transient ischemic attack

Summary

Summary: Brief reversible episodes of focal, nonconvulsive ischemic dysfunction of the brain having a duration of less than 24 hours, and usually less than one hour, caused by transient thrombotic or embolic blood vessel occlusion or stenosis. Events may be classified by arterial distribution, temporal pattern, or etiology (e.g., embolic vs. thrombotic). (From Adams et al., Principles of Neurology, 6th ed, pp814-6)

Top Publications

  1. ncbi Get With the Guidelines-Stroke is associated with sustained improvement in care for patients hospitalized with acute stroke or transient ischemic attack
    Lee H Schwamm
    Massachusetts General Hospital, Boston, MA 02114, USA
    Circulation 119:107-15. 2009
  2. ncbi Transient ischemic attack--proposal for a new definition
    Gregory W Albers
    Stanford University School of Medicine Palo Alto, CA 94305, USA
    N Engl J Med 347:1713-6. 2002
  3. ncbi Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison
    Peter M Rothwell
    Stroke Prevention Research Unit, University Department of Clinical Neurology, Radcliffe Infirmary, Oxford, UK
    Lancet 370:1432-42. 2007
  4. ncbi High-dose atorvastatin after stroke or transient ischemic attack
    Pierre Amarenco
    Denis Diderot University, Paris
    N Engl J Med 355:549-59. 2006
  5. ncbi Usefulness of ambulatory 7-day ECG monitoring for the detection of atrial fibrillation and flutter after acute stroke and transient ischemic attack
    Denis Jabaudon
    Department of Neurology, University Hospital Geneva, Rue Micheli du Crest 24, 1211 Geneve 4, Switzerland Email
    Stroke 35:1647-51. 2004
  6. ncbi Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack
    S Claiborne Johnston
    Stroke Service, Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Lancet 369:283-92. 2007
  7. ncbi Predictive value of stroke and transient ischemic attack discharge diagnoses in The Danish National Registry of Patients
    Søren P Johnsen
    Department of Epidemiology and Social Medicine, Aarhus University, Vennelyst Boulevard 6, Aarhus C, Denmark
    J Clin Epidemiol 55:602-7. 2002
  8. ncbi Risk of stroke early after transient ischaemic attack: a systematic review and meta-analysis
    Matthew F Giles
    Stroke Prevention Research Unit, Oxford University Department of Clinical Neurology, Radcliffe Infirmary, Oxford, UK
    Lancet Neurol 6:1063-72. 2007
  9. pmc Ambient air pollution and risk for ischemic stroke and transient ischemic attack
    Lynda D Lisabeth
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109 2029, USA
    Ann Neurol 64:53-9. 2008
  10. ncbi Prevalence of abnormal glucose tolerance following a transient ischemic attack or ischemic stroke
    Walter N Kernan
    Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520 8025, USA
    Arch Intern Med 165:227-33. 2005

Detail Information

Publications281 found, 100 shown here

  1. ncbi Get With the Guidelines-Stroke is associated with sustained improvement in care for patients hospitalized with acute stroke or transient ischemic attack
    Lee H Schwamm
    Massachusetts General Hospital, Boston, MA 02114, USA
    Circulation 119:107-15. 2009
    Adherence to evidence-based guidelines for treatment of stroke or transient ischemic attack is suboptimal. We sought to establish whether participation in Get With the Guidelines-Stroke was associated with improvements in adherence.
  2. ncbi Transient ischemic attack--proposal for a new definition
    Gregory W Albers
    Stanford University School of Medicine Palo Alto, CA 94305, USA
    N Engl J Med 347:1713-6. 2002
  3. ncbi Effect of urgent treatment of transient ischaemic attack and minor stroke on early recurrent stroke (EXPRESS study): a prospective population-based sequential comparison
    Peter M Rothwell
    Stroke Prevention Research Unit, University Department of Clinical Neurology, Radcliffe Infirmary, Oxford, UK
    Lancet 370:1432-42. 2007
    ..Our aim was to determine the effect of more rapid treatment after TIA and minor stroke in patients who are not admitted direct to hospital...
  4. ncbi High-dose atorvastatin after stroke or transient ischemic attack
    Pierre Amarenco
    Denis Diderot University, Paris
    N Engl J Med 355:549-59. 2006
    Statins reduce the incidence of strokes among patients at increased risk for cardiovascular disease; whether they reduce the risk of stroke after a recent stroke or transient ischemic attack (TIA) remains to be established.
  5. ncbi Usefulness of ambulatory 7-day ECG monitoring for the detection of atrial fibrillation and flutter after acute stroke and transient ischemic attack
    Denis Jabaudon
    Department of Neurology, University Hospital Geneva, Rue Micheli du Crest 24, 1211 Geneve 4, Switzerland Email
    Stroke 35:1647-51. 2004
    ..study, we hypothesized that 7-day ambulatory ECG monitoring using an event-loop recording (ELR) device would detect otherwise occult episodes atrial fibrillation and flutter (AF) after acute stroke or transient ischemic attack (TIA).
  6. ncbi Validation and refinement of scores to predict very early stroke risk after transient ischaemic attack
    S Claiborne Johnston
    Stroke Service, Department of Neurology, University of California, San Francisco, CA 94143 0114, USA
    Lancet 369:283-92. 2007
    ....
  7. ncbi Predictive value of stroke and transient ischemic attack discharge diagnoses in The Danish National Registry of Patients
    Søren P Johnsen
    Department of Epidemiology and Social Medicine, Aarhus University, Vennelyst Boulevard 6, Aarhus C, Denmark
    J Clin Epidemiol 55:602-7. 2002
    We examined the predictive value of the discharge diagnoses of stroke and transient ischemic attack (TIA) in The National Registry of Patients (NRP) for participants in the Danish cohort study "Diet, Cancer, and Health...
  8. ncbi Risk of stroke early after transient ischaemic attack: a systematic review and meta-analysis
    Matthew F Giles
    Stroke Prevention Research Unit, Oxford University Department of Clinical Neurology, Radcliffe Infirmary, Oxford, UK
    Lancet Neurol 6:1063-72. 2007
    ..However, reliable estimation of this risk is necessary for planning effective service provision, clinical trials, and public education. We therefore did a systematic review of all studies of stroke risk early after TIA...
  9. pmc Ambient air pollution and risk for ischemic stroke and transient ischemic attack
    Lynda D Lisabeth
    Department of Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI 48109 2029, USA
    Ann Neurol 64:53-9. 2008
    ..The objective of this study was to investigate the association between short-term exposure to ambient air pollution and risk for ischemic cerebrovascular events in a US community...
  10. ncbi Prevalence of abnormal glucose tolerance following a transient ischemic attack or ischemic stroke
    Walter N Kernan
    Department of Internal Medicine, Yale School of Medicine, New Haven, CT 06520 8025, USA
    Arch Intern Med 165:227-33. 2005
    Despite current preventive therapies, patients with transient ischemic attack (TIA) and ischemic stroke remain at high risk for recurrent brain disease and cardiovascular events...
  11. ncbi Risk of stroke, transient ischemic attack, and vessel occlusion before endarterectomy in patients with symptomatic severe carotid stenosis
    Till Blaser
    Department of Neurology, University of Magdeburg, Magdeburg, Germany
    Stroke 33:1057-62. 2002
    ..We aimed to identify and determine the clinical relevance of parameters predictive of stroke recurrence and vessel occlusion before carotid endarterectomy...
  12. ncbi Time course of aquaporin expression after transient focal cerebral ischemia in mice
    Marlise de Castro Ribeiro
    Department of Neurology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
    J Neurosci Res 83:1231-40. 2006
    ..The expression of AQP1 remained unchanged. These results suggest that AQP4, but not AQP1 or AQP9, may play an important role in water movement associated with the pathophysiology of edema after transient cerebral ischemia in the mouse...
  13. ncbi Prediction of recurrent stroke and vascular death in patients with transient ischemic attack or nondisabling stroke: a prospective comparison of validated prognostic scores
    Christian Weimar
    Department of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122 Essen, Germany
    Stroke 41:487-93. 2010
    ..We aimed to prospectively compare the predictive accuracy of the Essen Stroke Risk Score, Stroke Prognostic Instrument, Hankey score, and the Life Long After Cerebral ischemia score...
  14. ncbi Fast assessment of stroke and transient ischaemic attack to prevent early recurrence (FASTER): a randomised controlled pilot trial
    James Kennedy
    Acute Stroke Programme, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, UK
    Lancet Neurol 6:961-9. 2007
    ..Patients with transient ischaemic attack (TIA) or minor stroke are at high immediate risk of stroke. The optimum early treatment options for these patients are not known...
  15. ncbi Fibrinogen concentration and risk of ischemic stroke and acute coronary events in 5113 patients with transient ischemic attack and minor ischemic stroke
    Peter M Rothwell
    Stroke Prevention Research Unit, University of Oxford, UK
    Stroke 35:2300-5. 2004
    ..Fibrinogen is an independent risk factor for coronary events in population-based studies and in patients with coronary heart disease, but there is uncertainty about prediction of stroke, particularly in secondary prevention...
  16. ncbi Microglial activation precedes and predominates over macrophage infiltration in transient focal cerebral ischemia: a study in green fluorescent protein transgenic bone marrow chimeric mice
    Matthias Schilling
    Department of Neurology, Universitatsklinikum Munster, Munster, Germany
    Exp Neurol 183:25-33. 2003
    ..GFP bone marrow chimeric mice are a powerful tool to further differentiate the function of resident microglia and hematogenous macrophages following cerebral ischemia...
  17. ncbi Reliability of clinical diagnosis of the symptomatic vascular territory in patients with recent transient ischemic attack or minor stroke
    Enrico Flossmann
    FRCP, Stroke Prevention Research Unit, University Department of Clinical Neurology, Level 6, West Wing, The John Radcliffe Hospital, Headington, Oxford OX3 9DU, UK
    Stroke 39:2457-60. 2008
    Knowledge of the vascular territory of a recent transient ischemic attack or minor stroke determines appropriate investigations and the need for territory-specific interventions such as endarterectomy and stenting...
  18. ncbi Carotid plaque inflammation is associated with cerebral microembolism in patients with recent transient ischemic attack or stroke: a pilot study
    Ramez Reda Moustafa
    Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
    Circ Cardiovasc Imaging 3:536-41. 2010
    ..We hypothesized that microembolic signals (MES) on transcranial Doppler will be associated with carotid plaque inflammation on (18)F fluorodeoxyglucose positron-emission tomography (FDG PET) in recently symptomatic patients...
  19. pmc Secondary prevention of stroke and transient ischemic attack: is more platelet inhibition the answer?
    James K Liao
    Cardiovascular Division, Department of Medicine, Brigham and Women s Hospital, 65 Landsdowne St, Rm 275, Cambridge, MA 02139, USA
    Circulation 115:1615-21. 2007
    ..200,000 of the 700,000 strokes reported annually in the United States, which makes secondary stroke prevention an important goal in the management of disease among patients who have experienced stroke or transient ischemic attack.
  20. ncbi Plasma concentration of C-reactive protein and risk of ischemic stroke and transient ischemic attack: the Framingham study
    N S Rost
    National Heart, Lung, and Blood Institute's Framingham Study, Framingham, Massachusetts, USA
    Stroke 32:2575-9. 2001
    ..We related plasma CRP levels to incidence of first ischemic stroke or transient ischemic attack (TIA) in the Framingham Study original cohort...
  21. ncbi Characteristics, performance measures, and in-hospital outcomes of the first one million stroke and transient ischemic attack admissions in get with the guidelines-stroke
    Gregg C Fonarow
    University of California, Los Angeles, USA
    Circ Cardiovasc Qual Outcomes 3:291-302. 2010
    ..this burden, Get With The Guideline (GWTG)-Stroke was developed to facilitate the measurement, tracking, and improvement in quality of care and outcomes for acute stroke and transient ischemic attack (TIA) patients in the United States.
  22. ncbi Clopidogrel plus aspirin versus aspirin alone for reducing embolisation in patients with acute symptomatic cerebral or carotid artery stenosis (CLAIR study): a randomised, open-label, blinded-endpoint trial
    Ka Sing Lawrence Wong
    Departments of Medicine and Therapeutics, Chinese University of Hong Kong, Hong Kong Special Administrative Region, China
    Lancet Neurol 9:489-97. 2010
    ..We aimed to investigate whether treatment with clopidogrel plus aspirin reduced the number of microembolic signals detected with transcranial doppler ultrasound compared with aspirin alone in patients with recent stroke...
  23. ncbi Hospital treatment of patients with ischemic stroke or transient ischemic attack using the "Get With The Guidelines" program
    Kenneth A Labresh
    MassPRO, Waltham, MA 02451, USA
    Arch Intern Med 168:411-7. 2008
    ..Adherence to evidence-based interventions for hospitalized patients who have experienced a stroke is suboptimal. We examined the association of process improvement and Internet-based data collection and decision support with stroke care...
  24. ncbi Chronic atrial fibrillation: Incidence, prevalence, and prediction of stroke using the Congestive heart failure, Hypertension, Age >75, Diabetes mellitus, and prior Stroke or transient ischemic attack (CHADS2) risk stratification scheme
    Stephan Rietbrock
    General Practice Research Database, Medicines and Health Care Products Regulatory Agency, London, United Kingdom
    Am Heart J 156:57-64. 2008
    ..The aim of the study is to estimate the incidence and prevalence of chronic AF (cAF) in the United Kingdom and test the accuracy of the CHADS2 score for stroke prediction...
  25. ncbi A population-based study of the prevalence of fatigue after transient ischemic attack and minor stroke
    Charlotte Winward
    Movement Science Group, Oxford Brookes University, Oxford, UK
    Stroke 40:757-61. 2009
    ....
  26. ncbi Medical (nonsurgical) intervention alone is now best for prevention of stroke associated with asymptomatic severe carotid stenosis: results of a systematic review and analysis
    Anne L Abbott
    Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
    Stroke 40:e573-83. 2009
    ....
  27. ncbi Risk of myocardial infarction and vascular death after transient ischemic attack and ischemic stroke: a systematic review and meta-analysis
    Emmanuel Touze
    Department of Neurology, Hopital Sainte Anne, Universite Paris Descartes, Faculte de Medecine, Paris Cedex 14
    Stroke 36:2748-55. 2005
    ..a systematic review and a meta-analysis to determine the risk of MI and nonstroke vascular death after transient ischemic attack (TIA) and ischemic stroke...
  28. ncbi A simple score (ABCD) to identify individuals at high early risk of stroke after transient ischaemic attack
    P M Rothwell
    Department of Clinical Neurology, University of Oxford, Radcliffe Infirmary, Oxford, OX2 6HE, UK
    Lancet 366:29-36. 2005
    ..Effective early management of patients with transient ischaemic attacks (TIA) is undermined by an inability to predict who is at highest early risk of stroke...
  29. ncbi Incidence and short-term prognosis of transient ischemic attack in a population-based study
    Dawn Kleindorfer
    Department of Emergency Medicine, University of Cincinnati, Ohio, USA
    Stroke 36:720-3. 2005
    ..We present the incidence and short-term prognosis of TIA within a large population with a significant proportion of minorities with out-of-hospital TIA...
  30. ncbi Early risk of stroke after transient ischemic attack: a systematic review and meta-analysis
    Caren M Wu
    Department of Medicine, University of Calgary, Calgary, AB, Canada
    Arch Intern Med 167:2417-22. 2007
    Recent observational studies suggest that the risk for stroke may be high in the first 90 days after transient ischemic attack (TIA). This finding may, however, not be consistent across existing studies assessing stroke risk after TIA...
  31. ncbi Serial MRI after transient focal cerebral ischemia in rats: dynamics of tissue injury, blood-brain barrier damage, and edema formation
    T Neumann-Haefelin
    Department of Radiology, Lucas MRS MRI Center, Stanford Stroke Center, Stanford University, CA, USA
    Stroke 31:1965-72; discussion 1972-3. 2000
    ....
  32. ncbi Timecourse of health-related quality of life as determined 3, 6 and 12 months after stroke. Relationship to neurological deficit, disability and depression
    Inga H Suenkeler
    Neurological Hospital, Hubertus Str 3 7, 35619 Braunfels, Germany
    J Neurol 249:1160-7. 2002
    ..Variables were identified that may predict poststroke life satisfaction...
  33. ncbi MRI findings may predict early neurologic deterioration in acute minor stroke or transient ischemic attack due to intracranial atherosclerosis
    Joon Tae Kim
    Department of Neurology, Chonnam National University Hospital, Gwangju, Republic of Korea
    Eur Neurol 64:95-100. 2010
    ..Although minor stroke and transient ischemic attack (TIA) seem benign, their occurrence in patients with ICAS may lead to early neurological deterioration (..
  34. ncbi Diffusion-weighted MRI in 300 patients presenting late with subacute transient ischemic attack or minor stroke
    Ursula G Schulz
    Stroke Prevention Research Unit, Department of Clinical Neurology, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
    Stroke 35:2459-65. 2004
    Many patients with transient ischemic attack (TIA) or minor stroke present to medical attention after a delay of several days or weeks, at which time it may be more difficult to obtain a clear history and clinical signs may have resolved...
  35. ncbi Is this patient having a stroke?
    Larry B Goldstein
    Department of Medicine, Duke Center for Cerebrovascular Disease, Durham, NC 27710, USA
    JAMA 293:2391-402. 2005
    Patients suspected of having a stroke or transient ischemic attack require accurate assessment for appropriate acute treatment and use of secondary preventive interventions.
  36. ncbi Agreement regarding diagnosis of transient ischemic attack fairly low among stroke-trained neurologists
    James Castle
    Department of Neurology, NorthShore University Healthsystem, Pritzker School of Medicine, Evanston, Ill, USA
    Stroke 41:1367-70. 2010
    Agreement between physicians to define the likelihood of a transient ischemic attack (TIA) remains poor...
  37. ncbi Prediction of major vascular events in patients with transient ischemic attack or ischemic stroke: a comparison of 7 models
    Annemarie D Wijnhoud
    Departments of Neurology, Erasmus Medical Center, Rotterdam, The Netherlands
    Stroke 41:2178-85. 2010
    ..In patients with a recent TIA or minor stroke, prediction of long-term risk of major vascular events is important, but difficult. We aimed to study the external validity of currently available prediction models...
  38. ncbi Crescendo transient Aura attacks: a transient ischemic attack mimic caused by focal subarachnoid hemorrhage
    Aaron Izenberg
    Dr Thomas and Harriet Black Acute TIA Unit and Regional Stroke Prevention Clinic, Division of Neurology and Brain Sciences Program, Sunnybrook Health Sciences Centre, Department of Medicine, University of Toronto, Toronto, Toronto, Ontario Canada
    Stroke 40:3725-9. 2009
    Diagnosis of transient ischemic attack can be difficult because many mimics exist. We report the clinical and neuroimaging features of a distinct hemorrhagic transient ischemic attack mimic.
  39. ncbi Joint effects of risk factors for stroke and transient ischemic attack in a German population: the EPIC Potsdam Study
    Cornelia Weikert
    Department of Epidemiology, German Institute of Human Nutrition, Potsdam Rehbruecke, Arthur Scheunert Allee 114 116, 14558, Nuthetal, Germany
    J Neurol 254:315-21. 2007
    ..The aim of the present study was to assess single and joint effects of risk factors on the incidence of stroke and TIA and to compare their magnitudes in a large population-based German cohort...
  40. ncbi Watershed infarcts in transient ischemic attack/minor stroke with > or = 50% carotid stenosis: hemodynamic or embolic?
    Ramez R Moustafa
    Stroke Research Group, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK
    Stroke 41:1410-6. 2010
    ..However, no study so far has directly addressed these conflicting scenarios...
  41. ncbi Blood test detecting autoantibodies to N-methyl-D-aspartate neuroreceptors for evaluation of patients with transient ischemic attack and stroke
    Svetlana A Dambinova
    Department of Neurology and Neurosurgery, I P Pavlov s State Medical University, 6 8 Tolstoj Str, St Petersburg, Russia 197102
    Clin Chem 49:1752-62. 2003
    ..investigated the diagnostic accuracy of serum aAbs to NR2A/2B, a subtype of NMDA receptors, in assessing transient ischemic attack (TIA) and ischemic stroke (IS) and its ability to distinguish cerebral ischemia from intracerebral ..
  42. ncbi High prevalence of stroke symptoms among persons without a diagnosis of stroke or transient ischemic attack in a general population: the REasons for Geographic And Racial Differences in Stroke (REGARDS) study
    Virginia J Howard
    Department of Epidemiology, University of Alabama at Birmingham School of Public Health, 1665 University Blvd, Birmingham, AL 35294 0022, USA
    Arch Intern Med 166:1952-8. 2006
    ..This study assessed the prevalence of stroke symptoms in a stroke- and transient ischemic attack (TIA)-free population and the association of symptoms with risk factors indexed by the Framingham Stroke ..
  43. ncbi Headache at stroke onset in 2196 patients with ischemic stroke or transient ischemic attack
    Susanne Tentschert
    University Clinic of Neurology, Clinical Department of Clinical Neurology, University of Vienna, Austria
    Stroke 36:e1-3. 2005
    ..Headache is a common symptom in acute ischemic and hemorrhagic stroke, but many aspects of its association with other clinical factors are controversial...
  44. ncbi Strong independent correlation of proteinuria with cerebral microbleeds in patients with stroke and transient ischemic attack
    Bruce Ovbiagele
    Department ofNeurology, StrokeCenter, University ofCalifornia, Los Angeles, CA 90095, USA
    Arch Neurol 67:45-50. 2010
    ..To assess the association of proteinuria with the frequency and number of cerebral microbleeds (CMB), a harbinger of future hemorrhagic stroke...
  45. ncbi Midazolam challenge reinduces neurological deficits after transient ischemic attack
    Ronald M Lazar
    From the Columbia University College of Physicians and Surgeons, Columbia Presbyterian Medical Center, New York, NY, USA
    Stroke 34:794-6. 2003
    A transient ischemic attack (TIA) in the brain is classically considered a syndrome lasting <24 hours...
  46. ncbi Temporary middle cerebral artery occlusion in the rat: consistent protocol for a model of stroke and reperfusion
    B S Aspey
    Reta Lila Weston Institute of Neurological Studies, UCL Medical School, London, UK
    Neuropathol Appl Neurobiol 26:232-42. 2000
    ....
  47. ncbi Clinical and radiological features of childhood cerebral infarction following varicella zoster virus infection
    Elena Miravet
    Neurology Department, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Dev Med Child Neurol 49:417-22. 2007
    ..A more comprehensive diagnostic evaluation should be considered in children with AIS who do not fit the clinical and radiological profile outlined, even where there is a history of recent VZV infection...
  48. ncbi Systematic review and pooled analysis of published and unpublished validations of the ABCD and ABCD2 transient ischemic attack risk scores
    Matthew F Giles
    Stroke Prevention Research Unit, NIHR Biomedical Research Centre, Oxford University Department of Clinical Neurology, John Radcliffe Hospital, Oxford, UK
    Stroke 41:667-73. 2010
    The ABCD system was derived to predict early risk of stroke after transient ischemic attack. Independent validations have reported conflicting results...
  49. ncbi Prognosis in patients with transient ischaemic attack (TIA) and minor stroke attending TIA services in the North West of England: the NORTHSTAR Study
    J R Selvarajah
    Department of Neurology, Leeds General Infirmary, Leeds, UK
    J Neurol Neurosurg Psychiatry 79:38-43. 2008
    ..We investigated prognosis, and the use of the ABCD2 score, in patients attending TIA services in the North West of England with a diagnosis of TIA or minor stroke...
  50. ncbi Chickenpox and stroke in childhood: a study of frequency and causation
    R Askalan
    Hospital for Sick Children and the University of Toronto, Toronto, Canada
    Stroke 32:1257-62. 2001
    ..Varicella-associated AIS has characteristic features, including a 2-fold increase in recurrent AIS and transient ischemic attacks. Varicella is an important risk factor for childhood AIS...
  51. ncbi Recurrent events in transient ischemic attack and minor stroke: what events are happening and to which patients?
    Shelagh B Coutts
    Department of Clinical Neurosciences, Room C1246, Foothills Medical Centre, 1403 29th St SW, Calgary, AB, T2N 2T9, Canada
    Stroke 39:2461-6. 2008
    The risk of a recurrent stroke after transient ischemic attack (TIA) or minor stroke is high. Clinical trials are needed to assess acute treatment options in these patients...
  52. ncbi Detection of diffusion-weighted MRI abnormalities in patients with transient ischemic attack: correlation with clinical characteristics
    Ralph A Crisostomo
    Stanford Medical School, Palo Alto, CA, USA
    Stroke 34:932-7. 2003
    ..We assessed the utility of DWI in patients with transient ischemic attack (TIA) to further evaluate the usefulness of this technique in these individuals.
  53. ncbi Yield of systematic transcranial Doppler in patients with transient ischemic attack
    Elena Meseguer
    INSERM U698 and Denis Diderot University and Medical School, Paris, France
    Ann Neurol 68:9-17. 2010
    Urgent evaluation and treatment of transient ischemic attack (TIA) patients in a dedicated TIA clinic may reduce the 90-day stroke risk by 80%...
  54. ncbi Retrospective study of total healthcare costs associated with chronic nonvalvular atrial fibrillation and the occurrence of a first transient ischemic attack, stroke or major bleed
    Stephen J Boccuzzi
    IMS Health, Plymouth Meeting, PA, USA
    Curr Med Res Opin 25:2853-64. 2009
    ..To determine the direct healthcare costs associated with the onset of chronic nonvalvular atrial fibrillation (CNVAF), warfarin utilization and the occurrence of cerebrovascular events in a commercially-insured population...
  55. ncbi Transient ischemic attack and stroke can be differentiated by analyzing early diffusion-weighted imaging signal intensity changes
    Kerstin Winbeck
    Department of Neurology, Technical University of Munich, Möhlstr 28, 81675 Munich, Germany
    Stroke 35:1095-9. 2004
    ..Signal intensity changes occur not only in patients with definite stroke but also in up to 67% of transient ischemic attack (TIA) patients...
  56. ncbi Triaging transient ischemic attack and minor stroke patients using acute magnetic resonance imaging
    Shelagh B Coutts
    Seaman Family MR Research Centre, Foothills Medical Centre, Calgary Health Region, Calgary, Alberta, Canada
    Ann Neurol 57:848-54. 2005
    ..imaging (DWI) lesions and vessel occlusion on acute brain magnetic resonance images of minor stroke and transient ischemic attack patients predicted the occurrence of subsequent stroke and functional outcome...
  57. ncbi Is the ABCD score useful for risk stratification of patients with acute transient ischemic attack?
    Brett L Cucchiara
    Department of Neurology, University of Pennsylvania Medical Center, Philadelphia, PA 19104, USA
    Stroke 37:1710-4. 2006
    A 6-point scoring system (ABCD) was described recently for stratifying risk after transient ischemic attack (TIA). This score incorporates age (A), blood pressure (B), clinical features (C), and duration (D) of TIA...
  58. ncbi Population-based study of ABCD2 score, carotid stenosis, and atrial fibrillation for early stroke prediction after transient ischemic attack: the North Dublin TIA study
    Orla C Sheehan
    Neurovascular Clinical Science Unit, Mater University Hospital University College Dublin, Ireland
    Stroke 41:844-50. 2010
    b>Transient ischemic attack (TIA) etiologic data and the ABCD(2) score may improve early stroke risk prediction, but studies are required in population-based cohorts...
  59. ncbi Pioglitazone improves insulin sensitivity among nondiabetic patients with a recent transient ischemic attack or ischemic stroke
    Walter N Kernan
    Department of Medicine, Yale University School of Medicine, PO Box 208025, New Haven, CT 06520 8025, USA
    Stroke 34:1431-6. 2003
    ..the effectiveness of pioglitazone compared with placebo for improving insulin sensitivity among nondiabetic patients with a recent transient ischemic attack (TIA) or nondisabling ischemic stroke and impaired insulin sensitivity.
  60. ncbi Inherited prothrombotic risk factors in children with stroke, transient ischemic attack, or migraine
    Désirée Coen Herak
    Clinical Institute of Laboratory Diagnosis, Clinical Hospital Center Zagreb, Zagreb University School of Medicine, Kispaticeva 12, Zagreb 10000, Croatia
    Pediatrics 123:e653-60. 2009
    The aim of this study was to investigate the prevalence and possible association of inherited prothrombotic risk factors in children with stroke, transient ischemic attack, or migraine.
  61. ncbi When to expect negative diffusion-weighted images in stroke and transient ischemic attack
    P N Sylaja
    Calgary Stroke Program, Department of Clinical Neurosciences, Foothills Medical Centre, Room 1162, University of Calgary, Alberta, Canada
    Stroke 39:1898-900. 2008
    ..The frequency of DWI negative cerebral ischemia and clinical factors associated with such a circumstance is not well understood...
  62. ncbi Recurrent cerebrovascular events associated with patent foramen ovale, atrial septal aneurysm, or both
    J L Mas
    Department of Neurology, Sainte Anne Hospital, Paris V University, Paris, France
    N Engl J Med 345:1740-6. 2001
    ..We studied the risks of recurrent cerebrovascular events associated with these cardiac abnormalities...
  63. ncbi Diagnostic usefulness of the ABCD2 score to distinguish transient ischemic attack and minor ischemic stroke from noncerebrovascular events: the North Dublin TIA Study
    Orla C Sheehan
    Neurovascular Clinical Science Unit, Mater University Hospital, University College Dublin, Dublin, Ireland
    Stroke 40:3449-54. 2009
    b>Transient ischemic attack (TIA) diagnosis is frequently difficult in clinical practice. Noncerebrovascular symptoms are often misclassified as TIA by nonspecialist physicians...
  64. ncbi Inadequate acoustical temporal bone window in patients with a transient ischemic attack or minor stroke: role of skull thickness and bone density
    Annemarie D Wijnhoud
    Department of Neurology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
    Ultrasound Med Biol 34:923-9. 2008
    ..may provide important diagnostic and prognostic information in patients with ischemic stroke or transient ischemic attack. TCD also enhances the effect of thrombolytic treatment in patients with acute stroke...
  65. ncbi Accuracy of paramedic identification of stroke and transient ischemic attack in the field
    W S Smith
    Department of Neurology, University of California, San Francisco 94143 0114, USA
    Prehosp Emerg Care 2:170-5. 1998
    ..To determine the accuracy of acute stroke identification by paramedics in an urban emergency medical services system...
  66. ncbi Persistent hyperfibrinogenemia in acute ischemic stroke / transient ischemic attack (TIA)
    Shani Shenhar-Tsarfaty
    Department of Neurology, Tel Aviv Sourasky Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
    Thromb Haemost 99:169-73. 2008
    ..Prompt and long-term, rather than short term, interventions to reduce the concentrations of this protein might therefore be of relevance...
  67. ncbi Very early risk of stroke after a first transient ischemic attack
    J K Lovett
    Stroke Prevention Research Unit, Department of Clinical Neurology, Radcliffe Infirmary, Woodstock Rd, Oxford OX2 6HE UK
    Stroke 34:e138-40. 2003
    The commonly quoted early risks of stroke after a first transient ischemic attack (TIA)-1% to 2% at 7 days and 2% to 4% at 1 month-are likely to be underestimates because of the delay before inclusion into previous studies and the ..
  68. ncbi Effects of an individualized multimedia computer program for health education in patients with a recent minor stroke or transient ischemic attack - a randomized controlled trial
    E Maasland
    Department of Neurology, Erasmus MC University Medical Center, Rotterdam, The Netherlands
    Acta Neurol Scand 115:41-8. 2007
    b>Transient ischemic attack (TIA) and stroke patients often show a striking lack of knowledge about their disease...
  69. ncbi Long-term mortality and risk of stroke after transient ischemic attack: a hospital-based cohort study
    Christian Weimar
    Dept of Neurology, University of Duisburg Essen, Hufelandstr 55, 45122, Essen, Germany
    J Neurol 256:639-44. 2009
    Stroke and mortality rates in patients with transient ischemic attack (TIA) differ widely between community-based studies and research cohorts...
  70. ncbi Diagnosis and initial management of stroke and transient ischemic attack across UK health regions from 1992 to 1996: experience of a national primary care database
    R G Gibbs
    Department of Vascular Surgery, Imperial College School of Medicine, Charing Cross Campus, London, UK
    Stroke 32:1085-90. 2001
    ..burden of cerebrovascular disease across the different health regions of the United Kingdom and to determine whether the initial management of new cases of stroke and transient ischemic attack (TIA) was uniform across the United Kingdom:
  71. ncbi Increased risk of stroke and transient ischemic attack in 5-year survivors of Hodgkin lymphoma
    Marie L De Bruin
    Department of Epidemiology, The Netherlands Cancer Institute, Amsterdam, The Netherlands
    J Natl Cancer Inst 101:928-37. 2009
    Information on clinically verified stroke and transient ischemic attack (TIA) following Hodgkin lymphoma is scarce...
  72. ncbi Relation between the metabolic syndrome and ischemic stroke or transient ischemic attack: a prospective cohort study in patients with atherosclerotic cardiovascular disease
    N Koren-Morag
    Division of Epidemiology, Sackler Medical Faculty, Tel Aviv University, Israel
    Stroke 36:1366-71. 2005
    ..We explored the relation of metabolic syndrome versus frank diabetes with first-ever ischemic stroke or transient ischemic attack (TIA) in a large cohort of patients with atherosclerotic cardiovascular disease.
  73. ncbi Medium-term variability of blood pressure and potential underdiagnosis of hypertension in patients with previous transient ischemic attack or minor stroke
    Robert L Cuffe
    Stroke Prevention Research Unit, Department of Clinical Neurology, University of Oxford, Oxford, England
    Stroke 37:2776-83. 2006
    ..The extent of medium-term variability in BP is most marked in patients with a previous transient ischemic attack (TIA) or stroke...
  74. ncbi Clinical inquiries. Is an outpatient workup safe for patients with a transient ischemic attack?
    Melissa Franklin
    Moses Cone Family Practice Residency, Greensboro, NC, USA
    J Fam Pract 53:567-9. 2004
  75. ncbi Current management of transient ischemic attack
    Padmavathy N Sylaja
    Calgary Stroke Program, Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta, Canada
    Am J Cardiovasc Drugs 7:67-74. 2007
    b>Transient ischemic attack (TIA) is a precursor to ischemic stroke. At least half of patients with TIA have a new, small ischemic lesion demonstrable on magnetic resonance imaging using a diffusion weighted sequence...
  76. ncbi Patients with transient ischemic attack or minor stroke should be admitted to hospital: for
    Geoffrey A Donnan
    Department of Clinical Neuroscience, University of Calgary, Calgary, Alberta, Canada
    Stroke 37:1137-8. 2006
  77. ncbi Morphology of the patent foramen ovale in asymptomatic versus symptomatic (stroke or transient ischemic attack) patients
    Sachin S Goel
    Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, Ohio, USA
    Am J Cardiol 103:124-9. 2009
    ..differences in the anatomy of PFOs on TEE in patients with and without recurrent cryptogenic stroke or transient ischemic attack. The results of TEE in 58 patients who had PFO closure for cryptogenic cerebrovascular accident (CVA) ..
  78. ncbi Transient ischemic attack patients with fluctuations are at highest risk for early stroke
    Anastasios Chatzikonstantinou
    Department of Neurology, Universitatsklinikum Mannheim, Ruprecht Karls Universitat Heidelberg, Mannheim, Germany
    Cerebrovasc Dis 27:594-8. 2009
    ..The management and risk of early stroke are unclear in patients with fluctuating neurological symptoms. We aimed to evaluate the clinical course of these patients presenting within 24 h after onset of acute cerebral ischemia symptoms...
  79. ncbi Sleep apnea in patients with transient ischemic attack and minor stroke: opportunity for risk reduction of recurrent stroke?
    Wesley Chan
    Calgary Stroke Program, Faculty of Medicine, University of Calgary, Alberta, Canada
    Stroke 41:2973-5. 2010
    ..Obstructive sleep apnea (OSA) may increase this risk. The objectives of our study were to determine the prevalence and severity of OSA and its clinical presentation in this population...
  80. ncbi Survey of blood pressure control status in patients with ischemic stroke or transient ischemic attack in China
    Yilong Wang
    Department of Neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China
    Neurol Res 30:348-55. 2008
    We sought to assess the current status of blood pressure control and the use of antihypertensive drugs in patients with ischemic stroke (IS) or transient ischemic attack (TIA) in China.
  81. ncbi Low vitamin B6 but not homocyst(e)ine is associated with increased risk of stroke and transient ischemic attack in the era of folic acid grain fortification
    Peter J Kelly
    Stroke Service, Department of Neurology, VBK 802, Massachusetts General Hospital, Fruit St, Boston, MA 02114, USA
    Stroke 34:e51-4. 2003
    ..We performed a case-control study to determine the risk of stroke and transient ischemic attack (TIA) associated with tHcy and low vitamin status in a postfortification US sample.
  82. ncbi The association of transient ischemic attack symptoms with memory impairment among elderly participants of the Third US National Health and Nutrition Examination Survey
    Paul Y Takahashi
    Department of Internal Medicine, Division of Primary Care Internal Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Geriatr Psychiatry Neurol 22:46-51. 2009
    ..Stroke is a well-known risk factor for vascular dementia. However, the association of transient ischemic attacks with cognitive impairment is less well-established...
  83. ncbi Identification of culprit lesions after transient ischemic attack by combined 18F fluorodeoxyglucose positron-emission tomography and high-resolution magnetic resonance imaging
    John R Davies
    Division of Cardiovascular Medicine, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
    Stroke 36:2642-7. 2005
    ..In this study, plaque inflammation was quantified before endarterectomy using the combination of 18F fluorodeoxyglucose positron (FDG)-emission tomography (PET) and high-resolution MRI (HRMRI)...
  84. ncbi Limb shaking transient ischemic attack--an unusual presentation of carotid occlusive disease. A case report and review of the literature
    A B M Salah Uddin
    Seton Hall University School of Graduate Medical Education, South Orange, NJ 07079, USA
    Parkinsonism Relat Disord 10:451-3. 2004
    Limb shaking transient ischemic attack (TIA) is an uncommon presentation of carotid occlusive disease. This unusual form of TIA is not well recognized and may be mistaken for focal epilepsy, delaying proper diagnosis and treatment...
  85. ncbi Frequency and determinants of lipid testing in ischemic stroke and transient ischemic attack: findings from get with the guidelines-stroke
    Eric E Smith
    Calgary Stroke Program, University of Calgary, Alberta, Canada
    Stroke 41:232-8. 2010
    National guidelines recommend lipid testing for all patients with ischemic stroke and transient ischemic attack. This study examined the frequency and predictors for in-hospital low-density lipoprotein testing using data from a ..
  86. ncbi Symptom progression or fluctuation in transient ischemic attack patients predicts subsequent stroke
    Makoto Nakajima
    Cerebrovascular Division, Department of Medicine, National Cardiovascular Center, Suita, Japan
    Cerebrovasc Dis 29:221-7. 2010
    The aim of this study was to investigate whether progression or fluctuation of transient ischemic attack (TIA) symptoms is a predictor of subsequent stroke.
  87. ncbi Optimal dosing of intravenous unfractionated heparin bolus in transient ischemic attack or stroke
    Kyusik Kang
    Department of Neurology, Eulji General Hospital, Seoul, corrected Republic of Korea
    Clin Appl Thromb Hemost 16:126-31. 2010
    ..partial thromboplastin time over the first 6-hour period in a cohort of 54 patients admitted with transient ischemic attack or stroke...
  88. ncbi Implementation of an emergency department based transient ischemic attack clinical pathway: a pilot study in knowledge translation
    Michael D Brown
    Grand Rapids MERC Michigan State University Program in Emergency Medicine, Grand Rapids, MI, USA
    Acad Emerg Med 14:1114-9. 2007
    To assess the feasibility of implementing an emergency department (ED)-based transient ischemic attack (TIA) clinical pathway that uses computer-based clinical support, and to evaluate measures of quality, safety, and efficiency.
  89. ncbi Perindopril-based blood pressure-lowering reduces major vascular events in patients with atrial fibrillation and prior stroke or transient ischemic attack
    Hisatomi Arima
    George Institute for International Health, University of Sydney, Australia
    Stroke 36:2164-9. 2005
    ..The primary objective here is to determine whether routine blood pressure-lowering provides additional protection for this high-risk patient group...
  90. ncbi Transient ischemic attack reported with paroxetine use
    Gail H Manos
    Department of Psychiatry, Naval Medical Center Portsmouth, Portsmouth, VA 23708 2197, USA
    Ann Pharmacother 38:617-20. 2004
    To report the occurrence of a transient ischemic attack (TIA) temporally related to the initiation of paroxetine.
  91. ncbi Ischemic preconditioning is mediated by erythropoietin through PI-3 kinase signaling in an animal model of transient ischemic attack
    Samit Malhotra
    Department of Neurology, Albert Einstein College of Medicine, Bronx, New York, USA
    J Neurosci Res 83:19-27. 2006
    ..By using a middle cerebral artery occlusion (MCAo) model of transient ischemic attack (TIA), we sought to determine whether EPO is required for IP in the protective response against focal ..
  92. ncbi Transient ischemic attack: definition and natural history
    Louis R Caplan
    Cerebrovascular Disease Service, Palmer 127, West Campus, Beth Israel Deaconess Medical Center, 330 Brookline Avenue, Boston, MA 02215, USA
    Curr Atheroscler Rep 8:276-80. 2006
    The standard definition of a transient ischemic attack--"a cerebral dysfunction of an ischemic nature lasting no longer than 24 hours with a tendency to recur"--was arrived at arbitrarily and is no longer tenable...
  93. pmc Prognostic value of the ABCD2 score beyond short-term follow-up after transient ischemic attack (TIA)--a cohort study
    Katrin Holzer
    Department of Neurology, Klinikum rechts der Isar, Technische Universitat, Munich, Germany
    BMC Neurol 10:50. 2010
    b>Transient ischemic attack (TIA) patients are at a high vascular risk. Recently the ABCD2 score was validated for evaluating short-term stroke risk after TIA...
  94. ncbi Early stroke risk after transient ischemic attack among individuals with symptomatic intracranial artery stenosis
    Bruce Ovbiagele
    Stroke Center and Department of Neurology, UCLA Medical Center, University of California at Los Angeles, 710 Westwood Plaza, Los Angeles, CA 90095, USA
    Arch Neurol 65:733-7. 2008
    Little is known about short-term vascular risk after transient ischemic attack (TIA) caused by intracranial atherosclerosis.
  95. ncbi Patients enrolled in large randomized clinical trials of antiplatelet treatment for prevention after transient ischemic attack or ischemic stroke are not representative of patients in clinical practice: the Netherlands Stroke Survey
    Lisette Maasland
    Van Weel Bethesda Hospital, Department of Neurology, Stationsweg 22, 3247 BW Dirksland, The Netherlands
    Stroke 40:2662-8. 2009
    ..use of antiplatelet drugs in reducing the risk of new vascular events in patients with a recent transient ischemic attack or ischemic stroke...
  96. ncbi Early stroke risk after a transient ischemic attack: can it be minimized?
    Jonathan Y Streifler
    Stroke 39:1655-6. 2008
  97. ncbi Cerebral microhemorrhages predict new disabling or fatal strokes in patients with acute ischemic stroke or transient ischemic attack
    Jean Martin Boulanger
    Clinique Neuro Rive Sud, 4896 Blvd Taschereau 250, Greenfield Park, Provinvr of Quebec, Canada, J4V 2J2
    Stroke 37:911-4. 2006
    ..Cerebral microhemorrhages (MHs) are common among patients presenting with acute ischemic stroke and may predict both subsequent ischemic and hemorrhagic strokes...
  98. ncbi ABCD2 score predicts severity rather than risk of early recurrent events after transient ischemic attack
    Arvind Chandratheva
    Stroke Prevention Research Unit, Oxford University Department of Clinical Neurology, John Radcliffe Hospital, Oxford, England
    Stroke 41:851-6. 2010
    The ABCD(2) score predicts the early risk of stroke after transient ischemic attack (TIA). However, data on the severity of recurrent events would also be useful...
  99. ncbi The incidence of sleep apnea in patients with stroke or transient ischemic attack
    A Wierzbicka
    Department of Clinical Neurophysiology, Institute of Psychiatry and Neurology, Warsaw, Poland
    J Physiol Pharmacol 57:385-90. 2006
    ..The present study evaluated the frequency of SDB in patients with stroke or transient ischemic attack transient ischemic attack. We studied 43 patients (mean age 68.5 +/-11...
  100. ncbi Intra-arterial thrombin injection of an ascending aortic pseudoaneurysm complicated by transient ischemic attack and rescued with systemic abciximab
    P H Lin
    Division of Vascular Surgery, Department of Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA
    J Vasc Surg 34:939-42. 2001
    ..However, the procedure was complicated by a sudden transient ischemic attack caused by thrombus propagation into the cerebral circulation...
  101. ncbi Hemodynamic and metabolic changes in transient ischemic attack patients: a magnetic resonance angiography and (1)H-magnetic resonance spectroscopy study performed within 3 days of onset of a transient ischemic attack
    Robertus H C Bisschops
    Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands
    Stroke 33:110-5. 2002
    We investigated whether patients with transient ischemic attack (TIA) have systemic low flow to the brain or an abnormal intracranial flow distribution caused by an abnormal anatomy of the circle of Willis...

Research Grants64

  1. Cerebrovascular Disease and its Consequences in the Strong Study Cohort
    Dedra S Buchwald; Fiscal Year: 2013
    ..white matter hyperintensities, infarcts, and hemorrhages, in populations without known stroke or transient ischemic attack. Further, overt CBVD, such as stroke, was strikingly less common than covert MRI-defined brain disease...
  2. Insulin Resistance Intervention after Stroke (IRIS) Trial
    Walter N Kernan; Fiscal Year: 2013
    Among millions of persons worldwide who survive an ischemic stroke or transient ischemic attack (TIA) each year, a major source of morbidity and mortality is recurrent stroke and myocardial infarction...
  3. APOPTOSIS OF SMOOTH MUSCLE CELLS IN CAROTID PLAQUES
    Devendra K Agrawal; Fiscal Year: 2013
    ..RELEVANCE: Many patients with blockade of their neck artery develop neurological symptoms including transient ischemic attack or stroke. This is primarily due to breaking off the atherosclerotic plaque in the neck artery...
  4. Sleep Apnea in TIA: Reducing Cardiovascular Risk with Positive Airway Pressure
    Henry Klar Yaggi; Fiscal Year: 2012
    ..Patients with transient ischemic attack (TIA) have a high prevalence of sleep apnea (60-80%), and they are at high risk within 1 year for ..
  5. Blood Transfusions: Gender Differences in Utilization, Predictors, and Outcomes
    Mary A M Rogers; Fiscal Year: 2010
    ..regarding blood transfusion, infection, and thrombotic events (deep-vein thrombosis, pulmonary embolism, transient ischemic attack, stroke, and myocardial infarction) will be extracted from CMS files...
  6. Predictive optimal anticlotting treatment for segmented patient populations
    Peter J Tonellato; Fiscal Year: 2013
    ..S. with over 140,000 deaths annually. The majority of stroke incidences are due to ischemia (87%) or transient ischemic attack (TIA, ~5-10%) and are typically managed by the use of anticlotting drugs including anticoagulants (e.g...
  7. Targeted management intervention for African-American men with TIA or stroke
    MARTHA X SAJATOVIC; Fiscal Year: 2013
    ..Interventions targeted to those AA men who have had transient ischemic attack (TIA) or a milder first-time stroke (FTS) may be particularly well-timed as some individuals experience ..
  8. Klotho and the pathogenesis of cardiovascular disease
    Richard D Semba; Fiscal Year: 2013
    ..disease (myocardial infarction, angina, stroke, congestive heart failure, peripheral artery disease, transient ischemic attack), carotid intima-media thickness, brachial flow-mediated dilation, cardiovascular events and mortality ..
  9. Atrial Fibrillation Precursors May Be Novel Stroke Risk Factors
    Hooman Kamel; Fiscal Year: 2013
    ..diagnoses of paroxysmal supraventricular tachycardia are associated with the risk of stroke after transient ischemic attack. This aim will be pursued using a validated ICD-9-CM code for paroxysmal supraventricular tachycardia ..
  10. Cardiovascular Health Study - Transition Phase - Renewal
    Richard A Kronmal; Fiscal Year: 2009
    ..new CVD events (including incident myocardial infarction, angina, congestive heart failure, stroke, transient ischemic attack, peripheral arterial disease, and death)...
  11. Cardiovascular Health Study - Transition Phase - Renewal
    Richard A Kronmal; Fiscal Year: 2011
    ..new CVD events (including incident myocardial infarction, angina, congestive heart failure, stroke, transient ischemic attack, peripheral arterial disease, and death)...
  12. Cardiovascular Health Study - Transition Phase - Renewal
    Richard A Kronmal; Fiscal Year: 2010
    ..new CVD events (including incident myocardial infarction, angina, congestive heart failure, stroke, transient ischemic attack, peripheral arterial disease, and death)...
  13. Asymptomatic Carotid Stenosis: Cognitive Function and Plaque Correlates
    Brajesh K Lal; Fiscal Year: 2013
    ..who are currently labeled as "asymptomatic" in the absence of a focal neurologic deficit (stroke, transient ischemic attack)...
  14. UK NETT Clinical Site Hub
    ROGER LOYD HUMPHRIES; Fiscal Year: 2013
    ..placebo in acute ischemic stroke), POINT (clopidogrel loading for stroke prevention after transient ischemic attack), and ProTECT (progesterone v. placebo in traumatic brain injury)...
  15. Role for MicroRNAs in Ischemic Tolerance
    Julie Anne Saugstad; Fiscal Year: 2012
    ..Clinical evidence suggests that endogenous preconditioning triggered by a transient ischemic attack is present in the human brain...
  16. Impact of Bariatric Surgery on Long-term Diabetes Remission and Complications
    DAVID ERIC ARTERBURN; Fiscal Year: 2013
    ..i) cardiac ischemia, infarction, angioplasty/stent, or coronary bypass surgery;(ii) stroke or transient ischemic attack and (iii) peripheral vascular disease-related ulceration, revascularization or amputation This study ..
  17. Vertebrobasilar Flow Evaluation and Risk of Transient Ischemic Attack and Stroke
    Sepideh Amin-Hanjani; Fiscal Year: 2012
    ..abstract_text> ..
  18. Digital Assistant Supported Medication Adherence and Medical Monitoring Syst
    ANTHONY STERNS; Fiscal Year: 2009
    ..Eligible ischemic stroke and transient ischemic attack (TIA) patients undergoing acute treatment at a regional hospital will be approached for consent and then ..
  19. Developing a Rational Clinical Approach to the Disposition of TIA Cases in the ED
    Mathew Reeves; Fiscal Year: 2009
    DESCRIPTION (provided by applicant): Transient Ischemic Attack (TIA) or mini-stroke is an episode of acute focal neurological symptoms that lasts less than 24 hours...
  20. Neuronal Injury and Blood Genomics
    Frank Sharp; Fiscal Year: 2005
    ..proposal will determine whether short durations of global cerebral ischemia, focal cerebral ischemia (transient ischemic attack), hypoglycemia and seizures produce different white blood cell genomic responses in rats that can be ..
  21. Carotid Revascularization Endarterectomy vs Stenting Trial
    Thomas G Brott; Fiscal Year: 2010
    ..carotid artery (>50% by angiogram or >70% by ultrasound for symptomatic disease in patients with transient ischemic attack or ipsilateral non- disabling stroke;>60% by angiogram or >70% by ultrasound for asymptomatic ..
  22. PREDICTORS OF RECURRENT STROKE IN THE PROGRESS STUDY
    Duncan Campbell; Fiscal Year: 2003
    ..controlled study of a perindopril-based blood pressure lowering regimen among individuals with stroke or transient ischemic attack within the previous 5 years. This project has two main aims: 1...
  23. WARFARIN VS ASPIRIN FOR INTRACRANIAL ARTERIAL STENOSIS
    Marc Chimowitz; Fiscal Year: 2002
    ..Conduct of Trial. Patients with transient ischemic attack (TIA) or stroke caused by angiographically proven stenosis (greater than or equal to 50 percent) of a ..
  24. RECURRENT STROKE--RISK FACTORS, CONTROL AND INTERACTION
    Milton Alter; Fiscal Year: 1991
    ..to be studied are diastolic and systolic blood pressure, diabetes, myocaridal infarction, arrhythmia and transient ischemic attack. Age and sex will be used as covariates...
  25. ENHANCED CAROTID BIFURCATION PHANTOM FOR MRI/A
    Thomas Burke; Fiscal Year: 2000
    ..carotid artery flow phantom for use in developing MRI applications to identify patients at risk for transient ischemic attack or strokes due to atherosclerotic carotid artery disease...
  26. ENHANCED CAROTID BIFURCATION PHANTOM FOR MRI/A
    Thomas Burke; Fiscal Year: 2003
    ..carotid artery flow phantom for use in developing MRI applications to identify patients at risk for transient ischemic attack or strokes. In Phase I, proof-of-concept was established...
  27. WOMENS ESTROGEN FOR STROKE TRIAL
    Ralph Horwitz; Fiscal Year: 2000
    ..compared to placebo, reduces the risk of death or recurrent stroke in postmenopausal women with a transient ischemic attack or first non- disabling stroke...
  28. Novel Anti-Inflammatory To Treat Atherosclerosis
    PAUL BORRON; Fiscal Year: 2005
    ..coronary artery disease (CAD), peripheral artery disease (PAD), heart attack, ischemic stroke, and transient ischemic attack (TIA), are the number one cause of mortality in the Western world and have a common underlying ..
  29. OPTIMIZING MANAGEMENT OF TRANSIENT ISCHEMIC ATTACKS
    S Johnston; Fiscal Year: 2005
    ..This research will provide important results for clinicians and policy makers, and will foster the applicant's development as a health services researcher in cerebrovascular disease. ..
  30. CDP-choline: Mechanisms in Cerebral Ischemia
    RAO ADIBHATLA; Fiscal Year: 2006
    ..Arachidonic acid activates neutral sphingomyelinase, resulting in membrane disintegration. PCCT activity was stimulated by exogenous CDP-choline. Aim 2 will be tested in gerbil transient forebrain ischemia. ..
  31. Diabetic Central and Peripheral Pro-Inflammation
    MATTHEW HARTMAN; Fiscal Year: 2005
    ..determine if type 2-like db/db mice have an enhanced IL-1-beta-mediated response to hypoxia, a model of transient ischemic attack, and examine the ability of anti inflammatory cytokines to modulate IL-1 beta- mediated central ..
  32. AMPHETAMINE ENHANCED STROKE RECOVERY--BURKE SRCI GROUP
    Larry Goldstein; Fiscal Year: 2002
    ..However the treatment duration will be increased to a total of 10 sessions. ..
  33. MIDCAREER INVESTIGATOR AWARD IN CEREBROVASCULAR RESEARCH
    Larry Goldstein; Fiscal Year: 2004
    ....
  34. Role of Egr-1 in post-stroke inflammation & brain damage
    Raghu Vemuganti; Fiscal Year: 2009
    ..The ultimate goal is to define the role of EgM and its regulators to develop therapies to control cerebral inflammation at the level of transcription. ..
  35. Transcription Factors & Inflammatory Mediators in Stroke
    Raghu Vemuganti; Fiscal Year: 2007
    ..The ultimate goal is to define the role of SOCS-3/STAT-3 in post-ischemic cerebral inflammation. ..
  36. Circle of Willis variability and migraine
    BRETT LEE CUCCHIARA; Fiscal Year: 2010
    ..If this hypothesis is confirmed, this could lead to new treatments based on a better understanding of migraine mechanisms and might help identify patients with migraine who are at risk of stroke. ..
  37. PROGRESSION OF AORTIC ATHEROMA IN STROKE/TIA PATIENTS
    Souvik Sen; Fiscal Year: 2004
    ..Designing of future placebo controlled prospective studies aimed at investigating measures that may be used to treat AA in stroke/TIA patients. ..
  38. Inflammation and Infection as Risk Factors in Stroke
    Mitchell Elkind; Fiscal Year: 2006
    ..Nationally recognized experts in stroke epidemiology and basic vascular biology will serve as mentors for these studies. ..
  39. PARAMEDIC FIELD INITIATION OF MAGNESIUM NEUROPROTECTIVE
    Jeffrey Saver; Fiscal Year: 2003
    ..abstract_text> ..
  40. GENE EXPRESSION-ENVIRONMENT LINK IN CEREBRAL ISCHEMIA
    TERESITA BRIONES; Fiscal Year: 2006
    ..Additionally, the sensory motor deficit seen following ischemic damage can affect the long-term outcome of these survivors. ..
  41. A THERAPEUTIC MODEL FOR CEREBRAL ISCHEMIA
    TERESITA BRIONES; Fiscal Year: 2003
    ..From a nursing perspective, results from this study are important clinically because the needs of most survivors of brain injury often times are for continuous nursing, while use of medical services may be intermittent. ..
  42. Inflammatory and Infectious Burden and Risk of Stroke
    Mitchell Elkind; Fiscal Year: 2008
    ..The cross-sectional associations between inflammatory and infectious markers and quantitative MRI abnormalities will also be assessed. ..
  43. Levels of Inflammatory Markers in Treatment of Stroke
    Mitchell Elkind; Fiscal Year: 2008
    ..abstract_text> ..
  44. BRAIN ISCHEMIA AND AORTIC ATHEROMATA IN A POPULATION
    GEORGE PETTY; Fiscal Year: 2001
    ..The investigators state that the study will also determine if clinical trials aimed at primary and secondary stroke prevention in these patients are warranted, and if so, assist in their design. ..
  45. EPIDEMIOLOGY OF ANTICOAGULATION IN ATRIAL FIBRILLATION
    Daniel Singer; Fiscal Year: 2005
    ..In all, continued study of our cohort will efficiently provide powerful insights into optimizing stroke prevention strategies for the many older Americans with AF. ..
  46. Vascular Protection in Acute Ischemic Stroke
    Susan Fagan; Fiscal Year: 2005
    ..Collectively, the successful completion of the research summarized in this proposal can be expected to contribute to the development of methods to make reperfusion safer, and therefore more accessible, to human stroke patients. ..
  47. Familial Aggregation of Stroke
    Daniel Woo; Fiscal Year: 2005
    ..Determining the component of the familial aggregation of ICH that is independent of the familial aggregation of environmental risk factors is a fundamental step in the analysis of the genetic epidemiology of stroke. ..
  48. Spousal communication and cancer prevention behavior
    KELLY EVENSON; Fiscal Year: 2006
    ..The long-term goal of this research is to develop better interventions which help prevent cancer, and other chronic health conditions, by involving spouses in preventive behavior change programs. [unreadable] [unreadable]..
  49. A Seven Tesla MRI System for Small Animals MRI/MRS
    Robert Knight; Fiscal Year: 2007
    ..This Shared Instrumentation Grant will partially supply the funds to bring the present MRI/MRS system up to current standards, with HFHS supplying the rest. [unreadable] [unreadable] [unreadable]..
  50. New MRI techniques for cerebrovascular diseases
    Gregory Albers; Fiscal Year: 2008
    ..This K24 research program will expand Dr. Albers' skills as a clinical investigator and allow him to become a more effective mentor. [unreadable] [unreadable]..
  51. NITROXIDERGIC CEREBROVASCULAR TONE DURING ANESTHESIA
    Shailendra Joshi; Fiscal Year: 2005
    ..abstract_text> ..
  52. Harvard Planning Grant for Institutional Clinical and Translational Science Award
    Daniel Singer; Fiscal Year: 2006
    ..We believe our planning process is specific, innovative yet disciplined, and should be robust. A full and competitive CTSA application will be produced in a timely manner. [unreadable] [unreadable] [unreadable]..
  53. NMR STUDIES OF HEMORRHAGIC TRANSFORMATION IN ISCHEMIA
    Robert Knight; Fiscal Year: 2002
    ....
  54. Neurochemical Challenge in Human Stroke Recovery
    RONALD LAZAR; Fiscal Year: 2008
    ..abstract_text> ..
  55. Diffusion weighted imaging Evaluation For Understanding Stroke Evolution2:DEFUSE
    Gregory W Albers; Fiscal Year: 2010
    ..These findings will eventually lead to effective therapies for a large population of stroke patients who are currently ineligible for treatment and substantially reduce stroke-related disability. ..
  56. REACTIVE NITROGEN & CEREBRAL ISCHEMIC INJURY
    MUSH KHAN; Fiscal Year: 2003
    ....
  57. CNS antigen sensitization in stroke.
    Kyra Becker; Fiscal Year: 2009
    ..Data derived from this study will be used to plan future trials of immunomodulation in patients with stroke. ..
  58. EARLY DETERMINATION OF STROKE SUBTYPE: CT ANGIOGRAPHY
    Scott Kasner; Fiscal Year: 2003
    ..This approach will, for the first time, formally evaluate CTA as a tool for early stroke diagnosis and selection of patients with specific stroke mechanisms for specific mechanism-directed stroke therapies. ..
  59. Minocycline to Improve Neurologic Outcome (MINO Clinical Trial)
    David Hess; Fiscal Year: 2009
    ..Since it is a safe drug and may also have activity against intracerebral hemorrhage, minocycline has excellent potential to become a "field drug", administered by ambulance crews and in rural hospitals. ..
  60. THE ROLE OF LYMPHOCYTES IN CEREBRAL ISCHEMIC INJURY
    Kyra Becker; Fiscal Year: 2004
    ....
  61. Understanding Change in Physical Activity Postpartum
    KELLY EVENSON; Fiscal Year: 2009
    ..This proposal directly addresses the need to better understand multi-level factors involved in physical activity behavior change, RFA #CA-04-009 "Mechanisms of Physical Activity Behavior Change". ..
  62. MRI of Acute Vascular Injury and Hemorrhagic Transformation in Ischemic Stroke
    Robert A Knight; Fiscal Year: 2010
    ..e., BBB opening) and both will be functions of the variations in BBB associated proteins and/or brain swelling;and 2) the size of these changes are correlated over time, ROI, and treatment. ..
  63. Protein Kinase B and C in Head Injury
    Larry Jenkins; Fiscal Year: 2007
    ....
  64. Stroke Hospitalization in the Elderly with Medicare FFS
    Judith Lichtman; Fiscal Year: 2009
    ..These results will help inform decisions about the allocation of adequate resources, and more importantly, help identify opportunities to improve care and prevention of elderly stroke patients. ..