intestinal perforation

Summary

Summary: Opening or penetration through the wall of the INTESTINES.

Top Publications

  1. ncbi The management of complicated diverticulitis and the role of computed tomography
    Andreas M Kaiser
    Department of Colorectal Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Am J Gastroenterol 100:910-7. 2005
  2. doi The impact of spontaneous tumour perforation on outcome following colon cancer surgery
    A S Abdelrazeq
    Department of Colorectal Surgery, St James s University Hospital, Leeds, UK
    Colorectal Dis 10:775-80. 2008
  3. doi Bowel perforation after radiotherapy in a patient receiving sorafenib
    Natascha A J B Peters
    Department of Experimental Oncology, Academic Medical Center, Amsterdam, The Netherlands
    J Clin Oncol 26:2405-6. 2008
  4. ncbi Typhoid intestinal perforation in north central Nigeria
    B T Ugwu
    Department of Surgery Jos University Teaching Hospital, Jos, Nigeria
    West Afr J Med 24:1-6. 2005
  5. doi Retrospective study of technical aspects and complications of endoscopic submucosal dissection for laterally spreading tumors of the colorectum
    T Toyonaga
    Department of Endoscopy, Kobe University Hospital, Kobe, Japan
    Endoscopy 42:714-22. 2010
  6. ncbi Iatrogenic perforation associated with therapeutic colonoscopy: a multicenter study in Japan
    Keisei Taku
    Division of Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan
    J Gastroenterol Hepatol 22:1409-14. 2007
  7. pmc Postoperative outcomes of extremely low birth-weight infants with necrotizing enterocolitis or isolated intestinal perforation: a prospective cohort study by the NICHD Neonatal Research Network
    Martin L Blakely
    University of Tennessee, Health Science Center, Memphis, Tennessee 38105, USA
    Ann Surg 241:984-9; discussion 989-94. 2005
  8. ncbi A clinical, microbiological, and pathological study of intestinal perforation associated with typhoid fever
    Quoc Chanh Nguyen
    Dong Thap Provincial Hospital, Dong Thap, Ho Chi Minh City, Vietnam
    Clin Infect Dis 39:61-7. 2004
  9. ncbi Outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasms in 200 consecutive cases
    Mitsuhiro Fujishiro
    Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Clin Gastroenterol Hepatol 5:678-83; quiz 645. 2007
  10. ncbi Initial repair of iatrogenic colon perforation using laparoscopic methods
    J I Bleier
    Section of Colon and Rectal Surgery, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, NY, USA
    Surg Endosc 22:646-9. 2008

Detail Information

Publications305 found, 100 shown here

  1. ncbi The management of complicated diverticulitis and the role of computed tomography
    Andreas M Kaiser
    Department of Colorectal Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Am J Gastroenterol 100:910-7. 2005
    ..The aim of our study was therefore to define the role of computed tomography (CT) and to analyze its impact on the management of acute diverticulitis...
  2. doi The impact of spontaneous tumour perforation on outcome following colon cancer surgery
    A S Abdelrazeq
    Department of Colorectal Surgery, St James s University Hospital, Leeds, UK
    Colorectal Dis 10:775-80. 2008
    ..The impact of spontaneous tumour perforation on survival following surgery for colon cancer is unclear. This study compares survival outcomes for patients with perforated colonic cancer with stage-matched nonperforated cancer...
  3. doi Bowel perforation after radiotherapy in a patient receiving sorafenib
    Natascha A J B Peters
    Department of Experimental Oncology, Academic Medical Center, Amsterdam, The Netherlands
    J Clin Oncol 26:2405-6. 2008
  4. ncbi Typhoid intestinal perforation in north central Nigeria
    B T Ugwu
    Department of Surgery Jos University Teaching Hospital, Jos, Nigeria
    West Afr J Med 24:1-6. 2005
    Typhoid intestinal perforation is a surgical problem with severe morbidity and high mortality in North Central Nigeria.
  5. doi Retrospective study of technical aspects and complications of endoscopic submucosal dissection for laterally spreading tumors of the colorectum
    T Toyonaga
    Department of Endoscopy, Kobe University Hospital, Kobe, Japan
    Endoscopy 42:714-22. 2010
    ..However, ESD for LST-NG can be technically difficult. The aim of our study was to compare our ESD results for LST-NG and for LST-G...
  6. ncbi Iatrogenic perforation associated with therapeutic colonoscopy: a multicenter study in Japan
    Keisei Taku
    Division of Endoscopy and Gastrointestinal Oncology, National Cancer Center Hospital East, Chiba, Japan
    J Gastroenterol Hepatol 22:1409-14. 2007
    ..Colonic perforation is the serious accidental complication. The aim of this study is to analyze the clinical presentation and management of recent iatrogenic perforations during therapeutic colonoscopy...
  7. pmc Postoperative outcomes of extremely low birth-weight infants with necrotizing enterocolitis or isolated intestinal perforation: a prospective cohort study by the NICHD Neonatal Research Network
    Martin L Blakely
    University of Tennessee, Health Science Center, Memphis, Tennessee 38105, USA
    Ann Surg 241:984-9; discussion 989-94. 2005
    ..infants who underwent initial laparotomy or drainage for necrotizing enterocolitis (NEC) or isolated intestinal perforation (IP); 2) to determine the ability to distinguish NEC from IP preoperatively and the importance of this ..
  8. ncbi A clinical, microbiological, and pathological study of intestinal perforation associated with typhoid fever
    Quoc Chanh Nguyen
    Dong Thap Provincial Hospital, Dong Thap, Ho Chi Minh City, Vietnam
    Clin Infect Dis 39:61-7. 2004
    One of the most serious complications of typhoid fever is intestinal perforation. Of 27 patients admitted to a provincial hospital in the Mekong Delta region of Vietnam who had gastrointestinal perforation secondary to suspected typhoid ..
  9. ncbi Outcomes of endoscopic submucosal dissection for colorectal epithelial neoplasms in 200 consecutive cases
    Mitsuhiro Fujishiro
    Department of Gastroenterology, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Clin Gastroenterol Hepatol 5:678-83; quiz 645. 2007
    ..The clinical outcomes for endoscopic submucosal dissection (ESD), a novel endoluminal surgery for gastrointestinal neoplasm in the colorectum, are reported...
  10. ncbi Initial repair of iatrogenic colon perforation using laparoscopic methods
    J I Bleier
    Section of Colon and Rectal Surgery, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, NY, USA
    Surg Endosc 22:646-9. 2008
    ....
  11. ncbi Phase II study of bevacizumab in patients with platinum-resistant ovarian cancer or peritoneal serous cancer
    Stephen A Cannistra
    Beth Israel Deaconess Medical Center, East Campus KS158, 330 Brookline Ave, Boston, MA 02215, USA
    J Clin Oncol 25:5180-6. 2007
    ....
  12. pmc Hospital and neurodevelopmental outcomes of extremely low-birth-weight infants with necrotizing enterocolitis and spontaneous intestinal perforation
    T A Shah
    Department of Pediatrics, Perinatal Institute, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    J Perinatol 32:552-8. 2012
    We sought to determine the incidence of necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP) in surviving extremely low-birth-weight (ELBW, <1000 g birth weight) infants and to establish the impact of NEC on ..
  13. pmc Immunoregulatory protein profiles of necrotizing enterocolitis versus spontaneous intestinal perforation in preterm infants
    Kathy Yuen Yee Chan
    Department of Paediatrics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong
    PLoS ONE 7:e36977. 2012
    Necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP) are the most common acute surgical emergencies associated with high morbidity and mortality in preterm infants...
  14. ncbi Laparotomy versus peritoneal drainage for necrotizing enterocolitis or isolated intestinal perforation in extremely low birth weight infants: outcomes through 18 months adjusted age
    Martin L Blakely
    University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Pediatrics 117:e680-7. 2006
    Extremely low birth weight (ELBW; < or =1000 g) infants with necrotizing enterocolitis (NEC) or isolated intestinal perforation (IP) are treated surgically with either initial laparotomy or peritoneal drain placement...
  15. doi A large outbreak of typhoid fever associated with a high rate of intestinal perforation in Kasese District, Uganda, 2008-2009
    Karen P Neil
    Epidemic Intelligence Service, Scientific Education and Professional Development Office, Centers for Disease Control and Prevention CDC, Atlanta, Georgia, USA
    Clin Infect Dis 54:1091-9. 2012
    ..We report a large laboratory-confirmed outbreak of typhoid fever in Uganda with a high proportion of intestinal perforations (IPs)...
  16. pmc Spontaneous intestinal perforation in extremely low birth weight infants: association with indometacin therapy and effects on neurodevelopmental outcomes at 18-22 months corrected age
    Rajan Wadhawan
    Division of Neonatology, All Children s Hospital, St Petersburg, Florida, USA
    Arch Dis Child Fetal Neonatal Ed 98:F127-32. 2013
    Spontaneous intestinal perforation (SIP) is associated with the use of postnatal glucocorticoids and indometacin in extremely low birth weight (ELBW) infants...
  17. pmc Outcome of surgical treatment of intestinal perforation in typhoid fever
    Aziz Sumer
    Department of General Surgery, Medical Faculty, University of Yuzuncu Yil, Van 6500, Turkey
    World J Gastroenterol 16:4164-8. 2010
    To represent our clinical experience in the treatment of intestinal perforation arising from typhoid fever.
  18. doi Prenatal or postnatal indomethacin exposure and neonatal gut injury associated with isolated intestinal perforation and necrotizing enterocolitis
    R Sharma
    Division of Neonatology, Department of Pediatrics, University of Florida College of Medicine at Jacksonville, 655 West 8th Street, Jacksonville, FL 32209 6511, USA
    J Perinatol 30:786-93. 2010
    ..To examine the role of indomethacin in neonatal gut injury...
  19. doi Our experience with endoscopic repair of large colonoscopic perforations and review of the literature
    A Trecca
    Department of Endoscopy and Gastroenterology Fabio di Giovambattista, USI Group Rome, Via Baccina 45, 00184 Rome, Italy
    Tech Coloproctol 12:315-21; discussion 322. 2008
    ..Recently successful closure with endoscopic clips has been reported. However large (>10 mm) perforations and perforations occurring during diagnostic colonoscopy are considered a contraindication to endoscopic closure...
  20. doi Small intestinal nonmeckelian diverticulosis
    Konstantinos Makris
    Department of Surgery, Metropolitan Hospital, Athens, Greece
    J Clin Gastroenterol 43:201-7. 2009
    ..The extent of resection may be a problem, especially in patients with extensive disease involving large parts of the bowel. In these cases, clinical judgment is required from the part of surgeon to avoid short bowel syndrome...
  21. ncbi Intestinal perforation as a long-term complication of plug and mesh inguinal hernioplasty: case report
    M Benedetti
    Istituto di Chirurgia Generale e dei Trapianti d Organo Chirurgia Gastroenterologica e Mammaria, IRCCS Policlinico S Matteo Università degli Studi di Pavia, P le Golgi 2, 27100 Pavia, Italy
    Hernia 9:93-5. 2005
    ..We report on a case of sigmoid colon perforation due to a plug of Trabucco hernioplasty performed 2 years previously...
  22. ncbi Endoclipping of iatrogenic colonic perforation to avoid surgery
    Richard Magdeburg
    Chirurgie, Universitatsklinikum Mannheim, Mannheim, BW, Germany
    Surg Endosc 22:1500-4. 2008
    ..Recently, endoscopic clip application was recommended, particularly for iatrogenic perforations, but less is known about the effectiveness of endoluminal repair of colonic perforations with clips...
  23. doi Bowel perforation in non-small cell lung cancer after bevacizumab therapy
    Elisabeth Schellhaas
    Chirurgische Klinik I, Charite Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany
    Invest New Drugs 27:184-7. 2009
    ..Bevacizumab is increasingly used in combination with chemotherapy for treatment of unresectable non-small cell lung cancer. The aim of this report is to underline possible risks associated with this otherwise well-tolerated drug...
  24. pmc The ladies trial: laparoscopic peritoneal lavage or resection for purulent peritonitis and Hartmann's procedure or resection with primary anastomosis for purulent or faecal peritonitis in perforated diverticulitis (NTR2037)
    Hilko A Swank
    Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands
    BMC Surg 10:29. 2010
    ....
  25. ncbi Laparotomy versus peritoneal drainage for necrotizing enterocolitis and perforation
    R Lawrence Moss
    Section of Pediatric Surgery, Yale University School of Medicine, New Haven, Conn 06520 8062, USA
    N Engl J Med 354:2225-34. 2006
    ..We designed this multicenter randomized trial to compare outcomes of primary peritoneal drainage with laparotomy and bowel resection in preterm infants with perforated necrotizing enterocolitis...
  26. ncbi Typhoid ileal perforation: analysis of morbidity and mortality in 89 children
    S O Ekenze
    Department of Pediatric Surgery, University of Nigeria Teaching Hospital, Enugu
    Niger J Clin Pract 11:58-62. 2008
    ..Typhoid ileal perforation is still prevalent in many developing countries. Despite the advances in the management, the outcome in children is still very poor...
  27. pmc Incidence and management of colonoscopic perforations: 8 years' experience
    Hagit Tulchinsky
    Department of Surgery B, Sourasky Medical Center, 6 Veizman St, Tel Aviv 64239, Israel
    World J Gastroenterol 12:4211-3. 2006
    ..To review the experience of a major medical teaching center with diagnostic and therapeutic colonoscopies and to assess the incidence and management of related colonic perforations...
  28. ncbi Accuracy of MDCT in predicting site of gastrointestinal tract perforation
    Bernard Hainaux
    Department of Radiology, Centre Hospitalier Universitaire St Pierre, Universite Libre de Bruxelles, 322 rue Haute, Brussels 1000, Belgium
    AJR Am J Roentgenol 187:1179-83. 2006
    ....
  29. doi Risk of gastrointestinal perforation in patients with cancer treated with bevacizumab: a meta-analysis
    Sanjaykumar Hapani
    Division of Hematology and Medical Oncology, Department of Medicine, Stony Brook University Medical Center, Stony Brook, NY 11794 9447, USA
    Lancet Oncol 10:559-68. 2009
    ..We did a systematic review and meta-analysis of published randomised controlled trials to assess the overall risk of gastrointestinal perforation associated with bevacizumab treatment...
  30. ncbi Colonoscopic perforations: a review of 30,366 patients
    T H Lüning
    Department of Surgery, Canisius Wilhelmina Hospital, Nijmegen, The Netherlands
    Surg Endosc 21:994-7. 2007
    ..This study aimed to determine perforation frequency and the management of endoscopic colonoscopic perforation...
  31. ncbi What is the risk of bowel perforation associated with bevacizumab therapy in ovarian cancer?
    Ernest S Han
    Gynecol Oncol 105:3-6. 2007
  32. doi Risk of perforation from a colonoscopy in adults: a large population-based study
    Gaurav Arora
    Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California 94305 5187, USA
    Gastrointest Endosc 69:654-64. 2009
    ..Previous studies that reported the incidence of perforation from a colonoscopy are limited by small sample sizes, restricted age groups, or single-center data...
  33. pmc Colonoscopic perforation: incidence, risk factors, management and outcome
    Varut Lohsiriwat
    Department of Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Prannok Road, Bangkok 10700, Thailand
    World J Gastroenterol 16:425-30. 2010
    ..The applications of each treatment are discussed. Overall outcomes of patients with CP are also addressed...
  34. ncbi Ascitic fluid carcinoembryonic antigen and alkaline phosphatase levels for the differentiation of primary from secondary bacterial peritonitis with intestinal perforation
    S S Wu
    Division of Gastroenterology, Changhua Christian Medical Center, Taiwan
    J Hepatol 34:215-21. 2001
    ..bacterial peritonitis (SBP) may be difficult to distinguish from secondary peritonitis with occult intestinal perforation; Runyon's criteria (based on ascitic fluid glucose, protein and lactate dehydrogenase levels) are ..
  35. doi Surgical management of necrotizing enterocolitis and isolated intestinal perforation in premature neonates
    Martin L Blakely
    Division of Pediatric Surgery, University of Tennessee Health Science Center, Memphis, TN, USA
    Semin Perinatol 32:122-6. 2008
    Necrotizing enterocolitis (NEC) and isolated intestinal perforation (IP) are two relatively common disease conditions that require neonatal surgical therapy...
  36. ncbi Endoscopic treatment of an iatrogenic perforation of the colon by using endoloop
    Carla Celestino
    The Latin American OMGE OMED Advanced Gastrointestinal Endoscopy Training Center Santiago de Chile, Chile
    Gastrointest Endosc 64:653-4. 2006
  37. ncbi Bowel injury as a complication of laparoscopy
    M van der Voort
    Department of Surgery, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Br J Surg 91:1253-8. 2004
    ..Bowel injury is a rare but serious complication of laparoscopic surgery. This review examines the incidence, location, time of diagnosis, causative instruments, management and mortality of laparoscopy-induced bowel injury...
  38. doi Functional impairments at school age of children with necrotizing enterocolitis or spontaneous intestinal perforation
    Elise Roze
    Division of Neonatology, Beatrix Children s Hospital, University Medical Center Groningen, University of Groningen, Groningen 9713 GZ, The Netherlands
    Pediatr Res 70:619-25. 2011
    ..behavioral outcome at school age of children who had either necrotizing enterocolitis (NEC) or spontaneous intestinal perforation (SIP)...
  39. ncbi Intestinal perforation in very low birth weight infants: growth and neurodevelopment at 1 year of age
    Olubukunola A Adesanya
    Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, NC, USA
    J Perinatol 25:583-9. 2005
    To compare growth and neurodevelopment in surviving very low birth weight (VLBW) infants with an intestinal perforation (IP) caused by necrotizing enterocolitis (NEC) versus spontaneous intestinal perforation (SIP).
  40. ncbi Spontaneous intestinal perforation after oral ibuprofen treatment of patent ductus arteriosus in two very-low-birthweight infants
    M M Tatli
    Division of Neonatology, Department of Paediatrics, Dokuz Eylul University, Izmir, Turkey
    Acta Paediatr 93:999-1001. 2004
    To discuss intestinal side effects of ibuprofen in the treatment of patent ductus arteriosus, after having observed two cases of spontaneous intestinal perforation following ibuprofen treatment.
  41. ncbi Concurrent use of indomethacin and dexamethasone increases the risk of spontaneous intestinal perforation in very low birth weight neonates
    L Paquette
    USC Division of Neonatal Medicine, Department of Pediatrics, Keck School of Medicine, University of Southern California, Los Angeles, CA 90027, USA
    J Perinatol 26:486-92. 2006
    Dexamethasone or indomethacin predisposes very low birth weight (VLBW) neonates to spontaneous intestinal perforation (SIP)...
  42. ncbi Intestinal perforation caused by magnetic toys
    Esperanza Hernández Anselmi
    Department of Paediatric Surgery, Hospital Infantil La Fe, Valencia, Spain
    J Pediatr Surg 42:E13-6. 2007
    ..We report the fifth case in the literature of intestinal perforation and fistula caused by the ingestion of 2 small magnetic pieces of a toy by a 3-year-old boy...
  43. ncbi Thermal injury causing delayed perforation of small bowel after transurethral resection of bladder tumor without evidence of bladder perforation
    Nitya E Abraham
    Department of Urology, New York University School of Medicine, New York, 10016, USA
    Can J Urol 18:5836-8. 2011
    ..This injury highlights the need for particular prudence when resecting and fulgurating bladder tumors using monopolar electrocautery, specifically in the regions adjacent to bowel...
  44. ncbi Laparoscopic repair of colonic perforation associated with colonoscopy: use of passing sutures and endoscopic linear stapler
    A Yamamoto
    Department of Surgery, Koga General Hospital, Miyazaki, Japan
    Surg Laparosc Endosc Percutan Tech 11:19-21. 2001
    ..The current method is beneficial because the perforated lesion is safely and easily closed and postoperative colonic stenosis is avoided...
  45. ncbi Typhoid intestinal perforations: twenty-six year experience
    S Selcuk Atamanalp
    Department of General Surgery, Ataturk University, School of Medicine, 25070 Erzurum, Turkey
    World J Surg 31:1883-8. 2007
    ..One of the most lethal complications of TF is ileal perforation (TIP). Although the mortality of associated with TIP has decreased slightly over the past decade, it is still high...
  46. ncbi Discharge outcomes of extremely low birth weight infants with spontaneous intestinal perforations
    J T Attridge
    Department of Pediatrics, University of Virginia Health System, Charlottesville, VA 22908, and Department of Pediatrics, Carolinas Medical Center, Charlotte, NC, USA
    J Perinatol 26:49-54. 2006
    To examine discharge outcomes of extremely low birth weight infants (ELBW) with spontaneous intestinal perforation (SIP).
  47. ncbi Factors effecting morbidity in typhoid intestinal perforation in children
    Abdurrahman Onen
    Department of Pediatric Surgery, Medical Faculty of Dicle University, Diyarbakir, Turkey
    Pediatr Surg Int 18:696-700. 2002
    To determine the factors affecting morbidity in patients with typhoid intestinal perforation (TIP), 42 patients who had been operated upon for TIP between 1990 and 2000 were reviewed. The average age was 10...
  48. ncbi Maternal factors in extremely low birth weight infants who develop spontaneous intestinal perforation
    Corinne J Ragouilliaux
    Department of Pediatrics, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555 0375, USA
    Pediatrics 120:e1458-64. 2007
    Spontaneous intestinal perforation of the extremely low birth weight infant (< or = 1000 g) is associated with a high incidence of Candida and coagulase-negative Staphylococcus sepsis...
  49. ncbi Life threatening tension pneumoperitoneum from intestinal perforation during air reduction of intussusception
    E Ng
    Departments of Anesthesia and Surgery, Children s Hospital, Boston, MA 02115, USA
    Paediatr Anaesth 12:798-800. 2002
    ..Life threatening tension pneumoperitoneum developed rapidly and immediate needle decompression was life saving in this case. The pathophysiology of hyperacute abdominal compartment syndrome is discussed...
  50. pmc Cytomegalovirus enteritis causing ileal perforation in an elderly immunocompetent individual
    Jae Myung Cha
    Department of Internal Medicine, East West Neo Medical Center, Kyung Hee University College of Medicine, Seoul, Korea
    Yonsei Med J 51:279-83. 2010
    ....
  51. ncbi CMV enteritis causing ileal perforation in underlying lupus enteritis
    Seungmin Bang
    Department of Internal Medicine, Institute for Immunology and Immunological Disease, BK 21 Project for Medical Science, Yonsei University College of Medicine, Shinchon Dong 134, Seodaemoon Gu, 120 752, Seoul, Korea
    Clin Rheumatol 23:69-72. 2004
    ..Her symptoms improved following the initiation of ganciclovir therapy. To the best of our knowledge, this is the first report in the English literature of an ileal perforation due to CMV infection in a patient with lupus enteritis...
  52. ncbi Intestinal perforation due to retained wireless capsule endoscope
    P Gonzalez Carro
    Digestive Unit, Hospital General Mancha Centro, Alcazar de San Juan, Spain
    Endoscopy 37:684. 2005
  53. pmc Ischemic necrosis of small bowel following laparoscopic surgery
    Harrith M Hasson
    University of Chicago, Chicago, Illinois, USA
    JSLS 8:159-63. 2004
    ..Of the 8 cases reported in the surgical literature, 7 were fatal, 1 was not. In this report, we describe the first gynecological case...
  54. ncbi Occult transfixation of the sigmoid colon by suprapubic catheter
    Miles D Witham
    Section of Ageing and Health, Ninewells Hospital, Dundee DD1 9SY, UK
    Age Ageing 31:407-8. 2002
    ..One day after the catheter was changed, he passed faeculent material in the catheter and became unwell with abdominal pain. The catheter tip was visible per rectum...
  55. doi Peritoneal drainage versus laparotomy for necrotizing enterocolitis and intestinal perforation: a meta-analysis
    Juan E Sola
    DeWitt Daughtry Family Department of Surgery, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    J Surg Res 161:95-100. 2010
    To determine whether peritoneal drain (PD) or laparotomy (LAP) is the most effective intervention in premature neonates with necrotizing enterocolitis (NEC) or intestinal perforation (IP).
  56. ncbi Laparoscopic appendectomy for complicated appendicitis: an evaluation of postoperative factors
    C G Ball
    Department of Surgery, Foothills Medical Centre, University of Calgary, 1403 29 Street NW, T2 N 2T9, Calgary, Alberta, Canada
    Surg Endosc 18:969-73. 2004
    ..The use of laparoscopic appendectomy for complicated appendicitis is controversial. Outcomes were compared between patients who had complicated appendicitis and those who had uncomplicated appendicitis...
  57. ncbi Systematic review of the efficacy and safety of colorectal stents
    U P Khot
    Department of Surgery, Darent Valley Hospital, Dartford, UK
    Br J Surg 89:1096-102. 2002
    ..Colorectal stents are being used for palliation and as a 'bridge to surgery' in obstructing colorectal cancers...
  58. ncbi Outcome after emergency surgery for acute perforated diverticulitis in 200 cases
    Jefrey Vermeulen
    Department of Surgery, MCRZ St Clara Hospital and Zuider Hospital, Rotterdam, The Netherlands
    Dig Surg 24:361-6. 2007
    ..The ideal treatment is still controversial. The object of this study was to compare patients with perforated diverticulitis treated either by resection with primary anastomosis (PA) or Hartmann's procedure (HP)...
  59. ncbi New insights into spontaneous intestinal perforation using a national data set: (1) SIP is associated with early indomethacin exposure
    J T Attridge
    University of Virginia Children s Hospital, Charlottesville, VA 22908, USA
    J Perinatol 26:93-9. 2006
    Spontaneous intestinal perforation (SIP) is increasingly common in the premature infant and is associated with significant morbidity...
  60. doi Small intestinal perforation due to metastasis of breast carcinoma: report of a case
    Atsushi Kawasaki
    Department of Surgery, Social Insurance Yokohama Central Hospital, 268 Yamashita cho, Naka ku, Yokohama, 231 8553, Japan
    Surg Today 41:698-700. 2011
    ..It is important to identify metastatic intestinal tumors in patients who have breast cancer...
  61. ncbi Neonatal necrotizing enterocolitis with intestinal perforation in extremely premature infants receiving early indomethacin treatment for patent ductus arteriosus
    Alan M Fujii
    Department of Pediatrics, Boston University School of Medicine, Boston Medical Center, Boston, MA 02218, USA
    J Perinatol 22:535-40. 2002
    ..033). Necrotizing enterocolitis (NEC) with intestinal perforation was the most serious morbidity and occurred in 20% of infants in the ETG, but in no STG infant (p = 0.011)...
  62. doi Multiple intestinal perforation in a patient with Wegener's granulomatosis: a case report and review of the literature
    A C Yildirim
    Turkish Ministry of Health, Ankara Diskapi Education and Researching Hospital, Department of 2nd General Surgery, Diskapi, Ankara, Turkey
    Gastroenterol Clin Biol 34:712-5. 2010
    ..Herein we report a case of a 32-year-old man with extensive intestinal small bowel ischaemic perforation due to Wegener's granulomatosis...
  63. ncbi Ileal perforation caused by cytomegalovirus infection in a patient with recurrent gastric cancer: report of a case
    Susumu Kawate
    Second Department of Surgery, Gunma University School of Medicine, 3 39 22 Showa machi, Maebashi, Gunma 371 8511, Japan
    Surg Today 32:1088-90. 2002
    ..There was no evidence of cancer cell invasion or any other pathogens. Although the prognosis associated with bowel perforation due to CMV infection is poor, emergency surgery saved our patient's life...
  64. ncbi Typhoid intestinal perforation in children: a continuing scourge in a developing country
    Aba F Uba
    Paediatric Surgery Unit, Surgery Department, University of Jos Jos University Teaching Hospital, Murtala Mohammed Way, Jos, Plateau, 930001, Nigeria
    Pediatr Surg Int 23:33-9. 2007
    Typhoid intestinal perforation is a principal cause of morbidity and mortality affecting both adults and children...
  65. ncbi Focal intestinal perforation in extremely-low-birth-weight neonates: etiological consideration from histological findings
    Akio Kubota
    Department of Pediatric Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, 840 Murodo cho, Izumi, Osaka, 594 1101, Japan
    Pediatr Surg Int 23:997-1000. 2007
    In Japan, mortality due to intestinal perforation has been increasing for the last 15 years, as the survival rate of extremely-low-birth-weight neonates (ELBWs) has been increasing...
  66. ncbi [Abdominal compartment syndrome during endoscopic clamping of an intestinal perforation secondary to colonoscopy]
    Magda Lourenço Fernandes
    Hospital das Clinicas, UFMG, BH
    Rev Bras Anestesiol 59:614-7. 2009
    Colonoscopy is widely used for diagnosis, treatment, and control of intestinal disorders. Intestinal perforation, although rare, is the most feared complication. Perforations can be treated by endoscopic clamping...
  67. doi Feasibility of endoscopic closure of an iatrogenic colon perforation occurring during colonoscopy
    Ivan Jovanovic
    Clinic for Gastroenterology and Hepatology, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia
    Gastrointest Endosc 73:550-5. 2011
    ....
  68. doi Preoperative CT staging in sigmoid diverticulitis--does it correlate with intraoperative and histological findings?
    Jorg Peter Ritz
    Department of General, Vascular and Thoracic Surgery, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12200, Berlin, Germany
    Langenbecks Arch Surg 395:1009-15. 2010
    ..This study was designed to evaluate whether the computed tomography (CT) reflects the extent of the inflammation in sigmoid diverticulitis (SD) in order to draw conclusions for selecting the appropriate treatment...
  69. pmc Ileal perforation due to cytomegalovirus infection
    A D Meza
    Department of Medicine, Texas Tech University Health Sciences Center, El Paso 79905
    J Natl Med Assoc 86:145-8. 1994
    ..Typically, a patient with a history of chronic diarrhea, fever, and abdominal pain develops the superimposed picture of an acute abdomen and has pneumoperitonium on radiograph. The prognosis is poor...
  70. ncbi [Self-expandable metallic stent for palliative treatment of colorectal malignant obstructions: risk of perforation]
    R Scurtu
    Service de Chirurgie Generale et Digestive, CHU Tenon, 4, rue de la Chine, 75970 Paris 20, France
    Ann Chir 128:359-63. 2003
    ..The self-expandable metallic stents are a good alternative to surgery for the palliative treatment of malignant colonic obstructions. The aim of this paper was to emphasize the causes which could increase the risk of perforation...
  71. ncbi Direct visualization of perforation sites in patients with a non-traumatic free pneumoperitoneum: added diagnostic value of thin transverse slices and coronal and sagittal reformations for multi-detector CT
    Olivier Ghekiere
    Department of Radiology, Hospital Lapeyronie, Centre Hospitalier Universitaire Montpellier, 371, avenue du Doyen Gaston Giraud, Montpellier, 34295, France
    Eur Radiol 17:2302-9. 2007
    ..The use of 1.25-mm axial slices and reformations intrinsically contained more useful diagnostic information than 5-mm axial slices alone for diagnosis of the perforation site in patients with pneumoperitoneum...
  72. ncbi Pattern of presentation and management of typhoid intestinal perforation in Sagamu, South-West Nigeria: a 15 year study
    A O Tade
    Department of Surgery, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun State, Nigeria
    Niger J Med 17:387-90. 2008
    Mortality from typhoid intestinal perforation remains high in the West African sub-region...
  73. pmc The acute abdomen in the immune compromised host
    Simon P Spencer
    Department of Radiology, St Bartholomew s and The Royal London Hospitals, London, UK
    Cancer Imaging 8:93-101. 2008
    ..The typical radiological appearances of the commonest conditions are illustrated. The challenges and limitations in the radiological diagnosis of these conditions are discussed...
  74. pmc Evolution of imaging for abdominal perforation
    J P Singh
    Department of Radiology, The Whittington Hospital, Royal Free and University College Medical School, London, UK
    Ann R Coll Surg Engl 92:182-8. 2010
    ..However the signs may be subtle or only indirectly related to the site or aetiology of perforation...
  75. ncbi A comparison of the clinical presentation and outcome of focal intestinal perforation and necrotizing enterocolitis in very-low-birth-weight neonates
    Hiroomi Okuyama
    Department of Pediatric Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, 840 Murodo cho, Izumi, Osaka 594 1101, Japan
    Pediatr Surg Int 18:704-6. 2002
    There is controversy about the identity of focal intestinal perforation (FIP) and necrotizing enterocolitis (NEC). To elucidate the difference between them, we reviewed their clinical presentations...
  76. ncbi Intestinal perforation by multiple ectopic pancreatic tissues in a neonate with multiple congenital anomalies
    Kamalesh Pal
    Department of Surgery, Maternity and Children s Hospital, Al Ahsa, Kingdom of Saudi Arabia
    Saudi Med J 29:614-6. 2008
    ..We present a case report of the presence of multiple ectopic pancreatic tissues in the gut causing hemorrhage and perforation in a preterm, extremely low birth weight neonate with multiple congenital anomalies...
  77. ncbi Perforated appendicitis: is laparoscopic operation advisable?
    H Stöltzing
    Department of General, Visceral and Trauma Surgery, Robert Bosch Hospital Stuttgart, Germany
    Dig Surg 17:610-616. 2000
    ..A retrospective study was used to compare laparoscopic appendectomy for perforated appendicitis to open operation...
  78. ncbi T-tube ileostomy for intestinal perforation in extremely low birth weight neonates
    M Rygl
    Department of Pediatric Surgery, 2nd Faculty of Medicine and Teaching Hospital in Motol, Institute of Postgraduate Medicine, Charles University, V Uvalu 84, Prague 5, Czech Republic
    Pediatr Surg Int 23:685-8. 2007
    To evaluate the results of use of T-tube ileostomy in selected cases of intestinal perforation in extremely low birth weight (ELBW) neonates...
  79. ncbi Results of laparoscopic vs. conventional appendectomy in complicated appendicitis
    C Wullstein
    Chirurgische Klinik, Knappschaftskrankenhaus Bochum-Langendreer, , Bochum, Germany
    Dis Colon Rectum 44:1700-5. 2001
    ....
  80. ncbi Repeated intestinal perforation caused by an incomplete form of Behçet's syndrome
    F H Ng
    Department of Medicine, Ruttonjee Hospital, Wan Chai, Hong Kong, China
    J Gastroenterol Hepatol 16:935-9. 2001
    ..We reported herein a rare case of repeated intestinal perforations caused by an incomplete form of Behçet's syndrome in a southern Chinese man...
  81. ncbi Intestinal perforation from primary intra-abdominal fibromatosis
    Erdal Karagulle
    Department of General Surgery, Baskent University, Konya, Turkey
    Saudi Med J 28:639-40. 2007
  82. pmc Gastrointestinal ulceration as a possible side effect of bevacizumab which may herald perforation
    J Tol
    Department of Medical Oncology, Radboud University Nijmegen Medical Centre, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Invest New Drugs 26:393-7. 2008
    ..Given these observations, as well as the relationship between VEGF and mucosal injury healing, we suggest that GI ulcers may occur as a side effect of treatment with bevacizumab and may herald perforation...
  83. ncbi Distinctive distribution of pathogens associated with peritonitis in neonates with focal intestinal perforation compared with necrotizing enterocolitis
    Eric W Coates
    Department of Pediatrics, Wake Forest University School of Medicine, Winston Salem, NC 27157, USA
    Pediatrics 116:e241-6. 2005
    Candida and coagulase-negative staphylococci are emerging pathogens associated with focal intestinal perforation (FIP) and necrotizing enterocolitis (NEC) in neonates...
  84. pmc Perforation of the colon by invading recurrent gastrointestinal stromal tumors during sunitinib treatment
    Hoon Hur
    Department of Surgery, College of Medicine, The Catholic University of Korea, Seoul 150 713, South Korea
    World J Gastroenterol 14:6096-9. 2008
    ..The present case is the first to report that sunitinib, which is administered to treat GIST resistant to imatinib, can cause unexpected colon perforation and subsequent peritonitis...
  85. doi Typhoid intestinal perforation under 5 years of age
    Sebastian O Ekenze
    Department of Paediatric Surgery, University of Nigeria Teaching Hospital, Enugu, Nigeria
    Ann Trop Paediatr 28:53-8. 2008
    Typhoid intestinal perforation is an important cause of morbidity and mortality in many developing countries. The peculiar features in children <5 years old need to be recognised in order to improve outcome.
  86. ncbi CT in acute perforated sigmoid diverticulitis
    Christian Lohrmann
    Division of Diagnostic Radiology, Department of Radiology, University Hospital of Freiburg, Hugstetter Strasse 55, 79106 Freiburg, Germany
    Eur J Radiol 56:78-83. 2005
    ..To assess the value of computed tomography (CT) in patients with acute perforated sigmoid diverticulitis in correlation with the Hinchey classification of perforated diverticular disease...
  87. ncbi Surgical decision making in necrotizing enterocolitis and focal intestinal perforation: predictive value of radiologic findings
    Alda L Tam
    Department of Surgery, Kaiser Permanente Medical Center, Los Angeles, CA 90027, USA
    J Pediatr Surg 37:1688-91. 2002
    ..over the appropriate surgical management (peritoneal drainage versus exploratory laparotomy) of advanced necrotizing enterocolitis and focal intestinal perforation, the authors examined the predictive value of radiologic findings.
  88. ncbi ERCP-related perforations: risk factors and management
    R Enns
    Division of Gastroenterology, Department of Medicine, University of British Columbia, Vancouver, Canada
    Endoscopy 34:293-8. 2002
    ..We reviewed all ERCP-related perforations at our institution to determine: a) their incidence; b) clinical outcomes; c) which management approaches gave the best results; and d) which factors predict a perforation...
  89. doi Bleeding and perforation after outpatient colonoscopy and their risk factors in usual clinical practice
    Linda Rabeneck
    Department of Medicine, University of Toronto, Toronto, Ontario, Canada
    Gastroenterology 135:1899-1906, 1906.e1. 2008
    ..Our objectives were to evaluate the rates of bleeding, perforation, and death associated with outpatient colonoscopy and their risk factors in a population-based study...
  90. ncbi Surgical treatment of perforated diverticular disease: evaluation of factors predicting prognosis in the elderly
    Adolfo Pisanu
    Dipartimento Chirurgico, Materno Infantile e di Scienze dell Immagine, Sezione di Semeiotica Chirurgica, Iniversità Degli Studi di Cagliari, Italy
    Int Surg 89:35-8. 2004
    ..In the elderly, prognosis is strongly related to duration of symptoms, and treatment delay is caused by late hospitalization because of a low sensibility to the disease symptoms in old people...
  91. ncbi Spontaneous localized intestinal perforation in very-low-birth-weight infants: a distinct clinical entity different from necrotizing enterocolitis
    Wolfgang Pumberger
    Division of Pediatric Surgery, Department of Surgery, University of Vienna, Vienna, Austria
    J Am Coll Surg 195:796-803. 2002
    Idiopathic spontaneous intestinal perforation (SIP), a distinct clinical entity different from necrotizing enterocolitis (NEC), has an increasing prevalence in very-low-birth-weight infants...
  92. pmc Treatment of perforated diverticulitis with generalized peritonitis: past, present, and future
    Jefrey Vermeulen
    Department of Colorectal Surgery, Erasmus Medical Center, Dr Molewaterplein 40, 3015 GD, Rotterdam, The Netherlands
    World J Surg 34:587-93. 2010
    ..The supposed optimal treatment of perforated diverticulitis with generalized peritonitis has changed several times during the last century, but at present is still unclear...
  93. ncbi Radiofrequency thermal ablation of abdominal tumors: lessons learned from complications
    Hyunchul Rhim
    Department of Diagnostic Radiology, Hanyang University Hospital, 17 Haengdang dong, Sungdong Ku, 133 792 Seoul, Korea
    Radiographics 24:41-52. 2004
    ..The standard of care for decreasing the morbidity of complications consists of prevention (including careful patient selection), early detection, and prompt, appropriate treatment...
  94. ncbi Endoscopic repair of a colonic perforation following polypectomy using an endoclip
    Sonny S Dhalla
    Brandon Regional Health Centre, Brandon, Manitoba
    Can J Gastroenterol 18:105-6. 2004
    ..Endoscopic repair using an endoclip device for colonic perforation following polypectomy is described. This is the first case report of a repair following a regular polypectomy-induced perforation described in the English literature...
  95. ncbi Typhoid perforation still a common problem: situation in Pakistan in comparison to other countries of low human development
    Hafiz Naweed Ahmed
    Islamic International Medical College Railway Hospital, Multan
    J Pak Med Assoc 56:230-2. 2006
    ..The results of the study were similar to those of Indian studies but better than African studies. The situation warrants attention of health care providers and policy makers...
  96. doi Onset and clinical course of bleeding and perforation after outpatient colonoscopy: a population-based study
    Linda Rabeneck
    Department of Medicine, Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada
    Gastrointest Endosc 73:520-3. 2011
    ..However, evidence from population-based studies is lacking on the time period over which monitoring is needed to detect these adverse events...
  97. ncbi Risk factors for enteric perforation in patients with typhoid Fever
    Salih Hosoglu
    Department of Clinical Microbiology and Infectious Diseases, Dicle University Hospital, Diyarbakir, Turkey
    Am J Epidemiol 160:46-50. 2004
    ..10, 1.35; p = 0.001) were significant predictors of perforation. A short duration of symptoms, inadequate antimicrobial therapy, male sex, and leukopenia are independent risk factors for enteric perforation in patients with typhoid fever...
  98. ncbi Small intestinal perforation and necrotizing fasciitis after abdominal liposuction
    Devesh Sharma
    Department of General Surgery, Geisinger Medical Center, 100 North Academy Avenue, Danville, PA, 17822, USA
    Aesthetic Plast Surg 30:712-6. 2006
    ..Subsequent peritoneal cavity exploration showed two perforations in the mid ileum with gross peritoneal cavity contamination...
  99. ncbi Management of bevacizumab-associated bowel perforation: a case series and review of the literature
    B D Badgwell
    Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
    Ann Oncol 19:577-82. 2008
    ..This study examined the various approaches to the management of perforation and the associated outcomes in patients with bevacizumab-associated bowel perforation at a tertiary cancer center...
  100. pmc In-utero cocaine exposure and neonatal intestinal perforation: a case report
    M Young
    Department of Pediatrics, District of Columbia General Hospital, Washington 20003, USA
    J Natl Med Assoc 87:889-91. 1995
    This article describes a case of spontaneous neonatal intestinal perforation in a preterm infant with evidence of intrauterine exposure to cocaine...
  101. ncbi Perforation during colonoscopy in endoscopic ambulatory surgical centers
    Louis Y Korman
    Metropolitan Gastroenterology Group, 2021 K St NW T 110, Washington DC 20006, USA
    Gastrointest Endosc 58:554-7. 2003
    ..01% to 0.3% of procedures, but the frequency in ambulatory settings is unknown. This study determined the number of perforations occurring within a network of endoscopic ambulatory surgery centers...

Research Grants13

  1. GI-Safer Formulation of Indomethacin for use in Preterm Neonates
    UPENDRA K MARATHI; Fiscal Year: 2010
    ..GI tract, which can be manifest in the related diseases Necrotizing Enterocolitis (NEC) and Spontaneous Intestinal Perforation (SIP)...
  2. GI-Safer Formulation of Indomethacin for use in Preterm Neonates
    UPENDRA K MARATHI; Fiscal Year: 2013
    ..GI tract, which can be manifest in the related diseases Necrotizing Enterocolitis (NEC) and Spontaneous Intestinal Perforation (SIP)...
  3. TAM receptor tyrosine kinases in inflammatory bowel disease
    Carla Rothlin; Fiscal Year: 2013
    ..It can progress to serious complications due to severe inflammation, like intestinal perforation, fistula formation and/or toxic megacolon...
  4. Early Events in Diclofenac Enteropathy
    MARY MOSLEN; Fiscal Year: 2004
    ..e., inflammation, lesions and blood loss) plus high risks of hospitalization and death secondary to intestinal perforation. Specific Aim I will characterize the hypothesized critical early sites of adduct formation utilizing ..
  5. Prophylaxis of adrenal insufficiency to prevent CLD
    Kristi Watterberg; Fiscal Year: 2005
    ..If this study confirms the benefits seen in the pilot study, it will result in a significant improvement in health care for premature infants, both by introducing a beneficial new therapy, and by avoiding higher dose dexamethasone. ..
  6. Paracrine Regulation of IGF-I in the Developing Ileum
    Phillip Gordon; Fiscal Year: 2006
    ..abstract_text> ..
  7. Phase II Study of 44Gy from 131I-81C6 for CNS Tumors
    David Reardon; Fiscal Year: 2004
    ..To further define the toxicity of this approach and Specific Aim 3.To determine the impact of this therapy on quality of life. ..
  8. Excellence in Clinical Research in Children's Surgery
    R Moss; Fiscal Year: 2008
    ..abstract_text> ..
  9. RNA editing and its inhibition of HIV-1 replication in human macrophage
    Yoshihiko Hoshino; Fiscal Year: 2007
    ..These studies will establish if ADAR1 impacts on viral replication and mutation and will be the basis of further investigation on the impact of drug abuse on the expression of ADAR1. [unreadable] [unreadable] [unreadable]..
  10. Statistical Methods for Clinical Trials with Twin Births
    Michele Shaffer; Fiscal Year: 2007
    ..Thus, the effects of trial design and analysis need to be quantified and taken into consideration for studies that involve singletons and twin births. [unreadable] [unreadable] [unreadable] [unreadable]..
  11. SURGERY FOR NEC IN HUMAN INFANTS-- A RANDOMIZED TRIAL
    R Moss; Fiscal Year: 2002
    ..We believe that we have the necessary personnel and resources in place to complete the first randomized controlled trial for neonatal surgery in the United States. ..
  12. Insulin Resistance and Adenomas of the Colorectum
    Theodore Levin; Fiscal Year: 2003
    ..abstract_text> ..