Genomes and Genes
transient ischemic attack
Summary: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)
Publications281 found, 100 shown here
- Get With the Guidelines-Stroke is associated with sustained improvement in care for patients hospitalized with acute stroke or transient ischemic attackLee H Schwamm
Massachusetts General Hospital, Boston, MA 02114, USA
Circulation 119:107-15. 2009Adherence to evidence-based guidelines for treatment of stroke or transient ischemic attack is suboptimal. We sought to establish whether participation in Get With the Guidelines-Stroke was associated with improvements in adherence.
- Transient ischemic attack--proposal for a new definitionGregory W Albers
Stanford University School of Medicine Palo Alto, CA 94305, USA
N Engl J Med 347:1713-6. 2002
- Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparisonPeter M Rothwell
Stroke Prevention Research Unit, University Department of Clinical Neurology, Radcliffe Infirmary, Oxford, UK
Lancet 370:1432-42. 2007..Our aim was to determine the effect of more rapid treatment after TIA and minor stroke in patients who are not admitted direct to hospital...
- High-dose atorvastatin after stroke or transient ischemic attackPierre Amarenco
Denis Diderot University, Paris
N Engl J Med 355:549-59. 2006Statins reduce the incidence of strokes among patients at increased risk for cardiovascular disease; whether they reduce the risk of stroke after a recent stroke or transient ischemic attack (TIA) remains to be established.
- Usefulness of ambulatory 7-day ECG monitoring for the detection of atrial fibrillation and flutter after acute stroke and transient ischemic attackDenis Jabaudon
Department of Neurology, University Hospital Geneva, Rue Micheli du Crest 24, 1211 Geneve 4, Switzerland Email
Stroke 35:1647-51. 2004..study, we hypothesized that 7-day ambulatory ECG monitoring using an event-loop recording (ELR) device would detect otherwise occult episodes atrial fibrillation and flutter (AF) after acute stroke or transient ischemic attack (TIA).
- Validation and refinement of scores to predict very early stroke risk after transient ischaemic attackS Claiborne Johnston
Stroke Service, Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
Lancet 369:283-92. 2007....
- Predictive value of stroke and transient ischemic attack discharge diagnoses in The Danish National Registry of PatientsSøren P Johnsen
Department of Epidemiology and Social Medicine, Aarhus University, Vennelyst Boulevard 6, Aarhus C, Denmark
J Clin Epidemiol 55:602-7. 2002We examined the predictive value of the discharge diagnoses of stroke and transient ischemic attack (TIA) in The National Registry of Patients (NRP) for participants in the Danish cohort study "Diet, Cancer, and Health...
- Risk of stroke early after transient ischaemic attack: a systematic review and meta-analysisMatthew F Giles
Stroke Prevention Research Unit, Oxford University Department of Clinical Neurology, Radcliffe Infirmary, Oxford, UK
Lancet Neurol 6:1063-72. 2007..However, reliable estimation of this risk is necessary for planning effective service provision, clinical trials, and public education. We therefore did a systematic review of all studies of stroke risk early after TIA...
- Ambient air pollution and risk for ischemic stroke and transient ischemic attackLynda D Lisabeth
Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109 2029, USA
Ann Neurol 64:53-9. 2008..The objective of this study was to investigate the association between short-term exposure to ambient air pollution and risk for ischemic cerebrovascular events in a US community...
- Prevalence of abnormal glucose tolerance following a transient ischemic attack or ischemic strokeWalter N Kernan
Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520 8025, USA
Arch Intern Med 165:227-33. 2005Despite current preventive therapies, patients with transient ischemic attack (TIA) and ischemic stroke remain at high risk for recurrent brain disease and cardiovascular events...
- Risk of stroke, transient ischemic attack, and vessel occlusion before endarterectomy in patients with symptomatic severe carotid stenosisTill Blaser
Department of Neurology, University of Magdeburg, Magdeburg, Germany
Stroke 33:1057-62. 2002..We aimed to identify and determine the clinical relevance of parameters predictive of stroke recurrence and vessel occlusion before carotid endarterectomy...
- Time course of aquaporin expression after transient focal cerebral ischemia in miceMarlise de Castro Ribeiro
Department of Neurology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
J Neurosci Res 83:1231-40. 2006..The expression of AQP1 remained unchanged. These results suggest that AQP4, but not AQP1 or AQP9, may play an important role in water movement associated with the pathophysiology of edema after transient cerebral ischemia in the mouse...
- Prediction of recurrent stroke and vascular death in patients with transient ischemic attack or nondisabling stroke: a prospective comparison of validated prognostic scoresChristian Weimar
Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
Stroke 41:487-93. 2010..We aimed to prospectively compare the predictive accuracy of the Essen Stroke Risk Score, Stroke Prognostic Instrument, Hankey score, and the Life Long After Cerebral ischemia score...
- Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trialJames Kennedy
Acute Stroke Programme, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
Lancet Neurol 6:961-9. 2007..Patients with transient ischaemic attack (TIA) or minor stroke are at high immediate risk of stroke. The optimum early treatment options for these patients are not known...
- Fibrinogen concentration and risk of ischemic stroke and acute coronary events in 5113 patients with transient ischemic attack and minor ischemic strokePeter M Rothwell
Stroke Prevention Research Unit, University of Oxford, UK
Stroke 35:2300-5. 2004..Fibrinogen is an independent risk factor for coronary events in population-based studies and in patients with coronary heart disease, but there is uncertainty about prediction of stroke, particularly in secondary prevention...
- Microglial activation precedes and predominates over macrophage infiltration in transient focal cerebral ischemia: a study in green fluorescent protein transgenic bone marrow chimeric miceMatthias Schilling
Department of Neurology, Universitatsklinikum Munster, Munster, Germany
Exp Neurol 183:25-33. 2003..GFP bone marrow chimeric mice are a powerful tool to further differentiate the function of resident microglia and hematogenous macrophages following cerebral ischemia...
- Reliability of clinical diagnosis of the symptomatic vascular territory in patients with recent transient ischemic attack or minor strokeEnrico Flossmann
FRCP, Stroke Prevention Research Unit, University Department of Clinical Neurology, Level 6, West Wing, The John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
Stroke 39:2457-60. 2008Knowledge of the vascular territory of a recent transient ischemic attack or minor stroke determines appropriate investigations and the need for territory-specific interventions such as endarterectomy and stenting...
- Carotid plaque inflammation is associated with cerebral microembolism in patients with recent transient ischemic attack or stroke: a pilot studyRamez Reda Moustafa
Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
Circ Cardiovasc Imaging 3:536-41. 2010..We hypothesized that microembolic signals (MES) on transcranial Doppler will be associated with carotid plaque inflammation on (18)F fluorodeoxyglucose positron-emission tomography (FDG PET) in recently symptomatic patients...
- Secondary prevention of stroke and transient ischemic attack: is more platelet inhibition the answer?James K Liao
Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, 65 Landsdowne St, Rm 275, Cambridge, MA 02139, USA
Circulation 115:1615-21. 2007..200,000 of the 700,000 strokes reported annually in the United States, which makes secondary stroke prevention an important goal in the management of disease among patients who have experienced stroke or transient ischemic attack.
- Plasma concentration of C-reactive protein and risk of ischemic stroke and transient ischemic attack: the Framingham studyN S Rost
National Heart, Lung, and Blood Institute's Framingham Study, Framingham, Massachusetts, USA
Stroke 32:2575-9. 2001..We related plasma CRP levels to incidence of first ischemic stroke or transient ischemic attack (TIA) in the Framingham Study original cohort...
- Characteristics, performance measures, and in-hospital outcomes of the first one million stroke and transient ischemic attack admissions in get with the guidelines-strokeGregg C Fonarow
University of California, Los Angeles, USA
Circ Cardiovasc Qual Outcomes 3:291-302. 2010..this burden, Get With The Guideline (GWTG)-Stroke was developed to facilitate the measurement, tracking, and improvement in quality of care and outcomes for acute stroke and transient ischemic attack (TIA) patients in the United States.
- Clopidogrel plus aspirin versus aspirin alone for reducing embolisation in patients with acute symptomatic cerebral or carotid artery stenosis (CLAIR study): a randomised, open-label, blinded-endpoint trialKa Sing Lawrence Wong
Departments of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
Lancet Neurol 9:489-97. 2010..We aimed to investigate whether treatment with clopidogrel plus aspirin reduced the number of microembolic signals detected with transcranial doppler ultrasound compared with aspirin alone in patients with recent stroke...
- Hospital treatment of patients with ischemic stroke or transient ischemic attack using the "Get With The Guidelines" programKenneth A Labresh
MassPRO, Waltham, MA 02451, USA
Arch Intern Med 168:411-7. 2008..Adherence to evidence-based interventions for hospitalized patients who have experienced a stroke is suboptimal. We examined the association of process improvement and Internet-based data collection and decision support with stroke care...
- Chronic atrial fibrillation: Incidence, prevalence, and prediction of stroke using the Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack (CHADS2) risk stratification schemeStephan Rietbrock
General Practice Research Database, Medicines and Health Care Products Regulatory Agency, London, United Kingdom
Am Heart J 156:57-64. 2008..The aim of the study is to estimate the incidence and prevalence of chronic AF (cAF) in the United Kingdom and test the accuracy of the CHADS2 score for stroke prediction...
- A population-based study of the prevalence of fatigue after transient ischemic attack and minor strokeCharlotte Winward
Movement Science Group, Oxford Brookes University, Oxford, UK
Stroke 40:757-61. 2009....
- Medical (nonsurgical) intervention alone is now best for prevention of stroke associated with asymptomatic severe carotid stenosis: results of a systematic review and analysisAnne L Abbott
Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
Stroke 40:e573-83. 2009....
- Risk of myocardial infarction and vascular death after transient ischemic attack and ischemic stroke: a systematic review and meta-analysisEmmanuel Touze
Department of Neurology, Hopital Sainte Anne, Universite Paris Descartes, Faculte de Medecine, Paris Cedex 14
Stroke 36:2748-55. 2005..a systematic review and a meta-analysis to determine the risk of MI and nonstroke vascular death after transient ischemic attack (TIA) and ischemic stroke...
- A simple score (ABCD) to identify individuals at high early risk of stroke after transient ischaemic attackP M Rothwell
Department of Clinical Neurology, University of Oxford, Radcliffe Infirmary, Oxford, OX2 6HE, UK
Lancet 366:29-36. 2005..Effective early management of patients with transient ischaemic attacks (TIA) is undermined by an inability to predict who is at highest early risk of stroke...
- Incidence and short-term prognosis of transient ischemic attack in a population-based studyDawn Kleindorfer
Department of Emergency Medicine, University of Cincinnati, Ohio, USA
Stroke 36:720-3. 2005..We present the incidence and short-term prognosis of TIA within a large population with a significant proportion of minorities with out-of-hospital TIA...
- Early risk of stroke after transient ischemic attack: a systematic review and meta-analysisCaren M Wu
Department of Medicine, University of Calgary, Calgary, AB, Canada
Arch Intern Med 167:2417-22. 2007Recent observational studies suggest that the risk for stroke may be high in the first 90 days after transient ischemic attack (TIA). This finding may, however, not be consistent across existing studies assessing stroke risk after TIA...
- Serial MRI after transient focal cerebral ischemia in rats: dynamics of tissue injury, blood-brain barrier damage, and edema formationT Neumann-Haefelin
Department of Radiology, Lucas MRS MRI Center, Stanford Stroke Center, Stanford University, CA, USA
Stroke 31:1965-72; discussion 1972-3. 2000....
- Timecourse of health-related quality of life as determined 3, 6 and 12 months after stroke. Relationship to neurological deficit, disability and depressionInga H Suenkeler
Neurological Hospital, Hubertus Str 3 7, 35619 Braunfels, Germany
J Neurol 249:1160-7. 2002..Variables were identified that may predict poststroke life satisfaction...
- MRI findings may predict early neurologic deterioration in acute minor stroke or transient ischemic attack due to intracranial atherosclerosisJoon Tae Kim
Department of Neurology, Chonnam National University Hospital, Gwangju, Republic of Korea
Eur Neurol 64:95-100. 2010..Although minor stroke and transient ischemic attack (TIA) seem benign, their occurrence in patients with ICAS may lead to early neurological deterioration (..
- Diffusion-weighted MRI in 300 patients presenting late with subacute transient ischemic attack or minor strokeUrsula G Schulz
Stroke Prevention Research Unit, Department of Clinical Neurology, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
Stroke 35:2459-65. 2004Many patients with transient ischemic attack (TIA) or minor stroke present to medical attention after a delay of several days or weeks, at which time it may be more difficult to obtain a clear history and clinical signs may have resolved...
- Is this patient having a stroke?Larry B Goldstein
Department of Medicine, Duke Center for Cerebrovascular Disease, Durham, NC 27710, USA
JAMA 293:2391-402. 2005Patients suspected of having a stroke or transient ischemic attack require accurate assessment for appropriate acute treatment and use of secondary preventive interventions.
- Agreement regarding diagnosis of transient ischemic attack fairly low among stroke-trained neurologistsJames Castle
Department of Neurology, NorthShore University Healthsystem, Pritzker School of Medicine, Evanston, Ill, USA
Stroke 41:1367-70. 2010Agreement between physicians to define the likelihood of a transient ischemic attack (TIA) remains poor...
- Prediction of major vascular events in patients with transient ischemic attack or ischemic stroke: a comparison of 7 modelsAnnemarie D Wijnhoud
Departments of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
Stroke 41:2178-85. 2010..In patients with a recent TIA or minor stroke, prediction of long-term risk of major vascular events is important, but difficult. We aimed to study the external validity of currently available prediction models...
- Crescendo transient Aura attacks: a transient ischemic attack mimic caused by focal subarachnoid hemorrhageAaron Izenberg
Dr Thomas and Harriet Black Acute TIA Unit and Regional Stroke Prevention Clinic, Division of Neurology and Brain Sciences Program, Sunnybrook Health Sciences Centre, Department of Medicine, University of Toronto, Toronto, Toronto, Ontario Canada
Stroke 40:3725-9. 2009Diagnosis of transient ischemic attack can be difficult because many mimics exist. We report the clinical and neuroimaging features of a distinct hemorrhagic transient ischemic attack mimic.
- Joint effects of risk factors for stroke and transient ischemic attack in a German population: the EPIC Potsdam StudyCornelia Weikert
Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558, Nuthetal, Germany
J Neurol 254:315-21. 2007..The aim of the present study was to assess single and joint effects of risk factors on the incidence of stroke and TIA and to compare their magnitudes in a large population-based German cohort...
- Watershed infarcts in transient ischemic attack/minor stroke with > or = 50% carotid stenosis: hemodynamic or embolic?Ramez R Moustafa
Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
Stroke 41:1410-6. 2010..However, no study so far has directly addressed these conflicting scenarios...
- Blood test detecting autoantibodies to N-methyl-D-aspartate neuroreceptors for evaluation of patients with transient ischemic attack and strokeSvetlana A Dambinova
Department of Neurology and Neurosurgery, I P Pavlov s State Medical University, 6 8 Tolstoj Str, St Petersburg, Russia 197102
Clin Chem 49:1752-62. 2003..investigated the diagnostic accuracy of serum aAbs to NR2A/2B, a subtype of NMDA receptors, in assessing transient ischemic attack (TIA) and ischemic stroke (IS) and its ability to distinguish cerebral ischemia from intracerebral ..
- High prevalence of stroke symptoms among persons without a diagnosis of stroke or transient ischemic attack in a general population: the REasons for Geographic And Racial Differences in Stroke (REGARDS) studyVirginia J Howard
Department of Epidemiology, University of Alabama at Birmingham School of Public Health, 1665 University Blvd, Birmingham, AL 35294 0022, USA
Arch Intern Med 166:1952-8. 2006..This study assessed the prevalence of stroke symptoms in a stroke- and transient ischemic attack (TIA)-free population and the association of symptoms with risk factors indexed by the Framingham Stroke ..
- Headache at stroke onset in 2196 patients with ischemic stroke or transient ischemic attackSusanne Tentschert
University Clinic of Neurology, Clinical Department of Clinical Neurology, University of Vienna, Austria
Stroke 36:e1-3. 2005..Headache is a common symptom in acute ischemic and hemorrhagic stroke, but many aspects of its association with other clinical factors are controversial...
- Strong independent correlation of proteinuria with cerebral microbleeds in patients with stroke and transient ischemic attackBruce Ovbiagele
Department ofNeurology, StrokeCenter, University ofCalifornia, Los Angeles, CA 90095, USA
Arch Neurol 67:45-50. 2010..To assess the association of proteinuria with the frequency and number of cerebral microbleeds (CMB), a harbinger of future hemorrhagic stroke...
- Midazolam challenge reinduces neurological deficits after transient ischemic attackRonald M Lazar
From the Columbia University College of Physicians and Surgeons, Columbia Presbyterian Medical Center, New York, NY, USA
Stroke 34:794-6. 2003A transient ischemic attack (TIA) in the brain is classically considered a syndrome lasting <24 hours...
- Temporary middle cerebral artery occlusion in the rat: consistent protocol for a model of stroke and reperfusionB S Aspey
Reta Lila Weston Institute of Neurological Studies, UCL Medical School, London, UK
Neuropathol Appl Neurobiol 26:232-42. 2000....
- Clinical and radiological features of childhood cerebral infarction following varicella zoster virus infectionElena Miravet
Neurology Department, Great Ormond Street Hospital for Children NHS Trust, London, UK
Dev Med Child Neurol 49:417-22. 2007..A more comprehensive diagnostic evaluation should be considered in children with AIS who do not fit the clinical and radiological profile outlined, even where there is a history of recent VZV infection...
- Systematic review and pooled analysis of published and unpublished validations of the ABCD and ABCD2 transient ischemic attack risk scoresMatthew F Giles
Stroke Prevention Research Unit, NIHR Biomedical Research Centre, Oxford University Department of Clinical Neurology, John Radcliffe Hospital, Oxford, UK
Stroke 41:667-73. 2010The ABCD system was derived to predict early risk of stroke after transient ischemic attack. Independent validations have reported conflicting results...
- Prognosis in patients with transient ischaemic attack (TIA) and minor stroke attending TIA services in the North West of England: the NORTHSTAR StudyJ R Selvarajah
Department of Neurology, Leeds General Infirmary, Leeds, UK
J Neurol Neurosurg Psychiatry 79:38-43. 2008..We investigated prognosis, and the use of the ABCD2 score, in patients attending TIA services in the North West of England with a diagnosis of TIA or minor stroke...
- Chickenpox and stroke in childhood: a study of frequency and causationR Askalan
Hospital for Sick Children and the University of Toronto, Toronto, Canada
Stroke 32:1257-62. 2001..Varicella-associated AIS has characteristic features, including a 2-fold increase in recurrent AIS and transient ischemic attacks. Varicella is an important risk factor for childhood AIS...
- Recurrent events in transient ischemic attack and minor stroke: what events are happening and to which patients?Shelagh B Coutts
Department of Clinical Neurosciences, Room C1246, Foothills Medical Centre, 1403 29th St SW, Calgary, AB, T2N 2T9, Canada
Stroke 39:2461-6. 2008The risk of a recurrent stroke after transient ischemic attack (TIA) or minor stroke is high. Clinical trials are needed to assess acute treatment options in these patients...
- Detection of diffusion-weighted MRI abnormalities in patients with transient ischemic attack: correlation with clinical characteristicsRalph A Crisostomo
Stanford Medical School, Palo Alto, CA, USA
Stroke 34:932-7. 2003..We assessed the utility of DWI in patients with transient ischemic attack (TIA) to further evaluate the usefulness of this technique in these individuals.
- Yield of systematic transcranial Doppler in patients with transient ischemic attackElena Meseguer
INSERM U698 and Denis Diderot University and Medical School, Paris, France
Ann Neurol 68:9-17. 2010Urgent evaluation and treatment of transient ischemic attack (TIA) patients in a dedicated TIA clinic may reduce the 90-day stroke risk by 80%...
- Retrospective study of total healthcare costs associated with chronic nonvalvular atrial fibrillation and the occurrence of a first transient ischemic attack, stroke or major bleedStephen J Boccuzzi
IMS Health, Plymouth Meeting, PA, USA
Curr Med Res Opin 25:2853-64. 2009..To determine the direct healthcare costs associated with the onset of chronic nonvalvular atrial fibrillation (CNVAF), warfarin utilization and the occurrence of cerebrovascular events in a commercially-insured population...
- Transient ischemic attack and stroke can be differentiated by analyzing early diffusion-weighted imaging signal intensity changesKerstin Winbeck
Department of Neurology, Technical University of Munich, Möhlstr 28, 81675 Munich, Germany
Stroke 35:1095-9. 2004..Signal intensity changes occur not only in patients with definite stroke but also in up to 67% of transient ischemic attack (TIA) patients...
- Triaging transient ischemic attack and minor stroke patients using acute magnetic resonance imagingShelagh B Coutts
Seaman Family MR Research Centre, Foothills Medical Centre, Calgary Health Region, Calgary, Alberta, Canada
Ann Neurol 57:848-54. 2005..imaging (DWI) lesions and vessel occlusion on acute brain magnetic resonance images of minor stroke and transient ischemic attack patients predicted the occurrence of subsequent stroke and functional outcome...
- Is the ABCD score useful for risk stratification of patients with acute transient ischemic attack?Brett L Cucchiara
Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
Stroke 37:1710-4. 2006A 6-point scoring system (ABCD) was described recently for stratifying risk after transient ischemic attack (TIA). This score incorporates age (A), blood pressure (B), clinical features (C), and duration (D) of TIA...
- Population-based study of ABCD2 score, carotid stenosis, and atrial fibrillation for early stroke prediction after transient ischemic attack: the North Dublin TIA studyOrla C Sheehan
Neurovascular Clinical Science Unit, Mater University Hospital University College Dublin, Ireland
Stroke 41:844-50. 2010b>Transient ischemic attack (TIA) etiologic data and the ABCD(2) score may improve early stroke risk prediction, but studies are required in population-based cohorts...
- Pioglitazone improves insulin sensitivity among nondiabetic patients with a recent transient ischemic attack or ischemic strokeWalter N Kernan
Department of Medicine, Yale University School of Medicine, PO Box 208025, New Haven, CT 06520 8025, USA
Stroke 34:1431-6. 2003..the effectiveness of pioglitazone compared with placebo for improving insulin sensitivity among nondiabetic patients with a recent transient ischemic attack (TIA) or nondisabling ischemic stroke and impaired insulin sensitivity.
- Inherited prothrombotic risk factors in children with stroke, transient ischemic attack, or migraineDésirée Coen Herak
Clinical Institute of Laboratory Diagnosis, Clinical Hospital Center Zagreb, Zagreb University School of Medicine, Kispaticeva 12, Zagreb 10000, Croatia
Pediatrics 123:e653-60. 2009The aim of this study was to investigate the prevalence and possible association of inherited prothrombotic risk factors in children with stroke, transient ischemic attack, or migraine.
- When to expect negative diffusion-weighted images in stroke and transient ischemic attackP N Sylaja
Calgary Stroke Program, Department of Clinical Neurosciences, Foothills Medical Centre, Room 1162, University of Calgary, Alberta, Canada
Stroke 39:1898-900. 2008..The frequency of DWI negative cerebral ischemia and clinical factors associated with such a circumstance is not well understood...
- Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or bothJ L Mas
Department of Neurology, Sainte Anne Hospital, Paris V University, Paris, France
N Engl J Med 345:1740-6. 2001..We studied the risks of recurrent cerebrovascular events associated with these cardiac abnormalities...
- Diagnostic usefulness of the ABCD2 score to distinguish transient ischemic attack and minor ischemic stroke from noncerebrovascular events: the North Dublin TIA StudyOrla C Sheehan
Neurovascular Clinical Science Unit, Mater University Hospital, University College Dublin, Dublin, Ireland
Stroke 40:3449-54. 2009b>Transient ischemic attack (TIA) diagnosis is frequently difficult in clinical practice. Noncerebrovascular symptoms are often misclassified as TIA by nonspecialist physicians...
- Inadequate acoustical temporal bone window in patients with a transient ischemic attack or minor stroke: role of skull thickness and bone densityAnnemarie D Wijnhoud
Department of Neurology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Ultrasound Med Biol 34:923-9. 2008..may provide important diagnostic and prognostic information in patients with ischemic stroke or transient ischemic attack. TCD also enhances the effect of thrombolytic treatment in patients with acute stroke...
- Accuracy of paramedic identification of stroke and transient ischemic attack in the fieldW S Smith
Department of Neurology, University of California, San Francisco 94143 0114, USA
Prehosp Emerg Care 2:170-5. 1998..To determine the accuracy of acute stroke identification by paramedics in an urban emergency medical services system...
- Persistent hyperfibrinogenemia in acute ischemic stroke / transient ischemic attack (TIA)Shani Shenhar-Tsarfaty
Department of Neurology, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Thromb Haemost 99:169-73. 2008..Prompt and long-term, rather than short term, interventions to reduce the concentrations of this protein might therefore be of relevance...
- Very early risk of stroke after a first transient ischemic attackJ K Lovett
Stroke Prevention Research Unit, Department of Clinical Neurology, Radcliffe Infirmary, Woodstock Rd, Oxford OX2 6HE UK
Stroke 34:e138-40. 2003The commonly quoted early risks of stroke after a first transient ischemic attack (TIA)-1% to 2% at 7 days and 2% to 4% at 1 month-are likely to be underestimates because of the delay before inclusion into previous studies and the ..
- Effects of an individualized multimedia computer program for health education in patients with a recent minor stroke or transient ischemic attack - a randomized controlled trialE Maasland
Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
Acta Neurol Scand 115:41-8. 2007b>Transient ischemic attack (TIA) and stroke patients often show a striking lack of knowledge about their disease...
- Long-term mortality and risk of stroke after transient ischemic attack: a hospital-based cohort studyChristian Weimar
Dept of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
J Neurol 256:639-44. 2009Stroke and mortality rates in patients with transient ischemic attack (TIA) differ widely between community-based studies and research cohorts...
- Diagnosis and initial management of stroke and transient ischemic attack across UK health regions from 1992 to 1996: experience of a national primary care databaseR G Gibbs
Department of Vascular Surgery, Imperial College School of Medicine, Charing Cross Campus, London, UK
Stroke 32:1085-90. 2001..burden of cerebrovascular disease across the different health regions of the United Kingdom and to determine whether the initial management of new cases of stroke and transient ischemic attack (TIA) was uniform across the United Kingdom:
- Increased risk of stroke and transient ischemic attack in 5-year survivors of Hodgkin lymphomaMarie L De Bruin
Department of Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
J Natl Cancer Inst 101:928-37. 2009Information on clinically verified stroke and transient ischemic attack (TIA) following Hodgkin lymphoma is scarce...
- Relation between the metabolic syndrome and ischemic stroke or transient ischemic attack: a prospective cohort study in patients with atherosclerotic cardiovascular diseaseN Koren-Morag
Division of Epidemiology, Sackler Medical Faculty, Tel Aviv University, Israel
Stroke 36:1366-71. 2005..We explored the relation of metabolic syndrome versus frank diabetes with first-ever ischemic stroke or transient ischemic attack (TIA) in a large cohort of patients with atherosclerotic cardiovascular disease.
- Medium-term variability of blood pressure and potential underdiagnosis of hypertension in patients with previous transient ischemic attack or minor strokeRobert L Cuffe
Stroke Prevention Research Unit, Department of Clinical Neurology, University of Oxford, Oxford, England
Stroke 37:2776-83. 2006..The extent of medium-term variability in BP is most marked in patients with a previous transient ischemic attack (TIA) or stroke...
- Clinical inquiries. Is an outpatient workup safe for patients with a transient ischemic attack?Melissa Franklin
Moses Cone Family Practice Residency, Greensboro, NC, USA
J Fam Pract 53:567-9. 2004
- Current management of transient ischemic attackPadmavathy N Sylaja
Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
Am J Cardiovasc Drugs 7:67-74. 2007b>Transient ischemic attack (TIA) is a precursor to ischemic stroke. At least half of patients with TIA have a new, small ischemic lesion demonstrable on magnetic resonance imaging using a diffusion weighted sequence...
- Patients with transient ischemic attack or minor stroke should be admitted to hospital: forGeoffrey A Donnan
Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada
Stroke 37:1137-8. 2006
- Morphology of the patent foramen ovale in asymptomatic versus symptomatic (stroke or transient ischemic attack) patientsSachin S Goel
Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA
Am J Cardiol 103:124-9. 2009..differences in the anatomy of PFOs on TEE in patients with and without recurrent cryptogenic stroke or transient ischemic attack. The results of TEE in 58 patients who had PFO closure for cryptogenic cerebrovascular accident (CVA) ..
- Transient ischemic attack patients with fluctuations are at highest risk for early strokeAnastasios Chatzikonstantinou
Department of Neurology, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Mannheim, Germany
Cerebrovasc Dis 27:594-8. 2009..The management and risk of early stroke are unclear in patients with fluctuating neurological symptoms. We aimed to evaluate the clinical course of these patients presenting within 24 h after onset of acute cerebral ischemia symptoms...
- Sleep apnea in patients with transient ischemic attack and minor stroke: opportunity for risk reduction of recurrent stroke?Wesley Chan
Calgary Stroke Program, Faculty of Medicine, University of Calgary, Alberta, Canada
Stroke 41:2973-5. 2010..Obstructive sleep apnea (OSA) may increase this risk. The objectives of our study were to determine the prevalence and severity of OSA and its clinical presentation in this population...
- Survey of blood pressure control status in patients with ischemic stroke or transient ischemic attack in ChinaYilong Wang
Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
Neurol Res 30:348-55. 2008We sought to assess the current status of blood pressure control and the use of antihypertensive drugs in patients with ischemic stroke (IS) or transient ischemic attack (TIA) in China.
- Low vitamin B6 but not homocyst(e)ine is associated with increased risk of stroke and transient ischemic attack in the era of folic acid grain fortificationPeter J Kelly
Stroke Service, Department of Neurology, VBK 802, Massachusetts General Hospital, Fruit St, Boston, MA 02114, USA
Stroke 34:e51-4. 2003..We performed a case-control study to determine the risk of stroke and transient ischemic attack (TIA) associated with tHcy and low vitamin status in a postfortification US sample.
- The association of transient ischemic attack symptoms with memory impairment among elderly participants of the Third US National Health and Nutrition Examination SurveyPaul Y Takahashi
Department of Internal Medicine, Division of Primary Care Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Geriatr Psychiatry Neurol 22:46-51. 2009..Stroke is a well-known risk factor for vascular dementia. However, the association of transient ischemic attacks with cognitive impairment is less well-established...
- Identification of culprit lesions after transient ischemic attack by combined 18F fluorodeoxyglucose positron-emission tomography and high-resolution magnetic resonance imagingJohn R Davies
Division of Cardiovascular Medicine, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
Stroke 36:2642-7. 2005..In this study, plaque inflammation was quantified before endarterectomy using the combination of 18F fluorodeoxyglucose positron (FDG)-emission tomography (PET) and high-resolution MRI (HRMRI)...
- Limb shaking transient ischemic attack--an unusual presentation of carotid occlusive disease. A case report and review of the literatureA B M Salah Uddin
Seton Hall University School of Graduate Medical Education, South Orange, NJ 07079, USA
Parkinsonism Relat Disord 10:451-3. 2004Limb shaking transient ischemic attack (TIA) is an uncommon presentation of carotid occlusive disease. This unusual form of TIA is not well recognized and may be mistaken for focal epilepsy, delaying proper diagnosis and treatment...
- Frequency and determinants of lipid testing in ischemic stroke and transient ischemic attack: findings from get with the guidelines-strokeEric E Smith
Calgary Stroke Program, University of Calgary, Alberta, Canada
Stroke 41:232-8. 2010National guidelines recommend lipid testing for all patients with ischemic stroke and transient ischemic attack. This study examined the frequency and predictors for in-hospital low-density lipoprotein testing using data from a ..
- Symptom progression or fluctuation in transient ischemic attack patients predicts subsequent strokeMakoto Nakajima
Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Suita, Japan
Cerebrovasc Dis 29:221-7. 2010The aim of this study was to investigate whether progression or fluctuation of transient ischemic attack (TIA) symptoms is a predictor of subsequent stroke.
- Optimal dosing of intravenous unfractionated heparin bolus in transient ischemic attack or strokeKyusik Kang
Department of Neurology, Eulji General Hospital, Seoul, corrected Republic of Korea
Clin Appl Thromb Hemost 16:126-31. 2010..partial thromboplastin time over the first 6-hour period in a cohort of 54 patients admitted with transient ischemic attack or stroke...
- Implementation of an emergency department based transient ischemic attack clinical pathway: a pilot study in knowledge translationMichael D Brown
Grand Rapids MERC Michigan State University Program in Emergency Medicine, Grand Rapids, MI, USA
Acad Emerg Med 14:1114-9. 2007To assess the feasibility of implementing an emergency department (ED)-based transient ischemic attack (TIA) clinical pathway that uses computer-based clinical support, and to evaluate measures of quality, safety, and efficiency.
- Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attackHisatomi Arima
George Institute for International Health, University of Sydney, Australia
Stroke 36:2164-9. 2005..The primary objective here is to determine whether routine blood pressure-lowering provides additional protection for this high-risk patient group...
- Transient ischemic attack reported with paroxetine useGail H Manos
Department of Psychiatry, Naval Medical Center Portsmouth, Portsmouth, VA 23708 2197, USA
Ann Pharmacother 38:617-20. 2004To report the occurrence of a transient ischemic attack (TIA) temporally related to the initiation of paroxetine.
- Ischemic preconditioning is mediated by erythropoietin through PI-3 kinase signaling in an animal model of transient ischemic attackSamit Malhotra
Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
J Neurosci Res 83:19-27. 2006..By using a middle cerebral artery occlusion (MCAo) model of transient ischemic attack (TIA), we sought to determine whether EPO is required for IP in the protective response against focal ..
- Transient ischemic attack: definition and natural historyLouis R Caplan
Cerebrovascular Disease Service, Palmer 127, West Campus, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
Curr Atheroscler Rep 8:276-80. 2006The standard definition of a transient ischemic attack--"a cerebral dysfunction of an ischemic nature lasting no longer than 24 hours with a tendency to recur"--was arrived at arbitrarily and is no longer tenable...
- Prognostic value of the ABCD2 score beyond short-term follow-up after transient ischemic attack (TIA)--a cohort studyKatrin Holzer
Department of Neurology, Klinikum rechts der Isar, Technische Universitat, Munich, Germany
BMC Neurol 10:50. 2010b>Transient ischemic attack (TIA) patients are at a high vascular risk. Recently the ABCD2 score was validated for evaluating short-term stroke risk after TIA...
- Early stroke risk after transient ischemic attack among individuals with symptomatic intracranial artery stenosisBruce Ovbiagele
Stroke Center and Department of Neurology, UCLA Medical Center, University of California at Los Angeles, 710 Westwood Plaza, Los Angeles, CA 90095, USA
Arch Neurol 65:733-7. 2008Little is known about short-term vascular risk after transient ischemic attack (TIA) caused by intracranial atherosclerosis.
- Patients enrolled in large randomized clinical trials of antiplatelet treatment for prevention after transient ischemic attack or ischemic stroke are not representative of patients in clinical practice: the Netherlands Stroke SurveyLisette Maasland
Van Weel Bethesda Hospital, Department of Neurology, Stationsweg 22, 3247 BW Dirksland, The Netherlands
Stroke 40:2662-8. 2009..use of antiplatelet drugs in reducing the risk of new vascular events in patients with a recent transient ischemic attack or ischemic stroke...
- Early stroke risk after a transient ischemic attack: can it be minimized?Jonathan Y Streifler
Stroke 39:1655-6. 2008
- Cerebral microhemorrhages predict new disabling or fatal strokes in patients with acute ischemic stroke or transient ischemic attackJean Martin Boulanger
Clinique Neuro Rive Sud, 4896 Blvd Taschereau 250, Greenfield Park, Provinvr of Quebec, Canada, J4V 2J2
Stroke 37:911-4. 2006..Cerebral microhemorrhages (MHs) are common among patients presenting with acute ischemic stroke and may predict both subsequent ischemic and hemorrhagic strokes...
- ABCD2 score predicts severity rather than risk of early recurrent events after transient ischemic attackArvind Chandratheva
Stroke Prevention Research Unit, Oxford University Department of Clinical Neurology, John Radcliffe Hospital, Oxford, England
Stroke 41:851-6. 2010The ABCD(2) score predicts the early risk of stroke after transient ischemic attack (TIA). However, data on the severity of recurrent events would also be useful...
- The incidence of sleep apnea in patients with stroke or transient ischemic attackA Wierzbicka
Department of Clinical Neurophysiology, Institute of Psychiatry and Neurology, Warsaw, Poland
J Physiol Pharmacol 57:385-90. 2006..The present study evaluated the frequency of SDB in patients with stroke or transient ischemic attack transient ischemic attack. We studied 43 patients (mean age 68.5 +/-11...
- Intra-arterial thrombin injection of an ascending aortic pseudoaneurysm complicated by transient ischemic attack and rescued with systemic abciximabP H Lin
Division of Vascular Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA
J Vasc Surg 34:939-42. 2001..However, the procedure was complicated by a sudden transient ischemic attack caused by thrombus propagation into the cerebral circulation...
- Hemodynamic and metabolic changes in transient ischemic attack patients: a magnetic resonance angiography and (1)H-magnetic resonance spectroscopy study performed within 3 days of onset of a transient ischemic attackRobertus H C Bisschops
Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
Stroke 33:110-5. 2002We investigated whether patients with transient ischemic attack (TIA) have systemic low flow to the brain or an abnormal intracranial flow distribution caused by an abnormal anatomy of the circle of Willis...
- Cerebrovascular Disease and its Consequences in the Strong Study CohortDedra S Buchwald; Fiscal Year: 2013..white matter hyperintensities, infarcts, and hemorrhages, in populations without known stroke or transient ischemic attack. Further, overt CBVD, such as stroke, was strikingly less common than covert MRI-defined brain disease...
- Insulin Resistance Intervention after Stroke (IRIS) TrialWalter N Kernan; Fiscal Year: 2013Among millions of persons worldwide who survive an ischemic stroke or transient ischemic attack (TIA) each year, a major source of morbidity and mortality is recurrent stroke and myocardial infarction...
- APOPTOSIS OF SMOOTH MUSCLE CELLS IN CAROTID PLAQUESDevendra K Agrawal; Fiscal Year: 2013..RELEVANCE: Many patients with blockade of their neck artery develop neurological symptoms including transient ischemic attack or stroke. This is primarily due to breaking off the atherosclerotic plaque in the neck artery...
- Sleep Apnea in TIA: Reducing Cardiovascular Risk with Positive Airway PressureHenry Klar Yaggi; Fiscal Year: 2012..Patients with transient ischemic attack (TIA) have a high prevalence of sleep apnea (60-80%), and they are at high risk within 1 year for ..
- Blood Transfusions: Gender Differences in Utilization, Predictors, and OutcomesMary A M Rogers; Fiscal Year: 2010..regarding blood transfusion, infection, and thrombotic events (deep-vein thrombosis, pulmonary embolism, transient ischemic attack, stroke, and myocardial infarction) will be extracted from CMS files...
- Predictive optimal anticlotting treatment for segmented patient populationsPeter J Tonellato; Fiscal Year: 2013..S. with over 140,000 deaths annually. The majority of stroke incidences are due to ischemia (87%) or transient ischemic attack (TIA, ~5-10%) and are typically managed by the use of anticlotting drugs including anticoagulants (e.g...
- Targeted management intervention for African-American men with TIA or strokeMARTHA X SAJATOVIC; Fiscal Year: 2013..Interventions targeted to those AA men who have had transient ischemic attack (TIA) or a milder first-time stroke (FTS) may be particularly well-timed as some individuals experience ..
- Klotho and the pathogenesis of cardiovascular diseaseRichard D Semba; Fiscal Year: 2013..disease (myocardial infarction, angina, stroke, congestive heart failure, peripheral artery disease, transient ischemic attack), carotid intima-media thickness, brachial flow-mediated dilation, cardiovascular events and mortality ..
- Atrial Fibrillation Precursors May Be Novel Stroke Risk FactorsHooman Kamel; Fiscal Year: 2013..diagnoses of paroxysmal supraventricular tachycardia are associated with the risk of stroke after transient ischemic attack. This aim will be pursued using a validated ICD-9-CM code for paroxysmal supraventricular tachycardia ..
- Cardiovascular Health Study - Transition Phase - RenewalRichard A Kronmal; Fiscal Year: 2009..new CVD events (including incident myocardial infarction, angina, congestive heart failure, stroke, transient ischemic attack, peripheral arterial disease, and death)...
- Cardiovascular Health Study - Transition Phase - RenewalRichard A Kronmal; Fiscal Year: 2011..new CVD events (including incident myocardial infarction, angina, congestive heart failure, stroke, transient ischemic attack, peripheral arterial disease, and death)...
- Cardiovascular Health Study - Transition Phase - RenewalRichard A Kronmal; Fiscal Year: 2010..new CVD events (including incident myocardial infarction, angina, congestive heart failure, stroke, transient ischemic attack, peripheral arterial disease, and death)...
- Asymptomatic Carotid Stenosis: Cognitive Function and Plaque CorrelatesBrajesh K Lal; Fiscal Year: 2013..who are currently labeled as "asymptomatic" in the absence of a focal neurologic deficit (stroke, transient ischemic attack)...
- UK NETT Clinical Site HubROGER LOYD HUMPHRIES; Fiscal Year: 2013..placebo in acute ischemic stroke), POINT (clopidogrel loading for stroke prevention after transient ischemic attack), and ProTECT (progesterone v. placebo in traumatic brain injury)...
- Role for MicroRNAs in Ischemic ToleranceJulie Anne Saugstad; Fiscal Year: 2012..Clinical evidence suggests that endogenous preconditioning triggered by a transient ischemic attack is present in the human brain...
- Impact of Bariatric Surgery on Long-term Diabetes Remission and ComplicationsDAVID ERIC ARTERBURN; Fiscal Year: 2013..i) cardiac ischemia, infarction, angioplasty/stent, or coronary bypass surgery;(ii) stroke or transient ischemic attack and (iii) peripheral vascular disease-related ulceration, revascularization or amputation This study ..
- Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and StrokeSepideh Amin-Hanjani; Fiscal Year: 2012..abstract_text> ..
- Digital Assistant Supported Medication Adherence and Medical Monitoring SystANTHONY STERNS; Fiscal Year: 2009..Eligible ischemic stroke and transient ischemic attack (TIA) patients undergoing acute treatment at a regional hospital will be approached for consent and then ..
- Developing a Rational Clinical Approach to the Disposition of TIA Cases in the EDMathew Reeves; Fiscal Year: 2009DESCRIPTION (provided by applicant): Transient Ischemic Attack (TIA) or mini-stroke is an episode of acute focal neurological symptoms that lasts less than 24 hours...
- Neuronal Injury and Blood GenomicsFrank Sharp; Fiscal Year: 2005..proposal will determine whether short durations of global cerebral ischemia, focal cerebral ischemia (transient ischemic attack), hypoglycemia and seizures produce different white blood cell genomic responses in rats that can be ..
- Carotid Revascularization Endarterectomy vs Stenting TrialThomas G Brott; Fiscal Year: 2010..carotid artery (>50% by angiogram or >70% by ultrasound for symptomatic disease in patients with transient ischemic attack or ipsilateral non- disabling stroke;>60% by angiogram or >70% by ultrasound for asymptomatic ..
- PREDICTORS OF RECURRENT STROKE IN THE PROGRESS STUDYDuncan Campbell; Fiscal Year: 2003..controlled study of a perindopril-based blood pressure lowering regimen among individuals with stroke or transient ischemic attack within the previous 5 years. This project has two main aims: 1...
- WARFARIN VS ASPIRIN FOR INTRACRANIAL ARTERIAL STENOSISMarc Chimowitz; Fiscal Year: 2002..Conduct of Trial. Patients with transient ischemic attack (TIA) or stroke caused by angiographically proven stenosis (greater than or equal to 50 percent) of a ..
- RECURRENT STROKE--RISK FACTORS, CONTROL AND INTERACTIONMilton Alter; Fiscal Year: 1991..to be studied are diastolic and systolic blood pressure, diabetes, myocaridal infarction, arrhythmia and transient ischemic attack. Age and sex will be used as covariates...
- ENHANCED CAROTID BIFURCATION PHANTOM FOR MRI/AThomas Burke; Fiscal Year: 2000..carotid artery flow phantom for use in developing MRI applications to identify patients at risk for transient ischemic attack or strokes due to atherosclerotic carotid artery disease...
- ENHANCED CAROTID BIFURCATION PHANTOM FOR MRI/AThomas Burke; Fiscal Year: 2003..carotid artery flow phantom for use in developing MRI applications to identify patients at risk for transient ischemic attack or strokes. In Phase I, proof-of-concept was established...
- WOMENS ESTROGEN FOR STROKE TRIALRalph Horwitz; Fiscal Year: 2000..compared to placebo, reduces the risk of death or recurrent stroke in postmenopausal women with a transient ischemic attack or first non- disabling stroke...
- Novel Anti-Inflammatory To Treat AtherosclerosisPAUL BORRON; Fiscal Year: 2005..coronary artery disease (CAD), peripheral artery disease (PAD), heart attack, ischemic stroke, and transient ischemic attack (TIA), are the number one cause of mortality in the Western world and have a common underlying ..
- OPTIMIZING MANAGEMENT OF TRANSIENT ISCHEMIC ATTACKSS Johnston; Fiscal Year: 2005..This research will provide important results for clinicians and policy makers, and will foster the applicant's development as a health services researcher in cerebrovascular disease. ..
- CDP-choline: Mechanisms in Cerebral IschemiaRAO ADIBHATLA; Fiscal Year: 2006..Arachidonic acid activates neutral sphingomyelinase, resulting in membrane disintegration. PCCT activity was stimulated by exogenous CDP-choline. Aim 2 will be tested in gerbil transient forebrain ischemia. ..
- Diabetic Central and Peripheral Pro-InflammationMATTHEW HARTMAN; Fiscal Year: 2005..determine if type 2-like db/db mice have an enhanced IL-1-beta-mediated response to hypoxia, a model of transient ischemic attack, and examine the ability of anti inflammatory cytokines to modulate IL-1 beta- mediated central ..
- AMPHETAMINE ENHANCED STROKE RECOVERY--BURKE SRCI GROUPLarry Goldstein; Fiscal Year: 2002..However the treatment duration will be increased to a total of 10 sessions. ..
- MIDCAREER INVESTIGATOR AWARD IN CEREBROVASCULAR RESEARCHLarry Goldstein; Fiscal Year: 2004....
- Role of Egr-1 in post-stroke inflammation & brain damageRaghu Vemuganti; Fiscal Year: 2009..The ultimate goal is to define the role of EgM and its regulators to develop therapies to control cerebral inflammation at the level of transcription. ..
- Transcription Factors & Inflammatory Mediators in StrokeRaghu Vemuganti; Fiscal Year: 2007..The ultimate goal is to define the role of SOCS-3/STAT-3 in post-ischemic cerebral inflammation. ..
- Circle of Willis variability and migraineBRETT LEE CUCCHIARA; Fiscal Year: 2010..If this hypothesis is confirmed, this could lead to new treatments based on a better understanding of migraine mechanisms and might help identify patients with migraine who are at risk of stroke. ..
- PROGRESSION OF AORTIC ATHEROMA IN STROKE/TIA PATIENTSSouvik Sen; Fiscal Year: 2004..Designing of future placebo controlled prospective studies aimed at investigating measures that may be used to treat AA in stroke/TIA patients. ..
- Inflammation and Infection as Risk Factors in StrokeMitchell Elkind; Fiscal Year: 2006..Nationally recognized experts in stroke epidemiology and basic vascular biology will serve as mentors for these studies. ..
- PARAMEDIC FIELD INITIATION OF MAGNESIUM NEUROPROTECTIVEJeffrey Saver; Fiscal Year: 2003..abstract_text> ..
- GENE EXPRESSION-ENVIRONMENT LINK IN CEREBRAL ISCHEMIATERESITA BRIONES; Fiscal Year: 2006..Additionally, the sensory motor deficit seen following ischemic damage can affect the long-term outcome of these survivors. ..
- A THERAPEUTIC MODEL FOR CEREBRAL ISCHEMIATERESITA BRIONES; Fiscal Year: 2003..From a nursing perspective, results from this study are important clinically because the needs of most survivors of brain injury often times are for continuous nursing, while use of medical services may be intermittent. ..
- Inflammatory and Infectious Burden and Risk of StrokeMitchell Elkind; Fiscal Year: 2008..The cross-sectional associations between inflammatory and infectious markers and quantitative MRI abnormalities will also be assessed. ..
- Levels of Inflammatory Markers in Treatment of StrokeMitchell Elkind; Fiscal Year: 2008..abstract_text> ..
- BRAIN ISCHEMIA AND AORTIC ATHEROMATA IN A POPULATIONGEORGE PETTY; Fiscal Year: 2001..The investigators state that the study will also determine if clinical trials aimed at primary and secondary stroke prevention in these patients are warranted, and if so, assist in their design. ..
- EPIDEMIOLOGY OF ANTICOAGULATION IN ATRIAL FIBRILLATIONDaniel Singer; Fiscal Year: 2005..In all, continued study of our cohort will efficiently provide powerful insights into optimizing stroke prevention strategies for the many older Americans with AF. ..
- Vascular Protection in Acute Ischemic StrokeSusan Fagan; Fiscal Year: 2005..Collectively, the successful completion of the research summarized in this proposal can be expected to contribute to the development of methods to make reperfusion safer, and therefore more accessible, to human stroke patients. ..
- Familial Aggregation of StrokeDaniel Woo; Fiscal Year: 2005..Determining the component of the familial aggregation of ICH that is independent of the familial aggregation of environmental risk factors is a fundamental step in the analysis of the genetic epidemiology of stroke. ..
- Spousal communication and cancer prevention behaviorKELLY EVENSON; Fiscal Year: 2006..The long-term goal of this research is to develop better interventions which help prevent cancer, and other chronic health conditions, by involving spouses in preventive behavior change programs. [unreadable] [unreadable]..
- A Seven Tesla MRI System for Small Animals MRI/MRSRobert Knight; Fiscal Year: 2007..This Shared Instrumentation Grant will partially supply the funds to bring the present MRI/MRS system up to current standards, with HFHS supplying the rest. [unreadable] [unreadable] [unreadable]..
- New MRI techniques for cerebrovascular diseasesGregory Albers; Fiscal Year: 2008..This K24 research program will expand Dr. Albers' skills as a clinical investigator and allow him to become a more effective mentor. [unreadable] [unreadable]..
- NITROXIDERGIC CEREBROVASCULAR TONE DURING ANESTHESIAShailendra Joshi; Fiscal Year: 2005..abstract_text> ..
- Harvard Planning Grant for Institutional Clinical and Translational Science AwardDaniel Singer; Fiscal Year: 2006..We believe our planning process is specific, innovative yet disciplined, and should be robust. A full and competitive CTSA application will be produced in a timely manner. [unreadable] [unreadable] [unreadable]..
- NMR STUDIES OF HEMORRHAGIC TRANSFORMATION IN ISCHEMIARobert Knight; Fiscal Year: 2002....
- Neurochemical Challenge in Human Stroke RecoveryRONALD LAZAR; Fiscal Year: 2008..abstract_text> ..
- Diffusion weighted imaging Evaluation For Understanding Stroke Evolution2:DEFUSE Gregory W Albers; Fiscal Year: 2010..These findings will eventually lead to effective therapies for a large population of stroke patients who are currently ineligible for treatment and substantially reduce stroke-related disability. ..
- REACTIVE NITROGEN & CEREBRAL ISCHEMIC INJURYMUSH KHAN; Fiscal Year: 2003....
- CNS antigen sensitization in stroke.Kyra Becker; Fiscal Year: 2009..Data derived from this study will be used to plan future trials of immunomodulation in patients with stroke. ..
- EARLY DETERMINATION OF STROKE SUBTYPE: CT ANGIOGRAPHYScott Kasner; Fiscal Year: 2003..This approach will, for the first time, formally evaluate CTA as a tool for early stroke diagnosis and selection of patients with specific stroke mechanisms for specific mechanism-directed stroke therapies. ..
- Minocycline to Improve Neurologic Outcome (MINO Clinical Trial)David Hess; Fiscal Year: 2009..Since it is a safe drug and may also have activity against intracerebral hemorrhage, minocycline has excellent potential to become a "field drug", administered by ambulance crews and in rural hospitals. ..
- THE ROLE OF LYMPHOCYTES IN CEREBRAL ISCHEMIC INJURYKyra Becker; Fiscal Year: 2004....
- Understanding Change in Physical Activity PostpartumKELLY EVENSON; Fiscal Year: 2009..This proposal directly addresses the need to better understand multi-level factors involved in physical activity behavior change, RFA #CA-04-009 "Mechanisms of Physical Activity Behavior Change". ..
- MRI of Acute Vascular Injury and Hemorrhagic Transformation in Ischemic StrokeRobert A Knight; Fiscal Year: 2010..e., BBB opening) and both will be functions of the variations in BBB associated proteins and/or brain swelling;and 2) the size of these changes are correlated over time, ROI, and treatment. ..
- Protein Kinase B and C in Head InjuryLarry Jenkins; Fiscal Year: 2007....
- Stroke Hospitalization in the Elderly with Medicare FFSJudith Lichtman; Fiscal Year: 2009..These results will help inform decisions about the allocation of adequate resources, and more importantly, help identify opportunities to improve care and prevention of elderly stroke patients. ..