intussusception

Summary

Summary: A form of intestinal obstruction caused by the PROLAPSE of a part of the intestine into the adjoining intestinal lumen. There are four types: colic, involving segments of the LARGE INTESTINE; enteric, involving only the SMALL INTESTINE; ileocecal, in which the ILEOCECAL VALVE prolapses into the CECUM, drawing the ILEUM along with it; and ileocolic, in which the ileum prolapses through the ileocecal valve into the COLON.

Top Publications

  1. ncbi Evaluation of anatomic changes in young children with natural rotavirus infection: is intussusception biologically plausible?
    Christine G Robinson
    Pediatric Clinical Research Office, Nashville, Tennessee 37232, USA
    J Infect Dis 189:1382-7. 2004
  2. ncbi Intussusception risk and health benefits of rotavirus vaccination in Mexico and Brazil
    Manish M Patel
    Centers for Disease Control and Prevention, 1600 Clifton Rd, MS A 47, Atlanta, GA 30333, USA
    N Engl J Med 364:2283-92. 2011
  3. ncbi Intussusception following rotavirus vaccine administration: post-marketing surveillance in the National Immunization Program in Australia
    J P Buttery
    SAEFVIC in Child and Adolescent Immunisation, Murdoch Children s Research Institute, Parkville, Victoria 3052, Australia
    Vaccine 29:3061-6. 2011
  4. ncbi Research priorities regarding rotavirus vaccine and intussusception: a meeting summary
    Jacqueline E Tate
    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Vaccine 30:A179-84. 2012
  5. ncbi Two year review of intestinal intussusception in six large public hospitals of Santiago, Chile
    Miguel O'Ryan
    Microbiology Program, Instituto de Ciencias Biomedicas, Faculty of Medicine, University of Chile, Independencia 1027, Santiago, Chile
    Pediatr Infect Dis J 22:717-21. 2003
  6. ncbi Incidence of rotavirus diarrhea and intussusception in Hong Kong using standardized hospital discharge data
    E A S Nelson
    Department of Paediatrics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, People s Republic of China
    Pediatr Infect Dis J 21:701-3. 2002
  7. pmc Ileocolic intussusception due to a cecal endometriosis: case report and review of literature
    Rivkine Emmanuel
    Department of Digestive and Endocrine Surgery, University Hospital Jean Verdier, Assistance Publique Hopitaux de Paris, Avenue du 14 Juillet, 93140 Bondy, Paris, France
    Diagn Pathol 7:62. 2012
  8. ncbi Postmarketing surveillance of intussusception following mass introduction of the attenuated human rotavirus vaccine in Mexico
    F Raul Velazquez
    Medical Research Unit on Infectious Diseases, Pediatrics Hospital, National Medical Center Century XXI, Mexican Institute of Social Security IMSS, Mexico City, Mexico
    Pediatr Infect Dis J 31:736-44. 2012
  9. pmc Intussusception of the bowel in adults: a review
    Athanasios Marinis
    Second Department of Surgery, Areteion University Hospital, Athens Medical School, University of Athens, 76 Vassilisis Sofia s Ave, 11528, Athens, Greece
    World J Gastroenterol 15:407-11. 2009
  10. ncbi Sociodemographic and dietary risk factors for natural infant intussusception in the United States
    Brian Johnson
    National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Pediatr Gastroenterol Nutr 51:458-63. 2010

Detail Information

Publications308 found, 100 shown here

  1. ncbi Evaluation of anatomic changes in young children with natural rotavirus infection: is intussusception biologically plausible?
    Christine G Robinson
    Pediatric Clinical Research Office, Nashville, Tennessee 37232, USA
    J Infect Dis 189:1382-7. 2004
    Several studies have shown an association between vaccination with the rotavirus vaccine and the development of intussusception. We evaluated the plausibility of a causal association between natural rotavirus infection and intussusception.
  2. ncbi Intussusception risk and health benefits of rotavirus vaccination in Mexico and Brazil
    Manish M Patel
    Centers for Disease Control and Prevention, 1600 Clifton Rd, MS A 47, Atlanta, GA 30333, USA
    N Engl J Med 364:2283-92. 2011
    Because postlicensure surveillance determined that a previous rotavirus vaccine, RotaShield, caused intussusception in 1 of every 10,000 recipients, we assessed the association of the new monovalent rotavirus vaccine (RV1) with ..
  3. ncbi Intussusception following rotavirus vaccine administration: post-marketing surveillance in the National Immunization Program in Australia
    J P Buttery
    SAEFVIC in Child and Adolescent Immunisation, Murdoch Children s Research Institute, Parkville, Victoria 3052, Australia
    Vaccine 29:3061-6. 2011
    In Australia, post-marketing surveillance for intussusception following vaccination commenced with funding of RotaTeq(®) and Rotarix(®) vaccines under the National Immunization Program (NIP) in July 2007.
  4. ncbi Research priorities regarding rotavirus vaccine and intussusception: a meeting summary
    Jacqueline E Tate
    Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA
    Vaccine 30:A179-84. 2012
    Currently available rotavirus vaccines have been associated with a small increased risk of intussusception (~1-2 cases per 100,000 vaccinated infants) in some populations...
  5. ncbi Two year review of intestinal intussusception in six large public hospitals of Santiago, Chile
    Miguel O'Ryan
    Microbiology Program, Instituto de Ciencias Biomedicas, Faculty of Medicine, University of Chile, Independencia 1027, Santiago, Chile
    Pediatr Infect Dis J 22:717-21. 2003
    A need for updated information on different aspects of idiopathic intussusception resurged after the Rotashield experience...
  6. ncbi Incidence of rotavirus diarrhea and intussusception in Hong Kong using standardized hospital discharge data
    E A S Nelson
    Department of Paediatrics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong SAR, People s Republic of China
    Pediatr Infect Dis J 21:701-3. 2002
    Incidence for rotavirus and intussusception was estimated from standardized discharge data for all Hong Kong government hospitals (1997 to 1999). Intussusception incidence in infants (78 to 100 of 100,000) was relatively high...
  7. pmc Ileocolic intussusception due to a cecal endometriosis: case report and review of literature
    Rivkine Emmanuel
    Department of Digestive and Endocrine Surgery, University Hospital Jean Verdier, Assistance Publique Hopitaux de Paris, Avenue du 14 Juillet, 93140 Bondy, Paris, France
    Diagn Pathol 7:62. 2012
    Cecal endometriosis and ileocolic intussusception due to a cecal endometriosis is extremely rare. We report a case of a woman who presented an ileocecal intussusception due to a cecal endometriosis...
  8. ncbi Postmarketing surveillance of intussusception following mass introduction of the attenuated human rotavirus vaccine in Mexico
    F Raul Velazquez
    Medical Research Unit on Infectious Diseases, Pediatrics Hospital, National Medical Center Century XXI, Mexican Institute of Social Security IMSS, Mexico City, Mexico
    Pediatr Infect Dis J 31:736-44. 2012
    Mexico initiated mass vaccination with the attenuated human rotavirus vaccine (Rotarix) in 2006. This postlicensure study aimed to assess any potential temporal association between vaccination and intussusception in Mexican infants.
  9. pmc Intussusception of the bowel in adults: a review
    Athanasios Marinis
    Second Department of Surgery, Areteion University Hospital, Athens Medical School, University of Athens, 76 Vassilisis Sofia s Ave, 11528, Athens, Greece
    World J Gastroenterol 15:407-11. 2009
    b>Intussusception of the bowel is defined as the telescoping of a proximal segment of the gastrointestinal tract within the lumen of the adjacent segment...
  10. ncbi Sociodemographic and dietary risk factors for natural infant intussusception in the United States
    Brian Johnson
    National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Pediatr Gastroenterol Nutr 51:458-63. 2010
    In 1999, a US case-control study demonstrated a strong association between intussusception and a rotavirus vaccine (Rotashield)...
  11. pmc Intussusception among Japanese children: an epidemiologic study using an administrative database
    Masato Takeuchi
    Department of Pediatrics, The University of Tokyo Hospital, Tokyo, Japan
    BMC Pediatr 12:36. 2012
    The epidemiology of intussusception, including its incidence, can vary between different countries...
  12. ncbi Intussusception: incidence and treatment-insights from the nationwide German surveillance
    Andreas Christoph Jenke
    Children s Hospital, HELIOS Klinikum Wuppertal, Witten Herdecke University, Herdecke, Germany
    J Pediatr Gastroenterol Nutr 52:446-51. 2011
    b>Intussusception (IS) is one of the most common paediatric emergencies, and the best mode of conservative reduction and its exact incidence remains unclear...
  13. ncbi Incidence of intussusception among children 0-5 years of age in Thailand, 2001-2006
    Chowalit Khumjui
    Field Epidemiology Training Program, Bureau of Epidemiology, Department of Disease Control, Ministry of Public Health, Bangkok, Thailand
    Vaccine 27:F116-9. 2009
    To provide baseline incidence data of intussusception among Thai children under 5 years old, outpatient and inpatient records from 2001 to 2006 from five hospitals were reviewed...
  14. ncbi Rotavirus infection and intussusception in Tunisian children: implications for use of attenuated rotavirus vaccines
    Anissa Chouikha
    Research Unit of Virology, UR06 SP20 Laboratory of Microbiology, University Hospital Sahloul, Sousse 4054, Tunisia
    J Pediatr Surg 44:2133-8. 2009
    A licensed rotavirus vaccine was withdrawn from use because of an increased risk of intussusception. The association of rotavirus vaccination with intussusception raised concerns about a potential link between natural rotavirus disease ..
  15. ncbi Predictive factors of malignancy in adults with intussusception
    Brian K P Goh
    Department of Surgery, Singapore General Hospital, Outram Road, Singapore, 169608
    World J Surg 30:1300-4. 2006
    Adult intussusception is an unusual entity, and its etiology differs from that in pediatric patients...
  16. ncbi Risk of intussusception following administration of a pentavalent rotavirus vaccine in US infants
    Irene M Shui
    Department of Epidemiology, Harvard School of Public Health, 677 Huntington Ave, Boston, MA 02115, USA
    JAMA 307:598-604. 2012
    Current rotavirus vaccines were not associated with intussusception in large prelicensure trials...
  17. ncbi Rotavirus disease and its prevention
    Marc Alain Widdowson
    Viral Gastroenteritis Section, Respiratory and Enteric Viruses Branch, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Curr Opin Gastroenterol 21:26-31. 2005
    ..Less than 1 year later, however, the vaccine was withdrawn when reports of cases of intussusception were linked to recent vaccination...
  18. ncbi Acute intussusception in infants and children as an adverse event following immunization: case definition and guidelines of data collection, analysis, and presentation
    Julie E Bines
    Royal Children s Hospital, Parkville, Vic, Australia
    Vaccine 22:569-74. 2004
  19. ncbi Trends in intussusception-associated hospitalizations and deaths among US infants
    U D Parashar
    Viral Gastroenteritis Section, Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, US Department of Health and Human Services, Atlanta, Georgia, USA
    Pediatrics 106:1413-21. 2000
    The newly licensed tetravalent rhesus-human reassortant rotavirus vaccine has been withdrawn following reports of intussusception among vaccinated infants.
  20. pmc Intussusception and rotavirus associated hospitalisation in New Zealand
    Y E Chen
    Christchurch School of Medicine and Health Sciences, Christchurch, New Zealand
    Arch Dis Child 90:1077-81. 2005
    To describe the epidemiology of intussusception and its relation to rotavirus associated hospitalisation in New Zealand.
  21. ncbi Tumor spectrum of adult intussusception
    Jy Ming Chiang
    Division of Colon and Rectal Surgery, Chang Gung Memorial Hospital, 5, Fu Hsing St, Kuei Shan, Tao Yuan corrected Taiwan corrected
    J Surg Oncol 98:444-7. 2008
    Adult intussusception is rare. Most general and colorectal surgeons are unfamiliar with its etiology and optimal management.
  22. ncbi Epidemiology of childhood intussusception and determinants of recurrence and operation: analysis of national health insurance data between 1998 and 2007 in Taiwan
    Solomon Chih Cheng Chen
    Department of Pediatrics, Pingtung Christian Hospital, Pingtung, Taiwan
    Pediatr neonatol 51:285-91. 2010
    To study the epidemiology of childhood intussusception and risk factors of recurrence and operation based on a nationwide data.
  23. ncbi Safety and efficacy of a pentavalent human-bovine (WC3) reassortant rotavirus vaccine
    Timo Vesikari
    University of Tampere Medical School, Tampere, Finland
    N Engl J Med 354:23-33. 2006
    ..Rotavirus is a leading cause of childhood gastroenteritis and death worldwide...
  24. ncbi Changing epidemiology of intussusception in Australia
    Frances Justice
    Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Parkville, Victoria, Australia
    J Paediatr Child Health 41:475-8. 2005
    ..In light of evidence for an association between a rotavirus vaccine and intussusception, it is important to define the baseline epidemiology of intussusception in Australia and establish a system ..
  25. ncbi Adult intussusception: a retrospective review
    Ahmad Zubaidi
    Department of Surgery, Saint Boniface Hospital, Winnipeg, Manitoba, Canada
    Dis Colon Rectum 49:1546-51. 2006
    Whereas intussusception is relatively common in children, it is clinically rare in adults. The condition is usually secondary to a definable lesion...
  26. ncbi Air enema for intussusception: is predicting the outcome important?
    P Ramachandran
    Department of Pediatric Surgery, Kanchi Kamakoti Child s Trust Hospital, 12 A, Nageswara Road, Nungambakkam, Chennai 600034, India
    Pediatr Surg Int 24:311-3. 2008
    ..We retrospectively reviewed the records of 179 children who underwent air enema for intussusception at our institution over a 5-year period...
  27. ncbi Natural rotavirus infection is not associated to intussusception in Mexican children
    F Raul Velazquez
    Unidad de Investigacion Medica en Enfermedades Infecciosas y Parasitarias, Hospital de Pediatria, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico
    Pediatr Infect Dis J 23:S173-8. 2004
    To determine whether natural rotavirus infection or infection by another enteropathogen is associated to intussusception (IS); and to describe the seasonality of IS compared with severe diarrhea (SD) and rotavirus SD in Mexican children.
  28. ncbi Four-country surveillance of intestinal intussusception and diarrhoea in children
    Shally Awasthi
    Department of Paediatrics, King George Medical University, Lucknow, India
    J Paediatr Child Health 45:82-6. 2009
    Establishment of baseline epidemiology of intussusception in developing countries has become a necessity with the possibility of reintroduction of rotavirus vaccine...
  29. ncbi Intussusception in Taiwanese children: analysis of incidence, length of hospitalization and hospital costs in different age groups
    Wan Ling Ho
    Department of Pediatrics, National Taiwan University Hospital, Taipei, Taiwan
    J Formos Med Assoc 104:398-401. 2005
    This study investigated the characteristics of intussusception in Taiwanese children of different age groups, including the incidence, length of hospitalization and hospital costs.
  30. ncbi Does the length of the history influence the outcome of pneumatic reduction of intussusception in children?
    Farhan Tareen
    Children s University Hospital, Temple Street, Dublin 1, Ireland
    Pediatr Surg Int 27:587-9. 2011
    b>Intussusception is the most common cause of acute abdomen in infants and preschool children. Nonoperative reduction using air enema is an established treatment in children with intussusception...
  31. ncbi Intussusception in children in Southern Israel: disparity between 2 populations
    David Greenberg
    The Pediatric Infectious Disease Unit, Soroka University Medical Center, The Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Pediatr Infect Dis J 27:236-40. 2008
    b>Intussusception has been associated with 1 rotavirus vaccine. Our objective was to determine intussusception rates in children in southern Israel during a 15-year period before the introduction of new rotavirus vaccines.
  32. ncbi Intussusception risk after rotavirus vaccination in U.S. infants
    W Katherine Yih
    From the Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute W K Y, T A L, M K, R P, G M L, and the Division of Infectious Diseases and Department of Laboratory Medicine, Boston Children s Hospital G M L all in Boston the Division of Research, Kaiser Permanente Northern California, Oakland T A L the Center for Biologics Evaluation and Research, Food and Drug Administration, Rockville, MD D M, M N Aetna, Blue Bell, PA C N M W Government and Academic Research, HealthCore, Alexandria, VA N S and Comprehensive Health Insights, Humana, Louisville, KY M S
    N Engl J Med 370:503-12. 2014
    International postlicensure studies have identified an increased risk of intussusception after vaccination with the second-generation rotavirus vaccines RotaTeq (RV5, a pentavalent vaccine) and Rotarix (RV1, a monovalent vaccine)...
  33. pmc Trends in intussusception hospitalizations among US infants, 1993-2004: implications for monitoring the safety of the new rotavirus vaccination program
    Jacqueline E Tate
    Division of Viral Diseases, Epidemiology Branch, National Center for Immunizations and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Pediatrics 121:e1125-32. 2008
    ..Because a previous rotavirus vaccine was withdrawn in 1999 after it was associated with intussusception, monitoring for this adverse event with the new vaccine is important...
  34. ncbi Population-based incidence and burden of childhood intussusception in Jeonbuk Province, South Korea
    Dae S Jo
    Department of Pediatrics, Chonbuk National University Hospital, Jeonju, South Korea
    Int J Infect Dis 13:e383-8. 2009
    The aim of this study was to describe the clinical characteristics of childhood intussusception and to estimate the incidence rate of intussusception before the introduction of rotavirus vaccines in Korea.
  35. ncbi Ileocecal Burkitt's lymphoma presenting as ileocolic intussusception with appendiceal invagination and acute appendicitis
    Sheng Mine Wang
    Department of Pediatrics, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    J Formos Med Assoc 109:476-9. 2010
    b>Intussusception is a common cause of abdominal pain in children. Although most cases are idiopathic, about 10% of cases have a pathologic lead point. Burkitt's lymphoma is not a common etiology...
  36. ncbi Intussusception in children seen at Muhimbili National Hospital, Dar es Salaam
    P M R Carneiro
    Department of Surgery, Muhimbili University College of Health Sciences, Dar es Salaam, Tanzania
    East Afr Med J 81:439-42. 2004
    To review infants and children with intussusception and assess its magnitude of concern and any seasonal variation in our environment.
  37. ncbi Childhood intussusception at the Moi teaching and Referral Hospital Eldoret: management challenges in a rural setting
    R T Kuremu
    Department of Surgery, Faculty of Health Sciences, Moi University, Eldoret, Kenya
    East Afr Med J 81:443-6. 2004
    To review the management of childhood intussusception at the Moi Teaching and Referral Hospital, Eldoret and identify factors that require attention for improved outcome.
  38. ncbi Intussusception in early childhood: a cohort study of 1.7 million children
    Thea Kølsen Fischer
    Division of Viral and Rickettsial Diseases, Centers for Disease Control and Prevention, 1600 Clifton Rd, MS A34, Atlanta, GA 30333, USA
    Pediatrics 114:782-5. 2004
    ..To describe incidence and temporal trends of intussusceptions in Danish children during 1980 to 2001...
  39. ncbi Transanal protrusion of intussusception in infants is associated with high morbidity and mortality
    E A Ameh
    Division of Paediatric Surgery, Department of Surgery, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
    Ann Trop Paediatr 28:287-92. 2008
    Although anal protrusion of intussusception in infants is well recognised, it is rarely reported and confusion with rectal prolapse often results in delayed diagnosis and treatment...
  40. ncbi The epidemiology of paediatric intussusception in Singapore: 1997 to 2004
    Irving Charles Boudville
    GlaxoSmithKline Biologicals, Singapore
    Ann Acad Med Singapore 35:674-9. 2006
    ..RRV-TV, was registered in the US in 1998, but withdrawn within a year because of an observed association with intussusception (IS)...
  41. ncbi Intussusception in Kano: a 5-year analysis of pattern, morbidity and mortality
    S T Edino
    Department of Surgery, Bayero University Kano, Nigeria
    Niger J Med 12:221-4. 2003
    b>Intussusception is a common surgical problem in childhood. This study was undertaken to determine the clinico-pathologic pattern of the disease in Kano.
  42. ncbi Adult intussusception in the last 25 years of modern imaging: is surgery still indicated?
    Edwin Onserio Onkendi
    Department of Surgery, Mayo Clinic Rochester, Rochester, MN 55905, USA
    J Gastrointest Surg 15:1699-705. 2011
    ..With current availability of computed tomography, we questioned the role of mandatory operative exploration for all adult intussusceptions...
  43. ncbi Intussusception: trends in clinical presentation and management
    Frances A Justice
    Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Victoria, Australia
    J Gastroenterol Hepatol 21:842-6. 2006
    The association of a rotavirus vaccine and intussusception has renewed interest in understanding the incidence, clinical presentation and outcome of intussusception.
  44. ncbi Incidence of intussusception in early infancy: a capture-recapture estimate for Germany
    S Weis
    Ludwig Maximilians Universitat Munchen, Institute for Social Paediatrics and Adolescent Medicine, Germany
    Klin Padiatr 223:419-23. 2011
    Rotavirus (RV) vaccination with the first generation vaccine (Rotashield) has been associated with intussusception (IS)...
  45. ncbi Effect of rotavirus vaccination programme on trends in admission of infants to hospital for intussusception
    L Simonsen
    National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA
    Lancet 358:1224-9. 2001
    Studies have reported a temporal association between a first dose of rotavirus vaccine (Rotashield) and infant intussusception. We investigated the effect of Rotashield vaccination use on intussusception admissions in ten US states.
  46. ncbi Simultaneous presence of human herpesvirus 6 and adenovirus infections in intestinal intussusception of young children
    Suvi Lappalainen
    Vaccine Research Center, University of Tampere Medical School, Tampere, Finland
    Acta Paediatr 101:663-70. 2012
    This prospective study investigated the role of viral infections in the pathogenesis of intussusception, including human herpesvirus 6 (HHV-6), a known lymphotropic virus.
  47. ncbi Rectal prolapse, rectal intussusception, rectocele, and solitary rectal ulcer syndrome
    R J Felt-Bersma
    Department of Gastroenterology, University Hospital Rotterdam Dijkzigt, The Netherlands
    Gastroenterol Clin North Am 30:199-222. 2001
    ..A laparoscopic rectopexy should be recommended. Intussusception is more an epiphenomenon than a cause of defecatory disorder and should be managed conservatively...
  48. ncbi Prevalence of severe acute rotavirus gastroenteritis and intussusceptions in Ghanaian children under 5 years of age
    Christabel C Enweronu-Laryea
    Department of Child Health, University of Ghana Medical School, Accra, Ghana
    J Infect Dev Ctries 6:148-55. 2012
    ..Pre-vaccine surveillance for burden of rotavirus disease, prevalent rotavirus genotypes, and association between rotavirus disease and intussusceptions helps in monitoring the impact of vaccination...
  49. ncbi Lack of association between rotavirus infection and intussusception: implications for use of attenuated rotavirus vaccines
    Emily J Chang
    UCLA Center for Vaccine Research, Harbor UCLA Medical Center, Torrance, CA 90502, USA
    Pediatr Infect Dis J 21:97-102. 2002
    Withdrawal of the tetravalent rhesus-human rotavirus vaccine Rotashield because of its association with intussusception raised concerns about a potential link between natural rotavirus disease and intussusception...
  50. ncbi Rectal hyposensitivity is uncommon and unlikely to be the central cause of obstructed defecation in patients with high-grade internal rectal prolapse
    N A Wijffels
    Oxford Pelvic Floor Centre, Surgery and Diagnostics, Churchill Hospital, Oxford, UK
    Neurogastroenterol Motil 23:151-4, e30. 2011
    ..This study aimed to evaluate rectal sensory function in patients with obstructed defecation and high-grade internal rectal prolapse...
  51. ncbi Presenting clinical features and outcome in intussusception
    Sule Yalcin
    Department of Pediatric Surgery, Hacettepe University Medical Faculty, Ankara, Turkey
    Indian J Pediatr 76:401-5. 2009
    To evaluate if a correlation exists between the clinical and radiologic characteristics at presentation; and the success of conservative management, morbidity and outcome of patients with intussusception.
  52. ncbi Underestimates of intussusception rates among US infants based on inpatient discharge data: implications for monitoring the safety of rotavirus vaccines
    Margaret M Cortese
    National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    J Infect Dis 200:S264-70. 2009
    Because a previous rotavirus vaccine was associated with intussusception, new rotavirus vaccines are monitored postlicensure for any such association...
  53. ncbi Intussusception-associated hospitalization among Venezuelan infants during 1998 through 2001: anticipating rotavirus vaccines
    Irene Perez-Schael
    Instituto de Biomedicina Fuvesin, Universidad Central de Venezuela, Ministerio de Salud y Desarrollo Social, Carcas, Venezuela
    Pediatr Infect Dis J 22:234-9. 2003
    The first licensed rotavirus vaccine was withdrawn from use in the United States because of a low risk of intussusception. Consequently tests of new rotavirus vaccines will require some baseline knowledge of the rates and treatment of ..
  54. ncbi Workshop on intussusception in African countries--meeting report
    A Duncan Steele
    PATH, Seattle, WA, USA
    Vaccine 30:A185-9. 2012
    ..Because a previous rotavirus vaccine, Rotashield(®), was associated with intussusception, a form of intestinal obstruction among infants, the current rotavirus vaccines were tested in large clinical ..
  55. ncbi Jejunojejunal intussusception secondary to a jejunal lipoma in an adult
    Tsung Hsien Chiang
    J Gastroenterol Hepatol 21:924-6. 2006
  56. pmc Adult intussusception: a retrospective review of 41 cases
    Ning Wang
    General Surgery Department, The First Affiliated Hospital, China Medical University Shenyang 110001, Liaoning Province, China
    World J Gastroenterol 15:3303-8. 2009
    To optimize the preoperative diagnosis and surgical management of adult intussusception (AI).
  57. pmc Intussusception associated with bacterial meningitis
    E Crushell
    Department of Paediatrics, Sligo General Hospital, Ireland
    Arch Dis Child 85:56-7. 2001
    Despite its common association with viral illnesses, intussusception has only rarely been found in the presence of bacterial infections...
  58. ncbi Paediatric intussusception in Calabar, Nigeria
    A E Archibong
    Paediatric Surgery Unit, Department of Surgery, College of Medical Sciences, University of Calabar, Calabar, Nigeria
    East Afr Med J 78:19-21. 2001
    ..To determine prevalence, clinical presentation, evaluate management methods and outcome of paediatric intussusception in Calabar. DESIGN: A retrospective study. SETTING: University of Calabar Teaching Hospital, Calabar, Nigeria...
  59. ncbi [Invagination caused by angiolipoma of the small intestine--a rare cause of occult gastrointestinal hemorrhage]
    M Manner
    Chirurgische Abteilung, Kreiskrankenhaus Calw
    Chirurg 72:305-7. 2001
    ..Ultrasonographic abdominal screening revealed ileo-ileal intussusception with a central hyperechoic tumor suggestive of a lipoma as lead point...
  60. ncbi Clinical implications and surgical management of intussusception in pediatric patients with Burkitt lymphoma
    Himesh Gupta
    Department of Surgery, St Jude Children s Research Hospital, Memphis, TN 38105, USA
    J Pediatr Surg 42:998-1001; discussion 1001. 2007
    b>Intussusception as a presenting feature of Burkitt lymphoma may be associated with early stage disease, which is curable with less intensive therapy...
  61. ncbi Intussusception-associated hospitalisations in southern Germany
    Lyn J Kohl
    Dr von Hauner Children s Hospital, Department of Immunology and Infectiology, Ludwig Maximilians University of Munich, Munich, Germany
    Eur J Pediatr 169:1487-93. 2010
    The primary objective of this epidemiological surveillance study was to estimate the incidence of intussusception (IS) associated with hospitalisation in children <1, <2 and <17 years of age in Germany...
  62. ncbi Association of viral isolates from stool samples with intussusception in children
    Satoshi Okimoto
    Department of Pediatrics, Hiroshima University Graduate School of Biomedical Science, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
    Int J Infect Dis 15:e641-5. 2011
    b>Intussusception is the most common cause of intestinal obstruction in young children. The pathogenesis of intussusception is still not well understood...
  63. pmc Childhood intussusception in Uzbekistan: analysis of retrospective surveillance data
    Renat Latipov
    Reference Laboratory, Tashkent, Uzbekistan
    BMC Pediatr 11:22. 2011
    Estimates of baseline incidence of childhood intussusception could help safety monitoring after the introduction of rotavirus vaccines. We studied the incidence of intussusception in Uzbekistan, a GAVI-fund eligible state in Central Asia.
  64. ncbi Age dependence of the relation between reassortant rotavirus vaccine (RotaShield) and intussusception
    Kenneth J Rothman
    J Infect Dis 193:898; author reply 898-9. 2006
  65. ncbi Retrograde (reverse) jejunal intussusception might not be such a rare problem: a single group's experience of 23 cases
    Steven C Simper
    Rocky Mountain Associated Physicians, Salt Lake City, Utah 84124, USA
    Surg Obes Relat Dis 4:77-83. 2008
    Retrograde (reverse) intussusception of the jejunum is thought to be a very rare occurrence, having been reported approximately 15 times (21 patients) in medical studies...
  66. ncbi A special type of postoperative intussusception: ileoileal intussusception after surgical reduction of ileocolic intussusception in infants and children
    Yu Zuo Bai
    Department of Pediatric Surgery, Shengjing Hospital of China Medical University, Shenyang 110004, PR China
    J Pediatr Surg 44:755-8. 2009
    Postoperative ileoileal intussusception after surgical reduction of ileocolic intussusception in infants and children is extremely rare, and no reports of this special type of postoperative small bowel intussusception have been found in ..
  67. ncbi Trends in intussusception hospitalizations among US infants before and after implementation of the rotavirus vaccination program, 2000-2009
    Catherine Yen
    Epidemic Intelligence Service, Scientific Education and Professional Development Program Office, University of Cape Town, Cape Town
    J Infect Dis 206:41-8. 2012
    Although US data have not documented an intussusception risk with current rotavirus vaccines, international data indicate a possible low risk, primarily after the first dose.
  68. ncbi Postlicensure monitoring of intussusception after RotaTeq vaccination in the United States, February 1, 2006, to September 25, 2007
    Penina Haber
    Centers for Disease Control and Prevention, National Center for Immunizations and Respiratory Diseases, 1600 Clifton Rd, MS A 47, Atlanta, GA 30333, USA
    Pediatrics 121:1206-12. 2008
    ..Marietta, PA) was withdrawn from the US market after postlicensure monitoring identified an association with intussusception. Although the new rotavirus vaccine (RotaTeq; Merck, West Point, PA) introduced in 2006 was not associated ..
  69. ncbi Prospective surveillance study of the management of intussusception in UK and Irish infants
    L Samad
    UCL Institute of Child Health, London, UK
    Br J Surg 99:411-5. 2012
    b>Intussusception is the most common cause of acute intestinal obstruction in infants. This study examined the clinical presentation, management and outcomes of intussusception in this age group.
  70. ncbi Adult intussusception in Asians: clinical presentations, diagnosis, and treatment
    Chun Chao Chang
    Division of Gastroenterology, Department of Internal Medicine, Taipei Medical University Hospital and Digestive Disease Research Center, Taipei Medical University, Taipei, Taiwan
    J Gastroenterol Hepatol 22:1767-71. 2007
    Adult intussusception is a rare clinical entity. The presentations and optimal management of adult intussusception in Asians have seldom been reported...
  71. ncbi Inverted Meckel's diverticulum as a leading point for ileoileal intussusception in an adult: case report
    M Dujardin
    Department of Radiology, AZ VUB, Laarbeeklaan 101, 1090 Jette, Belgium
    Abdom Imaging 27:563-5. 2002
    b>Intussusception due to an inverted Meckel's diverticulum is considered a rare occurrence. We present a case of a 37-year-old male with anemia and melena due to an inverted Meckel's diverticulum at the base of an ileoileal intussusception...
  72. pmc Adult intussusception: case reports and review of literature
    S Yalamarthi
    Department of General Surgery, Falkirk District and Royal Infirmary, Falkirk, Scotland
    Postgrad Med J 81:174-7. 2005
    Adult intussusception occurs infrequently and differs from childhood intussusception in its presentation, aetiology, and treatment...
  73. ncbi Clinical case definition for the diagnosis of acute intussusception
    Julie E Bines
    Department of Gastroenterology and Clinical Nutrition, Royal Children s Hospital, Murdoch Children s Research Institute, University of Melbourne, Parkville, Victoria, Australia
    J Pediatr Gastroenterol Nutr 39:511-8. 2004
    Because of the reported association between intussusception and a rotavirus vaccine, future clinical trials of rotavirus vaccines will need to include intussusception surveillance in the evaluation of vaccine safety...
  74. ncbi Preoperative CT diagnosis of appendiceal intussusception
    Jonah Luzier
    Oregon Health Sciences University, Portland, OR 97239, USA
    AJR Am J Roentgenol 187:W325-6. 2006
  75. ncbi Three-year surveillance of intussusception in children in Switzerland
    Michael Buettcher
    Division of Pediatric Infectious Diseases, University Children s Hospital Basel, PO Box 4005, Basel, Switzerland
    Pediatrics 120:473-80. 2007
    We attempted to obtain baseline data on the incidence of intussusception and its association with gastroenteritis in a cross-sectional observational study in children.
  76. ncbi Intussusception in adults: a 21-year experience in the university-affiliated emergency center and indication for nonoperative reduction
    Hiroaki Omori
    Department of Surgery I, Iwate Medical University, Morioka, Japan
    Dig Surg 20:433-9. 2003
    While intussusception is relatively common in children, it is rare in adults.
  77. ncbi Adult intussusception due to lymphangioma of the colon
    Yoshirou Matsuba
    Department of Surgery, Higashiomiya General Hospital, 5 18 Higashiomiya, Saitama 330 0021, Japan
    J Gastroenterol 38:181-5. 2003
    We present herein a case report of adult intussusception due to lymphangioma of the colon. On May 27, 2000, a 39-year-old woman with right lower abdominal pain was admitted to our hospital...
  78. ncbi Real-time surveillance to assess risk of intussusception and other adverse events after pentavalent, bovine-derived rotavirus vaccine
    Edward A Belongia
    Marshfield Clinic Research Foundation, Epidemiology Research Center ML2, 1000 North Oak Ave, Marshfield, WI 54449, USA
    Pediatr Infect Dis J 29:1-5. 2010
    ..A previously licensed rotavirus vaccine was withdrawn due to elevated risk of intussusception. We prospectively evaluated the risk of intussusception and other pre-specified adverse events among RotaTeq ..
  79. ncbi Intussusception in children: 11-year experience in Vladivostok
    A N Shapkina
    Department of Paediatric Surgery, Vladivostok State Medical University, Vladivostok, Russia
    Pediatr Surg Int 22:901-4. 2006
    Idiopathic intussusception is an important abdominal emergency in infancy and childhood. The nonoperative management by air enema has always been the standard of care in Russia...
  80. ncbi Intussusception among infants given an oral rotavirus vaccine
    T V Murphy
    Epidemiology and Surveillance Division, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    N Engl J Med 344:564-72. 2001
    b>Intussusception is a form of intestinal obstruction in which a segment of the bowel prolapses into a more distal segment...
  81. ncbi Assessment of postlicensure safety of rotavirus vaccines, with emphasis on intussusception
    Julie E Bines
    Department of Paediatrics, University of Melbourne, Melbourne, Australia
    J Infect Dis 200:S282-90. 2009
    ..However, given that intussusception is an extremely rare event, some risk could be detected as the vaccine is administered to a larger number of ..
  82. ncbi Intussusception and rotavirus vaccines: what is the background risk?
    Xavier Saez-Llorens
    Pediatrics, University of Panama, Panama City, Panama
    Pediatr Infect Dis J 23:363-5. 2004
    The first rotavirus vaccine was associated with a small, albeit statistically significant, risk of intussusception in immunized infants...
  83. ncbi Population-based incidence of intussusception and a case-control study to examine the association of intussusception with natural rotavirus infection among indian children
    Rajiv Bahl
    All India Institute of Medical Sciences, New Delhi, India
    J Infect Dis 200:S277-81. 2009
    A rotavirus vaccine previously licensed in the United States was withdrawn because it caused intussusception. Data on background intussusception rates in developing countries are required to plan pre- and postlicensure safety studies for ..
  84. ncbi Intussusception and rotavirus vaccination: a review of the available evidence
    Manish M Patel
    Viral Gastroenteritis Section, MS A47, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Expert Rev Vaccines 8:1555-64. 2009
    ..Owing to the association of the withdrawn Rotashield vaccine with intussusception, these two new rotavirus vaccines underwent large clinical trials of over 60,000 infants each to assess ..
  85. ncbi Nonleukemic granulocytic sarcoma presenting as intussusception of small bowel
    Su Youn Lee
    Department of Surgery, Kyung Hee University College of Medicine, 1 Hoegi dong, Dongdaemun Gu, Seoul 130 702, Korea
    Int J Clin Oncol 13:467-70. 2008
    ..Recently, we discovered one case of nonleukemic GS in the small intestine incidentally when intussusception was suspected...
  86. pmc Intussusception in adults: clinical characteristics, diagnosis and operative strategies
    Savas Yakan
    Department of Surgery, Izmir Education and Research Hospital, Izmir, Turkey
    World J Gastroenterol 15:1985-9. 2009
    To evaluate 20 adults with intussusception and to clarify the cause, clinical features, diagnosis, and management of this uncommon entity.
  87. ncbi Surgical management of adult sigmoid colon intussusception caused by a malignant tumor: report of a case
    Keiji Matsuda
    Deparment of Surgery, Teikyo University School of Medicine, 2 11 1 Kaga, Itabashi ku, Tokyo 173 0003, Japan
    Surg Today 33:768-71. 2003
    ..was divided 5 cm from the peritoneal reflection, and the sigmoid colon was divided 10 cm proximally from the intussusception. The proximal end of the sigmoid colon was brought out as a colostomy...
  88. ncbi The promise of new rotavirus vaccines
    Roger I Glass
    N Engl J Med 354:75-7. 2006
  89. ncbi Factors associated with bowel resection among infants with intussusception in the United States
    Brian Johnson
    Department of Emergency Medicine, Highland General Hospital, Oakland, CA, USA
    Pediatr Emerg Care 28:529-32. 2012
    b>Intussusception is the most common cause of infant bowel obstruction. Because delays in diagnosis can lead to severe outcomes, differentiating milder cases from those with potentially serious outcomes is important.
  90. ncbi Colonic lipoma with florid vascular proliferation and nodule-aggregating appearance related to repeated intussusception
    Shiro Adachi
    Department of Pathology, The City Hospital of Ikeda, Ikeda, Japan
    Pathol Int 55:160-4. 2005
    ..and epithelial regeneration suggested a reparative process, with ischemic damage due to the effects of intussusception being the most likely event...
  91. ncbi Intestinal schistosomiasis manifesting as colonic intussusception arising from a mucocele of the appendix: report of a case
    Mark T C Wong
    Department of General Surgery, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore, Singapore
    Surg Today 38:664-7. 2008
    We report a case of intestinal schistosomiasis manifesting as colonic intussusception resulting from a mucocele of the appendix, caused by the obstruction of appendiceal outflow by schistosome egg-induced fibrosis...
  92. ncbi Bacterial enteritis as a risk factor for childhood intussusception: a retrospective cohort study
    Cade M Nylund
    Air Force Institute of Technology Wright Patterson Air Force Base, Cincinnati, OH, USA
    J Pediatr 156:761-5. 2010
    To assess the relationship between bacterial enteritis and intussusception.
  93. ncbi Symptomatic intestinal lipomas requiring surgical interventions secondary to ileal intussusception and colonic obstruction: report of two cases
    Koray Atila
    Department of General Surgery, Medicine Faculty of Dokuz Eylul University, Izmir, Turkey
    Ulus Travma Acil Cerrahi Derg 13:227-31. 2007
    ..and may occasionally protrude into the lumen, thus causing abdominal pain resulting from obstruction or intussusception or they may become evident through haemorrhage...
  94. ncbi Colocolonic intussusception secondary to an intraluminal lipoma
    Hala Fatima
    Department of Internal Medicine Gastroenterology, Indiana University School of Medicine, Indianapolis, Indiana, USA
    Clin Gastroenterol Hepatol 5:e38. 2007
  95. ncbi Rectal intussusception in symptomatic patients is different from that in asymptomatic volunteers
    L S Dvorkin
    Gastrointestinal Physiology Unit, Centre for Academic Surgery, Royal London Hospital, UK
    Br J Surg 92:866-72. 2005
    Rectal intussusception is a common finding at evacuation proctography in both symptomatic and asymptomatic individuals...
  96. ncbi Emergency helical CT scan in acute abdomen: a case of intestinal intussusception
    John Bramis
    1st Department of Surgery, University of Athens Medical School, Laikon Hospital, Athens, Greece
    Ulus Travma Acil Cerrahi Derg 12:155-8. 2006
    Surgeons are familiar to the nosological entity "partial intestinal obstruction". Intussusception constitutes a rare etiologic factor for this entity but usually remains undiagnosed preoperatively...
  97. pmc Intussusception and colonic ischemia in portal hypertension: a case report
    Timothy P Plackett
    Department of Surgery, Tripler Army Medical Center, Honolulu, HI, USA
    Hawaii Med J 69:39-41. 2010
    Intestinal intussusception is a relatively uncommon occurrence in adults in comparison to pediatric patients...
  98. ncbi Adult intussusception: a 12-year experience, with emphasis on etiology and analysis of risk factors
    W S Huang
    Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung, Taiwan. R.O.C
    Chang Gung Med J 23:284-90. 2000
    BACKGROUND: To determine the incidence, causes, and associated risk factors of adult intussusception. METHODS: Forty-five cases of adult intussusception proven by surgery were collected from 58,000 surgeries performed from December 1986 ..
  99. ncbi Small intestinal intussusception secondary to a submucosal lipoma
    Yulia Gray
    Department of Pathology, Memorial Hospital of Rhode Island, 111 Brewster Street, Pawtucket, RI 02860, USA
    Arch Pathol Lab Med 126:231-2. 2002
  100. ncbi Predictors of failed enema reduction in childhood intussusception
    Frankie B Fike
    The Children s Mercy Hospital, Kansas City, MO 64108, USA
    J Pediatr Surg 47:925-7. 2012
    Initial management of intussusception is enema reduction. Data are scarce on predicting which patients are unlikely to have a successful reduction. Therefore, we reviewed our experience to identify factors predictive of enema failure.
  101. ncbi Can hyperglycaemia cause jejuno-jejunal intussusception?
    T Lahousen
    Diabet Med 20:335-6; author reply 336. 2003

Research Grants14

  1. INDO-US Collaboration to Develop Rotavirus Vaccines
    Pratima Ray; Fiscal Year: 2005
    ..However, it was subsequently withdrawn from the US market because of an increased incidence of intussusception among vaccine recipients...
  2. Enhanced Surveillance for New Vaccine Preventable Diseases
    Mary A Staat; Fiscal Year: 2010
    ..in children hospitalized or cared for as outpatients or in the ED and assessing the background rate of intussusception. In addition, we propose conducting a series of complementary studies in collaborating pediatric practice ..
  3. Development of an Intranasal Rotavirus Subunit Vaccine
    ALEXANDER ANDRIANOV; Fiscal Year: 2002
    ..approved rotavirus vaccine, a live vaccine, was withdrawn from the market in 1999 because of association with intussusception. The safety concerns associated with live vaccines currently in development can be remedied by the ..
  4. Evaluation of rotavirus vaccines in a primate model
    ANTHONY CHOI; Fiscal Year: 2003
    ..The only FDA-approved rotavirus vaccine was withdrawn in 1999 because of its association with intussusception. The subunit rotavirus vaccines that we are developing have been evaluated in a mouse model that measures ..
  5. NON-FLUOROSCOPY TREATMENT OF INTUSSUSCEPTION
    Weimin Shi; Fiscal Year: 1990
    ..the proposed work is to demonstrate and improve a safe air enema technique for non fluoroscopy treatment of intussusception in children and to develop a novel single-chip microprocessor-based instrument for real-time on-site ..
  6. Needle-Free Delivery of Subunit Rotavirus Vaccines
    ANTHONY CHOI; Fiscal Year: 2003
    ..only FDA-approved rotavirus vaccine was withdrawn in 1999 because of its association with bowel obstruction (intussusception)...
  7. Pathogenesis of Intestinal Intussusception and the Role of Rotavirus Infection
    MARGARET CONNER; Fiscal Year: 2007
    unreadable] DESCRIPTION (provided by applicant): Intestinal intussusception is an invagination of one segment of the intestine into an adjacent segment...
  8. "Intravascular Flow Field Regulation of Intussusceptive Angiogenesis"
    Grace Lee; Fiscal Year: 2009
    Two distinct forms of angiogenesis have been documented: sprouting and intussusception. While mechanisms of sprouting angiogenesis have received considerable attention, especially in the context of tumor therapy, relatively little study ..
  9. ENHANCING MUCOSAL IMMUNE RESPONSES BY MICROENCAPSULATION
    Paul Offit; Fiscal Year: 2005
    ..The availability of microencapsulated virus provides a unique opportunity to understand the relationship between APC and protective mucosal immune responses. ..
  10. BIOLOGY OF HUMAN INTRAEPITHELIAL LYMPHOCYTES
    Ellen Ebert; Fiscal Year: 2002
    ..These studies will determine the mechanism of IEL chemotaxis toward secreted products of ECs, why IL-15 is more potent than IL-2 in inducing LAK activity by IELs, and how IL-10 and IL-12 augment this activity. ..
  11. Calorie Restriction Effects on Chromosomal Aberrations
    CHARLEEN MOORE; Fiscal Year: 2003
    ..The results will be essential in identifying potential mechanisms by which CR acts in cancer prevention and delay of the aging process in long-lived species such as the rhesus monkey and humans. ..
  12. Liposomal Opioids Extend Analgesia in Laboratory Animals
    Lisa Krugner Higby; Fiscal Year: 2008
    ..If proven efficacious, these analgesic regimens would lead to a significant change in the post-surgical care of animals used in biomedical research and veterinary medicine. ..
  13. Adnesion Receptors of the Insect Immune System
    JAMES NARDI; Fiscal Year: 2003
    ..Understanding the molecular underpinnings of the insect immune response will clearly help in understanding the fate of pathogens in the blood of insect vectors of human diseases. ..
  14. Rapid Analysis of Influenza Vaccine Effectiveness
    Edward Belongia; Fiscal Year: 2007
    ..Interim and annual estimates of VE with 95% confidence intervals will be provided to CDC, including overall VE and VE for each of the priority age groups. ..