studies. ..
  17. Forging Implementation of Cancer Screening Reminder Systems (FICSRS)
    Adrianne Feldstein; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  18. EFFECTS OF AGE ON SIGNALING IN HUMAN OSTEOBLASTOGENESIS
    Julie Glowacki; Fiscal Year: 2010
    ....
  19. IDIOPATHIC OSTEOPOROSIS IN PREMENOPAUSAL WOMEN
    Elizabeth Shane; Fiscal Year: 2009
    ..The results of these studies will have important therapeutic implications for the diagnosis and management of this disorder. ..
  20. A Virtual Reality Based Joint Injection Simulator Phase II
    Karl Reinig; Fiscal Year: 2007
    ..The system is designed to reduce the trainee's dependence on patients as training devices. [unreadable] [unreadable] [unreadable]..
  21. MAP KINASE REGULATION OF OSTEOBLAST FUNCTION
    Renny Franceschi; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  22. TISSUE ENGINEERING OF GROWING JOINTS
    Julie Glowacki; Fiscal Year: 2002
    ..In vivo fate of engineered joints will be assessed in our model of murine joint transplantation and will be further verified in the pig. ..
  23. A VIRTUAL ENVIRONMENT FOR ARTHROSCOPY SIMULATION
    Karl Reinig; Fiscal Year: 2003
    ..It will also provide a platform for orthopedic tool and device makers to introduce and to train doctors on their new developments. ..
  24. BONE SIALOPROTEIN: EXPRESSION & ROLE IN MINERALIZATION
    Renny Franceschi; Fiscal Year: 2004
    ..Such knowledge is essential for designing new strategies for bone regeneration to treat trauma and pathological conditions such as osteoporosis and periodontal disease. ..
  25. Prevention of Osteoporosis after Transplantation
    Elizabeth Shane; Fiscal Year: 2002
    ..We are now applying for 3 years of support to complete 12 months of observation on those subjects enrolled after March, 2001 and to complete an additional 24 months of follow-up on enrolled participants. ..
  26. A Whole Body, Multi-Purpose, Ultrasound Simulator
    Karl Reinig; Fiscal Year: 2005
    ....
  27. Bioreactor Expansion and Transplantation of ES Cell Derived Osteoblasts and Chond
    John Matyas; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  28. TISSUE STRESS VARIABILITY AND STRENGTH IN VERTEBRAL BONE
    Yener Yeni; Fiscal Year: 2006
    ..abstract_text> ..
  29. Weight in Secondary Prevention (WISP)
    Adrianne Feldstein; Fiscal Year: 2006
    ..Understanding which patients will need the most support to manage weight will allow us to design the most cost-effective future programs. ..
  30. Pregnancy Outcomes in Polycystic Ovary Syndrome
    Joan Lo; Fiscal Year: 2009
    ....
  31. BISPHOSPHONATE BONE QUALITY IN WOMEN WITH BREAST CANCER
    Susan Ott; Fiscal Year: 2009
    ..Results of the study will provide valuable information about skeletal effects of high-dose bisphosphonates in humans. ..
  32. Rabbit Model for In Vivo Monitoring of Bone Structure
    Michael Voor; Fiscal Year: 2003
    ..It will give investigators the opportunity to watch the specific trabecular surfaces that are affected by various treatments and to observe when these effects occur. ..
  33. Effect of Aging & Vitamin D Status on Osteoblastogenesis
    Julie Glowacki; Fiscal Year: 2008
    ..abstract_text> ..
  34. Fatigue Crack Morphology in Cemented Hips
    Amos Race; Fiscal Year: 2002
    ....
  35. Spectroscopic X-ray Bone Densitometry
    Thomas Beck; Fiscal Year: 2008
    ..The disease is characterized by low bone mass, leading to enhanced bone fragility and a significant increase in the risk of fractures, which is typically diagnosed by bone densitometer [1,2]. [unreadable] [unreadable] [unreadable]..
  36. Effect of Femoral Stem Design om Cement Mantle Failure
    Amos Race; Fiscal Year: 2006
    ..Should these aims be met, the proposed model will be of great use in pre-clinical testing of novel cemented stem designs. ..
  37. Clinical Decision Rule to Identify Children with Intra-Abdominal Injuries
    James Holmes; Fiscal Year: 2008
    ..unreadable]..
  38. Sphingosine 1-phosphate and PMN Ca2+ entry in trauma
    Carl Hauser; Fiscal Year: 2009
    ..Determine the side effects and complications of SOCE inhibition after shock. 3. Determine the effects of injury on intracellular S1P/SOCE signaling 4. Determine the mechanisms by which circulating S1P activates PMN after trauma. ..
  39. Induced hypothermic arrest in traumatic shock
    Hasan Alam; Fiscal Year: 2005
    ..Sub aim 2: Develop and test methods and techniques that can facilitate the induction of hypothermic arrest in the setting of traumatic shock. ..