substance induced psychoses

Summary

Summary: Psychotic organic mental disorders resulting from the toxic effect of drugs and chemicals or other harmful substance.

Top Publications

  1. ncbi [Increasing prevalence of amphetamine--and methamphetamine-induced psychosis]
    Roland Härtel-Petri
    Abteilung Klinische Suchtmedizin, Klinik fur Psychiatrie und Psychotherapie, Bezirkskrankenhaus Bayreuth
    Psychiatr Prax 32:13-7. 2005
  2. pmc Psychological effects of ketamine in healthy volunteers. Phenomenological study
    E Pomarol-Clotet
    Benito Menni CASM, Barcelona, Spain
    Br J Psychiatry 189:173-9. 2006
  3. ncbi The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for psychosis
    DEEPAK CYRIL D'SOUZA
    Schizophrenia Biological Research Center, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Neuropsychopharmacology 29:1558-72. 2004
  4. ncbi Clinical features of sensitization to methamphetamine observed in patients with methamphetamine dependence and psychosis
    Hiroshi Ujike
    Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Ann N Y Acad Sci 1025:279-87. 2004
  5. ncbi Effects of (S)-ketamine on striatal dopamine: a [11C]raclopride PET study of a model psychosis in humans
    F X Vollenweider
    Psychiatric University Hospital Zurich, Research Department, Switzerland
    J Psychiatr Res 34:35-43. 2000
  6. ncbi Effects of NMDA antagonism on striatal dopamine release in healthy subjects: application of a novel PET approach
    A Breier
    Experimental Therapeutics Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Synapse 29:142-7. 1998
  7. ncbi Metabolic hyperfrontality and psychopathology in the ketamine model of psychosis using positron emission tomography (PET) and [18F]fluorodeoxyglucose (FDG)
    F X Vollenweider
    Research Department, Psychiatric University Hospital of Zurich, Switzerland
    Eur Neuropsychopharmacol 7:9-24. 1997
  8. ncbi Relationship between ketamine-induced psychotic symptoms and NMDA receptor occupancy: a [(123)I]CNS-1261 SPET study
    James M Stone
    Institute of Psychiatry, King s College London, London, UK
    Psychopharmacology (Berl) 197:401-8. 2008
  9. ncbi Psychopathological consequences of ketamine
    J M Stone
    Br J Psychiatry 189:565-6. 2006
  10. ncbi Inhibition of return in the human 5HT2A agonist and NMDA antagonist model of psychosis
    Euphrosyne Gouzoulis-Mayfrank
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Neuropsychopharmacology 31:431-41. 2006

Research Grants

Detail Information

Publications188 found, 100 shown here

  1. ncbi [Increasing prevalence of amphetamine--and methamphetamine-induced psychosis]
    Roland Härtel-Petri
    Abteilung Klinische Suchtmedizin, Klinik fur Psychiatrie und Psychotherapie, Bezirkskrankenhaus Bayreuth
    Psychiatr Prax 32:13-7. 2005
    ..In some regions methamphetamin is particularly common. Flashbacks, which can be triggered by psychosocial stress, as well as the age of the usually young patients lead to the differential diagnosis of schizophrenia...
  2. pmc Psychological effects of ketamine in healthy volunteers. Phenomenological study
    E Pomarol-Clotet
    Benito Menni CASM, Barcelona, Spain
    Br J Psychiatry 189:173-9. 2006
    ..The psychosis-inducing effect of ketamine is important evidence supporting the glutamate hypothesis of schizophrenia. However, the symptoms the drug produces have not been described systematically...
  3. ncbi The psychotomimetic effects of intravenous delta-9-tetrahydrocannabinol in healthy individuals: implications for psychosis
    DEEPAK CYRIL D'SOUZA
    Schizophrenia Biological Research Center, VA Connecticut Healthcare System, West Haven, CT 06516, USA
    Neuropsychopharmacology 29:1558-72. 2004
    ..These data warrant further study of whether brain cannabinoid receptor function contributes to the pathophysiology of psychotic disorders...
  4. ncbi Clinical features of sensitization to methamphetamine observed in patients with methamphetamine dependence and psychosis
    Hiroshi Ujike
    Department of Neuropsychiatry, Okayama University Graduate School of Medicine and Dentistry, Okayama, Japan
    Ann N Y Acad Sci 1025:279-87. 2004
    ..Molecular findings using animal sensitization models may facilitate a better understanding of, and open the way for innovative therapies for, METH psychosis and also chronic schizophrenia...
  5. ncbi Effects of (S)-ketamine on striatal dopamine: a [11C]raclopride PET study of a model psychosis in humans
    F X Vollenweider
    Psychiatric University Hospital Zurich, Research Department, Switzerland
    J Psychiatr Res 34:35-43. 2000
    ..These results provide evidence that the glutamatergic NMDA receptor may contribute to psychotic symptom formation via modulation of the DA system...
  6. ncbi Effects of NMDA antagonism on striatal dopamine release in healthy subjects: application of a novel PET approach
    A Breier
    Experimental Therapeutics Branch, Intramural Research Program, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland, USA
    Synapse 29:142-7. 1998
    ..The implications of this brain imaging method for studies of schizophrenia and the mechanism of action of antipsychotic drugs are discussed...
  7. ncbi Metabolic hyperfrontality and psychopathology in the ketamine model of psychosis using positron emission tomography (PET) and [18F]fluorodeoxyglucose (FDG)
    F X Vollenweider
    Research Department, Psychiatric University Hospital of Zurich, Switzerland
    Eur Neuropsychopharmacol 7:9-24. 1997
    ....
  8. ncbi Relationship between ketamine-induced psychotic symptoms and NMDA receptor occupancy: a [(123)I]CNS-1261 SPET study
    James M Stone
    Institute of Psychiatry, King s College London, London, UK
    Psychopharmacology (Berl) 197:401-8. 2008
    ..Ketamine induces effects resembling both positive and negative psychotic symptoms of schizophrenia. These are thought to arise through its action as an uncompetitive antagonist of the N-methyl-D-aspartate (NMDA) receptor...
  9. ncbi Psychopathological consequences of ketamine
    J M Stone
    Br J Psychiatry 189:565-6. 2006
  10. ncbi Inhibition of return in the human 5HT2A agonist and NMDA antagonist model of psychosis
    Euphrosyne Gouzoulis-Mayfrank
    Department of Psychiatry and Psychotherapy, University of Cologne, Germany
    Neuropsychopharmacology 31:431-41. 2006
    ..Blunted IOR may underlie or predispose to different psychotic manifestations, but particularly to those with prominent positive symptoms...
  11. ncbi Serotonin research: contributions to understanding psychoses
    Mark A Geyer
    Department of Psychiatry, University of California San Diego, Room B 418 Clinical Teaching Facility, 212 W Dickinson Street, San Diego, CA 92103, USA
    Trends Pharmacol Sci 29:445-53. 2008
    ..This review summarizes experimental assessments of the serotonergic hallucinogen model psychosis in relation to the serotonin hypothesis of schizophrenia...
  12. ncbi Frontal responses during learning predict vulnerability to the psychotogenic effects of ketamine: linking cognition, brain activity, and psychosis
    Philip R Corlett
    Brain Mapping Unit, Department of Psychiatry, School of Clinical Medicine, University of Cambridge, Cambridge, England
    Arch Gen Psychiatry 63:611-21. 2006
    ..Establishing a neurobiological account of delusion formation that links cognitive processes, brain activity, and symptoms is important to furthering our understanding of psychosis...
  13. ncbi Disturbances of visual information processing in early states of psychosis and experimental delta-9-tetrahydrocannabinol altered states of consciousness
    Dagmar Koethe
    Department of Psychiatry and Psychotherapy, University of Cologne, 50924 Cologne, Germany
    Schizophr Res 88:142-50. 2006
    ....
  14. ncbi [Reefer madness revisited: cannabis and psychosis]
    John Witton
    Rev Bras Psiquiatr 26:2-3. 2004
  15. ncbi Curses, madness, and mefloquine
    Oladipo Kukoyi
    Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
    Psychosomatics 44:339-41. 2003
  16. ncbi Psychotic symptoms in methamphetamine psychotic in-patients
    Manit Srisurapanont
    Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Int J Neuropsychopharmacol 6:347-52. 2003
    ..The clinical findings do not support the shortcomings of amphetamine-induced psychosis in modelling the negative symptoms of schizophrenia...
  17. ncbi Intoxication and settled insanity: a finding of not guilty by reason of insanity
    Jeff Feix
    Central State Hospital, Forensic Unit, 26317 Washington Street, Petersburg, VA 23803, USA
    J Am Acad Psychiatry Law 35:172-82. 2007
    ..The evaluating clinician must still determine, even when a threshold condition is considered to be present, whether statutory criteria for the insanity defense (for the jurisdiction in which the crime allegedly took place) are met...
  18. ncbi Determining vulnerability to schizophrenia in methamphetamine psychosis using exploratory eye movements
    Tomoko Mikami
    Section of Psychiatry and Behavioral Science, Graduate School of Tokyo Medical and Dental University, Tokyo, Japan
    Psychiatry Clin Neurosci 57:433-40. 2003
    ..It did not differ from that of the schizophrenic subjects. These results suggest that the severely disturbed group of patients with the persistent type of MAP psychosis have a vulnerability to schizophrenia...
  19. ncbi Neurocognitive dysfunction in first-episode psychosis: correlates with symptoms, premorbid adjustment, and duration of untreated psychosis
    Bjørn Rishovd Rund
    Department of Psychiatry, Ulleval University Hospital, Oslo, Norway
    Am J Psychiatry 161:466-72. 2004
    ....
  20. ncbi Cannabis and brain morphology in recent-onset schizophrenia
    W Cahn
    Schizophr Res 67:305-7. 2004
  21. ncbi Quetiapine improves psychotic symptoms and cognition in Parkinson's disease
    Jorge L Juncos
    Neurology Department, Emory University, Atlanta, Georgia 30329, USA
    Mov Disord 19:29-35. 2004
    ....
  22. ncbi Methamphetamine psychosis in which tardive dystonia was successfully treated with clonazepam
    Nobutomo Yamamoto
    Department of Psychiatry, Shimofusa Psychiatric Medical Center, Chiba City, Chiba, Japan
    Psychiatry Clin Neurosci 61:691-4. 2007
    ..Tardive dystonia is currently treated on a trial-and-error basis. Accumulation of further cases similar to the present one is very important for establishing an effective treatment...
  23. ncbi Dependence and chronic psychosis with D-nor-pseudoephedrine
    B Alevizos
    Department of Psychiatry, University of Athens, Eginition Hospital, 74 Vass Sophias Avenue, Athens 11528, Greece
    Eur Psychiatry 18:423-5. 2003
  24. ncbi Potential for antipsychotic and psychotomimetic effects of A2A receptor modulation
    Scott M Weiss
    Vernalis Research Ltd, Wokingham, UK
    Neurology 61:S88-93. 2003
    ..Preclinical studies using selective A2A receptor antagonists suggest that this class of compound has a low propensity to elicit psychotomimetic side effects or exacerbate those induced by D2 receptor agonists...
  25. ncbi Delusions incorporating cannabis use in dually diagnosed patients with a primary psychotic disorder
    Sarah E Flanders
    Department of Psychiatry, James Fletcher Hospital, Newcastle, NSW, Australia
    Aust N Z J Psychiatry 41:934-6. 2007
    ..To describe and discuss the implications for treatment of 3 cases of dually diagnosed patients with a primary psychotic disorder who have developed persisting, cannabis-oriented delusional systems...
  26. ncbi [Depression and schizophrenia]
    A V Smulevich
    Zh Nevrol Psikhiatr Im S S Korsakova 103:4-13. 2003
    ..Its induced by antipsychotics and combine with extrapyramidal disorders...
  27. ncbi Psychosis in Parkinson's disease
    Werner Poewe
    Department of Neurology, University of Innsbruck, Innsbruck, Austria
    Mov Disord 18:S80-7. 2003
    ..Cholinesterase inhibitors may prove an additional option in psychotic PD patients with dementia...
  28. ncbi Kynurenic acid and schizophrenia
    Sophie Erhardt
    Dept of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Adv Exp Med Biol 527:155-65. 2003
    ..The present study suggests a contribution of KYNA in the pathogenesis of schizophrenia and link the dopamine hypothesis of schizophrenia together with the idea of a deficiency of glutamate function in this disease...
  29. ncbi Safety and efficacy of long-acting risperidone in schizophrenia: a 12-week, multicenter, open-label study in stable patients switched from typical and atypical oral antipsychotics
    Jean Pierre Lindenmayer
    Manhattan Psychiatric Center, New York University School of Medicine, New York, NY 10035, USA
    J Clin Psychiatry 65:1084-9. 2004
    ..The safety and efficacy of the first long-acting injectable atypical antipsychotic, risperidone, were assessed in stable patients with schizophrenia switched from oral antipsychotic medications...
  30. ncbi A 4-week, double-blind comparison of olanzapine with haloperidol in the treatment of amphetamine psychosis
    Thawatchai Leelahanaj
    Department of Psychiatry and Neurology, Phramongkutklao Hospital, Bangkok, Thiland
    J Med Assoc Thai 88:S43-52. 2005
    ..To compare the efficacy and tolerability of olanzapines and haloperidol in treating patients with amphetamine psychosis...
  31. ncbi Long-term follow-up (24 months) of quetiapine treatment in drug-induced Parkinson disease psychosis
    Colin Klein
    Department of Neurology, Assaf Harofeh Medical Center, Zerifin, Sackler School of Medicine, Tel Aviv University, Israel
    Clin Neuropharmacol 29:215-9. 2006
    ..To evaluate the long-term outcome of quetiapine (QTP) use for drug-induced psychosis in Parkinson disease as assessed by the primary caregiver using the Clinical Global Impression Scale...
  32. ncbi Drug-induced psychosis associated with crystalline methamphetamine
    Glenys Dore
    Macquarie Hospital, Sydney, NSW, Australia
    Australas Psychiatry 14:86-9. 2006
    ..A case of drug-induced psychosis related to crystalline methamphetamine is described, highlighting the phenomenology and relevant treatment...
  33. ncbi Improvement or worsening of psychotic symptoms after treatment with low doses of aripiprazole
    Michele Raja
    Servizio Psichiatrico di Diagnosi e Cura, Ospedale Santo Spirito, Rome, Italy
    Int J Neuropsychopharmacol 10:107-10. 2007
    ..Conversely, the effectiveness on negative symptoms seem consistent both in patients with or without antipsychotic response. A low dose may be indicated at the beginning of treatment to assess the kind of response...
  34. ncbi HIV-associated medical, behavioral, and psychiatric characteristics of treatment-seeking, methamphetamine-dependent men who have sex with men
    James A Peck
    Friends Research Institute, Los Angeles, CA, USA
    J Addict Dis 24:115-32. 2005
    ....
  35. ncbi ["Usual" cannabis abuse producing an unusual incident]
    H J Heppner
    Klinikum Nurnberg Nord, Medizinische Klinik 2, Intensivmedizin Toxikologie, Lehrstuhl Innere Medizin V Geriatrie, FAU Erlangen Nürnberg
    Dtsch Med Wochenschr 132:560-2. 2007
    ..Except for regular abuse of cannabis there was no medical history of note. He had a sinus tachycardia (130 bpm), a slow pupillary reflex, bilateral hyposphagma and subcutaneous emphysema around the neck and shoulders...
  36. ncbi [Schizoid psychosis during cannabis intake (case report)]
    Peter Gaszner
    Orszagos Pszichiatriai es Neurologiai Intezet, Klinikai Pszichofarmakológiai, Osztálya
    Neuropsychopharmacol Hung 6:90-2. 2004
    ..Marihuana is working on the dopamine system and may cause schizoid psychosis, sometimes permanent psychosis. Cannabis, this light drug might not be a "safe" agent...
  37. ncbi Hospital separations for cannabis- and methamphetamine-related psychotic episodes in Australia
    Louisa Degenhardt
    National Drug and Alcohol Research Centre, University of New South Wales, Sydney, NSW, Australia
    Med J Aust 186:342-5. 2007
    ..To examine trends in hospital separations related to "drug-induced" psychosis for cannabis and methamphetamine, in the context of patterns of cannabis and methamphetamine use in the Australian population...
  38. ncbi A comparison of symptoms and family history in schizophrenia with and without prior cannabis use: implications for the concept of cannabis psychosis
    J Boydell
    Division of Psychological Medicine, PO Box 63, Institute of Psychiatry, De Crespigny Park, Denmark Hill, London, SE5 8AF, United Kingdom
    Schizophr Res 93:203-10. 2007
    ....
  39. ncbi Clinical profiles, scope and general findings of the Western Sydney First Episode Psychosis Project
    Anthony Harris
    University of Sydney, Westmead Hospital, New South Wales, Australia
    Aust N Z J Psychiatry 39:36-43. 2005
    ..To examine the clinical profile, treatment and social functioning of a community-based sample of young people presenting with their first episode of psychosis...
  40. ncbi Risperidone-induced rabbit syndrome in mood disorder
    Ibrahim Eren
    Department of Psychiatry, Suleyman Demirel University, Cunur, Isparta 32260, Turkey
    Eur Psychiatry 19:452-3. 2004
  41. ncbi Clozapine and typical antipsychotics
    David E Ross
    Am J Psychiatry 161:1925-6. 2004
  42. ncbi Do NMDA receptor antagonist models of schizophrenia predict the clinical efficacy of antipsychotic drugs?
    Charles H Large
    Psychiatry CEDD, GlaxoSmithKline, Via Fleming 4, 37135 Verona, Italy
    J Psychopharmacol 21:283-301. 2007
    ....
  43. ncbi Treatment of drug-induced psychosis in Parkinson's disease with ziprasidone can induce severe dose-dependent off-periods and pathological laughing
    Jan Schindehütte
    Paracelsus Elena Klinik Kassel, Klinikstrasse 16, 34128 Kassel, Germany
    Clin Neurol Neurosurg 109:188-91. 2007
    ..Two patients developed pathological laughing as a possible side-effect of ziprasidone. Ziprasidone may serve as an additional "atypical anti-psychotic" for the treatment of DP in PD but can also induce deterioration of motor function...
  44. ncbi Advanced pediatric psychopharmacology
    Jose Vito
    Division of Child and Adolescent Psychiatry, State University of New York, Brooklyn, New York, USA
    J Child Adolesc Psychopharmacol 16:498-502. 2006
  45. pmc Modelling prefrontal cortex deficits in schizophrenia: implications for treatment
    J A Pratt
    PsyRING Psychiatric Research Institute of Neuroscience in Glasgow, West Medical Building, University of Glasgow, Glasgow, UK
    Br J Pharmacol 153:S465-70. 2008
    ..As such it is likely to be a valuable translational model for understanding the neurobiological mechanisms underlying hypofrontality and for identifying and validating novel drug targets that may restore PFC deficits in schizophrenia...
  46. ncbi [Minocycline as a therapeutic drug for methamphetamine use disorders]
    Kenji Hashimoto
    Division of Clinical Neuroscience, Chiba University Center for Forensic Mental Health, 1 8 1 Inohana, Chiba, 260 8670 Japan
    Nihon Shinkei Seishin Yakurigaku Zasshi 28:19-22. 2008
    ..In this review, we discuss minocycline as a new potential therapeutic drug for schizophrenia as well as psychosis associated with these abused drugs...
  47. ncbi [Basic and clinical studies on methampetamine-related psychosis]
    Mitsumoto Sato
    Seishin Shinkeigaku Zasshi 104:179-90. 2002
  48. ncbi Risk factors for treatment-resistive methamphetamine psychosis
    Daryl Fujii
    J Neuropsychiatry Clin Neurosci 14:239-40. 2002
  49. ncbi Therapeutic tolerance and rebound psychosis during quetiapine maintenance monotherapy in patients with schizophrenia and schizoaffective disorder
    Howard C Margolese
    Clinical Psychopharmacology Unit, Allan Memorial Institute, McGill University Health Centre, Montreal, Quebec, Canada
    J Clin Psychopharmacol 22:347-52. 2002
    ..Seeman and Tallerico3 have proposed pharmacologic explanations for quetiapine and clozapine drug-induced rebound phenomena...
  50. ncbi Cannabis use and brain structural alterations in first episode schizophrenia--a region of interest, voxel based morphometric study
    Srihari S Bangalore
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA, 15213 USA
    Schizophr Res 99:1-6. 2008
    ..The results suggest that cannabis use may be associated with altered brain structure, in particular regions rich in CB1 receptors. These findings need to be confirmed by larger, prospective studies...
  51. ncbi Familial predisposition for psychiatric disorder: comparison of subjects treated for cannabis-induced psychosis and schizophrenia
    Mikkel Arendt
    Centre for Psychiatric Research, Aarhus University Hospital, Skovagervej 2, Risskov, 8240 Risskov, Denmark
    Arch Gen Psychiatry 65:1269-74. 2008
    ..Cannabis-induced psychosis is considered a distinct clinical entity in the existing psychiatric diagnostic systems. However, the validity of the diagnosis is uncertain...
  52. ncbi [Ziprasidone in Parkinsonian dopamine psychosis]
    E Duran-Ferreras
    Servicio de Neurologia, Hospital Universitario Virgen Macarena, 41003 Sevilla, Espana
    Rev Neurol 46:476-80. 2008
    ..In this work, we examine the role that ziprasidone (ZPS) can play in PDP...
  53. ncbi Use of quetiapine in elderly patients
    Pierre N Tariot
    Department of Psychiatry, University of Rochester School of Medicine, Monroe Community Hospital, Rochester, NY 14620, USA
    J Clin Psychiatry 63:21-6. 2002
    ....
  54. ncbi Cannabis and psychiatric disorders: it is not only addiction
    F Markus Leweke
    Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany
    Addict Biol 13:264-75. 2008
    ..With numerous open questions and controversial results, further research is required to specify and extend the findings in this area, which provides a promising target for novel pharmacotherapeutic interventions...
  55. ncbi [Levodopa dependency in Parkinson's disease: case report and review]
    U Muller
    Klinik und Poliklinik fur Psychiatrie, Universitat Leipzig, Germany
    Nervenarzt 73:887-91. 2002
    ....
  56. ncbi Cabergoline-induced psychotic exacerbation in schizophrenic patients
    Shen Chieh Chang
    Department of Psychiatry, Taipei Medical University Wan Fang Medical Center, Taipei, Taiwan
    Gen Hosp Psychiatry 30:378-80. 2008
    ..Hyperprolactinemia is a well-recognized side effect of antipsychotic treatment. Cabergoline, a dopamine agonist, has been introduced on the market to treat hyperprolactinemia, even secondary to antipsychotic use...
  57. pmc Is the incidence of psychotic disorder in decline? Epidemiological evidence from two decades of research
    J B Kirkbride
    Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Int J Epidemiol 38:1255-64. 2009
    ..We had the opportunity to determine whether incidence had changed over a 20-year period in a single setting, and test whether this could be explained by demographic or clinical changes...
  58. ncbi Sources of diagnostic uncertainty for chronically psychotic cocaine abusers
    A Shaner
    West Los Angeles Veterans Affairs Medical Center, CA, USA
    Psychiatr Serv 49:684-90. 1998
    ..This study determined the sources and frequency of diagnostic uncertainty for patients with chronic psychosis and active cocaine abuse or dependence and assessed the usefulness of prospective follow-up in clarifying diagnosis...
  59. ncbi Management of psychotic aspects of Parkinson's disease
    J L Juncos
    Emory University School of Medicine Movement Disorders Program and the Wesley Woods Center of Aging, Atlanta, GA 30329, USA
    J Clin Psychiatry 60:42-53. 1999
    ....
  60. ncbi Comments on the paper 'The effect of a herbal medicine (Mao-to) for the prevention of interferon-induced psychiatric complications in chronic hepatitis C: a pilot study'
    Jennifer M Loftis
    Hum Psychopharmacol 20:211-2; author reply 213. 2005
  61. ncbi Cannabis use and psychotic disorders: an update
    Wayne Hall
    Office of Public Policy and Ethics, Institute for Molecular Bioscience University of Queensland Australia
    Drug Alcohol Rev 23:433-43. 2004
    ..It seems more likely that cannabis use can precipitate schizophrenia in vulnerable individuals. There is also reasonable evidence for the third hypothesis that cannabis use exacerbates psychosis...
  62. ncbi Polar hysteria: an expression of hypervitaminosis A
    James O'Donnell
    Department of Pharmacology, Rush University Medical Center, Chicago, Illinois, USA
    Am J Ther 11:507-16. 2004
    ....
  63. ncbi [An auto-iatrogenic disease]
    W H Reinhart
    Medizinische Klinik, Kantonsspital, Chur
    Ther Umsch 61:715-9. 2004
    ..This case illustrates the dangers of self-treatment by doctors and the difficulties in treating a physician...
  64. ncbi Development of subtle psychotic symptoms with memantine: a case report
    Edward D Huey
    J Clin Psychiatry 66:658-9. 2005
  65. pmc Drug induced autoenucleation with resultant chiasmal damage
    Richard K Imes
    Br J Ophthalmol 89:783. 2005
  66. ncbi Combined intoxication with methylone and 5-MeO-MIPT
    Eiji Shimizu
    Department of Integrative Neurophysiology, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuouku, Chiba 260 8670, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 31:288-91. 2007
    ..This case report suggests that clinicians should be alert to the possibility of the emergence of methylone or 5-MeO-MIPT intoxication, and substance-related mental disorder may be complicated by combined use of other psychoactive drugs...
  67. ncbi Recovery of neuropsychological functions during reduction in use of phencyclidine
    J Cosgrove
    California School of Professional Psychology, Fresno 93721
    J Clin Psychol 47:159-69. 1991
    ..Analysis of each variable revealed that substantial improvement occurred on the acquisition, recall, and delayed recall scores of the Randt Memory Test. Improvement also was noted for some individuals on Trails B and Digit Symbol tests...
  68. ncbi Remoxipride, a selective dopamine D2 receptor antagonist, in tardive dyskinesia
    U Andersson
    Psychiatric Research Center, University of Uppsala, Sweden
    Psychopharmacology (Berl) 94:167-71. 1988
    ..It is concluded that remoxipride in the dose range used has anti-dyskinetic effects but does not induce parkinsonism...
  69. ncbi Psychotic patients who become worse on neuroleptics
    M B Bowers
    Yale University School of Medicine, Department of Psychiatry, New Haven, Connecticut 06519
    J Clin Psychopharmacol 8:417-21. 1988
    ..We propose that some patients with affective psychoses are uniquely susceptible to profound blockade of the nigrostriatal dopaminergic system by neuroleptics...
  70. ncbi Admission of Parkinsonian patients to a neurological ward in a community hospital
    Colin Klein
    Department of Neurology, Assaf Harofeh Medical Center, Zerifin, Sackler Faculty Medicine, Tel Aviv University, Tel Aviv, Israel
    J Neural Transm 116:1509-12. 2009
    ..After analyzing our results, we instituted an "open door" policy, where patients are free to come to the Parkinson's clinic without appointment. This policy should improve control of PD symptoms and diminish hospitalizations...
  71. pmc Adverse reaction to mefloquine associated with ethanol ingestion
    R C Wittes
    Division of Infectious Disease, Ottawa Civic Hospital, Ont
    CMAJ 152:515-7. 1995
    ..It is hypothesized that the combination of MFQ and ethanol caused the two episodes of severe psychiatric disturbance...
  72. ncbi Combating psychosis in Parkinson's disease patients: the use of antipsychotic drugs
    Kelvin L Chou
    Department of Clinical Neurosciences, Brown Medical School, Providence, Rhode Island, USA
    Expert Opin Investig Drugs 15:339-49. 2006
    ....
  73. ncbi Use of khat and posttraumatic stress disorder as risk factors for psychotic symptoms: a study of Somali combatants
    Michael Odenwald
    University of Konstanz, Konstanz, Germany
    Soc Sci Med 69:1040-8. 2009
    ..However, the proposed causal chain needs to be confirmed in longitudinal studies. Demobilization and reintegration programs in Somalia need to be prepared to deal with complex psychological problems...
  74. ncbi [Rethinking criminal responsibility: practical application of operational diagnosis and gnostic into expert testimony]
    Takayuki Okada
    National Center of Neurology and Psychiatry, Institute of Mental Health, Department of Forensic Psychiatry
    Seishin Shinkeigaku Zasshi 107:920-35. 2005
    ..The authors also discussed various topics related to criminal responsibility including Asperger's syndrome, illicit drug intoxication, and prescribed drug intoxication...
  75. ncbi [Significance of historical and current hallucinogenic research in psychiatry]
    L Hermle
    Fachkrankenhaus für Psychiatrie und Neurologie, Christophsbad, Goppingen
    Nervenarzt 64:562-71. 1993
    ..It is argued that from a systematic as well as from a methodological viewpoint the traditional approach of experimental psychosis represents a valuable tool in psychiatric research...
  76. ncbi [Neurotoxicity secondary to ifosfamide manifesting as psychosis and comma]
    J A Valdueza Beneitez
    Farm Hosp 30:315-6. 2006
  77. ncbi The endocannabinoid system as a target for modelling psychosis
    Dagmar Koethe
    Central Institute of Mental Health, Ruprecht Karls University Heidelberg, Mannheim, Germany
    Psychopharmacology (Berl) 206:551-61. 2009
    ..These "altered states of consciousness" provide a long-standing and valid approach to enhance our understanding of certain aspects of schizophrenia...
  78. ncbi Khat chewing: an emerging drug concern in Australia?
    Johana Stefan
    Aust N Z J Psychiatry 39:842-3. 2005
  79. ncbi Genetic variants of D2 but not D3 or D4 dopamine receptor gene are associated with rapid onset and poor prognosis of methamphetamine psychosis
    Hiroshi Ujike
    Department of Neuropsychiatry, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
    Prog Neuropsychopharmacol Biol Psychiatry 33:625-9. 2009
    ..00037, OR=3.62, 95% CI 2.48-5.28). These findings revealed that genetic variants of DRD2, but not DRD3 or DRD4, confer individual risks for rapid onset, prolonged duration, and spontaneous relapse of methamphetamine psychosis...
  80. ncbi A polymorphism of DRD2 gene and brain atrophy in methamphetamine psychosis
    M Harano
    Department of Neuropsychiatry, Kurume University School of Medicine, Kurume, Fukuoka, Japan
    Ann N Y Acad Sci 1025:307-15. 2004
    ..It is suggested that in methamphetamine psychosis the TaqI A polymorphism not only regulates prolongation of psychosis symptoms but also influences the form of the temporal lobe...
  81. ncbi GABA-ergic neurons and the neurobiology of schizophrenia and other psychoses
    E B Keverne
    Sub Department of Animal Behaviour, University of Cambridge, UK
    Brain Res Bull 48:467-73. 1999
    ..These interneurons have highly divergent inhibitory projections to large numbers of pyramidal neurons and are themselves synchronised by the ascending dopamine and serotonin innervations...
  82. ncbi [Experimental animal models of psychoses]
    V Dauge
    Encephale 29:S12-5. 2003
  83. ncbi Acute psychosis associated with levetiracetam
    Sotiris Youroukos
    First Department of Paediatrics, Athens University Medical School, St Sophia Children s Hospital, Athens, Greece
    Epileptic Disord 5:117-9. 2003
    ..The psychotic behavior resolved completely soon after the discontinuation of levetiracetam...
  84. pmc Visual scan paths in first-episode schizophrenia and cannabis-induced psychosis
    Philip J Benson
    College of Life Sciences and Medicine, King s College, University of Aberdeen, UK
    J Psychiatry Neurosci 32:267-74. 2007
    ..We used higher-order statistical methods to examine spatiotemporal characteristics of scan paths to determine whether viewing behaviour was distinguishable on a continuum...
  85. ncbi Case report: an ingestion of Hawaiian Baby Woodrose seeds associated with acute psychosis
    Jeffrey H Gertsch
    University of Hawaii, John A Burns School of Medicine, Department of Psychiatry, University Tower, 4th Floor, 1356 Lusitana Street, Honolulu, Hawaii 96813, USA
    Hawaii Med J 62:127, 129. 2003
    ....
  86. ncbi [Probable levetiracetam-induced psychosis]
    Joan Roig
    Med Clin (Barc) 129:278. 2007
  87. ncbi Ketamine associated psychedelic effects and dependence
    D K Lim
    Department of Adult Psychiatry Unit 3, Woodbridge Hospital, Singapore 539747
    Singapore Med J 44:31-4. 2003
    ..The detection of ketamine abuse requires a high index of suspicion and needs to be considered when there is an acute presentation with multi-modal hallucinations and psychosis...
  88. ncbi The importance of being seizure free: topiramate and psychopathology in epilepsy
    Marco Mula
    Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, UK
    Epilepsy Behav 4:430-4. 2003
    ..We observed that psychopathology was related to seizure control in a subgroup of patients. The role of forced normalization, interlinked with interactions with other antiepileptic drugs, could be relevant...
  89. ncbi Analysis of association of clinical correlates and 5-HTTLPR polymorphism with suicidal behavior among Chinese methamphetamine abusers
    Chih Ken Chen
    Department of Psychiatry, Chang Gung Memorial Hospital, Keelung, Taiwan
    Psychiatry Clin Neurosci 61:479-86. 2007
    ....
  90. ncbi Corticosteroids, immune suppression, and psychosis
    Dana C Perantie
    Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9070, USA
    Curr Psychiatry Rep 4:171-6. 2002
    ..However, the role of the immune system in mediating the psychiatric disturbances with each of these conditions is not clear. Directions for further research and treatment considerations are discussed...
  91. ncbi Effect of bilateral subthalamic nucleus stimulation on levodopa-unresponsive axial symptoms in Parkinson's disease
    K Yamada
    Department of Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    Acta Neurochir (Wien) 150:15-22; discussion 22. 2008
    ..We retrospectively investigated the effects of bilateral STN stimulation on the axial signs unresponsive to levodopa in Japanese patients with PD...
  92. ncbi The effect of quetiapine on psychosis and motor function in parkinsonian patients with and without dementia
    Sujana Reddy
    Department of Psychiatry, Albany Medical Center, Albany, New York 12205, USA
    Mov Disord 17:676-81. 2002
    ..We conclude that quetiapine is effective in improving psychosis in approximately 80% of PD patients both with and without dementia. Patients with dementia seem to have a higher propensity for worsening of motor symptoms...
  93. ncbi Six months follow-up of patients with methamphetamine psychosis
    H S Yeh
    Department of Psychiatry, Taipei Veterans General Hospital, 201, Sec 2, Shih Pai Road, Taipei 112, Taiwan
    Zhonghua Yi Xue Za Zhi (Taipei) 64:388-94. 2001
    ..Some authors preferred MAP psychosis model of schizophrenia, while other studies found difference between the two groups of patients in the aspects of negative symptoms...
  94. pdf Atypical antipsychotics: mechanism of action
    Philip Seeman
    Departments of Pharmacology and Psychiatry, University of Toronto, Toronto, Ontario
    Can J Psychiatry 47:27-38. 2002
    ..To understand how these drugs work, it is important to examine the atypical antipsychotics' mechanism of action and how it differs from that of the more typical drugs...
  95. ncbi Cannabis and psychosis
    John Macleod
    Lancet 370:1539; author reply 1539-40. 2007
  96. ncbi Psychosis associated with prescribed dexamphetamine use
    Jon Spear
    Aust N Z J Psychiatry 37:383. 2003
  97. pmc Mefloquine: contraindicated in patients with mood, psychotic or seizure disorders
    Eric Wooltorton
    CMAJ 167:1147. 2002
  98. ncbi The successful use of electroconvulsive therapy in a patient with interferon-induced psychotic depression
    Miriam Tanja Zincke
    University of Medicine and Dentistry of New Jersey New Jersey Medical School, Newark, NJ 07103, USA
    J ECT 23:291-2. 2007
    ..We reviewed the literature of similar cases and discuss treatment options for interferon-induced depression and psychosis...
  99. ncbi [Usefulness of olanzapine in the levodopa-induced psychosis in patients with Parkinson's disease]
    J R Chacon
    Servicios de Neurologia, Hospital Universitario Virgen Macarena, Sevilla, Spain
    Neurologia 17:7-11. 2002
    ..To evaluate the antipsychotic efficacy of olanzapine (OLZ) in patients with Parkinson's disease (PD) and drug-induced psychosis (DIP) and its repercussion on the motor function...
  100. ncbi Spiperone binding capacity in lymphocytes of patients with alcohol- and drug-induced psychosis: preliminary results
    M Soyka
    Psychiatische Klinik und Poliklinik, , Federal Republic of Germany
    J Stud Alcohol 55:503-7. 1994
    ..Possible implications of these findings for future research are discussed...
  101. ncbi A case of disulfiram-methylphenidate interaction: implications for treatment
    Herve Caci
    Am J Psychiatry 164:1759. 2007

Research Grants41

  1. SERVICE NEEDS IN EARLY PSYCHOSIS AND DRUG USE
    CAROL CATON; Fiscal Year: 2003
    ..Greater knowledge of the long-term course and outcome of these disorders may lead to more appropriate matches to treatment for substance use, and may uncover unmet needs for services. ..
  2. Cannabinoid Receptor Function in Alcoholism: Effects of D-9-THC
    DEEPAK D SOUZA; Fiscal Year: 2008
    ..These results may reflect indirect evidence of altered CB-1R function in FHP individuals. [unreadable] [unreadable] [unreadable]..
  3. Cannabinoids, Neural Synchrony and Information Processing
    DEEPAK D SOUZA; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  4. HIV Risk Among Homeless Mothers
    CAROL CATON; Fiscal Year: 2007
    ..The study will inform the design of HIV risk behavior preventive interventions appropriate to the life circumstances of homeless mothers. ..
  5. DRUG USE AND COURSE OF HOMELESSNESS AMONG SINGLE ADULTS
    CAROL CATON; Fiscal Year: 2003
    ..Greater understanding of factors that determine the course of homelessness has implications for the development of prevention and early intervention strategies. ..
  6. NEUROBIOLOGY OF CANNABIS EFFECTS
    DEEPAK D SOUZA; Fiscal Year: 2009
    ....
  7. GLYCINE-KETAMINE INTERACTIONS IN HEALTHY SUBJECTS
    DEEPAK D SOUZA; Fiscal Year: 2002
    ..Pilot data (n=12) towards this proposal suggests that glycine reduces ketamine-induced perceptual alterations, negative symptoms and impairments on recall without worsening positive symptoms. ..
  8. A Peer Support Intervention for Psychosis and Drug Use
    CAROL CATON; Fiscal Year: 2004
    ..abstract_text> ..
  9. Chinese Exercise Modalites in Parkinson's Disease
    Jorge Juncos; Fiscal Year: 2003
    ..A better understanding of exercise-induced neural plasticity and motor control would offer a significant, and heretofore unexploited rehabilitative potential in PD. ..
  10. Human Genetics of Drug-Abuse Related Phenotypes
    Joseph Cubells; Fiscal Year: 2007
    ..The latter goal will be accomplished by the candidate directing the newly-established Yale Human Behavioral Genetics Clinic, which offers psychiatric and substance-abuse services to patients with genetic illnesses. ..
  11. Flumazenil on Multiple Stress and Withdrawal Anxiety
    George Breese; Fiscal Year: 2007
    ....
  12. Serotonin Club IUPHAR Satellite Meeting
    Mark Geyer; Fiscal Year: 2006
    ..Hence, helping neuroscientists-in-training attend the meeting will have a positive influence on trainees and a lasting impact on the field. [unreadable] [unreadable] [unreadable]..
  13. Symposium on Neuroimaging in Alcoholism
    John Krystal; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  14. Abnormal Eye Movement in Schizophrenia: Genome-Wide Scan
    Randal Ross; Fiscal Year: 2008
    ..Linkage in both groups will assessed using methods capable of detecting genetic effects on quantitative traits. ..
  15. Childhood Physiology and Risk for Schizophrenia
    Randal Ross; Fiscal Year: 2008
    ..Clarification of this methodology may lead to a novel prenatal intervention strategy designed to decrease risk for adolescent and adult onset of psychosis. ..
  16. Neural Correlates of Methamphetamine Use in Schizophrenia: An MRS Study
    Ruth Salo; Fiscal Year: 2007
    ..These findings will have important implications for neurobiological models of comorbid substance abuse and treatment. [unreadable] [unreadable] [unreadable]..
  17. Prospective Study: Alcoholic & Control Family Offspring
    Marc A Schuckit; Fiscal Year: 2010
    ..Our ultimate goal is to identify ways to prevent the escalation of drinking and associated problems in young populations. ..
  18. Stress Sensitization of CRF-Induced Withdrawal Behaviors
    George Breese; Fiscal Year: 2009
    ..New treatment strategies could emerge from such knowledge ..
  19. Genetics of plasma dopamine beta-hydroxylase activity in schizophrenia
    Joseph Cubells; Fiscal Year: 2009
    ..Identifying predictors of varying outcomes in SCZ would open new avenues for development of targeted interventions that could significantly ameliorate the impact of SCZ on individuals and society. ..
  20. DEVELOPMENTAL MODELS OF GATING DEFICITS IN SCHIZOPHRENIA
    Mark A Geyer; Fiscal Year: 2010
    ..Hence, Aim 3 studies will test the hypothesized differential roles of specific CRF receptors in mediating isolation rearing-induced deficits in PPI in mice, using CRF-R1 and CRF-R2 null mutant mice. ..
  21. LEVEL OF RESPONSE TO ALCOHOL AND BRAIN FUNCTIONING
    Marc A Schuckit; Fiscal Year: 2010
    ..The project will also expand our understanding of the neural substrates of the level of response to alcohol, a key risk factor for the development of alcohol dependence. ..
  22. Novel Glutamatergic Detoxification Strategies
    John Krystal; Fiscal Year: 2006
    ..abstract_text> ..
  23. Naltrexone for Bipolar Disorder and Alcohol Dependence
    E Sherwood Brown; Fiscal Year: 2006
    ..Alcohol use is the primary outcome, and alcohol craving is the secondary outcome. Manic and depressive symptom severity and the relationship between changes in alcohol use and changes in mood will be expIored. ..
  24. MOLECULAR BIOLOGY OF ETHANOL ACTION ON RECEPTORS
    George Breese; Fiscal Year: 2002
    ..Further, based upon structural analysis of ethanol's action on protein-protein inter-actions for the receptors, results may ultimately allow us to predict other protein-protein interactions influenced by ethanol. ..
  25. Symposium on Neuroimaging in Alcoholism
    John Krystal; Fiscal Year: 2003
    ..A call for abstracts also will bring forward names and ideas from other groups that might be added to the main program. Young Investigator travel scholarships will be considered. ..
  26. AMINO ACID NEUROTRANSMITTER DYSREGULATION IN ALCOHOLISM
    John Krystal; Fiscal Year: 2003
    ..In summary, this K02 award would foster my academic development and enable me to better contribute to the building of pathophysiologic models of alcoholism that can guide medications development for this disorder. ..
  27. EMERGENCY PHYSICIAN BRIEF INTERVENTIONS FOR ALCOHOL
    GAIL D ONOFRIO; Fiscal Year: 2003
    ..abstract_text> ..
  28. Treating Asthma Patients with Major Depressive Disorder
    E Sherwood Brown; Fiscal Year: 2004
    ....
  29. BEHAVIORAL THERAPY FOR DEPRESSION IN DRUG DEPENDENCE
    Edward Nunes; Fiscal Year: 2002
    ..3. To test the theory that an increase in response-contingent reinforcement will produce an improvement in depression and reduced drug use. ..
  30. NEUROSTEROIDS IN THE ACTION OF ETHANOL ON GABA
    George Breese; Fiscal Year: 2004
    ..Completion of the Aims will allow critical new information to emerge concerning the molecular basis of neurosteroid action on GABAA receptor function that allows ethanol to enhance GABA function in vitro. ..
  31. HIPPOCAMPAL FUNCTION DURING CORTICOSTEROID THERAPY
    E Sherwood Brown; Fiscal Year: 2004
    ..Through this award, the Pl will extend his previous research experience by adding new skills and knowledge which will be used for investigations at the interface of neuroscience and clinical research. ..
  32. White Matter Integrity in Familial Schizophrenia
    Lynn DeLisi; Fiscal Year: 2006
    ..Since this hypothesis has not been tested specifically in this way and is speculative, but if correct, may have a great impact on future research, we are using the R21 exploratory mechanism. ..
  33. Behavioral Therapy Development for Methamphetamine Abuse
    James Peck; Fiscal Year: 2005
    ..Effectiveness data from this research will be used to inform the continued Stage II development of this intervention. ..
  34. DRUG ABUSE PHARMACOTHERAPY: METHODOLOGIC INITIATIVES
    Edward Nunes; Fiscal Year: 2005
    ..The applicant will continue to pursue a training plan focused on methodology and statistics of clinical trials, behavioral interventions, and the responsible conduct of research. ..
  35. Cognitive Sequelae of Methamphetamine Abuse
    Ruth Salo; Fiscal Year: 2005
    ..abstract_text> ..
  36. NASD Yale New Haven Hospital Emergency Department 2004
    GAIL D ONOFRIO; Fiscal Year: 2004
    ..abstract_text> ..
  37. Perinatal Vulnerability to Psychosis
    Randal Ross; Fiscal Year: 2004
    ....
  38. NALTREXONE BLOCKADE OF NMDA
    John Krystal; Fiscal Year: 2002
    ..Thus, the blockade of the rewarding effects of ketamine by naltrexone may provide insight into an important mechanism underlying the psychopharmacology of ethanol and the treatment of alcoholism. ..
  39. AMINO ACID NEUROTRANSMITTER DYSREGULATION IN ALCOHOLISM
    John Krystal; Fiscal Year: 2008
    ..abstract_text> ..
  40. Enhancing EP-Performed Alcohol Interventions in the ED
    GAIL D ONOFRIO; Fiscal Year: 2009
    ..abstract_text> ..
  41. STARTLE GATING AND LOCOMOTION IN D2-FAMILY KNOCKOUT MICE
    Mark Geyer; Fiscal Year: 2004
    ..This information will have important implications for the further development of therapeutic approaches to the treatment of both schizophrenia and drug abuse. ..