Genomes and Genes
esophageal and gastric varices
Summary: Dilated blood vessels in the ESOPHAGUS or GASTRIC FUNDUS that shunt blood from the portal circulation (PORTAL SYSTEM) to the systemic venous circulation. Often they are observed in individuals with portal hypertension (HYPERTENSION, PORTAL).
Publications272 found, 100 shown here
- Prediction of esophageal varices in patients with cirrhosisRavi Madhotra
Liver Service, Division of Gastroenterology and Hepatology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
J Clin Gastroenterol 34:81-5. 2002..To identify predictors of esophageal varices (EV) using available clinical, laboratory, and diagnostic imaging variables...
- Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosisGuadalupe Garcia-Tsao
Section of Digestive Diseases, Yale University School of Medicine and VACT Healthcare System, New Haven, CT, USA
Hepatology 46:922-38. 2007
- Early use of TIPS in patients with cirrhosis and variceal bleedingJuan Carlos Garcia-Pagan
Hepatic Hemodynamic Laboratory, Liver Unit, Institut de Malalties Digestives i Metaboliques, University of Barcelona, Barcelona, Spain
N Engl J Med 362:2370-9. 2010..This study evaluated the earlier use of TIPS in such patients...
- Balloon-occluded retrograde transvenous obliteration of gastric varices with gastrorenal shunt: long-term follow-up in 78 patientsTeruhisa Ninoi
Department of Radiology, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
AJR Am J Roentgenol 184:1340-6. 2005..Our aim was to evaluate the long-term clinical results after balloon-occluded retrograde transvenous obliteration (B-RTO) for gastric varices with spontaneous gastrorenal shunt...
- Balloon-occluded retrograde transvenous obliteration of gastric varices: outcomes and complications in 49 patientsSung Ki Cho
Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Ilwon dong 50, Kangnam Ku, Seoul 135 710, Korea
AJR Am J Roentgenol 189:W365-72. 2007..Our aim was to evaluate the clinical outcomes, techniques, and complications of balloon-occluded retrograde transvenous obliteration for treating gastric varices with spontaneous gastrosystemic shunts...
- Incidence and natural history of small esophageal varices in cirrhotic patientsManuela Merli
II Gastroenterology Unit, Department of Clinical Medicine, University of Rome La Sapienza, Viale dell Universita 37, 00185 Rome, Italy
J Hepatol 38:266-72. 2003..The incidence and natural history of small esophageal varices (EV) in cirrhotics may influence the frequency of endoscopies and the decision to start a pharmacological treatment in these patients...
- Improved survival after variceal bleeding in patients with cirrhosis over the past two decadesNicolas Carbonell
Hopital Saint Antoine, Service d Hepatogastroenterologie, AP HP, Universite Pierre et Marie Curie, Paris, France
Hepatology 40:652-9. 2004....
- Measurement of spleen stiffness by acoustic radiation force impulse imaging identifies cirrhotic patients with esophageal varicesYoshitaka Takuma
Department of Gastroenterology, Kurashiki Central Hospital, Okayama, Japan
Gastroenterology 144:92-101.e2. 2013..We evaluated whether spleen stiffness (SS), measured by acoustic radiation force impulse imaging, can identify patients who have esophageal varices (EVs); those without EVs would not require endoscopic examination...
- A pathophysiologic, gastroenterologic, and radiologic approach to the management of gastric varicesBarbara M Ryan
Department of Gastroenterology, Manchester Royal Infirmary, UK
Gastroenterology 126:1175-89. 2004..The role of some newer interventional radiologic techniques requires further appraisal. This review describes the pathophysiology, diagnosis, natural history, endoscopic, and interventional radiologic treatment options for GV...
- Pathomorphology of esophageal and gastric varicesMasahiro Arakawa
Department of Pathology, Omuta City General Hospital, Omuta, Japan
Semin Liver Dis 22:73-82. 2002..Most ruptures occur in this critical area. The basic differences between esophageal and gastric varices are the layers in which the varicose veins form: the lamina propria mucosae and submucosa in the ..
- Hepatic venous pressure gradient predicts clinical decompensation in patients with compensated cirrhosisCristina Ripoll
Veterans Affairs CT Healthcare System, Yale University School of Medicine, West Haven, Connecticut 06516, USA
Gastroenterology 133:481-8. 2007....
- Long-term result of endoscopic Histoacryl (N-butyl-2-cyanoacrylate) injection for treatment of gastric varicesEun Jung Kang
Institute for Digestive Research, Department of Internal Medicine, Soonchunhyang University College of Medicine, Seoul Hospital, Seoul 140 743, South Korea
World J Gastroenterol 17:1494-500. 2011..To evaluate the long-term efficacy and safety of endoscopic obliteration with Histoacryl(®) for treatment of gastric variceal bleeding and prophylaxis...
- Measurement of spleen stiffness to evaluate portal hypertension and the presence of esophageal varices in patients with HCV-related cirrhosisAntonio Colecchia
Department of Clinical Medicine, University of Bologna, Bologna, Italy
Gastroenterology 143:646-54. 2012..We compared the diagnostic performance of spleen stiffness (SS) measurement by transient elastography with that of liver stiffness (LS) and of other recently proposed noninvasive tests...
- Noninvasive assessment of portal hypertension in patients with cirrhosisDominique Thabut
Institut National de la Santé et de la Recherche Médicale Unité 773, Centre de recherche Biomedicale Bichat Beaujon, Paris, France
Hepatology 53:683-94. 2011..Although most of these noninvasive methods effectively identify severe portal hypertension, methods for diagnosing moderate portal hypertension need to be developed; this shows that further investigation is needed in this field...
- General rules for recording endoscopic findings of esophagogastric varices (2nd edition)Takashi Tajiri
The Japan Society for Portal Hypertension, Tokyo, Japan
Dig Endosc 22:1-9. 2010..The revised rules are simpler and more straightforward than the former rules and include newly recognized findings of portal hypertensive gastropathy and a new classification for endoscopic ultrasonographic findings...
- Etiology of portal hypertension may influence gastrointestinal transitR Sadik
Division of Gastroenterology, Institute of Internal Medicine, Sahlgrenska University Hospital, University of Goteborg, Goteborg, Sweden
Scand J Gastroenterol 38:1039-44. 2003..We have studied gastric emptying. small-bowel transit and colonic transit in patients with portal hypertension. The association between small-bowel bacterial overgrowth and gastrointestinal transit was assessed...
- Endothelial dysfunction in the regulation of cirrhosis and portal hypertensionYasuko Iwakiri
Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
Liver Int 32:199-213. 2012..The article ends by discussing the future directions of the study for endothelial dysfunction...
- A randomized trial of endoscopic treatment of acute gastric variceal hemorrhage: N-butyl-2-cyanoacrylate injection versus band ligationPen Chung Tan
Division of Gastroenterology, Department of Medicine, Veterans General Hospital Taipei and National Yang Ming University School of Medicine, Taipei, Taiwan
Hepatology 43:690-7. 2006..Severe complications attributable to these two treatments were rare. In conclusion, the efficacy of GVL to control active GVH appears not different to GVO, but GVO is associated with a lower GV rebleeding rate...
- Natural history of portal hypertension in patients with cirrhosisR de Franchis
Department of Internal Medicine, University of Milan, Italy
Clin Liver Dis 5:645-63. 2001..Acute bleeding from portal hypertensive gastropathy seems to be relatively uncommon, and less severe than bleeding from varices...
- Liver stiffness measurement predicts severe portal hypertension in patients with HCV-related cirrhosisFrancesco Vizzutti
Dipartimento di Medicina Interna, Center for Research, Higher Education and Transfer DENOThe, Firenze, Italy
Hepatology 45:1290-7. 2007....
- Patency of stents covered with polytetrafluoroethylene in patients treated by transjugular intrahepatic portosystemic shunts: long-term results of a randomized multicentre studyChristophe Bureau
Federation Digestive Purpan, Service Hepato Gastro Enterologie CHU Toulouse, Toulouse, France
Liver Int 27:742-7. 2007..In conclusion, the improvement in TIPS patency by using covered prostheses is maintained over time with a decreased risk of encephalopathy, while the risk of death was not increased...
- Banding ligation versus beta-blockers as primary prophylaxis in esophageal varices: systematic review of randomized trialsLise L Gluud
Cochrane Hepato Biliary Group, Copenhagen Trial Unit, Center for Clinical Intervention Research, Rigshospitalet, Copenhagen, Denmark
Am J Gastroenterol 102:2842-8; quiz 2841, 2849. 2007..To compare banding ligation versus beta-blockers as primary prophylaxis in patients with esophageal varices and no previous bleeding...
- Endoscopic ligation compared with sclerotherapy for bleeding esophageal varices in children with extrahepatic portal venous obstructionShowkat Ali Zargar
Department of Gastroenterology, Sher I Kashmir Institute of Medical Sciences, Srinagar, Kashmir, India
Hepatology 36:666-72. 2002..4% vs. 10%, P =.67). In conclusion, variceal band ligation in children is a safe and effective technique that achieves variceal eradication more quickly, with a lower rebleeding rate and fewer complications compared with sclerotherapy...
- Long-term results of balloon-occluded retrograde transvenous obliteration for the treatment of gastric varices and hepatic encephalopathyT Fukuda
Department of Radiology, Kobe University School of Medicine, Japan
J Vasc Interv Radiol 12:327-36. 2001..To evaluate the long-term results of balloon-occluded retrograde transvenous obliteration (B-RTO) for the treatment of gastric varices (GV) and hepatic encephalopathy...
- Non-invasive predictors of the presence of large oesophageal varices in patients with cirrhosisK C Thomopoulos
Department of Internal Medicine, Division of Gastroenterology University Hospital of Patras, Patras, Greece
Dig Liver Dis 35:473-8. 2003..The aim of the present study was to determine whether clinical or laboratory non-endoscopic parameters could predict the presence of large oesophageal varices...
- Antibiotic prophylaxis after endoscopic therapy prevents rebleeding in acute variceal hemorrhage: a randomized trialMing Chih Hou
Division of Gastroenterology, Department of Medicine, Taipei Veterans General Hospital, No 201 Sec 2 Shih Pai Road, Taipei, Taiwan 11217, ROC
Hepatology 39:746-53. 2004..In conclusion, antibiotic prophylaxis can prevent infection and rebleeding as well as decrease the amount of blood transfused for patients with acute GEVB following endoscopic treatment...
- [Non-invasive diagnosis of portal hypertension in cirrhosis. Application to the primary prevention of varices]Nina Dib
Laboratoire HIFIH, UPRES EA 3859, IFR 132, Université et Service d Hépato Gastroentérologie, CHU, Angers
Gastroenterol Clin Biol 29:975-87. 2005....
- Prevention of variceal rebleedingJaume Bosch
Hepatic Haemodynamic Laboratory, Liver Unit, Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, University of Barcelona, 08036, Barcelona, Spain
Lancet 361:952-4. 2003..Endoscopic techniques include band ligation (EBL) and injection sclerotherapy (EIS). Drug approaches are based on non-selective beta blocker with or without isosorbide-5-mononitrate (ISMN)...
- Endoscopic Doppler US-guided injection therapy for gastric varices: case reportGiorgio Battaglia
Department of Medical and Surgical Sciences, IV Surgery Clinic, University of Padova, Italy
Gastrointest Endosc 57:608-11. 2003
- [Measurement of hepatic venous pressure gradient in liver cirrhosis: relationship with the status of cirrhosis, varices, and ascites in Korea]Moon Young Kim
Department of Internal Medicine and Institute of Lifelong Health, Yonsei University Wonju College of Medicine, Wonju, Korea
Korean J Hepatol 14:150-8. 2008..The aim of this study was to determine the relationships between HVPG and the complications or status of cirrhosis...
- Liver stiffness measurement selects patients with cirrhosis at risk of bearing large oesophageal varicesFarhad Kazemi
Hepatology Department, Hopital Jean Verdier, APHP, Universite Paris 13, Bondy, France
J Hepatol 45:230-5. 2006..Periodic endoscopic screening for oesophageal varices is recommended in patients with cirrhosis, but might be limited to a subgroup of patients if a simple non-invasive test was available to select those at risk of bleeding...
- Long-term outcomes of acute gastric variceal bleeding in 48 patients following treatment with cyanoacrylatePetruska Marques
Department of Gastroenterology, Gastrointestinal Endoscopy Division, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
Dig Dis Sci 53:544-50. 2008..1) Study the effectiveness of intravariceal injection of n-butyl-2-cyanoacrylate to treat acute gastric variceal (GV) bleeding and (2) study the impact of the type of GV and hepatic function on endoscopic hemostasis and mortality outcomes...
- TIPS versus transcatheter sclerotherapy for gastric varicesTeruhisa Ninoi
Department of Radiology, Osaka City University Graduate School of Medicine, 1 4 3 Asahi machi, Abeno Ku, Osaka 545 8585, Japan
AJR Am J Roentgenol 183:369-76. 2004..The purpose of our study was to compare the efficacy and long-term results of transjugular intrahepatic portosystemic shunt (TIPS) with those of transcatheter sclerotherapy for the treatment of gastric varices...
- Cost-effectiveness of N-butyl-2-cyanoacrylate (histoacryl) glue injections versus transjugular intrahepatic portosystemic shunt in the management of acute gastric variceal bleedingS Mahadeva
Department of Hepatology and Liver Transplantation, St James s University Hospital, Beckett Street, Leeds LS9, United Kingdom
Am J Gastroenterol 98:2688-93. 2003..Cost-effectiveness analyses of these methods are lacking...
- Cirrhosis and bleeding: the need for very early managementDelphine Nidegger
Institut de Santé Publique Faculté de Médecine de Poitiers, Poitiers, France
J Hepatol 39:509-14. 2003..In a prospective cohort study in which the choice of prophylactic therapy was left to each practitioner, we followed cirrhotic patients with medium/large varices to determine factors predictive of bleeding and death...
- [Effect of endoscopic sclerotherapy using N-butyl-2-cyanoacrylate in patients with gastric variceal bleeding]Jae Woo Kim
Department of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea
Korean J Hepatol 12:394-403. 2006..This study was conducted to evaluate the efficacy of n-butyl-2-cyanoacrylate injection therapy for patients suffering with gastric variceal bleeding...
- A cost-utility analysis of secondary prophylaxis for variceal hemorrhageJoel H Rubenstein
Division of Gastroenterology, University of Michigan Health System, Ann Arbor, Michigan 48109 0362, USA
Am J Gastroenterol 99:1274-88. 2004..Secondary prophylaxis for esophageal variceal hemorrhage (VH) is recommended, but there has never been a cost-utility analysis of its implementation...
- The effects of cefazolin on cirrhotic patients with acute variceal hemorrhage after endoscopic interventionsHuang Wei Xu
Division of Hepato Gastroenterology, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, 123, Ta Pei Road, Niao Sung, Kaohsiung 833, Taiwan
Surg Endosc 25:2911-8. 2011..This study aimed to explore the effects of cefazolin on the outcome of cirrhotic patients with acute variceal hemorrhage after endoscopic interventions...
- Acute management of refractory variceal bleeding in liver cirrhosis by self-expanding metal stentsA Dechene
Department of Gastroenterology and Hepatology, University Hospital Essen, Essen, Germany
Digestion 85:185-91. 2012..With this study, we aimed to evaluate the implantation of self-expanding metal stents (SEMS) for the management of therapy-refractory variceal bleeding...
- The role of the transjugular intrahepatic portosystemic stent shunt (TIPSS) in the management of bleeding gastric varices: clinical and haemodynamic correlationsD Tripathi
Centre for Liver and Digestive Disorders and Department of Medicine, Royal Infirmary of Edinburgh, UK
Gut 51:270-4. 2002..Although it has been reported that gastric varices can bleed at pressures of < or = 12 mm Hg, this phenomenon has been little studied in the clinical setting...
- Effectiveness of combined pharmacologic and ligation therapy in high-risk patients with acute esophageal variceal bleedingSalvador Augustin
Liver Unit Department of Internal Medicine, Universitat Autonoma de Barcelona, Spain
Am J Gastroenterol 106:1787-95. 2011..The effectiveness of currently recommended standard therapy (drugs plus endoscopic ligation) for different risk subgroups and the validity of available risk criteria in clinical practice are unknown...
- A randomized controlled trial of cyanoacrylate versus alcohol injection in patients with isolated fundic varicesShiv K Sarin
Department of Gastroenterology, G B Pant Hospital, New Delhi, India
Am J Gastroenterol 97:1010-5. 2002..A prospective study was undertaken to compare the efficacy and safety of GV sclerotherapy using alcohol and GV obturation using cyanoacrylate glue...
- Balloon-occluded retrograde transvenous obliteration of gastric fundal varices with hemorrhageMikiya Kitamoto
First Department of Internal Medicine, Hiroshima University School of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
AJR Am J Roentgenol 178:1167-74. 2002..This study was performed to evaluate the clinical efficacy, feasibility, and complications of balloon-occluded retrograde transvenous obliteration for patients with hemorrhage from gastric fundal varices...
- Bucrylate treatment of bleeding gastric varices: 12 years' experienceR Kind
First Surgical Department, Universita di Verona, Italy
Endoscopy 32:512-9. 2000..In this study we report on our experience with the use of Bucrylate (Hystoacryl) for the treatment of gastric varices over a period of more than a decade...
- Gastric varices: an updated review of managementShayan Irani
Digestive Disease Institute, Virginia Mason Medical Center, Seattle, WA 98111, USA
J Clin Gastroenterol 45:133-48. 2011..We suggest an algorithm for the management based on the etiology of the gastric varices, severity of the underlying liver disease, and local availability and expertise...
- A prospective, randomized trial of butyl cyanoacrylate injection versus band ligation in the management of bleeding gastric varicesG H Lo
Division of Gastroenterology, Department of Medicine, Kaohsiung Veterans General Hospital, National Yang Ming University, Taipei, Taiwan, Republic of China
Hepatology 33:1060-4. 2001..01). Nine patients of group A and 14 patients of group B died (P = .05). In conclusion, endoscopic obturation using cyanoacrylate proved more effective and safer than band ligation in the management of bleeding gastric varices...
- Propranolol for the prevention of first esophageal variceal hemorrhage: a lifetime commitment?D R Abraczinskas
Gastrointestinal Unit, Massachusetts General Hospital, Boston, MA, USA
Hepatology 34:1096-102. 2001..Patients who discontinue beta blockers experience increased mortality compared with an untreated population. These observations support the current practice of indefinite prophylactic therapy...
- Spleen assessment by Acoustic Radiation Force Impulse Elastography (ARFI) for prediction of liver cirrhosis and portal hypertensionSimona Bota
Department of Gastroenterology and Hepatology University of Medicine and Pharmacy, Timisoara, Romania
Med Ultrason 12:213-7. 2010....
- Complications and outcomes in chronic liver diseaseRobert S Rahimi
Division of Digestive and Liver Disease, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8887, USA
Curr Opin Gastroenterol 27:204-9. 2011..Studies of the complications, management and outcomes in patients with CLD over the last 18 months are reviewed...
- A randomized controlled trial comparing ligation and sclerotherapy as emergency endoscopic treatment added to somatostatin in acute variceal bleedingCandid Villanueva
Gastrointestinal Bleeding Unit, Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
J Hepatol 45:560-7. 2006..However, which emergency endoscopic treatment combines better with drugs has not been clarified. This study compares the efficacy and safety of variceal ligation and sclerotherapy as emergency endoscopic treatment added to somatostatin...
- Variceal ligation plus nadolol compared with ligation for prophylaxis of variceal rebleeding: a multicenter trialJoaquín de la Peña
Hospital Universitario Marques de Valdecilla, Santander, Spain
Hepatology 41:572-8. 2005..In conclusion, nadolol plus EVL reduces the incidence of variceal rebleeding compared with EVL alone. A combined treatment could lower the probability of variceal recurrence after eradication...
- Low incidence of complications from endoscopic gastric variceal obturation with butyl cyanoacrylateLiu Fang Cheng
Department of Gastroenterology and Hepatology, Chinese People s Liberation Army General Hospital, Beijing, China
Clin Gastroenterol Hepatol 8:760-6. 2010..Endoscopic variceal obturation with tissue adhesive is used to control gastric variceal bleeding. We investigated the prevalence of serious complications from this therapy...
- Clinical course of alcoholic liver cirrhosis: a Danish population-based cohort studyPeter Jepsen
Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus, Denmark
Hepatology 51:1675-82. 2010..Subsequent complications occurred in an unpredictable order among patients with ascites or variceal bleeding...
- Detection of submucosal gastric fundal varices with multi-detector row CT angiographyJ K Willmann
Institute of Diagnostic Radiology, University Hospital Zurich, Switzerland
Gut 52:886-92. 2003..The aim of this study was to evaluate if multi-detector row CT (MDCT) angiography contributes to the diagnosis of submucosal fundal varices...
- Endoscopy critics vs. endoscopy enthusiasts for primary prophylaxis of variceal bleedingRoberto de Franchis
Hepatology 43:24-6. 2006
- Portal hypertensive gastropathy in chronic hepatitis C patients with bridging fibrosis and compensated cirrhosis: results from the HALT-C trialRobert J Fontana
Division of Gastroenterology, University of Michigan Medical Center, Ann Arbor, Michigan, USA
Am J Gastroenterol 101:983-92. 2006....
- Esophageal variceal ligation for acute variceal bleeding: results of three years' follow-upEngin Altintas
Division of Gastroenterology, School of Medicine, Mersin University, Mersin, Turkey
Turk J Gastroenterol 15:27-33. 2004..However, the rebleeding course and long-term outcome of patients with esophageal variceal hemorrhage after ligation have been poorly defined. Therefore, we conducted a long-term follow-up study to delineate the outcome of ligation...
- Alcohol consumption by cirrhotic subjects: patterns of use and effects on liver functionMichael R Lucey
Department of Medicine, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin 53792 5124, USA
Am J Gastroenterol 103:1698-706. 2008....
- Balloon-occluded retrograde transvenous obliteration for gastric varices: the relationship between the clinical outcome and gastrorenal shunt occlusionKenichi Katoh
Department of Radiology, Iwate Medical University, Morioka, Japan
BMC Med Imaging 10:2. 2010..The purpose of this study is to retrospectively evaluate the technical aspects of B-RTO and the recurrence of gastric varices after treatment with this procedure...
- A standardized injection technique and regimen ensures success and safety of N-butyl-2-cyanoacrylate injection for the treatment of gastric fundal varices (with videos)Stefan Seewald
Department of Interdisciplinary Endoscopy, University Medical Center Hamburg Eppendorf, Hamburg, Germany
Gastrointest Endosc 68:447-54. 2008..N-butyl-2-cyanoacrylate has been successfully used for the treatment of bleeding from gastric fundal varices (FV). However, significant rebleeding rates and serious complications including embolism have been reported...
- Development of thrombus in the major systemic and portal veins after balloon-occluded retrograde transvenous obliteration for treating gastric variceal bleeding: its frequency and outcome evaluation with CTSung Ki Cho
Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Ilwon dong 50, Kangnam Gu, Seoul 135 710, Korea
J Vasc Interv Radiol 19:529-38. 2008....
- Balloon-occluded retrograde transvenous obliteration improves liver function in patients with cirrhosis and portal hypertensionYasunao Miyamoto
Department of Medicine II, Division of Gastroenterology and Endoscopy, Kurume University School of Medicine, Kurume, Japan
J Gastroenterol Hepatol 18:934-42. 2003..However, the effects of B-RTO on liver function remain unknown...
- Short-term complications of retrograde transvenous obliteration of gastric varices in patients with portal hypertension: effects of obliteration of major portosystemic shuntsR Shimoda
Gastroenterology Division, Maebashi Red Cross Hospital, Maebashi, Japan
Abdom Imaging 30:306-13. 2005..Thus, B-RTO is a safe and effective management of fundic varices. However, short-term hemodynamic change after B-RTO may cause gastric mucosal damage. Pulmonary infarction and pleural effusion are potential complications...
- Long-term results of balloon-occluded retrograde transvenous obliteration for gastric variceal bleeding and risky gastric varices: a 10-year experienceTomohiko Akahoshi
Departments of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
J Gastroenterol Hepatol 23:1702-9. 2008..We investigated the long-term effects of B-RTO on rebleeding, prevention of first bleeding, mortality and occurrence of risky esophageal varices (EVx)...
- External validation of the platelet count/spleen diameter ratio for the diagnosis of esophageal varices in hepatitis C virus-related cirrhosisAdnan Agha
Department of Internal Medicine, Medical Unit I, Jinnah Hospital, Allama Iqbal Medical College, Lahore, Pakistan
Dig Dis Sci 54:654-60. 2009..Screening for esophageal varices (EV) is an important part of the diagnostic workup of cirrhotic patients...
- Early detection in routine clinical practice of cirrhosis and oesophageal varices in chronic hepatitis C: comparison of transient elastography (FibroScan) with standard laboratory tests and non-invasive scoresLaurent Castera
Service d Hepato Gastroenterologie, Hopital Haut Leveque, Centre Hospitalier Universitaire CHU de Bordeaux, Pessac, France
J Hepatol 50:59-68. 2009....
- Clinical and laboratory predictors of esophageal varices in children and adolescents with portal hypertension syndromeEleonora Druve Tavares Fagundes
Department of Pediatrics, Hospital das Clinicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil
J Pediatr Gastroenterol Nutr 46:178-83. 2008..To determine the clinical and laboratory parameters that may predict the presence of esophageal varices in children and adolescents with portal hypertension...
- Recent variceal bleeding: Doppler US hepatic vein waveform in assessment of severity of portal hypertension and vasoactive drug responseSoon Koo Baik
Department of Internal Medicine, Yonsei University Wonju College of Medicine, 162 Ilsan dong, Wonju 220 701, South Korea
Radiology 240:574-80. 2006..To prospectively evaluate both the correlation between abnormal Doppler ultrasonography (US) hepatic vein waveforms and the hepatic venous pressure gradient (HVPG) and the response to drug treatment in patients with cirrhosis...
- The prevalence and risk factors associated with esophageal varices in subjects with hepatitis C and advanced fibrosisArun J Sanyal
Division of Gastroenterology, Virginia Commonwealth University Health System, Richmond, Virginia, USA
Gastrointest Endosc 64:855-64. 2006..The factors predictive of the presence or the absence of esophageal varices in hepatitis C virus (HCV) and advanced fibrosis have not been defined...
- Prevention and management of gastroesophageal varices and variceal hemorrhage in cirrhosisGuadalupe Garcia-Tsao
Section of Digestive Diseases, Yale University School of Medicine and VA CT Healthcare System, New Haven, Connecticut 06520, USA
Am J Gastroenterol 102:2086-102. 2007
- Diagnosis and monitoring of portal hypertensionR de Franchis
Department of Medical Sciences, University of Milan, Italy
Dig Liver Dis 40:312-7. 2008....
- Endoscopic ligation compared with combined treatment with nadolol and isosorbide mononitrate to prevent recurrent variceal bleedingC Villanueva
Department of Gastroenterology, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
N Engl J Med 345:647-55. 2001..We compared two treatments to prevent recurrent bleeding--endoscopic ligation and combined medical therapy with nadolol and isosorbide mononitrate...
- Platelet count/spleen diameter ratio: proposal and validation of a non-invasive parameter to predict the presence of oesophageal varices in patients with liver cirrhosisE Giannini
Gastroenterology Unit, Department of Internal Medicine, University of Genoa, Italy
Gut 52:1200-5. 2003....
- The use of self-expanding metal stents to treat acute esophageal variceal bleedingR Hubmann
2nd Dept of Internal Medicine, Linz General Hospital, Linz, Austria
Endoscopy 38:896-901. 2006..The primary aim of this study was to evaluate the use of self-expandable metallic stents to arrest uncontrollable acute variceal bleeding...
- Endoscopic variceal ligation plus propranolol versus endoscopic variceal ligation alone in primary prophylaxis of variceal bleedingShiv K Sarin
Department of Gastroenterology, G B Pant Hospital, New Delhi, India
Am J Gastroenterol 100:797-804. 2005..This prospective randomized controlled trial compared endoscopic variceal ligation (EVL) with propranolol and EVL alone in the prevention of first variceal bleed among patients with high-risk varices...
- The management of portal hypertension: rational basis, available treatments and future optionsJaime Bosch
Hepatic Hemodynamic Laboratory, Liver Unit, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, University of Barcelona, Hospital Clinic, C Villarroel 170, 08036 Barcelona, Spain
J Hepatol 48:S68-92. 2008....
- Influence of portal hypertension and its early decompression by TIPS placement on the outcome of variceal bleedingAlberto Monescillo
Digestive Disease Department, Hospital Universitario Insular de Gran Canaria, Canary Islands, Spain
Hepatology 40:793-801. 2004....
- Infection, coagulation, and variceal bleeding in cirrhosisU Thalheimer
Liver Transplantation and Hepatobiliary, Medicine Unit, Royal Free Hospital, Pond St, London NW3 2QG, UK
Gut 54:556-63. 2005
- Portal hypertension and variceal bleeding--unresolved issues. Summary of an American Association for the study of liver diseases and European Association for the study of the liver single-topic conferenceGuadalupe Garcia-Tsao
Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06520, USA
Hepatology 47:1764-72. 2008
- Predictors of esophageal varices in patients with HBV-related cirrhosis: a retrospective studyWan Dong Hong
Department of Gastroenterology and Hepatology, The First Affiliated Hospital of Wenzhou Medical College, Wenzhou, PR China
BMC Gastroenterol 9:11. 2009..Predicting the presence of EV through non-invasive means may reduce a large number of unnecessary endoscopies. This study was designed to develop a predictive model for varices in patients with Hepatitis B virus-related cirrhosis...
- Prediction of oesophagogastric varices in patients with liver cirrhosisF H Ng
Department of Medicine and Radiology, Ruttonjee Hospital, Hong Kong, China
J Gastroenterol Hepatol 14:785-90. 1999..All patients with liver cirrhosis are recommended for evaluation of oesophagogastric varices (EGV) regularly. This prospective study was designed to develop a predictive model for EGV in cirrhotic patients...
- Risk factors for the presence of varices in cirrhotic patients without a history of variceal hemorrhageA Zaman
Division of Gastroenterology and Hepatology, PV 310, Oregon Health Sciences University, 3181 Sam Jackson Park Rd, Portland, OR 97201, USA
Arch Intern Med 161:2564-70. 2001..The aim of this case-control study was to identify clinical, laboratory, and radiologic findings that predict the presence of varices in patients with cirrhosis...
- Treatment of esophageal varices: a randomized controlled trial comparing endoscopic sclerotherapy and EUS-guided sclerotherapy of esophageal collateral veinsGustavo Andrade de Paulo
Endoscopy Unit, Division of Gastroenterology, Universidade Federal de Sao Paulo UNIFESP EPM, Brazil
Gastrointest Endosc 63:396-402; quiz 463. 2006..Unfortunately, recurrence is common and seems to be related to esophageal collateral vessels, easily identified by EUS. Eradication of these vessels might lead to a more durable therapeutic effect...
- A randomized, controlled trial of medical therapy versus endoscopic ligation for the prevention of variceal rebleeding in patients with cirrhosisD Patch
Department of Liver Transplantation and Hepatobiliary Medicine, University Department of Surgery, Royal Free Hospital Hampstead NHS Trust, London, UK
Gastroenterology 123:1013-9. 2002..Since its introduction, endoscopic variceal banding has been shown to be superior to needle sclerotherapy. Banding has not been compared with hepatic venous pressure-guided medical therapy (beta-blockers and nitrates)...
- A self-expanding metal stent for complicated variceal hemorrhage: experience at a single centerGavin Wright
Sheila Sherlock Liver Centre, Royal Free Hospital, London, United Kingdom
Gastrointest Endosc 71:71-8. 2010..Existing salvage techniques such as transjugular intrahepatic portosystemic shunt (TIPS) and balloon tamponade (BT) have important limitations and may not be appropriate for all patients...
- Results of a new method to stop acute bleeding from esophageal varices: implantation of a self-expanding stentJ Zehetner
Surgical Department, Academic Teaching Hospital, AKH Linz, Ludwig Boltzmann Institute for Operative Laparoscopy, Krankenhausstrasse 9, 4020 Linz, Austria
Surg Endosc 22:2149-52. 2008..However, for 10% to 20% of patients, therapy fails to stop the bleeding. This study aimed to assess the SX-ELLA Stent Danis Set (which has a self-expanding metal stent) instead of a balloon probe for compression of esophageal varices...
- Distal splenorenal shunt versus transjugular intrahepatic portal systematic shunt for variceal bleeding: a randomized trialJ Michael Henderson
Department of Surgery, Cleveland Clinic, Cleveland, Ohio, USA
Gastroenterology 130:1643-51. 2006..This prospective randomized trial tested the hypothesis that patients receiving distal splenorenal shunts (DSRS) would have significantly lower rebleeding and encephalopathy rates than TIPS in management of refractory variceal bleeding...
- Prediction of oesophageal varices in hepatic cirrhosis by simple serum non-invasive markers: Results of a multicenter, large-scale studyGiada Sebastiani
Department of Digestive Diseases, Hepatology and Clinical Nutrition, Dell Angelo Hospital, Venice, Italy
J Hepatol 53:630-8. 2010..Preliminary data suggest that non-invasive methods could be useful to assess presence of oesophageal varices (OV) in cirrhotic patients. We aimed to further investigate simple serum non-invasive markers for diagnosing and grading OV...
- Review article: the modern management of portal hypertension--primary and secondary prophylaxis of variceal bleeding in cirrhotic patientsJ C Garcia-Pagan
Liver Unit, Hepatic Hemodynamic Laboratory, Hospital Clinic, IDIBAPS and Ciberehd, Barcelona, Spain
Aliment Pharmacol Ther 28:178-86. 2008..Variceal bleeding is a life-threatening complication of liver cirrhosis with a high probability of recurrence. Treatment to prevent first bleeding or rebleeding is mandatory...
- Pharmacological reduction of portal pressure and long-term risk of first variceal bleeding in patients with cirrhosisJuan Turnes
Hepatic Hemodynamic Laboratory, Liver Unit, Institut de Malalties Digestives, Hospital Clinic, IDIBAPS, University of Barcelona, Villaroel 170, 08036 Barcelona, Spain
Am J Gastroenterol 101:506-12. 2006..The aim of this study was to evaluate whether this protective effect is maintained in the long term and if it extends to other portal hypertension complications...
- Retrograde transvenous obliteration of gastric varices associated with large collateral veins or a large gastrorenal shuntKazuya Sugimori
Gastroenterological Center, Yokohama City University Medical Center, 4 57 Urafune cho, Minami Ku, Yokohama 232 0024, Japan
J Vasc Interv Radiol 16:113-8. 2005..There have been no complications or recurrences of gastric varices in any of the patients during the follow-up period...
- Noninvasive prediction of large esophageal varices in chronic liver disease patientsArulprakash Sarangapani
Department of Digestive Health and Diseases, Government Peripheral Hospital, Kilpauk Medical College, Chennai 102, India
Saudi J Gastroenterol 16:38-42. 2010..This prospective study was conducted to evaluate noninvasive predictors of large varices (LV)...
- Prophylactic endoscopic sclerotherapy of large esophagogastric varices in infants with biliary atresiaMathieu Duché
Division of Radiologie, Hopital Bicetre, Le Kremlin Bicetre, France
Gastrointest Endosc 67:732-7. 2008..Esophageal varices-related GI bleeding occurs frequently and early in life in children with biliary atresia and it may be life threatening...
- Therapeutic effect of balloon-occluded retrograde transvenous obliteration on portal-systemic encephalopathy in patients with liver cirrhosisT Kato
First Department of Internal Medicine, Gifu University School of Medicine
Intern Med 40:688-91. 2001..Additional B-RTO was required and effective in 2 of them. CONCLUSION: B-RTO is an effective treatment for chronic recurrent hepatic encephalopathy with an angiographically proven portal-systemic shunt...
- The role of transjugular intrahepatic portosystemic shunt (TIPS) in the management of portal hypertensionLuis Colombato
Hepatic Hemodynamic Section, Liver Unit, Gastroenterology Department, Buenos Aires British Hospital, Buenos Aires School of Medicine, Buenos Aires University, Buenos Aires, Argentina
J Clin Gastroenterol 41:S344-51. 2007..Pre-TIPS evaluation taking into account predictors of outcome is mandatory. The improved results achieved with covered-stents might expand the currently accepted recommendations for TIPS use...
- Percutaneous paraumbilical embolization as an unconventional and successful treatment for bleeding jejunal varicesLee Guan Lim
Department of Gastroenterology and Hepatology, National University Hospital, 5 Lower Kent Ridge Road, 119074, Singapore 119074, Singapore
World J Gastroenterol 15:3823-6. 2009..Percutaneous paraumbilical embolization via caput medusa was performed on day 9 of hospitalization. Following the embolization, the hematochezia stopped. However, he defaulted subsequent follow-up...
- Transcatheter obliteration of gastric varices: Part 2. Strategy and techniques based on hemodynamic featuresHiro Kiyosue
Department of Radiology, Oita Medical University, 1 1 Hasama, Oita 879 55, Japan
Radiographics 23:921-37; discussion 937. 2003..The majority of gastric varices can be treated successfully with a combination of these techniques. However, accurate assessment of the variceal hemodynamic pattern is the most important factor in ensuring successful treatment...
- Portal hypertension and variceal hemorrhageNagib Toubia
Division of Gastroenterology, Hepatology and Nutrition, Virginia Commonwealth University School of Medicine, MCV, Box 980341, Richmond, VA 23298 0341, USA
Med Clin North Am 92:551-74, viii. 2008....
- Incidence and prevalence of cirrhosis in the United Kingdom, 1992-2001: a general population-based studyKate M Fleming
Division of Epidemiology and Public Health, University of Nottingham, Nottingham, UK
J Hepatol 49:732-8. 2008..To determine the incidence and prevalence of cirrhosis in the United Kingdom...
- Prediction of large esophageal varices in patients with cirrhosis of the liver using clinical, laboratory and imaging parametersSanjay Kumar Sharma
Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India
J Gastroenterol Hepatol 22:1909-15. 2007..This approach leads to unnecessary UGIE in those without LEVx. We tried to identify clinical, laboratory and imaging parameters that may predict the presence of LEVx and help select patients for UGIE...
- Platelet count is not a predictor of the presence or development of gastroesophageal varices in cirrhosisAmir A Qamar
Brigham and Women s Hospital, Boston, MA 02446, USA
Hepatology 47:153-9. 2008..0374). A significant correlation was found between HVPG and PLT at the baseline, year 1, and year 5 (P < 0.0001)...
- HCV-HIV Coinfection: Impact of Immune DysfunctionRichard Sterling; Fiscal Year: 2007..The K-23 award will protect this candidates time and help him mature into a senior investigator in Hepatology. ..
- UGI Hemorrhage and Barrett's EpitheliumDennis Jensen; Fiscal Year: 2008..This award will continue to enhance the applicant's research productivity and provide skilled mentoring for young investigators, so they can become independent patient-oriented investigators in digestive diseases. ..
- MULTICENTER RANDOMIZED TRIAL OF DSRS VERSUS TIPSJohn Henderson; Fiscal Year: 2004..The extension of this trial, will provide the most comprehensive and longest follow-up for these two shunt procedures for control of variceal bleeding. ..
- Relationship of metabolic abnormalities to hepatic steatosis in HIVRichard Sterling; Fiscal Year: 2008..If our hypothesis is correct, this work could result in a dramatic change in the long-term care of the over 1 million HIV infected individuals in the US. [unreadable] [unreadable]..
- Biliary Microlithiasis in Alcohol Induced PancreatitisArun Sanyal; Fiscal Year: 2007..The long-term goal is to use data from this R21 proposal to develop a RO1 proposal about a large scale phase III clinical trial of UDCA for alcohol-induced pancreatitis. [unreadable] [unreadable] [unreadable]..
- NO production and S-nitrosylation in liver vasculatureYasuko Iwakiri; Fiscal Year: 2008..The School of Medicine has pledged protected time for the candidate during this further training period prior to functioning as an independent investigator. ..
- Molecular Mechanisms of Portal HypertensionVijay Shah; Fiscal Year: 2007..abstract_text> ..
- FACTORS IN THE PREVENTION OF TOXIC LIVER INJURYThomas Boyer; Fiscal Year: 2008..The studies will clarify why expression of certain proteins fall during the acute phase response. ..
- REG OF NITRIC OXIDE PRODUCT IN THE HEPATIC CIRCULATIONVijay Shah; Fiscal Year: 2002..Defining the mechanisms that regulate nitric oxide production in SEC may lead to therapeutic options whereby NO activity may be pharmacologically or genetically modulated and benefit patients with cirrhosis and portal hypertension. ..
- Artificial Nutrition in Terminally Ill Cancer PatientsSydney Dy; Fiscal Year: 2007..Dy with the skills she needs to develop into an independent clinical researcher in oncology palliative care decision-making and health services research. ..
- Failure of FasL Mediated Pathways in Tumor AngiogenesisVijay Shah; Fiscal Year: 2006..These insights may lead to novel and effective therapeutic strategies that target this pathway to prevent angiogenesis, and thereby prevent colorectal tumor development growth and spread. ..
- Inhibition of TNF in Patients with Alcoholic HepatitisVijay Shah; Fiscal Year: 2005..abstract_text> ..
- Endothelial Nitric Oxide Synthase & Portal HypertensionVijay Shah; Fiscal Year: 2002..abstract_text> ..
- Pathophysiological Interpretations of Dynamic PET/CT of Molecular Liver BiologySusanne Keiding; Fiscal Year: 2010..This will lead to improved diagnosis and treatment of the large groups of patients with liver disease and cancer in the liver. ..