dissecting aneurysm

Summary

Summary: Splitting or dissection of an arterial wall by blood entering through an intimal tear or by interstitial hemorrhage. It is most common in the aorta.

Top Publications

  1. ncbi Does the arterial cannulation site for circulatory arrest influence stroke risk?
    Lars G Svensson
    Department of Thoracic Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ann Thorac Surg 78:1274-84; discussion 1274-84. 2004
  2. ncbi Mutations in transforming growth factor-beta receptor type II cause familial thoracic aortic aneurysms and dissections
    Hariyadarshi Pannu
    Department of Internal Medicine, Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX, USA
    Circulation 112:513-20. 2005
  3. ncbi Endovascular treatment of thoracic aortic diseases: combined experience from the EUROSTAR and United Kingdom Thoracic Endograft registries
    Lina J Leurs
    EUROSTAR and UK Thoracic Aortic Data Registry, Catharina Hospital, Eindhoven, The Netherlands
    J Vasc Surg 40:670-9; discussion 679-80. 2004
  4. ncbi Endovascular stent-graft placement for the treatment of acute aortic dissection
    M D Dake
    Division of Cardiovascular and Interventional Radiology, Stanford University School of Medicine, Calif, USA
    N Engl J Med 340:1546-52. 1999
  5. ncbi Successful staged treatment for ruptured blister-like dissecting aneurysm of the intracranial internal carotid artery: acute GDC embolization for the blister-like aneurysm followed by proximal occlusion with extracranial-intracranial bypass in the chronic
    M S Islam
    Department of Neurosurgery, Kuroishi City Hospital, Kuroishi, Aomori, Japan
    Minim Invasive Neurosurg 47:165-8. 2004
  6. ncbi Gender differences and predictors of mortality in spontaneous coronary artery dissection: a review of reported cases
    Ellen A Thompson
    Division of Cardiovascular Services, Marsall University, Huntington, West Virginia 25702, USA
    J Invasive Cardiol 17:59-61. 2005
  7. ncbi Thoracic aortic aneurysm and dissection: increasing prevalence and improved outcomes reported in a nationwide population-based study of more than 14,000 cases from 1987 to 2002
    Christian Olsson
    Department of Cardiothoracic Surgery, Uppsala University Hospital, Uppsala, Sweden
    Circulation 114:2611-8. 2006
  8. ncbi Partial thrombosis of the false lumen in patients with acute type B aortic dissection
    Thomas T Tsai
    Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, MI 48109 5853, USA
    N Engl J Med 357:349-59. 2007
  9. ncbi Suspected aortic dissection and other aortic disorders: multi-detector row CT in 373 cases in the emergency setting
    Robert G Hayter
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, 02115, USA
    Radiology 238:841-52. 2006
  10. ncbi Contemporary results of surgery in acute type A aortic dissection: The International Registry of Acute Aortic Dissection experience
    Santi Trimarchi
    Istituto Policlinico S Donato, Milanese, Italy
    J Thorac Cardiovasc Surg 129:112-22. 2005

Detail Information

Publications233 found, 100 shown here

  1. ncbi Does the arterial cannulation site for circulatory arrest influence stroke risk?
    Lars G Svensson
    Department of Thoracic Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ann Thorac Surg 78:1274-84; discussion 1274-84. 2004
    ..We investigated whether axillary/subclavian artery inflow with a side graft decreases the risk of stroke versus cannulation at other sites during hypothermic circulatory arrest...
  2. ncbi Mutations in transforming growth factor-beta receptor type II cause familial thoracic aortic aneurysms and dissections
    Hariyadarshi Pannu
    Department of Internal Medicine, Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX, USA
    Circulation 112:513-20. 2005
    ..Having mapped a TAAD locus to 3p24-25, we sequenced the gene for transforming growth factor-beta receptor type II (TGFBR2) to determine whether mutations in this gene resulted in familial TAAD...
  3. ncbi Endovascular treatment of thoracic aortic diseases: combined experience from the EUROSTAR and United Kingdom Thoracic Endograft registries
    Lina J Leurs
    EUROSTAR and UK Thoracic Aortic Data Registry, Catharina Hospital, Eindhoven, The Netherlands
    J Vasc Surg 40:670-9; discussion 679-80. 2004
    ....
  4. ncbi Endovascular stent-graft placement for the treatment of acute aortic dissection
    M D Dake
    Division of Cardiovascular and Interventional Radiology, Stanford University School of Medicine, Calif, USA
    N Engl J Med 340:1546-52. 1999
    ..Irrespective of the form of treatment, the associated mortality and morbidity are considerable...
  5. ncbi Successful staged treatment for ruptured blister-like dissecting aneurysm of the intracranial internal carotid artery: acute GDC embolization for the blister-like aneurysm followed by proximal occlusion with extracranial-intracranial bypass in the chronic
    M S Islam
    Department of Neurosurgery, Kuroishi City Hospital, Kuroishi, Aomori, Japan
    Minim Invasive Neurosurg 47:165-8. 2004
    The surgical treatment of ruptured blister-like dissecting aneurysm on the internal carotid artery (ICA) is still controversial...
  6. ncbi Gender differences and predictors of mortality in spontaneous coronary artery dissection: a review of reported cases
    Ellen A Thompson
    Division of Cardiovascular Services, Marsall University, Huntington, West Virginia 25702, USA
    J Invasive Cardiol 17:59-61. 2005
    ..50 to 12.2), non-treatment (OR 35.5; 95% CI 10.7 to 118.1), and earlier decade of diagnosis (OR 0.28 per increase in decade after 1980; 95% CI 0.16 to 0.49). Survival was no different by treatment type and did improve over time...
  7. ncbi Thoracic aortic aneurysm and dissection: increasing prevalence and improved outcomes reported in a nationwide population-based study of more than 14,000 cases from 1987 to 2002
    Christian Olsson
    Department of Cardiothoracic Surgery, Uppsala University Hospital, Uppsala, Sweden
    Circulation 114:2611-8. 2006
    ..The objective of the present study was to reappraise epidemiology and long-term outcomes in subjects with thoracic aortic disease in a large contemporary population...
  8. ncbi Partial thrombosis of the false lumen in patients with acute type B aortic dissection
    Thomas T Tsai
    Department of Internal Medicine, Division of Cardiovascular Medicine, University of Michigan Medical Center, Ann Arbor, MI 48109 5853, USA
    N Engl J Med 357:349-59. 2007
    ..Patency or thrombosis of the false lumen in type B acute aortic dissection has been found to predict outcomes. The prognostic implications of partial thrombosis of the false lumen have not yet been elucidated...
  9. ncbi Suspected aortic dissection and other aortic disorders: multi-detector row CT in 373 cases in the emergency setting
    Robert G Hayter
    Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Boston, 02115, USA
    Radiology 238:841-52. 2006
    ..To retrospectively review the authors' experience with multi-detector row computed tomography (CT) for detection of aortic dissection in the emergency setting...
  10. ncbi Contemporary results of surgery in acute type A aortic dissection: The International Registry of Acute Aortic Dissection experience
    Santi Trimarchi
    Istituto Policlinico S Donato, Milanese, Italy
    J Thorac Cardiovasc Surg 129:112-22. 2005
    ....
  11. ncbi Aortoesophageal fistula secondary to stent-graft repair of the thoracic aorta
    Holger Eggebrecht
    Department of Cardiology, West German Heart Center, University of Duisburg Essen, Hufelandstrasse 55, 45122 Essen, Germany
    J Endovasc Ther 11:161-7. 2004
    ..To report the incidence and management of aortoesophageal fistula (AEF) secondary to endovascular stent-graft repair of the descending thoracic aorta...
  12. ncbi Endovascular treatment of isolated dissecting aneurysm of the posterior inferior cerebellar artery
    S Maimon
    Department of Radiology, Interventional Neuroradiology Unit, Rabin Medical Center, Beilinson Campus, Petach Tikva, Israel
    AJNR Am J Neuroradiol 27:527-32. 2006
    ..The purpose of this article is to show that endovascular treatment of dissecting aneurysms of the PICA can be effective and can allow the patient to avoid the complications associated with surgery...
  13. ncbi Aortic root growth in men and women with the Marfan's syndrome
    Lilian J Meijboom
    Department of Cardiology, Academic Medical Centre, Amsterdam, The Netherlands
    Am J Cardiol 96:1441-4. 2005
    ..In conclusion, guidelines should take gender differences into account, and therefore, the investigators propose reducing the threshold for elective aortic root replacement in women with MS by 5 mm...
  14. pmc Diagnosis and management of patients with aortic dissection
    Huseyin Ince
    Department of Internal Medicine, Division of Cardiology at the University Hospital Rostock, Rostock School of Medicine, Rostock, Germany
    Heart 93:266-70. 2007
  15. pmc Right pulmonary artery occlusion by an acute dissecting aneurysm of the ascending aorta
    Ravi J De Silva
    Papworth Hospital NHS Trust, Papworth Everard, Cambridgeshire CB3 8RE, UK
    J Cardiothorac Surg 1:29. 2006
    ..The extremely rare finding of intramural thrombus occluding the right pulmonary artery was seen at post mortem...
  16. ncbi Treatment of a spontaneous intracranial dissecting aneurysm with stent-assisted coil embolization
    Keiko Irie
    Department of Neurosurgery, Fujita Health University, 1 98 Dengakugakubo, Kutsukakecho, Toyoake, 470 1192 Aichi, Japan
    Neuroradiology 45:825-9. 2003
    ..Endovascular treatment for cerebral aneurysms has become widespread; however, the dissecting aneurysm is still difficult to treat if the parent artery has to be preserved...
  17. ncbi Role and results of surgery in acute type B aortic dissection: insights from the International Registry of Acute Aortic Dissection (IRAD)
    Santi Trimarchi
    Cardiovascular Center E Malan, Policlinico San Donato, Via Morandi 30, 20097 San Donato Milanese, Italy
    Circulation 114:I357-64. 2006
    ....
  18. ncbi Dissecting aneurysm of the basilar artery as a cause of orgasmic headache
    In Soo Joo
    Headache 45:956-9. 2005
    ..Both magnetic resonance angiography and conventional angiogram of the brain confirmed dissecting aneurysm of the basilar artery...
  19. ncbi Immediate versus delayed endovascular treatment of post-traumatic aortic pseudoaneurysms and type B dissections: retrospective analysis and premises to the upcoming European trial
    Alessandro S Bortone
    Division of Cardiovascular Surgery, Department of Emergency and Transplantation, University of Bari School of Medicine, Bari, Italy
    Circulation 106:I234-40. 2002
    ....
  20. ncbi Staged repair of a chronic dissecting aneurysm with the two elephant trunks technique
    Chul Hyun Park
    Department of Thoracic and Cardiovascular Surgery, Gil Hospital, Gachon University of Medicine and Science, Incheon, Republic of Korea
    Ann Thorac Surg 88:e69-71. 2009
    ..The general procedure is to excise a generous portion of the dissecting septum distally for a chronic dissecting aneurysm of the descending thoracic aorta. We present the "two elephant trunks" technique...
  21. ncbi Antegrade recanalization of a completely embolized vertebral artery after endovascular treatment of a ruptured intracranial dissecting aneurysm. Report of two cases
    Motoshi Sawada
    Department of Neurosurgery, Matsunami General Hospital, Japan
    J Neurosurg 102:161-6. 2005
    ..Based on these unique cases, the authors suggest that a careful angiographic follow up of dissecting aneurysms is required, even in patients successfully treated with endovascular occlusion of the affected artery and aneurysm...
  22. ncbi Antegrade recanalization of parent artery in internal trapping of vertebral artery dissecting aneurysm: a case report
    Seung Kug Baik
    Department of Diagnostic Radiology, Kyungpook National University, Daegu 700 72, Korea
    Surg Neurol 68:108-11; discussion 111. 2007
    ..detachable coils yet antegrade recanalization of the occluded vertebral artery, in the vertebral artery dissecting aneurysm. Possible explanations for the antegrade recanalization of the occluded vertebral artery and lessons from ..
  23. ncbi [Application of endovascular covered stent for treating vertebral dissecting aneurysm and carotid-cavernous fistula]
    Hao Ding
    Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu Sichuan, 610041, P R China
    Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 23:215-8. 2009
    To investigate the therapeutic effects of endovascular covered stent on vertebral dissecting aneurysm and carotid-cavernous fistula (CCF).
  24. ncbi Endovascular treatment of thoracic aortic disease: four years of experience
    Alessandro S Bortone
    Dipartimento Emergenza e Trapianti d Organo, Sezione di Cardiochirurgia, Piazza Giulio Cesare 11 70124 Bari, Italy
    Circulation 110:II262-7. 2004
    ..The aim of this retrospective study is to investigate efficacy and middle-term results of the stent graft treatment for diseases of descending thoracic aorta...
  25. ncbi Ascending aortic dissecting aneurysm with isolated right pulmonary arterial medial intramural hematoma
    Jiunn Jye Sheu
    Department of Cardiovascular and Thoracic Surgery, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University, College of Medicine, Kaohsiung, Taiwan
    Ann Thorac Surg 85:2127-8. 2008
    ..We report an extremely unusual case of an ascending aortic dissecting aneurysm associated with an isolated medial intramural hematoma in the right pulmonary artery in an 86-year-old ..
  26. ncbi Arterial reconstruction by direct surgical clipping of a basilar artery dissecting aneurysm after failed vertebral artery occlusion: technical case report and literature review
    Mir Jafer Ali
    Department of Neurological Surgery, Northwestern University Medical School, 233 East Erie Street, Chicago, IL 60611, USA
    Neurosurgery 52:1475-80; discussion 1480-1. 2003
    ..An enlarging pseudoaneurysm in the chronic phase, however, may have sufficient tissue for clip reconstruction. We present a case in which this strategy was used successfully...
  27. ncbi Coronary artery dissection during pregnancy and the postpartum period: two case reports and review of literature
    A K Koul
    Division of Cardiology, Maimonides Medical Center, Brooklyn, New York 11219, USA
    Catheter Cardiovasc Interv 52:88-94. 2001
    ..Diagnostic and therapeutic considerations of this unique clinical entity are discussed and reviewed...
  28. ncbi Diagnosis of acute aortic dissection by D-dimer: the International Registry of Acute Aortic Dissection Substudy on Biomarkers (IRAD-Bio) experience
    Toru Suzuki
    Department of Cardiovascular Medicine, Graduate School of Medicine, The University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo 113 8655 Japan
    Circulation 119:2702-7. 2009
    ..We evaluated the diagnostic performance of D-dimer testing in a study population of patients with suspected aortic dissection...
  29. ncbi Mutations in myosin heavy chain 11 cause a syndrome associating thoracic aortic aneurysm/aortic dissection and patent ductus arteriosus
    Limin Zhu
    Assistance Publique Hopitaux de Paris, Hopital Europeen Georges Pompidou, Département de génétique, 75015 Paris, France
    Nat Genet 38:343-9. 2006
    ..Human MYH11 gene mutations provide the first example of a direct change in a specific SMC protein leading to an inherited arterial disease...
  30. ncbi Simple and useful tests for discriminating between acute aortic dissection of the ascending aorta and acute myocardial infarction in the emergency setting
    Hiroshi Hazui
    Department of Emergency Medicine, Osaka Mishima Emergency and Critical Care Center, Japan
    Circ J 69:677-82. 2005
    ..The aim of this study was to find a simple test to distinguish such patients...
  31. ncbi Dissecting aneurysm of basilar artery presenting with recurrent subarachnoid hemorrhage
    T Nakahara
    Department of Neurosurgery, Hiroshima University School of Medicine, Japan
    Neurosurg Rev 22:155-8. 1999
    ..A 63-year-old man who had SAH repeatedly from a ruptured basilar dissecting aneurysm was treated with endovascular occlusion of the unilateral vertebral artery...
  32. ncbi Dissecting aneurysm of the anterior cerebral artery with severe subarachnoid hemorrhage during treatment for cerebral infarction
    Shoko M Yamada
    Department of Neurosurgery, Teikyo University School of Medicine, Mizonokuchi Hospital, Kawasaki
    Intern Med 42:433-5. 2003
    ..woman succumbed to a subarachnoid hemorrhage (SAH) during antiplatelet therapy for ischemia caused by a dissecting aneurysm at the anterior cerebral artery, which was identified by conventional angiography on day 11 after admission...
  33. ncbi Thoracic aortic emergencies: impact of endovascular surgery
    Gabriele Iannelli
    Department of Cardiac Surgery, University Federico II of Naples, Naples, Italy
    Ann Thorac Surg 77:591-6. 2004
    ..To obviate this risk, endovascular surgery is considered to be a valid alternative procedure...
  34. ncbi Trapping and revascularization for a dissecting aneurysm of the proximal posteroinferior cerebellar artery: technical case report and review of the literature
    Mir Jafer Ali
    Department of Neurological Surgery, Northwestern University Medical School, Chicago, Illinois 60611, USA
    Neurosurgery 51:258-62; discussion 262-3. 2002
    ..We report this case to review this rare topic and to present our perspective on the indications for and the effectiveness of trapping and revascularization for proximal PICA dissections that cause hemorrhage...
  35. ncbi Spontaneous coronary artery dissection: report of two cases and a 50-year review of the literature
    Raghunandan Kamineni
    Sarver Heart Center, 1501 N Campbell Avenue, University of Arizona Health Sciences Center, Tucson, Arizona 85724, USA
    Cardiol Rev 10:279-84. 2002
    ..We report two cases of SCAD successfully identified and treated with coronary stenting as well as a comprehensive review of cases of SCAD published since 1952...
  36. ncbi Diagnostic and prognostic value of circulating D-Dimers in patients with acute aortic dissection
    Patrick Ohlmann
    Fédération of cardiologie, Service de chirurgie cardiaque, Hopitaux Universitaires de Strasbourg, France
    Crit Care Med 34:1358-64. 2006
    ..We sought to determine whether assessing D-Dimer might be helpful for the management of acute aortic dissection (AAD)...
  37. ncbi Aortic dissection: new frontiers in diagnosis and management: Part I: from etiology to diagnostic strategies
    Christoph A Nienaber
    Division of Cardiology, University Hospital Rostock, Rostock School of Medicine, Ernst Heydemann Str 6, 18057 Rostock, Germany
    Circulation 108:628-35. 2003
  38. ncbi [Subarachnoid hemorrhage due to ruptured dissecting aneurysm of peripheral superior cerebellar artery]
    Tomohiro Araki
    Department of Neurosurgery, Mie University School of Medicine, 2 174 Edobashi, Tsu City, Mie 514 8507, Japan
    No Shinkei Geka 30:1345-51. 2002
    The peripheral superior cerebellar artery (SCA) dissecting aneurysm (DA) is extremely rare, with only 4 cases (including our case) having been reported...
  39. ncbi Soluble elastin fragments in serum are elevated in acute aortic dissection
    Tadashi Shinohara
    Department of Internal Medicine I, National Defense Medical College, Saitama, Japan
    Arterioscler Thromb Vasc Biol 23:1839-44. 2003
    ..We aimed to establish an enzyme-linked immunosorbent assay for measuring soluble elastin fragments (sELAF) in serum and to reveal its usefulness in diagnosing acute aortic dissection (AAD)...
  40. ncbi Midterm outcomes of femoral arteries after percutaneous endovascular aortic repair using the Preclose technique
    W Anthony Lee
    University of Florida, Division of Vascular Surgery and Endovascular Therapy, Gainesville, FL 32610 0286, USA
    J Vasc Surg 47:919-23. 2008
    ..The purpose of this study is to examine the late outcomes of those femoral arteries repaired in this manner...
  41. ncbi Operative delay for peripheral malperfusion syndrome in acute type A aortic dissection: a long-term analysis
    Himanshu J Patel
    Department of Surgery, University of Michigan Hospitals, Ann Arbor, Mich, USA
    J Thorac Cardiovasc Surg 135:1288-95; discussion 1295-6. 2008
    ..This study evaluates the late outcomes with this approach...
  42. ncbi Mediastinitis following graft replacement of the ascending aorta: conservative approach by omental transposition
    N Luciani
    Department of Cardiac Surgery, Policlinico A. Gemelli University Hospital, Catholic University of the Sacred Heart, Rome, Italy
    Eur J Cardiothorac Surg 20:418-20. 2001
    ..Prompt conservative surgical treatment including omental transposition can be effective in the treatment of mediastinitis following graft replacement of the ascending aorta...
  43. ncbi [Dissecting aneurysm of the anterior cerebral artery with later development of collateral circulation: a case report]
    K Nakanishi
    Department of Neurosurgery, Kinki University School of Medicine, 377-2, Ohno-Higashi, Osaka-Sayama, Osaka 589-8511, Japan
    No Shinkei Geka 29:781-5. 2001
    Intracranial dissecting aneurysm (DA) is much less frequent than berry aneurysm. Such dissection involves mostly the vertebral and basilar arteries, followed by the internal carotid and middle cerebral arteries...
  44. ncbi Intentional left subclavian artery occlusion by thoracic aortic stent-grafts without surgical transposition
    K A Hausegger
    Department of Radiology, University Hospital Graz, Austria
    J Endovasc Ther 8:472-6. 2001
    ..To report the consequences of endoluminal deployment of stent-grafts in the thoracic aorta with intentional occlusion of the left subclavian artery...
  45. ncbi Contemporary management of aortic branch compromise resulting from acute aortic dissection
    S R Lauterbach
    Division of Vascular Surgery and the Thoracic Aortic Center, Massachusetts General Hospital, and Department of Surgery, Harvard Medical School, Boston, Mass 02114, USA
    J Vasc Surg 33:1185-92. 2001
    ..Increased awareness and prompt, specific management of PVCs, in particular when visceral ischemia is present, have contributed to improved outcomes in patients with AD...
  46. ncbi Surgical pathology of the ascending aorta: a clinicopathologic study of 513 cases
    James L Homme
    Mayo Medical School, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 30:1159-68. 2006
    ..ICTD, systemic hypertension, and bicuspid aortic valve were common comorbid findings. Giant cell aortitis occured predominantly in women, usually without systemic disease...
  47. ncbi Elective endovascular treatment of descending thoracic aortic aneurysms and chronic dissections with stent-grafts
    J Y Won
    Department of Diagnostic Radiology, Yonsei University College of Medicine, Seodaemun-gu, Seoul, Korea
    J Vasc Interv Radiol 12:575-82. 2001
    ..CONCLUSIONS: For treatment of aortic dissection and saccular aneurysm of the descending thoracic aorta, endovascular stent-graft repair may be a technically feasible and effective treatment modality...
  48. ncbi Clinical picture of intracranial non-traumatic dissecting aneurysm
    A Yamaura
    Department of Neurological Surgery, Chiba University School of Medicine, Japan
    Neuropathology 20:85-90. 2000
    ..Good recovery was achieved in 64% of all patients. Outcome was better in patients with no subarachnoid hemorrhage compared with those with hemorrhage...
  49. ncbi Diagnosis of acute thoracic aortic dissection in the emergency department
    P R Sullivan
    Department of Emergency Medicine, University of Pittsburgh, PA, USA
    Am J Emerg Med 18:46-50. 2000
    ..Thirteen of 39 (33%) painful presentations involved abdominal pain; EPs suspected AD in 1 of 13 (8%). EPs suspected the diagnosis in 43% of acute AD; location of pain was most predictive of a suspected diagnosis...
  50. ncbi Staged therapeutic approach in spontaneous coronary dissection
    Siamak Aliyary
    Department of Cardiology, Medisch Spectrum Twente, Enschede, The Netherlands
    Ann Thorac Surg 83:1879-81. 2007
    ..While she was on aortic balloon counterpulsation the patient underwent a cesarean section and gave birth to a healthy child. Subsequently she successfully underwent off-pump coronary artery bypass surgery...
  51. ncbi Does this patient have an acute thoracic aortic dissection?
    Michael Klompas
    Department of Medicine, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115, USA
    JAMA 287:2262-72. 2002
    ..The diagnosis of acute thoracic aortic dissection is difficult to make and often missed...
  52. ncbi Changes in false lumen after transluminal stent-graft placement in aortic dissections: six years' experience
    Hitoshi Kusagawa
    Department of Thoracic and Cardiovascular Surgery, Mie University School of Medicine, Tsu, Mie, Japan
    Circulation 111:2951-7. 2005
    ..Treatment of aortic dissections with TSGPs has resulted in good early results, but the long-term results and changes in the false lumen have not been elucidated in detail...
  53. ncbi Feasibility of the Inoue single-branched stent-graft implantation for thoracic aortic aneurysm or dissection involving the left subclavian artery: short- to medium-term results in 17 patients
    Naritatsu Saito
    Department of Cardiovascular Medicine, Graduate School of Medicine, Kyoto University, Japan
    J Vasc Surg 41:206-12; discussion 212. 2005
    ..This study assessed the short- to medium-term clinical results of the Inoue single-branched stent graft for repair of thoracic aortic aneurysms or dissections involving the left subclavian artery...
  54. ncbi Nonsurgical reconstruction of thoracic aortic dissection by stent-graft placement
    C A Nienaber
    Department of Cardiology, University Hospital Eppendorf, Hamburg, Germany
    N Engl J Med 340:1539-45. 1999
    ..Proximal dissection requires surgery, but the appropriate treatment of distal thoracic aortic dissection has not been determined, because surgery has failed to improve the prognosis...
  55. ncbi Surgical delay for acute type A dissection with malperfusion
    G M Deeb
    Section of Thoracic Surgery, The University of Michigan Hospitals, Ann Arbor 48109 0344, USA
    Ann Thorac Surg 64:1669-75; discussion 1675-7. 1997
    ..Intraoperative deaths were secondary to pulmonary failure resulting from capillary leak; the remaining patients died of multiorgan failure resulting from reperfusion injury...
  56. ncbi Aortic dissection after forceful coughing
    T J Papadimos
    Anaesthesia 61:71-2. 2006
  57. ncbi INvestigation of STEnt grafts in patients with type B Aortic Dissection: design of the INSTEAD trial--a prospective, multicenter, European randomized trial
    Christoph A Nienaber
    Division of Cardiology and Internal Medicine Department, Rostock University, Germany
    Am Heart J 149:592-9. 2005
    ....
  58. pmc Third-nerve palsy heralding dissecting aneurysm of posterior cerebral artery: digital subtraction angiography and magnetic resonance appearance
    M Nistri
    J Neurol Neurosurg Psychiatry 78:197-8. 2007
  59. ncbi Expert consensus document on the treatment of descending thoracic aortic disease using endovascular stent-grafts
    Lars G Svensson
    Center for Aortic Surgery and Marfan Syndrome Clinic, Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Ann Thorac Surg 85:S1-41. 2008
    ....
  60. ncbi [Intrathecal baclofen therapy for spastic paraparesis due to aortic dissecting aneurysm; recent progress in treatment strategy]
    T Nakajima
    Department of Neurosurgery, Tokyo Women s Medical University, Tokyo, Japan
    Kyobu Geka 62:1039-42. 2009
    ..More promotive enlightenment if ITB is indispensable for enhancement of its medical benefit in Japan...
  61. ncbi Post-traumatic dissecting aneurysm of extracranial internal carotid artery: endovascular treatment with stenting
    F Simionato
    Department of Neuroradiology, San Raffaele Hospital, Milan, Italy
    Neuroradiology 41:543-7. 1999
    ..We report a post-traumatic dissecting aneurysm of the extracranial internal carotid artery successfully treated with stenting via a transfemoral approach.
  62. ncbi Arterial dissection and stroke in children
    H J Fullerton
    Department of Neurology, University of California, San Francisco 94143 0114, USA
    Neurology 57:1155-60. 2001
    ..To describe the clinical characteristics of dissections of cerebral arteries in children...
  63. ncbi Endovascular treatment of a basilar artery dissecting aneurysm
    Cristiane Borges Patroclo
    Departments of Neurology and Radiology, Hospital das Clinicas, Sao Paulo University, Avenida Dr Enéas de Carvalho Aguiar 255, Sao Paulo, SP, Brazil
    Arq Neuropsiquiatr 65:1012-4. 2007
    ..Clinical and radiological results were excellent and no complications were observed, suggesting that BA stenting and coil embolization may be a safe and effective treatment for this condition...
  64. ncbi Serious complications following endovascular thoracic aortic stent-graft repair for type B dissection
    Beate Neuhauser
    Department of Vascular Surgery, University Hospital Innsbruck, Austria
    Eur J Cardiothorac Surg 33:58-63. 2008
    ..To describe our experience with endovascular stent-graft repairs in type B aortic dissection focusing on serious secondary complications resulting in immediate or late conversion to open repair...
  65. ncbi Surgical treatment of dissecting aneurysm of the interventricular septum
    Qingyu Wu
    Department of Cardiac Surgery, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, People s Republic of China
    Eur J Cardiothorac Surg 22:517-20. 2002
    We reviewed our experience in the surgical treatment of an extremely rare disease, dissecting aneurysm of the interventricular septum (DAIS)...
  66. ncbi Endovascular repair of thoracic aortic lesions with the Zenith TX1 and TX2 thoracic grafts: intermediate-term results
    Roy K Greenberg
    The Cleveland Clinic Foundation, OH 44195, USA
    J Vasc Surg 41:589-96. 2005
    ..This prospective study was designed to assess the technical success and outcome after patients with thoracic aortic pathology at high risk for conventional therapy were treated with the Zenith TX1 and TX2 endovascular graft...
  67. ncbi Characterizing the young patient with aortic dissection: results from the International Registry of Aortic Dissection (IRAD)
    James L Januzzi
    Thoracic Aorta Center and Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, USA
    J Am Coll Cardiol 43:665-9. 2004
    ..The goal of this study was to better characterize the young patient with aortic dissection (AoD)...
  68. ncbi MDCT angiography of acute chest pain: evaluation of ECG-gated and nongated techniques
    Vassilios D Raptopoulos
    Department of Radiology, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    AJR Am J Roentgenol 186:S346-56. 2006
    ..The objective of our study was to compare MDCT angiography protocols used in patients with acute chest pain caused by vascular, nonvascular, and cardiac abnormalities...
  69. ncbi A prospective study of medically treated acute type B aortic dissection
    A Winnerkvist
    Department of Cardiothoracic Surgery and Anesthesiology, Karolinska University Hospital, Stockholm, Sweden
    Eur J Vasc Endovasc Surg 32:349-55. 2006
    ..To study prospectively aneurysm formation, need of surgery, incidence of rupture and mortality in patients with conservatively treated acute type B aortic dissection...
  70. ncbi Outcomes and survival in surgical treatment of descending thoracic aorta with acute dissection
    John Bozinovski
    Cardiovascular Surgery Service, the Texas Heart Institute at St Luke s Episcopal Hospital, Division of Cardiothoracic Surgery, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas 77030, USA
    Ann Thorac Surg 85:965-70; discussion 970-1. 2008
    ..We report the outcomes of 76 consecutive patients who underwent surgical repair of the descending thoracic aorta or the thoracoabdominal aorta for acute dissection...
  71. pmc Is there a place for D-dimers in acute type A aortic dissection?
    F F Immer
    Heart 92:727-8. 2006
    ..Plasma concentrations of D-dimer may prove a valuable addition in the diagnostic work-up of acute type A aortic dissection, but not as means of predicting mortality...
  72. ncbi Familial thoracic aortic aneurysms and dissections: three families with early-onset ascending and descending aortic dissections in women
    Van Tran-Fadulu
    Department of Internal Medicine, Division of Medical Genetics, The University of Texas Medical School at Houston, Houston, Texas 77030, USA
    Am J Med Genet A 140:1196-202. 2006
    ..Thus, a novel unidentified loci may be responsible for the phenotype in these three families...
  73. ncbi D-dimer in ruling out acute aortic dissection: a systematic review and prospective cohort study
    Gottfried Sodeck
    Department of Emergency Medicine, Medical University Vienna, Vienna, Austria
    Eur Heart J 28:3067-75. 2007
    ..Blood D-dimer testing has been proposed as diagnostic marker with high sensitivity for exclusion of acute aortic dissection (AAD). We performed a systematic review and validated the findings in a prospective patient cohort...
  74. ncbi Endograft exclusion of acute and chronic descending thoracic aortic dissections
    Tae K Song
    Division of Vascular, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Harbor UCLA Medical Center, Torrance, CA 90502, USA
    J Vasc Surg 43:247-58. 2006
    ....
  75. ncbi Treatment of aortic disease in patients with Marfan syndrome
    Dianna M Milewicz
    Department of Internal Medicine, University of Texas Medical School at Houston, 6431 Fannin, MSB 4 202, Houston, TX 77030, USA
    Circulation 111:e150-7. 2005
  76. ncbi Serum D-dimer is a sensitive test for the detection of acute aortic dissection: a pooled meta-analysis
    Keith A Marill
    Department of Emergency Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    J Emerg Med 34:367-76. 2008
    ..Specificity ranged from 40% to 100%. Serum D-dimer is sensitive for acute aortic dissection and potentially represents a useful test for patients who present with a low likelihood of this disease...
  77. ncbi Electrocardiographically gated 16-section CT of the thorax: cardiac motion suppression
    Lars K Hofmann
    Department of Radiology, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    Radiology 233:927-33. 2004
    ..Best image quality was achieved by referencing image reconstruction to middiastole (50%-60%) for the left coronary artery, aortic root, and ascending aorta. The pulmonary arteries are best displayed during mid- to late diastole (80%)...
  78. ncbi A rapid bedside D-dimer assay (cardiac D-dimer) for screening of clinically suspected acute aortic dissection
    Koichi Akutsu
    Intensive and Coronary Care Unit, Nippon Medical School, Tokyo, Japan
    Circ J 69:397-403. 2005
    ..A rapid laboratory test for diagnosis of acute aortic dissection (AAD) has not been available. We performed this prospective study to determine the utility of a rapid bedside D-dimer (DD) assay for detection of AAD...
  79. ncbi Spontaneous dissection of the left main coronary artery treated with percutaneous coronary stenting
    Mimi Q Le
    University of Rochester Medical Center, Cardiology Unit, Rochester, NY 14642, USA
    J Invasive Cardiol 19:E218-21. 2007
    ..We report a case of spontaneous dissection of the left main coronary artery in a young woman who was successfully treated with percutaneous coronary stent implantation...
  80. doi D-Dimer in ruling out acute aortic dissection: sensitivity is not 100%
    Patrick Ohlmann
    Eur Heart J 29:828-9; author reply 829. 2008
  81. ncbi Comparison of aortic dissection in patients with and without Marfan's syndrome (results from the International Registry of Aortic Dissection)
    James L Januzzi
    Thoracic Aorta Center and Cardiology Division, Massachusetts General Hospital, Boston, 02114, USA
    Am J Cardiol 94:400-2. 2004
    ..Our data support the importance of aneurysm surveillance and prophylactic surgical intervention for patients with Marfan's syndrome to potentially reduce the risk of mortality...
  82. ncbi Triggers and circadian distribution of the onset of acute aortic dissection
    Satoshi Kojima
    Department of Cardiology, Juntendo University Izunagaoka Hospital, Shizuoka, Japan
    Circ J 66:232-5. 2002
    ..3% vs 70.4%, p<0.0001). Most (86.6%) of the AAD episodes were related to physical or mental stress, particularly those that occurred during the day...
  83. ncbi Aortic dissection--in pursuit of a serum marker
    M Ayaz Mir
    Department of Medicine, Division of Hematology, University at Buffalo, Buffalo, NY 14212, USA
    Am J Emerg Med 26:942-5. 2008
    ..Other blood tests focus on myosin heavy chain and metalloproteinase release for the aortic media during dissection. The future seems promising...
  84. ncbi Initial experience with intentional stent-graft coverage of the subclavian artery during endovascular thoracic aortic repairs
    Johannes Görich
    Department of Radiology, University of Ulm, Germany
    J Endovasc Ther 9:II39-43. 2002
    ..To investigate the extent to which clinical status is affected by covering the left subclavian artery (LSA) with stent-grafts in the thoracic aorta...
  85. ncbi Clinical, diagnostic, and management perspectives of aortic dissection
    Ijaz A Khan
    Division of Cardiology, Department of Medicine, Creighton University School of Medicine, Omaha, NB, USA
    Chest 122:311-28. 2002
    ..The clinical, diagnostic, and management perspectives on aortic dissection and its variants, aortic intramural hematoma and atherosclerotic aortic ulcer, are reviewed...
  86. pmc A Gly1127Ser mutation in an EGF-like domain of the fibrillin-1 gene is a risk factor for ascending aortic aneurysm and dissection
    U Francke
    Howard Hughes Medical Institute, Stanford University Medical Center, CA, USA
    Am J Hum Genet 56:1287-96. 1995
    ..The Gly1127Ser mutation, therefore, produces a mild form of autosomal dominantly inherited weakness of elastic tissue, which predisposes to ascending aortic aneurysm and dissection later in life...
  87. ncbi Dissecting aneurysm confined to the anterior cerebral artery
    K Mori
    Department of Neurosurgery, Juntendo University, Izunagaoka Hospital, Shizuoka, Japan
    Br J Neurosurg 16:158-64. 2002
    b>Dissecting aneurysm confined to the anterior cerebral artery (ACA) is extremely rare...
  88. ncbi Value of plasma fibrin D-dimers for detection of acute aortic dissection
    Holger Eggebrecht
    Department of Cardiology, West German Heart Center Essen, University of Duisburg Essen, Germany
    J Am Coll Cardiol 44:804-9. 2004
    ..The purpose of this research was to assess the value of systemic inflammatory biomarkers in the detection of acute aortic dissection (AD)...
  89. ncbi Aortic root replacement in 271 Marfan patients: a 24-year experience
    Vincent L Gott
    Division of Cardiac Surgery, the Institute of Genetic Medicine and the Howard Hughes Medical Institute, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Ann Thorac Surg 73:438-43. 2002
    ..We performed our first Bentall composite graft procedure in 1976 and herein report our 24-year experience with 271 Marfan patients...
  90. ncbi Spontaneous dissection of the superior mesenteric artery diagnosed on multidetector helical CT
    Hiroyoshi Furukawa
    Department of Diagnostic Radiology, National Cancer Center Hospital, Tokyo, Japan
    J Comput Assist Tomogr 26:143-4. 2002
  91. ncbi Thoracic aortic stent-graft devices: problems, failure modes, and applicability
    Christoph A Nienaber
    Division of Cardiology, University Hospital Rostock, Rostock School of Medicine, Rostock, Germany
    Semin Vasc Surg 20:81-9. 2007
    ..The aim of this work is to give an overview on thoracic aortic stent-graft devices with focus on problems, failure modes and potential improvements...
  92. ncbi Randomized comparison of strategies for type B aortic dissection: the INvestigation of STEnt Grafts in Aortic Dissection (INSTEAD) trial
    Christoph A Nienaber
    Department of Internal Medicine, Division of Cardiology, University of Rostock, Ernst Heydemann Strasse 6, Rostock, Germany
    Circulation 120:2519-28. 2009
    ..Thoracic endovascular aortic repair (TEVAR) represents a novel concept for type B aortic dissection. Although life-saving in acute emergencies, outcomes and survival of TEVAR in stable dissection are unknown...
  93. pmc Myocardial infarction resulting from coronary artery dissection in an adolescent with Ehlers-Danlos syndrome type IV due to a type III collagen mutation
    L C Ades
    Department of Medical Genetics and Epidemiology, Women s and Children s Hospital, North Adelaide, Australia
    Br Heart J 74:112-6. 1995
    ..This patient represents the first case of type IV Ehlers-Danlos syndrome with symptomatic coronary artery dissection...
  94. ncbi Omental pedicle graft in the management of infected ascending aortic prostheses
    D W Miller
    Swedish Hospital Medical Center, Seattle, WA
    Ann Thorac Surg 44:614-7. 1987
    ..An omental graft was used to protect the vascular prosthesis and minimize the risk of recurrent infection...
  95. ncbi Choice of computed tomography, transesophageal echocardiography, magnetic resonance imaging, and aortography in acute aortic dissection: International Registry of Acute Aortic Dissection (IRAD)
    Andrew G Moore
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA
    Am J Cardiol 89:1235-8. 2002
  96. ncbi Outcome of surgical treatment in patients with acute type B aortic dissection
    Tomoki Shimokawa
    Department of Cardiovascular Surgery, Sakakibara Heart Institute, Tokyo, Japan
    Ann Thorac Surg 86:103-7. 2008
    ..Surgery for acute type B aortic dissection is associated with significant mortality and morbidity. The purpose of this study was to assess the clinical outcome of surgical management of complicated acute type B aortic dissection...
  97. ncbi Modular branched stent graft for endovascular repair of aortic arch aneurysm and dissection
    Timothy A M Chuter
    Division of Vascular Surgery, University of California San Francisco, 505 Parnassus Avenue, M 488, San Francisco, CA 94143, USA
    J Vasc Surg 38:859-63. 2003
    ..We describe a modular stent graft for use in endovascular repair of aneurysms of the aortic arch...
  98. ncbi Percutaneous intervention of spontaneous renal artery dissection complicated with renal infarction: a case report and literature review
    Sang Hak Lee
    Cardiology Division, Yonsei Cardiovascular Center and Cardiovascular Research Institute, Yonsei University College of Medicine, Seoul, South Korea
    Catheter Cardiovasc Interv 60:335-8. 2003
    ..We describe a 48-year-old male patient with SRAD complicated with renal infarction who was successfully treated with percutnaeous angioplasty and renal artery stenting...
  99. ncbi Results of endovascular repair of the thoracic aorta with the Talent Thoracic stent graft: the Talent Thoracic Retrospective Registry
    Rossella Fattori
    Cardiovascular Radiology, University Hospital S Orsola, Bologna, Italy
    J Thorac Cardiovasc Surg 132:332-9. 2006
    ..The Talent Thoracic Retrospective Registry was designed to evaluate the impact of this therapy on patients treated in 7 major European referral centers over an 8-year period...
  100. ncbi Isolated spontaneous dissection of the splanchnic arteries
    Toshio Takayama
    Division of Vascular Surgery, Department of Surgery, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    J Vasc Surg 48:329-33. 2008
    ..This study was conducted to define the characteristics of patients with splanchnic artery dissection and the clinical course of isolated splanchnic artery dissection...
  101. ncbi Endovascular repair of the thoracic aorta: lessons learned
    Frank J Criado
    Center for Vascular Intervention, Division of Vascular Surgery, Union Memorial Hospital, MedStar Health, Baltimore, Maryland, USA
    Ann Thorac Surg 80:857-63; discussion 863. 2005
    ..We sought to gain a better understanding of these issues through a retrospective review of our 8-year clinical experience in the treatment of thoracic aortic aneurysms and dissections...

Research Grants24

  1. Pathophysiology and Treatment of Pulmonary Hypertension
    Marc Moon; Fiscal Year: 2004
    ..abstract_text> ..
  2. Atomic Force Microscopic Studies of Dissecting Aneurysm
    Paul J Boor; Fiscal Year: 2013
    ..These combined in vivo, in vitro, biophysical and molecular approaches will identify the structural/molecular toxic effects of AEEA that weaken the aortic wall to result in DAA. ..
  3. 1999 GORDON CONFERENCE ON ELASTIN AND ELASTIN TISSUES
    Francesco Ramirez; Fiscal Year: 1999
    ..organ system and include complex pathologies like pulmonary hypertension and emphysema, atherosclerosis and dissecting aneurysm, and dermal, and dermal elastoses and progeria, as well as monogenic entities like Marfan syndrome, ..
  4. VOLUMETRIC ANALYSIS OF THE AORTA AND ITS BRANCHES
    Geoffrey Rubin; Fiscal Year: 2002
    ....
  5. Improving Radiologist Detection of Lung Nodules with CAD
    Geoffrey Rubin; Fiscal Year: 2008
    ..abstract_text> ..
  6. Genetic Basis of Aortic Aneurysms/Dissections
    Dianna Milewicz; Fiscal Year: 2009
    ..Therefore, identification of the genes that predispose individuals to TAAD is critical in preventing premature deaths due to dissections. ..
  7. CHARACTERIZING MICROFIBRIL ABNORMALITIES IN SCLERODERMA
    Dianna Milewicz; Fiscal Year: 2003
    ..The research proposed in this grant will determine the contribution of abnormalities in fibrillin-1-containing microfibrils to the activation of fibroblasts, which leads to the fibrosis that characterizes SSc. ..
  8. Vein wall remodeling after DVT is matrix metalloproteinase dependent
    Peter Henke; Fiscal Year: 2009
    ..This proposal will provide important mechanistic insight into the pathophysiology of post-phelbitic syndrome with real potential translation to decreasing the morbidity from this under-acknowledged disease. ..
  9. Myocardial regeneration in ischemic cardiomyopathy
    Marc Penn; Fiscal Year: 2009
    ....
  10. Osteoprotegerin and osteopontin in aortic aneurysm
    Jonathan Golledge; Fiscal Year: 2009
    ..Understanding the role of these calcium-controlling proteins in artery weakness and how drug therapy can interfere in these effects is an important step in the development of new treatment for aortic aneurysm. ..
  11. EXCITOTOXICITY IN CIRCULATORY ARREST--BRAIN INJURY
    William Baumgartner; Fiscal Year: 2007
    ....
  12. Iron and Atherosclerosis
    Subha Raman; Fiscal Year: 2006
    ..Subgroup analyses will include comparison of the presence of iron symptomatic versus asymptomatic patients and women versus age-matched men. ..
  13. EXTRACELLULAR MATRIX IN MICE LACKING THROMBOSPONDIN 2
    Paul Bornstein; Fiscal Year: 2006
    ..These experiments have the potential to develop the means to improve wound healing, and the performance of implanted biosensors and delivery devices, in human subjects. ..
  14. Thrombus resolution is CXC chemokine dependent
    Peter Henke; Fiscal Year: 2006
    ..abstract_text> ..
  15. New ECG Criteria for Posterior Myocardial Infarction
    Shu Fen Wung; Fiscal Year: 2004
    ..This study will aid in the detection and follow-up of patients with posterior myocardial infarction. ..
  16. GSTs: Oxidative Stress in Early Atherosclerosis
    Paul Boor; Fiscal Year: 2006
    ..abstract_text> ..
  17. MMP-9-Dependent Vessel Wall Remodeling is NO-Dependent
    Gilbert Upchurch; Fiscal Year: 2005
    ....
  18. ENDOTHELIAL DYSFUNCTION: FORMATION OF MICROPARTICLES
    Sergey Brodsky; Fiscal Year: 2005
    ..The proposed studies may provide novel information on the contribution of microparticles to the pathophysiology of endothelial cell dysfunction and coagulation abnormalities. ..
  19. VEIN GRAFT PRESERVATION: THROMBOSIS & NEOINTIMAL DISEASE
    Yoshifumi Naka; Fiscal Year: 2004
    ..The current proposal is driven by the applicant?s desire to use a model of vein graft disease as a tool to learn how to undertake basic studies to elucidate mechanisms of early and late vein graft failure...
  20. BIOGENESIS AND FUNCTION OF CONNECTIVE TISSUE PROTEINS
    Paul Bornstein; Fiscal Year: 2004
    ..It is anticipated that some of the mutations created in mice will generate useful models for human disorders of these tissues, specifically some of the Ehlers-Danlos syndromes and osteoporosis. ..
  21. Extracellular Mechanisms For Thoracic Aortic Aneurysms
    John Ikonomidis; Fiscal Year: 2008
    ..abstract_text> ..
  22. Fetal Basis of Dissecting Aortic Aneurysm
    Paul Boor; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  23. Homocysteine/Hypertension & Vascular Lesion Formation
    Peter Lin; Fiscal Year: 2008
    ..abstract_text> ..