infectious pregnancy complications

Summary

Summary: The co-occurrence of pregnancy and an INFECTION. The infection may precede or follow FERTILIZATION.

Top Publications

  1. pmc Impact of malaria during pregnancy on low birth weight in sub-Saharan Africa
    Helen L Guyatt
    Kenya Medical Research Institute Wellcome Trust Collaborative Programme, P O Box 43640, Nairobi, Kenya
    Clin Microbiol Rev 17:760-9, table of contents. 2004
  2. ncbi Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission
    Ellen R Cooper
    Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston University School of Medicine, 774 Albany Street, Suite 506, Boston, MA 02118, U S A
    J Acquir Immune Defic Syndr 29:484-94. 2002
  3. ncbi Association between bacterial vaginosis and preterm delivery of a low-birth-weight infant. The Vaginal Infections and Prematurity Study Group
    S L Hillier
    University of Washington, Seattle, USA
    N Engl J Med 333:1737-42. 1995
  4. ncbi Passive immunization during pregnancy for congenital cytomegalovirus infection
    Giovanni Nigro
    Department of Pediatrics, La Sapienza University, Rome
    N Engl J Med 353:1350-62. 2005
  5. pmc Diagnosis and management of human cytomegalovirus infection in the mother, fetus, and newborn infant
    Maria Grazia Revello
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Clin Microbiol Rev 15:680-715. 2002
  6. pmc Emerging infections and pregnancy
    Denise J Jamieson
    Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Emerg Infect Dis 12:1638-43. 2006
  7. ncbi Syphilis in pregnancy in Tanzania. II. The effectiveness of antenatal syphilis screening and single-dose benzathine penicillin treatment for the prevention of adverse pregnancy outcomes
    Deborah Watson-Jones
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Infect Dis 186:948-57. 2002
  8. ncbi Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study
    Ibou Thior
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Mass 02115, USA
    JAMA 296:794-805. 2006
  9. ncbi The burden of co-infection with human immunodeficiency virus type 1 and malaria in pregnant women in sub-saharan Africa
    Feiko O Ter Kuile
    Child and Reproductive Health Group, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
    Am J Trop Med Hyg 71:41-54. 2004
  10. ncbi Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis
    Marie Louise Newell
    Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London WC1N 1EH, UK
    Lancet 364:1236-43. 2004

Research Grants

Detail Information

Publications294 found, 100 shown here

  1. pmc Impact of malaria during pregnancy on low birth weight in sub-Saharan Africa
    Helen L Guyatt
    Kenya Medical Research Institute Wellcome Trust Collaborative Programme, P O Box 43640, Nairobi, Kenya
    Clin Microbiol Rev 17:760-9, table of contents. 2004
    ..These estimates imply that around 100,000 infant deaths each year could be due to LBW caused by malaria during pregnancy in areas of malaria endemicity in Africa...
  2. ncbi Combination antiretroviral strategies for the treatment of pregnant HIV-1-infected women and prevention of perinatal HIV-1 transmission
    Ellen R Cooper
    Maxwell Finland Laboratory for Infectious Diseases, Boston Medical Center, Boston University School of Medicine, 774 Albany Street, Suite 506, Boston, MA 02118, U S A
    J Acquir Immune Defic Syndr 29:484-94. 2002
    ..The Women and Infants Transmission Study is a prospective natural history study that has been enrolling HIV-1-infected pregnant women and their infants since 1989...
  3. ncbi Association between bacterial vaginosis and preterm delivery of a low-birth-weight infant. The Vaginal Infections and Prematurity Study Group
    S L Hillier
    University of Washington, Seattle, USA
    N Engl J Med 333:1737-42. 1995
    ..1; 95 percent confidence interval, 1.5 to 3.0). CONCLUSIONS. Bacterial vaginosis was associated with the preterm delivery of low-birth-weight infants independently of other recognized risk factors...
  4. ncbi Passive immunization during pregnancy for congenital cytomegalovirus infection
    Giovanni Nigro
    Department of Pediatrics, La Sapienza University, Rome
    N Engl J Med 353:1350-62. 2005
    ..Currently, there is no effective intervention for a primary cytomegalovirus (CMV) infection during pregnancy...
  5. pmc Diagnosis and management of human cytomegalovirus infection in the mother, fetus, and newborn infant
    Maria Grazia Revello
    Servizio di Virologia, IRCCS Policlinico San Matteo, 27100 Pavia, Italy
    Clin Microbiol Rev 15:680-715. 2002
    ....
  6. pmc Emerging infections and pregnancy
    Denise J Jamieson
    Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Emerg Infect Dis 12:1638-43. 2006
    ..Pregnant women's altered response to infectious diseases should be considered when planning a response to emerging infectious disease threats...
  7. ncbi Syphilis in pregnancy in Tanzania. II. The effectiveness of antenatal syphilis screening and single-dose benzathine penicillin treatment for the prevention of adverse pregnancy outcomes
    Deborah Watson-Jones
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, United Kingdom
    J Infect Dis 186:948-57. 2002
    ..4-1.4) or low-titer active syphilis (OR, 0.95; 95% CI, 0.6-1.5), compared with seronegative women. Single-dose treatment is effective in preventing adverse pregnancy outcomes attributable to maternal syphilis...
  8. ncbi Breastfeeding plus infant zidovudine prophylaxis for 6 months vs formula feeding plus infant zidovudine for 1 month to reduce mother-to-child HIV transmission in Botswana: a randomized trial: the Mashi Study
    Ibou Thior
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, Boston, Mass 02115, USA
    JAMA 296:794-805. 2006
    ..Postnatal transmission of human immunodeficiency virus-1 (HIV) via breastfeeding reverses gains achieved by perinatal antiretroviral interventions...
  9. ncbi The burden of co-infection with human immunodeficiency virus type 1 and malaria in pregnant women in sub-saharan Africa
    Feiko O Ter Kuile
    Child and Reproductive Health Group, Liverpool School of Tropical Medicine, Liverpool, United Kingdom
    Am J Trop Med Hyg 71:41-54. 2004
    ..There is a clear need to strengthen the deployment of existing malaria and HIV prevention and intervention measures for pregnant women...
  10. ncbi Mortality of infected and uninfected infants born to HIV-infected mothers in Africa: a pooled analysis
    Marie Louise Newell
    Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, London WC1N 1EH, UK
    Lancet 364:1236-43. 2004
    ..With individual data from seven randomised mother-to-child transmission (MTCT) intervention trials, we estimate mortality in African children born to HIV-infected mothers and analyse selected risk factors...
  11. ncbi Cost-effectiveness of nevirapine to prevent mother-to-child HIV transmission in eight African countries
    Michael D Sweat
    Department of International Health, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland 21205, USA
    AIDS 18:1661-71. 2004
    ..Most attention has been given to preventing vertical transmission based on analysis showing nevirapine to be inexpensive and cost-effective...
  12. ncbi Vulnerability of women in an African setting: lessons for mother-to-child HIV transmission prevention programmes
    Philippe Gaillard
    International Centre for Reproductive Health, University of Ghent, Ghent, Belgium
    AIDS 16:937-9. 2002
    ..To increase the uptake of interventions to reduce perinatal HIV transmission safely, we recommend the involvement of partners in HIV testing. In addition, the counselling of women has to address methods and skills to deal with violence...
  13. ncbi Mothers infected with HIV
    James Mcintyre
    Perinatal HIV Research Unit, University of the Witwatersrand, Johannesburg, South Africa
    Br Med Bull 67:127-35. 2003
    ..Without such efforts and increased HIV prevention, the gains achieved by safe motherhood programmes will be lost in the future...
  14. ncbi Correlates of mother-to-child human immunodeficiency virus type 1 (HIV-1) transmission: association with maternal plasma HIV-1 RNA load, genital HIV-1 DNA shedding, and breast infections
    G C John
    Department of Medicine, University of Washington, Seattle, WA, USA
    J Infect Dis 183:206-212. 2001
    ..Use of methods that decrease infant exposure to HIV-1 in maternal genital secretions or breast milk may enhance currently recommended perinatal HIV-1 interventions...
  15. pmc Maternal antibodies enhance or prevent cytomegalovirus infection in the placenta by neonatal Fc receptor-mediated transcytosis
    Ekaterina Maidji
    Department of Cell and Tissue Biology, School of Dentistry, University of California San Francisco, 513 Parnassus, San Francisco, San Francisco, CA 94143 0512, USA
    Am J Pathol 168:1210-26. 2006
    ..These findings could explain the efficacy of hyperimmune IgG for treatment of primary CMV infection during gestation and support vaccination...
  16. pmc An autopsy study of maternal mortality in Mozambique: the contribution of infectious diseases
    Clara Menendez
    Barcelona Center for International Health Research CRESIB and Department of Pathology, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer IDIBAPS, Universitat de Barcelona, Spain
    PLoS Med 5:e44. 2008
    ..The aim of this study was to accurately describe the causes of maternal death in order to contribute to its reduction, in one of the regions of the world with the highest maternal mortality ratios...
  17. ncbi Pregnancy outcome following infections by coxsackie, echo, measles, mumps, hepatitis, polio and encephalitis viruses
    Asher Ornoy
    The Hebrew University Hadassah Medical School and Jerusalem Institute of Child Development, Israeli Ministry of Health, Jerusalem
    Reprod Toxicol 21:446-57. 2006
    ..There is no evidence that immunization in pregnancy against these diseases (with attenuated viruses) may adversely affect pregnancy outcome...
  18. pmc Comparison of the diagnostic accuracy of a rapid immunochromatographic test and the rapid plasma reagin test for antenatal syphilis screening in Mozambique
    Pablo J Montoya
    Health Alliance International, Maputo, Mozambique
    Bull World Health Organ 84:97-104. 2006
    ....
  19. ncbi Voluntary counseling and HIV testing for pregnant women in the Kassena-Nankana district of northern Ghana: is couple counseling the way forward?
    Frank Baiden
    Navrongo Health Research Center, Navrongo, Ghana
    AIDS Care 17:648-57. 2005
    ..Couple counseling facilitated through couple-friendly ANC services should be explored as strategy for the intended VCT program in this district...
  20. ncbi Characteristics of HIV type 1 (HIV-1) glycoprotein 120 env sequences in mother-infant pairs infected with HIV-1 subtype CRF01_AE
    Tanawan Samleerat
    Faculty of Associated Medical Sciences, Chiang Mai University, Thailand
    J Infect Dis 198:868-76. 2008
    ..This finding was particularly significant for the PNGS at positions N301 and N384...
  21. ncbi Placental infection with human papillomavirus is associated with spontaneous preterm delivery
    L M Gomez
    Center for Research on Reproduction and Women s Health, University of Pennsylvania School of Medicine, 2000 Courtyard Building, 3400 Spruce Street, Philadelphia, PA 19104, USA
    Hum Reprod 23:709-15. 2008
    ..We sought to determine if human papillomavirus (HPV) infection of extravillous trophoblast cells reduces cell invasion and if placental infection is associated with adverse reproductive outcomes attributed to placental dysfunction...
  22. pmc Modelling the cost-effectiveness of introducing rapid syphilis tests into an antenatal syphilis screening programme in Mwanza, Tanzania
    P Vickerman
    London School of Hygiene and Tropical Medicine, Keppel Street, London, WC1E 7HT, UK
    Sex Transm Infect 82:v38-43. 2006
    ..This analysis estimates the relative cost-effectiveness of using these POC tests in the Mwanza syphilis screening intervention...
  23. ncbi Hearing loss in children with congenital cytomegalovirus infection born to mothers with preexisting immunity
    Shannon A Ross
    Department of Pediatrics, University of Alabama at Birmingham, 35233, USA
    J Pediatr 148:332-6. 2006
    ..To define hearing outcomes in children with congenital cytomegalovirus (CMV) infection born to mothers with non-primary CMV infection...
  24. pmc Antenatal couple counseling increases uptake of interventions to prevent HIV-1 transmission
    Carey Farquhar
    Department of Medicine, University of Washington, Seattle, WA 98104 249, USA
    J Acquir Immune Defic Syndr 37:1620-6. 2004
    ..004). Partner participation in VCT and couple counseling increased uptake of nevirapine and formula feeding. Antenatal couple counseling may be a useful strategy to promote HIV-1 prevention interventions...
  25. pmc High-risk human papillomavirus clearance in pregnant women: trends for lower clearance during pregnancy with a catch-up postpartum
    M A E Nobbenhuis
    Department of Pathology, Vrije Universiteit Medical Center, PO Box 7057, 1007 MB, Amsterdam, The Netherlands
    Br J Cancer 87:75-80. 2002
    ..3 (0.8-13.7) and 4.6 (1.6-12.8), respectively). These results suggest a lowered immune-response against human papilloma virus during the first two trimesters of pregnancy with a catch-up postpartum...
  26. pmc Sexually transmitted infections in pregnancy: prevalence, impact on pregnancy outcomes, and approach to treatment in developing countries
    S Mullick
    The Population Council, Frontiers in Reproductive Health, Hyde Park Lane Manor, EG001 Edinburgh Gate, Box 411744, Craighall 2024, Johannesburg, South Africa
    Sex Transm Infect 81:294-302. 2005
    ..This review examines the prevalence and impact on pregnancy outcome of STIs in developing countries and recommends approaches to management of STIs in pregnancy for resource poor settings...
  27. ncbi Microbial invasion and cytokine response in amniotic fluid in a Swedish population of women with preterm prelabor rupture of membranes
    Bo Jacobsson
    Perinatal Center, Department of Obstetrics and Gynecology, Institute for the Health of Women and Children, Sahlgrenska University Hospital, Goteborg, Sweden
    Acta Obstet Gynecol Scand 82:423-31. 2003
    ....
  28. pmc Intimate partner violence against women in eastern Uganda: implications for HIV prevention
    Charles A S Karamagi
    Department of Paediatrics and Child Health, Makerere University, Kampala, Uganda
    BMC Public Health 6:284. 2006
    ....
  29. ncbi From effectiveness to impact: contraception as an HIV prevention intervention
    R Wilcher
    Family Health International, P O Box 13950, Research Triangle Park, NC 27709, USA
    Sex Transm Infect 84:ii54-60. 2008
    ..This paper reviews international, country and service delivery level opportunities for and obstacles to translating contraceptive efficacy into interventions that will have an impact on the effectiveness of HIV prevention...
  30. ncbi Effect of pregnancy on HIV disease progression and survival among women in rural Uganda
    Van der Paal Lieve
    MRC UVRI Uganda Research Unit on AIDS, Entebbe, Uganda
    Trop Med Int Health 12:920-8. 2007
    ..To investigate the effect of pregnancy on HIV disease progression and survival among HIV-infected women in rural Uganda, prior to the introduction of anti-retroviral therapy (ART)...
  31. ncbi The importance of prenatal exposures on the development of allergic disease: a birth cohort study using the West Midlands General Practice Database
    Tricia M McKeever
    Division of Respiratory Medicine, University of Nottingham, Nottingham, United Kingdom
    Am J Respir Crit Care Med 166:827-32. 2002
    ..Our findings suggest that exposure to antibiotics and to infections in utero is a potentially important risk factor in the development of allergic disease...
  32. pmc Economic and programmatic aspects of congenital syphilis prevention
    George Schmid
    Research Scientist, Department of HIV AIDS, World Health Organization, 20 Avenue Appia, Geneva 27, Switzerland
    Bull World Health Organ 82:402-9. 2004
    ..The prevention of congenital syphilis should be a global priority; international agencies and national programmes should be committed to improving antenatal care (ANC) services including syphilis detection and prevention...
  33. ncbi Time to undetectable viral load after highly active antiretroviral therapy initiation among HIV-infected pregnant women
    Deven Patel
    Clin Infect Dis 44:1647-56. 2007
    ....
  34. ncbi Experimental infection of pregnant ewes with bovine viral diarrhea virus type-2 (BVDV-2): effects on the pregnancy and fetus
    C F Scherer
    , Universidade Federal de Santa Maria (UFSM, 97105-900, RS, Santa Maria, Brazil
    Vet Microbiol 79:285-99. 2001
    ..These features make this species an attractive animal model for studying the pathogenesis of congenital BVDV-2 infection...
  35. ncbi HIV transmission through breastfeeding: a study in Malawi
    P G Miotti
    Department of Epidemiology, Johns Hopkins School of Hygiene and Public Health, Baltimore, MD, USA
    JAMA 282:744-9. 1999
    ..Understanding the risk of human immunodeficiency virus (HIV) transmission through breastfeeding is essential for advising HIV-infected mothers and formulating public health policy recommendations...
  36. ncbi Contraception to prevent HIV-positive births: current contribution and potential cost savings in PEPFAR countries
    H W Reynolds
    Family Health International, P O Box 13950, Research Triangle Park, NC 27709, USA
    Sex Transm Infect 84:ii49-53. 2008
    ....
  37. ncbi Highly active antiretroviral therapy started during pregnancy or postpartum suppresses HIV-1 RNA, but not DNA, in breast milk
    Roger L Shapiro
    Department of Immunology and Infectious Diseases, Harvard School of Public Health, and Division of Infectious Diseases, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Infect Dis 192:713-9. 2005
    ..The ability of highly active antiretroviral therapy (HAART) to reduce human immunodeficiency virus type 1 (HIV-1) RNA and DNA in breast milk has not been described...
  38. pmc Pandemic influenza and pregnant women
    Sonja A Rasmussen
    National Center of Birth Defects and Developmental Disabilities, Centers for Disease Control and Prevention, 1600 Clifton Road, Atlanta, GA 30333, USA
    Emerg Infect Dis 14:95-100. 2008
    ..Finally, healthcare facilities need to develop plans to minimize exposure of pregnant women to ill persons, while ensuring that women receive necessary care...
  39. ncbi Antiretroviral therapy and premature delivery in diagnosed HIV-infected women in the United Kingdom and Ireland
    Claire L Townsend
    Centre for Paediatric Epidemiology and Biostatistics, Institute of Child Health, University College London, London, UK
    AIDS 21:1019-26. 2007
    ..To explore the association between antiretroviral therapy in pregnancy and premature delivery, birthweight, stillbirth and neonatal mortality, in pregnancies in HIV-infected women delivering between 1990 and 2005...
  40. ncbi Antiretroviral therapy in pregnant women with advanced HIV disease and pregnancy outcomes in Abidjan, Côte d'Ivoire
    Didier K Ekouevi
    ANRS 1201 1202 DITRAME PLUS Project, PACCI Collaboration, Abidjan, Cote d Ivoire, France
    AIDS 22:1815-20. 2008
    ..Pregnancy outcomes in women receiving highly active antiretroviral treatment (HAART) in Africa are not well described...
  41. ncbi Diagnosis of Plasmodium falciparum malaria in pregnancy in sub-Saharan Africa: the challenges and public health implications
    C J Uneke
    Department of Medical Microbiology Parasitology, Faculty of Clinical Medicine, Ebonyi State University, PMB 053 Abakaliki, Nigeria
    Parasitol Res 102:333-42. 2008
    ..Increased allocation of resources to development and application of accurate diagnostics will improve malaria diagnosis in pregnancy...
  42. ncbi Is antiretroviral therapy during pregnancy associated with an increased risk of preterm delivery, low birth weight, or stillbirth?
    Amanda M Cotter
    Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of Miami, Miami, Florida 33101, USA
    J Infect Dis 193:1195-201. 2006
    ..Our objective was to investigate whether antiretroviral therapy was associated with adverse pregnancy outcome at a single site...
  43. ncbi A randomized trial of multivitamin supplements and HIV disease progression and mortality
    Wafaie W Fawzi
    Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
    N Engl J Med 351:23-32. 2004
    ..Results from observational studies suggest that micronutrient status is a determinant of the progression of human immunodeficiency virus (HIV) disease...
  44. ncbi Approaches for scaling up human immunodeficiency virus testing and counseling in prevention of mother-to-child human immunodeficiency virus transmission settings in resource-limited countries
    Omotayo O Bolu
    Centers for Disease Control and Prevention, National Center for HIV, Hepatitis, STD, and TB Prevention, Global AIDS Program, Prevention of Mother to Child HIV Transmission Team, Atlanta, GA 30333, USA
    Am J Obstet Gynecol 197:S83-9. 2007
    ..This paper will review best practices needed for expansion of testing and counseling in PMTCT settings in resource-limited countries...
  45. ncbi Influenza and pneumonia in pregnancy
    Vanessa R Laibl
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390 9032, USA
    Clin Perinatol 32:727-38. 2005
    ..Pregnant patients who have either of these conditions require a higher level of surveillance and intervention...
  46. ncbi Prevention of mother-to-child HIV transmission in resource-poor countries: translating research into policy and practice
    K M De Cock
    Division of HIV AIDS Prevention Surveillance and Epidemiology, National Center for HIV, STD and TB Prevention, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    JAMA 283:1175-82. 2000
    ..Successful implementation of available perinatal HIV interventions could substantially improve global child survival...
  47. pmc Effect of a syphilis control programme on pregnancy outcome in Nairobi, Kenya
    M Temmerman
    Department of Obstetrics and Gynaecology, University of Ghent, Belgium
    Sex Transm Infect 76:117-21. 2000
    ..To assess the impact of a syphilis control programme of pregnant women on pregnancy outcome in Kenya...
  48. ncbi Antenatal syphilis in sub-Saharan Africa: missed opportunities for mortality reduction
    S Gloyd
    Department of Health Services, Box 357660, University of Washington School of Public Health and Community Medicine, Seattle, WA 98195, USA
    Health Policy Plan 16:29-34. 2001
    ..DISCUSSION: Syphilis testing and treatment is a cost-effective intervention that deserves much greater attention, particularly in sub-Saharan Africa and other countries where syphilis infection is high...
  49. ncbi Voluntary counseling and testing for couples: a high-leverage intervention for HIV/AIDS prevention in sub-Saharan Africa
    T M Painter
    Centers for Disease Control and Prevention, National Center for HIV, STD and TB Prevention, Division of HIV AIDS Prevention Surveillance and Epidemiology, Atlanta, GA 30333, USA
    Soc Sci Med 53:1397-411. 2001
    ..It also identifies areas where applied social/behavioral research is needed to improve knowledge about how couples in sub-Saharan Africa deal with the risks of HIV infection...
  50. ncbi Challenges in the concurrent management of malaria and HIV in pregnancy in sub-Saharan Africa
    Paula E Brentlinger
    Department of Health Services, School of Public Health and Community Medicine, University of Washington, Seattle, Washington 98195 7660, USA
    Lancet Infect Dis 6:100-11. 2006
    ....
  51. pmc Modelling HIV/AIDS epidemics in Botswana and India: impact of interventions to prevent transmission
    Nico J D Nagelkerke
    Department of Public Health, Erasmus University Rotterdam, The Netherlands
    Bull World Health Organ 80:89-96. 2002
    ..To describe a dynamic compartmental simulation model for Botswana and India, developed to identify the best strategies for preventing spread of HIV/AIDS...
  52. pmc Listeria monocytogenes traffics from maternal organs to the placenta and back
    Anna I Bakardjiev
    Department of Molecular and Cell Biology, University of California Berkeley, Berkeley, California, USA
    PLoS Pathog 2:e66. 2006
    ..Once colonized, the placenta becomes a nidus of infection resulting in massive reseeding of maternal organs, where L. monocytogenes cannot be cleared until trafficking is interrupted by expulsion of the infected placental tissues...
  53. ncbi Growth of Listeria monocytogenes in the guinea pig placenta and role of cell-to-cell spread in fetal infection
    Anna I Bakardjiev
    Department of Molecular and Cell Biology, University of California, Berkeley, California 94720 3202, USA
    J Infect Dis 191:1889-97. 2005
    ..We concluded that cell-to-cell spread facilitates maternal-to-fetal transmission. Furthermore, the placenta provides a protective niche for growth of L. monocytogenes...
  54. pmc Field efficacy of zidovudine, lamivudine and single-dose nevirapine to prevent peripartum HIV transmission
    Francois Dabis
    Unité INSERM 593, Institut de Santé Publique, Epidémiologie et Développement ISPED, Universite Victor Segalen, 146 rue Leo Saignat, 33076 Bordeaux, France
    AIDS 19:309-18. 2005
    ..We evaluated the 6-week field efficacy of two more PMTCT drug combinations...
  55. pmc Persistence of nevirapine-resistant HIV-1 in women after single-dose nevirapine therapy for prevention of maternal-to-fetal HIV-1 transmission
    S Palmer
    HIV Drug Resistance Program, National Cancer Institute, National Institutes of Health, Frederick, MD 21702 1201, USA
    Proc Natl Acad Sci U S A 103:7094-9. 2006
    ..These findings highlight the urgent need for studies assessing the impact of sdNVP on the efficacy of subsequent antiretroviral therapy containing NVP or other nonnucleoside reverse transcriptase inhibitors...
  56. pmc Impact of influenza exposure on rates of hospital admissions and physician visits because of respiratory illness among pregnant women
    Linda Dodds
    Canadian Centre for Vaccinology, Halifax, NS
    CMAJ 176:463-8. 2007
    ..We evaluated the impact of exposure during nonpandemic influenza seasons on the rates of hospital admissions and physician visits because of respiratory illness among pregnant women...
  57. ncbi Two-dose versus monthly intermittent preventive treatment of malaria with sulfadoxine-pyrimethamine in HIV-seropositive pregnant Zambian women
    Davidson H Hamer
    Center for International Health and Development, Boston University School of Public Health, Boston, MA 02118, USA
    J Infect Dis 196:1585-94. 2007
    ..However, the optimal dosing regimen in settings in which human immunodeficiency virus (HIV) is highly prevalent among pregnant women remains controversial...
  58. ncbi Maternal influenza infection is likely to alter fetal brain development indirectly: the virus is not detected in the fetus
    Limin Shi
    Biology Division, California Institute of Technology, Pasadena, CA 91125, USA
    Int J Dev Neurosci 23:299-305. 2005
    ..Thus, the effects of maternal infection on fetal brain development are likely to be indirect, probably involving the maternal inflammatory response...
  59. ncbi Prevalence of resistance to nevirapine in mothers and children after single-dose exposure to prevent vertical transmission of HIV-1: a meta-analysis
    Elise Arrive
    Unité INSERM 593, Bordeaux, France
    Int J Epidemiol 36:1009-21. 2007
    ..This systematic review and meta-analysis of summarized data aimed to estimate the proportion of mothers and children with NVP resistance mutations detected in plasma samples 4-8 weeks postpartum after single-dose NVP use for PMTCT...
  60. ncbi Probable mother to infant transmission of Pneumocystis jiroveci from an HIV-infected woman to her HIV-uninfected infant
    Lisa M McNally
    AIDS 19:1548-9. 2005
  61. ncbi Periodontal disease and upper genital tract inflammation in early spontaneous preterm birth
    Alice R Goepfert
    The Center for Research in Women s Health and the Department of Obstetrics and Gynecology, The University of Alabama at Birmingham, 619 19th Street, Birmingham, AL 35249 7333, USA
    Obstet Gynecol 104:777-83. 2004
    ..To estimate the relationship between maternal periodontal disease and both early spontaneous preterm birth and selected markers of upper genital tract inflammation...
  62. pmc Impact of round-the-clock, rapid oral fluid HIV testing of women in labor in rural India
    Nitika Pant Pai
    Division of Infectious Diseases and Immunodeficiency Service, Montreal Chest Institute, McGill University Health Center, Montreal, Canada
    PLoS Med 5:e92. 2008
    ..In this context, we investigated the impact of introducing round-the-clock, rapid, point-of-care HIV testing and counseling in a busy labor ward at a tertiary care hospital in rural India...
  63. ncbi Symptomatic congenital cytomegalovirus infection in infants born to mothers with preexisting immunity to cytomegalovirus
    S B Boppana
    Department of Pediatrics, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Pediatrics 104:55-60. 1999
    ..To determine the frequency of symptomatic congenital cytomegalovirus (CMV) infection in the offspring of women with a recurrent maternal CMV infection and to characterize the demographic and newborn findings...
  64. ncbi Maternal mortality associated with tuberculosis-HIV-1 co-infection in Durban, South Africa
    M Khan
    Medical Research Council, South Africa
    AIDS 15:1857-63. 2001
    ..Any attempt to improve maternal health must also include careful screening and investigation for tuberculosis in high-risk pregnant women...
  65. ncbi Epidemiology of invasive group B streptococcal disease in the United States, 1999-2005
    Christina R Phares
    Epidemic Intelligence Service Program, Office of Workforce and Career Development, Division of Bacterial Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    JAMA 299:2056-65. 2008
    ..Guidelines for prevention of perinatal disease through intrapartum chemoprophylaxis were revised in 2002. Candidate vaccines are under development...
  66. ncbi Prevention of mother-to-child transmission and voluntary counseling and testing programme data: what is their utility for HIV surveillance?
    Wolfgang Hladik
    Global AIDS Program, Centers for Disease Control and Prevention, Atlanta, GA, USA
    AIDS 19:S19-24. 2005
    ....
  67. ncbi Extracorporeal Membrane Oxygenation for 2009 Influenza A(H1N1) Acute Respiratory Distress Syndrome
    Andrew Davies
    FRACP, FJFICM, Intensive Care Unit, Alfred Hospital, Commercial Road, Melbourne, Victoria 3004, Australia
    JAMA 302:1888-95. 2009
    ..It caused an epidemic of critical illness and some patients developed severe acute respiratory distress syndrome (ARDS) and were treated with extracorporeal membrane oxygenation (ECMO)...
  68. ncbi Neonatal herpes simplex virus infection
    Richard Whitley
    University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    Curr Opin Infect Dis 17:243-6. 2004
    ..This review considers recent advances that impact on disease management...
  69. ncbi Maternal and fetal outcomes in pregnant women with acute hepatitis E virus infection
    Sharda Patra
    G B Pant Hospital and Lady Hardinge Medical College, New Delhi, India
    Ann Intern Med 147:28-33. 2007
    ..Hepatitis E virus (HEV) infection is known to cause severe liver disease in pregnant women. It is unclear whether obstetric and fetal outcomes are worse in pregnant women with HEV infection than in women with other forms of viral hepatitis...
  70. ncbi Contraceptive use, protected sexual intercourse and incidence of pregnancies among African HIV-infected women. DITRAME ANRS 049 Project, Abidjan 1995-2000
    Annabel Desgrées-du-Lou
    Institut de Recherche pour le Développement IRD and Ecole Nationale de Statistiques et d Economie Appliquée, ENSEA, Abidjan, Cote d Ivoire, France
    Int J STD AIDS 13:462-8. 2002
    ..The most educated women who cannot easily adopt this strategy are particularly exposed to unwanted pregnancies...
  71. ncbi HIV testing among pregnant women in Brazil: rates and predictors
    Valdilea G Veloso
    Instituto de Pesquisa Clinica Evandro Chagas, Fundacao Oswaldo Cruz, Rio de Janeiro, Brasil
    Rev Saude Publica 42:859-67. 2008
    ..To assess rates of offering and uptake of HIV testing and their predictors among women who attended prenatal care...
  72. ncbi Sociodemographic factors associated with participation by HIV-1-positive pregnant women in an intervention to prevent mother-to-child transmission of HIV in Cote d'Ivoire
    T M Painter
    Centers for Disease Control and Prevention, National Center for HIV, STD and TB Prevention, Division of HIV AIDS Prevention, Atlanta, GA 30333, USA
    Int J STD AIDS 16:237-42. 2005
    ..Greater attention to mitigating the effects of broader structural factors on women's participation in interventions may increase the effectiveness of MTCT prevention in Africa...
  73. ncbi Forgotten but not gone: the continuing scourge of congenital syphilis
    Damian G Walker
    Health Policy Unit, London School of Hygiene and Tropical Medicine, London, UK
    Lancet Infect Dis 2:432-6. 2002
    ..A task-force approach to defining the most appropriate interventions together with support for some research should be a priority for support under the Global Health Fund...
  74. ncbi Antenatal syphilis screening in sub-Saharan Africa: lessons learned from Tanzania
    Deborah Watson-Jones
    London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 10:934-43. 2005
    ....
  75. ncbi Declines in low birth weight and preterm birth among infants who were born to HIV-infected women during an era of increased use of maternal antiretroviral drugs: Pediatric Spectrum of HIV Disease, 1989-2004
    Joann Schulte
    Division of HIV AIDS Prevention, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    Pediatrics 119:e900-6. 2007
    ..Our goal was to determine trends in low birth weight and preterm birth among US infants born to HIV-infected women...
  76. pmc Maternal and congenital syphilis programmes: case studies in Bolivia, Kenya and South Africa
    Bidia D Deperthes
    Technical Officer, Department of Reproductive Health and Research, World Health Organization, 1211 Geneva 27, Switzerland
    Bull World Health Organ 82:410-6. 2004
    ....
  77. pmc Is antenatal syphilis screening still cost effective in sub-Saharan Africa
    F Terris-Prestholt
    London School of Hygiene and Tropical Medicine, London, UK
    Sex Transm Infect 79:375-81. 2003
    ..To compare this intervention with other antenatal and child health interventions, specifically the prevention of mother to child transmission of HIV (PMTCT)...
  78. pmc Multidisciplinary prospective study of mother-to-child chikungunya virus infections on the island of La Réunion
    Patrick Gerardin
    Neonatal and Pediatric Intensive Care Unit, pôle Mère Enfant, Groupe Hospitalier Sud Reunion, Saint Pierre, La Reunion, France
    PLoS Med 5:e60. 2008
    ....
  79. ncbi Determinants of low birth weight among HIV-infected pregnant women in Tanzania
    M L Dreyfuss
    Departments of Nutrition, Biostatistics, and Epidemiology, Harvard School of Public Health, Boston, MA, USA
    Am J Clin Nutr 74:814-26. 2001
    ..Low birth weight (LBW) increases the risk of infant death, but little is known about its causes among HIV-infected populations in sub-Saharan Africa...
  80. ncbi Listeriosis during pregnancy: a case series and review of 222 cases
    Eleftherios Mylonakis
    Division of Infectious Diseases, Massachusetts General Hospital, Boston, MA 02114, USA
    Medicine (Baltimore) 81:260-9. 2002
  81. ncbi Pregnancy outcomes in HIV-infected and uninfected women in rural and urban South Africa
    Nigel C Rollins
    Department of Paediatrics and Child Health, Nelson R Mandela School of Medicine, University of KwaZulu Natal, Congella 4013, South Africa
    J Acquir Immune Defic Syndr 44:321-8. 2007
    ..To describe pregnancy outcomes among clade C HIV-infected and uninfected women in South Africa...
  82. ncbi Association of HIV and malaria with mother-to-child transmission, birth outcomes, and child mortality
    Heena Brahmbhatt
    Department of Population and Family Health Sciences, Johns Hopkins University, Bloomberg School of Public Health, Baltimore, MD 21205, USA
    J Acquir Immune Defic Syndr 47:472-6. 2008
    ..To assess the impact of HIV and malaria coinfection on mother-to-child HIV transmission (MTCT) and adverse birth outcomes...
  83. pmc Maternal syphilis: pathophysiology and treatment
    Stuart M Berman
    Division of STD Prevention, Centers for Disease Control and Prevention, Atlanta, GA, USA 30306, USA
    Bull World Health Organ 82:433-8. 2004
    ....
  84. ncbi Prevalence of colonisation with group B Streptococci in pregnant women of a multi-ethnic population in The Netherlands
    Arijaan W Valkenburg-van den Berg
    Department of Obstetrics and Gynaecology, Medisch Centrum Haaglanden MCH, Westeinde Hospital, PO Box 432, 2501 CK The Hague, The Netherlands
    Eur J Obstet Gynecol Reprod Biol 124:178-83. 2006
    ..We calculated predictive values of cultures in pregnancy for intrapartum GBS carriage...
  85. ncbi Use of antiretroviral therapy in pregnant HIV-infected women and the risk of premature delivery: a meta-analysis
    Athena P Kourtis
    Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    AIDS 21:607-15. 2007
    ..The use of antiretroviral agents in pregnant HIV-infected women has been reported to increase the risk of premature delivery in some studies. We performed a meta-analysis on relevant studies to address this question...
  86. ncbi Prevalence and clinical course of chronic hepatitis C virus (HCV) infection and rate of HCV vertical transmission in a cohort of 15,250 pregnant women
    D Conte
    Cattedra di Gastroenterologia, IRCCS Ospedale Maggiore, Milan, Italy
    Hepatology 31:751-5. 2000
    ....
  87. pmc Washing our hands of the congenital cytomegalovirus disease epidemic
    Michael J Cannon
    National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA
    BMC Public Health 5:70. 2005
    ..More children are affected by serious CMV-related disabilities than by several better-known childhood maladies, including Down syndrome, fetal alcohol syndrome, and spina bifida...
  88. pmc Insensitivity of paediatric HIV-1 subtype C viruses to broadly neutralising monoclonal antibodies raised against subtype B
    Elin Solomonovna Gray
    AIDS Virus Research Unit, National Institute for Communicable Diseases, Johannesburg, South Africa
    PLoS Med 3:e255. 2006
    ..To assess the suitability of such an approach, we determined the sensitivity of paediatric HIV-1 subtype C viruses to the broadly neutralising MAbs IgG1b12, 2G12, 2F5, and 4E10...
  89. ncbi Single-dose perinatal nevirapine plus standard zidovudine to prevent mother-to-child transmission of HIV-1 in Thailand
    Marc Lallemant
    Epidémiologie Clinique, Santé Maternelle et Infantile et Sida, Institut de Recherche pour le Développement, Paris
    N Engl J Med 351:217-28. 2004
    ..We hypothesized that the administration, in addition to zidovudine, of a single dose of oral nevirapine to mothers during labor and to neonates would further reduce transmission of HIV...
  90. ncbi Efficacy of treatment for syphilis in pregnancy
    J M Alexander
    Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75235 9032, USA
    Obstet Gynecol 93:5-8. 1999
    ..To evaluate prospectively the Centers for Disease Control and Prevention (CDC) recommended regimens for the treatment of antepartum syphilis and prevention of congenital syphilis...
  91. ncbi Quantitative analysis of HBV DNA level and HBeAg titer in hepatitis B surface antigen positive mothers and their babies: HBeAg passage through the placenta and the rate of decay in babies
    Zhanhui Wang
    Department of Infectious Disease, Nanfang Hospital, The First Medical College of PLA, Guangzhou 510 515, China
    J Med Virol 71:360-6. 2003
    ..HBV DNA levels in hepatitis B carrier mothers are associated with the failure of HBIG and vaccine immunization, and the additional influence of transmitted HBeAg cannot be excluded...
  92. pmc Role of maternal autologous neutralizing antibody in selective perinatal transmission of human immunodeficiency virus type 1 escape variants
    Ruth Dickover
    Department of Pediatrics, David Geffen School of Medicine at UCLA, University of California Los Angeles, 10833 LeConte Ave, Los Angeles, CA 90095, USA
    J Virol 80:6525-33. 2006
    ..These data indicate that maternal autologous neutralizing antibody can exert powerful protective and selective effects in perinatal HIV-1 transmission and therefore has important implications for vaccine development...
  93. ncbi Prevention and treatment of influenza in high-risk groups: children, pregnant women, immunocompromised hosts, and nursing home residents
    Richard J Whitley
    University of Alabama at Birmingham, Birmingham, AL, 35233 1711, USA
    J Infect Dis 194:S133-8. 2006
    ..The development of additional antiviral drugs is an important recommendation for the future, so that antiviral resistance can be circumvented. Similarly, availability of drugs for children <1 year of age is mandatory...
  94. ncbi Managing Q fever during pregnancy: the benefits of long-term cotrimoxazole therapy
    Xavier Carcopino
    Service de Gynecologie Obstetrique, Hopital Nord, Chemin des Bourrely, France
    Clin Infect Dis 45:548-55. 2007
    ..During pregnancy, it may result in obstetric complications, such as spontaneous abortion, intrauterine growth retardation, intrauterine fetal death, and premature delivery. Pregnant women are exposed to the risk of chronic Q fever...
  95. ncbi Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda: 18-month follow-up of the HIVNET 012 randomised trial
    J Brooks Jackson
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    Lancet 362:859-68. 2003
    ..Safety and efficacy data are now presented for all babies followed up to 18 months of age...
  96. pmc Women in couples antenatal HIV counseling and testing are not more likely to report adverse social events
    Katherine Semrau
    Center for International Health and Development at the Boston University School of Public Health, Boston, Massachusetts 02118, USA
    AIDS 19:603-9. 2005
    ..Couple counseling has been promoted as a strategy to improve uptake of interventions to prevent mother-to-child HIV transmission (pMTCT) and to minimize adverse social outcomes associated with disclosure of HIV status...
  97. ncbi Routine intrapartum HIV counseling and testing for prevention of mother-to-child transmission of HIV in a rural Ugandan hospital
    Jaco Homsy
    Centers for Disease Control and Prevention CDC Uganda, Global AIDS Program, National Center for HIV, STD, and TB Prevention, CDC, and Uganda Virus Research Institute, Entebbe, Uganda
    J Acquir Immune Defic Syndr 42:149-54. 2006
    ..Routine HIV counseling and testing (HCT) during labor has been proposed as a way to increase PMTCT uptake, but little data exist on the impact of such intervention in a programmatic context in Africa...
  98. pmc A sonographic short cervix as the only clinical manifestation of intra-amniotic infection
    Sonia Hassan
    Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Wayne State University, Hutzel Women s Hospital, 3990 John R, 7 Brush North, MFM Mail Drawer 163, Detroit, MI 48201, USA
    J Perinat Med 34:13-9. 2006
    ..This study was conducted to determine the rate of MIAC and intra-amniotic inflammation in patients with a cervical length < 25 mm in the mid-trimester...
  99. pmc Measuring trends in prevalence and incidence of HIV infection in countries with generalised epidemics
    P D Ghys
    Joint United Nations Programme on AIDS UNAIDS, Avenue Appia 20, Geneva CH 1211, Switzerland
    Sex Transm Infect 82:i52-6. 2006
    ..Review of recent data and practice to derive guidance on questions relating to the measurement and analysis of trends in HIV prevalence and incidence...
  100. ncbi Maternal antiretroviral drugs during pregnancy and infant low birth weight and preterm birth
    Edgardo G Szyld
    Hosp Diego Paroissien, Brazil
    AIDS 20:2345-53. 2006
    ..The a priori hypothesis was that protease inhibitor (PI)-containing regimens are associated with an increased risk of LBW and preterm birth...
  101. ncbi Consequences of maternal anaemia on outcome of pregnancy in a malaria endemic area in Papua New Guinea
    B J Brabin
    Institute of Medical Research, Madang, Papua New Guinea
    Ann Trop Med Parasitol 84:11-24. 1990
    ..The extent to which malaria control, using drug treatment and chemoprophylaxis, can reduce the risk of low birthweight will vary in relation to the prevalence and causes of anaemia in women...

Research Grants68

  1. NUTRITION, IMMUNOLOGY, AND EPIDEMIOLOGY OF TB
    Wafaie Fawzi; Fiscal Year: 2004
    ..abstract_text> ..
  2. Partnership on Nutrition and HIV/AIDS Research in Tanza*
    Wafaie Fawzi; Fiscal Year: 2006
    ..The program will be carried out as a collaborative effort between Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania and the Harvard School of Public Health, Boston, MA. ..
  3. Genital Ulcer Disease and HIV Transmission
    Jeanne Sheffield; Fiscal Year: 2005
    ..The pursuit of these aims will further elucidate the cellular and molecular bases of the interrelationship between GUD and HIV-1 transmission, particularly in women. ..
  4. HIV PREVENTION TRIALS UNIT
    Wafaie Fawzi; Fiscal Year: 2004
    ..S., the commitment of the authorities in Tanzania to HIV research, and the political stability in Tanzania, would make this collaboration a valuable addition to the HPTN. ..
  5. Trial of Vitamins among Children of HIV-infected Mothers
    Wafaie Fawzi; Fiscal Year: 2007
    ..The study will be carried out as a collaborative effort between the Harvard School of Public Health and Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ..
  6. A TRAIL OF MICRONUTRIENTS AND ADVERSE PREGNACY OUTCOMES
    Wafaie Fawzi; Fiscal Year: 2003
    ..To examine potential mechanisms of action of the supplements or dietary patterns and intake of individual nutrients, they will assess the following secondary outcomes among women: hemoglobin levels, T cell counts, and placental weight. ..
  7. Trial of Vitamins in HIV Progression and Transmission
    Wafaie Fawzi; Fiscal Year: 2009
    ..The study is a collaborative effort between Harvard School of Public Health and Muhimbili University College of Health Sciences, Dar-es-Salaam, Tanzania. ..
  8. Serologic Studies of Prenatal Factors in Schizophrenia
    Alan Brown; Fiscal Year: 2002
    ..For this purpose, we shall quantify levels of these cytokines in 100 SSD cases and their respective matched controls, and compare these levels between the groups. ..
  9. Prenatal Factors and Risk of Bipolar Disorder
    ALAN STEWART BROWN; Fiscal Year: 2010
    ....
  10. Novel Strategy for Animal Model Testing of HCMV Vaccines
    Mark Schleiss; Fiscal Year: 2007
    ..These studies will represent the first efficacy test of a human CMV subunit vaccine in a small animal model of congenital CMV infection. [unreadable] [unreadable]..
  11. Protective cellular immune responses in HIV-1 discordant couples
    Carey Farquhar; Fiscal Year: 2010
    ....
  12. Protective Immune Responses in HIV-1 Exposed Infants
    Carey Farquhar; Fiscal Year: 2006
    ..Kreiss and John, will prepare her for the complex data analysis required by this study and contribute substantially to the development of her career as an independent clinical investigator. ..
  13. Safety Pharmacokinetics & Efficacy of Artemether & Lumefantrine in Pregnant Women
    Mark Mirochnick; Fiscal Year: 2008
    ..The data from this planned study will provide the information needed to ensure that pregnant women receive the appropriate doses of these anti-malaria drugs. [unreadable] [unreadable] [unreadable]..
  14. VACCINES FOR PREVENTION OF EXPERIMENTAL CONGENITAL CMV
    Mark Schleiss; Fiscal Year: 2009
    ..We anticipate that these subunit vaccine studies in this small animal model will clarify which strategies may be of value for vaccination against congenital HCMV infection. ..
  15. Pathogenesis of Essential Tremor: Cerebellar Metabolism
    Elan Louis; Fiscal Year: 2008
    ..abstract_text> ..
  16. Clinical Relevance of Transient Nevirapine Resistance
    Louise Kuhn; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  17. EFFECT OF CHRONIC INFECTION ON PLACENTAL DEVELOPMENT
    Kim Boggess; Fiscal Year: 2005
    ..Understanding of these mechanisms may assist in the development of interventions to protect the fetus and placenta from damage as a result of chronic maternal infection with oral pathogens. ..
  18. Mechanisms of myometrial healing and regeneration
    Catalin Buhimschi; Fiscal Year: 2006
    ....
  19. DEVELOPMENTAL INSULT AND BRAIN ANOMALY IN SCHIZOPHRENIA
    Alan Brown; Fiscal Year: 2004
    ....
  20. HIV Protective Immunity and Perinatal Exposure
    Louise Kuhn; Fiscal Year: 2006
    ..abstract_text> ..
  21. Antiretroviral Pharmacology/Lactating Mother/Infants
    Mark Mirochnick; Fiscal Year: 2006
    ..This information is needed for the safe and effective use of antiretrovirals in nursing women, and will pioneer a novel approach to the study of breast milk drug transfer. ..
  22. Transgenic Plant-Derived CMV Glycoprotein B Vaccine
    Mark Schleiss; Fiscal Year: 2007
    ..These studies will advance the fields of plant and CMV vaccines. [unreadable] [unreadable] [unreadable]..
  23. Understanding Barriers to Oral Health Care In Pregnancy: The First Step to Improv
    Kim Boggess; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  24. Prenatal factors and risk of autism in a Finnish national birth cohort
    ALAN STEWART BROWN; Fiscal Year: 2010
    ....
  25. CCR5 and CXCR4 Binding Chemokines and Oral HIV Infection
    Grace John Stewart; Fiscal Year: 2005
    ..abstract_text> ..
  26. Mechanisms for Racial Disparity in Preterm Birth
    Jane Hitti; Fiscal Year: 2006
    ....
  27. HIV-1 Specific Cytotoxic T Lymphocytes in Breastmilk
    Grace John Stewart; Fiscal Year: 2003
    ..The resulting findings will be relevant to development of vaccines for prevention of mother-to-child transmission of HIV-1. ..
  28. VIOLENCE AND SPONTANEOUS ABORTION IN INNER CITY WOMEN
    Deborah Nelson; Fiscal Year: 2002
    ....
  29. Developmental Disabilities in a Time of AIDS
    ADHIKARI MIRIAM; Fiscal Year: 2004
    ..abstract_text> ..
  30. Maternal Viral Infection and Fetal Brain Development
    Paul Patterson; Fiscal Year: 2008
    ..We will also use cytokine injections of non-infected mothers to help identify cytokines that may mediate the effects of maternal viral infection. ..
  31. Prevention of Cytomegalovirus Infection
    Stuart Adler; Fiscal Year: 2007
    ..The results of this study will establish if prevention of CMV infections is possible. [unreadable] [unreadable]..
  32. Early Diagnosis of Neonatal Candidiasis
    Daniel Benjamin; Fiscal Year: 2008
    ..abstract_text> ..
  33. Vertical transmission of Listeria monocytogenes
    Anna Bakardjiev; Fiscal Year: 2007
    ..The proposed research will provide important training which will prove crucial for the applicant when she becomes an independent physician scientist, her long-term goal. ..
  34. Maternal and Infant Health and HAART Outcomes in the Mashi PMTCT Study, Botswana
    Shahin Lockman; Fiscal Year: 2010
    ..placebo exposure;and pediatric neurodevelopmental and growth outcomes, by infant feeding modality and antiretroviral exposure history. ..
  35. Clinical Predictors of Antiretroviral Failure
    Daniel Benjamin; Fiscal Year: 2003
    ..abstract_text> ..
  36. Vitamins, Breast Milk HIV Shedding and Child Health
    Eduardo Villamor; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  37. Placental Immunopathology in the FIV-infected Cat Model
    KAREN COATS; Fiscal Year: 2006
    ..The production of immunomodulators will be examined in infected and uninfected pregnant cats. We hope to identify immune parameters promoting in utero viral transmission and fetal damage. [unreadable] [unreadable]..
  38. BEHAVIORAL INTERVENTION FOR CONGENITAL CMV DISEASE
    Stuart Adler; Fiscal Year: 2001
    ..The results of this trial will determine the effectiveness of behavioral intervention and the motivation necessary to adhere to recommendations and prevent child-to-mother transmission of CMV. ..
  39. The Role of NFkB in Huntington's Disease
    Paul Patterson; Fiscal Year: 2005
    ..These reagents will be injected into the brains of HD mice in tests of their efficacy in inhibiting mutant Htt toxicity and aggregation. They will also be tested on brain slices from HD mice, in the presence and absence of NMDA. ..
  40. HCV Treatment Cost-Effectiveness in 3 IDU Populations
    BRUCE SCHACKMAN; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  41. Mobilizing Adult Neural Stem Cells and Disease Models
    Paul H Patterson; Fiscal Year: 2010
    ..abstract_text> ..
  42. Burden of Malaria in Pregnancy in India
    Davidson Hamer; Fiscal Year: 2007
    ..The information generated by the study will also be instrumental in the development of new programs for preventing and mitigating the impact of MIP in India. [unreadable] [unreadable] [unreadable]..
  43. HIV PREVENTION TRIALS UNIT - MALAWI
    Taha Taha; Fiscal Year: 2006
    ..We intend to continue these studies and to expand to additional sites. ..
  44. 10th International CMV Workshop
    Stuart Adler; Fiscal Year: 2005
    ..The purpose is to keep everybody up to date and current about what's going on in all areas and stimulate new research projects and collaborations. We anticipate between 300 and 500 attendees. ..
  45. Peer Intervention as Pedagogic Paradigm in Kinshasa SPH
    Frieda Behets; Fiscal Year: 2006
    ..Main outcome measures will be self reported sexual risk behaviors and STI/HIV incidence. The work will inform HIV prevention policy and strengthen research and training at KSPH ..
  46. RESPIRATORY DISEASES/BSI STUDY
    Shahin Lockman; Fiscal Year: 2004
    ....
  47. COLUMBIA-ADARC-CORNELL AIDS CLINICAL TRIALS UNIT
    Scott Hammer; Fiscal Year: 2006
    ..Thus, the Columbia-ADARC ACTU will be an active participant in the Group's mission to improve the health of HIV infected individuals and set standards for treatment of HIV disease. ..
  48. Drug Resistance in Non-Subtype B HIV-1
    Susan Eshleman; Fiscal Year: 2005
    ..abstract_text> ..
  49. EPIDEMIOLOGY OF CMV
    Stuart Adler; Fiscal Year: 2007
    ..The results of this study will establish if immunization of mothers against CMV infection is possible. ..
  50. Neighborhood, Race and Alcohol Use /Abuse Trajectories
    Stephen Buka; Fiscal Year: 2004
    ..In addition, this study will also support the development of advanced statistical techniques needed to simultaneously estimate school and neighborhood contributions to race/ethnic disparities in alcohol use. ..
  51. ROLE OF CMV ENVELOPE GLYCOPROTEINS IN POLARIZED CELLS
    Lenore Pereira; Fiscal Year: 2003
    ....
  52. Metabolic Consequences of Thymidine Sparing Regimens
    Grace A McComsey; Fiscal Year: 2010
    ..at the top of each printed page and each continuation page. RESEARCH GRANT TABLE OF CONTENTS Page Numbers Face Page 1 Description, ..
  53. AIDS CLINICAL TRIALS
    Lisa Frenkel; Fiscal Year: 2002
    ..The PACTG site reports and regulatory evaluations of the UW PACTU which have generally been excellent are discussed. This proposal requests funds for the continuation of the successful UW PACTU. ..
  54. Mechanisms of Vascular Injury in the preterm lung
    Suhas Kallapur; Fiscal Year: 2006
    ..The experimental design in this proposal incorporates challenging but, particularly in this environment achievable goals that will provide important knowledge in the pathogenesis of bronchopulmonary dysplasia. ..
  55. Viral and Placental Determinants of HIV-1 Subtype C Mother-to-Child Transmission
    Jesse Kwiek; Fiscal Year: 2008
    ..The results of this project will provide a comprehensive description of the HIV-1 C envelope genes and the placental environment conducive to HIV-1 subtype C MTCT. ..
  56. Short Tandem Repeat Polymorphisms in Cytomegalovirus
    James Bale; Fiscal Year: 2003
    ..Characterizing HCM' strains by STR analysis will facilitate future studies of HCMV evolution and will provide a novel means t to fingerprint HCMV strains. ..
  57. Vulvar Disease and Bladder and Bowel Symptoms
    Colleen Kennedy; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  58. Transcripitonal and Genetic Profiles in HNSCCs
    Elaine Smith; Fiscal Year: 2008
    ..abstract_text> ..
  59. Risk and Resilience in Youth with HIV+ Mothers
    Claude Mellins; Fiscal Year: 2003
    ..At the end of Phase 2, we aim to have a feasible, culturally sensitive, effective prevention intervention that can be tested in a larger clinical trial with early adolescents affected by maternal HIV disease. ..
  60. Topical virucides to prevent oral transmission
    Koen van Rompay; Fiscal Year: 2004
    ..If topical tenofovir administration were effective, then this simple strategy would be highly affordable for developing countries. ..
  61. Intrauterine Inflammation & Adverse Neurological Outcome
    Michal A Elovitz; Fiscal Year: 2010
    ..abstract_text> ..
  62. Microcredit and Health Services Experiment in Bangladesh
    Stan Becker; Fiscal Year: 2010
    ....
  63. HIV counseling & testing among pregnant women, Tanzania
    Amy Medley; Fiscal Year: 2007
    ..Information from this study will help elucidate important barriers to the acceptance of VCT and allow the design of appropriate interventions. ..
  64. Dietary Glycemic Load, Obesity, and Birth Defect Risks
    Martha Werler; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  65. Fas/FasL System In Normal Mammary Gland Development
    Gil Mor; Fiscal Year: 2003
    ..With an improved foundation of the normal mammary physiology, we can advance the understanding of breast cancer, allowing the development of effective strategies for its treatment and prevention. ..
  66. DETECTING NEONATAL SEPSIS USING MOLECULAR TECHNIQUES
    JEANNE JORDAN; Fiscal Year: 2003
    ....
  67. Fas-Mediated Neutrophil Function in Neonates
    JOYCE KOENIG; Fiscal Year: 2003
    ..The studies outlined in this proposal will further our understanding of neutrophil biology in the developing human, and are critical to the design of future mechanistic studies. ..