ventricular outflow obstruction

Summary

Summary: Occlusion of the ventricular outflow or inflow tract on either side of the heart. It may result from a congenital defect or predisposing heart disease, or as a complication of surgery or tumors of the heart or its vessels.

Top Publications

  1. ncbi Long-term effects of surgical septal myectomy on survival in patients with obstructive hypertrophic cardiomyopathy
    Steve R Ommen
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Am Coll Cardiol 46:470-6. 2005
  2. ncbi Right ventricular function in adults with repaired tetralogy of Fallot assessed with cardiovascular magnetic resonance imaging: detrimental role of right ventricular outflow aneurysms or akinesia and adverse right-to-left ventricular interaction
    Periklis A Davlouros
    Department of Cardiology, Royal Brompton Hospital, London, United Kingdom
    J Am Coll Cardiol 40:2044-52. 2002
  3. ncbi Unexplained hypotension: the spectrum of dynamic left ventricular outflow tract obstruction in critical care settings
    Anand Chockalingam
    Department of Internal Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO, USA
    Crit Care Med 37:729-34. 2009
  4. ncbi Biventricular response after pulmonary valve replacement for right ventricular outflow tract dysfunction: is age a predictor of outcome?
    Alessandra Frigiola
    Cardiothoracic Unit, Great Ormond Street Hospital for Children, Great Ormond Street, London WC1N 3JH, UK
    Circulation 118:S182-90. 2008
  5. ncbi The V(2) transition ratio: a new electrocardiographic criterion for distinguishing left from right ventricular outflow tract tachycardia origin
    Brian P Betensky
    Section of Cardiac Electrophysiology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Am Coll Cardiol 57:2255-62. 2011
  6. ncbi American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European S
    Barry J Maron
    J Am Coll Cardiol 42:1687-713. 2003
  7. pmc Short- and medium-term outcomes after transcatheter pulmonary valve placement in the expanded multicenter US melody valve trial
    Doff B McElhinney
    Department of Cardiology, Children s Hospital Boston, Boston, Mass 10032, USA
    Circulation 122:507-16. 2010
  8. ncbi Dynamic left ventricular outflow tract obstruction secondary to catecholamine excess in a normal ventricle
    S Mingo
    Int J Cardiol 112:393-6. 2006
  9. ncbi Current strategy of repair of tetralogy of Fallot in children and adults: emphasis on a new technique to create a monocusp-patch for reconstruction of the right ventricular outflow tract
    Guo Wei He
    Medical College, Nankai University and TEDA International Cardiovascular Hospital, Tianjin, The Chinese University of Hong Kong, Hong Kong, China
    J Card Surg 23:592-9. 2008
  10. ncbi Preoperative thresholds for pulmonary valve replacement in patients with corrected tetralogy of Fallot using cardiovascular magnetic resonance
    Thomas Oosterhof
    Academic Medical Center, Department of Cardiology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Circulation 116:545-51. 2007

Detail Information

Publications203 found, 100 shown here

  1. ncbi Long-term effects of surgical septal myectomy on survival in patients with obstructive hypertrophic cardiomyopathy
    Steve R Ommen
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Am Coll Cardiol 46:470-6. 2005
    ..This study sought to determine the impact of surgical myectomy on long-term survival in hypertrophic cardiomyopathy (HCM)...
  2. ncbi Right ventricular function in adults with repaired tetralogy of Fallot assessed with cardiovascular magnetic resonance imaging: detrimental role of right ventricular outflow aneurysms or akinesia and adverse right-to-left ventricular interaction
    Periklis A Davlouros
    Department of Cardiology, Royal Brompton Hospital, London, United Kingdom
    J Am Coll Cardiol 40:2044-52. 2002
    ....
  3. ncbi Unexplained hypotension: the spectrum of dynamic left ventricular outflow tract obstruction in critical care settings
    Anand Chockalingam
    Department of Internal Medicine, Division of Cardiovascular Medicine, University of Missouri School of Medicine, Columbia, MO, USA
    Crit Care Med 37:729-34. 2009
    ..To illustrate the clinical and hemodynamic abnormalities caused by dynamic left ventricular outflow tract obstruction (LVOTO) in critical care setting...
  4. ncbi Biventricular response after pulmonary valve replacement for right ventricular outflow tract dysfunction: is age a predictor of outcome?
    Alessandra Frigiola
    Cardiothoracic Unit, Great Ormond Street Hospital for Children, Great Ormond Street, London WC1N 3JH, UK
    Circulation 118:S182-90. 2008
    ..We wanted to assess the determinants of improvement after PVR for pulmonary regurgitation over a wide range of patient ages and to use any identified predictors to compare clinical outcomes between patient groups...
  5. ncbi The V(2) transition ratio: a new electrocardiographic criterion for distinguishing left from right ventricular outflow tract tachycardia origin
    Brian P Betensky
    Section of Cardiac Electrophysiology, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Am Coll Cardiol 57:2255-62. 2011
    ....
  6. ncbi American College of Cardiology/European Society of Cardiology clinical expert consensus document on hypertrophic cardiomyopathy. A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents and the European S
    Barry J Maron
    J Am Coll Cardiol 42:1687-713. 2003
  7. pmc Short- and medium-term outcomes after transcatheter pulmonary valve placement in the expanded multicenter US melody valve trial
    Doff B McElhinney
    Department of Cardiology, Children s Hospital Boston, Boston, Mass 10032, USA
    Circulation 122:507-16. 2010
    ..The Melody valve was recently approved in the United States for placement in dysfunctional right ventricular outflow tract conduits...
  8. ncbi Dynamic left ventricular outflow tract obstruction secondary to catecholamine excess in a normal ventricle
    S Mingo
    Int J Cardiol 112:393-6. 2006
    ..We have met only one case reported in the literature matching those conditions. In order to treat this type of patients properly, it is essential to take in consideration this pathology...
  9. ncbi Current strategy of repair of tetralogy of Fallot in children and adults: emphasis on a new technique to create a monocusp-patch for reconstruction of the right ventricular outflow tract
    Guo Wei He
    Medical College, Nankai University and TEDA International Cardiovascular Hospital, Tianjin, The Chinese University of Hong Kong, Hong Kong, China
    J Card Surg 23:592-9. 2008
    ....
  10. ncbi Preoperative thresholds for pulmonary valve replacement in patients with corrected tetralogy of Fallot using cardiovascular magnetic resonance
    Thomas Oosterhof
    Academic Medical Center, Department of Cardiology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Circulation 116:545-51. 2007
    ..To facilitate the optimal timing of pulmonary valve replacement, we analyzed preoperative thresholds of right ventricular (RV) volumes above which no decrease or normalization of RV size takes place after surgery...
  11. pmc Unruptured aneurysm of the sinus of Valsalva presenting with right ventricular outflow obstruction
    Roy Thankachen
    Department of Cardiothoracic Surgery, Christian Medical College and Hospital, Vellore 632 004, India
    Tex Heart Inst J 30:152-4. 2003
    ..and upon investigation was found to have an unruptured sinus of Valsalva aneurysm causing right ventricular outflow obstruction; there was an associated subaortic ventricular septal defect...
  12. ncbi Expanded polytetrafluoroethylene valved conduit and patch with bulging sinuses in right ventricular outflow tract reconstruction
    Takako Miyazaki
    Department of Pediatric Cardiovascular Surgery, Children s Research Hospital, Kyoto Prefectural University of Medicine, Hirokoji, Kamigyo ku, Kyoto, Japan
    J Thorac Cardiovasc Surg 134:327-32. 2007
    ..We designed a fan-shaped expanded polytetrafluoroethylene valved conduit and patch with bulging sinuses that create vortex flow, making them more reliable over the long term...
  13. ncbi Role of transcoronary ablation of septal hypertrophy in patients with hypertrophic cardiomyopathy, New York Heart Association functional class III or IV, and outflow obstruction only under provocable conditions
    Frank H Gietzen
    Department of Internal Medicine and Cardiology, The Bielefeld Hospital, Academic Teaching Hospital of the University of Muenster, Bielefeld, Germany
    Circulation 106:454-9. 2002
    ..It remains a point of debate whether an outflow obstruction at rest is a necessary criterion for interventional therapy...
  14. ncbi Subaortic obstruction in univentricular heart: results using the double barrel Damus-Kaye Stansel operation
    Andrew C Fiore
    Divisions of Cardiothoracic Surgery, Cardinal Glennon Children s Hospital, St Louis University School of Medicine, St Louis, MO, USA
    Eur J Cardiothorac Surg 35:141-6. 2009
    ..The purpose was to determine if PAB alters semilunar valve function after the double barrel DKS procedure and if this staged approach negatively influences the achievement of Fontan palliation...
  15. ncbi Effect of left ventricular outflow tract obstruction on clinical outcome in hypertrophic cardiomyopathy
    Martin S Maron
    Division of Cardiology, Tufts New England Medical Center, Boston, USA
    N Engl J Med 348:295-303. 2003
    ..The influence of left ventricular outflow tract obstruction on the clinical outcome of hypertrophic cardiomyopathy remains unresolved...
  16. ncbi Surgery insight: Septal myectomy for obstructive hypertrophic cardiomyopathy--the Mayo Clinic experience
    Joseph A Dearani
    Division of Cardiovascular Surgery, Mayo Clinic and Foundation, Rochester, MN 55905, USA
    Nat Clin Pract Cardiovasc Med 4:503-12. 2007
    ..These results should serve as a basis for comparison with newer nonsurgical treatment regimens...
  17. ncbi Valved bovine jugular vein conduits for right ventricular outflow tract reconstruction in children: an attractive alternative to pulmonary homograft
    John W Brown
    Section of Cardiothoracic Surgery, James W Riley Hospital for Children, Indiana University School of Medicine, Indianapolis, Indiana 46202 5123, USA
    Ann Thorac Surg 82:909-16. 2006
    ..Recently a valve-containing bovine jugular vein (Contegra, Medtronic, Inc, Minneapolis, MN) was introduced for clinical trials for a variety of patients requiring RVOT reconstruction...
  18. ncbi Long-term outcome of alcohol septal ablation in patients with obstructive hypertrophic cardiomyopathy: a word of caution
    Folkert J ten Cate
    Departments of Cardiology and Cardiothoracic Surgery, The Thoraxcenter, Erasmus Medical Center, s Gravendijkwal 230, Rotterdam, The Netherlands
    Circ Heart Fail 3:362-9. 2010
    ..The impact of alcohol septal ablation (ASA)-induced scar is not known. This study sought to examine the long-term outcome of ASA among patients with obstructive hypertrophic cardiomyopathy...
  19. pmc Dynamic left ventricular outflow tract obstruction without basal septal hypertrophy, caused by catecholamine therapy and volume depletion
    Ji Hyun Yang
    Department of Internal Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea
    Korean J Intern Med 23:106-9. 2008
    ..The solution for this is early recognition and correction of aggravating factors such as, withdrawal of catecholamine therapy and volume replacement...
  20. ncbi Double-chambered right ventricle presenting in adulthood
    D B McElhinney
    Division of Cardiothoracic Surgery, University of California, San Francisco, USA
    Ann Thorac Surg 70:124-7. 2000
    ..This lesion typically presents in childhood or adolescence and is often accompanied by a ventricular septal defect. Only a handful of previous cases have been described in which double-chambered right ventricle occurred in adulthood...
  21. ncbi Anteroapical stunning and left ventricular outflow tract obstruction
    R P Villareal
    Department of Cardiology, Texas Heart Institute/St Luke's Episcopal Hospital, 6624 Fannin, Suite 2480, Houston, TX 77030, USA
    Mayo Clin Proc 76:79-83. 2001
    ..The importance of this observation is that routine treatment of cardiogenic shock cannot be used and that conservative management results in excellent prognosis...
  22. ncbi Mitral valve abnormalities identified by cardiovascular magnetic resonance represent a primary phenotypic expression of hypertrophic cardiomyopathy
    Martin S Maron
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts Medical Center, No 70, 800 Washington St, Boston, MA 02111, USA
    Circulation 124:40-7. 2011
    ..Therefore, we applied cardiovascular magnetic resonance to characterize mitral valve morphology in a large HCM cohort...
  23. ncbi Controversies in cardiovascular medicine. Hypertrophic obstructive cardiomyopathy: alcohol septal ablation
    Michael A Fifer
    Cardiology Division, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    Eur Heart J 32:1059-64. 2011
    ..Non-randomized comparisons of septal ablation and septal myectomy have shown similar mortality rates and post-procedure New York Heart Association class for the two procedures...
  24. ncbi Prevalence, clinical significance, and natural history of left ventricular apical aneurysms in hypertrophic cardiomyopathy
    Martin S Maron
    Division of Cardiology, Hypertrophic Cardiomyopathy Center, Tufts Medical Center, Boston, Massachussetts 02111, USA
    Circulation 118:1541-9. 2008
    ..This study reports the prevalence, morphology, clinical course, and management of an underrecognized subgroup of HCM patients with left ventricular apical aneurysms...
  25. ncbi Controversies in cardiovascular medicine. Benefits of surgery in obstructive hypertrophic cardiomyopathy: bring septal myectomy back for European patients
    Barry J Maron
    Hypertrophic Cardiomyopathy Center, Minneapolis Heart Institute Foundation, 920 E 28th Street, Minneapolis, MN 55407, USA
    Eur Heart J 32:1055-8. 2011
    ..It is our aspiration that this discussion will generate reconsideration and resurgence of interest in surgical septal myectomy as a treatment option for severely symptomatic obstructive HCM patients within Europe...
  26. ncbi Left ventricular outflow obstruction in rhabdomyoma of infancy: meta-analysis of the literature
    Henri A Verhaaren
    Departments of Pediatrics and Cardiac Surgery, University and University Hospital of Ghent, De Pintelaan 185, B 9000 Ghent, Belgium
    J Pediatr 143:258-63. 2003
    ..Recently, severe obstruction of the left ventricular outflow tract by a solitary tumor was diagnosed during pregnancy and emergency surgery was needed soon after birth...
  27. ncbi One hundred pulmonary valve replacements in children after relief of right ventricular outflow tract obstruction
    Kirk R Kanter
    Department of Surgery, and the Sibley Heart Center, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Ann Thorac Surg 73:1801-6; discussion 1806-7. 2002
    ..We reviewed our experience with PVR late after RVOT reconstruction...
  28. ncbi Case 1. Right ventricular outflow obstruction caused by metastatic hepatocellular carcinoma
    Tzu Yu Lin
    Department of Anesthesis and Surgery, Far Eastern Memorial Hospital, Taipei, Taiwan
    J Clin Oncol 22:1152-3. 2004
  29. pmc Apical ballooning syndrome complicated by acute severe mitral regurgitation with left ventricular outflow obstruction--case report
    Manju D Chandrasegaram
    Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, Australia
    J Cardiothorac Surg 2:14. 2007
    ..The syndrome mimicks an acute myocardial infarction but is characterised by the absence of obstructive coronary disease. We describe a serious and poorly understood complication of Takotsubo cardiomyopathy...
  30. ncbi Effects of pulmonary valve replacement on QRS duration and right ventricular cavity size late after repair of right ventricular outflow tract obstruction
    Abdul R Doughan
    Adult Congenital Cardiac Program, Emory University Hospital School of Medicine, Atlanta, Georgia 30303, USA
    Am J Cardiol 95:1511-4. 2005
    ..93, p <0.0001) as well as after (r = 0.82, p <0.001) PVR. In patients with pulmonary regurgitation late after repair of RV outflow tract obstruction, PVR reduces maximal QRS duration with a concomitant decrease in RV volumes...
  31. ncbi Determination of timing for reoperation in patients after right ventricular outflow reconstruction
    Shunji Kurotobi
    Department of Developmental Medicine Pediatrics, Osaka University Graduate School, Osaka, Japan
    Am J Cardiol 95:1344-50. 2005
    ..These findings suggest that excess RV wall stress contributes to impaired RV performance. The RV stress-RVEF relation may be useful in assessing RV function and in establishing a surgical indication...
  32. ncbi The prognostic importance of left ventricular outflow obstruction in hypertrophic cardiomyopathy varies in relation to the severity of symptoms
    Camillo Autore
    Divisione di Cardiologia, Universita di Roma La Sapienza, Ospedale Sant Andrea, Via Grottarossa 1035 1039, 00189 Rome, Italy
    J Am Coll Cardiol 45:1076-80. 2005
    ..The aim of this study was to investigate whether the prognostic importance of left ventricular (LV) outflow obstruction in hypertrophic cardiomyopathy (HCM) is influenced by other predictors of morbidity and mortality...
  33. ncbi The effect of dobutamine stress on left ventricular outflow tract gradients in hypertensive patients with basal septal hypertrophy
    Fatih Yalcin
    Baskent University School of Medicine, Department of Cardiology, Medical and Research Center, Adana, Turkey
    Angiology 55:295-301. 2004
    ..This suggests dynamic ventricular ejection by stress may contribute to hypertrophy of the basal segment, which is the closest part of septum to increased afterload...
  34. pmc Pulmonary valve endocarditis caused by right ventricular outflow obstruction in association with sinus of valsalva aneurysm: a case report
    Katsufumi Nishida
    Department of Medicine, John A Burns School of Medicine, University of Hawaii, Honolulu, HI, USA
    J Cardiothorac Surg 3:46. 2008
    ..We report the first case of a pulmonary valve nonbacterial thrombotic endocarditis caused by right ventricular outlflow tract (RVOT) obstruction in association with a large sinus of Valsalva aneurysm...
  35. ncbi Management of univentricular heart with systemic ventricular outflow obstruction by pulmonary artery banding and Damus-Kaye-Stansel operation
    Takuya Miura
    Department of Cardiovascular Surgery, Osaka Medical Center and Research Institute for Maternal and Child Health, Osaka, Japan
    Ann Thorac Surg 77:23-8. 2004
    ..To clarify the indication, the changes in the diameter of ventricular outflow tract and the feasibility of DKS operation before or with Fontan were investigated...
  36. ncbi Bovine valved venous xenografts for RVOT reconstruction: results after 71 implantations
    Thomas Breymann
    Department of Thoracic and Cardiovascular Surgery, Heart Center North Rhine Westfalia, Ruhr University of Bochum, Bad Oeynhausen, Germany
    Eur J Cardiothorac Surg 21:703-10; discussion 710. 2002
    ..Contegra, a bovine jugular vein graft, might be an interesting alternative to overcome these problems...
  37. ncbi Hypertrophic cardiomyopathy is predominantly a disease of left ventricular outflow tract obstruction
    Martin S Maron
    Hypertrophic Cardiomyopathy Center, Division of Cardiology, Tufts New England Medical Center, Boston, MA 02111, USA
    Circulation 114:2232-9. 2006
    ..We sought to prospectively define the prevalence, clinical profile, and significance of left ventricular (LV) outflow tract obstruction under resting conditions and with physiological exercise in a large HCM cohort...
  38. ncbi Long-term follow-up after percutaneous septal ablation in hypertrophic obstructive cardiomyopathy
    H Seggewiss
    Medizinische Klinik 1, Leopoldina Krankenhaus, Gustav Adolf Str 8, 97422, Schweinfurt, Germany
    Clin Res Cardiol 96:856-63. 2007
    ..The aim of this study was to evaluate the longterm follow-up results of percutaneous transluminal septal myocardial ablation (PTSMA) in a large patient cohort...
  39. ncbi One-year follow-up of percutaneous septal ablation for symptomatic hypertrophic obstructive cardiomyopathy in 312 patients: predictors of hemodynamic and clinical response
    L Faber
    Department of Cardiology, Heart and Diabetes Center NRW, Ruhr University Bochum, GeorgStr 11, 32545, Bad Oeynhausen, Germany
    Clin Res Cardiol 96:864-73. 2007
    ....
  40. ncbi Formation of a stenotic fibrotic membrane at the distal anastomosis of bovine jugular vein grafts (Contegra) after right ventricular outflow tract reconstruction
    Alexander Kadner
    Clinic for Cardiovascular Surgery, University Hospital, Zurich, Switzerland
    J Thorac Cardiovasc Surg 127:285-6. 2004
  41. ncbi The bovine jugular vein: a totally integrated valved conduit to repair the right ventricular outflow
    Thierry Carrel
    Clinic for Cardiovascular Surgery, University Hospital Berne, Switzerland
    J Heart Valve Dis 11:552-6. 2002
    ..An early experience with a totally integrated Contegra valved conduit derived from a bovine jugular vein is reported; this conduit has the advantage that there is no discontinuity between its lumen and the valve it incorporates...
  42. ncbi Sinus of valsalva aneurysm obstructing the right ventricular outflow tract
    Peter Rosenberger
    Department of Cardiac Surgery, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Anesth Analg 102:1660-1. 2006
  43. pmc Total relief of severe left ventricular outflow obstruction after spontaneous rupture of chordae tendineae in a patient with hypertrophic cardiomyopathy
    A Q Araujo
    Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Heart 91:e35. 2005
    ..This case report highlights the role of the mitral valve apparatus in the genesis of obstruction in HCM, further stimulating surgical techniques in which mitral repair can be the main procedure...
  44. ncbi Understanding left ventricular outflow obstruction: anatomoechocardiographic correlation
    Nilda Espinola-Zavaleta
    Department of Echocardiography in Outpatient Clinic, Instituto Nacional de Cardiologia Ignacio Chavez, Mexico City, Mexico
    Congenit Heart Dis 1:161-8. 2006
    ..Knowledge of the morphological details of each type of obstruction is the basis for correct interpretation of the diagnostic images and clinical decisions...
  45. ncbi Right ventricular outflow tract reconstruction using Contegra valved conduit: natural history and conduit performance under pressure
    Suhair O Shebani
    Paediatric Cardiac Unit, Paediatric Cardiology and Cardiac Surgery Department, Birmingham Children s Hospital, B46LT Birmingham, UK
    Eur J Cardiothorac Surg 29:397-405. 2006
    ..To assess the performance of the bovine Contegra valved conduit used for right ventricular (RV) outflow tract reconstruction, particularly in relation to post-operative RV pressure...
  46. ncbi Use of bovine jugular vein to reconstruct the right ventricular outflow tract: early results
    Younes Boudjemline
    Service de Cardiologie Pediatrique, Hopital Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
    J Thorac Cardiovasc Surg 126:490-7. 2003
    ..We evaluate early results of bovine jugular vein conduits in the pulmonary outflow...
  47. ncbi Right ventricular outflow tract reconstruction with contegra monocuspid transannular patch in tetralogy of Fallot
    Bruno Chiappini
    Department of Thoracic and Cardiovascular Surgery, St Luc Hospital, Universite Catholique de Louvain, Brussels, Belgium
    Ann Thorac Surg 83:185-7. 2007
    ..The objective of this study was to assess whether Contegra valved bovine conduit, implanted as monocuspid transannular patch, might be an interesting alternative to overcome these problems...
  48. ncbi Catecholamine therapy inducing dynamic left ventricular outflow tract obstruction
    J Auer
    Int J Cardiol 101:325-8. 2005
    ..Early detection and intensive efforts to reverse the underlying conditions, including cessation of catecholamine therapy and correction of hypovolemia are essential...
  49. ncbi Early results of valved bovine jugular vein conduit for right ventricular outflow tract reconstruction
    M Mert
    Istanbul University, Institute of Cardiology, Department of Cardiovascular Surgery, Instanbul, Turkey
    Int J Artif Organs 28:251-5. 2005
    ..RVOT reconstruction by means of a conduit is often necessary in the majority of these patients in the early years of life and there are several proposed conduits for this purpose...
  50. ncbi Early results of using the bovine jugular vein for right ventricular outflow reconstruction during the Ross procedure
    Hitendu Dave
    University Hospital Zurich, Zurich, Switzerland
    Heart Surg Forum 6:390-2. 2003
    ..To study the early function of the bovine jugular vein (BJV) when used for right ventricular outflow tract (RVOT) reconstruction during the Ross procedure...
  51. ncbi Safety of stress testing in patients with hypertrophic cardiomyopathy
    Jeanne K Drinko
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, 9000 Euclid Avenue, Cleveland, Ohio 44195, USA
    Am J Cardiol 93:1443-4, A12. 2004
    ..Two hundred sixty-three consecutive patients with hypertrophic cardiomyopathy underwent stress testing. Major complications occurred in 0.04% of patients and minor events occurred in 23%...
  52. ncbi New xenograft valved conduit (Contegra) for right ventricular outflow tract reconstruction
    Andrew C Chatzis
    Department of Paediatric and Congenital Heart Surgery, Onassis Cardiac Surgery Centre, Athens, Greece
    Heart Surg Forum 6:396-8. 2003
    ..In this study, we describe our experience with a glutaraldehyde-treated bovine jugular vein valved conduit (Contegra)...
  53. ncbi Left ventricular outflow tract obstruction and sudden death risk in patients with hypertrophic cardiomyopathy
    Perry M Elliott
    The Heart Hospital, University College London, 16 18 Westmoreland Street, London W1G 8PH, UK
    Eur Heart J 27:1933-41. 2006
    ..The influence of LVOTO on survival from SD in relation to other recognized clinical risk markers is unknown...
  54. ncbi Surgical versus alcohol septal ablation for hypertrophic obstructive cardiomyopathy: the pendulum swings
    Magdi H Yacoub
    Circulation 112:450-2. 2005
  55. ncbi Mitral systolic anterior motion (SAM) with dynamic left ventricular outflow obstruction following aortic valve replacement
    Edmund Kenneth Kerut
    Heart Clinic of Louisiana, Marrero, Louisiana, Departments of Physiology and Pharmacology, LSU Health Sciences Center, New Orleans, Louisiana, USA
    Echocardiography 24:658-60. 2007
  56. ncbi Percutaneous insertion of the pulmonary valve
    Philipp Bonhoeffer
    Cardiothoracic Unit, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom
    J Am Coll Cardiol 39:1664-9. 2002
    ..We report our experience of percutaneous valve insertion in pulmonary position in humans...
  57. ncbi Subvalvular left ventricular outflow obstruction for patients undergoing aortic valve replacement for aortic stenosis: echocardiographic recognition and identification of patients at risk
    David S Bach
    Division of Cardiology, Department of Medicine, The University of Michigan, Ann Arbor, Michigan 48109, USA
    J Am Soc Echocardiogr 18:1155-62. 2005
    ..Concomitant valvular and subvalvular left ventricular outflow obstruction was first hypothesized in 1957, and identified and further characterized in the 1960s, before the ..
  58. ncbi Obstruction of the right ventricular outflow tract caused by a tuberculoma in a patient with ventricular septal defect and aneurysm of the membranous septum
    C L Santos
    Heart Institute of Pernambuco, Recife, Brazil
    Cardiol Young 9:509-11. 1999
    ..The obstruction was discovered at surgery and the tuberculous aetiology was only demonstrated histologically. To the authors' knowledge, this is the first report of a tuberculoma of the heart associated with congenital heart disease...
  59. ncbi [Dynamic left ventricular obstruction associated with a pheochromocytoma reversible after tumor ablation]
    B Gallet
    Service de cardiologie, Centre Hospitalier Victor-Dupouy, 69, rue du Lieutenant-Colonel-Prudhon, 95107 Argenteuil
    Arch Mal Coeur Vaiss 94:1195-8. 2001
    ..The removal of the pheochromocytoma is usually followed by the complete regression of left intraventricular obstruction, as in this case...
  60. ncbi Early results of valved bovine jugular vein conduit versus bicuspid homograft for right ventricular outflow tract reconstruction
    Thierry Bove
    Cardiac Unit, Hopital Universitaire des Enfants Reine Fabiola, U L B V U B, Brussels, Belgium
    Ann Thorac Surg 74:536-41; discussion 541. 2002
    ..Recently, a valve-containing segment of bovine jugular vein (Contegra, Medtronic Inc, Minneapolis, MN) has been introduced as a potential alternative conduit...
  61. pmc Aspergillus endocarditis: a case of near complete left ventricular outflow obstruction
    Rizwan Q Attia
    Department of Cardiovascular Surgery, Guy s and St Thomas Hospital NHS Foundation Trust, London, UK
    Interact Cardiovasc Thorac Surg 14:894-6. 2012
    ..We discuss the clinical difficulties in managing patients with fungal infective endocarditis and present a brief review of cardiac aspergillosis management...
  62. ncbi Beneficial effect of dual-chamber pacing for a left mid-ventricular obstruction with apical aneurysm
    Hiroyuki Watanabe
    The 2nd Department of Internal Medicine, Akita University School of Medicine, Japan
    Circ J 66:981-4. 2002
    ..Such findings by continuous wave Doppler can be useful in pacing therapy for evaluating changes in the severity of mid-ventricular obstruction...
  63. ncbi Deep sternal wire infection resulting in severe pulmonary valve endocarditis
    Sekar S Bhavani
    Department of Thoracic and Cardiovascular Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Ann Thorac Surg 82:1111-3. 2006
    ....
  64. ncbi Adverse mid-term outcome following RVOT reconstruction using the Contegra valved bovine jugular vein
    Volkhard Göber
    Clinic for Cardiovascular Surgery, Berne, Switzerland
    Ann Thorac Surg 79:625-31. 2005
    ..was introduced as an alternative xenograft tissue for RVOT reconstruction. Promising early hemodynamic and clinical results have been reported so far, but still less is known about mid-term adverse outcome...
  65. ncbi The Contegra bovine valved jugular vein conduit for pediatric RVOT reconstruction: 4 years experience with 108 patients
    Thomas Breymann
    Department of Pediatric Cardiac Surgery, Hannover Medical University, Hannover, Germany
    J Card Surg 19:426-31. 2004
    ..The study gives the preliminary results from a controlled prospective multicenter trial aiming at FDA admission...
  66. ncbi Echocardiographic correlates of left ventricular outflow obstruction and systolic anterior motion following mitral valve repair
    P M Shah
    Hoag Heart Institute, Newport Beach, CA 92658-6100, USA
    J Heart Valve Dis 10:302-6. 2001
    BACKGROUND AND AIM OF THE STUDY: Systolic anterior motion (SAM) of the mitral valve resulting in left ventricular outflow obstruction is a well-recognized complication of repair of the degenerative myxomatous mitral valve...
  67. ncbi Corrected tetralogy of Fallot: delayed enhancement in right ventricular outflow tract
    Thomas Oosterhof
    Department of Radiology, Leiden University Medical Center, Leiden, The Netherlands
    Radiology 237:868-71. 2005
    ....
  68. ncbi Comparison of dual-chamber pacing with nonsurgical septal reduction effect in patients with hypertrophic obstructive cardiomyopathy
    P Petkow Dimitrow
    Institute of Cardiology, Collegium Medicum Jagiellonian University, Krakow, Poland
    Int J Cardiol 94:31-4. 2004
    ..The aim of the study was to compare the influence of dual-chamber pacing vs. nonsurgical septal reduction on hemodynamic and morphological parameters in patients with obstructive form of hypertrophic cardiomyopathy...
  69. ncbi Hypertrophic obstructive cardiomyopathy: mechanism of obstruction and response to therapy
    Danita M Yoerger
    Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, USA
    Rev Cardiovasc Med 4:199-215. 2003
    ....
  70. ncbi Septal myectomy, papillary muscle resection, and mitral valve replacement for hypertrophic obstructive cardiomyopathy: a case report
    Junichiro Takahashi
    Division of Cardiovascular Surgery, Aishin Memorial Hospital, Sapporo, Japan
    Ann Thorac Cardiovasc Surg 14:258-62. 2008
    ....
  71. ncbi [Percutaneous transluminal septal myocardial ablation: early results and long-term follow-up]
    Łukasz Tekieli
    Klinika Chorób Serca i Naczyń, Krakowski Szpital Specjalistyczny im Jana Pawła II, Uniwersytet Jagiellonski, Collegium Medicum, Krakow
    Przegl Lek 63:628-32. 2006
    ..The aim of our study was to analyze early results, complications and long-term follow-up in patients after PTSMA...
  72. ncbi Treating hypertrophic cardiomyopathy: two views
    Lisa Salberg
    J Am Coll Cardiol 46:2146; author reply 2146-7. 2005
  73. ncbi Mechanisms for recurrent left ventricular outflow tract obstruction after septal myectomy for obstructive hypertrophic cardiomyopathy
    Kenji Minakata
    Division of Cardiovascular Surgery, Mayo Clinic and Foundation, Rochester, Minnesota, USA
    Ann Thorac Surg 80:851-6. 2005
    ..However, in a few patients, left ventricular outflow tract obstruction may recur and require repeat myectomy. We reviewed this subset of patients to assess the mechanisms of recurrence...
  74. ncbi The prognostic impact of septal myectomy in obstructive hypertrophic cardiomyopathy
    Hugh Watkins
    J Am Coll Cardiol 46:477-9. 2005
  75. ncbi A case series of myectomy: a review of its current application as an adjunct procedure
    Gunaratnam Niranjan
    Department of Cardiothoracic Surgery, St George s Hospital, London, UK
    J Card Surg 23:391-3. 2008
    ..The primary conditions requiring treatment were subaortic membrane, hypertrophic obstructive cardiomyopathy with mitral valve regurgitation, and aortic stenosis...
  76. ncbi Obstruction of left ventricular outflow tract after mechanical mitral valve replacement
    Qingyu Wu
    Heart Center, First Hospital of Tsinghua University, Beijing, China
    Ann Thorac Surg 85:1789-91. 2008
    ..The patient had an uneventful postoperative recovery, and left ventricular outflow tract obstruction disappeared on postoperative transthoracic echocardiography...
  77. ncbi Successful alcohol septal ablation for late recurrence of left ventricular outflow tract obstruction after surgical myectomy in hypertrophic obstructive cardiomyopathy
    Fiona Tromp
    Department of Cardiology, University Hospital Ghent, Belgium
    Acta Cardiol 63:271-5. 2008
    ..Mitral valve regurgitation was significantly reduced. This case nicely illustrates the feasibility of percutaneous alcohol septal ablation for recurrent LVOT obstruction 10 years after myectomy...
  78. ncbi An unexpected unsuccessful weaning from cardiopulmonary bypass
    Gabriele Via
    Department of Cardiothoracic Anesthesia, 1st Service of Anesthesia and Intensive Care, Pavia, Italy
    J Cardiothorac Vasc Anesth 18:242-4. 2004
  79. ncbi Catheter-based septal ablation for symptomatic hypertrophic obstructive cardiomyopathy: follow-up results of the TASH-registry of the German Cardiac Society
    L Faber
    Kardiologische Klinik Herz und Diabeteszentrum NRW, Universitatsklinik der Ruhr Universitat Bochum, Georgstrasse 11, 32545 Bad Oeynhausen, Germany
    Z Kardiol 94:516-23. 2005
    ..An analysis of the acute results has already been published. We now report on the mid-term course (3-6 months) of 242 pts. registered through September 1999...
  80. doi Left ventricular outflow tract obstruction after mitral valve replacement
    Prabhat Tewari
    Department of Anaesthesia Trent Cardiac Centre, Nottingham University Hospital Trust, City Hospital Campus, Hucknall Road NG5 1PB, Nottinghamshire, United Kingdom
    Anesth Analg 106:65-6. 2008
  81. ncbi Utility of isoproterenol to provoke outflow tract gradients in patients with hypertrophic cardiomyopathy
    Ahmad Elesber
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota, USA
    Am J Cardiol 101:516-20. 2008
    ..In conclusion, cardiac catheterization with isoproterenol challenge may identify patients with HC who may benefit from septal reduction therapy for whom the initial noninvasive evaluation does not show severe obstruction...
  82. ncbi Risk factors for early death and reoperation following biventricular repair of pulmonary atresia with intact ventricular septum
    Jonah Odim
    Division of Cardiothoracic Surgery, Department of Surgery, David Geffen School of Medicine at UCLA, 10833 Le Conte Avenue, CHS 62 226B Los Angeles, CA 90095, USA
    Eur J Cardiothorac Surg 29:659-65. 2006
    ..Since a functional right ventricle is desirable when repairing pulmonary atresia with intact ventricular septum, we sought to determine the factors that portend a successful biventricular repair in these children...
  83. ncbi The Lecompte maneuver for relief of airway compression in absent pulmonary valve syndrome
    Lars Nolke
    Pediatric Heart Center, UCSF Children s Hospital, San Francisco, California, USA
    Ann Thorac Surg 81:1802-7. 2006
    ..Surgical mortality rates as high as 16% to 56% have been reported. Here, we describe the surgical results using the Lecompte maneuver, reduction pulmonary arterioplasty, and a valved right ventricle to pulmonary artery (RV-PA) conduit...
  84. ncbi The optimal procedure for the great arteries and left ventricular outflow tract obstruction. An anatomical study
    Mark Hazekamp
    Department of Cardiothoracic Surgery, Leiden University Medical Center, Leiden, The Netherlands
    Eur J Cardiothorac Surg 31:879-87. 2007
    ..To describe the optimal surgical strategy in heart specimens with transposition of the great arteries (TGA) and left ventricular outflow tract obstruction (LVOTO)...
  85. ncbi Evaluation of 188 consecutive homografts implanted in pulmonary position after 20 years
    Dietmar Boethig
    Department of Pediatric Cardiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany
    Eur J Cardiothorac Surg 32:133-42. 2007
    ..Their long-term durability is limited, and alternatives became available. We evaluate their long-term hemodynamic performance to permit comparisons with alternative devices...
  86. ncbi A case report of surgical septal myectomy of hypertrophic cardiomyopathy with concomitant left ventricular outflow tract and mid-ventricular obstructions
    Niyazi Guler
    Cardiovascular Surgery Clinic, Yuzuncu Yil University, 65200 Van, Turkey
    J Card Surg 21:591-3; discussion 593. 2006
    ..Control Doppler echocardiograms revealed no left ventricular outflow tract gradient, although mid-ventricular gradient was persistent. The good results were still present 18 months after the operation...
  87. ncbi Long-term results of the Konno procedure for complex left ventricular outflow tract obstruction
    Rakesh M Suri
    Division of Cardiovascular Surgery, Mayo Clinic College of Medicine, Rochester, Minn 55905, USA
    J Thorac Cardiovasc Surg 132:1064-71. 2006
    ..This study was undertaken to determine long-term clinical and echocardiographic outcomes after the Konno procedure...
  88. ncbi Alcohol septal ablation after failed surgical myectomy
    Dominique Joyal
    Division of Cardiology, Loyola University Medical Center, Maywood, Illinois 60153, USA
    Catheter Cardiovasc Interv 69:999-1002. 2007
    ....
  89. ncbi [Alcohol ablation of the interventricular septum in a patient with hypertrophic obstructive cardiomyopathy complicated by an increase in the pressure gradient in the left ventricular outflow tract. A case report]
    Wojciech Płazak
    Klinika Chorób Serca i Naczyń, Krakowski Szpital Specjalistyczny im Jana Pawła II, ul Pradnicka 80, 31 202 Krakow
    Kardiol Pol 64:989-93. 2006
    ..The patient underwent urgent surgery (myectomy), followed by the mitral valve replacement with a favourable outcome...
  90. ncbi Pressure gradient response after alcohol septal ablation in hypertrophic obstructive cardiomyopathy
    Josef Veselka
    Kardiol Pol 64:1161-2; author reply 1162. 2006
  91. ncbi Does myectomy convey survival benefit in hypertrophic cardiomyopathy?
    Anna Woo
    University of Toronto, Toronto, ON, Canada
    Heart Fail Clin 3:275-88. 2007
    ..They examine the outcomes of obstructive HCM in patients after surgical versus conservative therapy. In addition, they review the studies that have compared other techniques to surgery for the management of obstructive HCM...
  92. ncbi Surgical strategies and outcomes in patients with Shone complex: a retrospective review
    James D St Louis
    The Children s Medical Center at the Medical College of Georgia, Augusta, Georgia 30912 4040, USA
    Ann Thorac Surg 84:1357-62; discussion 1362-3. 2007
    ..The formulation of an appropriate operative strategy remains problematic. Surgical outcomes have generally been poor. This review examines operative strategies and mid-term outcomes...
  93. ncbi A patient with hypertrophic obstructive cardiomyopathy presenting with left ventricular apical ballooning syndrome
    Wissam A Jaber
    Division of Cardiovascular Disease, The Mayo Clinic, 200 First Street, S W, Rochester, MN 55905, USA
    J Invasive Cardiol 18:510-2. 2006
  94. ncbi Predominant, severe right ventricular outflow tract obstruction in hypertrophic cardiomyopathy
    R Krecki
    II Chair of Cardiology, Medical University of Lodz, Bieganski Hospital, Kniaziewicza 1 5, 91 347 Lodz, Poland
    Circulation 116:e551-3. 2007
  95. ncbi Current effectiveness and risks of isolated septal myectomy for hypertrophic obstructive cardiomyopathy
    Nicholas G Smedira
    Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Ann Thorac Surg 85:127-33. 2008
    ..However, it is being challenged by a less-invasive alternative: alcohol septal ablation. This study examined the clinical effectiveness and risks of isolated septal myectomy for HOCM...
  96. ncbi Double-chambered right ventricle in an adult with Noonan syndrome
    Anshul M Patel
    Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cardiol Rev 14:e16-20. 2006
    ..To the best of our knowledge, this is the first report of a double-chambered right ventricle in an adult patient with Noonan syndrome...
  97. ncbi Delayed systolic anterior motion after mitral valve repair
    Giuseppe Rescigno
    Cardiovascular Department, Ospedali Riuniti, Ancona, Italy
    J Heart Valve Dis 15:512-4. 2006
    ..Subsequently, mitral valve replacement was required. This case demonstrates the importance of the LV geometrical relationships that predispose to this complication...
  98. ncbi Hybrid pulmonary valve implantation: injection of a self-expanding tissue valve through the main pulmonary artery
    Sven Dittrich
    Department of Congenital Heart Disease, Albert Ludwigs University of Freiburg, Freiburg, Germany
    Ann Thorac Surg 85:632-4. 2008
    ..The stented valve was fixed with three single sutures to avoid embolization. The interventional result was well with full competence of the valve. The boy was discharged at day 4 after the procedure...
  99. ncbi Accessory mitral valve causing left ventricular outflow tract obstruction in an adult
    Masahiro Okada
    Department of Cardiovascular Surgery, National Hospital Organization, Okayama Medical Center, 1711 1 Tamasu, Okayama, Okayama 701 1192, Japan
    Gen Thorac Cardiovasc Surg 56:77-80. 2008
    ..Evaluations revealed that the left ventricular outflow tract obstruction was caused by the accessory mitral valve. The patient underwent a successful operation for removal of the accessory mitral valve...
  100. ncbi The role of echocardiography in mitral valve dysfunction after repair
    R L Quigley
    Cardiothoracic Division, Department of Surgery, Frankford Hospitals, Torresdale Campus, Jefferson Health System, Philadelphia, PA 19114, USA
    Minerva Cardioangiol 55:239-46. 2007
    ..Intraoperative TEE is extremely valuable in evaluating the competency of the mitral valve following repair. In fact the results of this modality have a predictive valve in determining long-term outcomes in these patients...
  101. ncbi Beyond extended myectomy for hypertrophic cardiomyopathy: the resection-plication-release (RPR) repair
    Sandhya K Balaram
    Division of Cardiothoracic Surgery, St Luke s Roosevelt Hospital Center, Columbia University, College of Physicians and Surgeons, New York, New York 10025, USA
    Ann Thorac Surg 80:217-23. 2005
    ..We sought to investigate the medium-term success of this three-step repair that addresses all aspects of complex HCM pathology...

Research Grants7

  1. MECHANISM OF VENTRICULAR OUTFLOW OBSTRUCTION IN IHSS
    Robert Levine; Fiscal Year: 1991
    ..The knowledge to be gained from these studies could help us tailor therapy for this complex and vexing clinical problem...
  2. US Prostate Cancer Detection with Dutasteride Pretreatment
    Ethan Halpern; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  3. Multidisciplinary Study of Right Ventricular Dysplasia
    Jeffrey Towbin; Fiscal Year: 2005
    ..This integrated research grant proposal offers a substantial prospect of expanding the fund of clinical knowledge regarding ARVD and of localizing the gene(s) responsible for this disorder. ..
  4. Pediatric Thin-Film TiNi Catheter-Based Heart Valve
    Daniel Levi; Fiscal Year: 2005
    ..Phase II studies will focus on accelerated wear testing, long-term in vivo animal testing, and manufacturing issues. ..
  5. Bridge to neonatal Fontan repair of single ventricle
    Mark Rodefeld; Fiscal Year: 2006
    ..abstract_text> ..
  6. Genetics of Congenital Left-sided Heart Defects
    Kim McBride; Fiscal Year: 2007
    ..The proposed studies will launch the applicant on an independent research career, providing a base on which to advance genetic analyses of CCVM with the aim to reduce their occurrence and provide new treatment opportunities. ..