intracranial tuberculoma

Summary

Summary: A well-circumscribed mass composed of tuberculous granulation tissue that may occur in the cerebral hemispheres, cerebellum, brain stem, or perimeningeal spaces. Multiple lesions are quite common. Management of intracranial manifestations vary with lesion site. Intracranial tuberculomas may be associated with SEIZURES, focal neurologic deficits, and INTRACRANIAL HYPERTENSION. Spinal cord tuberculomas may be associated with localized or radicular pain, weakness, sensory loss, and incontinence. Tuberculomas may arise as OPPORTUNISTIC INFECTIONS, but also occur in immunocompetent individuals.

Top Publications

  1. ncbi Solitary pontine tuberculoma
    Hiroshi Sugimori
    Cerebrovascular Department, Neuroscience Institute, St Mary Hospital, Kurume
    Intern Med 41:738-42. 2002
  2. ncbi Multiple meningeal tuberculomas recurring after 18-month anti-tuberculous chemotherapy--case report
    Hideo Takeshima
    Department of Neurosurgery, Faculty of Medicine, Kagoshima University, Kagoshima, Japan
    Neurol Med Chir (Tokyo) 44:133-7. 2004
  3. ncbi [Multiple brain tuberculomas]
    Tomasz Piorunek
    Katedra i Klinika Ftyzjopneumonologii AM im K Marcinkowskiego w Poznaniu
    Pol Arch Med Wewn 114:1220-5. 2005
  4. ncbi [Neurotuberculosis: a continuing clinical challenge]
    B M Mackert
    Klinik fur Neurologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Nervenarzt 79:153-66. 2008
  5. ncbi Brain CT and MRI findings in 100 consecutive patients with intracranial tuberculoma
    Mohammad Wasay
    Department of Neurology, Aga Khan University, Stadium Road, Karachi 74800, Pakistan
    J Neuroimaging 13:240-7. 2003
  6. ncbi Intracranial tuberculoma in Kuwait
    N U Abdul-Ghaffar
    Medical Department, Adan Hospital, Kuwait
    Int J Tuberc Lung Dis 2:413-8. 1998
  7. ncbi Role of diffusion weighted imaging in differentiation of intracranial tuberculoma and tuberculous abscess from cysticercus granulomas-a report of more than 100 lesions
    Rakesh K Gupta
    Department of Radiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, MR Section, Lucknow 226014, India
    Eur J Radiol 55:384-92. 2005
  8. ncbi Paradoxical intracranial tuberculoma requiring surgical treatment
    N Serdar Bas
    Department of Neurosurgery, SSK Vakif Gureba Training Hospital, Istanbul, Turkey
    Pediatr Neurosurg 41:201-5. 2005
  9. ncbi Retrospective study of 23 pathologically proven cases of central nervous system tuberculomas
    Cicek Bayindir
    Department of Pathology, Division of Neuropathology, Istanbul Faculty of Medicine, Istanbul University, Temel Bilimler Binasi, 34390 Capa, Istanbul, Turkey
    Clin Neurol Neurosurg 108:353-7. 2006
  10. ncbi Intracranial multiple tuberculomas: 2 unusual cases
    Aslan Guzel
    Department of Neurosurgery, Faculty of Medicine, Dicle University, 21180 Diyarbakr, Turkey
    Surg Neurol 64:S109-12. 2005

Detail Information

Publications151 found, 100 shown here

  1. ncbi Solitary pontine tuberculoma
    Hiroshi Sugimori
    Cerebrovascular Department, Neuroscience Institute, St Mary Hospital, Kurume
    Intern Med 41:738-42. 2002
    ..An empiric administration of antituberculous drug may be an important and non-invasive diagnostic tool as well as a treatment in such cases...
  2. ncbi Multiple meningeal tuberculomas recurring after 18-month anti-tuberculous chemotherapy--case report
    Hideo Takeshima
    Department of Neurosurgery, Faculty of Medicine, Kagoshima University, Kagoshima, Japan
    Neurol Med Chir (Tokyo) 44:133-7. 2004
    ..Tuberculoma should be included in the differential diagnosis of enhanced intracranial mass lesions. Anti-tuberculous therapy may require extended periods of up to 36 months to stabilize the disease...
  3. ncbi [Multiple brain tuberculomas]
    Tomasz Piorunek
    Katedra i Klinika Ftyzjopneumonologii AM im K Marcinkowskiego w Poznaniu
    Pol Arch Med Wewn 114:1220-5. 2005
    ..Basing on the described case, current possibilities of tuberculoma diagnostic difficulties, caused by unspecific clinical manifestation and atypical radiological lesions, was drawn...
  4. ncbi [Neurotuberculosis: a continuing clinical challenge]
    B M Mackert
    Klinik fur Neurologie, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Nervenarzt 79:153-66. 2008
    ..Resistant new strains of the pathogen, Mycobacterium tuberculosis, complicate therapy. Recent discoveries especially in diagnosis and therapy are explained using case evidence...
  5. ncbi Brain CT and MRI findings in 100 consecutive patients with intracranial tuberculoma
    Mohammad Wasay
    Department of Neurology, Aga Khan University, Stadium Road, Karachi 74800, Pakistan
    J Neuroimaging 13:240-7. 2003
    The characteristics of intracranial tuberculoma on computed tomography (CT) and magnetic resonance imaging (MRI) are not well known. The authors reviewed the features of tuberculoma on CT scans and MRI...
  6. ncbi Intracranial tuberculoma in Kuwait
    N U Abdul-Ghaffar
    Medical Department, Adan Hospital, Kuwait
    Int J Tuberc Lung Dis 2:413-8. 1998
    To study the manifestations of intracranial tuberculoma in Kuwait and to provide guidelines for the diagnosis and management of intracranial tuberculoma in developing countries, where the disease is common and facilities are limited.
  7. ncbi Role of diffusion weighted imaging in differentiation of intracranial tuberculoma and tuberculous abscess from cysticercus granulomas-a report of more than 100 lesions
    Rakesh K Gupta
    Department of Radiology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, MR Section, Lucknow 226014, India
    Eur J Radiol 55:384-92. 2005
    ..We conclude that addition of DWI to routine imaging protocol may help in differentiation of tuberculous lesions from degenerating cysticercus granuloma...
  8. ncbi Paradoxical intracranial tuberculoma requiring surgical treatment
    N Serdar Bas
    Department of Neurosurgery, SSK Vakif Gureba Training Hospital, Istanbul, Turkey
    Pediatr Neurosurg 41:201-5. 2005
    ..She was followed with dexamethasone treatment in addition to antituberculous therapy for 2 months. Then, the lesion was removed because it had increased in size in spite of appropriate chemotherapy...
  9. ncbi Retrospective study of 23 pathologically proven cases of central nervous system tuberculomas
    Cicek Bayindir
    Department of Pathology, Division of Neuropathology, Istanbul Faculty of Medicine, Istanbul University, Temel Bilimler Binasi, 34390 Capa, Istanbul, Turkey
    Clin Neurol Neurosurg 108:353-7. 2006
    ..It presents as meningitis or tuberculoma. Tuberculoma is a granulomatous inflammatory process mimicking a neoplasm radiologically, so usually a biopsy is performed...
  10. ncbi Intracranial multiple tuberculomas: 2 unusual cases
    Aslan Guzel
    Department of Neurosurgery, Faculty of Medicine, Dicle University, 21180 Diyarbakr, Turkey
    Surg Neurol 64:S109-12. 2005
    ..Only 1% of patients with TB develop an intracranial tuberculoma (Tbm), usually as part of miliary TB...
  11. ncbi [Serial MRI findings of intracranial tuberculomas: a case report and review of the literature]
    Jun Tsugawa
    Department of Neurology, Kawanami Hospital
    No To Shinkei 58:225-30. 2006
    b>Intracranial tuberculoma is an infectious disorder, occurring with or without tuberculous meningitis...
  12. ncbi [Brain tuberculomas and paradoxical expansion]
    F L Lado Lado
    Rev Clin Esp 205:94-5. 2005
  13. ncbi Pituitary tuberculoma: magnetic resonance imaging
    S Singh
    Department of Radiodiagnosis and Imaging, Christian Medical College and Hospital, Vellore 632004, India
    Neurol India 51:548-50. 2003
    ..The patient was treated with anti-tuberculous chemotherapy, and a follow-up MRI after 6 months showed good response. The relevant literature is briefly reviewed...
  14. ncbi Disseminated mycobacterium bovis infection in an immunocompetent host
    Niels Schübel
    Department of Internal Medicine III, University of Lubeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    Eur J Med Res 11:163-6. 2006
    ..We reviewed the data of our microbiological department and found five other patients with Mycobacterium bovis infection diagnosed between 1999 and 2004, which are 5.8 % of all diagnoses of tuberculosis during this period...
  15. ncbi Giant cerebellar tuberculoma mimicking a malignant tumour
    S I Poonnoose
    Department of Neurological Sciences, Christian Medical College and Hospital, 632004 Vellore, India
    Neuroradiology 46:136-9. 2004
    ..We highlight the need to integrate different imaging modalities in arriving at a diagnosis of an intracranial mass and discuss atypical features of intracranial tuberculomas...
  16. ncbi Isolated brain stem tuberculoma presenting with one and a half syndrome
    Mushira Enani
    Department of Medicine, Division of Infectious Diseases, Riyadh Military Hospital, PO Box 7897, Riyadh 11159, Kingdom of Saudi Arabia
    Saudi Med J 27:1407-11. 2006
    ..Recovery was achieved 8 weeks after initiation of anti-tuberculous anti-TB therapy. The isolated nature of the tuberculoma and the association with this rare syndrome is highlighted...
  17. ncbi Intracranial tuberculomas: the Hofuf, Saudi Arabia experience
    M M El-Sayed
    The King Fahad Hospital, Hofuf, Saudi Arabia
    Afr J Med Med Sci 35:21-7. 2006
    ..presents with seizures with or without headache, he should have a brain CT scan with contrast to exclude intracranial Tuberculoma. A short course of anti-tuberculous therapy may be tried where there is doubt, irrespective of normal ..
  18. ncbi Irreversible blindness due to multiple tuberculomas in the suprasellar cistern
    Kumudini Sharma
    Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow U P 226014, India
    J Neuroophthalmol 23:211-2. 2003
    ..There was no evidence of tuberculosis elsewhere in the body. Standard antituberculous treatment, including corticosteroids, did not reverse the blindness...
  19. ncbi Tuberculoma of the brain: a series of 16 cases treated with anti-tuberculosis drugs
    M N A Idris
    Faculty of Medicine, University of Khartoum, Khartoum, Sudan
    Int J Tuberc Lung Dis 11:91-5. 2007
    To describe the clinical presentation, radiological findings and outcome of treatment with antituberculosis drugs in 16 cases of intracranial tuberculoma.
  20. ncbi [Aseptic cerebral venous thrombosis and multiple cerebral tuberculomas associated with pulmonary miliary tuberculosis]
    O Messouak
    Service de Neurologie, CHU Hassan II, Fes, Maroc
    Rev Neurol (Paris) 163:238-40. 2007
    ..Severe pulmonary tuberculosis may be complicated by deep vein thrombosis due to a state of hypercoagulability...
  21. ncbi Solitary choroid plexus tuberculoma in an adult patient. Case illustration
    Francesco Doglietto
    Institutes of Neurosurgery, Pathology, and Microbiology, Catholic University School of Medicine, Rome, Italy
    J Neurosurg 105:933. 2006
  22. ncbi Paradoxical reaction during treatment of tuberculous brain abscess in a patient with AIDS
    Jose E Vidal
    Rev Inst Med Trop Sao Paulo 45:177-8. 2003
  23. ncbi [Pseudotumoral form of sclerochoroidal tuberculosis: a case report]
    S Semlali
    Service de Neuroradiologie, Hopital des specialites, CHU, Rabat, Morocco
    J Radiol 85:131-4. 2004
    ..Ocular tuberculosis is rare, especially the pseudotumoral form. It can simulate a choroidal tumor. Radiologists should be familiar with this appearance because the lesion is reversible with antituberculous treatment...
  24. ncbi Orbital tuberculoma extending into the cranium
    Taru Dewan
    Department of Ophthalmology, Dr Ram Manohar Lohia Hospital, New Delhi, India
    Ophthalmologica 220:137-9. 2006
    ..Histopathology of the excised lesion confirmed tuberculosis. The case is reported to highlight both the rare presentation as well as remarkable visual recovery in a patient with orbital tuberculosis...
  25. pmc Cerebral tuberculoma
    P Dennison
    Oxford Chest Unit, Churchill Hospital, Oxford OX3 7LJ, UK
    Thorax 61:922. 2006
  26. ncbi Solitary intracranial tuberculoma in patients without immuno-suppression: a report of three cases
    A A Adeolu
    Department of Surgery, College of Health Sciences, Obafemi Awolowo University, Ile Ife, and University of Ibadan College Hospital, Nigeria
    Niger Postgrad Med J 13:69-72. 2006
    ..In this article, we report 3 patients who had solitary brain tuberculomas and were otherwise healthy to underscore the importance of continuing vigilance for this disease...
  27. ncbi Concurrent intramedullary and intracerebral tuberculomas
    S N Shenoy
    Neurol India 52:514-6. 2004
  28. ncbi Central nervous system tuberculosis and paradoxical response
    Mohammad Wasay
    South Med J 99:331-2. 2006
  29. ncbi Development of tuberculoma during therapy presenting as hemianopsia
    Ming Han Tsai
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children s Hospital, Taoyuan, Taiwan
    Pediatr Neurol 31:360-3. 2004
    ..Development of intracranial tuberculoma during antituberculous therapy, although rare, dose not represent treatment failure, and continuation of ..
  30. ncbi Cerebral tuberculomas in AIDS patients: a forgotten diagnosis?
    Jose E Vidal
    Department of Infectology, Institute of Infectious Disease Emilio Ribas, Sao Paulo SP, Brazil
    Arq Neuropsiquiatr 62:793-6. 2004
    ..Despite of their infrequent presentation, tuberculomas should be considered in the differential diagnosis of cerebral expansive lesions in patients with AIDS...
  31. ncbi Paradoxically developed optochiasmatic tuberculoma and tuberculous lymphadenitis: a case report with 18-month follow up by MRI
    Ahmet Kalkan
    Department of Infectious Diseases, Radiology, Immunology and Ophthalmology, Firat University Medical School, Elazig, TR23119 Turkey
    South Med J 99:388-92. 2006
    ..the first case ofextracranial tuberculous lymphadenitis which paradoxically developed during treatment of intracranial tuberculoma. Our patient, a 15-year-old girl who initially presented with meningitis and intracranial tuberculomas, ..
  32. ncbi [Tuberculoma complicating tuberculous meningitis: description of one paediatric case]
    C Ruggeri
    U O di Clinica Pediatrica, Dipartimento di Scienze Pediatriche Mediche e Chirurgiche, Universita degli Studi di Messina, Messina
    Minerva Pediatr 57:329-32. 2005
    b>Intracranial tuberculoma is a possible complication of meningeal, miliary or pulmonary tuberculosis. In developing countries it represents 30% of space-occupying intracranial lesions, in industrialised countries only 0.1-0.2%...
  33. ncbi [Treatment of tuberculous meningitis]
    O Steichen
    Service de Neurologie, Centre Hospitalier Delafontaine, Saint Denis
    Rev Neurol (Paris) 162:581-93. 2006
    ..Tuberculous meningitis and brain tuberculomas are currently rare in the western world but remain serious. Improved outcome requires early recognition and treatment of these conditions...
  34. ncbi [Symptomatic intracranial tuberculoma revealed when the patient receiving therapy for miliary tuberculosis: a case report]
    Yücel Taşan
    Gulhane Medical Academy, Pulmonary Diseases, Ankara, Turkey
    Tuberk Toraks 51:298-302. 2003
    ....
  35. ncbi Intracranial tuberculomas mimicking a malignant disease in an immunocompetent patient
    A Giese
    Department of Neurosurgery, University Hospital Luebeck, Luebeck, Germany
    Acta Neurochir (Wien) 145:513-7; discussion 517. 2003
    ..Because a tuberculoma is rarely suspected especially if there is atypical morphology, biopsy is required to establish the diagnosis and expedite specific treatment...
  36. ncbi [Disseminated granulomatous disease: sarcoidosis or tuberculosis?]
    J Canora Lebrato
    Servicio de Medicina Interna, Hospital de Fuenlabrada, Madrid, Espana
    Rev Clin Esp 207:408-10. 2007
  37. ncbi Miliary lung lesions and multiple intracranial tumors in a 26-year-old woman
    Shih Feng Liu
    Division of Chest Medicine, Department of Internal Medicine, Chang Gung Memorial Hospital, Kaohsiung Hsien, Taiwan, ROC
    Respiration 69:471-2. 2002
  38. ncbi [Case report: evaluation of two cases of tuberculoma incident to tuberculosis meningitis]
    Salih Cesur
    Ankara Üniversitesi Tıp Fakültesi, Klinik Bakteriyoloji ve Infeksiyon Hastaliklari Anabilim Dali, Ankara
    Mikrobiyol Bul 36:91-4. 2002
    b>Intracranial tuberculoma is one of the most serious complications of tuberculous meningitis. In this report, two patients who develop intracranial tuberculoma as a complication of tuberculous meningitis have been presented...
  39. ncbi [Miliary tuberculosis and intramedullary tuberculoma of the conus medullaris]
    H Korri
    Service de Neurologie Hôtel Dieu de France, Beyrouth, Liban
    Rev Neurol (Paris) 163:1106-8. 2007
    ..This case is presented to illustrate the diagnostic and therapeutic dilemmas of a rare condition: intramedullary tuberculoma of the conus medullaris...
  40. ncbi Intraocular tuberculosis mimicking retinoblastoma: a case report
    Seema Sen
    Diagn Cytopathol 28:107-9. 2003
  41. ncbi Tuberculosis clinical grand round
    A Bajpayee
    Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India
    Indian J Pediatr 70:57-61. 2003
  42. doi Re: Rate of resolution of histologically verified intracranial tuberculomas
    Manas Kumar Panigrahi
    Neurosurgery 56:E629. 2005
  43. ncbi [Imaging features of CNS tuberculosis]
    S Semlali
    Service d Imagerie Medicale, hôpital militaire d instruction Mohamed V, Rabat, Morocco
    J Radiol 89:209-20. 2008
    ..Even though non-specific, MRI including diffusion-weighted imaging and proton spectroscopy is more sensitive than CT for detection of some lesions. The purpose of this paper is to illustrate the imaging features of CNS tuberculosis...
  44. ncbi Intracranial and spinal tuberculosis requiring neurosurgical intervention. The Wellington Hospital experience 1998-2001
    B Darwish
    Department of Neurosurgery, Wellington Hospital
    N Z Med J 114:445-7. 2001
    ..Management is prolonged and often complex, and close co-operation is required between the neurosurgical team and a physician experienced in the management of tuberculosis...
  45. ncbi Pituitary tuberculosis mimicking idiopathic granulomatous hypophysitis
    Nuzhat Husain
    Department of Pathology, King George s Medical University, Lucknow, 226003, India
    Pituitary 11:313-5. 2008
    ....
  46. ncbi [Neuroradiologic manifestations of central nervous system tuberculosis in 122 adults]
    B Kilani
    Service des Maladies Infectieuses, Hopital La Rabta, 1007 Jebbari, Tunis, Tunisie
    Rev Med Interne 24:86-96. 2003
    ..Central nervous system (CNS) tuberculosis remains a public health problem, particularly in developing countries. The aim of this study is to characterize neuroradiologic findings of various intracranial lesions...
  47. ncbi Suprasellar tuberculoma presenting with diabetes insipidus and hypothyroidism--a case report
    R Jain
    Department of Radiodiagnosis, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow-226014, India
    Neurol India 49:314-6. 2001
    ..The patient responded well to antituberculous treatment and an unnecessary surgery was avoided...
  48. ncbi Concurrent syringomyelia and intradural extramedullary tuberculoma as late complications of tuberculous meningitis
    N Muthukumar
    Deparment of Neurosurgery, Madurai Medical College, Madurai, India
    J Clin Neurosci 14:1225-30. 2007
    ..The pathogenesis of syringomyelia in this condition is discussed...
  49. pmc Diagnosis of central nervous system tuberculosis by T-cell-based assays on peripheral blood and cerebrospinal fluid mononuclear cells
    Sung Han Kim
    Department of Internal Medicine, Seoul National University College of Medicine, Republic of Korea
    Clin Vaccine Immunol 15:1356-62. 2008
    ..these, 31 (84%) showed clinical manifestations of suspected TB meningitis and 6 (16%) gave indications of intracranial tuberculoma with disseminated TB...
  50. pmc Spectrum of intracranial parenchymal lesions in patients with human immunodeficiency virus infection in the Republic of Korea
    Pyoeng Gyun Choe
    Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea
    J Korean Med Sci 25:1005-10. 2010
    ..leukoencephalopathy (12 patients) is the most frequent intracranial parenchymal lesions, followed by intracranial tuberculoma (7 patients), primary central nervous system lymphoma (7 patients), intracranial cryptococcoma (4 ..
  51. ncbi [A case of cerebellar tuberculoma]
    Daisuke Tanioka
    Department of Neurosurgery, Showa University School of Medicine, 1 5 8 Hatanodai, Shinagawa ku, Tokyo, Japan
    No Shinkei Geka 33:919-23. 2005
    ..Histological examination revealed tuberculoma when there are no abnormal data. The intracranial tuberculoma may be confused with an intracranial neoplasm...
  52. ncbi En plaque intradural extramedullary spinal tuberculoma and concurrent intracranial tuberculomas: paradoxical response to antituberculous therapy. Case report
    Natarajan Muthukumar
    Department of Neurosurgery, Madurai Medical College, Madurai, India
    J Neurosurg Spine 6:169-73. 2007
    ..The patient's condition responded well to this treatment. Although the appearance of intracranial tuberculoma as a paradoxical response to chemotherapy has been previously reported, no authors have reported on the ..
  53. ncbi Coexistence between meningioma and tuberculosis: case report
    Martha Tena-Suck
    Department of Neuropathology, National Institute of Neurology and Neurosurgery Manuel Velasco Suarez, Av Insurgentes Sur no 3788 Col La fama, Delegacion Tlalpan, cp 14269 Mexico, DF, Mexico
    J Neurooncol 99:289-94. 2010
    b>Intracranial tuberculoma generally presents as either solitary or multiple lesions in the brain parenchyma. These are characterized by a ring-enhancing area on either computerized tomography scans or magnetic resonance images...
  54. ncbi Early detection of central nervous system tuberculosis with the gen-probe nucleic Acid amplification assay: utility in an inner city hospital
    Cristina A Baker
    Department of Medicine, Hennepin County Medical Center, Minneapolis, MN, 55415, USA
    Clin Infect Dis 35:339-42. 2002
    ..We investigated the utility of the Gen-Probe nucleic acid amplification assay for the rapid diagnosis of tuberculous meningitis and as a noninvasive method of identifying intracranial tuberculoma.
  55. ncbi Clinicopathological study of tuberculous brain abscess
    Shrijeet Chakraborti
    Department of Neuropathology, National Institute of Mental Health and Neurosciences, Hosur Road, Bangalore 560029, Karnataka, India
    Pathol Res Pract 205:815-22. 2009
    ..A high index of clinical suspicion is necessary particularly in countries endemic for tuberculosis to ensure an accurate diagnosis and application of an appropriate therapy...
  56. ncbi Two unusual sequelae of tuberculous meningitis despite treatment
    Allen J Blaivas
    Division of Pulmonary and Critical Care Medicine and the National Tuberculosis Center, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA
    South Med J 98:1028-30. 2005
    ..These manifestations were successfully treated with the addition of corticosteroids to the antituberculous regimen. The typical clinical presentations of these diseases are reviewed and various means of pathogenesis proposed...
  57. ncbi British Infection Society guidelines for the diagnosis and treatment of tuberculosis of the central nervous system in adults and children
    Guy Thwaites
    Centre for Molecular Microbiology and Infection, Imperial College, Exhibition Road, South Kensington, London, UK
    J Infect 59:167-87. 2009
    ..The co-administration of anti-retroviral and anti-tuberculosis drugs should follow guidance issued by the British HIV association (www.bhiva.org)...
  58. ncbi Brainstem tuberculoma in a postpartum patient
    A Akhaddar
    J Neuroradiol 34:345-6. 2007
  59. ncbi Flare up of tuberculous abscess following stereotactic aspiration--case report
    Ketan Desai
    Department of Neurosurgery, King Edward Memorial Hospital, Seth G S Medical College, Parel, Mumbai, India
    Neurol Med Chir (Tokyo) 42:147-9. 2002
    ..The daughter abscesses were removed via craniotomy. Stereotactic aspiration requires care to prevent such flare up of the disease...
  60. ncbi Chronic brain abscess secondary to a retained wooden foreign body: diagnostic and management dilemmas
    Ravi Dadlani
    Department of Neurosurgery, Sri Satya Sai Institute of Higher Medical Sciences, Bangalore, India
    Indian J Pediatr 77:575-6. 2010
    ..She was operated for a suspected intracranial tuberculoma and was found to harbor an intra-parenchymal retained wooden foreign body with a chronic abscess...
  61. ncbi Intracranial tuberculoma with adjacent inflammatory aneurysms
    In Young Kim
    Brain Tumor Clinic and Gamma Knife Center, Department of Neurosurgery, Chonnam National University, Hwasun Hospital, 160 Ilsimri, Hwasun eup, Hwasun Gun, Chonnam 519 809, Republic of Korea
    J Clin Neurosci 15:1174-6. 2008
    We describe for the first time a case of intracranial tuberculoma with adjacent intracerebral inflammatory aneurysms, and include a brief discussion of the developmental mechanism of these pathologies...
  62. ncbi [Cerebelous syndrome by infratentorial brain tuberculornas and mutisystemic tuberculosis in AIDS patient]
    Claudio Navarrete A
    Servicio de Neurologia y Neurocirugia, Hospital Clínico Regional de Valdivia, Valdivia, Chile
    Rev Chilena Infectol 25:122-6. 2008
    ..The clinical case scenario of infratentorial tuberculomas without meningitis as a first manifestation of TB and AIDS is unusual, generating our interest in reporting this case...
  63. ncbi An unusual intraventricular lesion: tuberculoma
    G Sonmez
    J Neuroradiol 35:63-4. 2008
  64. ncbi Intracranial tuberculomas in an immunocompetent patient mimicking brain metastasis of unknown origin
    A P Zavascki
    Infection 34:181-2. 2006
  65. ncbi Images in clinical medicine. Cerebral tuberculoma
    Juan Carlos Cataño
    University of Antioquia Medical School, Medellin, Colombia
    N Engl J Med 357:2166. 2007
  66. ncbi Cerebral tuberculoma presenting as flexion spasms
    Cristina L Martins
    Neuropediatric Unit, Pediatric Department, Hospital Garcia de Orta, Almada, Portugal
    Pediatr Infect Dis J 26:83-4. 2007
    ..After antituberculous therapy, the outcome was favorable. Despite all investigations, Mycobacterium tuberculosis's mode of transmission was unclear, and both congenital and postnatal acquired forms were considered...
  67. ncbi Corticobasal syndrome due to a thalamic tuberculoma and focal cortical atrophy
    K R Mridula
    Department of Neurology, Nizam s Institute of Medical Sciences, Punjagutta, Hyderabad, India 500082
    J Neurol Neurosurg Psychiatry 79:107-8. 2008
  68. ncbi Brainstem tuberculoma in the immunocompetent: case report and literature review
    Soma Sahaiu-Srivastava
    Department of Neurology, University of Southern California, Los Angeles, United States
    Clin Neurol Neurosurg 110:302-4. 2008
    ..We conclude that a high index of suspicion is essential to make an early diagnosis of intracranial tuberculoma, since often, traditional TB tests like PPD and sputum examinations can be negative.
  69. ncbi A new presentation of immune reconstitution inflammatory syndrome followed by a severe paradoxical reaction in an HIV-1-infected patient with tuberculous meningitis
    Justine Dautremer
    AIDS 21:381-2. 2007
  70. ncbi MRI findings of intracranial tuberculomas
    Guner Sonmez
    Department of Radiology, GATA Haydarpasa Teaching Hospital, Istanbul, Turkey
    Clin Imaging 32:88-92. 2008
    ..The aim of this study was to characterize the magnetic resonance imaging (MRI) findings of intracranial tuberculoma, a form of neurotuberculosis.
  71. ncbi Disseminated tuberculosis with multiple intracerebral tuberculomas in a patient with anorexia nervosa
    Jung Yong Ahn
    Department of Neurosurgery, Yonsei University College of Medicine, Seoul, South Korea
    Int J Eat Disord 40:288-91. 2007
    ..The malnutrition resulted from anorexia nervosa may contribute to the significant impairment of immunity. The authors present a 23-year-old female patient initially diagnosed with anorexia nervosa...
  72. pmc [[The intracranial tuberculoma: report of 125 cases]]
    Faycal Moufid
    Service de Neurochirurgie, CHR Al Farrabi, Faculté de Médecine Oujda, Maroc
    Pan Afr Med J 12:56. 2012
    ..Ceci s'est accompagné d'une réduction significative de mortalité a 1,4% (p = 0,0003) et de morbidité a 2% (p = 0,0027)...
  73. ncbi [Manifestations and diagnosis of extrapulmonary tuberculosis]
    S Stelianides
    , , Paris
    Rev Mal Respir 14:S72-87. 1997
    ..The mortality and morbidity remain elevated in developing counties as in industrialised counties and clinical situations in which extra pulmonary tuberculosis occur often worsen the prognosis...
  74. ncbi Tuberculous pseudoaneurysm of the ascending aorta associated with intracranial tuberculoma
    O Shigemitsu
    Department of Cardiovascular Surgery, Oita Medical University, Hasamamachi, Oita, Japan
    J Cardiovasc Surg (Torino) 43:59-62. 2002
    ..of tuberculous pseudoaneurysm of the ascending aorta which developed 7 months after the onset of multiple intracranial tuberculoma in a 59-year-old man...
  75. pmc Coexistent cranial tuberculomas and tuberculosis of the cervix in a postmenopausal woman
    R Bhatia
    Sex Transm Infect 79:496-7. 2003
  76. ncbi [Multiple cerebral tuberculomas]
    L Noriega
    Departamento de Medicina Interna, Servicio de Neurologia, Hospital Regional Doctor Rafael Hernández, David, Panama
    Rev Neurol 37:531-5. 2003
    ..Its presentation as tuberculomas cerebral manifold at level of the central nervous system is little frequent in immunocompetent patients and can be confused with other etiology...
  77. ncbi Intraventricular tuberculoma
    Ketan Desai
    Department of Neurosurgery, King Edward Memorial Hospital, Seth G S Medical College, Parel, Mumbai, India
    Neurol Med Chir (Tokyo) 42:501-3. 2002
    ..The patient was asymptomatic at 9 months. Ventricular involvement in neurotuberculosis is rare, but should be considered in the presence of other indicators of tuberculous infection...
  78. ncbi Miliary tuberculosis associated with multiple intracranial tuberculomas
    Erkan Ceylan
    Department of Chest Diseases, Harran University, Faculty of Medicine, Sanliurfa, Turkey
    Tohoku J Exp Med 205:367-70. 2005
    ..The significance of our case is due to the presence of both the miliary tuberculosis and intracranial tuberculomas. The patient was admitted to the hospital due to central nervous system symtoms rather than pulmonary symptoms...
  79. ncbi Rate of resolution of histologically verified intracranial tuberculomas
    Santosh Isaac Poonnoose
    Department of Neurological Sciences, Christian Medical College and Hospital, Vellore, India
    Neurosurgery 53:873-8; discussion 878-9. 2003
    ..The effects of the size of the tuberculomas, the number of tuberculomas, and the addition of corticosteroid therapy on the rate of resolution of the tuberculomas were also studied...
  80. ncbi [Cerebral tuberculomas]
    M Fredj
    Service de Neurologie, EPS Charles Nicolle, Tunis, Tunisie
    Rev Neurol (Paris) 159:795-8. 2003
    ....
  81. ncbi Solitary intracranial tuberculoma mimicking a malignant tumor in a patient without tubercular lesions or a history of disease: a case report
    Javier A Bustamante-Rengifo
    Population Based Cali Cancer Registry, Department of Pathology, School of Medicine, Universidad del Valle, Street 4 B No 36 00, Building 116 4th Floor, 760043 Cali, Colombia
    Bosn J Basic Med Sci 13:129-33. 2013
    ..Intracranial masses are frequently targeted as a malignant neoplastic disease for surgical treatment. Considering an infectious etiology must be a diagnostic option...
  82. ncbi Case 16-2003 - brain abscess
    Munib Mundia
    N Engl J Med 349:1004-6; author reply 1004-6. 2003
  83. ncbi Fatal hemorrhagic intracranial TB in a renal transplant recipient despite INH prophylaxis
    Nasrulla Abutaleb
    Department of Nephrology, North West Armed Forces Hospital, Tabuk, Saudi Arabia
    Saudi J Kidney Dis Transpl 18:594-8. 2007
    ..Intracranial hemorrhage was drained and tissue staining revealed heavy loads of tuberculus (TB) bacilli. The patient died two weeks later from septic shock with multi-organ failure...
  84. ncbi Cavernous sinus tuberculoma: diagnostic difficulties in a personal case
    R Rebai
    Department of Neurological Surgery, H. Bourguiba Hospital, Sfax, Tunisia
    Surg Neurol 55:372-5. 2001
    ..CONCLUSION: The diagnosis of a cavernous sinus tuberculoma is difficult; it is confirmed by biopsy. However, a trial of medical treatment, if the results are favorable, may obviate the need for a surgical procedure...
  85. pmc Relationship between intracranial granulomas and cerebrospinal fluid levels of gamma interferon and interleukin-10 in patients with tuberculous meningitis
    Adel M Mansour
    University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Clin Diagn Lab Immunol 12:363-5. 2005
    ..Cytokine levels did not predict intracranial granuloma (IG) development, but IFN-gamma levels in the top quartile after 1 month of therapy were highly associated (odds ratio = 18) with detection of an IG by computed tomography scanning...
  86. ncbi [Diagnostic image (309). An Indonesian woman with headache, confusion and fever]
    D J Nieuwkamp
    Universitair Medisch Centrum Utrecht, afd Neurologie, Postbus 85 500, 3508 GA Utrecht
    Ned Tijdschr Geneeskd 151:299. 2007
    ..A 30-year-old Indonesian woman presented with headache, confusion, vomiting, diplopia and fever, due to multiple intracranial tuberculomata...
  87. ncbi Case report: one-and-a-half-syndrome and tuberculosis of the pons in a patient with AIDS
    A Minagar
    Department of Neurology, University of Miami, Florida, USA
    AIDS Patient Care STDS 14:461-4. 2000
    ..The patient had complete recovery after anti-tuberculosis treatment. The nuclear location of the tuberculoma is unusual and the reversal of this neuro-ophthalmologic syndrome is noteworthy...
  88. ncbi Imaging meningo-encephalic tuberculosis
    Carlos Morgado
    Department of Neuroradiology, Hospital de Santa Maria, Universidade de Lisboa, Avenida Prof Egas Moniz, 1649 035 Lisboa, Portugal
    Eur J Radiol 55:188-92. 2005
    ..A high index of suspicion in the appropriate clinical and laboratorial setting may promote rapid diagnosis and institution of therapeutic measures that avoid death or serious neurological consequences...
  89. ncbi Comparative evaluation of magnetization transfer MR imaging and in-vivo proton MR spectroscopy in brain tuberculomas
    Rakesh K Gupta
    Department of Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow 226014, India
    Magn Reson Imaging 20:375-81. 2002
    ..We conclude that T1 weighted MT MR imaging appears to be more consistent in the tissue characterization of brain tuberculomas...
  90. ncbi Multifocal Epstein-Barr virus-associated smooth muscle tumor in adults with AIDS: case report and review of the literature
    S Gallien
    Department of Infectious Disease, Saint Louis Hospital and University Paris 7, Paris, France
    Oncology 74:167-76. 2008
    ..The aim of this study was to provide a systematic review of Epstein-Barr virus-associated smooth muscle tumors (EBV-SMT) in human immunodeficiency virus (HIV)-infected adults, focusing on clinical and histopathologic features and outcome...
  91. ncbi Isoniazid- and streptomycin-resistant miliary tuberculosis complicated by intracranial tuberculoma in a Japanese infant
    Naruhiko Ishiwada
    Division of Control and Treatment of Infectious Diseases, Chiba University Hospital, Chiba City, Chiba, Japan
    Tohoku J Exp Med 229:221-5. 2013
    ..The incidence of drug-resistant TB is increasing in many areas of the world. Continuous monitoring for pediatric patients with drug-resistant TB is therefore needed...
  92. ncbi Paradoxical reaction of multiple cerebral tuberculomas
    Carolina Garcia-Vidal
    Infectious Disease Service, Institut d Investigació Biomèdica de Bellvitge IDIBELL, Hospital Universitari de Bellvitge, Barcelona, Spain
    Mayo Clin Proc 83:264. 2008
  93. ncbi [Multiple cerebral tuberculomas presenting with paradoxical expansion: a case report]
    K Gotoh
    Division of Neurosurgery, Takeda General Hospital, 28-1 Moriminami-cho, Ishida, Fushimi-ku, Kyoto 601-1415, Japan
    No Shinkei Geka 29:1075-9. 2001
    ..We report successful treatment of a case of multiple tuberculomas presenting with paradoxical expansion managed by a combination of surgery and continuous chemotherapy...
  94. ncbi Nocardia brain abscess in a diabetic patient
    Prithwiraj Chakrabarti
    Department of Microbiology, Advanced Medicare Research Institute AMRI Hospitals, Kolkata, India
    Indian J Pathol Microbiol 51:151-3. 2008
    ..A high index of suspicion and early intervention like stereotactic brain biopsy remain the cornerstone to increase the chance of positive clinical outcome...
  95. ncbi A "bunch of grapes" intracranial tuberculoma
    Vivek Jain
    Division of Pediatric Neurology, Department of Pediatrics, Advanced Pediatric Centre, PGIMER, Chandigarh, India
    Neurology 59:1111. 2002
  96. ncbi Assessment of therapeutic response in brain tuberculomas using serial dynamic contrast-enhanced MRI
    M Haris
    Department of Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India
    Clin Radiol 63:562-74. 2008
    ..To assess the most useful dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) index in the evaluation of the therapeutic response in brain tuberculoma (BT) patients...
  97. ncbi Intrasellar tuberculoma presenting as pituitary apoplexy
    M J Arunkumar
    Department of Neurological Sciences, Christian Medical College and Hospital, Vellore - 632 004, Tamilnadu, India
    Neurol India 49:407-10. 2001
    ..Intrasellar tuberculomas must be considered as one of the differential diagnosis when patients present with a pituitary apoplexy...
  98. ncbi [Pulmonary and renal tuberculosis with cerebral tuberculoma mimicking metastatic lung cancer]
    S Lachkar
    Service de Pneumologie, CHU Charles Nicolle, Rouen, France
    Rev Mal Respir 25:97-9. 2008
  99. ncbi Tuberculoma of the cavernous sinus
    H Al Soub
    Department of Medicine, Hamad Medical Corporation, Doha, Qatar
    Scand J Infect Dis 33:868-70. 2001
    ..Treatment is primarily medical, with antituberculous drugs, and the outcome is good. Surgery has a limited role in the management of this condition, mainly for establishing the diagnosis...
  100. ncbi [Multiple intracranial tuberculomas in infancy]
    M Serrano
    , Esplugues de Llobregat, 08950,
    Rev Neurol 33:44-6. 2001
    ..This usually occurs within the first three months, and although the mechanism is unknown, it is believed to be due to the accumulation of lymphocytes and macrophages at preexisting microscopic foci when treatment is started...
  101. ncbi Possible role of adjunctive thalidomide therapy in the resolution of a massive intracranial tuberculous abscess
    J F Schoeman
    Department of Paediatrics and Child Health, Tygerberg Hospital and University of Stellenbosch, Cape Town, South Africa
    Childs Nerv Syst 17:370-2. 2001
    ..The remaining CT lesion had the appearance of a small granuloma. Both the clinical and the radiological response was maintained after 1 year of antituberculosis treatment...