heart neoplasms

Summary

Top Publications

  1. pmc Multidetector CT and MR imaging of cardiac tumors
    Eun Young Kim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135 710, Korea
    Korean J Radiol 10:164-75. 2009
  2. doi Outcomes after surgical resection of cardiac sarcoma in the multimodality treatment era
    Faisal G Bakaeen
    Department of Cardiothoracic Surgery, Baylor College of Medicine, Houston, Tex 77030, USA
    J Thorac Cardiovasc Surg 137:1454-60. 2009
  3. doi Cardiac tumors: optimal cardiac MR sequences and spectrum of imaging appearances
    David H O'Donnell
    Cardiac CT and MRI Program, Department of Radiology and Cardiology, St Vincent s University Hospital, Elm Park, Dublin 4, Ireland
    AJR Am J Roentgenol 193:377-87. 2009
  4. ncbi Metastases to the heart
    K Reynen
    Department of Internal Medicine II, University of Dresden, Heart Center Dresden, Dresden, Germany
    Ann Oncol 15:375-81. 2004
  5. doi Benign cardiac tumors and tumorlike conditions
    Deepali Jain
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Ann Diagn Pathol 14:215-30. 2010
  6. pmc Papillary fibroelastoma of the aortic valve--a case report and literature review
    Neerod K Jha
    Division of Adult Cardiac Surgery, Institute of Cardiac Sciences, Sheikh Khalifa Medical City Managed by Cleveland Clinic, PO Box 51900, Abu Dhabi UAE
    J Cardiothorac Surg 5:84. 2010
  7. pmc Cardiac tumours in children
    Orhan Uzun
    Department of Paediatric Cardiology, University Hospital of Wales, Heath Park Cardiff, CF14 4XW, Wales, UK
    Orphanet J Rare Dis 2:11. 2007
  8. ncbi Cardiac myxoma: its origin and tumor characteristics
    Jun Amano
    Department of Surgery, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto, Nagano 390 8621, Japan
    Ann Thorac Cardiovasc Surg 9:215-21. 2003
  9. doi A novel kind of tumor type-characteristic junction: plakophilin-2 as a major protein of adherens junctions in cardiac myxomata
    Steffen Rickelt
    Helmholtz Group for Cell Biology, German Cancer Research Center, Heidelberg, Germany
    Mod Pathol 23:1429-37. 2010
  10. doi A matter of the heart: myocardial metastases in neuroendocrine tumors
    H Jann
    Department of Hepatology and Gastroenterology, Charite, Berlin, Germany
    Horm Metab Res 42:967-76. 2010

Research Grants

Detail Information

Publications289 found, 100 shown here

  1. pmc Multidetector CT and MR imaging of cardiac tumors
    Eun Young Kim
    Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul 135 710, Korea
    Korean J Radiol 10:164-75. 2009
    ..Presurgical assessment of malignant cardiac tumors with the use of MDCT and MRI may allow determination of the resectability of tumors and planning for the reconstruction of cardiac chambers...
  2. doi Outcomes after surgical resection of cardiac sarcoma in the multimodality treatment era
    Faisal G Bakaeen
    Department of Cardiothoracic Surgery, Baylor College of Medicine, Houston, Tex 77030, USA
    J Thorac Cardiovasc Surg 137:1454-60. 2009
    ..Primary cardiac sarcomas are rare tumors carrying poor prognosis. Resection remains the primary therapy. Especially in recent years, chemotherapy and radiation have been used adjunctively...
  3. doi Cardiac tumors: optimal cardiac MR sequences and spectrum of imaging appearances
    David H O'Donnell
    Cardiac CT and MRI Program, Department of Radiology and Cardiology, St Vincent s University Hospital, Elm Park, Dublin 4, Ireland
    AJR Am J Roentgenol 193:377-87. 2009
    ..This article reviews the optimal cardiac MRI sequences for and the spectrum of imaging appearances of cardiac tumors...
  4. ncbi Metastases to the heart
    K Reynen
    Department of Internal Medicine II, University of Dresden, Heart Center Dresden, Dresden, Germany
    Ann Oncol 15:375-81. 2004
  5. doi Benign cardiac tumors and tumorlike conditions
    Deepali Jain
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Ann Diagn Pathol 14:215-30. 2010
    ..This comprehensive and up-to-date review describes the key clinical, gross, and histologic findings for 16 distinct entities. It also provides differential diagnoses and key facts to differentiate between similar appearing tumors...
  6. pmc Papillary fibroelastoma of the aortic valve--a case report and literature review
    Neerod K Jha
    Division of Adult Cardiac Surgery, Institute of Cardiac Sciences, Sheikh Khalifa Medical City Managed by Cleveland Clinic, PO Box 51900, Abu Dhabi UAE
    J Cardiothorac Surg 5:84. 2010
    ..Also, possibility of this diagnosis should be kept in mind while managing cardiac or valvular tumours...
  7. pmc Cardiac tumours in children
    Orhan Uzun
    Department of Paediatric Cardiology, University Hospital of Wales, Heath Park Cardiff, CF14 4XW, Wales, UK
    Orphanet J Rare Dis 2:11. 2007
    ..Surgery, chemotherapy and radiotherapy may prolong survival. The prognosis for malignant primary cardiac tumours is generally extremely poor...
  8. ncbi Cardiac myxoma: its origin and tumor characteristics
    Jun Amano
    Department of Surgery, Shinshu University School of Medicine, 3 1 1 Asahi, Matsumoto, Nagano 390 8621, Japan
    Ann Thorac Cardiovasc Surg 9:215-21. 2003
    ..These genetic and molecular approaches to cardiac myxoma may prompt the development of therapeutic modalities for treatment of malignancies and cardiac cell regeneration...
  9. doi A novel kind of tumor type-characteristic junction: plakophilin-2 as a major protein of adherens junctions in cardiac myxomata
    Steffen Rickelt
    Helmholtz Group for Cell Biology, German Cancer Research Center, Heidelberg, Germany
    Mod Pathol 23:1429-37. 2010
    ..We propose to examine the marker value of Pkp2 in clinical diagnoses of cardiac myxomata and to develop Pkp2-targeted therapeutic reagents...
  10. doi A matter of the heart: myocardial metastases in neuroendocrine tumors
    H Jann
    Department of Hepatology and Gastroenterology, Charite, Berlin, Germany
    Horm Metab Res 42:967-76. 2010
    ..Management of cardiac metastases requires close cooperation between specialists of internal medicine, nuclear medicine, and cardiac surgery...
  11. ncbi Primary cardiac tumours: eighteen years of surgical experience on 21 patients
    Nicolo Piazza
    McGill University, 3755 Cote Ste Catherine Road, Montreal, Quebec H3T 1E2, Canada
    Can J Cardiol 20:1443-8. 2004
    ..The literature on primary cardiac tumours is relatively limited because of their rare occurrence...
  12. ncbi Sex distribution in cardiac myxomas
    Dong Hi Anthony Yoon
    Department of Internal Medicine, Baylor University Medical Center, Dallas, Texas 75246, USA
    Am J Cardiol 90:563-5. 2002
  13. doi Cardiac myxoma the great imitators: comprehensive histopathological and molecular approach
    Igor Gosev
    Department of Cardiac Surgery University Hospital Centre Zagreb, Croatia Kišpatićeva 12, 10 000 Zagreb, Croatia
    Int J Cardiol 164:7-20. 2013
    ....
  14. doi Surgical excision of cardiac myxomas: twenty years experience at a single institution
    Andrea Garatti
    Division of Cardiac Surgery and First Vascular Surgery Unit, Istituto di Ricovero e Cura a Carattere Scientifico, Policlinico San Donato Hospital, San Donato Milanese, and Faculty of Medicine, University of Milan, Milan, Italy
    Ann Thorac Surg 93:825-31. 2012
    ..Primary cardiac tumors are quite uncommon and myxomas constitute the major proportion among these masses. The present study summarizes our 20-year clinical experience with surgical resection of intracardiac myxomas...
  15. ncbi Primary cardiac tumours in a paediatric population
    R A Elderkin
    Queensland Centre for Congenital Heart Disease, Prince Charles Hospital, Chermside, Queensland, Australia
    J Paediatr Child Health 38:173-7. 2002
    ..To review the presentation, diagnosis, histology and outcome of primary cardiac tumours presenting to a paediatric cardiac unit over a 20-year period...
  16. ncbi Primary lymphoma of the heart
    M Mejhert
    Division of Internal Medicine, Karolinska Institutet Danderyd Hospital, Sweden
    Scand Cardiovasc J 34:606-8. 2000
    ..Early identification is essential for optimum treatment. We present a case of malignant lymphoma of the heart, where treatment led to remission from cardiac growth of the tumor...
  17. doi A case of reversible ventricular tachycardia and complete atrioventricular block associated with primary cardiac B-cell lymphoma
    Yasuaki Tanaka
    Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kumamoto University, Kumamoto, Japan
    Pacing Clin Electrophysiol 32:816-9. 2009
    ..He was then diagnosed with primary cardiac lymphoma. The chemotherapy and radiotherapy resulted in the disappearance of the mass. Complete remission has been maintained for 8 years after the therapy, and no VT or C-AVB has been detected...
  18. ncbi Cardiac tumours: diagnosis and management
    Jagdish Butany
    Department of Pathology, Toronto Medical Laboratories, Toronto General Hospital, University Health Network, Canada
    Lancet Oncol 6:219-28. 2005
    ..Patients with sarcomas live for a mean of 3 months to 1 year, and those with lymphomas live up to 5 years if treated, but usually die within 1 month if untreated...
  19. pmc Malignant peripheral nerve sheath tumor associated with neurofibromatosis type 1, with metastasis to the heart: a case report
    Masanori Kitamura
    Department of Pathology, Osaka Medical Center for Cancer and Cardiovascular Diseases, 1 3 3 Nakamichi, Higashinari, Osaka, Japan
    Diagn Pathol 5:2. 2010
    ..Since then, the patient has had repeated local recurrences in spite of repeated surgical treatment and adjuvant chemotherapy. He has developed previous metastases of the lung and heart. The patient died of cardiac involvement...
  20. pmc Cardiovascular magnetic resonance and PET-CT of left atrial paraganglioma
    Anderanik Tomasian
    Department of Radiological Sciences, University of California at Los Angeles, USA
    J Cardiovasc Magn Reson 12:1. 2010
    ....
  21. ncbi CT and MR imaging of pericardial disease
    Zhen J Wang
    Department of Radiology, Box 0628, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA 94143 0628, USA
    Radiographics 23:S167-80. 2003
    ..Given the many potential applications of these modalities in the evaluation of pericardial diseases, familiarity with the CT and MR imaging features of these diseases is important...
  22. doi Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis
    Zhirong Yin
    Department of Molecular Virology, Immunology, and Molecular Genetics, Ohio State University, Columbus, USA
    Circulation 117:1414-22. 2008
    ..Mouse models of this genetic defect have been unsatisfactory because homozygote null animals die early in development and heterozygotes do not exhibit a cardiac phenotype...
  23. doi Malignant primary cardiac tumors: review of a single institution experience
    Lijo Simpson
    Division of Medical Oncology, Mayo Clinic Cancer Center, Mayo Clinic, Rochester, MN 55905, USA
    Cancer 112:2440-6. 2008
    ..Primary cardiac sarcomas are uncommon. The authors undertook to review the Mayo Clinic's experience with primary cardiac sarcomas consisting of 34 patients seen over a 32-year period...
  24. ncbi Combined heart and lung transplantation for unresectable primary cardiac sarcoma
    Susan M Talbot
    Departments of Medicine and Surgery, Columbia University, College of Physicians and Surgeons, New York, NY 10032, USA
    J Thorac Cardiovasc Surg 124:1145-8. 2002
    ..Removal of all cardiopulmonary structures involved by tumor followed by orthotopic allotransplantation has been proposed to improve long-term survival...
  25. pmc Carney complex (CNC)
    Jerome Bertherat
    Centre de Référence Maladies Rares de la Surrénale, Service d endocrinologie, Hopital Cochin, INSERM U 567, CNRS UMR 8104, Institut Cochin, Universite Rene Descartes Paris 5, Paris, 75014, France
    Orphanet J Rare Dis 1:21. 2006
    ..Bilateral adrenalectomy is the most common treatment for Cushing's syndrome due to PPNAD...
  26. ncbi Clinical presentation of left atrial cardiac myxoma. A series of 112 consecutive cases
    L Pinede
    Department of Internal Medicine, Edouard Herriot Hospital, 69437 Lyons, France
    Medicine (Baltimore) 80:159-72. 2001
    ..The recurrence rate is low (5%), but long-term follow-up and serial echocardiography are advisable especially for young patients...
  27. doi Cardiac sarcomas: an update
    Augusto Orlandi
    Department of Anatomic Pathology, Tor Vergata University, Via Montpellier, Rome, Italy
    J Thorac Oncol 5:1483-9. 2010
    ....
  28. ncbi A huge obstructive myxoma located in the right heart without causing any symptom
    Murat Yuce
    Int J Cardiol 114:405-6. 2007
    ..We report a huge cardiac myxoma originated from right atrium. It was moving between right atrium and ventricle without any symptoms...
  29. doi Cardiac metastases
    Abrahim Al-Mamgani
    Department of Radiation Oncology, Erasmus MC Daniel den Hoed Cancer Center, Groene Hilledijk 301, Rotterdam, The Netherlands
    Int J Clin Oncol 13:369-72. 2008
    ..1% vs 3.8%; Kruskal-Wallis rank test; P = 0.039). Special attention was given to the role of radiotherapy in the management of cardiac metastases...
  30. ncbi A 30-year analysis of cardiac neoplasms at autopsy
    Jagdish Butany
    Department of Pathology, Toronto General Hospital University Health Network, Ontario
    Can J Cardiol 21:675-80. 2005
    ..Consequently, cardiac neoplasms, especially metastatic ones, are often not discovered until autopsy...
  31. ncbi Transplantation of undifferentiated murine embryonic stem cells in the heart: teratoma formation and immune response
    Jeannette Nussbaum
    Department of Pathology, University of Washington, Seattle, WA, USA
    FASEB J 21:1345-57. 2007
    ..Successful cardiac repair strategies involving ES cells will need to control cardiac differentiation, avoid introducing undifferentiated cells, and will likely require immune modulation to avoid rejection...
  32. doi Clinicopathologic study of 24 patients with primary cardiac sarcomas: a 10-year single institution experience
    Chul Hwan Kim
    Department of Pathology, Weill Medical College of Cornell University, Methodist Hospital, Houston, TX 77030, USA
    Hum Pathol 39:933-8. 2008
    ..The survival of cardiac sarcomas is poor...
  33. ncbi Pericardial tamponade as initial presentation of papillary thyroid carcinoma
    F M González Valverde
    Department of Surgery, Hospital de la Vega Baja, Orihuela, Spain
    Eur J Surg Oncol 31:205-7. 2005
    ..Although malignant pericardial effusion is a known complication of thyroid cancer, it is rarely the first manifestation and shows a relatively favourable prognosis despite widespread metastases if adequate treatment is given...
  34. ncbi Thymoma arising within cardiac myxoma
    Dylan V Miller
    Division of Anatomic Pathology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Surg Pathol 29:1208-13. 2005
    ..The most likely explanation for this extremely unusual finding is neoplastic transformation of thymic rests within a myxoma...
  35. doi Survival after resection of primary cardiac tumors: a 48-year experience
    Andrew W ElBardissi
    MPH, Department of Surgery, Brigham and Women s Hospital and Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA
    Circulation 118:S7-15. 2008
    ..To date, however, there have been no studies examining survival characteristics of patients who undergo surgical resection...
  36. ncbi [Cardiac rhabdomyoma and apoptosis: are regression controlled by the body?]
    D Satge
    Laboratoire d Anatomie Pathologique, CHG de Tulle
    Arch Mal Coeur Vaiss 85:603-8. 1992
    ..Regression of rhabdomyomas may be compared with other observations of benign and malignant tumours which show spontaneous involution in early life. Medical treatment is advisable even in the absence of life-threatening symptoms...
  37. pmc Primary cardiac sarcomas: a clinicopathologic analysis of a series with follow-up information in 17 patients and emphasis on long-term survival
    Paul J Zhang
    Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Hum Pathol 39:1385-95. 2008
    ..Tumor grade appeared to be prognostically important in cardiac sarcoma. Long survival was achieved in patients who survived the initial surgery well...
  38. doi Giant left atrial myxoma: an unusual cause of acute pulmonary edema
    Rodolfo Citro
    U O UTIC Cardiologia, San Luca Hospital, Vallo della Lucania, Italy
    J Am Soc Echocardiogr 21:978.e1-3. 2008
    ..We report a case of a huge left atrial myxoma with an unusual clinical presentation characterized by acute pulmonary edema. The possible pathophysiologic mechanism has been discussed...
  39. ncbi Myxoid tissue fragments in femoral embolectomy material: cardiac myxoma versus myxoid thrombus--a diagnostic dilemma
    Riza Dogan
    Department of Cardiovascular Surgery, Medical Faculty, Hacettepe University, Ankara, Turkey
    Anadolu Kardiyol Derg 7:105-6. 2007
  40. ncbi Vascular endothelial growth factor is an autocrine growth factor for cardiac myxoma cells
    Hironosuke Sakamoto
    Departments of General Medicine, Gunma University Graduate School of Medicine, Maebashi, Maebashi, Japan
    Circ J 68:488-93. 2004
    ..The purpose of this study was to determine whether cardiac myxoma cells possess a VEGF-autocrine system that regulates tumor growth...
  41. ncbi Malignant tumours of the heart: a review of tumour type, diagnosis and therapy
    S Neragi-Miandoab
    Department of Surgery, University Hospitals of Cleveland, Case Western Reserve University, School of Medicine, Cleveland, OH 44106, USA
    Clin Oncol (R Coll Radiol) 19:748-56. 2007
    ..Surgery is the cornerstone of therapy. However, a multi-treatment approach, including chemotherapy, radiation as well as evolving approaches such as gene therapy, might provide a better palliative and curative result...
  42. doi Thoracoscopic subtotal pericardiectomy and right atrial mass resection in a dog
    Denise M Crumbaker
    Aspen Meadow Veterinary Specialists, 104 S Main St, Longmont, CO 80501, USA
    J Am Vet Med Assoc 237:551-4. 2010
    ..A 10-year-old spayed female Corgi mix was examined for a 3-week history of lethargy and weight gain...
  43. doi Concurrent splenic and right atrial mass at presentation in dogs with HSA: a retrospective study
    Sarah E Boston
    Department of Clinical Studies, University of Guelph, Guelph, ON, Canada
    J Am Anim Hosp Assoc 47:336-41. 2011
    ..7%, which is less than previously reported. For dogs with right atrial HSA, the risk of metastasis to nonsplenic sites decreases with age...
  44. pmc Successful surgical resection of infected left atrial myxoma in a case complicated with disseminated intravascular coagulation and multiple cerebral infarctions: case report
    Daisuke Yoshioka
    Department of Cardiovascular Surgery, Osaka National Hospital, 2 14 Hoenzaka, Chuo Ku, Osaka City, Osaka, 540 0006, Japan
    J Cardiothorac Surg 6:68. 2011
    ..Even though this report is limited to a case, only aggressive and prompt surgical intervention could relieve the intractable conditions in such a patient with extremely high risk...
  45. pmc Cardiac metastases
    R Bussani
    Department of Pathologic Anatomy, University of Trieste, Trieste, Italy
    J Clin Pathol 60:27-34. 2007
    ..This paper attempts to review the pathophysiology of cardiac metastatic disease, epidemiology and clinical presentation of cardiac metastases, and pathological characterisation of the lesions...
  46. pmc Atypical vessels as an early sign of intracardiac myxoma?
    Hans Peter Dübel
    Medical Clinic for Cardiology, Angiology, Pulmology, Charite Campus Mitte, University Medicine Berlin, Germany
    Cardiovasc Ultrasound 2:13. 2004
    ..The retrospective analysis of the pre-intervention coronary angiography revealed atypical vessels in the atrial septum, which are interpreted as early signs of myxoma...
  47. ncbi Epidemiological and pathological characteristics of cardiac tumors: a clinical study of 242 cases
    Kun Yu
    Division of Cardiothoracic Surgery, Extracorporeal Circulation and Anatomic Pathology, Cardiovascular Institute and Fuwai Hospital, CAMS and PUMS, Beijing 100037, China
    Interact Cardiovasc Thorac Surg 6:636-9. 2007
    ..This study, using a relatively large sample, reveals the clinical incidences and pathological characteristics of various cardiac tumors in the Chinese population...
  48. ncbi Giant cardiac myxoma
    Peter Barlis
    Department of Cardiology, Austin Hospital, P O Box 5555, Heidelberg, VIC 3084, Australia
    Heart Lung Circ 16:389-91. 2007
    ..The resultant outcome was excellent with the patient achieving complete recovery from long term disabling symptoms...
  49. ncbi An unusual cause of sudden death: cardiac myxoma
    N Turkmen
    Uludag University Medical Faculty, Forensic Medicine Department, Görükle Council of Forensic Medicine of Turkey, Bursa Morgue Department, Bursa, Turkey
    Adv Ther 24:529-32. 2007
    ..This report describes an unusual cause of sudden death and the autopsy findings for a 73-year-old man with left atrial myxoma...
  50. ncbi Massive pulmonary embolus complicating left atrial myxoma
    N Kang
    Department of Cardiothoracic Surgery, Royal Prince Alfred Hospital, Sydney, NSW 2050, Australia
    J Thorac Cardiovasc Surg 121:814-5. 2001
    ..We report a case of a massive pulmonary thromboembolus complicating a left atrial myxoma in the absence of an atrial or ventricular septal defect...
  51. ncbi Therapy insight: malignant primary cardiac tumors
    Michael J Reardon
    Methodist DeBakey Heart Center, Houston, TX 77030, USA
    Nat Clin Pract Cardiovasc Med 3:548-53. 2006
    ..Surgical resection of this sarcoma type often requires pneumonectomy and can require pulmonary root replacement...
  52. ncbi A large left atrial myxoma
    Jagdish Butany
    Department of Pathology, Toronto General Hospital, Toronto, Canada
    J Card Surg 19:547-51. 2004
  53. ncbi Production of endothelin-1 and big endothelin-1 by human cardiac myxoma cells--implications of the origin of myxomas--
    Hironosuke Sakamoto
    Department of General Practice Medicine, Gunma University Graduate School of Medicine, Showa machi, Maebashi, Gunma, Japan
    Circ J 68:1230-2. 2004
    ..Although the origin of cardiac myxomas is still controversial, the 2 main hypotheses are that the tumor cells originate either from multipotential mesenchymal cells or from endocardial neural tissue...
  54. ncbi Left atrial myxoma presenting as acute inferior wall infarction--a case report
    J Butany
    Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto General Hospital, Toronto, Ontario, Canada
    J Card Surg 21:479-80. 2006
  55. ncbi Multiple cardiac myxomas with pulmonary arterial obstruction and acute right heart failure
    Koichi Sughimoto
    Department of Cardiovascular Surgery, Cardiovascular Center of Sendai, 21 1 Honda chou, Izumi ku, Sendai 981 3107, Japan
    Jpn J Thorac Cardiovasc Surg 52:530-3. 2004
    ..Following the removal of the tumor, symptoms improved drastically. The postoperative course was uneventful...
  56. ncbi Atrial myxomas: pathologic types, tumor location, and presenting symptoms
    Michael F Swartz
    State University of New York Upstate Medical University, Department of Cardiac Surgery, Syracuse, NY 13215, USA
    J Card Surg 21:435-40. 2006
    ..We examined whether differences in gross or microscopic appearance and location correlated with symptomatology, specifically congestive heart failure (CHF), neurologic symptoms, and embolic events...
  57. ncbi Inherited disposition to cardiac myxoma development
    David Wilkes
    Greenberg Division of Cardiology, Department of Medicine, Weill Medical College of Cornell University, 525 East 68th Street, New York, New York 10021, USA
    Nat Rev Cancer 6:157-65. 2006
    ..Ongoing investigations are exploring the intersection of R1alpha-dependent cell signalling with other gene products such as perinatal myosin, mutation of which can also cause cardiac myxomas...
  58. ncbi Leiomyosarcoma of the left atrium mimicking a left atrial myxoma
    Alessandro Mazzola
    Department of Cardiac Surgery, G Mazzini Hospital, Teramo, Italy
    J Thorac Cardiovasc Surg 131:224-6. 2006
  59. ncbi Successful excision of a cystic tumor of the atrioventricular nodal region
    Shunsuke Saito
    Department of Cardiovascular Surgery, National Cardiovascular Center, Suita, Japan
    Circ J 69:1293-4. 2005
    ..Histopathological examination revealed the mass to be a cystic tumor of the atrioventricular nodal region. A 5-year follow-up has revealed no sign of recurrence...
  60. ncbi Recurrent cardiac myxoma: why it occurs. A case report with literature review
    D Reber
    Department of Cardiothoracic Surgery, University Hospital, Rengensburg, Germany
    J Cardiovasc Surg (Torino) 42:345-8. 2001
    ..Familial disposition may also play a role in recurrent development. The abnormal DNA ploidy pattern of myxoma patients showed a high recurrence...
  61. doi Primary cardiac lymphoma
    Carlos E Miguel
    Department of Internal Medicine, Hospital de Base, Brazil
    Int J Cardiol 149:358-63. 2011
    ..Prognosis of PCL is poor with a median survival of 7months after initial diagnosis. Newer modalities including immunotherapy with rituximab or auto stem cell transplantation are promising in the treatment of this lethal condition...
  62. doi Novel strategies for recurrent cardiac myxoma
    Kaushalendra Singh Rathore
    Department of Cardiothoracic Surgery, Royal Adelaide Hospital, Adelaide, Southern Australia, Australia
    Ann Thorac Surg 85:2125-6. 2008
    ..This time, however, endoscopically assisted techniques were used. The tumor was excised with supplementary cryoablation. The patient made a quick recovery from this second procedure and has had no recurrence after a 1-year follow-up...
  63. pmc Myxoma at junction of inferior vena cava and right atrium: surgical excision
    Ahmad K Darwazah
    Department of Cardiac Surgery, Ramallah Hospital, West Bank, Ramallah, Israel
    Tex Heart Inst J 38:591-3. 2011
    ..The diagnosis was made with the aid of transesophageal echocardiography, which proved its superiority and accuracy in this application...
  64. ncbi Mitral valve recurrence of a left atrial myxoma
    Navid Sadeghi
    Department of Cardiac Surgery, Dr Shariati Hospital, Tehran University of Medical Sciences TUMS, Tehran, Iran
    Eur J Cardiothorac Surg 21:568-73. 2002
    ..Long-term follow-up of patients by echocardiography is advised for early detection of any recurrence...
  65. ncbi Echocardiographic and pathologic characteristics of primary cardiac tumors: a study of 149 cases
    Qingyi Meng
    Department of Emergency Medicine, Chinese PLA General Hospital, Beijing, PR China
    Int J Cardiol 84:69-75. 2002
    ..The locations of tumor involvement varied by types of tumor. Echocardiography may be a useful tool for early diagnosis of primary cardiac tumors...
  66. doi Pediatric heart tumors
    Allen Burke
    CVPath Institute, Gaithersburg, MD 20878, USA
    Cardiovasc Pathol 17:193-8. 2008
    ..Other rare tumors, including histiocytoid cardiomyopathy, hemangioma, germ cell tumors, and sarcomas, may occur in children in the heart and are discussed...
  67. ncbi Expression of basic fibroblast growth factor and its receptor-1 in cardiac myxoma
    H Fujisawa
    Second Department of Surgery, Shinshu University School of Medicine, Matsumoto, Japan
    J Cardiovasc Surg (Torino) 43:589-94. 2002
    ..To clarify the significance of basic fibroblast growth factor (bFGF) in angiogenesis or proliferative activity in cardiac myxoma, the expression of bFGF and its receptor (FGFR-1) were immunohistochemically examined...
  68. doi Low-grade fibromyxoid sarcoma: an unusual cardiac location
    Amedeo Ferlosio
    Department of Biomedicine and Prevention, Tor Vergata University, Rome, Italy
    Cardiovasc Pathol 22:e15-7. 2013
    ..Clinically, low-grade fibromyxoid sarcoma is characterized by a longer survival rate compared to other sarcomas, suggesting its consideration in the differential diagnosis of cardiac tumors with a myxoid appearance...
  69. doi Rare metastases of recurrent cervical cancer to the pericardium and abdominal muscle
    Hee Seung Kim
    Department of Obstetrics and Gynecology, Seoul National University Hospital, Seoul, South Korea
    Arch Gynecol Obstet 278:479-82. 2008
    ..Aggressive local and systemic treatments may provide significant palliation of associated symptoms...
  70. doi Cardiac tumors and associated arrhythmias in pediatric patients, with observations on surgical therapy for ventricular tachycardia
    Christina Y Miyake
    Department of Cardiology, Children s Hospital Boston, Massachusetts 02115, USA
    J Am Coll Cardiol 58:1903-9. 2011
    ..The aim of this study was to describe a large experience with primary cardiac tumors in pediatric patients, characterize associated arrhythmias, and expand knowledge of natural history and treatment options...
  71. ncbi Cardiac metastasis from poorly differentiated carcinoma of the cervix: a case report
    Emily S Miller
    Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Northwestern Feinberg School of Medicine, Chicago, Illinois, USA
    J Reprod Med 55:78-80. 2010
    ..Disease metastatic to the heart from cervical carcinoma is rare and associated with a poor prognosis. Multimodality treatment has been shown to provide palliative benefit...
  72. doi An uncommon cause of coronary artery ostial obstruction: papillary fibroelastoma
    Gabor Erdoes
    Department of Anesthesiology and Pain Therapy, University Hospital Bern, CH 3010 Bern, Switzerland
    Echocardiography 27:337-40. 2010
    ..The report underlies the importance of echocardiography in diagnosis and intraoperative treatment of this type of cardiac mass...
  73. ncbi Cardiac autotransplantation for primary cardiac tumors
    Michael J Reardon
    Methodist DeBakey Heart Center, The Methodist Hospital, Houston, USA
    Ann Thorac Surg 82:645-50. 2006
    ..We, therefore, reviewed our series of patients with complex left-sided primary cardiac tumors who underwent tumor resection with cardiac autotransplantation...
  74. ncbi Undifferentiated sarcoma of the heart: a rare clinicopathologic presentation
    Augusto Orlandi
    Anatomic Pathology and Cardiovascular Surgery Institutes, Tor Vergata University, Rome, Italy
    J Thorac Cardiovasc Surg 124:192-3. 2002
  75. ncbi Cardiac rhabdomyomas and obstructive left heart disease: histologically but not functionally benign
    M D Black
    Division of Cardiovascular Surgery, Hospital for Sick Children, Toronto, Ontario, Canada
    Ann Thorac Surg 65:1388-90. 1998
    ..However, surgical intervention sometimes is required for the extirpation of a rhabdomyoma from the left ventricular outflow tract...
  76. doi Primary right atrial cardiac osteosarcoma with congestive heart failure
    Tomotaka Dohi
    Department of Cardiovascular Medicine, Juntendo University, Tokyo, Japan
    Eur J Cardiothorac Surg 35:544-6. 2009
    ..Thereafter, the associated symptoms dramatically and rapidly diminished, and two days later the patient had recovered sufficiently to walk unaided. The short-term results of surgical tumor excision were excellent...
  77. ncbi [Cardiac fibroelastoma. Six operated cases and review of the literature]
    J M Grinda
    Service de Chirurgie Cardiothoracique et vasculaire, ,
    Arch Mal Coeur Vaiss 93:727-32. 2000
    ..Despite the benign histology, cardiac fibroelastomas should be excised because of their embolic complications. Absence of recurrence justifies conservative reconstruction of the affected valve...
  78. ncbi Central retinal artery occlusion as the initial sign of aortic valve papillary fibroelastoma
    E Lopez-Sanchez
    Hospital La Fe, Valencia, Spain
    Am J Ophthalmol 131:667-9. 2001
    ..We describe a central retinal artery occlusion in a young man who was subsequently found to have an aortic valve papillary fibroelastoma...
  79. ncbi [Malignant cardiac tumors]
    Philippe Debourdeau
    Service de Medecine Interne, Hôpital Desgenettes, 108, boulevard Pinel, 69003 Lyon
    Bull Cancer 91:136-46. 2004
    ..For primary cardiac neoplasms, surgery must be carefully discussed because operative intervention is often followed by rapid widespread metastases that adjuvant chemotherapy cannot avoid in most cases...
  80. ncbi Recurrence of cervical carcinoma manifesting as cardiac metastasis three years after curative resection
    Kyoko Inamura
    Department of Medicine and Biosystemic Science, Kyushu University Graduate School of Medical Sciences, Higashi ku, Fukuoka, Japan
    Am J Med Sci 328:167-9. 2004
    ..The right ventricular tumor recurred 4 months later and she died of heart failure. The possibility of late recurrence of cervical carcinoma in the heart should be considered even after curative resection...
  81. ncbi Aortic valve papillary fibroelastoma
    Abdallah Alawi
    Department of Cardiovascular and Thoracic Surgery, Hotel Dieu de France, Rue Adib Ishac, Beirut, Lebanon
    Cardiovasc Surg 10:65-7. 2002
    ..We describe the case of a 40-yr-old woman who presented with a neurological deficit caused by a papillary tumor of the aortic valve. Diagnosis was made by transesophageal echocardiaphy and the tumor was surgically removed...
  82. pmc Herpes simplex virus type 1 infection associated with atrial myxoma
    Yanwen Li
    Division of Biomedical Sciences, Imperial College Faculty of Medicine, London, United Kingdom
    Am J Pathol 163:2407-12. 2003
    ..Most infiltrating cells were cytotoxic T lymphocytes. These data suggest that HSV-1 infection is associated with some cases of sporadic atrial myxoma and that these may result from a chronic inflammatory lesion of endocardium...
  83. doi Pedunculated endocardial left ventricular fibroma presenting with cerebral and bilateral peripheral embolization
    Ahmad K Darwazah
    Heliopolis Cardiac Centre, National Cancer Institute, Cairo University, Cairo, Egypt
    Ann Thorac Surg 89:965-7. 2010
    ..Histopathologic examination confirmed the presence of fibroma associated with septic thrombus. The association of fibroma and embolization is rare...
  84. ncbi Cardiac metastases in malignant fibrous histiocytoma. A case report
    Francesco Recchia
    Unita Operativa di Oncologia, Ospedale Civile di Avezzano, AQ, Italy
    Tumori 92:76-8. 2006
    ..The response continued to improve with immunotherapy. The patient returned to normal physical activity. He died four years later due to a ventricular arrhythmia...
  85. ncbi Papillary fibroelastoma of the heart: report of two cases and review of the literature
    F Darvishian
    Department of Pathology, North Shore University Hospital, Manhasset, NY 11030, USA
    Ann Clin Lab Sci 31:291-6. 2001
    ..We report 2 cases of symptomatic papillary fibroelastoma, both of which presented with a stroke. Both patients underwent uneventful open-heart surgery. The literature is reviewed, with a compilation of 79 cases...
  86. pmc Leiomyosarcoma with partial rhabdomyoblastic differentiation: first case report of primary cardiac origin
    Yoichiro Okubo
    Department of Surgical Pathology, Toho University School of Medicine, 6 11 1 Omori Nishi, Ota ku, Tokyo 143 8541, Japan
    BMC Cancer 11:76. 2011
    ..Previous studies of leiomyosarcoma with rhabdomyoblastic differentiation have conducted to those arisen from another site, and they indicated a poorer prognosis of this tumor...
  87. pmc Splenic infarction associated with a mobile aortic valve lesion: a case report and review of the literature
    Philippe Gilbert
    Institut Universitaire de Cardiologie et de Pneumologie de Quebec, Quebec, Canada
    Can J Cardiol 25:e215-6. 2009
    ..The present case of PFE is reviewed for a better understanding of its pathology...
  88. doi Fetal demise secondary to massive rhabdomyoma in the early second trimester of pregnancy
    J Sharma
    Division of Pediatric Cardiology, Jamaica Hospital Medical Center, 8900, Van Wyck Expressway, Jamaica, NY 11418, USA
    Pediatr Cardiol 32:243-4. 2011
    ..This report presents a case of massive cardiac rhabdomyoma filling the entire right heart with pericardial extension, leading to hydrops and subsequent fetal death in the early second trimester of pregnancy...
  89. ncbi Clinical perspectives of primary cardiac lymphoma
    Ramesh M Gowda
    Division of Cardiology, Long Island College Hospital, Brooklyn, NY, USA
    Angiology 54:599-604. 2003
    ..Combination of chemotherapy and radiation therapy is considered as the treatment of choice. The survival is generally less than a month without treatment but has been prolonged up to 5 years with palliative treatments in selected cases...
  90. ncbi Different deformation patterns in intracardiac tumors
    Javier Ganame
    Pediatric Cardiology, University Hospitals Leuven, Herestraat 49, B 3000 Leuven, Belgium
    Eur J Echocardiogr 6:461-4. 2005
    ..In this case strain and strain rate analysis showed the absence of deformation in the tumor. These findings suggest that this new technique could be used to differentiate between different types of myocardial tumors...
  91. doi Cardiac paraganglioma: diagnostic and surgical challenges
    Jennie L Huo
    Division of Cardiovascular Medicine, Stanford University, Stanford, California 94305, USA
    J Card Surg 27:178-82. 2012
    ..In this case review, we discuss the challenges associated with the diagnosis and management of cardiac paragangliomas...
  92. ncbi Minimally invasive resection of papillary fibroelastoma in a high-risk patient
    Richard W Kim
    Division of Cardiothoracic Surgery, Department of Surgery, University of Pennsylvania, PA 19104, USA
    J Cardiovasc Med (Hagerstown) 8:639-41. 2007
    ....
  93. doi Characterization and management of cardiac tumors
    Javier G Castillo
    The Mount Sinai Medical Center, New York, NY 10029 6574, USA
    Semin Cardiothorac Vasc Anesth 14:6-20. 2010
    ....
  94. doi Left atrial paraganglioma: diagnosis and surgical management
    Fabrizio Ceresa
    Division of Cardiac Surgery, Papardo Piemonte Hospital, Messina, Italy
    Interact Cardiovasc Thorac Surg 10:1047-8. 2010
    ..The patient was discharged without complications and currently enjoys good health...
  95. ncbi Surgical management of symptomatic cardiac fibromas in children
    Ben Davies
    Cardiac Surgical Unit, Royal Children s Hospital, Melbourne, Australia
    J Thorac Cardiovasc Surg 133:254-5. 2007
  96. ncbi Cardiac valve papillary fibroelastoma: surgical excision for revealed or potential embolization
    Adam C Yopp
    Department of Surgery, Division of Cardiothoracic Surgery, Maimonides Medical Center, Brooklyn, New York 11219, USA
    J Card Surg 22:72-3. 2007
    ..We report here a case of pulmonary valve papillary fibroelastoma that was successfully managed with simple excision of the mass...
  97. ncbi Left ventricular cardiac fibroma in a child presenting with ventricular tachycardia
    Stacy Stratemann
    Vanderbilt University Medical Center, 1211 22nd Avenue South, Nashville, TN 37232 0002, USA
    Pediatr Cardiol 29:223-6. 2008
    ..These findings prompted a cardiac MRI, which demonstrated a discrete mass on his LV apex and free wall. Our case emphasizes that structural heart disease should be aggressively pursued in children presenting with ventricular tachycardia...
  98. doi Cardiac fibroma in an infant: complete resection after a Blalock-Taussig shunt as initial palliation
    Cheul Lee
    Department of Thoracic and Cardiovascular Surgery, Sejong Cardiovascular Center, Sejong General Hospital, Bucheon, Korea
    Ann Thorac Surg 90:1011-4. 2010
    ..This palliation allowed discharge from the hospital and provided good relief for the cyanosis until the tumor became resectable. The pathologic examination revealed a cardiac fibroma...
  99. pmc Primary cardiac sarcoma
    Maryam Hamidi
    Department of Human Oncology, School of Medicine and Public Health, University of Wisconsin, Madison, Wisconsin 53705, USA
    Ann Thorac Surg 90:176-81. 2010
    ..The presentation, management, and outcome of patients with primary cardiac sarcomas are not well defined. Furthermore, the role of adjuvant therapy has not been delineated in the management of primary cardiac sarcomas...
  100. ncbi PRKAR1A gene mutation in patients with cardiac myxoma
    T Mabuchi
    Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Takara machi 13 1, Kanazawa 920 8640, Japan
    Int J Cardiol 102:273-7. 2005
    ..We hypothesized that cardiac myxoma may be associated with PRKAR1A gene mutation and determined whether mutation in the PRKAR1A gene is the cause of familial and sporadic cardiac myxoma...
  101. ncbi Surgical management of thoracic malignancies invading the heart or great vessels
    Bernard J Park
    Thoracic Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Thorac Surg 78:1024-30. 2004
    ..We reviewed our experience of 10 patients treated surgically, either primarily or as a component of multimodality therapy, to assess feasibility and results...

Research Grants11

  1. DYSRHYTHMIAS OF THE RESPIRATORY OSCILLATOR
    David Paydarfar; Fiscal Year: 2002
    ....
  2. Nanostructuring and Molecular Imaging of Engineered Cardiovascular Tissues
    Joseph Wu; Fiscal Year: 2008
    ..With a multi-disciplinary team approach, we are confident that these combined efforts will accelerate the translation of nanotechnology-based tissue engineering to the clinical arena in the future. ..
  3. Angiogenesis and Cardiac Growth as Heart Failure Therapy
    Y Woo; Fiscal Year: 2008
    ..The candidate's institution, sponsor, and chairman provide a uniquely supportive, high-caliber, educationally stimulating environment highly conducive to the achievement of these goals. ..
  4. Cardiac MDCT for Early Triage of Patients with ACS
    Udo Hoffmann; Fiscal Year: 2008
    ..abstract_text> ..
  5. GENERAL CLINICAL RESEARCH CENTER
    Karen Antman; Fiscal Year: 2008
    ..abstract_text> ..
  6. Molecular Imaging of Cardiac Cell Transplantation
    Joseph Wu; Fiscal Year: 2008
    ..The goal is to use molecular imaging to guide stem cell therapy, which should translate into transplant protocols that are more reproducible, quantifiable, and beneficial. ..
  7. Training in Cancer Imaging with Novel Techniques
    Abass Alavi; Fiscal Year: 2007
    ..This will enable the Department of Radiology to increase the number of young clinical investigators and research scientists committed to excellence in academic oncology research using imaging technology. [unreadable] [unreadable]..
  8. Iron and Atherosclerosis
    Subha Raman; Fiscal Year: 2006
    ..Subgroup analyses will include comparison of the presence of iron symptomatic versus asymptomatic patients and women versus age-matched men. ..
  9. Physiology of Swallowing and Airway Protection
    David Paydarfar; Fiscal Year: 2006
    ..We will stimulate the ISLN (using optimum parameters from Aim 3) in patients with neurogenic dysphagia caused by focal cerebral damage, and we will test for improvement in swallowing and decrease in aspiration. ..
  10. ECHOCARDIOGRAPHIC STROKE PREDICTORS IN A TRI-ETHNIC COMM
    Marco Di Tullio; Fiscal Year: 2003
    ..This study will be the first prospective cohort study to evaluate the role of multiple echocardiographic risk factors for ischemic stroke in a community of whites, blacks and Hispanics living in the same area. ..
  11. Aortic, Cardiovascular Disease and Silent Brain Infarcts
    Marco Di Tullio; Fiscal Year: 2009
    ..The present application will help fill gaps in knowledge on silent brain infarcts and their risk factors in the elderly, and identify subjects at higher risk before a symptomatic stroke or other vascular event occurs. ..