tuberculoma

Summary

Summary: A tumor-like mass resulting from the enlargement of a tuberculous lesion.

Top Publications

  1. ncbi Tuberculoma of the brain: a series of 16 cases treated with anti-tuberculosis drugs
    M N A Idris
    Faculty of Medicine, University of Khartoum, Khartoum, Sudan
    Int J Tuberc Lung Dis 11:91-5. 2007
  2. ncbi Nonoperative management of an intramedullary tuberculoma
    Ish Kumar Dhammi
    Department of Orthopaedics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India
    Trop Doct 32:44-5. 2002
  3. ncbi Immunology of tuberculosis
    J L Flynn
    Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Annu Rev Immunol 19:93-129. 2001
  4. ncbi Intramedullary tuberculoma of the spinal cord: a series of 10 cases
    M C Sharma
    Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, 110 029, New Delhi, India
    Clin Neurol Neurosurg 104:279-84. 2002
  5. ncbi Evaluation of therapeutic response of tuberculoma using F-18 FDG positron emission tomography
    I Nae Park
    Division of Pulmonology and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Songpa Gu, Seoul, Korea
    Clin Nucl Med 33:1-3. 2008
  6. pmc Imaging diagnosis of spinal intramedullary tuberculoma: case reports and literature review
    Ming Lu
    Department of Radiology, Southwest Hospital, Chongquing, China
    J Spinal Cord Med 33:159-62. 2010
  7. ncbi Spinal intramedullary tuberculoma and abscess: a rare cause of paraparesis
    B Indira Devi
    Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Neurol India 50:494-6. 2002
  8. ncbi Multimodality FDG PET/CT appearance of pulmonary tuberculoma mimicking lung cancer and pathologic correlation in a tuberculosis-endemic country
    Zhi Zheng
    Department of Cardiothoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China
    South Med J 104:440-5. 2011
  9. pmc Massive primary hepatic tuberculoma mimicking hepatocellular carcinoma in an immunocompetent host
    Matthew J Brookes
    Gastroenterology Unit, City Hospital, Birmingham, United Kingdom
    MedGenMed 8:11. 2006
  10. pmc Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
    Hannah E Volkman
    Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, USA
    PLoS Biol 2:e367. 2004

Research Grants

Detail Information

Publications208 found, 100 shown here

  1. ncbi Tuberculoma of the brain: a series of 16 cases treated with anti-tuberculosis drugs
    M N A Idris
    Faculty of Medicine, University of Khartoum, Khartoum, Sudan
    Int J Tuberc Lung Dis 11:91-5. 2007
    To describe the clinical presentation, radiological findings and outcome of treatment with antituberculosis drugs in 16 cases of intracranial tuberculoma.
  2. ncbi Nonoperative management of an intramedullary tuberculoma
    Ish Kumar Dhammi
    Department of Orthopaedics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Delhi, India
    Trop Doct 32:44-5. 2002
  3. ncbi Immunology of tuberculosis
    J L Flynn
    Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15261, USA
    Annu Rev Immunol 19:93-129. 2001
    ..The pace of this research must be maintained if we are to realize an effective vaccine in the next decades...
  4. ncbi Intramedullary tuberculoma of the spinal cord: a series of 10 cases
    M C Sharma
    Department of Pathology, All India Institute of Medical Sciences, Ansari Nagar, 110 029, New Delhi, India
    Clin Neurol Neurosurg 104:279-84. 2002
    ..We report a series of ten cases of intramedullary tuberculomas, which, to the best of our knowledge, is the largest series of biopsy proven intramedullary tuberculomas in English literature...
  5. ncbi Evaluation of therapeutic response of tuberculoma using F-18 FDG positron emission tomography
    I Nae Park
    Division of Pulmonology and Critical Care Medicine, University of Ulsan College of Medicine, Asan Medical Center, Songpa Gu, Seoul, Korea
    Clin Nucl Med 33:1-3. 2008
    Monitoring the response to antituberculosis (anti-TB) treatment can be difficult in patients with tuberculoma. We have retrospectively assessed the ability of F-18 fluoro-2-deoxy-D-glucose positron emission tomography (FDG-PET) to ..
  6. pmc Imaging diagnosis of spinal intramedullary tuberculoma: case reports and literature review
    Ming Lu
    Department of Radiology, Southwest Hospital, Chongquing, China
    J Spinal Cord Med 33:159-62. 2010
    Spinal intramedullary tuberculoma is rare, accounting for 2/100,000 of cases of tuberculosis and only 2% of all cases of tuberculosis of the central nervous system...
  7. ncbi Spinal intramedullary tuberculoma and abscess: a rare cause of paraparesis
    B Indira Devi
    Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore 560 029, India
    Neurol India 50:494-6. 2002
    ..In other cases following surgical excision, the patients improved significantly. The management of these rare lesions is discussed and the literature reviewed...
  8. ncbi Multimodality FDG PET/CT appearance of pulmonary tuberculoma mimicking lung cancer and pathologic correlation in a tuberculosis-endemic country
    Zhi Zheng
    Department of Cardiothoracic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, PR China
    South Med J 104:440-5. 2011
    Differentiation between pulmonary tuberculoma and malignancy by preoperative diagnostic imaging sometimes proves difficult...
  9. pmc Massive primary hepatic tuberculoma mimicking hepatocellular carcinoma in an immunocompetent host
    Matthew J Brookes
    Gastroenterology Unit, City Hospital, Birmingham, United Kingdom
    MedGenMed 8:11. 2006
    b>Tuberculoma of the liver is rare in an immunocompetent individual. We report a 26-year-old man with upper abdominal pain, abnormal liver function, and raised inflammatory markers...
  10. pmc Tuberculous granuloma formation is enhanced by a mycobacterium virulence determinant
    Hannah E Volkman
    Molecular and Cellular Biology Graduate Program, University of Washington, Seattle, Washington, USA
    PLoS Biol 2:e367. 2004
    ..This Mycobacterium-induced macrophage aggregation in turn is tightly linked to intercellular bacterial dissemination and increased bacterial numbers. Thus, mycobacteria co-opt host granulomas for their virulence...
  11. ncbi An intradural extramedullary tuberculoma of the spinal cord in a non-HIV-infected patient: case report and review of the literature
    Lan Luo
    Department of Internal Medicine, Coastal AHEC, University of North Carolina School of Medicine, 2131 South 17th Street, Wilmington, NC 28409, USA
    Lung 184:187-93. 2006
    ..Our case is the only documented intradural extramedullary tuberculoma in a non-HIV-infected patient in North America...
  12. ncbi Intradural extramedullary tuberculoma of the spinal cord: a review of reported cases
    Bernardino Roca
    Infectious Disease Division, Department of Medicine, Hospital General of Castellon, Castellon, Spain
    J Infect 50:425-31. 2005
    Intradural extramedullary tuberculoma of the spinal cord (IETSC) is a rare modality of tuberculosis, with only a few cases described so far. Here we review 22 reports of the disease found in the literature of the last 25 years...
  13. ncbi MRI features of tuberculoma of the right atrial myocardium
    Priya Jagia
    Department of Cardiovascular Radiology, All India Institute of Medical Sciences, New Delhi, India
    Pediatr Radiol 34:904-7. 2004
    ..We describe the MRI features in a 12-year-old boy with myocardial tuberculoma of the right atrium. He also had intracerebral tuberculoma. The diagnosis was later confirmed by biopsy.
  14. ncbi Intracardiac tuberculoma
    B C Chang
    Yonsei Cardiovascular Center, and Department of Pathology, Yonsei University College of Medicine, Seoul, Korea
    Ann Thorac Surg 67:226-8. 1999
    We examined a case of endocardial tuberculoma at the proximal superior vena cava and the right atrium in a 17-year-old male patient...
  15. ncbi Fever and night sweats in a 22-year-old man with a mediastinal mass involving the heart
    Micha Maeder
    Division of Pulmonary Medicine, Department of Medicine, Hospital of St Gallen, St Gallen, Switzerland
    Chest 124:2006-9. 2003
  16. ncbi Choroidal tuberculoma in pregnancy
    Jie Shen
    Department of Ophthalmology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China
    Retina 27:106-9. 2007
  17. doi Superior vena caval obstruction after complete resolution of cardiac tuberculoma
    G Singh Gulati
    Department of Cardiac Radiology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
    Clin Radiol 63:605-9. 2008
  18. ncbi Differential organization of the local immune response in patients with active cavitary tuberculosis or with nonprogressive tuberculoma
    Timo Ulrichs
    Department of Immunology, Max Planck Institute for Infection Biology, Institute for Infection Medicine, Charite University Medicine, Campus Benjamin Franklin, Berlin, Germany
    J Infect Dis 192:89-97. 2005
    ..Failure of this containment leads to reactivation of postprimary tuberculosis (TB). The regional immune processes that sustain the delicate balance with persistent M. tuberculosis, however, remain unclear...
  19. ncbi Tuberculoma of the heart
    Pradeep Vaideeswar
    Cardiovascular and Thoracic Division, Department of Pathology, Seth G S Medical College, Parel, Mumbai 400 012, India
    Cardiovasc Pathol 15:55-6. 2006
  20. ncbi Renal macronodular tuberculoma: CT and MR findings in an asymptomatic patient
    G Verswijvel
    Dep Of Radiology, Ziekenhuis Oost Limburg, Genk, Belgium
    JBR-BTR 85:203-5. 2002
    ..On MR imaging the lesion was hypointense on T1-weighted images, and T2-weighted images demonstrated a thick irregular hypointense peripheral wall and an intralesional fluid debris level. Gadolinium-chelates were not administered...
  21. ncbi DTI derived indices correlate with immunohistochemistry obtained matrix metalloproteinase (MMP-9) expression in cellular fraction of brain tuberculoma
    Rakesh K Gupta
    Department of Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    J Neurol Sci 275:78-85. 2008
    ..In addition, these indices may be of value in assessing the therapeutic response in patients with BT who are treated only with specific anti-tuberculous drugs...
  22. ncbi Orbital tuberculoma extending into the cranium
    Taru Dewan
    Department of Ophthalmology, Dr Ram Manohar Lohia Hospital, New Delhi, India
    Ophthalmologica 220:137-9. 2006
    Orbital tuberculoma is not uncommon in the developing countries, but intracranial extension of orbital tuberculoma is extremely rare...
  23. doi Images in cardiovascular medicine. Cardiac tuberculoma
    Mohamed Jeilan
    Department of Cardiology, Glenfield Hospital, Groby Rd, Leicester LE3 9QP, UK
    Circulation 117:984-6. 2008
  24. ncbi Intramedullary cervical tuberculoma
    J Lin
    Department of Neurosurgery, Southwest Hospital, Third Military Medical University, Gaotanyan, Shapingba District, Chongqing, The People s Republic of China
    Spinal Cord 44:809-12. 2006
    ..Case report...
  25. ncbi Immune reconstitution syndrome in a patient with AIDS with paradoxically deteriorating brain tuberculoma
    Chen Hsiang Lee
    Division of Infectious Diseases, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan, Republic of China
    AIDS Patient Care STDS 21:234-9. 2007
    ..of the concurrent pulmonary tuberculosis (TB), presumptive diagnosis of tuberculous meningitis and brain tuberculoma was made...
  26. pmc A rare site for tuberculosis
    Amitabh Monga
    Department of Internal Medicine, Sitaram Bhartia Institute of Science and Research, New Delhi, India
    CMAJ 167:1149-50. 2002
  27. ncbi Intramedullary spinal tuberculoma: report of three cases
    Hao Li
    Department of Neurosurgery, Huaxi Hospital of Sichuan University, Chengdu 610041, China
    Surg Neurol 65:185-8; discussion 188-9. 2006
    Intramedullary spinal tuberculoma is a rare form of central nervous system tuberculosis. This article describes the successful management of intramedullary spinal tuberculoma in 3 patients who received treatment between 2000 and 2003.
  28. pmc Neurological picture. Dorsal intramedullary tuberculoma
    Mohammad Tahir
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Neurol Neurosurg Psychiatry 78:1353. 2007
  29. ncbi Solitary choroidal tuberculoma in an immunocompetent patient
    Laurent J Levecq
    Ocular Oncology Unit, Cliniques Universitaires St Luc, 10 Avenue Hippocrate, 1200 Brussels, Belgium
    Arch Ophthalmol 123:864-6. 2005
  30. ncbi Tuberculoma of the cervical spinal canal mimicking en plaque meningioma
    Hasan Mirzai
    Department of Neurosurgery, Celal Bayar University School of Medicine, Manisa, Turkey
    J Spinal Disord Tech 18:197-9. 2005
    ..examination of the mass revealed granulomas with multinucleated and Langhans-type giant cells, typical of a tuberculoma. Intradural extramedullary tuberculomas should be considered in the differential diagnosis of en plaque ..
  31. ncbi Intradural, eextramedullary tuberculoma of the spinal cord as a complication of tuberculous meningitis
    P Skendros
    Dept of Internal Medicine, Hospital of Infectious Diseases, Grigoriou Lampraki 13 str, GR 54638 Thessaloniki, Greece
    Infection 31:115-7. 2003
    An unusual case of an intradural, extramedullary spinal cord tuberculoma, as a complication of tuberculous meningitis caused by a strain susceptible to major anti-TB drugs, is described in a previously healthy, HIV-negative, 27-year-old ..
  32. ncbi Pituitary tuberculoma--a case report
    D K Manghani
    Department of Neuropathology, MRC 15th Floor, Bombay Hospital, Mumbai-400 020, India
    Neurol India 49:299-301. 2001
    ..The lesion was approached trans-sphenoidally and pathological examination revealed a tuberculoma. Complete removal was achieved and the patient followed on anti-tuberculous therapy.
  33. ncbi Tuberculoma presenting as an intradural extramedullary lesion
    Rajinder Kumar
    Department of Neurosurgery, Neurosciences Centre, All India Institute of Medical Sciences, New Delhi, India
    Pediatr Neurosurg 43:541-3. 2007
  34. pmc Intracardiac left atrial tuberculoma in an eleven-month-old infant: case report
    M Cantinotti
    Department of Sciences for Woman and Child s Health, University of Florence, Anna Meyer Children s University Hospital, Florence, Italy
    BMC Infect Dis 11:359. 2011
    ..Involvement of other part of the heart is unusual and descriptions in the pediatric literature are confined to few case reports regarding mainly myocardial tuberculosis...
  35. ncbi Obstruction of the right ventricular outflow tract caused by a tuberculoma in a patient with ventricular septal defect and aneurysm of the membranous septum
    C L Santos
    Heart Institute of Pernambuco, Recife, Brazil
    Cardiol Young 9:509-11. 1999
    Reported here is an obstruction of the right ventricular outflow tract caused by a tuberculoma in a 15-year-old boy who presented with a ventricular septal defect...
  36. ncbi Intradural extramedullary tuberculoma of the thoracic spine: paradoxical response to antituberculous therapy
    Hirokatsu Takahashi
    Department of Neurology, Graduate School of Medicine, Chiba University, Chiba
    Intern Med 47:797-8. 2008
    Intradural extramedullary tuberculoma of the spinal cord (IETSC) is a rare complication of tuberculosis, which can occur as a paradoxical response to antituberculous therapy...
  37. ncbi Magnetic resonance spectroscopy in pituitary tuberculoma
    K S Saini
    Department of Medicine, Grant Medical College, Sir JJ Group of Hospitals, Byculla, Mumbai 400008, India
    Singapore Med J 48:783-6. 2007
    ..It demonstrated features characteristic of a tuberculoma. She showed marked clinical improvement after she was started on anti-tuberculous drugs...
  38. ncbi Diagnostic utility of polymerase chain reaction and immunohistochemical techniques for the laboratory diagnosis of intracranial tuberculoma
    M G Sumi
    Department of Pathology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala State, India
    Clin Neuropathol 20:176-80. 2001
    ..IHC) methods were undertaken in formalin-fixed paraffin sections of ten surgical specimens of intracranial tuberculoma. The control group included an equal number of intracranial fungal granuloma...
  39. ncbi Middle and posterior fossa aspergilloma
    Jacob P Alapatt
    Department of Neurosurgery, Medical College Hospital, Thrissur, Kerala 680001, India
    Surg Neurol 66:75-8; discussion 78-9. 2006
    ..Because of its rarity in immunocompetent patients and the difficulty in preoperative diagnosis, we have illustrated this case and its presentation and management...
  40. pmc A case of oculomotor nerve palsy and choroidal tuberculous granuloma associated with tuberculous meningoencephalitis
    Sunghyuk Moon
    Department of Ophthalmology, Yeungnam University College of Medicine, Daegu, Korea
    Korean J Ophthalmol 22:201-4. 2008
    ..isolated left oculomotor nerve palsy, which manifested as ptosis, and a fundus examination revealed choroidal tuberculoma. Other anti-tuberculous drugs (pyrazinamide, ethambutol) and a steroid (dexamethasone) were added...
  41. pmc Intramedullary tuberculoma mimicking primary CNS lymphoma
    A A Mohit
    Department of Neurological Surgery, University of Washington School of Medicine, Seattle, USA
    J Neurol Neurosurg Psychiatry 75:1636-8. 2004
    ..After failing to respond to radiotherapy, he underwent a spinal cord biopsy revealing intramedullary tuberculoma. This case illustrates the risk of misdiagnosis with this assay and the importance of histological confirmation ..
  42. ncbi Female genital tuberculosis: uncommon presentation of tuberculosis in the United States
    Ali Hassoun
    Alabama Infectious Disease Center, Huntsville, Ala 35801, USA
    Am J Med 118:1295-6. 2005
  43. ncbi [Pulmonary tuberculoma]
    Olivier Fain
    Service de Medecine Interne, Hopital Jean Verdier, 93143 Bondy
    Rev Prat 55:1751. 2005
  44. ncbi [Radiologic diagnosis of lung tuberculosis]
    E Eisenhuber
    Institut für Röntgendiagnostik, Otto Wagner Spital, Sanatoriumsstr 2, A 1140, Wien, Austria
    Radiologe 47:393-400. 2007
    ..Depending on the immune status of the patient, the morphologic spectrum of tuberculosis is quite variable. Early diagnosis of tuberculosis is essential to prevent further spread of the disease...
  45. ncbi Serial MRI to determine the effect of dexamethasone on the cerebral pathology of tuberculous meningitis: an observational study
    Guy E Thwaites
    Oxford University Clinical Research Unit, Hospital for Tropical Diseases, Ho Chi Minh City, Vietnam
    Lancet Neurol 6:230-6. 2007
    ..We aimed to determine the effect of dexamethasone on cerebral MRI changes and their association with intracerebral inflammatory responses and clinical outcome in adults treated for tuberculous meningitis...
  46. ncbi Perforated tuberculous appendicitis and peritoneal tuberculosis
    T Dogru
    Department of Internal Medicine, Gulhane Medical School, Ankara, Turkey
    East Mediterr Health J 14:742-4. 2008
  47. ncbi [Tuberculosis of the wrist. Symptoms and outcome in eleven cases]
    M Benchakroun
    Clinique Chirurgicale de Traumatologie Orthopédie, Hopital Avicenne, CHU Ibn Sina, Rabat, Maroc
    Rev Chir Orthop Reparatrice Appar Mot 90:337-45. 2004
    ..We present our experience with a rare localization of tuberculosis, the wrist, focusing on symptoms and outcome after treatment...
  48. ncbi Right atrial tuberculoma: computed tomography and magnetic resonance imaging
    Abdul M Alkhulaifi
    Cardiac Surgery Department, Hamad General Hospital, Doha, Qatar
    J Thorac Cardiovasc Surg 133:808. 2007
  49. ncbi Response of pulmonary tuberculomas to anti-tuberculous treatment
    H S Lee
    Division of Respiratory and Critical Care Medicine, Dept of Internal Medicine and Lung Institute of Medical Research Centre, Seoul National University College of Medicine, Seoul, Republic of Korea
    Eur Respir J 23:452-5. 2004
    ..The majority of pulmonary tuberculomas were decreased by anti-tuberculosis treatment during and even after treatment, although a transient enlargement during the early period of treatment was observed infrequently...
  50. ncbi Intramedullary tuberculoma of the conus
    Awadhesh Kumar Jaiswal
    Department of Neurosurgery, St Stephen s Hospital, Tees Hazari, New Delhi, India
    J Clin Neurosci 13:870-2. 2006
    We present a conus medullaris tuberculoma in a 12-year-old girl. She presented with low backache, weakness of both lower limbs and urinary disturbance. Magnetic resonance imaging revealed a D10-L1 intramedullary mass...
  51. ncbi En plaque intradural extramedullary spinal tuberculoma and concurrent intracranial tuberculomas: paradoxical response to antituberculous therapy. Case report
    Natarajan Muthukumar
    Department of Neurosurgery, Madurai Medical College, Madurai, India
    J Neurosurg Spine 6:169-73. 2007
    Spinal intradural extramedullary tuberculoma is a rare entity...
  52. ncbi Primary parotid tuberculosis: varied clinical presentations
    A Sethi
    Department of ENT and Head and Neck Surgery, Maulana Azad Medical College and associated L N Hospital, New Delhi, India
    Oral Dis 12:213-5. 2006
    ..The cases were diagnosed on the basis of histopathological evaluation and fine needle aspiration cytology. All the patients responded to four-drug antitubercular chemotherapy...
  53. ncbi Retrovesical tuberculosis
    M Raghavendran
    Department of Urology and Renal Transplantation, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    Urology 63:582-3. 2004
  54. ncbi Lung infection in radiology: a summary of frequently depicted signs
    I M Van Mieghem
    Department of Radiology, University Hospitals Gasthuisberg, Leuven, Belgium
    JBR-BTR 88:66-71. 2005
    ..However there are some radiological signs, which are very suggestive in predicting the causal organism or in predicting the way of spread of the infection...
  55. ncbi Hepatic tuberculomas. A case report
    Djordje Culafic
    Institute of Digestive Diseases, Mirjevski Venac br 49, Beograd 11160, Serbia and Montenegro
    Rom J Gastroenterol 14:71-4. 2005
    ..The liver is often involved secondarily by sytemic/extrahepatic vascular, metabolic, infectious, granulomatous, and malignant processes...
  56. ncbi Multiple splenic macronodular tuberculomas: MRI characteristics under treatment
    Anastasia Oikonomou
    Int J Tuberc Lung Dis 10:233-4. 2006
  57. ncbi Obstructive granulomatous bronchiolitis obliterans due to Mycobacterium tuberculosis
    R Agarwal
    Department of Pulmonary Medicine, Postgraduate Institute of Medical Education and Research, Chandigarh 160012, India
    Monaldi Arch Chest Dis 63:108-10. 2005
    ..The authors present a case of tubercular granulomatous bronchiolitis obliterans, confirmed on histopathology, who responded completely to anti-tubercular chemotherapy...
  58. ncbi Modern imaging of spinal tuberculosis
    Seth S Joseffer
    Department of Neurosurgery, New York University Medical Center, New York, New York, USA
    J Neurosurg Spine 2:145-50. 2005
    ....
  59. ncbi Brainstem tuberculoma presenting as eight-and-a-half syndrome
    Ronald van Toorn
    Department of Pediatrics and Child Health, Faculty of Health Sciences, Stellenbosch University and Tygerberg Children s Hospital, Tygerberg 7505, Western Cape, South Africa
    Eur J Paediatr Neurol 10:41-4. 2006
    We present a case of a young child who developed eight-and-a-half syndrome following a pontine tuberculoma, an unusual complication of central nervous system tuberculosis not previously described in an immunocompetent child...
  60. ncbi [Laryngeal sarcoidosis: review of a case]
    J Aguilar-García
    An Med Interna 23:145. 2006
  61. ncbi Clinical and radiological features of symptomatic central nervous system tuberculomas
    A Unal
    Neurology Department, Zonguldak Karaelmas University, Faculty of Medicine, Zonguldak, and 3rd Neurology Department, Bakirkoy Research and Training Hospital for Psychiatric and Neurological Diseases, Istanbul, Turkey
    Eur J Neurol 12:797-804. 2005
    ..Because of the possibility of late development of tuberculomas after initial successful treatment, all TBM patients need to be followed-up carefully for a long period...
  62. ncbi The impersonator
    Hartmut Lode
    Charite Universitatsmedizin Berlin, Berlin, Germany
    Am J Med 120:239-41. 2007
  63. ncbi Intra-medullary tuberculoma occurring during treatment of tuberculous meningitis
    V B Shaharao
    Indian J Pediatr 71:107-8. 2004
  64. ncbi [Histological and immunohistochemical structure of pulmonary tuberculotic granulomas in untreated cases and cases treated with antitubercular drugs]
    Jozsef Furak
    Szegedi Tudomanyegyetem, Szent Györgyi Albert Orvos és Gyógyszerésztudományi Centrum, Sebészeti Klinika
    Orv Hetil 144:1347-52. 2003
    ..The changes occurring in response to antituberculotic treatment and immune defence were studied in human tuberculotic granulomas...
  65. ncbi [Pseudotumor form of bronchial tuberculosis]
    M Rguibi
    Presse Med 32:501. 2003
  66. ncbi Sarcoid reaction in primary tumor of bronchogenic large cell carcinoma accompanied with massive necrosis
    K Kashiwabara
    Respiratory Department, Taragi Municipal Hospital, Kumamoto
    Intern Med 40:127-30. 2001
    ..She was given a diagnosis of pulmonary tuberculoma because percutaneous needle aspiration cytology revealed epithelioid cells with a background of necrosis...
  67. ncbi [A case of miliary tuberculosis complicated with SIADH, brain tuberculoma, and tuberculous meningitis]
    Makoto Takahara
    Department of Internal Medicine, National Nishi Kofu Hospital, 3368, Yamamiya, Kofu shi, Yamanashi, 400 0075, Japan
    Kekkaku 77:67-72. 2002
    ..LVFX, high concentration in CSF, was added. At present (2 yrs after beginning the therapy), lesions in the brain and spinal cord improved but remain with the sequelae...
  68. ncbi Tuberculous mediastinal mass presenting with stridor in a 3-month-old child
    Daniel A De Ugarte
    Division of Pediatric Surgery, UCLA Medical Center, Los Angeles, California, USA
    J Pediatr Surg 38:624-5. 2003
    ..Further investigations found a mediastinal mass compressing the carina and left mainstem bronchus. The mass was excised and found to be of tuberculous origin...
  69. ncbi Intramedullary tuberculoma of the conus medullaris: case report and review of the literature
    S Kemaloglu
    Department of Neurosurgery, School of Medicine, Dicle University, 21100 Diyarbakir, Turkey
    Spinal Cord 39:498-501. 2001
    ..To illustrate the dilemmas in the diagnosis and management of intramedullary tuberculomas of the spinal cord...
  70. ncbi [Orbital tuberculoma]
    C Stan
    Clinica Oftalmologica Cluj-Napoca
    Oftalmologia 52:35-7. 2001
    ..The histological examination of a piece of the tumor showed tuberculous characteristics. Patient received treatment with antituberculous drugs and steroids. The tumor decreased after two months of treatment...
  71. ncbi Complete resection is mandatory for tubercular cold abscess of the chest wall
    Young Tae Kim
    Department of Thoracic and Cardiovascular Surgery, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea
    Ann Thorac Surg 85:273-7. 2008
    ..Cold abscess of the chest wall is a rare disease and few literature reports detail any treatment experience with a limited patient number. Hence, an optimal treatment plan remains controversial...
  72. ncbi CT of tuberculosis and nontuberculous mycobacterial infections
    Jin Mo Goo
    Department of Radiology, Seoul National University College of Medicine, South Korea
    Radiol Clin North Am 40:73-87, viii. 2002
    ....
  73. ncbi An unusual case of craniovertebral junction tuberculosis in an infant
    Sudhir K Kapoor
    Lady Hardinge Medical College and Associated Hospitals, New Delhi, India
    Spine (Phila Pa 1976) 32:E678-81. 2007
    ..We present, to the best of our knowledge, the first reported case of craniovertebral junction tuberculosis with complete quadriplegia in an infant...
  74. ncbi [Intramedullary spinal tuberculoma: report of one case]
    C F Litre
    Service de Neurochirurgie, Hopital de la Timone, 264, Boulevard Saint Pierre, 13385 Marseille Cedex 05, France
    Neurochirurgie 54:545-7. 2008
    ..Intramedullary tuberculoma is an exceptional location...
  75. ncbi Tuberculoma of the conus medullaris: case report
    Kudret Tureyen
    Department of Neurosurgery, Konur Hospital, Bursa, Turkey
    Neurosurgery 50:651-2; discussion 652-3. 2002
    Intramedullary spinal tuberculoma is a rare form of central nervous system tuberculosis. This article describes an affected patient who presented with left leg paresis.
  76. ncbi Treatment of intraspinal tuberculoma
    Sudhir Kumar
    Department of Orthopaedics, University College of Medical Sciences and Guru Teg Bahadur Hospital, Shahdara, Delhi, India
    Clin Orthop Relat Res 460:62-6. 2007
    Neurological manifestations in spinal tuberculosis often occur secondary to vertebral involvement. However, tuberculoma of the spinal cord or extradural granuloma without radiological evidence of vertebral involvement may be responsible ..
  77. ncbi Cervical intramedullary tuberculoma: acute presentation and rapid response to medical therapy
    Deepak Bansal
    Department of Pediatrics, Advanced Pediatric Center, Post Graduate Institute of Medical Education and Research, Chandigarh, India
    J Trop Pediatr 48:55-7. 2002
    ..MRI of the spine revealed an intramedullary tuberculoma at the level of C5-7. Investigations further revealed evidence of tuberculosis in the brain and lungs as well...
  78. ncbi Simultaneous tuberculous meningoencephalitis in two siblings
    Sascha Meyer
    Department of Pediatrics and Paediatric Intensive Care, University Hospital of Saarland, Homburg, Germany
    Wien Med Wochenschr 157:37-42. 2007
    ..These case reports demonstrate an unusual simultaneous occurrence of TBM in a brother and sister. It draws attention to the importance of TBM as a differential diagnosis in children with suspected viral meningoencephalitis...
  79. ncbi [Tubercular granulomas of the liver in a Somalian patient notwithstanding a chronic hepatitis C]
    R W Vreede
    Afd. Medische Microbiologie, Reinier de Graaf Gasthuis, Reinier de Graafweg 3-11, 2625 AD Delft
    Ned Tijdschr Geneeskd 145:535-8. 2001
    ..No side effects of the tuberculostatic treatment were seen on the course of the hepatitis C...
  80. ncbi [Lytic lesion in the femoral condyle in a female patient with human immunodeficiency virus infection]
    Koldo Aguirrebengoa
    Unidad de Enfermedades Infecciosas, Hospital de Cruces, Vizcaya, Spain
    Enferm Infecc Microbiol Clin 20:37-8. 2002
  81. ncbi Tuberculous retropharyngeal abscess
    M Panduranga Kamath
    Department of Otolaryngology Head and Neck Surgery, Kasturba Medical College, Mangalore, Karnataka State, India
    Ear Nose Throat J 86:236-7. 2007
    ..We present the case of a patient who came to our clinic with collapse of the C5-C6 vertebrae and retropharyngeal abscess. We were able to avoid any complications by initiating early surgical drainage and antituberculous therapy...
  82. ncbi British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children
    Guy Thwaites
    Centre for Molecular Microbiology and Infection, Imperial College, Exhibition Road, South Kensington, London, UK
    J Infect 59:167-87. 2009
    ..We have presented guidance on tuberculous meningitis (TBM), intra-cerebral tuberculoma without meningitis, and tuberculosis affecting the spinal cord. Our key recommendations are as follows: 1...
  83. ncbi [Multi-slice helical CT perfusion imaging in evaluating intracranial neoplasms and tumor-like lesions]
    Qing Bo Zhang
    Department of Diagnostic Radiology, Huashan Hospital, Fudan University, Shanghai 200040, China
    Zhonghua Zhong Liu Za Zhi 29:131-5. 2007
    ..To investigate the clinical value of CT perfusion in diagnosing and assessing intracranial neoplasms and tumor-like lesions...
  84. ncbi Unusual benign focal liver lesions: findings on real-time contrast-enhanced sonography
    Hui Xiong Xu
    Department of Medical Ultrasonics, First Affiliated Hospital, Sun Yat Sen University, Guangzhou, China
    J Ultrasound Med 27:243-54. 2008
    ..This presentation aims to provide an overview of the manifestations of some unusual benign focal liver lesions (FLLs) on low-acoustic power contrast-enhanced sonography (CES) with a sulfur hexafluoride contrast agent...
  85. ncbi Identification of diffuse and focal brain lesions by clinical magnetic resonance spectroscopy
    Peter B Kingsley
    Department of Radiology, North Shore University Hospital, 300 Community Drive, Manhasset, NY 11030, USA
    NMR Biomed 19:435-62. 2006
    ..encephalitis (herpes simplex, Rasmussen's and subacute sclerosing panencephalitis), neurocysticercosis, tuberculoma, cysts (arachnoid, epidermoid and hydatid), acute disseminated encephalomyelitis (ADEM), adrenoleukodystrophy (..
  86. ncbi Assessment of antibody responses to antigens of Mycobacterium tuberculosis and Cysticercus cellulosae in cerebrospinal fluid of chronic meningitis patients for definitive diagnosis as TBM/NCC by passive hemagglutination and immunoblot assays
    Muralidhar K Katti
    Immunology Laboratory, Department of Microbiology, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvanathapuram 695 011, India
    FEMS Immunol Med Microbiol 33:57-61. 2002
    ..chronic infections of the central nervous system with the possible diagnosis of tuberculous meningitis (TBM), tuberculoma and neurocysticercosis (NCC) (n=88), and group II - controls which included (a) non-infectious non-neurological ..
  87. ncbi A visual and semi-quantitative assessment of (99m)Tc-EDDA/HYNIC-TOC scintigraphy in differentiation of solitary pulmonary nodules
    Anna Płachcińska
    Department of Nuclear Medicine, Medical University, Łódź, Poland
    Nucl Med Rev Cent East Eur 7:143-50. 2004
    ....
  88. ncbi [Clinical, pathological and radiological characteristics of 83 cases of pleural tuberculoma]
    Shen Jie Tang
    Shanghai Tuberculosis Lung Key Laboratory, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai 200433, China
    Zhonghua Jie He He Hu Xi Za Zhi 32:262-5. 2009
    To investigate the clinical, pathological and radiological characteristics of pleural tuberculoma, so as to improve the understanding of this disease.
  89. ncbi Factors affecting the outcome of neuroendoscopy in patients with tuberculous meningitis hydrocephalus: a preliminary study
    Deepak Kumar Jha
    Department of Neurosurgery, St Stephens Hospital, Tishazari, Delhi 110054, India
    Surg Neurol 68:35-41; discussion 41-2. 2007
    ..In recent years, ETV has been found to be effective in patients with TBMH; however, its precise selection criteria are yet to be established. We carried out this study to identify the factors affecting the outcome of ETV in TBMH...
  90. ncbi Role of diffusion weighted imaging in differentiation of intracranial tuberculoma and tuberculous abscess from cysticercus granulomas-a report of more than 100 lesions
    Rakesh K Gupta
    Department of Radiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, MR Section, Lucknow 226014, India
    Eur J Radiol 55:384-92. 2005
    Restricted diffusion is noted in a large number of non-stroke conditions including tuberculoma. The purpose of this study was to demonstrate spectrum of diffusion weighted imaging (DWI) abnormalities in tuberculomas and tuberculous ..
  91. ncbi Abdominal tuberculosis: analysis of clinical features and outcome of adult patients in southern Taiwan
    Ming Luen Hu
    Division of Hepato Gastroenterology, Department of Internal Medicine, Chang Gung Memorial Hospital Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, Taiwan
    Chang Gung Med J 32:509-16. 2009
    ..The study was conducted at the Chang Gung Memorial Hospital-Kaohsiung, Taiwan...
  92. ncbi [Diagnosis and treatment of 11 patients with acquired immune deficiency syndrome complicated with tuberculosis of mesenteric lymph nodes.]
    Yan Liu
    Department of Infectious Diseases, Third People s Hospital of Shenzhen, Guangdong 518020, China
    Zhonghua Jie He He Hu Xi Za Zhi 32:835-7. 2009
    ..To study the clinical features of acquired immune deficiency syndrome (AIDS) complicated with tuberculosis of mesenteric lymph nodes...
  93. pmc Diagnosis of central nervous system tuberculosis by T-cell-based assays on peripheral blood and cerebrospinal fluid mononuclear cells
    Sung Han Kim
    Department of Internal Medicine, Seoul National University College of Medicine, Republic of Korea
    Clin Vaccine Immunol 15:1356-62. 2008
    ..31 (84%) showed clinical manifestations of suspected TB meningitis and 6 (16%) gave indications of intracranial tuberculoma with disseminated TB...
  94. ncbi A prospective study of seroprevalence of Toxoplasmosis in general population, and in HIV/AIDS patients in Bombay, India
    Y V Meisheri
    Department of Medicine, Seth G S Medical College, Parel, Bombay, India
    J Postgrad Med 43:93-7. 1997
    ..HIV/AIDS patients (82 men/7 women); and (iii) 25 patients (HIV negative: 12 men/13 women) treated for cerebral Tuberculoma or Neurocysticercosis during this study from January 1996-June 1997. The overall seroprevalence was 30...
  95. ncbi [Clinical analysis of completion pneumonectomy for pulmonary disease]
    Xiang hui Chu
    Department of Thoracic Surgery, Tianjin Chest Hospital, Tianjin 300051, China
    Zhonghua Wai Ke Za Zhi 45:1132-5. 2007
    ..However, in certain instances, CP offers the only chance for a cure. Now to explore the indications, prevention and management of complications as well as late outcomes of CP...
  96. ncbi Vision impairment in tuberculous meningitis: predictors and prognosis
    Manish Kumar Sinha
    Department of Neurology, Chhatrapati Shahuji Maharaj Medical University, Uttar Pradesh, Lucknow, India
    J Neurol Sci 290:27-32. 2010
    ..Vision impairment is a devastating complication of tuberculous meningitis. In the present study we evaluated the predictors and prognostic significance of vision impairment in tuberculous meningitis...
  97. ncbi Space-occupying lesions in Papua New Guinea--the CT era
    W Matui Kaptigau
    Department of Surgery, Port Moresby General Hospital, Free Mail Bag, Boroko, NCD 111, Papua New Guinea
    P N G Med J 50:33-43. 2007
    ..The use of computed tomography (CT) scanning to diagnose and treat space-occupying lesions (SOL) has been a great advance...
  98. ncbi Intracranial tuberculoma in Kuwait
    N U Abdul-Ghaffar
    Medical Department, Adan Hospital, Kuwait
    Int J Tuberc Lung Dis 2:413-8. 1998
    To study the manifestations of intracranial tuberculoma in Kuwait and to provide guidelines for the diagnosis and management of intracranial tuberculoma in developing countries, where the disease is common and facilities are limited.
  99. ncbi Endoscopic options in management of posterior third ventricular tumors
    S V Roopesh Kumar
    Department of Neurosurgery, National Institute of Mental Health and Neurosciences NIMHANS, Hosur Road, Bangalore, India
    Childs Nerv Syst 23:1135-45. 2007
    ..Most of these are associated with hydrocephalus requiring a cerebrospinal fluid diversion procedure. The present study aims to assess the effectiveness of endoscopic biopsy and third ventriculostomy (ETV) in these patients...
  100. ncbi Tubercular brain abscess--case report
    Vaishali B Dohe
    Microbiology Department, B J Medical College, Pune
    Indian J Tuberc 57:102-3. 2010
    ..CNS tuberculosis can present as meningitis, arachnoiditis, tuberculoma and brain abscess...
  101. pmc Multiple intracranial tuberculomas mimicking granulocytic sarcomas in acute myeloid leukemia
    Jae Sook Ahn
    Department of Internal Medicine, Chonnam National University Medical School, Gwangju, Korea
    J Korean Med Sci 22:S171-3. 2007
    The diagnosis of incracranial tuberculoma in immune-compromised hosts is often difficult because conventional magnetic resonance (MR) imaging of tuberculoma reveals various findings and neurologic symptoms are not typical...

Research Grants6

  1. Genetic Control of Pulmonary Cavities in Tuberculosis
    Robert Hunter; Fiscal Year: 2005
    ..If successful, new insights into the pathogenesis of pulmonary cavities may lead to specific interventions to prevent this highly infectious disease manifestation. ..
  2. IRON REGULATION & VIRULENCE--MYCOBACTERIUM TUBERCULOSIS
    YUKARI MANABE; Fiscal Year: 2003
    ..Elucidation of this iron-dependent IdeR regulon may lead to the identification of virulence determinants, and novel antigens for vaccines and therapeutics. ..
  3. Pathogen-Host Standoff: Persistent and Latent Infection
    Joanne Flynn; Fiscal Year: 2004
    ..This meeting seeks to bring together researchers from a variety of fields, with the common goal of understanding how persistent pathogens survive and how the host responds to such pathogens. ..
  4. A NON-HUMAN PRIMATE MODEL OF TUBERCULOSIS AND AIDS
    Joanne Flynn; Fiscal Year: 2004
    ..Once a non-human primate model for tuberculosis is established, it could be used to test vaccines, immunotherapy, and new treatment options for tuberculosis. ..
  5. LATENCY AND REACTIVATION TUBERCULOSIS
    YUKARI MANABE; Fiscal Year: 2006
    ..Appropriate animal models are critical to the successful development of tuberculosis vaccines, new drugs and better diagnostic tests for tuberculosis. ..
  6. Latent and Reactivation Tuberculosis
    Joanne Flynn; Fiscal Year: 2007
    ..These studies are the first to study reactivation in an immunologically tractable animal model that is similar to human latent tuberculosis. ..