- Fibroblast growth factor-23 (FGF-23) is independently correlated to aortic calcification in haemodialysis patients
Mohamed M Nasrallah
Department of Nephrology, School of Medicine, Kasr El Aini School of Medicine, Cairo University, Cairo, Egypt
Nephrol Dial Transplant 25:2679-85. 2010
..We conducted this study to investigate the relationship between FGF-23 and aortic calcification in a standard haemodialysis setting...
- Thoracic aortic calcification and coronary heart disease events: the multi-ethnic study of atherosclerosis (MESA)
Matthew J Budoff
Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA, United States
Atherosclerosis 215:196-202. 2011
..Few studies have evaluated interactions or independent incremental risk for coronary and thoracic aortic calcification (TAC). The independent predictive value of TAC for CHD events is not well-established...
- Failure to prevent progressive dilation of ascending aorta by aortic valve replacement in patients with bicuspid aortic valve: comparison with tricuspid aortic valve
Department of Cardiology, National Cardiovascular Center, 5 7 1 Fujishiro dai, Suita, Osaka 565 8565, Japan
Circulation 108:II291-4. 2003
..Patients with bicuspid aortic valve (BAV) have been frequently complicated with ascending aortic dilation possibly because of hemodynamic burdens by aortic stenosis (AS) or regurgitation (AR) or congenital fragility of the aortic wall...
- Vitamin D receptor activators can protect against vascular calcification
Department of Pediatrics, Washington University School of Medicine, St Louis, Missouri 63110, USA
J Am Soc Nephrol 19:1509-19. 2008
..We conclude that low, clinically relevant dosages of calcitriol and paricalcitol may protect against CKD-stimulated vascular calcification...
- Vascular matrix remodeling in patients with bicuspid aortic valve malformations: implications for aortic dilatation
Paul W M Fedak
Division of Cardiac Surgery, University of Toronto and Toronto General Hospital, 200 Elizabeth Street, Toronto, Ontario, Canada M5G 2C4
J Thorac Cardiovasc Surg 126:797-806. 2003
..In bicuspid aortic valve disease a deficiency of fibrillin-1 and increased matrix metalloproteinase matrix degradation might result in aortic degeneration and dilatation...
- Thoracic aorta calcification detected by electron beam tomography predicts all-cause mortality
Raul D Santos
Lipid Clinic Heart Institute InCor, University of Sao Paulo Medical School Hospital, Sao Paulo, Brazil
Atherosclerosis 209:131-5. 2010
..However, the predictive value of thoracic aorta calcification (TAC), which can be additionally identified without further scanning during assessment of CAC, is unknown...
- Single gene disorders of the aortic wall
Marc K Halushka
Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
Cardiovasc Pathol 21:240-4. 2012
..The aim is to briefly describe the historical record and physical manifestations and then focus on cardiovascular complications, the causative genes, and current research into these entities...
- Comparing coronary artery calcium and thoracic aorta calcium for prediction of all-cause mortality and cardiovascular events on low-dose non-gated computed tomography in a high-risk population of heavy smokers
Peter C Jacobs
Julius Center for Health Sciences and Primary Care, Department of Radiology, University Medical Center Utrecht, Netherlands
Atherosclerosis 209:455-62. 2010
..This study compared CAC and TAC as independent predictors of all-cause mortality and cardiovascular events in a population of heavy smokers using low-dose, non-gated CT...
- Relationship between coronary artery and descending thoracic aortic calcification as detected by computed tomography: the Multi-Ethnic Study of Atherosclerosis
Division of Cardiology, Los Angeles Biomedical Research Institute at Harbor UCLA, Torrance, CA 90502, USA
Atherosclerosis 204:440-6. 2009
..Previous studies demonstrate that DTAC is associated with obstructive CAD and coronary risk factors. However, no prior studies have examined the association of CAC and DTAC as detected by cardiac CT in a large population-based cohort...
- Aortic arch plaques and risk of recurrent stroke and death
Marco R Di Tullio
Division of Cardiology, Department of Medicine, Columbia University, College of Physicians and Surgeons, 630 W 168th St, New York, NY 10032, USA
Circulation 119:2376-82. 2009
..Aortic arch plaques are a risk factor for ischemic stroke. Although the stroke mechanism is conceivably thromboembolic, no randomized studies have evaluated the efficacy of antithrombotic therapies in preventing recurrent events...
- Identification of pathways for atherosclerosis in mice: integration of quantitative trait locus analysis and global gene expression data
Susanna S Wang
Department of Human Genetics, University of California at Los Angeles, Los Angeles, CA 90095 1679, USA
Circ Res 101:e11-30. 2007
..Thus, global gene expression in peripheral tissues can reflect the systemic perturbations that contribute to atherosclerosis...
- Short-term delivery of anti-PlGF antibody delays progression of atherosclerotic plaques to vulnerable lesions
Vesalius Research Center, VIB, KULeuven, Campus Gasthuisberg, Herestraat 49, Box 912, 3000 Leuven, Belgium
Cardiovasc Res 86:29-36. 2010
..Previous gene-inactivation studies revealed that the loss of PlGF delays atherosclerotic lesion development and inhibits macrophage infiltration, but the activity of an anti-PlGF antibody (alphaPlGF mAb) has not been evaluated yet...
- Differential effects of vitamin D receptor activators on vascular calcification in uremic rats
Renal Division, Washington University School of Medicine, St Louis, Missouri 63110, USA
Kidney Int 72:709-15. 2007
..Hence, different VDRAs have different effects on vascular calcification in uremic rats. The effects are independent of the serum calcium-phosphate product suggesting independent mechanisms...
- Hypercholesterolemia stimulates angiotensin peptide synthesis and contributes to atherosclerosis through the AT1A receptor
Division of Cardiovascular Medicine, Wethington Building, Room 521, University of Kentucky, Lexington, KY 40536 0200, USA
Circulation 110:3849-57. 2004
..We hypothesized that hypercholesterolemia stimulates the production of angiotensin peptides to provide a rationale for the profound effect of AT1A receptor deficiency on atherogenesis...
- Oral administration of an active form of vitamin D3 (calcitriol) decreases atherosclerosis in mice by inducing regulatory T cells and immature dendritic cells with tolerogenic functions
Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
Arterioscler Thromb Vasc Biol 30:2495-503. 2010
..To determine whether the administration of an active form of vitamin D(3) (calcitriol) could prevent atherosclerosis through anti-inflammatory actions...
- Predictors of ascending aortic dilatation with bicuspid aortic valve: a wide spectrum of disease expression
Alessandro Della Corte
Department of Cardiothoracic and Respiratory Sciences, Second University of Naples, V Monaldi Hospital, Via L Bianchi, 80131 Naples, Italy
Eur J Cardiothorac Surg 31:397-404; discussion 404-5. 2007
..This study aimed to describe the features and identify the predictors of ascending aorta dilatation in patients with congenital bicuspid aortic valve (BAV)...
- Aortic calcification in haemodialysis patients with diabetes mellitus
Inoue Hospital, Department of Nephrology, Osaka City University Graduate School of Medicine, 1 4 3, Asahi machi, Abeno Ku, Osaka 545 8585, Japan
Nephrol Dial Transplant 20:2472-8. 2005
..This study examined the risk factors of aortic calcification in a large number of haemodialysis patients, and compared risk factors between diabetic and non-diabetic patients...
- Aldosterone administration to mice stimulates macrophage NADPH oxidase and increases atherosclerosis development: a possible role for angiotensin-converting enzyme and the receptors for angiotensin II and aldosterone
Lipid Research Laboratory, Technion Faculty of Medicine, the Rappaport Family Institute for Research in Medical Sciences and Rambam Medical Center, Haifa, Israel
Circulation 109:2213-20. 2004
..We questioned the effect and mechanisms of action of administration of aldosterone to apolipoprotein E-deficient (E(0)) mice on their macrophages and aorta oxidative status and the ability of pharmacological agents to block this effect...
- Coronary artery, aortic wall, and valvular calcification in nondialyzed individuals with type 2 diabetes and renal disease
Division of Nephrology and Hypertension, Department of Pediatrics, Harbor UCLA Medical Center and Research and Education Institute, Torrance, California 90502, USA
Kidney Int 64:263-71. 2003
..We undertook this study to test the hypothesis that vascular and valvular calcification begins and is often severe long before diabetic renal disease progresses to ESRD...
- Aortoesophageal fistula after thoracic aortic stent-graft placement: a rare but catastrophic complication of a novel emerging technique
Department of Cardiology, West German Heart Center Essen, Essen, Germany
JACC Cardiovasc Interv 2:570-6. 2009
..Our goal was to report characteristics and outcomes of 6 patients with aortoesophageal fistula (AEF) after thoracic endovascular aortic repair (TEVAR)...
- Effect of aortic taper on patterns of blood flow and wall shear stress in rabbits: association with age
Department of Aeronautics, Imperial College London, South Kensington Campus, United Kingdom
Atherosclerosis 223:114-21. 2012
..The distribution of atherosclerotic lesions changes with age in human and rabbit aortas. We investigated if this can be explained by changes in patterns of blood flow and wall shear stress...
- The impact of epiaortic ultrasonographic scanning on the risk of perioperative stroke
Division of Cardiac Surgery, Ospedali Riuniti, Strada di Fiume 447, 34100 Trieste, Italy
Eur J Cardiothorac Surg 29:720-8. 2006
..To assess the impact of epiaortic scanning on the incidence of perioperative stroke in patients undergoing cardiac surgery...
- Calcification of the aortic arch: risk factors and association with coronary heart disease, stroke, and peripheral vascular disease
Division of Research, Kaiser Permanente Medical Care Program, 3505 Broadway, Oakland, CA 94611
JAMA 283:2810-5. 2000
..However, the incremental predictive value of vascular calcification, beyond traditional coronary risk factors, is not clearly established...
- Spatiotemporal patterns of smooth muscle cell changes in ascending aortic dilatation with bicuspid and tricuspid aortic valve stenosis: focus on cell-matrix signaling
Alessandro Della Corte
Department of Cardiothoracic and Respiratory Sciences, Second University of Naples, V Monaldi Hospital, Naples, Italy
J Thorac Cardiovasc Surg 135:8-18, 18.e1-2. 2008
..The present study examined temporal and spatial patterns of extracellular matrix and smooth muscle cell changes in the ascending aorta with bicuspid and tricuspid aortic valve stenosis...
- Progression of coronary artery calcification and thoracic aorta calcification in kidney transplant recipients
Division of Nephrology, Cliniques Universitaires Saint Luc, Université Catholique de Louvain Medical School, Brussels, Belgium
Am J Kidney Dis 59:258-69. 2012
..Longitudinal studies of vascular calcification in KTRs are few and small and have short follow-up. We assessed the evolution of coronary artery (CAC) and thoracic aorta calcification and their determinants in a cohort of prevalent KTRs...
- Risk factors of the progression of abdominal aortic calcification in patients on chronic haemodialysis
First Department of Internal Medicine, Miyazaki Medical College, University of Miyazaki, Kihara 5200, Kiyotake, Miyazaki 889 1692, and Koga General Hospital, Japan
Nephrol Dial Transplant 22:2032-7. 2007
..It is not known whether acute changes of the serum calcium concentration before and after HD (DeltaCa) are associated with the development of aortic calcification...
- Efficacy of intraoperative epiaortic ultrasound scanning for preventing stroke after coronary artery bypass surgery
Department of Cardiovascular Surgery, Saitama Medical Center, Jichi Medical University, Saitama, Japan
Ann Thorac Cardiovasc Surg 15:98-104. 2009
..The aim of this study was to clarify the efficacy of intraoperative epiaortic ultrasound scanning (EAS) for preventing cerebral emboli following coronary artery bypass grafting (CABG)...
- Increased aortic pulse wave velocity is associated with silent cerebral small-vessel disease in hypertensive patients
Léon H G Henskens
Division of General Internal Medicine, Maastricht University Medical Centre, and Cardiovascular Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
Hypertension 52:1120-6. 2008
..In conclusion, aortic stiffness is independently associated with manifestations of cerebral small-vessel disease in hypertensive patients, linking systemic large- to cerebral small-artery disease...
- Population-based study of the relationship between atherosclerotic aortic debris and cerebrovascular ischemic events
George W Petty
Division of Cerebrovascular Diseases, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Mayo Clin Proc 81:609-14. 2006
..To assess the validity of the suggestion that protruding atheromatous material in the thoracic aorta is an important cause of cerebrovascular ischemic events (CIEs) (ie, transient ischemic attack or ischemic stroke)...
- Dissociation of aortic pulse wave velocity with risk factors for cardiovascular disease other than hypertension: a systematic review
King s College London British Heart Foundation Centre, Cardiovascular Division, Department of Clinical Pharmacology, St Thomas Hospital, London, United Kingdom
Hypertension 54:1328-36. 2009
..The prognostic value of cfPWV may relate to a process of arterial ageing unrelated to classic risk factors other than hypertension...
- Atherosclerosis, vascular remodeling, and impairment of endothelium-dependent relaxation in genetically altered hyperlipidemic mice
Department of Internal Medicine, University of Iowa College of Medicine, Iowa City 52242 1081, USA
Arterioscler Thromb Vasc Biol 17:2333-40. 1997
..We speculate that other factors, such as the absence of LDL receptors, may contribute to the differences in the extent of atherosclerosis in these two models of hyperlipidemia...
- Retrograde embolism from the descending aorta: visualization by multidirectional 3D velocity mapping in cryptogenic stroke
Department of Neurology and Clinical Neurophysiology, University Hospital Freiburg, Freiburg, Germany
Stroke 40:1505-8. 2009
..The purpose of this study was to determine the role of plaques >or=4 mm and thrombi (complex plaques) in the descending aorta (DAo) as an embolic high-risk source for stroke...
- Echocardiography in aortic diseases: EAE recommendations for clinical practice
Servei de Cardiologia, Hospital Vall d Hebron, P degrees Vall d Hebron 119, 08035 Barcelona, Spain
Eur J Echocardiogr 11:645-58. 2010
Echocardiography plays an important role in the diagnosis and follow-up of aortic diseases. Evaluation of the aorta is a routine part of the standard echocardiographic examination...
- Thoracic aortic calcium versus coronary artery calcium for the prediction of coronary heart disease and cardiovascular disease events
Nathan D Wong
Division of Cardiology, University of California, Irvine, California, USA
JACC Cardiovasc Imaging 2:319-26. 2009
..This study compared the ability of coronary artery calcium (CAC) and thoracic aortic calcium (TAC) to predict coronary heart disease (CHD) and cardiovascular disease (CVD) events...
- Aortic dilatation and dissection in Turner syndrome
Lea Ann Matura
Developmental Endocrinology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA
Circulation 116:1663-70. 2007
..It is unknown whether aortic dilatation precedes acute aortic dissection in TS and, if so, what specific diameter predicts impending deterioration...
- Utility of left subclavian artery revascularization in association with endoluminal repair of acute and chronic thoracic aortic pathology
Brian G Peterson
Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA
J Vasc Surg 43:433-9. 2006
..Various methods have been used to address this issue. We report our experience with subclavian artery revascularization in association with endoluminal repair of acute and chronic thoracic aortic pathology...
- Inhibition of diet-induced atherosclerosis and endothelial dysfunction in apolipoprotein E/angiotensin II type 1A receptor double-knockout mice
Klinik fur Innere Medizin III, Universitatsklinikum des Saarlandes, Homburg Saar, Germany
Circulation 110:3062-7. 2004
..Angiotensin II type 1 (AT1) receptor activation is potentially involved in the multifactorial pathogenesis of atherosclerosis...
- The effects of sevelamer and calcium acetate on proxies of atherosclerotic and arteriosclerotic vascular disease in hemodialysis patients
Glenn M Chertow
Division of Nephrology, Moffitt Long Hospitals and UCSF Mt Zion Medical Center, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
Am J Nephrol 23:307-14. 2003
..Whether the specific calcium preparation (acetate vs. carbonate) might influence the likelihood of progressive calcification was debated...
- Association of aortic atherosclerosis with cerebral beta-amyloidosis and learning deficits in a mouse model of Alzheimer's disease
Departments of Medicine, Pharmacology, and Genetics, University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
Am J Pathol 163:2155-64. 2003
..Our results suggest that synergistic mechanisms may be involved in the pathogenesis of atherosclerosis and AD. These findings may have important implications in the prevention and treatment of cardiovascular diseases as well as AD...
- Relation of aortic wall thickness and distensibility to cardiovascular risk factors (from the Multi-Ethnic Study of Atherosclerosis [MESA])
Ashkan A Malayeri
Department of Radiology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
Am J Cardiol 102:491-6. 2008
..Decreased AD was further associated with current smoking, African American ethnicity, and higher high-density lipoprotein cholesterol level...
- Atherosclerosis of the aorta: risk factor, risk marker, or innocent bystander? A prospective population-based transesophageal echocardiography study
Department of Neurology, Mayo Clinic, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 44:1018-24. 2004
..The goal of this study was to investigate whether complex aortic atherosclerosis is associated with increased risk of vascular events in a non-selected population...
- Cardiovascular magnetic resonance parameters of atherosclerotic plaque burden improve discrimination of prior major adverse cardiovascular events
Imaging Science Laboratories Translational and Molecular Imaging Institute, Department of Radiology, Mount Sinai School of Medicine, New York, NY, USA
J Cardiovasc Magn Reson 11:10. 2009
..The purpose of this study was to determine if patients with traditional risk factors and prior MACE had increased cardiovascular magnetic resonance (CMR) plaque burden measures compared to patients with risk factors but no prior events...
- Quantitative assay for mouse atherosclerosis in the aortic root
Department of Cell Biology, The Cleveland Clinic Foundation, OH, USA
Methods Mol Med 129:83-95. 2006
..Here, we provide the detailed methods for the quantitative analysis of mouse aortic root lesion area...
- Chondrocyte rather than osteoblast conversion of vascular cells underlies medial calcification in uremic rats
Department of Pathophysiology, University of Antwerp, Wilrijk, Belgium
Arterioscler Thromb Vasc Biol 30:1741-50. 2010
..To investigate cell biological changes in calcified aortas of rats that experienced chronic renal failure...
- Studies of the human aortic intima by a direct quantitative assay of mutant alleles in the mitochondrial genome
Institute of General Pathology and Pathophysiology RAMS, Moscow, Russia
Atherosclerosis 204:184-90. 2009
- Aortic dilatation in patients with bicuspid aortic valve
Presidio Monospecialistico di Alta Specializzazione G M Lancisi, Ospedali Riuniti Umberto I G M Lancisi G Salesi, Ancona, Italy
J Cardiovasc Med (Hagerstown) 7:11-20. 2006
..However, the optimal timing of aortic surgery in BAV patients remains uncertain because of the limited data available on the natural history of asymptomatic aortic dilatation...
- Aortoesophageal fistula secondary to stent-graft repair of the thoracic aorta
Department of Cardiology, West German Heart Center, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
J Endovasc Ther 11:161-7. 2004
..To report the incidence and management of aortoesophageal fistula (AEF) secondary to endovascular stent-graft repair of the descending thoracic aorta...
- The serum level of bone-specific alkaline phosphatase activity is associated with aortic calcification in osteoporosis patients
Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, South 1, West 16, Chuo Ku, Sapporo, Japan
J Bone Miner Metab 22:594-6. 2004
..Bone-specific alkaline phosphatase is the most important marker for osteoblast differentiation; furthermore, the serum level of its activity may reflect the process of calcification of the aorta in osteoporosis patients...
- Different patterns of extracellular matrix protein expression in the convexity and the concavity of the dilated aorta with bicuspid aortic valve: preliminary results
Department of Cardiothoracic and Respiratory Sciences, Second University of Naples, Italy
J Thorac Cardiovasc Surg 130:504-11. 2005
..This study aimed to assess extracellular matrix protein expression patterns at the convexity (right anterolateral wall) and the concavity of the dilated ascending aorta in patients with bicuspid aortic valve disease...
- Aortic constriction exacerbates atherosclerosis and induces cardiac dysfunction in mice lacking apolipoprotein E
Jiao Hui Wu
Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill 27599 7525, USA
Arterioscler Thromb Vasc Biol 22:469-75. 2002
..Our study also suggests that apolipoprotein E plays an important role in modulating cardiac hypertrophy...
- Statin-induced cholesterol lowering and plaque regression after 6 months of magnetic resonance imaging-monitored therapy
Joao A C Lima
Cardiology Division of the Department of Medicine, Johns Hopkins University, Baltimore, MD, USA
Circulation 110:2336-41. 2004
..We hypothesized that statin-induced AP regression can be monitored by MRI and detected earlier than previously reported and is significantly associated with its lipid-lowering effect...
- Aortic allograft vasculopathy is mediated by CD8(+) T cells in Cyclosporin A immunosuppressed mice
Ellen L Vessie
Department of Microbiology and Immunology, Dalhousie University, Halifax, Nova Scotia, Canada B3H 1X5
Transpl Immunol 15:35-44. 2005
..The in vitro data suggest that the indirect pathway remains intact in this population of CyA resistant CD8(+) T cells...
- The influence of mechanical properties on wall stress and distensibility of the dilated ascending aorta
Ruth J Okamoto
Department of Mechanical Engineering, Washington University, Campus Box 1185, One Brookings Drive, St Louis, MO 63130 4899, USA
J Thorac Cardiovasc Surg 126:842-50. 2003
..We sought to determine how intrinsic mechanical properties of dilated ascending aorta influence in vivo distensibility and wall stress, potential contributing factors to the risk of aortic rupture and dissection...
- Surgical management of primary aortoesophageal fistula secondary to thoracic aneurysm
M J Reardon
Department of Surgery, Baylor College of Medicine, The Methodist Hospital, Houston, Texas 77030, USA
Ann Thorac Surg 69:967-70. 2000
..We report a successful repair of primary aortoesophageal fistula, secondary to descending thoracic aortic aneurysm, and review the evolution of management since the three previously reported successful repairs at our institution...
- Importance of dural ectasia in phenotypic assessment of Marfan's syndrome
Institute of Radiology, University Hospital S Orsola, Bologna, Italy
Lancet 354:910-3. 1999
..Dural ectasia has been classified as a major diagnostic criterion; however, its prevalence is not known. We aimed to identify the true prevalence of dural ectasia in Marfan's syndrome, and to investigate its relation to aortic pathology...
- Restricted cusp motion in right-left type of bicuspid aortic valves: a new risk marker for aortopathy
Alessandro Della Corte
Department of Cardiothoracic Sciences, Second University of Naples c o Monaldi Hospital, Naples, Italy
J Thorac Cardiovasc Surg 144:360-9, 369.e1. 2012
..This study searched for early imaging predictors of aortopathy in patients with a bicuspid aortic valve with right-left coronary cusp fusion, the most common morphotype...
- Arterial inflow via an axillary artery graft for the severely atheromatous aorta
Y R Baribeau
New England Heart Institute, Catholic Medical Center, Manchester, New Hampshire, USA
Ann Thorac Surg 66:33-7. 1998
..Strategy for severe aortic atheromatous disease identified by intraoperative epiaortic ultrasound remains to be determined. We used axillary artery inflow through graft interposition in an attempt to avoid potential embolization...
- Scan reproducibility of magnetic resonance imaging assessment of aortic atherosclerosis burden
S K Chan
Department of Medicine (Cardiovascular Division, Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
J Cardiovasc Magn Reson 3:331-8. 2001
..62-0.85). These data demonstrate that MRI is a reproducible technique for assessing aortic anatomy and total aortic atherosclerosis, but increased slice density should be considered if serial evaluation of slice-specific data is desired...
- Pulse pressure is an independent predictor for the progression of aortic wall calcification in patients with controlled hyperlipidemia
Department of Clinical Pharmacology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, 812 8582, Japan
Hypertension 43:536-40. 2004
..389, P<0.001) among the blood pressure components. These results suggested that increase in pulse pressure promotes the progression of vascular calcification...
- Management of porcelain aorta and calcified great vessels in coronary artery bypass grafting with off-pump and no-touch technology
H B Bittner
Division of Cardiovascular and Thoracic Surgery, University of Minnesota, Minneapolis 55455, USA
Ann Thorac Surg 72:1378-80. 2001
..We did successful off-pump coronary revascularization in this patient with severely calcified ascending aorta and great vessels, subtotal aortobiiliac stenoses, a history of previous stroke, and right carotid endarterectomy...
- Relationship between hemodynamics and atherosclerosis in aortic arches of apolipoprotein E-null mice on 129S6/SvEvTac and C57BL/6J genetic backgrounds
Department of Pathology and Laboratory Medicine, The University of North Carolina at Chapel Hill, CB 7525, 701 Brinkhous Bullitt Building, Chapel Hill, NC 27599 7525, USA
Atherosclerosis 220:78-85. 2012
..We investigated the relationships between hemodynamics and differential plaque development at the aortic arch of apolipoprotein E (apoE)-null mice on 129S6/SvEvTac (129) and C57BL/6J (B6) genetic backgrounds...
- Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients
Glenn M Chertow
Division of Nephrology, Department of Medicine, University of California San Francisco, San Francisco, CA, USA
Kidney Int 62:245-52. 2002
..Cardiovascular disease is frequent and severe in patients with end-stage renal disease. Disorders of mineral metabolism may contribute by promoting cardiovascular calcification...
- Successful repair of an aortoesophageal fistula with aneurysm from esophageal diverticulum
Department of Thoracic and Cardiovascular Surgery and The Second Department of Surgery, Mie University School of Medicine, Tsu, Japan
Ann Thorac Surg 73:637-9. 2002
..In this case, esophageal diverticulum was diagnosed before the development of an aortoesophageal fistula associated with an aneurysm...
- Inflammation in atherosclerosis: visualizing matrix metalloproteinase action in macrophages in vivo
Jun o Deguchi
Donald W Reynolds Cardiovascular Clinical Research Center, Harvard Medical School, Boston, Massachusetts, USA
Circulation 114:55-62. 2006
..Matrix metalloproteinases (MMPs) in inflamed atherosclerotic plaques may contribute to extracellular matrix remodeling and the onset of acute thrombotic complications...
- Uncommon congenital and acquired aortic diseases: role of multidetector CT angiography
Eric T Kimura-Hayama
Department of Radiology, Division of Computed Tomography, Instituto Nacional de Cardiologia Ignacio Chavez, Juan Badiano 1, Col Seccion XVI, Mexico City, Mexico
Radiographics 30:79-98. 2010
..Radiologists should also be familiar with uncommon aortic diseases, which are divided into those that are congenital in origin and acquired disorders, and with their findings ..
- An unusual origin of proximal coronary bypass anastomosis in a patient with porcelain aorta: how we solved the problem
Department of Cardiovascular Surgery, Insitute of Cardiovascular Diseases of Vojvodina, Sremska Kamenica
Med Pregl 64:215-8. 2011
..Proximal venous anastomosis was created in the Dacron prosthesis of the right carotid artery. Perfusion of the patient was achieved via the graft sutured at the right subclavian artery due to impossibility of direct aortic cannulation...
- Seasonal variation in occurrence of aortic diseases: the database of hospital discharge data of the Emilia-Romagna region, Italy
Department of Internal Medicine, Hospital of the Delta, Azienda Unità Sanitaria Locale di Ferrara, Ferrara, Italy
J Thorac Cardiovasc Surg 135:442-4. 2008
- Cross-sectional relations of peripheral microvascular function, cardiovascular disease risk factors, and aortic stiffness: the Framingham Heart Study
Gary F Mitchell
Cardiovascular Engineering, Inc, Waltham, MA 02453, USA
Circulation 112:3722-8. 2005
..Aortic stiffness and small-artery structure and function share various risk factors; however, relations between these 2 measures of vascular function are complex and incompletely understood...
- Effect of oral calcium carbonate on aortic calcification in apolipoprotein E-deficient (apoE-/-) mice with chronic renal failure
INSERM, Unit 845, Necker Hospital, Universite Paris V, Paris, France
Nephrol Dial Transplant 23:82-90. 2008
..The aim of this study was to reexamine the role of calcium carbonate in vascular calcification and to analyse its effect on aortic calcification-related gene expression in chronic renal failure (CRF)...
- Successful one-stage operation of aortoesophageal fistula from thoracic aneurysm using a rifampicin-soaked synthetic graft
Department of Cardiovascular Surgery, Kinki University School of Medicine, 377 2 Ohno Higashi, Osaka Sayama, Osaka 589 8511, Japan
Interact Cardiovasc Thorac Surg 7:322-4. 2008
..This is the original report of the surgical repair of aortoesophageal fistula using a rifampicin-soaked graft...
- A novel technique of coronary revascularization in porcelain aorta: report of two cases
Meng Yu Wu
Division of Thoracic and Cardiovascular Surgery, Chang Gung Memorial Hospital, Chang Gung University, 5 Fushing Street, Gueishan Shiang, Taoyuan, Taipei, 333, Taiwan
Surg Today 38:157-60. 2008
..This study describes the experience of successful coronary revascularization using bilateral internal thoracic arteries and modified with a composite graft in two patients with a severely atherosclerotic ascending aorta...
- 1,25-Dihydroxyvitamin D3-induced aortic calcifications in experimental uremia: up-regulation of osteoblast markers, calcium-transporting proteins and osterix
Department of Pediatric Nephrology, Campus Virchow Klinikum, Berlin, Germany
J Hypertens 29:339-48. 2011
..We studied mechanisms involved in vitamin D-related vascular calcifications in vivo and in vitro...
- Epiaortic scanning modifies planned intraoperative surgical management but not cerebral embolic load during coronary artery bypass surgery
Department of Anesthesiology, Toronto General Hospital, Eaton North 3 410, 200 Elizabeth Street, Toronto, ON M5G 2C4, Canada
Anesth Analg 106:1611-8. 2008
..We sought to determine the role of epiaortic ultrasound scanning for reducing cerebral embolic load, and whether its use leads to changes of planned intraoperative surgical management in patients undergoing CABG surgery...
- Smoking, smoking cessation and aortic arch calcification in older Chinese: the Guangzhou Biobank Cohort Study
Chao Qiang Jiang
Guangzhou No 12 Hospital Guangzhou Occupational Disease Prevention and Treatment Centre, Guangzhou, People s Republic of China
Atherosclerosis 202:529-34. 2009
..To study the association between smoking, smoking cessation and aortic arc calcification (AAC) in an older Chinese population...
- Left common carotid artery as inflow site in coronary artery bypass grafting
Department of Cardiac Surgery, Centro Cardiologico Monzino, University of Milan, Milan, Italy
Ann Thorac Surg 82:2298-300. 2006
..This technique permitted avoidance of ascending aortic manipulation and reduce the risk of atheromatous embolization...
- 'No touch' techniques for porcelain ascending aorta: comparison between cardiopulmonary bypass with femoral artery cannulation and off-pump myocardial revascularization
Department of Cardiothoracic Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Sackler Faculty of Medicine, Tel Aviv University, Israel
J Card Surg 17:370-6. 2002
..Off-pump coronary artery bypass grafting (OPCAB) confers the benefits of avoiding aortic cannulation and clamping, and may therefore attenuate this risk...
- Clinical evaluation of aortic diseases using nonenhanced MRA with ECG-triggered 3D half-Fourier FSE
Diagnostic Imaging Center, Saiseikai Kumamoto Hospital, Kumamoto, Japan
J Magn Reson Imaging 14:113-9. 2001
..ECG)-triggered 3D half-Fourier fast spin-echo (FSE), was evaluated for the detection and characterization of aortic diseases. Seventy-five consecutive patients with aortic disease underwent the FBI examination on a 1...
- Off-pump axillo-coronary artery bypass grafting with porcelain aorta
Department of Cardiovascular Surgery, Tottori University Hospital, Tottori, Japan
J Card Surg 20:586-8. 2005
..The off-pump axillo-coronary artery bypass grafting seemed to be an appropriate procedure for coronary revascularization with severely diseased ascending aorta...
- Left ventricular hypertrophy is associated with arterial stiffness and vascular calcification in hemodialysis patients
Department of Medicine, Kidney Center, Tokyo Women s Medical University, Tokyo, Japan
Hypertens Res 27:47-52. 2004
..Vascular calcification, which alters the pulsatile dynamics and thereby contributes to an increase in left ventricular load, is the most important contributor to the development of LVH in patients undergoing hemodialysis...
- Validity and usefulness of aortic arch calcification in chest X-ray
Department of Geriatric Medicine, Graduate School of Medicine, University of Tokyo, Tokyo 113 8655, Japan
J Atheroscler Thromb 16:256-64. 2009
..In addition, the validity of the grading and the relationship of this useful grading to clinical risk factors were evaluated...
- Double coronary endarterectomy on the beating heart in two patients with porcelain aorta
Department of Cardiac Surgery, Alkan Hospital, Ankara, Turkey
Ann Thorac Surg 72:620-1. 2001
..In patients with diffuse atherosclerotic coronary artery disease who require endarterectomy, coronary bypass operations can be done safely on the beating heart...
- Endovascular repair of a chronic aortocaval fistula using a thoracic aortic endoprosthesis
Marc E Mitchell
Division of Vascular Surgery, University of Mississippi Medical Center, Jackson, MS, USA
Ann Vasc Surg 23:150-2. 2009
..The ACF was successfully treated with an endoprosthesis designed for the thoracic aorta...
- Aortic diseases--do we need MR techniques?
C A Nienaber
Department of Internal Medicine, University Hospital Hamburg Eppendorf, Germany
Herz 25:331-41. 2000
..MR imaging, flow-mapping and MR angiography is the ideal tool for noninvasive assessment of any kind of aortic diseases. The technique allows to image the aorta both in the thoracic cage and in the abdominal aspects better than ..
- Natural history of vascular calcification in dialysis and transplant patients
Sharon M Moe
Departmrnt of Medicine, Indiana University School of Medicine, 1001 W 10th Street, OPW 526, Indianapolis, IN 46202, USA
Nephrol Dial Transplant 19:2387-93. 2004
..The purpose of the present study was to determine the natural history of coronary artery and aorta calcification by spiral computed tomography (CT) in patients who undergo a renal transplant and patients on haemodialysis...
- A case of unilateral leg edema due to abdominal aortic aneurysm with aortocaval fistula
Department of Surgery, Kurume University School of Medicine, Kurume, Japan
Ann Thorac Cardiovasc Surg 13:135-8. 2007
..ACF is associated with high mortality because it is difficult to control venous bleeding from ACF. Detailed preoperative diagnosis of ACF can provide many advantages to control bleeding from ACF during an operation...
- Presence of abdominal aortic calcification is significantly associated with all-cause and cardiovascular mortality in maintenance hemodialysis patients
Kidney Center, Shirasagi Hospital, Osaka, Japan
Am J Kidney Dis 49:417-25. 2007
- Simple evaluation of aortic arch calcification by chest radiography in hemodialysis patients
Department of Medicine, Kidney Center, Tokyo Women s Medical University, Tokyo, Japan
Hemodial Int 13:301-6. 2009
..001) and pulse pressure (F value=4.54, P=0.037) to be significant independent determinants of AoACS. In conclusion, a simple measurement of AoACS may be useful for inoffice imaging to choose a therapeutic regimen in HD patients...
- Risk factors for progression of aortic arch calcification in patients on maintenance hemodialysis and peritoneal dialysis
Hyun Gyung Kim
Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea
Hemodial Int 15:460-7. 2011
..The results suggest that patients should be carefully managed from the predialysis stage to prevent AoAC progression and to reduce cardiovascular morbidity...
- Magnetic resonance imaging features of aortic diseases
Department of Radiology, Yamaguchi University School of Medicine, 1 1 1 Minamikogushi, Ube, Yamaguchi 755 8505, Japan
Top Magn Reson Imaging 14:253-66. 2003
The usefulness of magnetic resonance imaging (MRI) for aortic diseases is discussed, with special attention given to the MRI features of aortic dissection and Takayasu arteritis...
- Combined aortic valve replacement and coronary artery bypass grafting with in situ arterial grafts for porcelain aorta
Department of Cardiovascular Surgery, National Hospital Kure Medical Center, Hiroshima, Japan
Ann Thorac Cardiovasc Surg 9:206-8. 2003
..On-pump beating heart coronary artery bypass grafting (CABG) can be useful especially for combined complex cardiac surgery...
- Aortotomy and endarterectomy of the ascending aorta for aortic valve replacement in a patient with porcelain aorta
Department of Surgery, Keio University, Shinjuku ku, Tokyo, Japan
Surg Today 35:1000-3. 2005
..During the endarterectomy, we used an elevator designed for hand surgery to exfoliate the calcified intimal plate...
- Management of acute aortic syndrome and chronic aortic dissection
Ian M Nordon
St George s Vascular Institute, St James Wing, St George s Hospital, Blackshaw Road, London SW17 0QT, UK
Cardiovasc Intervent Radiol 34:890-902. 2011
..The best imaging techniques and the evolving role of endovascular techniques in the definitive management of AAS are discussed incorporating strategies to reduce perioperative morbidity...
- Atherosclerotic enlargement of the human abdominal aorta
C K Zarins
Department of Surgery, Division of Vascular Surgery, Suite H 3600, Stanford University Medical Center, Stanford, CA 94305 5642, USA
Atherosclerosis 155:157-64. 2001
..These changes may be predisposing factors for the preferential development of subsequent aneurysmal dilation in the abdominal aorta...
- Warfarin safety and efficacy in patients with thoracic aortic plaque and atrial fibrillation. SPAF TEE Investigators. Stroke Prevention and Atrial Fibrillation. Transesophageal echocardiography
J L Blackshear
Mayo Clinic Jacksonville, Jacksonville, Florida 32224, USA
Am J Cardiol 83:453-5, A9. 1999
..9%/year; 95% CI 3.0 to 12) than those on combination low-dose warfarin (international normalized ratio <1.5) plus aspirin (17.3%/year; 95% CI 11 to 27; p = 0.01)...
- Aortoesophageal fistula: an uncommon complication after stent-graft repair of an aortic thoracic aneurysm
Servicio de Cardiologia, Hospital Virgen de la Victoria, Campus Teatinos s n, 29010 Malaga, Spain
Interact Cardiovasc Thorac Surg 9:683-4. 2009
..To report the incidence and management of aortoesophageal fistula (AEF) secondary to endovascular stent-graft repair of the descending thoracic aorta...
- Aortic plaque morphology and vascular events: a follow-up study in patients with ischemic stroke. FAPS Investigators. French Study of Aortic Plaques in Stroke
Service de cardiologie, Saint Antoine University and Medical School, Paris, France
Circulation 96:3838-41. 1997
..The purpose of this study was to evaluate the impact, if any, of plaque morphology (ulceration, hypoechoic plaques or calcification) on the risk of subsequent vascular events...
- Atherosclerotic disease of the proximal aorta and the risk of vascular events in a population-based cohort: the Aortic Plaques and Risk of Ischemic Stroke (APRIS) study
Departments of Medicine, Columbia University, New York, NY 10032, USA
Stroke 40:2313-8. 2009
..However, this association in the general population is unclear. We sought to assess whether proximal aortic plaques are associated with vascular events in a community-based cohort...
- Mobile aortic atheroma and systemic emboli: efficacy of anticoagulation and influence of plaque morphology on recurrent stroke
F A Dressler
Department of Internal Medicine and Pathology, Saint Louis University Health Sciences Center, Missouri 63110, USA
J Am Coll Cardiol 31:134-8. 1998
..We sought to determine the influence of plaque morphology and warfarin anticoagulation on the risk of recurrent emboli in patients with mobile aortic atheroma...
- Endovascular treatment of thoracic aortic disease: four years of experience
Alessandro S Bortone
Dipartimento Emergenza e Trapianti d Organo, Sezione di Cardiochirurgia, Piazza Giulio Cesare 11 70124 Bari, Italy
Circulation 110:II262-7. 2004
..The aim of this retrospective study is to investigate efficacy and middle-term results of the stent graft treatment for diseases of descending thoracic aorta...
- Treatment of type II endoleaks associated with left subclavian artery coverage during thoracic aortic stent grafting
Mark D Peterson
Division of Cardiovascular Surgery, Arizona Heart Institute, Phoenix, Ariz 85006, USA
J Thorac Cardiovasc Surg 136:1193-9. 2008
..It is currently unclear how best to manage these patients to prevent persistent risk of aneurysm expansion or rupture. We report our experience with a minimally invasive endovascular repair of the covered left subclavian artery...
- New insight in aetiopathogenesis of aortic diseases
Surgical Research Center, Paris 12 University, CNRS EAC 7054, 8 rue du General Sarrail, 94010 Creteil Cedex, France
Eur J Vasc Endovasc Surg 37:531-7. 2009
..This article focusses on aneurysms and dissections, and excludes causes related to infection, systemic inflammatory diseases and trauma...