rectal fistula

Summary

Summary: An abnormal anatomical passage connecting the RECTUM to the outside, with an orifice at the site of drainage.

Top Publications

  1. ncbi Outcomes of primary repair of anorectal and rectovaginal fistulas using the endorectal advancement flap
    Toyooki Sonoda
    Department of Colorectal Surgery, The Cleveland Clinic Foundation, Ohio, USA
    Dis Colon Rectum 45:1622-8. 2002
  2. ncbi Fibrin glue treatment of complex anal fistulas has low success rate
    Rasmy Loungnarath
    Section of Colon and Rectal Surgery, Washington University School of Medicine Barnes Jewish Hospital, St Louis, Missouri, USA
    Dis Colon Rectum 47:432-6. 2004
  3. ncbi Effect of tobacco smoking on advancement flap repair of complex anal fistulas
    C Neal Ellis
    Department of Surgery, University of South Alabama, 2451 Fillingim St, MSTN 706, Mobile, Alabama, 36617, USA
    Dis Colon Rectum 50:459-63. 2007
  4. ncbi Gracilis muscle interposition for the treatment of rectourethral, rectovaginal, and pouch-vaginal fistulas: results in 53 patients
    Steven D Wexner
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida 33331, USA
    Ann Surg 248:39-43. 2008
  5. ncbi Tract length predicts successful closure with anal fistula plug in cryptoglandular fistulas
    Michael F McGee
    Department of Surgery, Division of Colorectal Surgery, University Hospitals of Cleveland Case Medical Center, Cleveland, Ohio 44106, USA
    Dis Colon Rectum 53:1116-20. 2010
  6. pmc Seton drainage prior to transanal advancement flap repair: useful or not?
    Litza E Mitalas
    Colorectal Research Group, Department of Surgery, Erasmus Medical Center, H 181 s Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands
    Int J Colorectal Dis 25:1499-502. 2010
  7. ncbi Anal lesion resulting from implantation of viable tumour cells in a pre-existing anal fistula. A case report
    G Kouraklis
    2nd Department of Propedeutic Surgery, Medical School of Athens University, Athens, Greece
    Acta Chir Belg 102:212-3. 2002
  8. ncbi Adenocarcinoma of the rectosigmoid colon seeding into pre-existing anal fistula
    Kazuo Wakatsuki
    Department of Surgery, Chiba Municipal Kaihin Hospital, Mihama ku, Chiba City, Chiba, 261 0012, Japan
    Hepatogastroenterology 55:952-5. 2008
  9. ncbi Fibrin glue for the treatment of fistulae in ano--a method worth sticking to?
    J M C Yeung
    Department of Colorectal Surgery, Peter MacCallum Cancer Unit, Melbourne, Australia
    Colorectal Dis 12:363-6. 2010
  10. ncbi Changes in anorectal morphologic and functional parameters after fistula-in-ano surgery
    José V Roig
    Unidad de Coloproctologia, Servicio de Cirugía General y Digestiva, Consorcio Hospital General Universitario de Valencia, Valencia, Spain
    Dis Colon Rectum 52:1462-9. 2009

Research Grants

Detail Information

Publications217 found, 100 shown here

  1. ncbi Outcomes of primary repair of anorectal and rectovaginal fistulas using the endorectal advancement flap
    Toyooki Sonoda
    Department of Colorectal Surgery, The Cleveland Clinic Foundation, Ohio, USA
    Dis Colon Rectum 45:1622-8. 2002
    ..This study was undertaken to examine the success rate of primary endorectal advancement flap in our own institution. We attempted to identify factors that influence the rate of healing...
  2. ncbi Fibrin glue treatment of complex anal fistulas has low success rate
    Rasmy Loungnarath
    Section of Colon and Rectal Surgery, Washington University School of Medicine Barnes Jewish Hospital, St Louis, Missouri, USA
    Dis Colon Rectum 47:432-6. 2004
    ..Reported success rates vary widely. The purpose of this study was to review the use of fibrin glue in the management of complex anal fistulas at a tertiary referral center...
  3. ncbi Effect of tobacco smoking on advancement flap repair of complex anal fistulas
    C Neal Ellis
    Department of Surgery, University of South Alabama, 2451 Fillingim St, MSTN 706, Mobile, Alabama, 36617, USA
    Dis Colon Rectum 50:459-63. 2007
    ..This study was performed to evaluate our results with advancement flap repair of anal fistulas and to identify factors associated with failure...
  4. ncbi Gracilis muscle interposition for the treatment of rectourethral, rectovaginal, and pouch-vaginal fistulas: results in 53 patients
    Steven D Wexner
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida 33331, USA
    Ann Surg 248:39-43. 2008
    ..The aim of this study was to review our experience with gracilis muscle interposition for complex perineal fistulas...
  5. ncbi Tract length predicts successful closure with anal fistula plug in cryptoglandular fistulas
    Michael F McGee
    Department of Surgery, Division of Colorectal Surgery, University Hospitals of Cleveland Case Medical Center, Cleveland, Ohio 44106, USA
    Dis Colon Rectum 53:1116-20. 2010
    ..Collagen anal fistula plug treatment of transsphincteric fistulas produces variable results. The purpose of our study was to determine whether long-tract fistulas (>4 cm) correlated with successful closure...
  6. pmc Seton drainage prior to transanal advancement flap repair: useful or not?
    Litza E Mitalas
    Colorectal Research Group, Department of Surgery, Erasmus Medical Center, H 181 s Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands
    Int J Colorectal Dis 25:1499-502. 2010
    ..We conducted the present study to assess the influence of preoperative seton drainage on the outcome of TAFR in a relatively large series...
  7. ncbi Anal lesion resulting from implantation of viable tumour cells in a pre-existing anal fistula. A case report
    G Kouraklis
    2nd Department of Propedeutic Surgery, Medical School of Athens University, Athens, Greece
    Acta Chir Belg 102:212-3. 2002
    ..In conclusion, surgeons should be aware of the possibility of cancer spread incidence, distally beyond the initial site by exfoliated cancer cells into the lumen of the bowel...
  8. ncbi Adenocarcinoma of the rectosigmoid colon seeding into pre-existing anal fistula
    Kazuo Wakatsuki
    Department of Surgery, Chiba Municipal Kaihin Hospital, Mihama ku, Chiba City, Chiba, 261 0012, Japan
    Hepatogastroenterology 55:952-5. 2008
    ..Furthermore, immunohistochemistry for cytokeratins 7 and 20 was performed on tissues to distinguish colorectal adenocarcinoma from anal gland carcinoma. Both colorectal cancer and perianal tumor showed CK7-/CK20+...
  9. ncbi Fibrin glue for the treatment of fistulae in ano--a method worth sticking to?
    J M C Yeung
    Department of Colorectal Surgery, Peter MacCallum Cancer Unit, Melbourne, Australia
    Colorectal Dis 12:363-6. 2010
    ..This study reviews the experience of fibrin glue as a treatment for anal fistulae in a single tertiary referral centre and attempts to identify factors related to failure of therapy and the length of follow-up required...
  10. ncbi Changes in anorectal morphologic and functional parameters after fistula-in-ano surgery
    José V Roig
    Unidad de Coloproctologia, Servicio de Cirugía General y Digestiva, Consorcio Hospital General Universitario de Valencia, Valencia, Spain
    Dis Colon Rectum 52:1462-9. 2009
    ..This study aimed to analyze changes in anal continence and morphologic and functional anorectal variables after fistula-in-ano surgery in a patient series with a high rate of complex fistulas...
  11. ncbi Fistulotomy with primary sphincter reconstruction in the management of complex fistula-in-ano: prospective study of clinical and manometric results
    Francisco Perez
    Coloproctology Unit, Department of Surgery, University Hospital of Elche C Huertos y Molinos s n, Elche Alicante, Spain
    J Am Coll Surg 200:897-903. 2005
    ..The objective of this study was to assess the results of fistulotomy with sphincter reconstruction in terms of recurrence and anal function...
  12. ncbi Does rectal mucosal blood flow affect the outcome of transanal advancement flap repair?
    Litza E Mitalas
    Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
    Dis Colon Rectum 52:1395-9. 2009
    ..We postulated that impaired blood flow might result in breakdown of the distal part of the flap. This study was designed to evaluate the effect of rectal mucosal blood flow on the outcome of transanal advancement flap repair...
  13. ncbi The efficacy of anal fistula plug in fistula-in-ano: a systematic review
    P Garg
    Department of General Surgery, Fortis Super Specialty Hospital, Mohali, Punjab, India
    Colorectal Dis 12:965-70. 2010
    ..To assess the efficacy of anal fistula plug (AFP) procedure for the treatment of fistula-in-ano especially the complex fistulas...
  14. ncbi Ligation of the intersphincteric fistula tract (LIFT) to treat anal fistula: early results from a prospective observational study
    P Sileri
    Department of Surgery, University of Rome Tor Vergata, Policlinico Tor Vergata, Chirurgia Generale 6B, Viale Oxford 81, 00133 Rome, Italy
    Tech Coloproctol 15:413-6. 2011
    ..Literature data are still scant. In this prospective observational study, we present our experience with this technique...
  15. ncbi A case of rectosigmoid cancer metastasizing to a fistula in ano
    Madoka Hamada
    Department of Surgery, Kochi Health Sciences Center, Kochi 781 855, Japan
    Jpn J Clin Oncol 35:676-9. 2005
    ..We diagnosed this tumor as metastatic adenocarcinoma from a rectosigmoid cancer. Recurrent lesions were not seen during the first year after the first operation...
  16. ncbi Histological identification of epithelium in perianal fistulae: a prospective study
    P J van Koperen
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    Colorectal Dis 12:891-5. 2010
    ..The aim of this study was to assess the incidence and origin of epithelialization of the fistula tract in patients with perianal fistulae undergoing fistulotomy...
  17. ncbi Anal fistula plug: initial experience and outcomes
    Bashar Safar
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida, USA
    Dis Colon Rectum 52:248-52. 2009
    ..This study was designed to analyze the efficacy of the Cook Surgisis AFP anal fistula plug for the management of complex anal fistulas...
  18. ncbi Gore Bio-A® Fistula Plug: a new sphincter-sparing procedure for complex anal fistula
    C Ratto
    Department of Surgical Sciences, Catholic University, Rome, Italy
    Colorectal Dis 14:e264-9. 2012
    ..The Gore Bio-A® Fistula Plug is a new bioprosthetic plug that has been proposed for the treatment of complex anal fistula. This study reports preliminary data following implantation of this plug...
  19. ncbi Synchronous carcinoma of the sigmoid colon and a perianal fistula
    Andrew P Zbar
    Dis Colon Rectum 47:544-5; author reply 545. 2004
  20. ncbi Experimental model of fistula-in-ano
    Gordon N Buchanan
    Department of Surgery, St Mark s Hospital, Harrow, United Kingdom
    Dis Colon Rectum 48:353-8. 2005
    ..This study was designed to create and evaluate an experimental porcine model of fistula-in-ano...
  21. ncbi Colosigmoid adenocarcinoma anastomotic recurrence seeding into a transsphincteric fistula-in-ano: a clinical report and literature review
    Gianpiero Gravante
    General Surgery Department, University of Rome Tor Vergata, Rome, Italy
    Surg Laparosc Endosc Percutan Tech 18:407-8. 2008
    ....
  22. ncbi The anal fistula plug treatment compared with the mucosal advancement flap for cryptoglandular high transsphincteric perianal fistula: a double-blinded multicenter randomized trial
    Paul J van Koperen
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    Dis Colon Rectum 54:387-93. 2011
    ..The anal fistula plug was developed as an alternative treatment for perianal fistulas...
  23. ncbi Evaluation of a new synthetic plug in the treatment of anal fistulas: results of a pilot study
    Fernando de la Portilla
    Coloproctology Unit, University Hospital Virgen del Rocio, Seville, Spain
    Dis Colon Rectum 54:1419-22. 2011
    ..If unsuccessful, it does not compromise subsequent alternative surgical techniques and/or products. However, success rates are variable...
  24. ncbi Endorectal advancement flaps in the treatment of high anal fistula of cryptoglandular origin: full-thickness vs. mucosal-rectum flaps
    Peter C Dubsky
    Department of General Surgery, Vienna Medical School, Waehringerguertel 18 20, A 1090, Vienna, Austria
    Dis Colon Rectum 51:852-7. 2008
    ..A comparison between full-thickness flaps and mucosal (partial-thickness) flaps was made to analyze the defining elements of successful fistula treatment: recurrence rates and anal continence...
  25. ncbi Treatment of transsphincteric anal fistulas by endorectal advancement flap or collagen fistula plug: a comparative study
    Dimitrios Christoforidis
    Division of Colon and Rectal Surgery, Department of Surgery, University of Minnesota Medical School, Minneapolis, USA
    Dis Colon Rectum 52:18-22. 2009
    ..In this study we compared the outcomes of patients with complex cryptoglandular fistulas treated by endorectal advancement flap or anal fistula plug...
  26. ncbi Efficacy of anal fistula plug vs. fibrin glue in closure of anorectal fistulas
    Eric K Johnson
    Georgia Colon and Rectal Surgical Clinic, Atlanta, Georgia 30342, USA
    Dis Colon Rectum 49:371-6. 2006
    ..A suturable bioprosthetic plug (Surgisis, Cook Surgical, Inc.) was fashioned to close the primary opening of fistula tracts. A prospective cohort study was performed to compare fibrin glue vs. the anal fistula plug...
  27. ncbi Implantation of rectal cancer in an anal fistula: report of a case
    Satoshi Ishiyama
    Deparment of Surgery, Jikei University School of Medicine, Minato ku, Tokyo 105 8461, Japan
    Surg Today 36:747-9. 2006
    ..Although the recurrence of rectal cancer by mucosal implantation is not uncommon, the coincidental implantation of rectal cancer in an anal fistula is extremely rare...
  28. ncbi Randomized clinical and manometric study of advancement flap versus fistulotomy with sphincter reconstruction in the management of complex fistula-in-ano
    Francisco Perez
    Coloproctology Unit, Department of Surgery, University Hospital of Elche, C Huertos y Molinos s n, 03202 Elche, Alicante, Spain
    Am J Surg 192:34-40. 2006
    ..The goal of this study was to compare the outcomes of advancement flap (AF) versus fistulotomy with sphincter reconstruction (FSR) for primary complex fistula-in-ano in terms of recurrence and anal function...
  29. pmc Implantation metastasis from adenocarcinoma of the colon into a fistula-in-ano: a case report
    Rohit Gupta
    Centre for Minimal Access Surgery, St Joseph Hospital, McMaster University, Hamilton, Ont
    Can J Surg 48:162-3. 2005
  30. ncbi Incontinence rates after cutting seton treatment for anal fistula
    R D Ritchie
    RDRR Biotech Consulting, Lafayette, Indiana, USA
    Colorectal Dis 11:564-71. 2009
    ..To determine the incidence of anal incontinence after the use of cutting seton treatment for anal fistula...
  31. ncbi A tale of two (anal fistula) plugs: is there a difference in short-term outcomes?
    Brian Buchberg
    University of California Irvine Medical Center, Orange, California, USA
    Am Surg 76:1150-3. 2010
    ..Patients should be cautioned regarding potentially high failure rates; however, longer follow-up and a larger patient population are needed to confirm significant differences in fistula plug efficacy...
  32. ncbi Smoking impairs rectal mucosal bloodflow--a pilot study: possible implications for transanal advancement flap repair
    David D E Zimmerman
    Colorectal Research Group of Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
    Dis Colon Rectum 48:1228-32. 2005
    ..018; Mann-Whitney). In conclusion, it seems likely that impaired wound healing caused by a diminished rectal mucosal perfusion is a contributing factor in the breakdown of advancement flaps in patients who smoke cigarettes...
  33. ncbi Surgical management of anal fistulae: a systematic review
    A I Malik
    Colorectal Unit, Department of Surgery, Northern General Hospital, Sheffield, UK
    Colorectal Dis 10:420-30. 2008
    ..We aimed to systematically review the available studies relating to the surgical management of anal fistulas...
  34. ncbi Early experience with the bioabsorbable anal fistula plug
    D A Lawes
    Division of Colorectal Surgery, Mayo Clinic, 5777 East Mayo Boulevard, Phoenix, Arizona 85054, USA
    World J Surg 32:1157-9. 2008
    ..Recent reports of the results of the porcine anal fistula plug have demonstrated excellent fistula healing rates without reporting significant complications...
  35. ncbi The direct closure of the internal fistula opening without advancement flap for transsphincteric fistulas-in-ano
    Sotirios Athanasiadis
    Department of Coloproctology, St Joseph Hospital Duisburg Laar, Ahrstrabetae 100, D 47139, Duisburg, Germsny
    Dis Colon Rectum 47:1174-80. 2004
    ..The authors hypothesize that a direct closure of the internal fistula opening without tissue mobilization is easier to facilitate and generally leads to better clinical and functional results...
  36. ncbi Treatment of fistulas in ano with fibrin glue
    Suzanne S Gisbertz
    Department of Surgery, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Dig Surg 22:91-4. 2005
    ..The aim of this pilot study was to analyse if we could reproduce the results reported in the literature, using this simple technique...
  37. ncbi Antimicrobial peptides in chronic anal fistula epithelium
    Karlheinz Kiehne
    I Department of Internal Medicine, Universitatsklinikum Schleswig Holstein, Schittenhelmstr, Germany
    Scand J Gastroenterol 42:1063-9. 2007
    ..The aim of this study was to investigate whether epithelium is present in the fistulas and what the origin might be...
  38. ncbi Required length of follow-up after transanal advancement flap repair of high transsphincteric fistulas
    L E Mitalas
    Department of Surgery, Erasmus Medical Centre Rotterdam, Rotterdam, The Netherlands
    Colorectal Dis 11:726-8. 2009
    ..More recent studies indicate that TAFR fails in one out of three patients. The aim of the present study was to determine the appropriate length of follow-up needed to assess the healing rate after TAFR of high transsphincteric fistulas...
  39. ncbi Fistula-associated anal adenocarcinoma in Crohn's disease
    Igors Iesalnieks
    Department of Surgery, University of Regensburg, Germany
    Inflamm Bowel Dis 16:1643-8. 2010
    ..We present 6 patients with CD and fistula-associated anal adenocarcinoma (FAAA) and a systematic review of published series...
  40. ncbi For many high anal fistulas, lay open is still a good option
    G K Atkin
    St Mark s Hospital, Watford Rd, Harrow, Middlesex, HA1 3UJ, UK
    Tech Coloproctol 15:143-50. 2011
    ..Optimal treatment for high/complex anal fistulas is uncertain. We have studied one surgeon's results over a ten-year period, concentrating on high fistulas...
  41. ncbi Endorectal advancement flap: are there predictors of failure?
    Nelly Mizrahi
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, USA
    Dis Colon Rectum 45:1616-21. 2002
    ..The aim of this study was to review our experience with endorectal advancement flap in the treatment of complex perianal fistulas and to define the predictors of successful healing...
  42. pmc Cryptoglandular anal fistulas
    Andreas Ommer
    End und Dickdarmpraxis Essen, Germany
    Dtsch Arztebl Int 108:707-13. 2011
    ..Cryptoglandular anal fistula arises in 2 per 10 000 persons per year and is most common in young men. Improper treatment can result in fecal incontinence and thus in impaired quality of life...
  43. ncbi Seton or glue for trans-sphincteric anal fistulae: a prospective randomized crossover clinical trial
    D F Altomare
    Department of Emergency and Organ Transplantation, University of Bari, Italy
    Colorectal Dis 13:82-6. 2011
    ....
  44. ncbi Fibrin glue-antibiotic mixture in the treatment of anal fistulae: experience with 69 cases
    L Patrlj
    Department of Abdominal Surgery, University Hospital Merkur, Zagreb, Republic of Croatia
    Dig Surg 17:77-80. 2000
    ..To investigate the potential value of the use of the fibrin glue-antibiotic mixture in the treatment of anal fistulae...
  45. ncbi [Epidermoid carcinoma developing in a chronic anal fistula]
    B Abboud
    Service de Chirurgie Generale, Hotel Dieu de France, Faculté de Médecine Université Saint Joseph, Beyrouth, Liban
    Presse Med 29:786-7. 2000
    ..Malignant degeneration of anal fistula is a rare occurrence in the course of a common disease. Abdominoperineal resection offers the only hope of cure...
  46. ncbi Smoking affects the outcome of transanal mucosal advancement flap repair of trans-sphincteric fistulas
    D D E Zimmerman
    Department of Surgery, Erasmus Medical Centre, Rotterdam, The Netherlands
    Br J Surg 90:351-4. 2003
    ..The aim of the study was to identify variables affecting the outcome of transanal advancement flap repair (TAFR) for perianal fistulas of cryptoglandular origin...
  47. pmc Repeat transanal advancement flap repair: impact on the overall healing rate of high transsphincteric fistulas and on fecal continence
    Litza E Mitalas
    Colorectal Research Group Rotterdam, Department of Surgery, Erasmus Medical Center, Rotterdam, The Netherlands
    Dis Colon Rectum 50:1508-11. 2007
    ..The purpose of the present study was to evaluate the success rate of a repeat TAFR and to assess the impact of such a second procedure on the overall healing rate of high transsphincteric fistulas and on fecal continence...
  48. ncbi Treatment of complex anal fistulas with the collagen fistula plug
    Dimitrios Christoforidis
    Division of Colon and Rectal Surgery, Department of Surgery, University of Minnesota Medical School, Minneapolis, Minnesota, USA
    Dis Colon Rectum 51:1482-7. 2008
    ..In this study, we evaluated our experience with the Surgisis anal fistula plug, which was recently reported to be successful in >80 percent of patients with complex fistulas...
  49. ncbi Fibrin glue sealing in the treatment of perineal fistulas
    Oded Zmora
    Department of Colorectal Surgery, Cleveland Clinic Florida, Weston, Florida 33331, USA
    Dis Colon Rectum 46:584-9. 2003
    ..Fibrin glue may close fistula tracts without muscle division. Therefore, the aim of this study was to evaluate the use of fibrin glue sealing in treatment of perineal fistulas...
  50. ncbi Fibrin glue for anal fistulas: long-term results
    Stephen M Sentovich
    Section of Colon and Rectal Surgery, Department of Surgery, Boston University School of Medicine, Boston, MA, USA
    Dis Colon Rectum 46:498-502. 2003
    ..The aim of this study was to evaluate the long-term success and complication rate of fibrin-glue treatment of anal fistulas...
  51. ncbi Routine use of setons for the treatment of anal fistulae
    A Theerapol
    Department of Surgery, National University Hospital, Singapore
    Singapore Med J 43:305-7. 2002
    ..Anal fistula is usually treated by either fistulotomy or fistulectomy. We described the routine use of setons to treat anal fistula without any surgery...
  52. ncbi Length of follow-up after fistulotomy and fistulectomy associated with endorectal advancement flap repair for fistula in ano
    H Ortiz
    Unit of Coloproctology, Department of Surgery, Hospital Virgen del Camino, Universidad Publica de Navarra, Pamplona, Spain
    Br J Surg 95:484-7. 2008
    ..This prospective study determined the follow-up time needed to establish that an anal fistula has been cured after elective fistulotomy or fistulectomy associated with endorectal advancement flap (ERAF) repair...
  53. ncbi Fibrin glue in the management of anal fistulae
    T M Hammond
    Centre for Academic Surgery, Institute of Cell and Molecular Science, Barts and The London, Queen Mary School of Medicine and Dentistry, London, UK
    Colorectal Dis 6:308-19. 2004
    ..The objective of this review was to ascertain the role of fibrin glue in the management of anal fistulae, including assessment of recurrence rates, continence disturbance and other complications...
  54. ncbi Initial experience on efficacy in closure of cryptoglandular and Crohn's transsphincteric fistulas by the use of the anal fistula plug
    O Schwandner
    Department of Surgery, Pelvic Floor Center Regensburg, Caritas Krankenhaus St Josef, Landshuter Str 65, 93053 Regensburg, Germany
    Int J Colorectal Dis 23:319-24. 2008
    ..It was the aim of this prospective study to analyze the efficacy of the Cook Surgisis AFP anal fistula plug (AFP) for the closure of cryptoglandular and Crohn's disease-associated transsphincteric anorectal fistulas...
  55. ncbi Surgery for fistula-in-ano: an audit of practise of colorectal and general surgeons
    N Nwaejike
    Department of Surgery, Altnagelvin Hospital, Londonderry, UK
    Colorectal Dis 9:749-53. 2007
    ....
  56. ncbi Meta-analysis of randomized clinical trials comparing drainage alone vs primary sphincter-cutting procedures for anorectal abscess-fistula
    H M Quah
    Department of Colorectal Surgery, Singapore General Hospital, Outram Road, Singapore, 169608, Republic of Singapore
    Int J Colorectal Dis 21:602-9. 2006
    ..This meta-analysis was conducted to determine the merits of drainage alone vs primary sphincter-cutting procedures (which includes fistulotomy and fistulectomy) for anorectal abscess-fistula...
  57. ncbi Treatment of fistula-in-ano with the Surgisis(®) AFP(TM) anal fistula plug
    R M Lupinacci
    Service de Chirurgie Generale et Digestive, Hopital Saint Antoine, AP HP, Universite Pierre et Marie Curie, Paris VI, 184 rue du Faubourg Saint Antoine, Paris Cedex 12, France
    Gastroenterol Clin Biol 34:549-53. 2010
    ..Closure of the fistula tract with an anal fistula plug has been reported to provide success rates as high as 80%. The purpose of this study was to evaluate our results with this new method...
  58. ncbi Controlled, randomized trial of island flap anoplasty for treatment of trans-sphincteric fistula-in-ano: early results
    K S Ho
    Department of Colorectal Surgery, Singapore General Hospital, Singapore
    Tech Coloproctol 9:166-8. 2005
    ..IFA is a safe and useful method for treating transsphincteric fistula. It can be considered when a suprasphincteric extension is suspected, thus avoiding risk of incontinence or the discomfort of a long-term seton...
  59. ncbi Randomized clinical trial of local gentamicin-collagen treatment in advancement flap repair for anal fistula
    U M Gustafsson
    Department of Surgery, University Hospital, S 751 85 Uppsala, Sweden
    Br J Surg 93:1202-7. 2006
    ..A possible cause of non-healing is local infection of the flap. The aim of this study was to evaluate whether local antibiotic treatment with gentamicin-collagen improves healing after endoanal advancement flap repair for anal fistula...
  60. ncbi Conventional cutting vs. internal anal sphincter-preserving seton for high trans-sphincteric fistula: a prospective randomized manometric and clinical trial
    A P Zbar
    Department of Surgery, Queen Elizabeth Hospital, University of the West Indies, Martindales Road, St Michael, Barbados
    Tech Coloproctol 7:89-94. 2003
    ..The aim of this study was to compare a modified cutting seton, which repaired the internal anal sphincter muscle and re-routed the seton through the intersphincteric space, with a conventional cutting seton...
  61. ncbi Malignant transformation in perianal fistulas of Crohn's disease: a systematic review of literature
    Mathew Thomas
    Department of Surgery, Robert Packer Hospital Guthrie Clinic, Sayre, PA 18840, USA
    J Gastrointest Surg 14:66-73. 2010
    ..Malignant transformation of perineal fistula in Crohn's disease has rarely been reported. The aim of this study is to define the patient's characteristics and clinical presentation of this rare disease...
  62. ncbi A case of large mucinous adenocarcinoma arising in a long-standing fistula-in-ano
    Yamac Erhan
    Department of Surgery, Celal Bayar University Faculty of Medicine, Manisa, Turkey
    Dig Surg 20:69-71. 2003
    ..Chronic anal fistulas are not rare conditions, however, the development of a carcinoma in a long-standing fistula-in-ano is rare...
  63. ncbi To plug or not to plug: a cost-effectiveness analysis for complex anal fistula
    Michel Adamina
    Department of Surgery, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
    Surgery 147:72-8. 2010
    ..This study aims to evaluate the cost-effectiveness of the AFP compared to the endoanal advancement flap (EAAF) as an alternative sphincter-preserving option for complex anal fistulas...
  64. ncbi Direct appositional (no flap) closure of deep anal fistula
    W H F Thomson
    Gloucestershire Royal Hospital, Gloucester, UK
    Colorectal Dis 6:32-6. 2004
    ..Our own method having for many years been simple appositional closure the resulting series presented an opportunity for comparison...
  65. ncbi Ligation of the intersphincteric fistula tract (LIFT): a sphincter-saving technique for fistula-in-ano
    A Shanwani
    Department of Surgery, Hospital Raja Perempuan Zainab II, Kota Bharu, Kelantan, Malaysia
    Dis Colon Rectum 53:39-42. 2010
    ..This study was designed to assess the total anal sphincter-saving technique of ligating the intersphincteric fistula tract for the treatment of fistula-in-ano...
  66. ncbi Treatment of transsphincteric anal fistulas: are fistula plugs an acceptable alternative?
    Jennifer Y Wang
    Department of Surgery, University of California, San Francisco, San Francisco, California, USA
    Dis Colon Rectum 52:692-7. 2009
    ..To examine the benefit of the anal fistula plug, we compared its success rate with a standard treatment for transsphincteric fistulas with similar indications, the transanal mucosal advancement flap...
  67. ncbi Long-term outcome following mucosal advancement flap for high perianal fistulas and fistulotomy for low perianal fistulas: recurrent perianal fistulas: failure of treatment or recurrent patient disease?
    S J van der Hagen
    Department of Surgery, Academic Hospital Maastricht, Maastricht, The Netherlands
    Int J Colorectal Dis 21:784-90. 2006
    ..In this study, we determined the long-term outcome of perianal fistulas treated with mucosal advancement flap (MF) or fistulotomy (FT)...
  68. ncbi Fibrin glue as an adjunct to flap repair of anal fistulas: a randomized, controlled study
    C Neal Ellis
    Department of Surgery, University of South Alabama, 2451 Fillingim Street, MSTN 706, Mobile, AL 36617, USA
    Dis Colon Rectum 49:1736-40. 2006
    ..Additionally, the two techniques are not mutually exclusive and can be combined. This trial was undertaken to determine whether the combination of flap repair and fibrin glue resulted in better outcomes than flap repair alone...
  69. ncbi Treatment of chronic fistula-in-ano using commercial fibrin glue
    Omer Elfaroug Y Tinay
    Division of General Surgery, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia
    Saudi Med J 24:1116-7. 2003
    ..To ascertain the effectiveness of commercially available fibrin glue in closing fistulae in ano...
  70. ncbi Preoperative MR imaging of anal fistulas: Does it really help the surgeon?
    R G Beets-Tan
    Department of Radiology, University Hospital of Maastricht, P Debyelaan 25, 6229 HX Maastricht, The Netherlands
    Radiology 218:75-84. 2001
    ..To evaluate the accuracy of magnetic resonance (MR) imaging with a quadrature phased-array coil for the detection of anal fistulas and to evaluate the additional clinical value of preoperative MR imaging, as compared with surgery alone...
  71. ncbi Efficacy of anal fistula plug in closure of Crohn's anorectal fistulas
    Lynn O'Connor
    Georgia Colon and Rectal Surgical Clinic, 5555 Peachtree Dunwoody Road, Atlanta, GA 30342, USA
    Dis Colon Rectum 49:1569-73. 2006
    ..The efficacy of Surgisis anal fistula plug in closure of Crohn's anorectal fistula was studied...
  72. ncbi Efficacy of fibrin sealant in the management of complex anal fistula: a prospective trial
    Gordon N Buchanan
    Department of Surgery, St Mark s Hospital, Harrow, United Kingdom
    Dis Colon Rectum 46:1167-74. 2003
    ..A prospective trial was conducted to establish long-term healing of complex idiopathic anorectal fistula, without extension, after fibrin glue treatment, with clinical assessment and magnetic resonance imaging to determine tract healing...
  73. ncbi Prostatourethral-rectal fistula after prostate brachytherapy
    D Theodorescu
    Department of Urology, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Cancer 89:2085-91. 2000
    ..Prostatourethral-rectal fistula (PRF) is a serious complication of this approach, and its incidence, clinical presentation, and risk factors ..
  74. ncbi Staged mucosal advancement flap for the treatment of complex anal fistulas: pretreatment with noncutting Setons and in case of recurrent multiple abscesses a diverting stoma
    S J van der Hagen
    Department of Surgery, Academic Hospital of Maastrucket, Maastricht, The Netherlands
    Colorectal Dis 7:513-8. 2005
    ..To assess the efficacy of a staged strategy for the treatment of complex perianal fistula...
  75. ncbi Imaging of fistula in ano
    Steve Halligan
    Department of Specialist Radiology, University College Hospital, Level 2, Podium, 235 Euston Road, London NW1 2BU, England
    Radiology 239:18-33. 2006
    ..Most important, the authors describe how the radiologist is well placed to answer the surgical riddles that must be solved for treatment to be effective...
  76. pmc Fibrin glue and transanal rectal advancement flap for high transsphincteric perianal fistulas; is there any advantage?
    Paul J van Koperen
    Department of Surgery, Academic Medical Center, University of Amsterdam, P O Box 22660, 1100 DD Amsterdam, The Netherlands
    Int J Colorectal Dis 23:697-701. 2008
    ....
  77. ncbi A randomized, controlled trial of fibrin glue vs. conventional treatment for anal fistula
    Ian Lindsey
    Department of Colorectal Surgery, John Radcliffe Hospital, Oxford, United Kingdom
    Dis Colon Rectum 45:1608-15. 2002
    ..We aimed to compare the outcomes of patients with low and high anal fistulas randomly assigned to either fibrin glue or conventional treatment...
  78. ncbi Efficacy of anal fistula plug in closure of cryptoglandular fistulas: long-term follow-up
    Bradley J Champagne
    Georgia Colon and Rectal Surgical Clinic, 5555 Peachtree Dunwoody Road, Atlanta, Georgia 30342, USA
    Dis Colon Rectum 49:1817-21. 2006
    ..The long-term efficacy of Surgisis anal fistula plug in closure of cryptoglandular anorectal fistulas was studied...
  79. ncbi Fecal incontinence severity index after fistulotomy: a predictor of quality of life
    Megan Cavanaugh
    Department of Surgery, University of Vermont College of Medicine, Burlington, USA
    Dis Colon Rectum 45:349-53. 2002
    ..The purpose of this study was to use the Fecal Incontinence Severity Index to assess fecal incontinence after fistulotomy and to correlate the Fecal Incontinence Severity Index score with quality-of-life measures...
  80. ncbi [Fistulas and fissures. Part I: perianal fistulas]
    W Heitland
    Klinikum Bogenhausen, Klinik für Visceral, Thorax und Gefasschirurgie, Städtisches Klinikum München GmbH, Englschalkinger Strasse 77, 81925 Munchen
    Chirurg 79:430-8. 2008
    ..Excision of the external fistula tract, closure of the internal opening, and a local advancement flap are now competing with fistulotomy, curettage, and immediate reconstruction...
  81. ncbi The treatment of anal fistula: ACPGBI position statement
    J G Williams
    McHale Centre, New Cross Hospital, Wolverhampton, UK
    Colorectal Dis 9:18-50. 2007
  82. ncbi Endorectal flap advancement repair is an effective treatment for selected patients with anorectal fistulas
    Matthew Dixon
    Division of Colon and Rectal Surgery, Harbor UCLA Medical Center, Torrance, California, USA
    Am Surg 70:925-7. 2004
    ..Anal advancement flaps demonstrate a reasonable success rate when utilized in this group of patients with challenging anorectal fistulas...
  83. ncbi Fibrin glue for fistula-in-ano: the evidence reviewed
    M T Swinscoe
    Academic Surgical Unit, Level 8, Clinical Sciences Building St James s University Hospital, Leeds LS9 7TF, United Kingdom
    Tech Coloproctol 9:89-94. 2005
    ..The quality of data to assess the efficacy of fibrin glue in the treatment of anal fistulae is poor and further clinical trials are needed. Fistula complexity is the main factor that adversely influences long-term healing rates...
  84. ncbi Long-term functional outcome and risk factors for recurrence after surgical treatment for low and high perianal fistulas of cryptoglandular origin
    Paul J van Koperen
    Department of Surgery, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Dis Colon Rectum 51:1475-81. 2008
    ..This study assessed long-term functional outcome and explored risk factors for fistula recurrence in patients surgically treated for cryptoglandular fistulas...
  85. ncbi Fistula-in-ano: advances in treatment
    Samer Deeba
    Department of Biosurgery and Surgical Technology, St Mary s Hospital, Norfolk Place, London W2 1NY, UK
    Am J Surg 196:95-9. 2008
    ..This review summarizes the history of fistula-in-ano management, the current techniques available, and describes new technologies...
  86. ncbi Bioprosthetic plugs for complex anal fistulas: an early experience
    C Neal Ellis
    Department of Surgery, University of South Alabama, Mobile, AL 36617, USA
    J Surg Educ 64:36-40. 2007
    ..The purpose of this study is to report the author's early experience with the bioprosthetic fistula plug and to compare the results of bioprosthetic plug closure of complex anal fistulas with those achieved with advancement flap repair...
  87. ncbi Impact of two different types of anal retractor on fecal continence after fistula repair: a prospective, randomized, clinical trial
    David D E Zimmerman
    Department of Surgery, Colorectal Research Group, Erasmus Medical Center, Rotterdam, The Netherlands
    Dis Colon Rectum 46:1674-9. 2003
    ..This study was designed to compare two different types of anal retractors (Parks vs. Scott) with regard to their impact on fecal continence after fistula repair...
  88. ncbi Obliteration of the fistulous tract with BioGlue adversely affects the outcome of transanal advancement flap repair
    S M Alexander
    Colorectal Research Group Department of Surgery, Erasmus Medical Center Rotterdam, H 896 s Gravendijkwal 230, Rotterdam, The Netherlands
    Tech Coloproctol 12:225-8. 2008
    ..The aim of this pilot study was to investigate whether concomitant instillation of BioGlue could improve the healing rate following TAFR for high transsphincteric fistulas...
  89. ncbi Fibrin glue for all anal fistulas
    S M Sentovich
    Department of Surgery, Boston University School of Medicine, Mass, USA
    J Gastrointest Surg 5:158-61. 2001
    ..Functional results have remained excellent with no patient reporting any change in continence after treatment. Fibrin glue is simple and effective treatment for all anal fistulas with excellent functional results...
  90. ncbi LIFT procedure: a simplified technique for fistula-in-ano
    A Rojanasakul
    Colorectal Division, Chulalongkorn University, Bangkok, Thailand
    Tech Coloproctol 13:237-40. 2009
    ..Attention to detail is the key for a favorable outcome...
  91. ncbi Randomized clinical trial of anal fistula plug versus endorectal advancement flap for the treatment of high cryptoglandular fistula in ano
    H Ortiz
    Department of Surgery, Hospital Virgen del Camino, Universidad Publica de Navarra, Pamplona, Spain
    Br J Surg 96:608-12. 2009
    ..The aim of this randomized study was to compare the results of anal fistula plug and endorectal advancement flap in the treatment of high fistula in ano of cryptoglandular origin...
  92. ncbi Ligation of the intersphincteric fistula tract: an effective new technique for complex fistulas
    Joshua I S Bleier
    University of Pennsylvania, Pennsylvania Hospital, Division of Colon and Rectal Surgery, Philadelphia, Pennsylvania 19106, USA
    Dis Colon Rectum 53:43-6. 2010
    ..This study describes our experience with a novel sphincter-sparing technique called the ligation of the intersphincteric fistula tract, which involves ligation and division of the fistula tract in the intersphincteric space...
  93. ncbi Fibrin glue in perianal fistulas--a pilot study
    P Aitola
    Department of Surgery, Tampere University Hospital and Medical School, University of Tampere, Finland
    Ann Chir Gynaecol 88:136-8. 1999
    ..There were no reports of the use of fibrin glue in the management of previously untreated anal fistulas...
  94. ncbi Implantation of rectal cancer cells in a fistula in ano: report of a case
    T Shinohara
    Department of Surgery, Kyouritsu General Hospital, Nagoya, Japan
    Surg Today 31:1094-6. 2001
    ..Because there was no continuity to the rectal carcinoma or the anal glands, we diagnosed implantation of rectal cancer cells in a fistula in ano...
  95. ncbi Anal fistulotomy between Skylla and Charybdis
    M Westerterp
    Lucas Andreas Ziekenhuis Amsterdam, Amsterdam, The Netherlands
    Colorectal Dis 5:549-51. 2003
    ..This study was undertaken to assess the results of anal fistulotomy on faecal continence, recurrence and satisfaction...
  96. ncbi Anal fistula plug for closure of difficult anorectal fistula: a prospective study
    Paul J van Koperen
    Department of Surgery, Academic Medical Center, PO Box 22660, Amsterdam, 1100 DD, The Netherlands
    Dis Colon Rectum 50:2168-72. 2007
    ..To assess the results of the anal fistula plug in patients with complex high perianal fistulas, a prospective, two-center, clinical study was undertaken...
  97. ncbi [A case of anal fistula cancer probably developing from intraluminal dissemination of rectal cancer]
    Yoshito Tomimaru
    Dept of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases
    Gan To Kagaku Ryoho 32:1776-8. 2005
    ..We may suggest from these results that cancer cells from the rectal cancer had been implanted and developed the metastatic tumor in the anal canal...
  98. ncbi Radio frequency "sutureless" fistulotomy- a new way of treating fistula in anus
    Pravin J Gupta
    Gupta Nursing Home, D 9, Laxminagar, Nagpur 440022, India
    World J Gastroenterol 9:1082-5. 2003
    ..To explore the effect of the classical lay open technique or fistulotomy with the radio frequency surgical device in the treatment of fistula in anus...
  99. ncbi Long-term outcome following loose-seton technique for external sphincter preservation in complex anal fistula
    G N Buchanan
    Department of Surgery, St Mark s Hospital, Northwick Park, Harrow, UK
    Br J Surg 91:476-80. 2004
    ..This study determined the long-term outcome after use of the loose-seton technique (LST) to eradicate complex fistula in ano...
  100. ncbi Perianal abscess: a pilot study comparing packing with nonpacking of the abscess cavity
    Darren M Tonkin
    Gastrointestinal Surgery, Flinders Medical Centre, Adelaide, Australia
    Dis Colon Rectum 47:1510-4. 2004
    ..Perianal sepsis is traditionally treated by incision and drainage, with packing of the residual cavity until healing. This study was designed to show that perianal abscess may be safely treated by incision and drainage alone...
  101. ncbi Clinical examination, endosonography, and MR imaging in preoperative assessment of fistula in ano: comparison with outcome-based reference standard
    Gordon N Buchanan
    Departments of Surgery and Intestinal Imaging, St Mark s Hospital, Level 4V, Watford Road, Northwick Park, Harrow, London HA1 3UJ, England
    Radiology 233:674-81. 2004
    ..To prospectively evaluate the relative accuracy of digital examination, anal endosonography, and magnetic resonance (MR) imaging for preoperative assessment of fistula in ano by comparison to an outcome-derived reference standard...

Research Grants1

  1. ROLE OF HYALURONAN IN INFLAMMATORY BOWEL DISEASE
    Scott Strong; Fiscal Year: 2005
    ..abstract_text> ..