Genomes and Genes
Summary: Poisoning occurring after exposure to cadmium compounds or fumes. It may cause gastrointestinal syndromes, anemia, or pneumonitis.
Publications178 found, 100 shown here
- Reversal of cadmium induced oxidative stress by chelating agent, antioxidant or their combination in ratS K Tandon
Chemical Toxicology, Industrial Toxicology Research Center, Post Box 80, Lucknow 226001, India
Toxicol Lett 145:211-7. 2003..The results suggest that the administration of an antioxidant during chelation of cadmium may provide beneficial effects by reducing oxidative stress without its cadmium removing ability...
- [Cadmium]Masahiko Satoh
Department of Hygienics, Gifu Pharmaceutical University
Nihon Rinsho 62:334-8. 2004
- Plant science: the key to preventing slow cadmium poisoningStephan Clemens
Department of Plant Physiology, University of Bayreuth, 95440 Bayreuth, Germany
Trends Plant Sci 18:92-9. 2013..The emerging molecular understanding of Cd uptake, root retention, root-to-shoot translocation and grain loading will enable the development of low Cd-accumulating crops...
- Cadmium toxicity revisited: focus on oxidative stress induction and interactions with zinc and magnesiumVesna Matovic
Department of Toxicology Akademik Danilo Soldatović, Faculty of Pharmacy, University of Belgrade, Serbia
Arh Hig Rada Toksikol 62:65-76. 2011..At present, there is no clinically efficient agent to treat cadmium poisoning due to predominantly intracellular location of cadmium ions...
- Histopathological alterations in the edible snail, Babylonia areolata (spotted babylon), in acute and subchronic cadmium poisoningP Tanhan
Department of Biology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
Environ Toxicol 20:142-9. 2005..The epithelial lining of the digestive tract showed similar alterations such as increased size of mucous vacuoles, reduced length of cilia, and dilation of nuclei. In addition, fragmentation of the muscle sheath was observed...
- Melatonin abrogates cadmium induced oxidative stress related neurotoxicity in ratsK Shagirtha
Department of Biochemistry and Biotechnology, Faculty of Science, Annamalai University, Annamalainagar, India
Eur Rev Med Pharmacol Sci 15:1039-50. 2011....
- Dietary cadmium exposure and prostate cancer incidence: a population-based prospective cohort studyB Julin
Unit of Nutritional Epidemiology, The Institute of Environmental Medicine, Karolinska Institutet, Box 210, 171 77 Stockholm, Sweden
Br J Cancer 107:895-900. 2012..Experimental data convincingly propose the toxic metal cadmium as a prostate carcinogen. Cadmium is widely dispersed into the environment and, consequently, food is contaminated...
- Striking association between urinary cadmium level and albuminuria among Torres Strait Islander people with diabetesMelissa Haswell-Elkins
North Queensland Health Equalities Promotion Unit, School of Medicine, University of Queensland, Cairns, QLD 4870, Australia
Environ Res 106:379-83. 2008..This study explored associations between albuminuria and an index of cadmium exposure (urinary cadmium excretion) in the presence and absence of Type 2 diabetes...
- Serum vasoactive agents in rats poisoned with cadmiumHelena Martynowicz
Department of Internal Medicine, Occupational Diseases and Hypertension, Wrocław Medical University, Poland
Int J Occup Med Environ Health 17:479-85. 2004..The aim of this study was to evaluate the impact of subchronic Cd poisoning on blood nitric oxide or endothelin in blood and to relate it to the redox system activity in vessel walls and to blood Cd concentration...
- [Acute and chronic cadmium poisoning]P Andujar
INSERM, Unité 955, 94000 Creteil, France
Rev Med Interne 31:107-15. 2010..According to literature, no chelating agent can be still used in human cadmium poisonings. In France, some diseases caused by occupational exposure to cadmium may be compensated...
- Renal organic cation transporters mediated cadmium-induced nephrotoxicitySunhapas Soodvilai
Department of Physiology, Faculty of Science, Mahidol University, Rama VI Road, Rajathevi, Bangkok, Thailand
Toxicol Lett 204:38-42. 2011..Taken together, this study provides for the first time, evidence showing OCT1 and OCT2 mediating cadmium transport across the basolateral membrane into the renal proximal tubular cells...
- The impact of subchronic cadmium poisoning on the vascular effect of nitric oxide in ratsA Skoczynska
Department of Internal Medicine, Occupational Diseases and Hypertension, Wroclaw Medical University, L Pasteur 4, Wroclaw, Poland
Hum Exp Toxicol 24:353-61. 2005..05) in both groups of cadmium-treated rats. These results suggest that cadmium in hypertensive doses modifies the vascular effect of NO in basal conditions and after stimulation by ACh...
- Captopril and telmisartan treatments attenuate cadmium-induced testicular toxicity in ratsAmr A Fouad
Department of Biomedical Sciences, Pharmacology Division, College of Medicine, King Faisal University, Al Ahsa, Saudi Arabia
Fundam Clin Pharmacol 27:152-60. 2013..The differences between the results obtained with captopril and telmisartan were insignificant, suggesting that both drugs equally protected the testicular tissue from the detrimental effects of cadmium...
- Effect of glutathione on the cadmium chelation of EDTA in a patient with cadmium intoxicationHyo Wook Gil
Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, 23 20 Bongmyung dong, Cheonan City, South Korea
Hum Exp Toxicol 30:79-83. 2011..These results suggest that glutathione administration with EDTA might be an effective treatment modality for patients with cadmium intoxication...
- Relationship among prevalence of patients with Itai-itai disease, prevalence of abnormal urinary findings, and cadmium concentrations in rice of individual hamlets in the Jinzu River basin, Toyama prefecture of JapanTakeshi Ogawa
Department of Occupational and Environmental Medicine, Graduate School of Medicine, Chiba University, Japan
Int J Environ Health Res 14:243-52. 2004..This study demonstrated that Itai-itai disease is induced by exposure to environmental Cd and that renal dysfunction plays an important role in its development...
- Dietary cadmium and risk of invasive postmenopausal breast cancer in the VITAL cohortScott V Adams
Fred Hutchinson Cancer Research Center, Cancer Prevention Program, 1100 Fairview Ave N, Seattle, WA 98109, USA
Cancer Causes Control 23:845-54. 2012..The aim of the study was to estimate the association between dietary intake of cadmium, a carcinogenic heavy metal, and risk of invasive postmenopausal breast cancer...
- Cadmium, osteoporosis and calcium metabolismGeorge Kazantzis
Department of Environmental Science and Technology, Imperial College London, UK
Biometals 17:493-8. 2004..The identification of cadmium, an environmental pollutant, as one causal factor is highly significant in helping to control the incidence of this complex condition...
- Cadmium therapeutic agentsC Kelley
Department of Chemistry, Northern Arizona University, Flagstaff, AZ 86011 5698
Curr Pharm Des 5:229-40. 1999..Preliminary attempts to combat acute cadmium poisoning included the use of the chelating agents ethylenediaminetetraacetic acid (EDTA) and British anti-Lewisite (..
- Low dose cadmium poisoning results in sustained ERK phosphorylation and caspase activationPatrick Martin
Transcriptional Regulation and Differentiation, CNRS UMR 6548, Nice University, Parc Valrose, 06108 Nice Cedex 2, France
Biochem Biophys Res Commun 350:803-7. 2006b>Cadmium poisoning has been known to result in a wide variety of cellular responses, including oxidative stress and kinase activation...
- Influence of drinking and/or cooking with Jinzu River water on the development of Itai-itai diseaseEtsuko Kobayashi
Department of Occupational and Environmental Medicine A2, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuohku, Chiba, Japan
Biol Trace Elem Res 129:46-57. 2009....
- The vascular endothelium as a target of cadmium toxicityWalter C Prozialeck
Department of Pharmacology, Midwestern University, 555 31st Street, Downers Grove, IL 60515, United States
Life Sci 79:1493-506. 2006..In addition the possible roles of the vascular endothelium in mediating the tumor promoting and anticarcinogenic effects of Cd are discussed...
- Mortality in a cadmium polluted area in JapanMuneko Nishijo
Department of Public Health, Kanazawa Medical University, Uchinada, Ishikawa, Japan
Biometals 17:535-8. 2004....
- Male infertility and environmental exposure to lead and cadmiumS Benoff
Department of Obstetrics and Gynecology, North Shore University Hospital New York University School of Medicine, Manhasset 11032, USA
Hum Reprod Update 6:107-21. 2000..Reverse transcriptase-polymerase chain reaction assays for Ca2+ and K+ channel isoforms may identify susceptibility subgroups with lower resistance to environmental exposures...
- Influence of consumption of cadmium-polluted rice or Jinzu River water on occurrence of renal tubular dysfunction and/or Itai-itai diseaseEtsuko Kobayashi
Department of Occupational and Environmental Medicine, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuohku, Chiba 260 8670, Japan
Biol Trace Elem Res 127:257-68. 2009....
- Cadmium exposure aggravates mortality more in women than in menMirei Uetani
Department of Occupational and Environmental Medicine, Graduate School of Medicine, Chiba University, Chiba, Japan
Int J Environ Health Res 16:273-9. 2006..This study revealed that Cd exposure aggravates mortality more in women than in men...
- Acute cadmium chloride administration induces hepatic and renal CYP2A5 mRNA, protein and activity in the mouse: involvement of transcription factor NRF2A edah Abu-Bakar
National Research Centre for Environmental Toxicology, University of Queensland, 39 Kessels Road, Coopers Plains, 4108 Qld, Brisbane, Australia
Toxicol Lett 148:199-210. 2004..Upregulation of CYP2A5 by cadmium in the Nrf2 +/+ mice but not in the Nrf2-/- mice indicates a role for this transcription factor in the regulation...
- Experimental reproduction of itai-itai disease, a chronic cadmium poisoning of humans, in rats and monkeysT Umemura
Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo, Japan
Jpn J Vet Res 48:15-28. 2000....
- Potential for early involvement of CYP isoforms in aspects of human cadmium toxicityJason R Baker
National Research Center for Environmental Toxicology, University of Queensland, 39 Kessels Road, Coopers Plains, QLD 4108, Brisbane, Australia
Toxicol Lett 137:85-93. 2003..Potential mechanisms by which Cd may alter CYP4A11 expression are discussed briefly...
- [Concentration of cadmium in breast cancer tissue of women living in the Wielkopoiska region]Anna Rydzewska
Pracownia Ochrony Srodowiska, Katedry Biologii i Ochrony Srodowiska, Akademia Medyczna im K Marcinkowskiego, Poznaniu
Przegl Lek 61:786-8. 2004..Moreover, marked differences were observed between the average cadmium concentrations in the breast cancer tissue samples in women living in the remaining voivodships and the types of living areas...
- Cadmium and health in the 21st century--historical remarks and trends for the futureGunnar F Nordberg
Environmental Medicine, Department of Public Health and Clinical Medicine, Umea University, SE 90187 Umea, Sweden
Biometals 17:485-9. 2004..In many countries, Cd exposures are now under better control than in the past. The target for the 21st century is to achieve a totally acceptable exposure situation without adverse health effects from Cd...
- Influence of vitamin C on cadmium absorption and distribution in ratsAndrzej Grosicki
Laboratory of Radiological Protection and Isotopic Research, National Veterinary Research Institute, ul Partyzantow 57, 24 100 Pulawy, Poland
J Trace Elem Med Biol 18:183-7. 2004..In addition, the rats supplemented with vitamin C revealed an improved body weight gain during the experimental period...
- [The effects on bone of environmental cadmium exposure--summary of recent epidemiological studies]Ikiko Tsuritani
Department of Hygiene, Kanazawa Medical University, Japan
Clin Calcium 14:45-50. 2004..The effect on bone could be caused indirectly through renal damage induced by cadmium exposure, or directly via an effect of cadmium on bone itself...
- Effect of environmental exposure to cadmium on pregnancy outcome and fetal growth: a study on healthy pregnant women in ChinaYa Li Zhang
Department of Biology, Institute of Radiation Medicine, Chinese Academy of Medical Sciences, Tianjin, China
J Environ Sci Health A Tox Hazard Subst Environ Eng 39:2507-15. 2004..24cm decrease in neonatal birth height. There was no significant association between cadmium exposure and birth weight. It was concluded that environmental exposure to cadmium significantly lower neonatal birth height...
- Cytotoxic mechanisms of Zn2+ and Cd2+ involve Na+/H+ exchanger (NHE) activation by ROSSophia Koutsogiannaki
Laboratory of Animal Physiology, Zoology Department, School of Biology, Faculty of Science, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece
Aquat Toxicol 78:315-24. 2006..In addition, differences between the two metals concerning NHE activation, O2- production and interaction with adrenergic receptors were observed...
- Urinary excretion of cadmium among Torres Strait Islanders (Australia) at risk of elevated dietary exposure through traditional foodsMelissa Haswell-Elkins
North Queensland Health Equalities Promotion Unit, School of Population Health, University of Queensland, Cairns, Queensland, Australia
J Expo Sci Environ Epidemiol 17:372-7. 2007..This study highlights the need to consider social and cultural variation in exposure and to define "safe" cadmium levels during diabetes given its rising global prevalence...
- Tissue cadmium (Cd) concentrations of people living in a Cd polluted area, JapanMirei Uetani
Department of Occupational and Environmental Medicine, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chiba, 260 8670, Japan
Biometals 19:521-5. 2006....
- Trace mineral profile in blood and hair from cattle environmentally exposed to lead and cadmium around different industrial unitsR C Patra
Environmental Medicine Laboratory, Division of Medicine, Indian Veterinary Research Institute, Izatnagar 243 122, UP, India
J Vet Med A Physiol Pathol Clin Med 53:511-7. 2006..385, 0.643) concentrations. Thus, it is concluded from the present study that the higher blood lead concentrations in cattle irrespective of locality/industrial operations areas affected trace elements profile in blood and hair...
- Anthropometric, environmental, and dietary predictors of elevated blood cadmium levels in Ukrainian children: Ukraine ELSPAC groupLee S Friedman
Division of Environmental and Occupational Health Sciences, School of Public Health, University of Illinois, Chicago, IL, 60612, USA
Environ Res 102:83-9. 2006..Whole-blood cadmium levels observed in this group of Ukrainian children appear to be similar to those reported in other Eastern European countries...
- The effects of combined alpha-tocopherol, ascorbic acid, and selenium against cadmium toxicity in rat intestineSehnaz Bolkent
Department of Biology, Faculty of Science, Istanbul University, Vezneciler, Istanbul, Turkey
J Environ Pathol Toxicol Oncol 26:21-7. 2007..As a result, the combination of ascorbic acid, alpha-tocopherol, and selenium shows a protective effect against cadmium toxicity in small intestine...
- Renal dysfunction of cadmium-exposed workers residing in a cadmium-polluted environmentTaiyi Jin
Department of Occupational Health, School of Public Health, Fudan University 200032 Shanghai, PR China
Biometals 17:513-8. 2004..Furthermore, health examinations of this population should be conducted in time to prevent further health damage induced by cadmium exposure...
- Biochemical effects of lead, zinc, and cadmium from mining on fish in the Tri-States District of northeastern Oklahoma, USAChristopher J Schmitt
U S Geological Survey, Columbia Environmental Research Center, 4200 New Haven Road, Columbia, Missouri 65201, USA
Environ Toxicol Chem 24:1483-95. 2005..Collectively, our results indicate that Pb is both bioavailable and active biochemically in the Spring-Neosho River system...
- The threshold cadmium level that causes a substantial increase in beta2-microglobulin in urine of general populationsMasayuki Ikeda
Kyoto Industrial Health Association, Kyoto, Japan
Tohoku J Exp Med 205:247-61. 2005..Thus, it is concluded that there is a threshold Cd-Ucr level that leads to a substantial increase in beta2-MG-Ucr, and that the threshold level is greater than 4 microg/g cr...
- Statement concerning the situation in the Wenzhou areaBaochu Lin
Wenzhou Anti Epidemic Station, Wenzhou, Zhejiang, PR China
Biometals 17:595. 2004
- Markers of cadmium exposure in workers in a cadmium pigment factory after changes in the exposure conditionsTakashi Kawasaki
Department of Hygiene and Public Health, Osaka Medical College, Osaka, Japan
Toxicol Ind Health 20:51-6. 2004..Reversibility of urinary low molecular weight protein was observed in the workers over the four years...
- Importance of metallothioneins in the cadmium detoxification process in Daphnia magnaB Fraysse
Laboratoire d Eco toxicologie, EA 2069 URVVC, Faculte des Sciences, Université de Reims Champagne Ardenne Moulin de la Housse BP 1039, 51687 Reims Cedex2, France
Comp Biochem Physiol C Toxicol Pharmacol 144:286-93. 2006..Monitoring sub-cellular distribution of metals after exposure in the natural environment could be very useful for ecotoxicological assessment...
- Effect of the flavonoid quercetin on cadmium-induced hepatotoxicityC Vicente-Sánchez
Instituto Reina Sofia de Investigacion Nefrologica, Departamento de Fisiologia y Farmacologia, Universidad de Salamanca, Spain
Food Chem Toxicol 46:2279-87. 2008..These results suggest that other mechanisms different to oxidative stress could be involved in hepatic damage...
- The potential role of combined anti-oxidants against cadmium toxicity on liver of ratsMeral Koyuturk
Department of Histology and Embryology, Faculty of Medicine, Istanbul Science University, 34394 Esentepe, Istanbul, Turkey
Toxicol Ind Health 23:393-401. 2007..As a result, these results suggest that combined anti-oxidants treatment might be useful in protection of liver against Cd toxicity...
- Estimation of cumulative cadmium intake causing Itai-itai diseaseTakeya Inaba
Department of Occupational and Environmental Medicine, Graduate School of Medicine A2, Chiba University, Japan
Toxicol Lett 159:192-201. 2005..6 and 3.3 g, respectively. The present results clarify that Itai-itai disease, the most severe stage of chronic Cd poisoning, occurs at levels of Cd consumption amounting to approximately three-fold of those currently seen in Japan...
- Interactions between metabolism of trace metals and xenobiotic agonists of the aryl hydrocarbon receptor in the antarctic fish Trematomus bernacchii: environmental perspectivesFrancesco Regoli
Istituto di Biologia e Genetica, Universita Politecnica delle Marche, Ancona, Italy
Environ Toxicol Chem 24:1475-82. 2005....
- Environmental epidemiological study and estimation of benchmark dose for renal dysfunction in a cadmium-polluted area in ChinaTaiyi Jin
Department of Occupational Health, School of Public Health, Fudan University, Shanghai, 200032 Shanghai, PR China
Biometals 17:525-30. 2004..This report is the first to use the BMD method in this field and to define the concept of critical concentration in urine...
- Renal dysfunction induced by cadmium: biomarkers of critical effectsAlfred Bernard
Catholic University of Louvain, 1200 Brussels, Belgium
Biometals 17:519-23. 2004..Cd-induced microproteinuria is usually considered as irreversible except at the incipient stage of the intoxication where a partial or complete reversibility has been found in some studies...
- Influence of cadmium and zinc on the mice resistance to Listeria monocytogenes infectionSandrita Simonyte
Institute for Biomedical Research, Kaunas University of Medicine, 3007 Kaunas, Lithuania
Medicina (Kaunas) 39:767-72. 2003..The objective of this study was to examine the effect of chronic exposure to cadmium and zinc on the mice resistance to experimental Listeria monocytogenes infection...
- No clear-cut evidence for cadmium-induced renal tubular dysfunction among over 10,000 women in the Japanese general population: a nationwide large-scale surveyT Ezaki
Kyoto Industrial Health Association, 67 Nishinokyo Kitatsuboicho, Nakagyo ku, Kyoto 604 8472, Japan
Int Arch Occup Environ Health 76:186-96. 2003..To examine whether environmental exposure to cadmium has been inducing kidney dysfunction among middle-aged women in the general population in Japan...
- Determinants of cadmium burden levels in a population of children living in the vicinity of nonferrous smeltersA Leroyer
, Lille, 59037, France
Environ Res 87:147-59. 2001..14; 95% CI=[1.07-1.21] and x 1.25; 95% CI=[1.04-1.50]. Neither sex nor age was associated with CdB. Mean CdU was associated with paternal occupational cadmium exposure...
- Cadmium nephrotoxicity and evacuation from the body in a rat modeled subchronic intoxicationTeiichiro Aoyagi
Department of Urology, Ichikawa General Hospital, Tokyo Dental College, Ichikawa, Japan
Int J Urol 10:332-8. 2003..We studied Cd-induced subchronic nephrotoxicity and the cadmium evacuation system in rats and cultured human renal tubular cells...
- A retrospective study on the relation between renal dysfunction and cadmium concentration in rice in individual hamlets in the Jinzu River basin, Toyama Prefecture, JapanT Osawa
Department of Hygiene, Chiba University School of Medicine, Chiba, 260-8670, Japan
Environ Res 86:51-9. 2001..The allowable values of Cd concentration in rice were estimated to be in the range of 0.05-0.20 ppm, representing values lower than the 0.4 ppm provisionally adopted by the Japanese government...
- Role of S-adenosyl-L-methionine in potentiating cadmium mobilization by diethylenetriamine penta acetic acid in miceU Gubrelay
School of Studies in Zoology, Jiwaji University, Gwalior, India
Cytobios 104:99-105. 2001..The treatment with SAM alone was also effective in correcting the zinc and GSH concentrations. The results indicated few beneficial effects of concomitant SAM administration during chelation of cadmium with DTPA...
- [Biological function of some elements and their compounds. III. Zinc--component and activator of enzymes]Helena Puzanowska-Tarasiewicz
Department of Chemistry Sciences, Higher School of Cosmetology and Protection of Health, Bialystok, Poland
Pol Merkur Lekarski 27:419-22. 2009..Zinc acts protectively in lead and cadmium poisoning and it participates in the elimination of free superoxide radicals (it inhibits of oxygenation of non-..
- Long-term extracellular signal-related kinase activation following cadmium intoxication is negatively regulated by a protein kinase C-dependent pathway affecting cadmium transportPatrick Martin
CNRS FRE3094, Universite de Nice Sophia Antipolis, Nice, France
FEBS J 276:1667-79. 2009..Our results indicate that PKC activation negatively affects ZIP8 transporter activity, thus protecting cells against cadmium poisoning.
- Dimercaptosuccinic acid (DMSA), a non-toxic, water-soluble treatment for heavy metal toxicityA L Miller
Alternative Medicine Review P O Box 25, Dover, ID 83825, USA
Altern Med Rev 3:199-207. 1998..Cases of severe acute lead, mercury, arsenic, and cadmium poisoning are rare; however, when they do occur an effective, non-toxic treatment is essential...
- Effect of cadmium-polluted water on plasma levels of tumor necrosis factor-α, interleukin-6 and oxidative status biomarkers in rats: protective effect of curcuminAbdullah Alghasham
Department of Pharmacology and Therapeutics, College of Medicine, Qassim University, Saudi Arabia
Food Chem Toxicol 59:160-4. 2013..Negative correlation between IL-6 or TNF-α was and the plasma activities of catalase, SOD and the level of total antioxidant capacity were found in rats exposed to Cd...
- A global perspective on cadmium pollution and toxicity in non-occupationally exposed populationSoisungwan Satarug
National Research Centre for Environmental Toxicology, University of Queensland, 39 Kessels Road, Coopers Plains, QLD 4108, Brisbane, Australia
Toxicol Lett 137:65-83. 2003..Increased mortality was found among individuals showing signs of cadmium renal toxicity compared with those without such signs, suggesting that renal toxicity may be an early warning of complications, sub-clinical or clinical morbidity...
- Influence of time period of cadmium intoxication on the concentrations of ascorbic acid selenium in certain tissues and blood serum of ratsKazimierz Pasternak
Department of General Chemistry, Medical University of Lublin
Ann Univ Mariae Curie Sklodowska Med 57:132-7. 2002..Furthermore, it has been demonstrated that ascorbic acid and selenium concentrations are dependent on the type of tissue tested as well as on the size of cadmium concentrations and length of the experiments...
- Pb and Cd poisoning during development alters cerebellar and striatal function in ratsM Teresa Antonio
Department of Animal Biology II, Faculty of Biology, Complutense University, 20840, Madrid, Spain
Toxicology 176:59-66. 2002..to examine more fully the neurochemical and behavioral interactions that derive from continued lead and cadmium poisoning in pups, whose mothers were exposed via drinking water (300 mg/l of Pb and 10 mg/l of Cd) throughout ..
- Effect of chronic administration of cadmium on the rat thyroid: radioimmunological and immunohistochemical studiesB Piłat-Marcinkiewicz
Department of Histology and Embryology, Medical Academy, Białystok, Poland
Folia Histochem Cytobiol 40:189-90. 2002..Serum T3 concentration was not affected by Cd, while T4 was reduced but only at the exposure to the higher Cd concentration. Moreover, the rats exposed to Cd showed a decrease in serum Ca concentration...
- Cadmium distribution and metallothionein expression in lizard tissues following acute and chronic cadmium intoxicationFrancesca Trinchella
Dipartimento delle Scienze Biologiche Sezione di Biologia Evolutiva e Comparata, Universita Federico II, Via Mezzocannone 8, 80134 Napoli, Italy
Comp Biochem Physiol C Toxicol Pharmacol 144:272-8. 2006..Following a dietary cadmium treatment, a positive correlation between the increase of metallothionein mRNA and cadmium accumulation is found in intestine, ovary and kidney, while no correlation is present in liver and brain...
- The German Environmental Survey 1990/92 (GerES II): primary predictors of blood cadmium levels in adultsK Hoffmann
Institute for Water, Soil and Air Hygiene, Federal Environmental Agency, Berlin, Germany
Arch Environ Health 56:374-9. 2001..In this model, the effect of smoking was considered, and the model accounted for the biological half-life of cadmium in blood...
- Estimation of benchmark doses for urinary cadmium based on beta2-microglobulin excretion in cadmium-polluted regions of the Kakehashi River basin, JapanAkane Shimizu
Department of Occupational and Environmental Medicine, Graduate School of Medicine A2, Chiba University, Chiba, Japan
Int J Environ Health Res 16:329-37. 2006....
- Intravenous 1alpha, 25[OH]2 vitamin D3 (calcitriol) pulse therapy for bone lesions in a murine model of chronic cadmium toxicosisY Kurata
Toxicology Division, Mitsubishi Chemical Safety Institute Ltd, Ibaraki, Japan
Int J Exp Pathol 82:43-53. 2001..The findings indicated that the increased osteoid volume of the cortex and Fe-deposition volume of the trabecula were improved. These effects or improvements were observed in the sham-OVX rats but not in the OVX rats...
- Protective effects of glutathione and lipoic acid against cadmium-induced oxidative stress in rat's kidneyAndrej R Veljkovic
Faculty of Medicine, University of Nis, Nis, Serbia
Ren Fail 34:1281-7. 2012..The increased level of TBARS and the increased activity of XO in kidney tissue in cadmium poisoning are statistically significant compared to control (p < 0.001)...
- Association between cadmium concentration in rice and mortality in the Jinzu River basin, JapanT Ishihara
Department of Hygiene, Chiba University School of Medicine, 1 8 1 Inohana, Chuohku, 260 8670, Chiba, Japan
Toxicology 163:23-8. 2001....
- Preliminary immunohistochemical study of C cells of the thyroid and endocrine cells of the parathyroid glands in rats after prolonged exposure to cadmiumB Piłat-Marcinkiewicz
Department of Histology and Embryology, Medical Academy, Białystok, Poland
Folia Histochem Cytobiol 39:191-2. 2001..The animals exposed to cadmium showed attenuation of all reactions, which was most distinct after 50 mg Cd/dm3. Exposure-dependent cadmium accumulation and a decrease in calcium concentration in the femoral bone were noted...
- [Exposure of the Berlin population to aromatic hydrocarbons and heavy metals within the scope of a study of the health effects of vehicular traffic]H Fromme
Institut für Umweltanalytik und Humantoxikologie, Berlin
Gesundheitswesen 59:512-8. 1997..A statistical connection of benzene in blood to the indoor air concentration or the to the average daily traffic density could not be seen, but there is a relation to smoking habits...
- [Dosage of cadmium and lead in human blood by anodic stripping voltammetry]Tarik Attar
Laboratoire d Electrochimie et Chimie Analytique, Departement de Chimie, Faculte des Sciences, Université Abou Bekr Belkaid, Tlemcen, Algerie
Ann Biol Clin (Paris) 70:595-8. 2012..The obtained limits of detection are equal to 0.46 and 0.08 ng/mL respectively for the lead and the cadmium. The developed method was validated by the analysis of reference materials certified by total blood...
- Changes in the structure and function of the kidney of rats chronically exposed to cadmium. II. Histoenzymatic studiesMałgorzata M Brzóska
Department of Toxicology, Medical University of Białystok, Mickiewicza 2c, 15 222 Białystok, Poland
Arch Toxicol 78:226-31. 2004..The results, together with observations reported in the first paper of the study, incline us to conclude that humans environmentally exposed to Cd are at risk of tubular damage...
- Chronic cadmium treatment induces islet B cell injury in ovariectomized cynomolgus monkeysYoshimasa Kurata
Laboratory of Comparative Pathology, Department of Veterinary Clinical Sciences, Graduate School of Veterinary Medicine, Hokkaido University, Sapporo 060 0818, Japan
Jpn J Vet Res 50:175-83. 2003..Therefore the islet B cell is one of the major targets of the chronic Cd poisoning in monkeys...
- Immunohistochemical and ultrastructural changes in the renal cortex of cadmium-treated ratsMevlut Asar
Department of Histology and Embryology, Faculty of Medicine, University of Akdeniz, Antalya, Turkey
Biol Trace Elem Res 97:249-63. 2004..In conclusion, cadmium toxicity results in alterations in the renal extracellular matrix and tubular or glomerular cells, which could play an important role in renal dysfunction...
- Cadmium affects the social behaviour of rainbow trout, Oncorhynchus mykissKatherine A Sloman
Department of Biological Sciences, Brunel University, Uxbridge, Middlesex UB8 3PH, UK
Aquat Toxicol 65:171-85. 2003....
- The effects of a vitamin D-deficient diet on chronic cadmium exposure in ratsHideomi Uchida
Kumamoto Laboratory, Toxicological Science Division, Medi Chem Business Segment, Mitsubishi Chemical Medience Corporation, Kumamoto 869 0425, Japan
Toxicol Pathol 38:730-7. 2010..The present experiment demonstrated that hypovitaminosis D did not evoke morphologic features of IID in humans but did enhance Cd-induced toxicity in the rat model of this disease...
- Synthesis and spectroscopic and structural studies of a new cadmium(II)-citrate aqueous complex. Potential relevance to cadmium(II)-citrate speciation and links to cadmium toxicityM Dakanali
Department of Chemistry, University of Crete, Heraklion 71409, Greece
Inorg Chem 42:2531-7. 2003....
- Bias induced by the use of creatinine-corrected values in evaluation of beta2-microgloblin levelsM Ikeda
Kyoto Industrial Health Association, 67 Nishinokyo Kitatsuboicho, Nakagyo ku, 604 8472, Kyoto, Japan
Toxicol Lett 145:197-207. 2003....
- Changes in antioxidant status and biochemical parameters after orally cadmium administration in females ratsS Chater
Laboratoire de Physiologie Integree, Faculte des Sciences de Bizerte, 7021 Jarzouna, Tunisia
Acta Biol Hung 60:79-88. 2009..05). Results showed that cadmium given to dams led to an oxidative stress and DNA damage in tissues of pregnant rats...
- In utero exposure to cadmium pollution in Cairo and Giza governorates of EgyptG Mokhtar
Department of Paediatrics, Ain Shams University, Cairo, Egypt
East Mediterr Health J 8:254-60. 2002..The cadmium levels did not differ between subjects from Cairo and Giza or according to urban, suburban or rural areas. Thus, in utero exposure to cadmium was evident and wider-scale studies on its long-term effects are recommended...
- Evaluation of metallothionein as a biomarker of single and combined Cd/Cu exposure in Dreissena polymorphaS Lecoeur
UMR INRA DGER Métabolisme et Toxicologie Comparés des Xénobiotiques, Ecole NationaleVétérinaire de Lyon, 1, av Bourgelat, BP 83, F 69280 Marcy l Etoile, France
Environ Res 94:184-91. 2004..Our results suggest that the form of MT existing in D. polymorpha was not Cu-inducible. This could limit the use of MT in D. polymorpha as a biomarker of heavy metal pollution in freshwater ecosystems...
- Latest status of cadmium accumulation and its effects on kidneys, bone, and erythropoiesis in inhabitants of the formerly cadmium-polluted Jinzu River Basin in Toyama, Japan, after restoration of rice paddiesHyogo Horiguchi
Division of Environmental Medicine, Center for Community Medicine, Jichi Medical University, 3311 1 Yakushiji, Shimotsuke, Tochigi, 329 0498, Japan
Int Arch Occup Environ Health 83:953-70. 2010..The aim of this study is to investigate whether inhabitants there would still exhibit cadmium accumulation and its effects on kidneys, bones, and erythropoiesis...
- Attenuation of cadmium-induced necrotic cell death by necrostatin-1: potential necrostatin-1 acting sitesTzu Sheng Hsu
Institute of Molecular and Cellular Biology and Department of Life Science, National Tsing Hua University, Hsinchu, Taiwan
Toxicol Appl Pharmacol 235:153-62. 2009..Our study shows that, in addition to DR-mediated necrosis, Nec-1 is effective in attenuating Cd-induced necrosis. It rescues cells with reduced MMP implying that mitochondrion is its major acting site...
- Gut microbiota limits heavy metals burden caused by chronic oral exposureJerome Breton
Bactéries Lactiques and Immunité des Muqueuses, Centre d Infection et d Immunité de Lille, Institut Pasteur de Lille, INSERM U 1019, CNRS UMR 8204 Université Lille Nord de France, 1 rue du Pr Calmette, BP 245, F 59019 Lille, France
Toxicol Lett 222:132-8. 2013..Collectively, these data illustrate the complex host-microbes interplay occurring with environmental pollutants inside the gut. ..
- Protective effects of quercetin on cadmium-induced cytotoxicity in primary cultures of rat proximal tubular cellsLin Wang
College of Animal Science and Veterinary Medicine, Shandong Agricultural University, Taian 271018, Shandong, China
Biomed Environ Sci 26:258-67. 2013..To investigate the protective effects of quercetin on cadmium-induced cytotoxicity in primary cultures of rat proximal tubular (rPT) cells...
- The liver in itai-itai disease (chronic cadmium poisoning): pathological features and metallothionein expressionHayato Baba
Department of Diagnostic Pathology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan
Mod Pathol 26:1228-34. 2013..Prolonged exposure to low doses of Cd leads to high hepatic accumulation, which can then cause fibrosis; however, it also causes high expression of metallothionein, which is thought to reduce Cd hepatotoxicity...
- [Investigation of health status of workers exposed to low concentration cadmium in a zinc powder factory]Yu Lian Zhang
Changsha Municipal Center for Disease Control and Prevention, Changsha 410001, China
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 29:936-8. 2011..To explore the health status of workers exposed to Cd at low concentration...
- Effects of chronic cadmium poisoning on Zn, Cu, Fe, Ca, and metallothionein in liver and kidney of ratsDing Zhang
College of Veterinary Medicine, Huazhong Agricultural University, Wuhan 430070, People s Republic of China
Biol Trace Elem Res 149:57-63. 2012An experiment was conducted to invest effects of chronic cadmium poisoning on Zn, Cu, Fe, Ca, and metallothionein gene expression and protein synthesis in liver and kidney in rats...
- Prior cadmium exposure improves glucoregulation in diabetic rats but exacerbates effects on metabolic dysregulation, oxidative stress, and hepatic and renal toxicityPrem Kumar Singh
Division of Metabolic Endocrinology, Department of Zoology, Faculty of Science, The M S University of Baroda, Vadodara 390002, Gujarat, India
Drug Chem Toxicol 35:167-77. 2012..Overall, the present results are novel and interesting to open more investigations on animal models of type 1 diabetes with a history of previous Cd exposure...
- [The effect of lead and cadmium on the lipid profile and psychosocial functioning of children with developmental disorders]Małgorzata Szkup-Jabłońska
Samodzielna Pracownia Propedeutyki Pielegniarstwa Pomorskiego Uniwersytetu Medycznego w Szczecinie ul Zołnierska 48, 71 210 Szczecin
Ann Acad Med Stetin 57:69-77. 2011..The aim of this study was to examine the relationship between the concentration of lead, cadmium, and polyunsaturated fatty acids, and functioning of the child with developmental disorders...
- Bradykinin potentiating factor isolated from Buthus occitanus venom has a protective effect against cadmium-induced rat liver and kidney damageSouad H M Bekheet
Zoology Department, Faculty of Science, Aswan, South Valley University, Egypt
Tissue Cell 43:337-43. 2011....
- Comparative effects of repeated administration of cadmium chloride during pregnancy and lactation and selenium protection against cadmium toxicity on some organs in immature rats' offspringsSouad H M Bekheet
Zoology Department, Faculty of Science, South Valley University, Aswan, Egypt
Biol Trace Elem Res 144:1008-23. 2011....
- A polymorphism in metallothionein 1A (MT1A) is associated with cadmium-related excretion of urinary beta 2-microglobulinLijian Lei
Department of Occupational Health, School of Public Health, Fudan University, Shanghai, China
Toxicol Appl Pharmacol 265:373-9. 2012..In humans Cd is mainly bound to metallothioneins (MT), which scavenge its toxic effects. Here we analyzed whether polymorphisms in MT genes MT1A and MT2A influence Cd-related kidney damage...
- Oxidative damage in liver after perinatal intoxication with lead and/or cadmiumElvira Luján Massó
Department of Animal Physiology II, Biology College, Complutense University of Madrid, Madrid, Spain
J Trace Elem Med Biol 21:210-6. 2007..Finally, simultaneous perinatal administration of both metals seems to protect, at least, in the liver TBARS production against the toxicity produced by Cd or Pb separately...
- Strong poison revisitedRoger C Prince
ExxonMobil Biomedical Sciences Inc, 1545 Route 22 East, Annandale, NJ 08801, USA
J Inorg Biochem 101:1891-3. 2007....
- Individual susceptibility to cadmium toxicity and metallothionein gene polymorphisms: with references to current status of occupational cadmium exposureNobuhiko Miura
National Institute of Occupational Safety and Health, 6 21 1 Nagao, Tama ku, Kawasaki 214 8585, Japan
Ind Health 47:487-94. 2009..This article describes the strategy method for analyzing individual susceptibility to cadmium toxicity and genetic polymorphisms of metallothionein, with reference to the current status of occupational cadmium exposure...
- [Effects of cadmium on testis function]Helena Martynowicz
Katedry i Kliniki Chorób Wewnetrznych, Zawodowych i Nadciśnienia Tętniczego, Akademii Medycznej we Wrocławiu
Med Pr 56:167-74. 2005..Increasing environmental exposure to cadmium, currently existing occupational exposure and the prevalence of tobacco smoking results in constant increase in the number of diagnosed fertility impairments...
- Cadmium toxicity on arterioles vascular smooth muscle cells of spontaneously hypertensive ratsBENNY WASHINGTON
Department of Biological Sciences, Tennessee State University, Nashville, TN 37209, USA
Int J Environ Res Public Health 3:323-8. 2006..The present studies support the hypothesis that Cd can be a risk factor of hypertension through dysfunction of vascular smooth muscle cells under certain conditions...
- Annual SMRU Traveling Scholar ConferenceSusan Benoff; Fiscal Year: 2005..Without this exposure, many of them would have likely pursued different career paths. ..
- Core Surveillance of Occupatiional Health in New YorkKITTY GELBERG; Fiscal Year: 2004..Health (BOH) has operated a Heavy Metals Registry for the reporting of cases of lead, mercury, arsenic, and cadmium poisoning, and an Occupational Lung Disease Registry for the reporting of cases of work related lung disease...
- MECHANISMS OF CADMIUM TOXICITY IN EPITHELIAL CELLSWALTER PROZIALECK; Fiscal Year: 2007..Furthermore, the results of these studies could have more general implications regarding the mechanisms by which toxic substances affect living organisms. ..
- INCREASED TESTICULAR CD2+ & INFERTILITY WITH VARICOCELESusan Benoff; Fiscal Year: 2004..Controls will include fertile donors and fertile men with varicocele. ..
- HUMAN SPERM ZONA ACCEPTOR: ENVIRONMENTAL EFFECTSSusan Benoff; Fiscal Year: 2005..Outcome is test of hypothesis, and possible mechanism explaining infertility associated with low sperm counts or idiopathic male infertility, tools for diagnosis, and hope for treatment. ..
- Annual SMRU Traveling Scholars ConferenceSusan Benoff; Fiscal Year: 2006..Without this exposure, many of them would have likely pursued different career paths. [unreadable] [unreadable] [unreadable] [unreadable]..