surgical wound infection

Summary

Summary: Infection occurring at the site of a surgical incision.

Top Publications

  1. ncbi CDC definitions for nosocomial infections, 1988
    J S Garner
    Hospital Infections Program, Centers for Disease Control, Atlanta, Georgia
    Am J Infect Control 16:128-40. 1988
  2. pmc Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia
    Jacobus W A Burger
    Department of General Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
    Ann Surg 240:578-83; discussion 583-5. 2004
  3. ncbi Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee
    A J Mangram
    Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, Georgia 30333, USA
    Am J Infect Control 27:97-132; quiz 133-4; discussion 96. 1999
  4. ncbi Preventing surgical-site infections in nasal carriers of Staphylococcus aureus
    Lonneke G M Bode
    Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands
    N Engl J Med 362:9-17. 2010
  5. pmc Predictors of surgical site infections among patients undergoing major surgery at Bugando Medical Centre in Northwestern Tanzania
    Brian Mawalla
    Department of Microbiology Immunology Weill Bugando University College of Health Sciences, Mwanza, Tanzania
    BMC Surg 11:21. 2011
  6. ncbi Evaluating an evidence-based bundle for preventing surgical site infection: a randomized trial
    Thomas Anthony
    Department of Surgical Services, Veterans Affairs North Texas Health Care System, 4500 S Lancaster Road, Dallas, TX 75216, USA
    Arch Surg 146:263-9. 2011
  7. ncbi Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis
    Rabih O Darouiche
    Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX 77030, USA
    N Engl J Med 362:18-26. 2010
  8. ncbi Antimicrobial prophylaxis for cesarean delivery before skin incision
    Stephanie M Owens
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee Womens Research Institute, 300 Halket Street, Pittsburgh, PA 15213, USA
    Obstet Gynecol 114:573-9. 2009
  9. ncbi The impact of surgical-site infections following orthopedic surgery at a community hospital and a university hospital: adverse quality of life, excess length of stay, and extra cost
    James D Whitehouse
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Infect Control Hosp Epidemiol 23:183-9. 2002
  10. ncbi The impact of deep sternal wound infection on long-term survival after coronary artery bypass grafting
    Ioannis K Toumpoulis
    St Luke s Roosevelt Hospital Center at Columbia University, 45 East Eighty Ninth St, New York, NY 10128, USA
    Chest 127:464-71. 2005

Detail Information

Publications381 found, 100 shown here

  1. ncbi CDC definitions for nosocomial infections, 1988
    J S Garner
    Hospital Infections Program, Centers for Disease Control, Atlanta, Georgia
    Am J Infect Control 16:128-40. 1988
    ..Other hospitals may wish to adopt or modify them for use in their nosocomial infections surveillance programs...
  2. pmc Long-term follow-up of a randomized controlled trial of suture versus mesh repair of incisional hernia
    Jacobus W A Burger
    Department of General Surgery, Erasmus University Medical Center, Rotterdam, The Netherlands
    Ann Surg 240:578-83; discussion 583-5. 2004
    ..The objective of this study was to determine the best treatment of incisional hernia, taking into account recurrence, complications, discomfort, cosmetic result, and patient satisfaction...
  3. ncbi Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee
    A J Mangram
    Hospital Infections Program, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Public Health Service, US Department of Health and Human Services, Atlanta, Georgia 30333, USA
    Am J Infect Control 27:97-132; quiz 133-4; discussion 96. 1999
    ..g., laparoscopic cholecystectomy). Recommend specific antiseptic agents for patient preoperative skin preparations or for healthcare worker hand/forearm antisepsis. Hospitals should choose from products recommended for these activitie..
  4. ncbi Preventing surgical-site infections in nasal carriers of Staphylococcus aureus
    Lonneke G M Bode
    Department of Medical Microbiology and Infectious Diseases, Erasmus University Medical Center, Rotterdam, The Netherlands
    N Engl J Med 362:9-17. 2010
    ..Nasal carriers of Staphylococcus aureus are at increased risk for health care-associated infections with this organism. Decolonization of nasal and extranasal sites on hospital admission may reduce this risk...
  5. pmc Predictors of surgical site infections among patients undergoing major surgery at Bugando Medical Centre in Northwestern Tanzania
    Brian Mawalla
    Department of Microbiology Immunology Weill Bugando University College of Health Sciences, Mwanza, Tanzania
    BMC Surg 11:21. 2011
    ....
  6. ncbi Evaluating an evidence-based bundle for preventing surgical site infection: a randomized trial
    Thomas Anthony
    Department of Surgical Services, Veterans Affairs North Texas Health Care System, 4500 S Lancaster Road, Dallas, TX 75216, USA
    Arch Surg 146:263-9. 2011
    ..To determine if an evidence-based practice bundle would result in a significantly lower rate of surgical site infections (SSIs) when compared with standard practice...
  7. ncbi Chlorhexidine-Alcohol versus Povidone-Iodine for Surgical-Site Antisepsis
    Rabih O Darouiche
    Michael E DeBakey Veterans Affairs Medical Center and Baylor College of Medicine, Houston, TX 77030, USA
    N Engl J Med 362:18-26. 2010
    ..We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iodine...
  8. ncbi Antimicrobial prophylaxis for cesarean delivery before skin incision
    Stephanie M Owens
    Department of Obstetrics, Gynecology and Reproductive Sciences, University of Pittsburgh School of Medicine, Magee Womens Research Institute, 300 Halket Street, Pittsburgh, PA 15213, USA
    Obstet Gynecol 114:573-9. 2009
    ..To estimate the effect of a hospital-wide change in the timing of antimicrobial prophylaxis in cesarean deliveries on maternal and neonatal infections...
  9. ncbi The impact of surgical-site infections following orthopedic surgery at a community hospital and a university hospital: adverse quality of life, excess length of stay, and extra cost
    James D Whitehouse
    Department of Medicine, Duke University Medical Center, Durham, North Carolina 27710, USA
    Infect Control Hosp Epidemiol 23:183-9. 2002
    ..To measure the impact of orthopedic surgical-site infections (SSIs) on quality of life, length of hospitalization, and cost...
  10. ncbi The impact of deep sternal wound infection on long-term survival after coronary artery bypass grafting
    Ioannis K Toumpoulis
    St Luke s Roosevelt Hospital Center at Columbia University, 45 East Eighty Ninth St, New York, NY 10128, USA
    Chest 127:464-71. 2005
    ..To identify the impact of deep sternal wound infection (DSWI) on long-term survival after coronary artery bypass grafting (CABG)...
  11. ncbi Antimicrobial prophylaxis for surgery: an advisory statement from the National Surgical Infection Prevention Project
    Dale W Bratzler
    Oklahoma Foundation for Medical Quality, Oklahoma City, Oklahoma 73134 2627, USA
    Clin Infect Dis 38:1706-15. 2004
    ..This advisory statement provides an overview of other issues related to antimicrobial prophylaxis, including specific suggestions regarding antimicrobial selection...
  12. ncbi Four country healthcare associated infection prevalence survey 2006: overview of the results
    E T M Smyth
    Northern Ireland Healthcare Associated Infection Surveillance Centre, Belfast, UK
    J Hosp Infect 69:230-48. 2008
    ..Information obtained from this survey will contribute to the prioritisation of resources and help to inform Departments of Health, hospitals and other relevant bodies in the continuing effort to reduce HCAI...
  13. ncbi The clinical and economic impact of deep chest surgical site infections following coronary artery bypass graft surgery
    C S Hollenbeak
    Pennsylvania State College of Medicine, Hershey 17033, USA
    Chest 118:397-402. 2000
    ..To examine how deep chest surgical site infections following coronary artery bypass graft (CABG) surgery impact hospital inpatient length of stay (LOS), costs, and mortality...
  14. pmc Methods for identifying surgical wound infection after discharge from hospital: a systematic review
    Emily S Petherick
    Department of Health Sciences, University of York, Seebohm Rowntree Building, York, UK
    BMC Infect Dis 6:170. 2006
    ..Surveillance of SSIs is important because rates of SSI are viewed as a measure of hospital performance, however accurate detection of SSIs post-hospital discharge is not straightforward...
  15. ncbi A rational approach to perioperative fluid management
    Daniel Chappell
    Clinic of Anesthesiology, Ludwig Maximilians University, Munich, Germany
    Anesthesiology 109:723-40. 2008
    ..Therefore, undifferentiated fluid handling may increase the shift toward the interstitial space. Using the right kind of fluid in appropriate amounts at the right time might improve patient outcome...
  16. pmc Health-care-associated infection in Africa: a systematic review
    Sepideh Bagheri Nejad
    Clean Care is Safer Care, World Health Organization Patient Safety, Geneva, Switzerland
    Bull World Health Organ 89:757-65. 2011
    ..To assess the epidemiology of endemic health-care-associated infection (HAI) in Africa...
  17. ncbi Systematic review of the clinical effectiveness of wound-edge protection devices in reducing surgical site infection in patients undergoing open abdominal surgery
    Adrian Gheorghe
    Primary Care Clinical Sciences, University of Birmingham, United Kingdom
    Ann Surg 255:1017-29. 2012
    ..Assess the existing evidence on the clinical effectiveness of wound-edge protection devices (WEPDs) in reducing the surgical site infection (SSI) rate in patients undergoing open abdominal surgery...
  18. pmc Drug sensitivity patterns of bacterial isolates from septic post-operative wounds in a regional referral hospital in Uganda
    J R Anguzu
    Faculty of Veterinary Medicine, Makerere University, POBox 7062, Kampala, Uganda
    Afr Health Sci 7:148-54. 2007
    ..Advances in control of infections have not completely eradicated this problem because of development of drug resistance. Antimicrobial resistance can increase complications and costs associated with procedures and treatment...
  19. ncbi Wound infection in Tikur Anbessa hospital, surgical department
    Mulat Taye
    Department of Surgery, Tikur Anbessa Hospital, Addis Ababa, Ethiopia
    Ethiop Med J 43:167-74. 2005
    A prospective study of surgical wound infection has been conducted on 1754 surgical patients operated from January 1, 1999 to Dec 31, 1999 in Tikur Anbessa hospital...
  20. ncbi Wound protectors reduce surgical site infection: a meta-analysis of randomized controlled trials
    Janet P Edwards
    Division of General Surgery, University of Calgary, University of British Columbia, Canada
    Ann Surg 256:53-9. 2012
    ..A meta-analysis of randomized clinical trials (RCTs) was conducted to evaluate whether wound protectors reduce the risk of surgical site infection (SSI) after gastrointestinal and biliary tract surgery...
  21. ncbi Risk factors for surgical site infection in a Tanzanian district hospital: a challenge for the traditional National Nosocomial Infections Surveillance system index
    Jan Fehr
    Department of Medicine and Diagnostics, Swiss Tropical Institute, Basel, Switzerland
    Infect Control Hosp Epidemiol 27:1401-4. 2006
    ..Multidrug-resistant pathogens, such as methicillin-resistant Staphylococcus aureus and gram-negative pathogens expressing broad-spectrum beta-lactamases, have already emerged...
  22. pmc Treatment of gram-positive deep sternal wound infections in cardiac surgery--experiences with daptomycin
    Aron F Popov
    Department of Thoracic Cardiovascular Surgery, University of Gottingen, Germany
    J Cardiothorac Surg 6:112. 2011
    ..Based on these observations, daptomycin may offer a new treatment option for expediting surgical management of DSWI after cardiac surgery...
  23. ncbi Postoperative surgical site infection following acetabular fracture fixation
    Takashi Suzuki
    Department of Orthopaedic Surgery, Denver Health Medical Center, University of Colorado School of Medicine, 777 Bannock Street, Denver, CO 80204, USA
    Injury 41:396-9. 2010
    ..To reduce the incidence of SSI following acetabular fracture surgery, special attention should be directed at the care of obese patients, patients requiring ICU care, and patients with associated Morel-Lavallée lesions...
  24. pmc Interrupted time series analysis of vancomycin compared to cefuroxime for surgical prophylaxis in patients undergoing cardiac surgery
    K W Garey
    University of Houston, College of Pharmacy, Texas Medical Center, 1441 Moursund Street, Houston, TX 77030, USA
    Antimicrob Agents Chemother 52:446-51. 2008
    ....
  25. ncbi Surveillance of surgical site infections by surgeons: biased underreporting or useful epidemiological data?
    R Rosenthal
    Department of Surgery, Basel University Hospital, Switzerland
    J Hosp Infect 75:178-82. 2010
    ..Such a relatively inexpensive surveillance system is an option for hospitals without an ICT or for low risk surgical procedures. Moreover, trends in SSI rates can easily be detected, allowing early intervention...
  26. ncbi Surgical site infection: incidence and impact on hospital utilization and treatment costs
    Gregory de Lissovoy
    United BioSource Corporation, 7101 Wisconsin Avenue, Bethesda, MD 20814, USA
    Am J Infect Control 37:387-97. 2009
    ..Surgical site infections (SSIs) are serious operative complications that occur in approximately 2% of surgical procedures and account for some 20% of health care-associated infections...
  27. ncbi Cluster-randomized, crossover trial of the efficacy of plain soap and water versus alcohol-based rub for surgical hand preparation in a rural hospital in Kenya
    P M Nthumba
    Africa Inland Church Kijabe Hospital, Kijabe, Kenya
    Br J Surg 97:1621-8. 2010
    ..The aim of this cluster-randomized, crossover trial was to compare the efficacy of plain soap and water with an alcohol-based handrub for surgical hand preparation and prevention of surgical-site infection (SSI) in a Kenyan rural hospital...
  28. ncbi Preventing surgical site infection. Where now?
    H Humphreys
    Department of Clinical Microbiology, RCSI Education and Research Centre, Smurfit Building, Beaumont Hospital, PO Box 9063, Dublin 9, Ireland
    J Hosp Infect 73:316-22. 2009
    ..Finally, there is a need to convert theory into practice by the rigorous application of SSI healthcare bundles. Recent studies suggest that, with a multidisciplinary approach, simple measures can be effective in reducing SSI rates...
  29. ncbi Surgical site infection in children: prospective analysis of the burden and risk factors in a sub-Saharan African setting
    Emmanuel A Ameh
    Division of Pediatric Surgery, Department of Surgery, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria
    Surg Infect (Larchmt) 10:105-9. 2009
    ..Surgical site infections (SSI) add substantially to the morbidity of surgical patients. Our hypothesis was that the SSI rate is high in our setting, but there were no data regarding the prevalence and risk factors...
  30. pmc The concept of negative pressure wound therapy (NPWT) after poststernotomy mediastinitis--a single center experience with 54 patients
    Ina C Ennker
    Mediclin Herzzentrum Lahr Baden, Abteilung Herzchirurgie, Hohbergweg 2, 77933 Lahr, Germany
    J Cardiothorac Surg 4:5. 2009
    ..We report about our experiences and complications using this therapy in a set of 54 patients out of 3668 patients undergoing cardiac surgery in our institution between January 2005 and April 2007...
  31. ncbi Intranasal mupirocin reduces sternal wound infection after open heart surgery in diabetics and nondiabetics
    G E Cimochowski
    Department of Cardiac Surgery, Wilkes-Barre General Hospital, Pennsylvania, USA
    Ann Thorac Surg 71:1572-8; discussion 1578-9. 2001
    ..CONCLUSIONS: Prophylactic intranasal MPN is safe, inexpensive, and very effective in reducing the overall sternal wound infections by 66.6%...
  32. pmc Preventing surgical site infections: a surgeon's perspective
    R L Nichols
    Tulane University School of Medicine, New Orleans, Louisiana 70112 2699, USA
    Emerg Infect Dis 7:220-4. 2001
    ..Adherence to recommendations in the 1999 Centers for Disease Control and Prevention guidelines should reduce the incidence of infection in surgical patients...
  33. ncbi Surgical-site infections at Kilimanjaro Christian Medical Center
    H M Eriksen
    Department of General Practice and Community Health, University of Oslo, Norway
    J Hosp Infect 55:14-20. 2003
    ..The risk factors were similar to those reported from countries with more resources. The findings suggest that infection prevention measures, particularly antibiotic prophylaxis, should be re-evaluated...
  34. ncbi Surgical site infections: epidemiology, microbiology and prevention
    C D Owens
    Kimberly Clark Healthcare, Atlanta, GA, USA
    J Hosp Infect 70:3-10. 2008
    ....
  35. ncbi Total knee arthroplasty in diabetic patients: a study of 109 consecutive cases
    K Yang
    Department of Orthopaedic Surgery, Singapore General Hospital, Outram Road, Singapore 169608, Republic of Singapore
    J Arthroplasty 16:102-6. 2001
    ..The superficial and deep infection rates were higher when compared with a similar study in the general population. Maximum precautions should be taken for diabetic patients undergoing total knee arthroplasties...
  36. ncbi Determinants of surgical site infection after breast surgery
    M L Bertin
    Infection Control and Epidemiology, Cleveland Clinic Foundation, OH 44195, USA
    Am J Infect Control 26:61-5. 1998
    ..9% (3 infections for 332 procedures). CONCLUSIONS: Host factors may contribute to SSI in breast procedures. Cefazolin sodium prophylaxis was useful in preventing SSI after breast surgery...
  37. ncbi Interrupted or continuous slowly absorbable sutures for closure of primary elective midline abdominal incisions: a multicenter randomized trial (INSECT: ISRCTN24023541)
    Christoph M Seiler
    Study Center of the German Surgical Society, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany
    Ann Surg 249:576-82. 2009
    ..The aim of this study is to compare: (1) interrupted technique with rapidly absorbable sutures and (2) continuous techniques with different slowly absorbable sutures, focusing on the incidence of incisional hernias within 1 year...
  38. ncbi Intranasal mupirocin to prevent postoperative Staphylococcus aureus infections
    Trish M Perl
    University of Iowa Colleges of Medicine and Public Health, Iowa City, USA
    N Engl J Med 346:1871-7. 2002
    ..Treatment with mupirocin ointment can reduce the rate of nasal carriage and may prevent postoperative S. aureus infections...
  39. ncbi Infection of the surgical site after arthroplasty of the hip
    S Ridgeway
    Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    J Bone Joint Surg Br 87:844-50. 2005
    ..MRSA was the most common pathogen to cause SSI in hip arthroplasty, especially in patients undergoing hemiarthroplasty, but coagulase-negative Staph. aureus may be more important in deep infections involving the joint...
  40. ncbi Endoscopic vein harvest: advantages and limitations
    Pramod Bonde
    Department of Cardiac Surgery, Royal Victoria Hospital, Belfast, United Kingdom
    Ann Thorac Surg 77:2076-82. 2004
    ..Endoscopic vein harvest (EVH) attempts to reduce this morbidity and improve patient satisfaction with no compromise in outcome...
  41. ncbi Postoperative complications after vulvectomy and inguinofemoral lymphadenectomy using separate groin incisions
    K N Gaarenstroom
    Department of Gynecology, Leiden University Medical Center, Leiden, The Netherlands
    Int J Gynecol Cancer 13:522-7. 2003
    ..The occurrence of early complications was related to lymphedema. No other risk factors could be identified...
  42. ncbi Safety and outcome of use of nonabsorbable mesh for repair of fascial defects in the presence of open bowel
    Daniel J Geisler
    Section of Colorectal Surgery, Saint Vincent Health Center, Erie, Pennsylvania, USA
    Dis Colon Rectum 46:1118-23. 2003
    ..The purpose of this study was to evaluate the safety and efficacy of nonabsorbable mesh used for hernia repair in the presence of a stoma or at the time of colon resection...
  43. ncbi Endoscopic versus open saphenous vein harvest: the effect on postoperative outcomes
    T Z Hayward
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Thorac Surg 68:2107-10; discussion 2110-1. 1999
    ..The purpose of this study was to objectively compare the two techniques...
  44. ncbi Prolonged antibiotic prophylaxis after cardiovascular surgery and its effect on surgical site infections and antimicrobial resistance
    S Harbarth
    Department of Epidemiology, Harvard School of Public Health, and Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Circulation 101:2916-21. 2000
    ..Despite evidence supporting short antibiotic prophylaxis (ABP), it is still common practice to continue ABP for more than 48 hours after coronary artery bypass graft (CABG) surgery...
  45. ncbi Adverse impact of surgical site infections in English hospitals
    R Coello
    Healthcare Associated Infection and Antimicrobial Resistance Department, Communicable Diseases Surveillance Centre, Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    J Hosp Infect 60:93-103. 2005
    ..04). This study shows that the adverse impact of SSI differs greatly for different categories of surgery, and highlights the importance of measuring the impact for defined categories rather than for all SSIs and all surgical procedures...
  46. ncbi Environmental controls in operating theatres
    S Dharan
    Infection Control Programme, Department of Internal Medicine, University of Geneva Hospitals, Switzerland
    J Hosp Infect 51:79-84. 2002
    ..Environmental bacterial sampling in operating theatres should be limited to investigation of epidemics, validation of protocols, or changes made in materials which could influence the microbial content...
  47. ncbi Outcomes and perioperative hyperglycemia in patients with or without diabetes mellitus undergoing coronary artery bypass grafting
    Carlos A Estrada
    Department of Internal Medicine, The Brody School of Medicine, East Carolina University, Greenville, North Carolina 27858, USA
    Ann Thorac Surg 75:1392-9. 2003
    ..We measured the association between perioperative hyperglycemia and outcomes among patients undergoing coronary artery bypass grafting...
  48. ncbi Obesity and infection
    Matthew E Falagas
    Alfa Institute of Biomedical Sciences, Athens, Greece
    Lancet Infect Dis 6:438-46. 2006
    ..Large prospective studies are required to further define the burden of infectious morbidity and mortality conferred by obesity...
  49. pmc Surgical wound infection as a performance indicator: agreement of common definitions of wound infection in 4773 patients
    A P R Wilson
    Department of Clinical Microbiology, University College London Hospitals, London WC1E 6DB
    BMJ 329:720. 2004
    ..To assess the level of agreement between common definitions of wound infection that might be used as performance indicators...
  50. ncbi The cost of vacuum-assisted closure therapy in treatment of deep sternal wound infection
    Arash Mokhtari
    Department of Cardiothoracic Surgery, Lund University Hospital, Lund, Sweden
    Scand Cardiovasc J 42:85-9. 2008
    ..8 times that for normal, CABG surgery. Promising results have been reported with vacuum-assisted closure (VAC) therapy in patients with DSWI. This study presents the cost of VAC therapy in patients with DSWI after CABG surgery...
  51. ncbi Barrier wound protection decreases surgical site infection in open elective colorectal surgery: a randomized clinical trial
    Kate Reid
    Canberra Hospital, Canberra City, Australian Capital Territory, Australia
    Dis Colon Rectum 53:1374-80. 2010
    ..The aim of this randomized study was to examine the efficacy of barrier retractional wound protection in the prevention of surgical site infections in open, elective colorectal surgery...
  52. ncbi A wound protector shields incision sites from bacterial invasion
    Tetsuya Horiuchi
    Department of Surgery, Minami Wakayama Medical Center, Wakayama, Japan
    Surg Infect (Larchmt) 11:501-3. 2010
    ....
  53. pmc Reduction of surgical site infections after implementation of a bundle of care
    Rogier M P H Crolla
    Department of Surgery, Amphia Hospital, Breda, The Netherlands
    PLoS ONE 7:e44599. 2012
    ..Surgical Site Infections (SSI) are relatively frequent complications after colorectal surgery and are associated with substantial morbidity and mortality...
  54. ncbi Reducing surgical site infection incidence through a network: results from the French ISO-RAISIN surveillance system
    P Astagneau
    Coordinating Centre for Nosocomial Infection Control, Northern Region, Paris, France
    J Hosp Infect 72:127-34. 2009
    ..Active surveillance striving for a benchmark throughout a network is an effective strategy to reduce SSI incidence...
  55. ncbi Prospective comparative study of single dose versus 3-day administration of antimicrobial prophylaxis in minimum incision endoscopic radical prostatectomy
    Mizuaki Sakura
    Department of Urology, Graduate School, Tokyo Medical and Dental University, Tokyo, Japan
    Int J Urol 15:328-31. 2008
    ..We have prospectively reduced AMP and evaluated the occurrence of surgical site infection (SSI) following radical retropubic prostatectomy (RRP) by minimum incision endoscopic surgery (MIES)...
  56. pmc Single-dose versus multiple-dose antibiotic prophylaxis for the surgical treatment of closed fractures
    Gerard P Slobogean
    Department of Orthopaedics, University of British Columbia, Vancouver, BC
    Acta Orthop 81:256-62. 2010
    ..In order to assist clinicians in choosing the optimal prophylaxis strategy, we performed a cost-effectiveness analysis comparing single- and multiple-dose prophylaxis...
  57. ncbi French national program for prevention of healthcare-associated infections and antimicrobial resistance, 1992-2008: positive trends, but perseverance needed
    Jean Carlet
    French National Authority for Health, Haute Autorité Santé, Saint Denis, France
    Infect Control Hosp Epidemiol 30:737-45. 2009
    ..aureus isolates recovered...
  58. ncbi Timing of perioperative antibiotics for cesarean delivery: a metaanalysis
    Maged M Costantine
    Department of Obstetrics and Gynecology, University of Texas Medical Branch, Galveston, TX 77555 0587, USA
    Am J Obstet Gynecol 199:301.e1-6. 2008
    ..The purpose of this study was to summarize the available evidence on timing of perioperative antibiotics for cesarean delivery...
  59. ncbi Surgical site infection in elective operations for colorectal cancer after the application of preventive measures
    Xavier Serra-Aracil
    Unidad de Coloproctologia, Servicio de Cirugia General y Aparato Digestivo, Corporación Sanitaria Parc Taulí, Parc Tauli s n, 08208 Sabadell, Barcelona, Spain
    Arch Surg 146:606-12. 2011
    ..To assess the prevalence of surgical site infection (SSI) after elective operations for colon and rectal cancer after the application of evidence-based preventive measures and to identify risk factors for SSI...
  60. ncbi Non-compliance with recommendations for the practice of antibiotic prophylaxis and risk of surgical site infection: results of a multilevel analysis from the INCISO Surveillance Network
    Katiuska Miliani
    Regional Coordinating Centre for Nosocomial Infection Control C CLIN Paris Nord, Paris, France
    J Antimicrob Chemother 64:1307-15. 2009
    ..The aim of this study was to determine which surgical antibiotic prophylaxis (SAP) practices alter surgical site infection (SSI) risk...
  61. ncbi Vascular surgical site infection: risk factors and preventive measures
    Dennis F Bandyk
    Division of Vascular and Endovascular Surgery, University of South Florida College of Medicine, Tampa, FL 33606, USA
    Semin Vasc Surg 21:119-23. 2008
    ....
  62. ncbi Molecular mechanisms of RIP, an effective inhibitor of chronic infections
    Florencia Lopez-Leban
    Tufts University, Cummings School of Veterinary Medicine, Department of Biomedical Sciences, North Grafton, MA, USA
    Int J Artif Organs 33:582-9. 2010
    ....
  63. ncbi Triclosan-impregnated sutures to decrease surgical site infections: systematic review and meta-analysis of randomized trials
    Wai Keat Chang
    Department of Surgery, South Auckland Clinical School, Middlemore Hospital, University of Auckland, Otahuhu, Auckland, New Zealand
    Ann Surg 255:854-9. 2012
    ..To determine the efficacy and safety of triclosan-impregnated sutures...
  64. ncbi Risk factors for surgical site infections after breast surgery: a systematic review and meta-analysis
    D Q Xue
    Department of Breast Surgery, The Third Affiliated Hospital of Suzhou University, 185 Juqian Road, 213003 Changzhou, China
    Eur J Surg Oncol 38:375-81. 2012
    ..However, studies about risk factors for breast SSIs were still under controversy because of limited data, contradictory results and lack of uniformity...
  65. ncbi Randomized trial of antimicrobial-coated sutures to prevent surgical site infection after breast cancer surgery
    Nia Williams
    Department of Wound Healing and Dermatology, Cardiff University, Cardiff, United Kingdom
    Surg Infect (Larchmt) 12:469-74. 2011
    ....
  66. ncbi Vacuum-assisted closure therapy for patients with infected sternal wounds: a meta-analysis of current evidence
    G Damiani
    Department of Public Health, Universita Cattolica Sacro Cuore, Roma, Italy
    J Plast Reconstr Aesthet Surg 64:1119-23. 2011
    ..18 days in hospital LOS (confidence interval (CI) 95%: 10.82, 3.54), with no significant impact on mortality. Our data provide robust evidence of the effectiveness of VAC therapy...
  67. ncbi Surgical site infections after abdominal closure in colorectal surgery using triclosan-coated absorbable suture (PDS Plus) vs. uncoated sutures (PDS II): a randomized multicenter study
    József Baracs
    Department of Surgery, University of Pecs, Pecs, Hungary
    Surg Infect (Larchmt) 12:483-9. 2011
    ..The main goal of this study was to compare triclosan-coated and uncoated absorbable suture (PDS Plus(®) with PDS II(®)) in elective colorectal operations...
  68. pmc Low infection rates after 34,361 intramedullary nail operations in 55 low- and middle-income countries: validation of the Surgical Implant Generation Network (SIGN) online surgical database
    Sven Young
    Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 82:737-43. 2011
    ..Most operations are reported to the SIGN Online Surgical Database (SOSD). Follow-up has been reported to be low, however. We wanted to examine the pattern of follow-up and to assess whether infection rates could be trusted...
  69. pmc Reduction of surgical site infection using a novel intervention (ROSSINI): study protocol for a randomised controlled trial
    Thomas D Pinkney
    Surgical Registrar, West Midlands Deanery West Midlands Research Collaborative, UK
    Trials 12:217. 2011
    ..Whilst there is some encouraging evidence showing that such devices may lead to a reduction in SSI, there are no controlled trials of sufficient size or quality to support their routine use...
  70. ncbi Microbial pathogenesis of bacterial biofilms: a causative factor of vascular surgical site infection
    Elisabeth Frei
    Division of Vascular and Endovascular Surgery, University of South Florida College of Medicine, Tampa, FL 33606, USA
    Vasc Endovascular Surg 45:688-96. 2011
    ..By understanding the microbial pathogenesis of biofilm formation, strategies to treat and prevent biofilm-mediated infection can be developed and utilized to reduce vascular SSIs...
  71. ncbi Impact of using triclosan-antibacterial sutures on incidence of surgical site infection
    Ibrahim Galal
    Department of Surgery, Cairo University Hospitals, Cairo, Egypt
    Am J Surg 202:133-8. 2011
    ..Surgical site infection is a common complication of surgery. Its morbidities range from delayed healing to systemic sepsis. It has impact on the economy and health care resources...
  72. pmc Nonconcordance with surgical site infection prevention guidelines and rates of surgical site infections for general surgical, neurological, and orthopedic procedures
    Barnaby Young
    Infectious Diseases, Communicable Disease Centre, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433, Republic of Singapore
    Antimicrob Agents Chemother 55:4659-63. 2011
    ..030; 95% CI, 1.018 to 15.96). A strong correlation was identified between the degree of concordance to SSI prevention guidelines and the SSI rate (P = 0.001, Mantel-Haenszel linear-by-linear association chi-square test)...
  73. pmc Interventional studies for preventing surgical site infections in sub-Saharan Africa - A systematic review
    Alexander M Aiken
    London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    Int J Surg 10:242-9. 2012
    ..There is a great need for safe surgical services in sub-Saharan Africa, but a major difficulty of performing surgery in this region is the high risk of post-operative surgical site infection (SSI)...
  74. pmc Treatment outcomes of postoperative mediastinitis in cardiac surgery; negative pressure wound therapy versus conventional treatment
    Hayati Deniz
    Gaziantep University Medical Faculty, Department of Cardiovascular Surgery, Sehitkamil, Gaziantep, Turkey
    J Cardiothorac Surg 7:67. 2012
    ..The aim of the present study is to compare negative pressure wound therapy versus conventional treatment outcomes at postoperative mediastinitis after cardiac surgery...
  75. pmc Adherence to perioperative antibiotic prophylaxis among orthopedic trauma patients
    Kristopher M Lundine
    Division of Orthopaedics, Health Sciences Centre, 3330 Hospital Dr NW, Calgary, Alberta
    Can J Surg 53:367-72. 2010
    ..We also investigated what doses and durations of antibiotics are typically ordered, which patients actually receive antibiotics and factors causing the ordered antibiotic regimen to be altered...
  76. pmc Association between endoscopic vs open vein-graft harvesting and mortality, wound complications, and cardiovascular events in patients undergoing CABG surgery
    Judson B Williams
    Duke Clinical Research Institute, Duke University Medical Center, Durham, NC 27710, USA
    JAMA 308:475-84. 2012
    ..The safety and durability of endoscopic vein graft harvest in coronary artery bypass graft (CABG) surgery has recently been called into question...
  77. ncbi ALEXIS O-Ring wound retractor vs conventional wound protection for the prevention of surgical site infections in colorectal resections(1)
    K P Cheng
    Department of Surgery, University of Malaya Medical Centre, Kuala Lumpur, Malaysia
    Colorectal Dis 14:e346-51. 2012
    ..The aim of this study is to investigate whether ALEXIS wound retractors with reinforced O-rings are superior to conventional wound protection methods in preventing SSIs in colorectal resections...
  78. ncbi Effect of triclosan-coated sutures on the incidence of surgical wound infection after lower limb revascularization surgery: a randomized controlled trial
    Johanna Turtiainen
    Department of Surgery, North Karelia Central Hospital, Tikkamäentie 1, Joensuu, 80210, Finland
    World J Surg 36:2528-34. 2012
    b>Surgical wound infection (SWI) is a common complication after peripheral vascular surgery...
  79. ncbi Prophylactic antibiotics in hip and knee arthroplasty
    John Meehan
    Department of Orthopaedic Surgery, University of California at Davis, 4860 Y Street, Suite 3800, Sacramento, CA 95817, USA
    J Bone Joint Surg Am 91:2480-90. 2009
    ..Hospitals with antibiogram data that reveal high Staphylococcus resistance should consider use of vancomycin as a prophylactic antibiotic...
  80. ncbi Adverse effect of noise in the operating theatre on surgical-site infection
    A Kurmann
    Department of Visceral Surgery and Medicine, University of Neuchatel, Neuchatel, Switzerland
    Br J Surg 98:1021-5. 2011
    ..The aim of this pilot study was to evaluate the noise level in an operating theatre as a possible surrogate marker for intraoperative behaviour, and to detect any correlation between sound level and subsequent surgical-site infection (SSI)...
  81. ncbi Surveillance of surgical-site infections: impact on quality of care and reporting dilemmas
    Pascal Astagneau
    Regional Coordinating Center for Nosocomial Infection Control, France
    Curr Opin Infect Dis 23:306-10. 2010
    ..This review focuses on recent advances in surveillance as a tool for improving healthcare quality performance in surgery...
  82. ncbi A randomized study comparing skin closure in cesarean sections: staples vs subcuticular sutures
    Julie Anne Rousseau
    Department of Obstetrics and Gynecology, Laval University, Quebec, QC, Canada
    Am J Obstet Gynecol 200:265.e1-4. 2009
    ..We sought to compare postoperative pain according to the skin closure method (subcuticular sutures vs staples) after an elective term cesarean section...
  83. ncbi Omental transposition: the final solution for major sternal wound infection
    Kalliopi Athanassiadi
    1st Department of Thoracic Surgery, General Hospital for Chest Diseases, Athens, Greece
    Asian Cardiovasc Thorac Ann 15:200-3. 2007
    ..Radical debridement along with omental flap transposition provides definitive control of the infection in cases of failure of other semi-conservative or surgical interventions. Prognosis depends on the general condition of the patient...
  84. ncbi Surveillance, control, and prevention of surgical site infections in breast cancer surgery: a 5-year experience
    Diana Vilar-Compte
    Department of Infectious Diseases, National Cancer Institute, Tlalpan, Mexico
    Am J Infect Control 37:674-9. 2009
    ..We analyzed variations in surgical site infections (SSIs) during 5 years of a prospective surveillance program and investigated possible contributors to SSIs in a cohort of patients who underwent surgery for breast cancer...
  85. ncbi Administration of cefazolin prior to skin incision is superior to cefazolin at cord clamping in preventing postcesarean infectious morbidity: a randomized, controlled trial
    Scott A Sullivan
    Department of Obstetrics Gynecology, Medical University of South Carolina, Charleston, SC 29425, USA
    Am J Obstet Gynecol 196:455.e1-5. 2007
    ..The objective of the study was to determine whether the administration of cefazolin prior to skin incision was superior to administration at the time of umbilical cord clamping for the prevention of postcesarean infectious morbidity...
  86. pmc Complications of definitive open reduction and internal fixation of pilon fractures of the distal tibia
    Philip A McCann
    Department of Trauma and Orthopaedics, Bristol Royal Infirmary, Bristol, Avon, BS2 8HW, UK
    Int Orthop 35:413-8. 2011
    ..We therefore believe that open reduction and internal fixation of pilon fractures via the direct approach to be a safe technique in the treatment of such devastating injuries...
  87. ncbi Randomized prospective comparison of fosfomycin and cefotiam for prevention of postoperative infection following urological surgery
    Kazuhiro Ishizaka
    Department of Urology, Kanto Central Hospital, 6 25 1 Kamiyoga, Setagaya Ku, Tokyo 158 8531, Japan
    J Infect Chemother 13:324-31. 2007
    ..9% for CTM, with no statistically significant difference. These data show that CTM and FOM are similarly effective in preventing infection following a wide range of urologic surgeries...
  88. pmc Infection in total hip replacement: meta-analysis
    Surendra Senthi
    Department of Orthopaedic Surgery, Middlemore Hospital, South Auckland Clinical School, University of Auckland, Private Bag, 93311, Auckland, New Zealand
    Int Orthop 35:253-60. 2011
    ..The duration of antibiotic therapy remains controversial. There is concern about increasing bacterial resistance especially with the widespread use of vancomycin and ertapenem (carbapenem)...
  89. ncbi Surgical site infections in HIV-infected patients: results from an Italian prospective multicenter observational study
    C M J Drapeau
    2nd Infectious Diseases Division, National Institute for Infectious Diseases, L Spallanzani, Via Portuense 292, 00149, Rome, Italy
    Infection 37:455-60. 2009
    ..The aim of this study was to determine the incidence and the associated risk factors for SSI in HIV-infected patients...
  90. pmc Risk factors for surgical site infection after elective resection of the colon and rectum: a single-center prospective study of 2,809 consecutive patients
    R Tang
    Colorectal Section, Chang Gung Memorial Hospital, Linkou, Taiwan
    Ann Surg 234:181-9. 2001
    ..CONCLUSIONS: In addition to ASA score and surgical wound class, blood transfusion, creation of ostomy, types of operation, use of drainage, sex, and surgeons were important in predicting SSIs after elective colorectal resection...
  91. ncbi Microbiology of surgical site infections complicating breast surgery
    Alyssa D Throckmorton
    Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA
    Surg Infect (Larchmt) 11:355-9. 2010
    ..The aim of this study was to evaluate the results of bacterial cultures of breast SSI sites and antibiotic susceptibility testing to determine the clinical utility of these findings...
  92. ncbi Cost-effectiveness of preoperative nasal mupirocin treatment in preventing surgical site infection in patients undergoing total hip and knee arthroplasty: a cost-effectiveness analysis
    Xan F Courville
    Department of Orthopaedics, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Infect Control Hosp Epidemiol 33:152-9. 2012
    ..To perform a cost-effectiveness analysis to evaluate preoperative use of mupirocin in patients with total joint arthroplasty (TJA)...
  93. ncbi Accelerated treatment of postpneumonectomy empyema: a binational long-term study
    Didier Schneiter
    Thoracic Surgery, University Hospital Zurich, Zurich, Switzerland
    J Thorac Cardiovasc Surg 136:179-85. 2008
    ..Postpneumonectomy empyema remains a clinical challenge. We proposed an accelerated therapy without an open chest window 5 years ago. This concept was evaluated on a larger scale in 2 centers in 2 different countries...
  94. ncbi Supplemental perioperative oxygen and the risk of surgical wound infection: a randomized controlled trial
    F Javier Belda
    Department of Anesthesiology and Critical Care, Hospital Clinico Universitario, Valencia, Spain
    JAMA 294:2035-42. 2005
    Supplemental perioperative oxygen has been variously reported to halve or double the risk of surgical wound infection.
  95. ncbi Does reoperation predispose to postoperative wound infection in women undergoing operation for breast cancer?
    Cam Ly Tran
    Department of Surgery, Kaiser Permanente Medical Center, Los Angeles, California 90027, USA
    Am Surg 69:852-6. 2003
    ..The incidence of wound infection is increased with reoperation after operative biopsy compared to operation after core biopsy and is further increased when the initial biopsy involved lymph node dissection...
  96. ncbi Updated recommendations for control of surgical site infections
    J Wesley Alexander
    University of Cincinnati College of Medicine, Department of Surgery, Cincinnati, Ohio 45267, USA
    Ann Surg 253:1082-93. 2011
    ..The objective of this study is to provide updated guidelines for the prevention of surgical wound infections based upon review and interpretation of the current and past literature...
  97. pmc Antibiotic pharmacodynamics in surgical prophylaxis: an association between intraoperative antibiotic concentrations and efficacy
    Sheryl A Zelenitsky
    Faculty of Pharmacy, University of Manitoba, Winnipeg, Manitoba, Canada
    Antimicrob Agents Chemother 46:3026-30. 2002
    ....
  98. ncbi Hospitals in Europe Link for Infection Control through Surveillance (HELICS). Inter-country comparison of rates of surgical site infection--opportunities and limitations
    J Wilson
    Healthcare Associated Infection and Antimicrobial Resistance Department, Centre for Infection, Health Protection Agency, London, UK
    J Hosp Infect 65:165-70. 2007
    ..This rich dataset provides a unique opportunity to explore variation in rates of SSI and improve understanding of factors that impact on inter-country comparisons...
  99. ncbi Comparison of single versus multiple doses of antibiotic prophylaxis in reducing post-elective Caesarean section infectious morbidity
    A Shakya
    Tribhuvan University Teaching Hospital, Kathmandu, Nepal
    Kathmandu Univ Med J (KUMJ) 8:179-84. 2010
    ..Puerperal sepsis is frequently in Caesarean section. Antibiotic prophylaxis may have significant impact in reduction of infections and thus the need to study its role in sepsis prevention systematically...
  100. pmc Systematic review and cost analysis comparing use of chlorhexidine with use of iodine for preoperative skin antisepsis to prevent surgical site infection
    Ingi Lee
    Divisions of Infectious Diseases, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Infect Control Hosp Epidemiol 31:1219-29. 2010
    ..To compare use of chlorhexidine with use of iodine for preoperative skin antisepsis with respect to effectiveness in preventing surgical site infections (SSIs) and cost...
  101. ncbi Effect of a change in policy regarding the timing of prophylactic antibiotics on the rate of postcesarean delivery surgical-site infections
    Anjali J Kaimal
    Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA
    Am J Obstet Gynecol 199:310.e1-5. 2008
    ..The purpose of this study was to examine the effect of a change in policy regarding the timing of antibiotic administration on the rates of postcesarean delivery surgical-site infections (SSI)...

Research Grants30

  1. Development of Infection-Resistant Suture Materials
    Matthew Phaneuf; Fiscal Year: 2007
    ..infection rates in conjunction with the costs to treat these patients (an average $2,300/episode), surgical wound infection results in an annual cost to the healthcare system of greater than $5 billion...
  2. A novel Structure Based Vaccine for staphylococcal alpha hemolysin
    Rajan P Adhikari; Fiscal Year: 2013
    ..models of infection: pneumonia, subcutaneous abscess model representing SSTI, bacteremia/sepsis, and surgical wound infection. This proposal is a collaborative effort between IBT and Dr...
  3. Development of Infection-Resistant Suture Materials
    Matthew Phaneuf; Fiscal Year: 2004
    ..on the current infection rates in conjunction with the costs to treat these patients ($2,300/episode), surgical wound infection results in an annual cost to the healthcare system of greater than $750 million...
  4. Host Response in S. aureus Infections: Role of T cells
    Arthur Tzianabos; Fiscal Year: 2006
    ..This hypothesis will be tested in staphylococcal animal models of subcutaneous abscess formation and surgical wound infection. These models are clinically relevant, low-inoculum murine models of staphylococcal disease that mimic ..
  5. Nitrous Oxide and Wound Infections
    Ozan Akca; Fiscal Year: 2006
    ..We anticipate showing that substituting nitrous oxide for nitrogen reduces the incidence of surgical wound infection. Confirming our hypothesis would thus allow clinicians to make a minor modification in anesthetic ..
  6. Incidence & Outcomes of SSI After Breast Cancer Surgery
    Margaret Olsen; Fiscal Year: 2008
    ....
  7. Molecular Analysis of Scarless Fetal Wound Healing
    Sandeep Kathju; Fiscal Year: 2007
    ..With these complementary approaches we hope to thereby arrive at a broad understanding of the gene patterns controlling both fetal and adult wound healing, and identify gene products/pathways critical to both. ..
  8. Hospital-Acquired Infections in the Elderly
    Keith Kaye; Fiscal Year: 2008
    ..The risk factor identified for SSI and MDRB and the impact of SSI and MDRB on health outcomes will be used to design and implement future preventive interventions. ..
  9. Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB Infections
    Lisa Saiman; Fiscal Year: 2009
    ..Carefully conducted observational studies and clinically relevant in vitro antimicrobial susceptibility testing, hold the greatest promise to improve the treatment of patients infected with mutidrug-resistant organisms. ..
  10. Catheter Dwell Time and Risk of Bloodstream Infections in Hospitalized Neonates
    Aaron M Milstone; Fiscal Year: 2011
    ..This project will help to develop evidence-based strategies to prevent bloodstream infections among vulnerable infants hospitalized in the neonatal intensive care unit. ..
  11. Mechanisms By Which Endothelium Cells Sense Changes in Hemodynamics
    Bauer Sumpio; Fiscal Year: 2007
    ..4. Assess egr-1 and sp1 binding in MT1-MMP and PDGF-B promoters under mechanical stress 5.Assess the functional relevance of egr-1 in a low flow carotid model using an egr-1 knock-out mouse. ..
  12. Impact of Gender on Infected Hospitalized Patients
    Robert Sawyer; Fiscal Year: 2006
    ..Data obtained from this research will be used to design interventional studies utilizing hormonal manipulation, i. e., replacement or blockade, to improve outcomes from otherwise lethal infectious diseases. ..
  13. Resistant E.coli in Humans and Poultry
    James Johnson; Fiscal Year: 2005
    ..Does the research address a current and compelling problem of antimicrobial resistance that is of high public health importance and for which research is needed? [yes]. ..
  14. Vascular Access in Hemodialysis Patients
    Michael Allon; Fiscal Year: 2005
    ..The applicant will assist the trainees in acquiring the conceptual skills, research experience, and motivation required to pursue a successful career in Academic Nephrology. ..
  15. HEMODIALYSIS VASCULAR ACCESS CLINICAL TRIALS CONSORTIUM
    Michael Allon; Fiscal Year: 2007
    ..The primary endpoint will be fistula thrombosis within 6 weeks, and the secondary endpoint will be the ability to use the fistula successfully for dialysis within 6 months. ..
  16. FUNDAMENTALS OF SURGICAL RESEARCH COURSE
    Henri Ford; Fiscal Year: 2008
    ..Therefore, promoting, educating and training the young surgical investigator in the responsible conduct of research is an essential component of the Fundamentals of Surgical Research Course. ..
  17. Outcomes of ICU Working Conditions
    Patricia Stone; Fiscal Year: 2003
    ..In addition, obtaining NNIS and Medicare data creates an opportunity to explore the sensitivity and specificity of identifying NI through claims data. ..
  18. THE SIGNIFICANCE OF FUNGURIA IN HOSPITALIZED PATIENTS
    Loren Miller; Fiscal Year: 2004
    ....
  19. UNDERSTANDING THE PATHOGENESIS OF STAPHYLOCOCCUS AUREUS
    Vance Fowler; Fiscal Year: 2003
    ..Accomplishing the aims of this proposal will contribute to improved clinical management of patients with S. aureus bacteremia, and will add to the understanding of S. aureus virulence factors. ..
  20. Effect of leukoreduction on infection risk in trauma
    Avery Nathens; Fiscal Year: 2004
    ..abstract_text> ..
  21. Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB Infections
    Lisa Maragakis; Fiscal Year: 2009
    ..This research is designed to better understand how providers use information from various microbiology laboratory testing methods to choose treatments and to identify strategies that lead to the best patient outcomes. ..
  22. UW/USM Chronic Prostatitis CRC
    JOHN KRIEGER; Fiscal Year: 2007
    ..Potential outcomes include: symptom indexes (e.g., the NIH-CPSI), urodynamics and inflammation. ..
  23. Does NO mediate clinical anti-VEGF vascular effects
    Herbert Hurwitz; Fiscal Year: 2004
    ..However, to allow for potential clinical benefit, patients will be permitted to receive ongoing anti-VEGF therapy as deemed appropriate by their physician. ..
  24. Permeability Changes in Small Bowel Allograft Rejection
    Jonathan Fryer; Fiscal Year: 2006
    ....
  25. Prevention of Healthcare-Associated Drug-Resistant GNR
    Lisa Maragakis; Fiscal Year: 2006
    ..Maragakis with the skills she needs to develop into an independent clinical investigator in epidemiologic research for the prevention of healthcare-associated infections. ..
  26. Prospective evaluation of immediate temporized implants
    Michael Block; Fiscal Year: 2007
    ..Standardized hard and soft tissue data will be collected preextraction as baseline, and then prospectively for at least two years in this trial, to compare and contrast the methods. ..
  27. Hypocaloric Nutrition and Outcomes in Critically 111 Patients
    ROSEMARIE METZGER; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  28. Anti-Selectin Blocker for Liver Ischemic Injury
    LUIS TOLEDO PEREYRA; Fiscal Year: 2006
    ..Treatment with TCB-1269 will enhance the quality of life of millions of patients suffering from the large number of maladies associated with ischemia/reperfusion ischemic maladies. [unreadable] [unreadable]..
  29. THE CLOUD ADULT
    Robert Sherertz; Fiscal Year: 2003
    ..aureus associated with a viral URI, have been shown to cause outbreaks. Understanding the "cloud phenomenon" may facilitate S.aureus outbreak prevention and possibly the transmission of other pathogens, as well. ..
  30. GENETIC TESTING AND THE ECONOMICS OF LIFE INSURANCE
    David Asch; Fiscal Year: 2002
    ..abstract_text> ..