Genomes and Genes
Summary: Formation of a clot composed of platelets and fibrin within the lumen of an intracranial artery or vein, which may result in CEREBRAL INFARCTION. Arterial thrombosis is associated with INTRACRANIAL ARTERIOSCLEROSIS, but may also result from hypercoagulability states (see THROMBOPHILIA). Cerebral vein thrombosis is frequently complicated by INTRACRANIAL HEMORRHAGES.
Articles from Journal RESEARCH
Articles from Journal RESEARCH1
Publications218 found, 100 shown here
- Disturbance of perineuronal nets in the perilesional area after photothrombosis is not associated with neuronal deathMagdalena Karetko-Sysa
Department of Molecular and Cellular Neurobiology, The Nencki Institute of Experimental Biology, Warsaw, Poland
Exp Neurol 231:113-26. 2011..Our results suggest that the PNN reduction was not a result of cellular death and could be considered an attempt to create conditions favorable for synaptic remodeling...
- Photochemically induced cerebral ischemia in a mouse modelJung Kil Lee
Department of Neurosurgery, Chonnam National University Hospital, Gwangju 501 757, South Korea
Surg Neurol 67:620-5; discussion 625. 2007..MCAO has been widely used to produce ischemic brain lesions. The lesions induced by MCAO tend to be variable in size because of the variance in the collateral blood supply found in the mouse brain...
- Cerebral venous thrombosis: diagnosis and managementM G Bousser
Hôpital Lariboisière Service de Neurologie, Paris, France
J Neurol 247:252-8. 2000..Diagnosis and treatment of CVT should be considered as an emergency because of the considerable potential for full recovery in this condition...
- Visualization of stroke with clinical MR imagers in rats: a feasibility studyFeng Chen
Department of Radiology, University Hospitals, K U Leuven, Herestraat 49, B 3000 Leuven, Belgium
Radiology 233:905-11. 2004..05). There was no difference in lesion size at perfusion-weighted MR imaging between superacute and subacute phases (P > .05). Performance of certain stroke-related research in rats is feasible with clinical MR imagers...
- Dynamic changes of magnetic resonance imaging abnormalities in relation to inflammation and glial responses after photothrombotic cerebral infarction in the rat brainM Schroeter
Department of Neurology, Heinrich Heine University, Duesseldorf, Germany
Acta Neuropathol 101:114-22. 2001..Heterogeneous ADC together with T2 elevation reflected a late infarct stage (14 days) when pseudocystic degeneration and scar formation had occurred...
- Headache as the only neurological sign of cerebral venous thrombosis: a series of 17 casesR Cumurciuc
Department of Neurology, Lariboisiere Hospital, 2 rue Ambroise Pare, 75010 Paris, France
J Neurol Neurosurg Psychiatry 76:1084-7. 2005..Headache is the most frequent symptom in cerebral venous thrombosis (CVT), and usually the first. However, it has rarely been reported as the only symptom of CVT...
- Non-invasive induction of focal cerebral ischemia in mice by photothrombosis of cortical microvessels: characterization of inflammatory responsesMichael Schroeter
Department of Neurology, Heinrich Heine Universitaet, Moorenstrasse 5, D 40225 Duesseldorf, Germany
J Neurosci Methods 117:43-9. 2002..It may provide a useful model to study functional aspects of lesion-associated and remote molecular responses in transgenic mice...
- Hardware and methodology for targeting single brain arterioles for photothrombotic stroke on an upright microscopeAlbrecht Sigler
Kinsmen Laboratory of Neurological Research, Department of Psychiatry, 2255 Wesbrook Mall, University of British Columbia, Vancouver, BC, Canada
J Neurosci Methods 170:35-44. 2008..It is conceivable that this modification and laser system can also be used for other scenarios where targeted photoactivation or photobleaching would be required...
- Should decompressive surgery be performed in malignant cerebral venous thrombosis?: a series of 12 patientsMarie Théaudin
AP HP, Hopital Bicetre, Service de Neurologie, Le Kremlin Bicetre, France
Stroke 41:727-31. 2010..In malignant cerebral venous thrombosis (CVT) patients, emergency decompressive surgery has been suggested as a life-saving procedure. We report 12 patients with malignant CVT, among whom 8 underwent operation...
- Natural history of cerebral vein thrombosis: a systematic reviewFrancesco Dentali
Department of Medicine, McMaster University, Hamilton, ON, Canada
Blood 108:1129-34. 2006..8% (range, 0%-11.7%) had objectively confirmed recurrence. We conclude that patients with CVT have a low risk of death and that most patients have a good long-term prognosis...
- Causes and predictors of death in cerebral venous thrombosisPatrícia Canhão
Department of Neurosciences and Mental Health, Hospital Santa Maria, 1649 035 Lisbon, Portugal
Stroke 36:1720-5. 2005..We aimed to analyze the causes and predictors of death during the acute phase of CVT in the International Study on Cerebral Vein and Dural Sinus Thrombosis (ISCVT) to identify preventable or treatable causes...
- Cerebral venous thrombosis: an updateMarie Germaine Bousser
AP HP Hôpital Lariboisière Service de Neurologie, Paris, France
Lancet Neurol 6:162-70. 2007..Heparin is the first-line treatment, but in a few cases more aggressive treatments, such as local intravenous thrombolysis, mechanical thrombectomy, and decompressive hemicraniectomy, may be required...
- Cerebral venous thrombosis in childrenK S Carvalho
Division of Pediatric Neurology, Indiana University School of Medicine, James Whitcomb Riley Hospital for Children, Indianapolis, USA
J Child Neurol 16:574-80. 2001..Two had other deficits. Neonatal cerebral venous thrombosis is probably more common than previously thought, and outcomes are worse in this group. All children with cerebral venous thrombosis should be tested for coagulation disorders...
- Cerebral venous and sinus thrombosis: incidence and causesJan Stam
Department of Neurology, University of Amsterdam, Academic Medical Centre, Amsterdam, The Netherlands
Adv Neurol 92:225-32. 2003
- Diagnostic pitfalls in paediatric ischaemic strokeKees P J Braun
Department of Child Neurology, University Medical Centre Utrecht, The Netherlands
Dev Med Child Neurol 48:985-90. 2006..We recommend that children with stroke be evaluated in a centre with expertize, using standardized diagnostic protocols and careful follow-up...
- Do normal D-dimer levels reliably exclude cerebral sinus thrombosis?Christoph M Kosinski
Department of Neurology, Universitatsklinikum Aachen, Pauwelsstrasse 30, D 52074 Aachen, Germany
Stroke 35:2820-5. 2004..Because measurement of D-dimers has been demonstrated to be helpful in excluding thromboembolic disease, our aim was to investigate whether D-dimers would be also sensitive enough to exclude CST...
- Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatmentGuido Stoll
Department of Neurology, University of Wurzburg, Wurzburg, Germany
Blood 112:3555-62. 2008..This review discusses recent advances related to antithrombotic strategies in experimental stroke research...
- Utility of D-dimer in the diagnosis of cerebral venous sinus thrombosisB Cucchiara
J Thromb Haemost 3:387-9. 2005
- In vivo detection of developing vessel occlusion in photothrombotic ischemic brain lesions in the rat by iron particle enhanced MRIChristoph Kleinschnitz
Department of Neurology, Julius Maximilians Universitat Wurzburg, Wurzburg, Germany
J Cereb Blood Flow Metab 25:1548-55. 2005..This new imaging technique may aid to evaluate antithrombotic treatment strategies in the future...
- Subacute hemorrhage and resolution of edema in Rose Bengal stroke model in rats coincides with improved sensorimotor functionsJukka Jolkkonen
Department of Neurology, University of Kuopio, P O Box 1627, 70211 Kuopio, Finland
Neurosci Lett 428:99-102. 2007..The results suggest that bleeding around cortical infarct is part of the wound healing process and may not impair functional outcome...
- Cerebral venous thrombosis 3-year clinical outcome in 55 consecutive patientsG Breteau
Dept of Neurology, Lens Hospital, Lens, France
J Neurol 250:29-35. 2003..However, 3/4 of survivors have residual symptoms. Therefore, despite a low mortality rate, CVT remains a serious disorder...
- Cerebral venous thrombosis in children: a multifactorial originChristine Heller
Department of Pediatrics Pediatric Hematology and Oncology, University of Frankfurt am Main, Germany
Circulation 108:1362-7. 2003....
- Carboxypeptidase U (TAFIa) decreases the efficacy of thrombolytic therapy in ischemic stroke patientsRaf Brouns
Department of Neurology and Memory Clinic, ZNA Middelheim Hospital, Antwerp, Belgium
Clin Neurol Neurosurg 111:165-70. 2009..In vitro and in vivo data suggest that activation of procarboxypeptidase U (proCPU) inhibits fibrinolysis...
- Apoptotic cell death progression after photothrombotic focal cerebral ischaemia: effects of the lipophilic iron chelator 2,2'-dipyridylMichael van Hoecke
Laboratoire de Pharmacodynamie et Physiologie Pharmaceutique L3P, Faculte de Pharmacie, BP 87900, 21079 Dijon Cedex, France
Eur J Neurosci 22:1045-56. 2005..Furthermore, a large decrease of apoptotic bodies was associated with a significant drop of caspase and PARP-1 cleavages, suggesting that the protective effect of DP closely correlates with limitation of apoptosis expansion...
- A negative D-dimer assay does not rule out cerebral venous thrombosis: a series of seventy-three patientsIsabelle Crassard
Neurology Department, Lariboisiere Hospital, 2 rue Ambroise Pare, 75010 Paris, France
Stroke 36:1716-9. 2005..Previous reports have emphasized the potential clinical utility of D-dimer assay in CVT diagnosis...
- Cerebral thrombosis in childhood nephrosisArun Gangakhedkar
Kidz First Community Health, Otahuhu, New Zealand
J Paediatr Child Health 41:221-4. 2005..We describe this case and review available literature to highlight the importance of suspecting and recognizing this potentially life threatening complication and initiating early treatment...
- Diffusion-weighted mr in cerebral venous thrombosisK O Lovblad
Department of Neuroradiology, Inselspital, University of Bern, Switzerland
Cerebrovasc Dis 11:169-76. 2001..It can also demonstrate early ischemic changes, and can differentiate conventional T2-weighted MR areas of cytotoxic from vasogenic edema...
- Clinical picture of patients with cerebral venous thrombosis and patterns of dural sinus involvementMauro Bergui
Department of Neuroradiology, University of Turin, Ospedale S Giovanni Battista, Turin, Italy
Cerebrovasc Dis 16:211-6. 2003..Cerebral venous thrombosis may cause focal brain lesions or an isolated intracranial hypertension without focal signs. We investigated whether these different clinical pictures correspond to different patterns of dural sinus thrombosis...
- Cerebral venous thrombosis, intraventricular haemorrhage and white matter lesions in a preterm newborn with factor V (Leiden) mutationL A Ramenghi
Paediatric Department, University of Leeds, General Infirmary at Leeds, UK
Neuropediatrics 33:97-9. 2002..The baby was later found to be heterozygous for factor V Leiden...
- Long-term prognosis of cerebral vein and dural sinus thrombosis. results of the VENOPORT studyJ M Ferro
Department of Neurology, Hospital de Santa Maria, Lisboa, Portugal
Cerebrovasc Dis 13:272-8. 2002..The long-term functional prognosis of patients with CVDST was fairly good with complete recovery in the majority of cases. However, these patients had a moderate risk of further thrombotic events and seizures...
- Isolated lateral sinus thrombosis: a series of 62 patientsMariem Damak
Neurology Department, Lariboisiere Hospital, Paris, France
Stroke 40:476-81. 2009..Little attention has been recently paid to this variety of thrombosis. We therefore reviewed all cases of isolated lateral sinus thrombosis prospectively collected in our center (1997 to 2006)...
- Cerebral vein and dural sinus thrombosis in elderly patientsJose M Ferro
Department of Neurosciences and Mental Health, Hospital Santa Maria, 1649 035 Lisbon, Portugal
Stroke 36:1927-32. 2005..The clinical features and prognosis of cerebral vein and dural sinus thrombosis (CVT) in elderly patients have not been previously described...
- Early seizures in cerebral vein and dural sinus thrombosis: risk factors and role of antiepilepticsJose M Ferro
Department of Neurosciences and Mental Health, Hospital Santa Maria, Lisboa, Portugal
Stroke 39:1152-8. 2008..The risk of seizure early after the diagnosis of cerebral vein and dural sinus thrombosis (CVT) is not known, and the use of prophylactic antiepileptic (AED) medication in the acute phase of CVT is controversial...
- Obstetric cerebral venous thrombosisBhojo A Khealani
Neurology Section, Department of Medicine, The Aga Khan University, Karachi
J Pak Med Assoc 56:490-3. 2006..During puerperium additional risk factors include infection and instrumental delivery or Caesarean section. The management follows general rules as for the venous thrombosis unrelated to pregnancy, however the prognosis is different...
- Angiographic analysis of intravascular thrombus volume in patients with acute ischemic strokeAdnan I Qureshi
Imaging Core Laboratory, Zeenat Qureshi Stroke Research Center, Department of Neurology and Neurosciences, University of Medicine and Dentistry of New Jersey, Newark, USA
J Endovasc Ther 14:475-82. 2007..To investigate the role that intravascular thrombus volume plays in mechanical thrombectomy and dose-titrated algorithms using pharmaceutical thrombolytic therapies...
- Delayed cerebral venous thrombosis in a patient with spontaneous intracranial hypotensionM Y Lan
Departments of Neurology, Chang Gung Memorial Hospital Kaohsiung Medical Centre, Chang Gung University College of Medicine, Kaohsiung County 833, Taiwan
Cephalalgia 27:1176-8. 2007
- Neurological complications of paroxysmal nocturnal hemoglobinuriaN Jewel Samadder
Can J Neurol Sci 34:368-71. 2007
- Cerebral cortical and deep venous thrombosis without sinus thrombosis: clinical MRI correlatesA Sagduyu
Stroke Unit, Department of Neurology, Ege University School of Medicine, Izmir, Turkey
Acta Neurol Scand 114:254-60. 2006..Our aim is to determine the relationship between magnetic resonance imaging (MRI) findings and clinical findings in patients with CDVT...
- Neuroimaging of cerebral venous thrombosisMohammad Wasay
Department of Neurology, The Aga Khan University, Karachi, Pakistan
J Neuroimaging 15:118-28. 2005..Contrast angiography should be strongly considered if isolated cortical vein thrombosis is suspected...
- Ictal monoparesis associated with lesions in the primary somatosensory areaR Matsumoto
Department of Neurology, Kyoto University Graduate School of Medicine, Kyoto, Japan
Neurology 65:1476-8. 2005..In the presence of an SI lesion, the epileptic activity at the sensorimotor area could lead to selective or predominant activation of the inhibitory motor system...
- [Isolated cortical vein thrombosis. Clinical and neuroradiological aspects]W Muller-Forell
Institut für Neuroradiologie, Klinikum der Johannes Gutenberg Universitat, 55101Mainz
Radiologe 47:255-61. 2007..We report on five patients with this diagnosis, who all presented with focal sensomotoric seizures. Imaging with CT and MRI was the leading method. All patients were treated with oral anticoagulation and showed full recovery...
- Interventional neuroradiology in the treatment of cerebral venous thrombosisValeria Caso
Stroke Unit and Division of Cardiovascular Medicine, Department of Internal Medicine, University of Perugia, Santa Maria della Misericordia Hospital, Via Dottori, Sant Andrea delle Fratte, Perugia, Italy
Front Neurol Neurosci 23:144-60. 2008..There is no reason to recommend interventional radiology in these patients who are likely to have a good outcome unless proven superior in a trial...
- Resolution of bilateral thalamic lesions due to deep cerebral venous thrombosisDaniel C Bezerra
Department of Neurology, Lausanne, Switzerland
Arch Neurol 62:1638-9. 2005
- [Current controversies in the diagnosis and management of cerebral venous and dural sinus thrombosis]S Schwarz
Neurologische Universitatsklinik, Klinikum Mannheim, Mannheim
Nervenarzt 74:639-53. 2003..Both methods have a high sensitivity for cerebral venous thrombosis. Local fibrinolytic therapy or other aggressive recanalizing methods can not be generally recommended...
- [Isolated cortical vein thrombosis: report of two cases]Héctor Miranda V
Intermedio Neurológico, Departamento de Neurologia, Hospital Clinico, Pontificia Universidad Catolica de Chile, Santiago, Chile
Rev Med Chil 135:1313-7. 2007..Neuroimages show ischemic abnormalities that do not follow an arterial vascular territory, often with an early hemorrhagic component. There is a good clinical response to heparin...
- Cerebral venous thrombosis: analysis of a multicenter cohort from the United StatesMohammad Wasay
Aga Khan University, Karachi, Pakistan
J Stroke Cerebrovasc Dis 17:49-54. 2008..The data regarding diagnosis, prognosis, management, and outcome of patients with cerebral venous thrombosis are limited from the United States...
- Intracranial bilateral vertebral artery dissection during anticoagulation after cerebral venous and sinus thrombosis (CSVT)B Turowski
Department of Neuroradiology, Institute of Diagnostic Radiology, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
Acta Neurochir (Wien) 149:793-7; discussion 797. 2007..Endovascular occlusion of the pathological segment of the right vertebral artery including the dissecting aneurysm and conservative management of the other side resulted in complete recovery without neurological complications...
- Haematologic disorders and cerebral venous thrombosisNaveed Akhtar
Hamad Medical Corporation, Doha, Qatar
J Pak Med Assoc 56:498-501. 2006..If a hereditary hypercoagulable state is found, it also may be appropriate to recommend screening of other family members...
- Unusual causes of cerebral venous thrombosisIsmail A Khatri
Department of Neurology, Dow University of Health Sciences and Civil Hospital, Karachi
J Pak Med Assoc 56:501-6. 2006..In this review, we have focused on relatively rare and unusual causes of cerebral venous thrombosis. Many of the conditions described have very few reported cases and the causal relationship is not well established...
- Pathophysiology of cerebral venous thrombosis--an overviewAhmed Itrat
Department of Neurology, The Aga Khan University, Karachi
J Pak Med Assoc 56:506-8. 2006..Pathophysiology of CVST is diverse and makes it easier to understand the diversity of clinical presentations...
- Mechanism of neuronal injury in cerebral venous thrombosisUzma Usman
Department of Neurology, The Aga Khan University, Karachi
J Pak Med Assoc 56:509-12. 2006....
- Cerebral venous thrombosis--clinical presentationsMan Mohan Mehndiratta
Department of Neurology, G B Pant Hospital, New Delhi 110002, India
J Pak Med Assoc 56:513-6. 2006..5 years. Of the 4 females two were postpartum; one was on oral contraceptive and in one Antiphospholipid antibodies (APLA) were positive. Amongst two males one had hyperhomocysteinemia and one had hyperlipidemia...
- Cerebral venous system anatomyMuhammad Azeem Uddin
Department of Radiology, Aga Khan University Hospital, Karachi
J Pak Med Assoc 56:516-9. 2006..With the exception of wide variations of basal vein, the deep system is rather constant compared to the superficial venous system. Hence their thrombosis is easy to recognize...
- Computed tomographic imaging of cerebral venous thrombosisMohammad Kamran Kamal
Department of Radiology, The Aga Khan University Hospital, Karachi
J Pak Med Assoc 56:519-22. 2006..A brief discussion of CT venography, which has come around as a promising tool for diagnosing CVT as a result of newer innovations in CT technology, is also included here...
- MRI and MRV in cerebral venous thrombosisZafar Sajjad
Department of Radiology, Aga Khan University Hospital, Karachi
J Pak Med Assoc 56:523-6. 2006..Appearances of these lesions too are dependent on their age. Diffuse changes of raised intracranial pressure with gyral effacement may also be present...
- Cerebral angiography and venography for evaluation of cerebral venous thrombosisNazli Janjua
University of Medicine and Dentistry of New Jersey, Newark, NJ 07113, USA
J Pak Med Assoc 56:527-30. 2006..Knowledge of the normal drainage patterns of the cerebral venous system is essential in interpreting angiographic information obtained in the evaluation of patients with suspected cerebral venous thrombosis...
- Heparin in the treatment of cerebral venous thrombosisSaad Shafqat
Department of Medicine Neurology, Aga Khan University Medical College, Karachi
J Pak Med Assoc 56:541-3. 2006..Newer antithrombotic agents such as ximelagatran may offer advantages over heparin and need to be investigated in the treatment of CVT...
- Complications associated with cerebral venous thrombosisFazeel Mukhtar Siddiqui
Department of Medicine, The Aga Khan University Hospital, Karachi
J Pak Med Assoc 56:547-51. 2006..g. pulmonary embolism. The chronic complications are rare but are potentially treatable, e.g. dural AVFistula nidus obliteration with intervention...
- Developmental venous anomaly with an arteriovenous shunt and a thrombotic complication. Case reportS Agazzi
Department of Neurosurgery, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
J Neurosurg 94:533-7. 2001..Although no treatment can be offered, the presence of an AV shunt in a DVA warrants close follow-up observation because such lesions may represent a particular subtype of AVM and, therefore, may exhibit an aggressive clinical behavior...
- Role of heparin and low-molecular-weight heparins in the management of acute ischemic strokeVasantha Padma
All India Institute of Medical Science, Dehli, India
Expert Rev Cardiovasc Ther 4:405-15. 2006..High-quality, randomized trials that adequately study heparin use in patients using modern technology for vascular lesions and stroke subtypes are lacking, and need to be performed...
- [Cerebral venous thrombosis--diagnosis and treatment]Hans Jørgen Johnsen
Avdeling for nevrologi og klinisk nevrofysiologi, St Olavs Hospital, Olav Kyrres gate 17, 7006 Trondheim
Tidsskr Nor Laegeforen 127:1069-73. 2007..This review article concerns the aetiology, pathology, diagnostic work-up and treatment of the condition...
- Anemia as a risk factor for cerebral venous thrombosis? An old hypothesis revisited. Results of a prospective studyErwin Stolz
Dept of Neurology, Justus Liebig University, Am Steg 14, 35385 Giessen, Germany
J Neurol 254:729-34. 2007..Several case reports have linked iron deficiency anemia with the occurrence of cerebral venous thrombosis (CVT) or stroke, yet, it is unclear whether this is a chance association...
- Cerebral veins and sinusesErwin Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
Front Neurol Neurosci 21:182-93. 2006..It was not until the mid-1990s that venous transcranial ultrasound in adults was systematically developed. In the following the examination technique and clinical applications of this technique are summarized...
- Spontaneous thrombosis of cerebral aneurysms presenting with ischemic strokeJose E Cohen
Department of Neurosurgery, Hadassah Hebrew University Hospital, Jerusalem, Israel Department of Radiology, Hadassah Hebrew University Hospital, Jerusalem, Israel
J Neurol Sci 254:95-8. 2007..We present documented cases of this unusual entity and review the literature...
- Deep cerebral vein thrombosis associated with iron deficiency anaemia in adultsKemal Balci
Department of Neurology, Faculty of Medicine, University of Trakya, Edirne 22030, Turkey
J Clin Neurosci 14:181-4. 2007..Both of our patients had severe hypochromic microcytic anaemia due to iron deficiency, and both had a good prognosis after 2 months...
- Cerebral venous thrombosis: recent advances and need for an Asian registryMohammad Wasay
J Pak Med Assoc 56:483-4. 2006
- Incidence and epidemiology of cerebral venous thrombosisFazeel Mukhtar Siddiqui
The Aga Khan University Hospital, Karachi
J Pak Med Assoc 56:485-7. 2006..The newer epidemiologic data derived from a Caucasian database; suggest a better overall prognosis, younger age at distribution than arterial stroke...
- Paediatric cerebral venous thrombosisAlper I Dai
Department of Pediatrics, Shcool of Medicine, Gaziantep University, Gaziantep, Turkey
J Pak Med Assoc 56:531-5. 2006..Anticoagulant treatment with heparin is probably safe and beneficial for children with sinus thrombosis, even those with intracranial haemorrhages...
- [Cerebral venous thrombosis associated to subacute De Quervain's thyroiditis in a carrier for the G20210A mutation of the prothrombin gene]A B Madroñero-Vuelta
Servicio de Medicina Interna, Hospital Universitario Arnau de Vilanova, Lleida, Spain
Rev Neurol 39:533-5. 2004..We present a case of CVT associated to a subacute De Quervain's thyroiditis in a young female who was an heterozygous carrier for the G20210A mutation of the prothrombin gene...
- [Cerebral venous thrombosis]J M Ferro
Service de Neurologie, Hospital Santa Maria, 1649 035 Lisboa, Portugal
J Neuroradiol 29:231-9. 2002..There are few randomized trials upon which to base treatment recommendations...
- Genetics of cerebral venous thrombosisArsalan Ahmad
Section of Neurology, Shifa International Hospitals and College of Medicine, Islamabad
J Pak Med Assoc 56:488-90. 2006..Maternal and foetal testing is suggested when CVT occurs in neonates...
- Intracranial venous hemodynamics is a factor related to a favorable outcome in cerebral venous thrombosisErwin Stolz
Department of Neurology, Justus Liebig University, Giessen, Germany
Stroke 33:1645-50. 2002..However, it is conceivable that the presence or absence and the efficiency of venous collaterals, as well as recanalization, may have an impact on brain tissue damage and hence on the prognosis of acute CVT...
- Cerebral venous thrombosisIsabelle Crassard
Department of Neurology, Hopital Lariboisiere, Paris, France
J Neuroophthalmol 24:156-63. 2004..Cerebrospinal fluid diversion or optic nerve fenestration is used for vision-threatening papilledema when intracranial pressure control is difficult...
- Cerebral venous thrombosis and venous malformations in childrenKaren S Carvalho
James Whitcomb Riley Hospital for Children, Section of Pediatric Neurology, Indiana University Medical Center, 702 Barnhill Drive, Room 1757, Indianapolis, IN 46202 5200, USA
Neurol Clin 20:1061-77. 2002..Awareness of these potential causes of stroke in the pediatric population, early diagnosis, and appropriate therapeutic strategies are paramount to reduce mortality and improve neurologic outcome...
- [Unilateral internal cerebral vein thrombosis in MRI]O Wittkugel
Neuroradiologische Abteilung, Radiologische Klinik, Universitatsklinikum Hamburg Eppendorf
Rofo 176:259-61. 2004
- Recanalisation of cerebral venous thrombosisR W Baumgartner
Department of Neurology, University Hospital of Zurich, Frauenklinikstrasse 26, CH 8091 Zurich, Switzerland
J Neurol Neurosurg Psychiatry 74:459-61. 2003..To investigate recanalisation in the first 12 months after cerebral venous thrombosis...
- [Therapeutic interventional neuroradiology in acute stroke]G Schroth
Abteilung für Neuroradiologie DRNN Departement Radiologie, Neuroradiologie, Nuklearmedizin, Universität Bern im Inselspital, CH 3010 Bern
Ther Umsch 60:569-83. 2003..g., thrombolysis by ultrasound (sonothrombolysis), by angiojet aspiration, and laser evaporation of the thromboembolic occlusion of intra- and extracranial blood vessels...
- Risk of recurrence of cerebral venous and sinus thrombosis during subsequent pregnancy and puerperiumS Mehraein
Department of Neurology, Charite Medical School, Humboldt Universitat, Berlin, Germany
J Neurol Neurosurg Psychiatry 74:814-6. 2003..To assess the risk of recurrence of cerebral venous and sinus thrombosis (CVST) during subsequent pregnancy and puerperium in women with previous cerebral venous occlusive disease...
- [Cerebral venous thrombosis. Clinical presentation of three cases]Mogens Kegel
Røntgendiagnostisk Afdeling, Sønderborg Sygehus, Neurologisk afdeling N
Ugeskr Laeger 165:1882-3. 2003..The patients were treated with heparin. One developed blindness due to optic nerve atrophy. One had discreet cognitive deficits, and the last patient had no neurological sequelae after she was discharged from the hospital...
- Cerebral arterial thrombosis in paroxysmal nocturnal hemoglobinuriaSebastian von Stuckrad-Barre
J Neurol 250:756-7. 2003
- Sinus thrombosis after a jump from a small rock and a sneezing attack: minor endothelial trauma as a precipitating factor for cerebral venous thrombosis?Carina Rottger
Department of Neurology, University of Giessen, Germany
Headache 44:812-5. 2004..In about 20% of CVT cases the cause remains unclear. As minor head trauma may not have been recognized during history taking, this may represent a so far under-recognized precipitating factor for CVT...
- Small aneurysms as a cause of thromboembolic strokeM Smrcka
Neurosurgical Department, University Hospital Brno, Czech Republic
Bratisl Lek Listy 103:250-3. 2002..Only a few examples are available in the literature of patients with smaller aneurysms who develop embolic infarction distal to the lesion. We have experience with two such patients with an apparent common pathophysiology...
- Intra-arterial thrombolysis of complete deep cerebral venous thrombosisM Liebetrau
Department of Neurology, Klinikum Grosshadern, Munich, Germany
Neurology 63:2444-5. 2004
- [Progression of cerebral venous thromboses. A retrospective study]G Rodier
Service de Neurologie, Hôpital E Muller Mulhouse
Presse Med 32:728-33. 2003..Long term outcome of patients with cerebral venous thrombosis (CVT) has rarely been described. We present the results of a follow-up study...
- [A study on the diagnosis and etiology of cerebral venous thrombosis]Guihong Wang
Department of Neurology, Tiantan Hospital, The Capital University of Medical Science, Beijing 100050, China
Zhonghua Nei Ke Za Zhi 41:595-8. 2002..To determine the clinical characteristic and common etiologies of cerebral venous thrombosis (CVT) in China...
- Cerebral venous thrombosis: correlation between recanalization and clinical outcome--a long-term follow-up of 40 patientsM Strupp
J Neurol 249:1123-4. 2002
- A novel method of drug delivery for fibrinolysis with Ho:YAG laser-induced liquid jetT Hirano
Department of Neurosurgery, Tohoku University Graduate School of Medicine, Seiryou machi, Japan
Lasers Med Sci 17:165-72. 2002..After resolving some problems, this system will be applied to an endovascular therapy for cerebral embolisms in the near future...
- Extension of intracranial thrombosis after unilateral dissection of the internal jugular veinEike Gunther Wüstenberg
Department of Otorhinolaryngology, University Hospital Dresden, 01307 Dresden, Germany
Arch Otolaryngol Head Neck Surg 131:430-3. 2005..The aim of this study was to determine the extension of possible intracranial thrombosis after wound healing.
- Enhancement of fibrinolytics with a laser-induced liquid jetT Hirano
Department of Neurosurgery, Tohoku University Graduate School of Medicine, 1 1, Seiryou machi, Aoba ku, Sendai 980 8574, Japan
Lasers Surg Med 29:360-8. 2001..There is thus need of a new method of removing a cerebral thrombus more rapidly using smaller amounts of fibrinolytics...
- Snare retrieval of intracranial thrombus in patients with acute strokeCharles W Kerber
Department of Radiology, University of California San Diego Medical Center, 200 West Arbor Drive, San Diego, California 92103, USA
J Vasc Interv Radiol 13:1269-74. 2002..This experience also suggests that immediate removal of a mature clot could reduce the total time of brain ischemia more quickly than administration of thrombolytic drugs...
- Intra-arterial tissue plasminogen activator for thrombosis complicating cerebral angiography in a 17-year-old girlMeredith R Golomb
The Hospital for Sick Children, Toronto, Ontario
J Child Neurol 18:420-3. 2003Few reports describe the use of intraarterial recombinant tissue plasminogen activator to treat intracranial thrombosis in children...
- Thrombosed fetal dural sinus malformation diagnosed with magnetic resonance imagingM Vittoria Spampinato
Department of Radiology, Medical University of South Carolina, Charleston, South Carolina 29425, USA
Obstet Gynecol 111:569-72. 2008..Dural sinus malformations are rare congenital forms of dural arteriovenous shunt. Our goal is to describe prenatal ultrasonography and magnetic resonance imaging (MRI) findings of a thrombosed midline dural venous malformation...
- Molecular MRI of intracranial thrombus in a rat ischemic stroke modelRitika Uppal
Department of Radiology, Massachusetts General Hospital East, 149 13th Street, Suite 2301, Charlestown, MA 02129, USA
Stroke 41:1271-7. 2010..In this study, we examined whether this fibrin-specific MR probe could noninvasively characterize intracranial arterial thrombi...
- Intraarterial reteplase and intravenous abciximab for treatment of acute ischemic stroke. A preliminary feasibility and safety study in a non-human primate modelAdnan I Qureshi
Zeenat Qureshi Stroke Research Center, The University of Medicine and Dentistry of New Jersey, DOC 8100, 90 Bergen Street, Newark, NJ 07103, USA
Neuroradiology 47:845-54. 2005..with intraarterial (IA) administration of a thrombolytic agent (reteplase) in a primate model of intracranial thrombosis. We introduced thrombus through superselective catheterization of the intracranial segment of the ..
- Determination and pharmacokinetic study of taxifolin in rabbit plasma by high-performance liquid chromatographyOlga N Pozharitskaya
Interregional Center Adaptogen, 47 5 Piskarevsky pr, 195067 St Petersburg, Russia
Phytomedicine 16:244-51. 2009..The absolute bioavailability of taxifolin after oral administration of lipid solution was 36%...
- Formation of a Liquid Jet by Interaction between a Laser-induced Bubble and a Shock WaveT Hirano
Department of Neurosurgery Tohoku University Graduate School of Medicine, Shock Wave Research Center Institute of Fluid Science, Tohoku University Sendai, Japan
Interv Neuroradiol 7:35-40. 2001..2 mm, which was nearly twice deeper than the laser irradiation only (2.2 mm). Combination of this liquid jet and fibrinolytics will realize more rapid recanalization with fewer drugs...
- Malignant profile detected by CT angiographic information predicts poor prognosis despite thrombolysis within three hours from symptom onsetVolker Puetz
Department of Neurology, Dresden University Stroke Center, University of Technology Dresden, Dresden, Germany
Cerebrovasc Dis 29:584-91. 2010..We sought to determine whether CT angiography (CTA) could identify a malignant imaging profile within 3 h from symptom onset...
- [Thrombus of the left lateral sinus spreading to the internal jugular vein]J C Lacour
Service de Neurologie, Hopital Neurologique, 54035 Nancy Cedex
Rev Neurol (Paris) 159:451-4. 2003..The time course of the symptoms suggested that intracranial thrombosis occurred first...
- CT angiography in the rapid triage of patients with hyperacute stroke to intraarterial thrombolysis: accuracy in the detection of large vessel thrombusM H Lev
Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114 9657, USA
J Comput Assist Tomogr 25:520-8. 2001..The purpose of this work was to evaluate the accuracy of CT angiography (CTA) for the detection of large vessel intracranial thrombus in clinically suspected hyperacute (<6 h) stroke patients...
- [Headaches in a 21-year-old man with Goodpasture disease]J S Petit
Unité de réanimation polyvalente, Hopital Maison Blanche, 45, rue Cognacq Jay, 51092 Reims Cedex, France
Ann Fr Anesth Reanim 28:799-802. 2009The case of a 21-year old man who died due to an intracranial thrombosis just after diagnosis of Goodpasture's disease, is reported. Discussion deals with the putative mechanisms, which could be responsible for the thrombosis.
- Case report of a patient who underwent thrombolysis of a "silent" thrombus in the middle cerebral arteryTitto T Idicula
Haukeland University Hospital, Bergen, Norway
Neurologist 15:142-3. 2009..Thrombolysis might be beneficial in these patients in spite of the lack of measurable neurologic deficits. We present a patient with a 'silent' thrombus in the middle cerebral artery...
- Outcomes of Perinatal StrokeMeredith Golomb; Fiscal Year: 2008..During the last year of the study, she plans to apply for an R01 grant to set up a pilot clinical trial. [unreadable] [unreadable]..
- Genetic Markers of Thrombosis in Embolic StrokeKaren Furie; Fiscal Year: 2006....
- 26th Princeton Conference on Cerebrovascular DiseaseJames Grotta; Fiscal Year: 2008..All presentations and discussion will be recorded and published. [unreadable] [unreadable] [unreadable]..
- POTASSIUM CHANNELS AND CEREBRAL HEMODYNAMICS AFTER BRAINWilliam Armstead; Fiscal Year: 2005..These studies may lead to therapies for brain injured children. ..
- Ischemic Stroke Treatment with Microbubbles, a Novel Clot Lysis TherapeuticWilliam C Culp; Fiscal Year: 2010..Our proposed pilot study will determine which of these treatments is most successful, and future studies will further explore that treatment. (End of Abstract) ..
- Screening Technology and Outcomes Project in StrokeKaren Furie; Fiscal Year: 2005..abstract_text> ..
- Photothrombotic Brain Infarction and EpileptogenesisKevin Kelly; Fiscal Year: 2005..abstract_text> ..
- CALCIUM BLOCKER AND RELATED THERAPY FOR STROKE RECOVERYJames Grotta; Fiscal Year: 2004....
- Stroke Hospitalization in the Elderly with Medicare FFSJudith Lichtman; Fiscal Year: 2009..These results will help inform decisions about the allocation of adequate resources, and more importantly, help identify opportunities to improve care and prevention of elderly stroke patients. ..
- VASCULAR INTERACTION WITH AGE IN MYOCARDIAL INFARCTIONSteven Schulman; Fiscal Year: 2004..We anticipate that the study findings will suggest the use of new evaluation and therapeutic strategies, which will significantly decrease the age associated mortality and morbidity in post-infarction patients. ..
- RADIATION ARTERIOPATHY IN A TRANSGENIC AV FISTULA MODELMichael Lawton; Fiscal Year: 2004..If NO and TGF-01 are involved in the radiation arteriopathy of AVMs, they might be used to enhance the efficacy of conventional stereotactic radiosurgery as part of a gene therapy for high-grade cerebral AVMs. ..
- Effects of Stress on Pathology of Parkinson's DiseaseGERLINDE METZ; Fiscal Year: 2004..These approaches will provide the opportunity to understand factors involved in the pathology of PD and to develop novel therapeutic strategies for neurodegenerative motor disorders. ..
- Middle Cerebral and Common Artery Occlusion and Poststroke EpilepsyKevin Kelly; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- Safety and Tolerability of Deferoxamine in Acute Cerebral HemorrhageMagdy H Selim; Fiscal Year: 2010..ICH is a frequent cause of disability and death. A successful study demonstrating the efficacy of iron-modifying therapy would be of considerable public health significance. ..
- Plasminogen activators and cerebral ischemic injuryWilliam M Armstead; Fiscal Year: 2010....
- Impact of Aging on Stroke Care: A National PerspectiveJudith Lichtman; Fiscal Year: 2004..We hypothesize that variations in care exist by age. Moreover, these differences in care will not be explained by differences clinical features or co-morbid conditions associated with aging. ..
- PARAMEDIC FIELD INITIATION OF MAGNESIUM NEUROPROTECTIVEJeffrey Saver; Fiscal Year: 2003..abstract_text> ..