Genomes and Genes
aortic valve insufficiency
Summary: Backflow of blood from the aorta into the left ventricle, owing to imperfect functioning of the aortic semilunar valve.
Publications234 found, 100 shown here
- Recommendations for evaluation of the severity of native valvular regurgitation with two-dimensional and Doppler echocardiographyWilliam A Zoghbi
J Am Soc Echocardiogr 16:777-802. 2003
- Evaluation of left ventricular dimensions and function in Marfan's syndrome without significant valvular regurgitationLilian J Meijboom
Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands
Am J Cardiol 95:795-7. 2005..Some involvement of the left ventricle may have been present in a small group of these patients. No patients, however, fulfilled the criteria for dilated cardiomyopathy...
- Congenital quadricuspid aortic valve: report of nine surgical casesGoichi Yotsumoto
Second Department of Surgery, Kagoshima University, Faculty of Medicine, Sakuragaoka, Kagoshima, Japan
Ann Thorac Cardiovasc Surg 9:134-7. 2003..Valve repair failed in one patient and was converted to valve replacement during the operation. All patients underwent successful aortic valve replacement (AVR)...
- Bicuspid aortic valve leaflet morphology in relation to aortic root morphology: a study of 300 patients undergoing open-heart surgeryVeronica Jackson
Cardiothoracic Surgery Unit at the Department of Molecular Medicine and Surgery at Karolinska Institutet and Karolinska University Hospital
Eur J Cardiothorac Surg 40:e118-24. 2011....
- Quadricuspid aortic valve plasty: is it worth it to repair as an alternative to substitution?Andrea Daprati
Department of Cardiovascular Disease, Cardiac Surgery Unit, IRCCS Centro Cardiologico Fondazione Monzino, Milano, Italy
Ann Thorac Surg 95:e7-8. 2013..1 according to Hurwits and Roberts classification) with a marked lack of coaptation that caused a severe aortic valve insufficiency. The patient underwent a repair of the defect with a tricuspidalization of the aortic valve, restoring ..
- Quadricuspid aortic valve: a rare etiology of aortic regurgitationO Godefroid
Cardiology Unit, Mont Godinne University Hospital, Avenue G Therasse 1, B 5530 Yvoir, Belgium
Eur J Echocardiogr 7:168-70. 2006..We report two unusual cases of this valvular pathology associated with a dilatation of the aortic root. The mechanism leading to this valve incompetence is incompletely understood and is discussed in regard to these cases...
- Cardiovascular changes in children with mucopolysaccharide disordersU R Mohan
Departments of Paediatric Cardiology and Paediatric Metabolic Medicine Willink Biochemical Genetics Unit, Royal Manchester Children s Hospital, Hospital Road, Pendelbury, Manchester, UK
Acta Paediatr 91:799-804. 2002..However, left ventricular hypertrophy, mitral valve abnormalities and type II MPS were not significant risk factors for death, with borderline significance for aortic valve abnormalities...
- Bicuspid aortic valve associated with aortic dilatation: a community-based studyVuyisile T Nkomo
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, MN 55905, USA
Arterioscler Thromb Vasc Biol 23:351-6. 2003..An independent association of BAV and aortic dilatation in a community-based study has not been demonstrated...
- Regression of left ventricular hypertrophy during 10 years after valve replacement for aortic stenosis is related to the preoperative risk profileOle Lund
Department of Thoracic and Cardiovascular Surgery, Aarhus University Hospital in Skejby, Aarhus, Denmark
Eur Heart J 24:1437-46. 2003..The potential for hypertrophy regression could therefore be related to the preoperative risk profile...
- Prevalence and clinical significance of incidental paraprosthetic valvar regurgitation: a prospective study using transoesophageal echocardiographyA Ionescu
University of Wales College of Medicine, Cardiff, UK
Heart 89:1316-21. 2003..To assess the prevalence, mechanisms, and significance of paraprosthetic regurgitation detected incidentally by transoesophageal echocardiography (TOE) in patients after heart valve replacement...
- Tricuspidation of quadricuspid aortic valve: case reportsHugues Jeanmart
Department of Cardiothoracic and Vascular Surgery, Universite Catholique de Louvain, Cliniques Universitaires Saint Luc, Brussels, Belgium
J Heart Valve Dis 16:148-50. 2007..After one year and six months' follow up, respectively, both patients presented with trivial aortic regurgitation and good mobility of the three leaflets...
- Percutaneous aortic valve replacement: resection before implantationRene Quaden
Department of Cardiovascular Surgery, School of Medicine, Christian Albrechts University of Kiel, Arnold Heller Strasse 7, D 24105 Kiel, Germany
Eur J Cardiothorac Surg 27:836-40. 2005..After transluminal endovascular implantation of a new valved stent, the aim of this study was to evaluate the feasibility of using a high-pressure water stream to endovascularly resect human calcified aortic valves...
- Quadricuspid aortic valve with ascending aortic aneurysm: report of a case and discussion of embryological mechanismsRobert R Attaran
Sarver Heart Center, University of Arizona, Tucson, AZ 85724, USA
Cardiovasc Pathol 18:49-52. 2009..We describe the case of a patient with a QAV associated with aortic aneurysm. Pertinent literature on the QAV is reviewed, and embryological factors that may contribute to its pathogenesis are discussed...
- Transcatheter aortic valve implantation for stenosed and regurgitant aortic valve bioprostheses CoreValve for failed bioprosthetic aortic valve replacementsMuhammed Z Khawaja
Sussex Cardiac Centre, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK
J Am Coll Cardiol 55:97-101. 2010..We present the first series of such patients with degenerative bioprosthetic stenosis or regurgitation successfully treated with CoreValve (Medtronic, Luxembourg) implantation...
- Effects of exercise training after open heart surgery on quality of life and exercise tolerance in patients with mitral regurgitation or aortic regurgitationKenji Ueshima
Iwate Medical University, Memorial Heart Center, Iwate 020 8505, Japan
Jpn Heart J 45:789-97. 2004..It is suggested that changes in subjective and social parameters contribute to an exercise training-related improvement in the QOL...
- Steps toward percutaneous aortic valve replacementYounes Boudjemline
Service de Cardiologie Pediatrique, Hopital Necker Enfants Malades, Paris, France
Circulation 105:775-8. 2002..Percutaneous pulmonary valve replacement has recently opened new perspectives on transcatheter replacement of cardiac valves. We report our experience of aortic valve replacement through a percutaneous technique in lambs...
- Aortic valve repair for quadricuspid aortic valve associated with aortic regurgitation and ascending aortic aneurysmKozo Naito
Department of Cardiovascular Surgery, Saga Prefectural Hospital, Koseikan, 1 12 9 Mizugae, Saga 840 8571, Japan
J Thorac Cardiovasc Surg 128:759-60. 2004
- Successful repair of a quadricuspid aortic valve illustrated by transoesophageal echocardiography, 64-slice multidetector computed tomography, and cardiac magnetic resonanceAnne Catherine Pouleur
Division of Cardiology, Department of Cardiovascular Diseases, Cliniques Universitaires St Luc, Universite Catholique de Louvain, Avenue Hippocrate 10 2806, B 1200 Woluwe St Lambert, Brussels, Belgium
Eur Heart J 28:2769. 2007
- Congenital quadricuspid aortic valve: analysis of 11 surgical casesYang feng Tang
Department of Cardiothoracic Surgery, Changhai Hospital of the Second Military Medical University, Shanghai 200433, China
Chin Med J (Engl) 124:2779-81. 2011..Congenital quadricuspid aortic valve is rarely seen during aortic valve replacement (AVR). The diagnosis and treatment of the disease were reported in 11 cases...
- Images in cardiovascular medicine. A quadricuspid aortic valve with severe aortic regurgitationMichèle Desruennes
Clinique La Francilienne, Pontault Combault, France
Circulation 114:e642-3. 2006
- Percutaneous implantation of the CoreValve self-expanding valve prosthesis in high-risk patients with aortic valve disease: the Siegburg first-in-man studyEberhard Grube
Department of Cardiology Angiology, HELIOS Heart Center Siegburg, Ringstrasse 49, 53721 Siegburg, Germany
Circulation 114:1616-24. 2006....
- Quadricuspid aortic valve in a patient with mitral valve prolapseMehmet Fatih Ozlu
Department of Cardiology, Yuksek Ihtisas Hospital, Ankara, Turkey
Can J Cardiol 24:e27. 2008
- Left ventricular function in the Marfan syndrome without significant valvular regurgitationRitu Chatrath
Division of Pediatric Cardiology, Department of Medical Genetics, Mayo Clinic, Rochester, Minnesota 55905, USA
Am J Cardiol 91:914-6. 2003
- Multiple intracardiac lesions after blunt chest traumaA Aris
Department of Cardiac Surgery, Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
Ann Thorac Surg 70:1692-4. 2000..He underwent surgical repair of these lesions, but aortic insufficiency developed 2 years later and the aortic valve was replaced with a mechanical prosthesis...
- Cardiology patient pages. Aortic valve diseaseRick A Nishimura
Mayo Clinic and Mayo Foundation, Rochester, Minn 55905, USA rnishimura mayo edu
Circulation 106:770-2. 2002
- Reoperation after the Ross procedure: incidence, management, and survivalFrancis Juthier
Department of Cardiovascular Surgery, Centre Hospitalier Regional et Universitaire de Lille, Lille, France
Ann Thorac Surg 93:598-604; discussion 605. 2012..The risk of reoperation on the autograft and homograft is the major long-term drawback of the Ross procedure. The incidence and clinical implications of reoperations after the Ross procedure are reported...
- Prevalence and associated risk factors for intervention in 313 children with subaortic stenosisTara Karamlou
Division of Cardiovascular Surgery, University of Toronto, The Hospital for Sick Children, Toronto, Ontario, Canada
Ann Thorac Surg 84:900-6; discussion 906. 2007....
- Impact of prosthesis-patient mismatch on long-term survival in patients with small St Jude Medical mechanical prostheses in the aortic positionDania Mohty
Division of Cardiovascular Diseases, Mayo Clinic, Rochester, MN 55905, USA
Circulation 113:420-6. 2006..The impact of aortic prosthesis-patient mismatch (P-PtM) on long-term survival is unclear...
- Preliminary results following reinforcement of the pulmonary autograft to prevent dilatation after the Ross procedureThierry Carrel
Clinic for Cardiovascular Surgery, University Hospital, University Berne, Berne, Switzerland
J Thorac Cardiovasc Surg 136:472-5. 2008..We present our early experience with an external reinforcement of the autograft, which is inserted into a prosthetic Dacron graft with an artificial aortic root configuration. This detail should help to prevent neoaortic root dilatation...
- Transesophageal echocardiographic scoring for transcatheter aortic valve implantation: impact of aortic cusp calcification on postoperative aortic regurgitationAndrea Colli
Department of Cardiac Surgery, Hospital Universitari Germans Trias i Pujol, Badalona, Barcelona, Spain
J Thorac Cardiovasc Surg 142:1229-35. 2011..The aim of this study was to evaluate whether echocardiographic assessment of aortic stenosis using a calcification score is useful to predict outcomes of transcatheter aortic valve implantation in elderly high-risk patients...
- Ross and Ross-Konno procedure in children and adolescents: mid-term resultsV Hraska
Department of Pediatric Cardiac Surgery, University Hospital Hamburg Eppendorf, Martinistrase 52, 20246 Hamburg, Germany
Eur J Cardiothorac Surg 25:742-7. 2004..The aim of the study was to analyze mid-term results of aortic root replacement with pulmonary autograft in children and adolescents in two centers...
- Left ventricular remodeling with intensive exercise after aortic valve replacementAxel Pressler
Department for Prevention and Sports Medicine, Technische Universitat Munchen, Munich, Germany
J Heart Valve Dis 20:91-3. 2011..These findings indicate that even intensive endurance training after AVR seems to be feasible and safe, and may have a beneficial effect on postoperative cardiac remodeling...
- Dilatation of the pulmonary autograft and native aorta after the Ross procedure: a comprehensive echocardiographic studyObaid Aljassim
Department of Cardiovascular Surgery and Anesthesia, Sahlgrenska University Hospital, Gothenburg, Sweden
J Thorac Cardiovasc Surg 142:634-40, 640.e1. 2011..Whether the remaining native aorta dilates is not known. The aim of the study was to describe the prevalence and severity of autograft and native aortic dilatation over time and to identify possible determinants...
- The Ross procedure in children: preoperative haemodynamic manifestation has significant effect on late autograft re-operationBahaaldin Alsoufi
King Faisal Heart Institute, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
Eur J Cardiothorac Surg 38:547-55. 2010..We examined whether preoperative haemodynamic manifestation (e.g., stenosis, regurgitation and mixed aortic valve disease) affected late re-operation risk...
- Measurement of physical work capacity in patients with chronic aortic regurgitation: a potential improvement in patient managementEva Tamás
Department of Cardiothoracic Surgery, Ostergötland Heart Centre, University Hospital and Department of Medical and Health Sciences, University of Linkoping, Linkoping, Sweden
Clin Physiol Funct Imaging 29:453-7. 2009..Exercise testing is recommended upon uncertainty about functional limitations but reports on cardiopulmonary exercise testing (CPET) in populations with pure chronic AR are scarce...
- The role of cardiopulmonary exercise test in mitral and aortic regurgitation: it can predict post-operative resultsHyun Joong Kim
Division of Cardiovascular Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon Dong, Kangnam Ku, Seoul 135 170, Korea
Korean J Intern Med 18:35-9. 2003..We evaluated the efficacy of the cardiopulmonary exercise test as an objective indicator of functional status and as a pre-operative prognostic indicator in patients with mitral regurgitation (MR) and aortic regurgitation (AR)...
- Ross operation in children: late resultsR C Elkins
Section of Thoracic and Cardiovascular Surgery, University of Oklahoma Health Sciences Center, Oklahoma City 73190, USA
J Heart Valve Dis 10:736-41. 2001..CONCLUSION: Survival and freedom from aortic valve replacement are excellent in children. Homograft valve late function remains a concern, and efforts to improve homograft durability should be encouraged...
- Acute aortic valve insufficiency and cardiogenic shock due to an isolated giant cell inflammation of the aortic valve leaflets: case report and review of the literatureLars Niclauss
Department of Cardiovascular Surgery, University Hospital CHUV, Lausanne, Switzerland
J Heart Valve Dis 17:343-7. 2008..institution with acute cardiac failure, severe left ventricular systolic dysfunction and grade III aortic valve insufficiency. The aortic valve was excised and replaced in the usual manner with a pericardial tissue heart valve...
- Long-term results of a strategy of aortic valve repair in the pediatric populationYves d'Udekem
Department of Cardiac Surgery, Royal Children s Hospital, Flemington Rd, Parkville, Melbourne 3052, Victoria, Australia
J Thorac Cardiovasc Surg 145:461-7; discussion 467-9. 2013..To determine rate of reoperation subsequent to primary valve repair in a pediatric population...
- Multiple floppy valves with all cardiac valves prolapsing: clinical course and treatmentK Suzuki
Department of Pediatric Cardiology, Sakakibara Heart Institute, Tokyo, Japan
Pediatr Cardiol 12:110-3. 1991..None of the patients had any stigmata of Marfan or Ehlers-Danlos syndrome, except for the presence of hyperextensive joints. There may be an unknown collagen disorder that caused floppiness in all the valves...
- The Ross operation in children and young adults: a fifteen-year, single-institution experienceJoseph B Clark
Department of Pediatrics, Penn State Hershey, Hershey, Pennsylvania 17033, USA
Ann Thorac Surg 91:1936-41; discussion 1941-2. 2011..The goal of this study is to report our experience with the Ross operation and the need for reintervention at intermediate follow-up...
- Surgical treatment of subaortic obstruction in adolescent and adults: long-term follow-upVedat Erentug
Department of Cardiovascular Surgery, Kosuyolu Heart and Research Hospital, Istanbul, Turkey
J Card Surg 20:16-21. 2005....
- Major adverse cardiac and cerebrovascular events after the Ross procedure: a report from the German-Dutch Ross RegistryHans H Sievers
University of Luebeck, Department of Cardiac and Thoracic Vascular Surgery, Luebeck, Germany
Circulation 122:S216-23. 2010..These data could provide an additional basis for discussions among physicians and a source of information for patients...
- Exercise performance in children and adolescents after the Ross procedureBradley S Marino
Division of Cardiology, at the Cardiac Center of The Children s Hospital of Philadelphia, and the Department of Pediatrics at the University of Pennsylvania School of Medicine 19104, USA
Cardiol Young 16:40-7. 2006..The Ross procedure is increasingly utilized in the treatment of aortic valvar disease in children and adolescents. Our purpose was to compare pre- and post-operative exercise state in this population...
- ACC/AHA 2006 guidelines for the management of patients with valvular heart disease: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (writing committee to revise the 1998 Guidelines for the ManageRobert O Bonow
Circulation 114:e84-231. 2006
- Hemodynamics and early performance of the St. Jude Medical Regent aortic valve prosthesisD S Bach
The Department of Medicine, University of Michigan, Ann Arbor 48109, USA
J Heart Valve Dis 10:436-42. 2001..In all cases of adverse events, rates fell within Objective Performance Criteria guidelines. Long-term clinical assessment is on-going...
- Is aortic wall degeneration related to bicuspid aortic valve anatomy in patients with valvular disease?Claudio F Russo
Angelo De Gasperis Department of Cardiac Surgery, Niguarda Ca Granda Hospital, Piazza Ospedale Maggiore, Milan, Italy
J Thorac Cardiovasc Surg 136:937-42. 2008..Patients with bicuspid aortic valve are at increased risk for aortic complications...
- Aortic valve replacement in patients with impaired ventricular functionRam Sharony
Division of Cardiothoracic Surgery, Department of Surgery, New York University School of Medicine, New York, New York, USA
Ann Thorac Surg 75:1808-14. 2003..Patients with reduced ventricular function undergoing aortic valve replacement have increased operative risks, but the impact of valvular pathophysiology and other risk factors has not been clearly defined...
- The relationship between neo-aortic root dilation, insufficiency, and reintervention following the Ross procedure in infants, children, and young adultsSara K Pasquali
Division of Cardiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
J Am Coll Cardiol 49:1806-12. 2007..The purpose of this study was to describe the relationship between neo-aortic root size, neo-aortic insufficiency (AI), and reintervention at mid-term follow-up...
- Surgical management of aortic regurgitation associated with takayasu arteritis and other forms of aortitisOsamu Adachi
Department of Cardiovascular Surgery, Tohoku University Graduate School of Medicine, Sendai, Japan
Ann Thorac Surg 84:1950-3. 2007..Postoperative morbidity includes progressive dilatation of the aortic root. We sought to assess our midterm and long-term results of surgical management of aortic regurgitation associated with aortitis...
- Traumatic aortic regurgitation: aortic valvuloplasty controlled by aortoscopyJ P Meunier
Department of Cardiac Surgery, Pasteur Hospital, University of Nice, France
J Heart Valve Dis 10:784-8. 2001..Replacement is the safest treatment for complex or multiple injuries of the aortic valve, however...
- Effect of valve suture technique on incidence of paraprosthetic regurgitation and 10-year survivalSukumaran K Nair
Department of Cardiothoracic Surgery, St George s Hospital NHS Trust, London, United Kingdom
Ann Thorac Surg 89:1171-9. 2010..The secondary objective was to estimate the risk of redo valve surgery and 10-year survival after valve replacement performed using either suture technique...
- One year hemodynamic performance of the Perimount Magna pericardial xenograft and the Medtronic Mosaic bioprosthesis in the aortic position: a prospective randomized studyMaría José Dalmau
Department of Cardiac Surgery, Salamanca University Hospital, Paseo de San Vicente 58 182, 37007 Salamanca, Spain
Interact Cardiovasc Thorac Surg 6:345-9. 2007..8% (MM) vs. 6.9% (EPM) of the patients (P=0.01). When the same AAD is taken as a reference, the EPM-valve was hemodynamically superior to the MM-bioprosthesis. The EPM-prosthesis significantly reduced the incidence of PPM...
- Serial echocardiographic and clinical evaluation of valvular regurgitation before, during, and after treatment with fenfluramine or dexfenfluramine and mazindol or phentermineD H Ryan
Pennington Biomedical Research Center, Baton Rouge, LA 70808 4124, USA
Obes Res 7:313-22. 1999..We studied 86 patients who had echocardiograms before treatment with appetite suppressants to determine the incidence of new cases and to evaluate the clinical implication of the echocardiographic findings...
- Surgical treatment of aortic regurgitation due to Takayasu arteritis: long-term morbidity and mortalityKaoru Matsuura
Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Osaka, Japan
Circulation 112:3707-12. 2005..The goal of this retrospective study was to determine the late outcome of surgical treatment for aortic valve regurgitation due to Takayasu arteritis and correlate it with evidence of inflammation on pathological examination...
- Evaluation of aortic valve disorders using stress echocardiographyWen Chih Wu
Division of Cardiology, Providence VA Medical Center, and The Miriam Hospital, Brown Medical School, Providence, Rhode Island 02908, USA
Echocardiography 21:459-66. 2004....
- Risk factor analysis for proximal and distal reoperations after surgery for acute type A aortic dissectionMatthias Kirsch
Service de Chirurgie Thoracique et Cardiovasculaire, Hopital Henri Mondor, Creteil, France
J Thorac Cardiovasc Surg 123:318-25. 2002..This study was undertaken to determine significant risk factors for proximal or distal reoperations after surgical correction of acute type A aortic dissection...
- Aortic valve sclerosis is associated with systemic endothelial dysfunctionElisa Poggianti
Echocardiography Laboratory, Institute of Clinical Physiology, CNR, Pisa, Italy
J Am Coll Cardiol 41:136-41. 2003..We sought to examine the association between aortic valve sclerosis (AVS) and systemic endothelial manifestations of the atherosclerotic process...
- Is prosthesis-patient mismatch a clinically relevant entity?Tirone E David
Circulation 111:3186-7. 2005
- Valvular heart disease: aortic regurgitationRaffi Bekeredjian
Department of Cardiology, University of Heidelberg, Heidelberg, Germany
Circulation 112:125-34. 2005..The goal of vasodilator therapy is to achieve a significant decrease in systolic arterial pressure. Future therapies may focus on molecular mechanisms to prevent adverse LV remodeling and fibrosis...
- 64-slice multidetector computed tomography (MDCT) for detection of aortic regurgitation and quantification of severityDavinder S Jassal
Department of Medicine, Cardiology Division, Massachusetts General Hospital, Boston, Massachusetts, and the Department of Radiology, Indiana University School of Medicine, Indianapolis, Indiana, USA
Invest Radiol 42:507-12. 2007..Recent advances in 64-slice multidetector computed tomography (MDCT) provide an opportunity to assess coronary artery disease, left ventricular function and, potentially, valvular heart disease...
- Echocardiographic and histological assessment of age-related valvular changes in normal ratsSteven Droogmans
Department of Cardiology, UZ Brussel, Laarbeeklaan 101, Brussels, Belgium
Ultrasound Med Biol 35:558-65. 2009..In conclusion, aging leads to morphologic and functional valvular changes in normal rats. This is important when investigating models of valvular heart disease in small animals...
- Aortic valves stenosis and regurgitation: assessment with dual source computed tomographyXiaofei Li
Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China
Int J Cardiovasc Imaging 25:591-600. 2009..DSCT can achieve an exhaustive and comprehensive preoperative assessment of patients with AS and AR...
- Qualitative echocardiographic assessment of aortic valve regurgitation with quantitative cardiac magnetic resonance: a comparative studyShelby Kutty
University of Nebraska Creighton University Joint Division of Pediatric Cardiology, Children s Hospital and Medical Center, Omaha, NE 68114, USA
Pediatr Cardiol 30:971-7. 2009..Quantitative CMR is a potentially useful supplement to ECHO for management decisions and assessments of medical and surgical therapies in children and young adults with AR...
- Comprehensive assessment of the severity and mechanism of aortic regurgitation using multidetector CT and MRCéline Goffinet
Cardiology Division, Cliniques Universitaires St Luc UCL, Av Hippocrate 10 2806, 1200, Woluwe St Lambert, Belgium
Eur Radiol 20:326-36. 2010..Measurement of ARO by both MDCT and MR allows accurate quantitative assessment of AR. Both techniques can also accurately determine the mechanism of AR...
- Aortic regurgitation: assessment with 64-section CTHatem Alkadhi
Institute of Diagnostic Radiology, Clinic for Cardiovascular Surgery, and Cardiovascular Center, University Hospital Zurich, Raemistrasse 100, CH 8091 Zurich, Switzerland
Radiology 245:111-21. 2007..To prospectively evaluate diagnostic accuracy of 64-section computed tomography (CT) for evaluation of aortic regurgitation (AR), with transthoracic echocardiography (TTE) as reference...
- Clinical practice. Aortic regurgitationMaurice Enriquez-Sarano
Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic and Mayo Foundation, Rochester, Minn 55905, USA
N Engl J Med 351:1539-46. 2004
- Effectiveness of beta-blockade in experimental chronic aortic regurgitationEric Plante
Groupe de Recherche sur les Valvulopathies, Centre de recherche Hopital Laval, Institut de Cardiologie de Quebec, Universite Laval, Quebec, Canada
Circulation 110:1477-83. 2004..We therefore tested the effects of metoprolol treatment on the left ventricular (LV) function and remodeling in severe chronic AR in rats...
- Hemodynamic evaluation of aortic regurgitation by magnetic resonance imagingThomas Wittlinger
Department of Thoracic and Cardiovascular Surgery, University Hospital, Theodor Stern Kai 7, 60590 Frankfurt, Germany
Asian Cardiovasc Thorac Ann 16:278-83. 2008....
- Long-term vasodilator therapy in patients with severe aortic regurgitationArtur Evangelista
Servei de Cardiologia, Hospital Universitari Vall d Hebron, Barcelona, Spain
N Engl J Med 353:1342-9. 2005..Accordingly, it has been suggested that such therapy may reduce or delay the need for aortic-valve replacement...
- Surgical strategy for the bicuspid aortic valve: tricuspidization with cusp extension versus pulmonary autograftDavid Michael McMullan
Cardiovascular Surgery, Children s National Medical Center, Washington, DC, USA
J Thorac Cardiovasc Surg 134:90-8. 2007..This study compares the midterm clinical outcome in patients undergoing valve repair by tricuspidization with cusp extension with those receiving a pulmonary autograft (Ross)...
- Bicuspidization of the unicuspid aortic valve: a new reconstructive approachHans Joachim Schäfers
Department of Thoracic and Cardiovascular Surgery, University Hospitals of Saarland, Homburg Saar, Germany
Ann Thorac Surg 85:2012-8. 2008..Unicuspid anatomy of the aortic valve is infrequent but may require intervention by age 40 for severe regurgitation. We propose a new repair technique for the regurgitant unicuspid valve by converting it into a bicuspid aortic valve...
- Genetic disruption of angiotensin II type 1a receptor improves long-term survival of mice with chronic severe aortic regurgitationMichio Nakanishi
Department of Medicine and Clinical Science, Kyoto University Graduate School of Medicine, Japan
Circ J 71:1310-6. 2007..In the present study it was examined whether blockade of angiotensin II type 1 receptor (AT1) could improve survival in cases of chronic severe AR...
- Causes of pure aortic regurgitation in patients having isolated aortic valve replacement at a single US tertiary hospital (1993 to 2005)William Clifford Roberts
Department of Pathology, Division of Cardiology, Baylor Heart and Vascular Institute, Baylor University Medical Center, 3500 Gaston Ave, Dallas, TX 75246, USA
Circulation 114:422-9. 2006..The causes of aortic regurgitation (AR) severe enough to warrant aortic valve replacement (AVR) have received little attention in the last 20 years...
- Severity of mitral and aortic regurgitation as assessed by cardiovascular magnetic resonance: optimizing correlation with Doppler echocardiographyEli V Gelfand
Department of Medicine Cardiovascular Division, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
J Cardiovasc Magn Reson 8:503-7. 2006..Therefore, we sought to define the CMR regurgitant fractions that best correlate with qualitative mild, moderate, and severe regurgitation by color Doppler echocardiography...
- Diagnostic performance of MDCT for detecting aortic valve regurgitationGudrun M Feuchtner
Clinical Department of Radiology II, Innsbruck Medical University, Anichstr 35, A 6020 Innsbruck, Austria
AJR Am J Roentgenol 186:1676-81. 2006..This study evaluates whether ECG-gated 16-MDCT coronary angiography provides a reliable imaging technique for detecting aortic regurgitation (AR)...
- Valvular heart disease: focus on womenCatherine M Otto
Division of Cardiology, University of Washington, Seattle, Washington 98195, USA
Cardiol Rev 15:291-7. 2007....
- Impact of anesthesia on valvular function in normal rats during echocardiographySteven Droogmans
Department of Cardiology, UZ Brussel, Belgium
Ultrasound Med Biol 34:1564-72. 2008..In conclusion, anesthesia causes hemodynamic changes that may result in functional valvular regurgitations in normal rats...
- 64-MDCT for diagnosis of aortic regurgitation in patients referred to CT coronary angiographyGudrun M Feuchtner
Clinical Department of Radiology II, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
AJR Am J Roentgenol 191:W1-7. 2008..Therefore, the purpose of this study was to evaluate whether aortic valve regurgitation can be diagnosed with 64-MDCT in comparison with transthoracic echocardiography...
- Quadricuspid aortic valve: a rare cause of aortic regurgitation and stenosisSelman Vefa Yildirim
Division of Pediatric Cardiology, Baskent University, Adana Training and Medical Research Center, Adana, Turkey
Turk J Pediatr 50:500-2. 2008..The patient was diagnosed as having a quadricuspid aortic valve associated with aortic regurgitation, severe aortic stenosis, and an ascending aortic aneurysm...
- Mid-term results of freestyle aortic stentless bioprosthetic valve: clinical impact of quantitative analysis of in-vivo three-dimensional flow velocity profile by magnetic resonance imagingHajime Matsue
Division of Cardiovascular Surgery, Department of Surgery, Osaka University Graduate School of Medicine, Osaka, Suita, Japan
J Heart Valve Dis 14:630-6. 2005..The study aim was to investigate the in-vivo flow profiles of a stentless aortic bioprosthetic valve by MRI flow quantification, and to identify the clinical implication of prosthesis size and implantation method...
- Doppler echocardiographic assessment of valvular regurgitation severity by measurement of the vena contracta: an in vitro validation studyJulia Mascherbauer
Department of Cardiology, Vienna General Hospital, University of Vienna, Vienna, Austria
J Am Soc Echocardiogr 18:999-1006. 2005..Measurements of the vena contracta (VC) by color Doppler echocardiography have been proposed but limited data are available on the actual accuracy of this method...
- Assessment of aortic regurgitation by live three-dimensional transthoracic echocardiographic measurements of vena contracta area: usefulness and validationLigang Fang
Division of Cardiovascular Diseases, University of Alabama at Birmingham, Birmingham, Alabama 35249, USA
Echocardiography 22:775-81. 2005..95), with improved dispersion between angiographic grades demonstrated by the 3D TTE technique. Live 3D TTE color Doppler measurements of VCA can be used for accurate assessment of AR and are comparable to assessment by aortography...
- Impact of prosthesis-patient size on functional recovery after aortic valve replacementColleen Gorman Koch
Department of Cardiothoracic Anesthesia, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Circulation 111:3221-9. 2005..Our objectives were to examine the impact of valve replacement, continuous prosthesis-patient size, and other factors on functional recovery after aortic valve replacement (AVR) with the Duke Activity Status Index (DASI)...
- Measurement of aortic valve anatomic regurgitant area using transesophageal echocardiography: implications for the quantitation of aortic regurgitationMehmet Ozkan
Kosuyolu Heart and Research Hospital, Istanbul, Turkey
J Am Soc Echocardiogr 15:1170-4. 2002..Various echocardiographic methods for the assessment of the severity of the aortic regurgitation (AR) by have been described with no general consensus...
- Aortic and mitral fenfluramine-phentermine valvulopathy in 64 patients treated with anorectic agentsK E Volmar
Department of Pathology, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Arch Pathol Lab Med 125:1555-61. 2001..Few published studies of the pathology of fenfluramine-phentermine (fen-phen) valvulopathy, described by Connolly and colleagues in 1997, have appeared...
- Evaluation of effective aortic regurgitant orifice area and its effect on aortic regurgitant volume with Doppler echocardiographyK Mizushige
Second Department of Internal Medicine, Kagawa Medical University, Japan
Angiology 51:241-6. 2000..The values of ROA by the two methods showed a good correlation (r = 0.93, p < 0.001). Thus, the authors conclude that the ROA is a basic determinant of the RV in AR and that color Doppler can be employed to precisely assess the ROA...
- Fenfluramine and phentermine and cardiovascular findings: effect of treatment duration on prevalence of valve abnormalitiesJ G Jollis
Division of Cardiology, Duke University Medical Center, Durham, NC 27710, USA
Circulation 101:2071-7. 2000..The prevalence and clinical significance of regurgitation among patients treated with these medications has yet to be fully established...
- Clinical and echocardiographic follow-up of patients previously treated with dexfenfluramine or phentermine/fenfluramineJ M Gardin
Division of Cardiology, St John Hospital and Medical Center, 22201 Moross Rd, PB II, Suite 470, Detroit, MI 48236, USA
JAMA 286:2011-4. 2001..Use of anorexigen therapy is associated with valvular abnormalities, although there is limited information on long-term changes in valvular regurgitation following discontinuation of these agents...
- Determination of vena contracta and its value in evaluating severity of aortic regurgitationMehmet Eren
Siyami Ersek Thoracic and Cardiovascular Surgery Center, Cardiology Department, Istanbul, Turkey
J Heart Valve Dis 11:567-75. 2002..The study aim was to quantify aortic regurgitation (AR) by using color Doppler imaging of the VC...
- Human tissue valves in aortic position: determinants of reoperation and valve regurgitationT P Willems
Department of Cardiothoracic Surgery, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
Circulation 103:1515-21. 2001..In both techniques, progression of aortic regurgitation over time is small but accelerated in young adults...
- Tricuspidization of incompetent bicuspid aortic valveKohei Kawazoe
Department of Cardiovascular Surgery, Iwate Medical University Memorial Heart Center, Chuodori 1 2 1, Morioka, Iwate, Japan
J Thorac Cardiovasc Surg 126:908-10. 2003
- Heart valvular disease in patients with Parkinson's disease treated with high-dose pergolideG Van Camp
Department of Cardiology, Vrije Universiteit Brussels, Belgium
Neurology 61:859-61. 2003..The findings suggest a possible role of high doses of pergolide in inducing restrictive valvular disease...
- Eight-year results after aortic valve replacement with the Freestyle stentless bioprosthesisDavid S Bach
Department of Medicine, Division of Cardiology, University of Michigan, Ann Arbor, 48109, USA
J Thorac Cardiovasc Surg 127:1657-63. 2004..We sought to describe the hemodynamic and clinical outcomes for the Freestyle aortic root bioprosthesis (Medtronic, Inc, Minneapolis, Minn) in a large multicenter cohort prospectively followed for 8 years...
- Use of pulse wave and color flow Doppler echocardiography in mouse models of human diseaseRichard D Patten
Division of Cardiology and the Molecular Cardiology Research Institute, Department of Medicine, New England Medical Center, Boston, 02111, USA
J Am Soc Echocardiogr 15:708-14. 2002..In addition, this study indicates that these modalities may be potentially useful to screen transgenic mice for valve abnormalities...
- Effect of fenfluramine-derivative diet pills on cardiac valves: a meta-analysis of observational studiesMolly Sachdev
Duke Clinical Research Institute and the School of Medicine, Duke University, Durham, NC, USA
Am Heart J 144:1065-73. 2002..We systematically reviewed evidence regarding the prevalence of valvular disease after fenfluramine exposure...
- Contemporary approach to aortic and mitral regurgitationJeffrey S Borer
Division of Cardiovascular Pathophysiology and The Howard Gilman Institute for Valvular Heart Diseases, Weill Medical College of Cornell University, New York, NY, USA
Circulation 108:2432-8. 2003
- Aortic valve replacement for the asymptomatic patient with aortic regurgitation: a new piece of the strategic puzzleJeffrey S Borer
Circulation 106:2637-9. 2002
- Impact of implant technique following freestyle stentless aortic valve replacementDavid S Bach
Department of Medicine, Division of Cardiology, University of Michigan, Ann Arbor, USA
Ann Thorac Surg 74:1107-13; discussion 1113-4. 2002..The purpose of the present study was to determine whether implant technique of the Freestyle aortic root bioprosthesis impacts clinical outcomes or hemodynamic performance...
- Appetite suppressants and valvular heart disease in a population-based sample: the HyperGEN studyVittorio Palmieri
Weill Medical College of Cornell University, New York, New York 10021, USA
Am J Med 112:710-5. 2002..We assessed whether the use of the appetite suppressants fenfluramine/dexfenfluramine, either alone or with phentermine, was associated with aortic regurgitation while adjusting for these variables...
- Prevalence and determinants of valvulopathy in patients treated with dexfenfluramineB K Shively
Cardiology Divisions of Oregon Health Sciences University, Portland, OR, USA
Circulation 100:2161-7. 1999..Valve regurgitation has been associated with dexfenfluramine, but its prevalence and severity are uncertain. Additional factors that may contribute to valve regurgitation in patients exposed to this drug are poorly understood...
- Rapid Flow Evaluaton by Magnetic Resonance ImagingMark Doyle; Fiscal Year: 2006..Following the development stage, clinical application will be made to patients with aortic valvular diseases. ..
- Iron and AtherosclerosisSubha Raman; Fiscal Year: 2006..Subgroup analyses will include comparison of the presence of iron symptomatic versus asymptomatic patients and women versus age-matched men. ..
- Ischemic Arrest, Cytokines, and Organ DysfunctionJames Niemann; Fiscal Year: 2008..In aim 3, the effect of anti-TNF therapy on long-term survival and neurologic outcome will be evaluated. [unreadable] [unreadable]..
- Genetic Basis of Aortic Aneurysms/DissectionsDianna Milewicz; Fiscal Year: 2009..Therefore, identification of the genes that predispose individuals to TAAD is critical in preventing premature deaths due to dissections. ..
- Libman-Sacks Endocarditis and NPSLECarlos Roldan; Fiscal Year: 2009....
- DETERMINANTS OF PROCEDURE USE IN MYOCARDIAL INFARCTIONJames Jollis; Fiscal Year: 2003..We will also examine "which rate is right?" by comparing adjusted outcomes (mortality, resource use, and costs), and by comparing procedure use to approaches based on medical evidence. ..
- CARDIAC VALVE CALCIFICATIONEmile Mohler; Fiscal Year: 2003..2. To investigate mechanisms of valve calcification using a cell culture model of calcification. 3. To examine therapeutic strategies to inhibit valve calcification with a bisphosphonate in cell culture. ..
- MICROSCOPIC CARDIAC MATERIAL PROPERTIES IN AGINGSamuel Wickline; Fiscal Year: 2002....
- Thrombophilia In Cryptogenic Stroke (THICK) StudyJORGE KIZER; Fiscal Year: 2006..Interactions among thrombophilias, thrombophilias and traditional cardiovascular risk factors, and thrombophilias and other potential cardiac sources of embolism will also be investigated. ..
- STICH Trial Radionuclide Core LaboratoryRobert Bonow; Fiscal Year: 2007..abstract_text> ..
- Targeting MMPS to Image AtherosclerosisJagat Narula; Fiscal Year: 2007..The extent of inflammation and MMP expression in the plaques will be ascertained histopathologically. [unreadable] (End of Abstract) [unreadable] [unreadable] [unreadable]..
- SPECIFIC TISSUE TARGETED ULTRASONIC CONTRAST AGENTSamuel Wickline; Fiscal Year: 2002....
- CHARACTERIZING MICROFIBRIL ABNORMALITIES IN SCLERODERMADianna Milewicz; Fiscal Year: 2003..The research proposed in this grant will determine the contribution of abnormalities in fibrillin-1-containing microfibrils to the activation of fibroblasts, which leads to the fibrosis that characterizes SSc. ..
- ULTRASONIC TISSUE CHARACTERIZATION OF CARDIAC REMODELINGSamuel Wickline; Fiscal Year: 2004....
- ANGIOTENSIN-II BLOCKADE IN MITRAL REGURGITATIONMaurice Enriquez Sarano; Fiscal Year: 2004..The results of this clinical trial should provide strong evidence regarding medical treatment of patients with organic MR and define future strategies to minimize mortality and morbidity of organic MR. ..
- Imaging Apoptosis to Detect Unstable Atheromatous PlaqueJagat Narula; Fiscal Year: 2004..The impending surgical intervention will allow histopathological evaluation of the endarterectomy specimens to define potential utility of annexin imaging. ..
- Neuroprotection with serpins during cardiac surgeryRichard A Jonas; Fiscal Year: 2010..The final phase will study mechanisms of vascular protection afforded by aprotinin. The proposed study has the potential to reduce the risk of brain injury in children and adults undergoing heart surgery. ..