impetigo

Summary

Summary: A common superficial bacterial infection caused by STAPHYLOCOCCUS AUREUS or group A beta-hemolytic streptococci. Characteristics include pustular lesions that rupture and discharge a thin, amber-colored fluid that dries and forms a crust. This condition is commonly located on the face, especially about the mouth and nose.

Top Publications

  1. ncbi Current options for the treatment of impetigo in children
    Michael J Sladden
    Department of Dermatology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
    Expert Opin Pharmacother 6:2245-56. 2005
  2. ncbi Prevalence of Staphylococcus aureus toxins and nasal carriage in furuncles and impetigo
    F Durupt
    INSERM, U851, 69008 Lyon, France Université Lyon 1, Centre National de Référence des Staphylocoques, Faculte Laennec, 69008 Lyon, France
    Br J Dermatol 157:1161-7. 2007
  3. ncbi Are lifetime prevalence of impetigo, molluscum and herpes infection really increased in children having atopic dermatitis?
    Sayaka Hayashida
    Department of Dermatology, Kyushu University, Higashiku, Fukuoka, Japan
    J Dermatol Sci 60:173-8. 2010
  4. ncbi Bacterial resistance and impetigo treatment trends: a review
    Scott Bangert
    Dermatology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    Pediatr Dermatol 29:243-8. 2012
  5. pmc High burden of impetigo and scabies in a tropical country
    Andrew C Steer
    Centre for International Child Health, University of Melbourne, Melbourne, Australia
    PLoS Negl Trop Dis 3:e467. 2009
  6. ncbi Interventions for impetigo
    Sander Koning
    Department of General Practice, ErasmusMedical Center, Rotterdam, Netherlands
    Cochrane Database Syst Rev 1:CD003261. 2012
  7. pmc Staphylococcus aureus isolated in cases of impetigo produces both epidermolysin A or B and LukE-LukD in 78% of 131 retrospective and prospective cases
    A Gravet
    , F-67000 Strasbourg, France
    J Clin Microbiol 39:4349-56. 2001
  8. ncbi Impetigo: incidence and treatment in Dutch general practice in 1987 and 2001--results from two national surveys
    S Koning
    Department of Paediatrics, Erasmus MC, University Medical Centre Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Br J Dermatol 154:239-43. 2006
  9. ncbi Impetigo: an update
    Justin Brown
    Dermatology, New Jersey Medical School, Newark, New Jersey 07103 2714, USA
    Int J Dermatol 42:251-5. 2003
  10. ncbi Retapamulin: a review of its use in the management of impetigo and other uncomplicated superficial skin infections
    Lily P H Yang
    Wolters Kluwer Health Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs 68:855-73. 2008

Detail Information

Publications198 found, 100 shown here

  1. ncbi Current options for the treatment of impetigo in children
    Michael J Sladden
    Department of Dermatology, Leicester Royal Infirmary, Leicester, LE1 5WW, UK
    Expert Opin Pharmacother 6:2245-56. 2005
    b>Impetigo contagiosa is a common, superficial, bacterial infection of the skin characterised by an inflamed and infected epidermis caused by Staphylococcus aureus, Streptococcus pyogenes or both...
  2. ncbi Prevalence of Staphylococcus aureus toxins and nasal carriage in furuncles and impetigo
    F Durupt
    INSERM, U851, 69008 Lyon, France Université Lyon 1, Centre National de Référence des Staphylocoques, Faculte Laennec, 69008 Lyon, France
    Br J Dermatol 157:1161-7. 2007
    ..The precise role of Staphylococcus aureus toxins and nasal carriage in common skin infections remains unclear...
  3. ncbi Are lifetime prevalence of impetigo, molluscum and herpes infection really increased in children having atopic dermatitis?
    Sayaka Hayashida
    Department of Dermatology, Kyushu University, Higashiku, Fukuoka, Japan
    J Dermatol Sci 60:173-8. 2010
    Cutaneous infections such as impetigo contagiosum (IC), molluscum contagiosum (MC) and herpes virus infection (HI) appear to be associated with atopic dermatitis (AD), but there are no reports of concrete epidemiological evidence.
  4. ncbi Bacterial resistance and impetigo treatment trends: a review
    Scott Bangert
    Dermatology, The University of Texas Health Science Center at Houston, Houston, TX 77030, USA
    Pediatr Dermatol 29:243-8. 2012
    b>Impetigo is a common cutaneous infection that is especially prevalent in children. The prevalence of colonization and infection with resistant strains is continually increasing, forcing clinicians to reevaluate treatment strategies...
  5. pmc High burden of impetigo and scabies in a tropical country
    Andrew C Steer
    Centre for International Child Health, University of Melbourne, Melbourne, Australia
    PLoS Negl Trop Dis 3:e467. 2009
    b>Impetigo and scabies are endemic diseases in many tropical countries; however the epidemiology of these diseases is poorly understood in many areas, particularly in the Pacific.
  6. ncbi Interventions for impetigo
    Sander Koning
    Department of General Practice, ErasmusMedical Center, Rotterdam, Netherlands
    Cochrane Database Syst Rev 1:CD003261. 2012
    b>Impetigo is a common, superficial bacterial skin infection, which is most frequently encountered in children. There is no generally agreed standard therapy, and guidelines for treatment differ widely...
  7. pmc Staphylococcus aureus isolated in cases of impetigo produces both epidermolysin A or B and LukE-LukD in 78% of 131 retrospective and prospective cases
    A Gravet
    , F-67000 Strasbourg, France
    J Clin Microbiol 39:4349-56. 2001
    Clinical symptoms of impetigo and staphylococcal scalded skin syndrome may not only be expressed as the splitting of cell layers within the epidermis but are often accompanied by some localized inflammation...
  8. ncbi Impetigo: incidence and treatment in Dutch general practice in 1987 and 2001--results from two national surveys
    S Koning
    Department of Paediatrics, Erasmus MC, University Medical Centre Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    Br J Dermatol 154:239-43. 2006
    b>Impetigo is a common skin infection in children. The epidemiology is relatively unknown, and the choice of treatment is subject to debate.
  9. ncbi Impetigo: an update
    Justin Brown
    Dermatology, New Jersey Medical School, Newark, New Jersey 07103 2714, USA
    Int J Dermatol 42:251-5. 2003
  10. ncbi Retapamulin: a review of its use in the management of impetigo and other uncomplicated superficial skin infections
    Lily P H Yang
    Wolters Kluwer Health Adis, 41 Centorian Drive, Private Bag 65901, Mairangi Bay, North Shore 0754, Auckland, New Zealand
    Drugs 68:855-73. 2008
    ..In the EU, retapamulin is indicated for use in patients with impetigo or with infected small lacerations, abrasions or sutured wounds (without abscesses); in the US, it is indicated ..
  11. ncbi Microbiology of nonbullous impetigo
    I Brook
    Department of Pediatrics, Bethesda Naval Hospital, Maryland, USA
    Pediatr Dermatol 14:192-5. 1997
    Our objective was to establish the aerobic and anaerobic microbiology of nonbullous impetigo (NI) in children. We used a retrospective review of clinical microbiology laboratory and patients' records...
  12. ncbi Impetigo: a reassessment of etiology and therapy
    L L Barton
    Department of Pediatrics/Adolescent Medicine, St. Louis University School of Medicine, Missouri
    Pediatr Dermatol 4:185-8. 1987
    Traditional concepts regarding the bacteriology and therapy of nonbullous impetigo have been reexamined...
  13. ncbi Anaphylaxis to polyvinylpyrrolidone in povidone-iodine for impetigo contagiosum in a boy with atopic dermatitis
    Koichi Yoshida
    Department of Pediatrics, Nara Medical University School of Medicine, Kashihara, Japan
    Int Arch Allergy Immunol 146:169-73. 2008
    ..Polyvinylpyrrolidone (PVP) is thought to play a role in the underlying mechanism. We examined the usefulness of the histamine release test (HRT) for definite diagnosis of PVP allergy...
  14. ncbi Roles of the plasminogen activator streptokinase and the plasminogen-associated M protein in an experimental model for streptococcal impetigo
    Mikael D Svensson
    Department of Laboratory Medicine, Lund University, Lund, Sweden
    Microbiology 148:3933-45. 2002
    ..A streptococci (GAS) takes place at either the throat or skin of the human host, often leading to pharyngitis or impetigo, respectively. Many GAS strains differ in their preference for throat and skin tissue sites...
  15. ncbi Spread of the epidemic European fusidic acid-resistant impetigo clone (EEFIC) in general practice patients in the south of The Netherlands
    M I A Rijnders
    Department of Medical Microbiology, Care and Public Health Research Institute Caphri, Maastricht University Medical Centre, Maastricht, The Netherlands
    J Antimicrob Chemother 67:1176-80. 2012
    ..We evaluated the susceptibility to fusidic acid, mupirocin and retapamulin of Staphylococcus aureus isolated from nasal and wound swabs...
  16. ncbi Outbreak of staphylococcal bullous impetigo in a maternity ward linked to an asymptomatic healthcare worker
    P Occelli
    Centre de Coordination de la Lutte contre les Infections Nosocomiales du Sud Ouest, CHU, Bordeaux Cedex, France
    J Hosp Infect 67:264-70. 2007
    An outbreak of staphylococcal bullous impetigo occurred over a period of five months in a maternity ward involving seven infected and two colonised neonates...
  17. ncbi Effect of antenatal zinc supplementation on impetigo in infants in Bangladesh
    Gary L Darmstadt
    International Center for Advancing Neonatal Health, Department of International Health, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, MD, USA
    Pediatr Infect Dis J 31:407-9. 2012
    ..6% had at least 1 episode of impetigo compared with 19.6% of the infants of mothers in the placebo group (P = 0.01)...
  18. ncbi Spotlight on retapamulin in impetigo and other uncomplicated superficial skin infections
    Lily P H Yang
    Wolters Kluwer Health, Auckland, New Zealand
    Am J Clin Dermatol 9:411-3. 2008
    ..In the EU, retapamulin is indicated for use in patients with impetigo or with infected small lacerations, abrasions, or sutured wounds (without abscesses); in the US, it is indicated ..
  19. ncbi Recurrent impetigo herpetiformis successfully treated with methotrexate: a case report
    Suchaya Luewan
    Maternal Fetal Medicine Unit, Department of Obstetrics and Gynecology, Chiang Mai University, Chiang Mai, Thailand
    J Obstet Gynaecol Res 37:661-3. 2011
    b>Impetigo herpetiformis is a rare disease and its occurrence is specific for pregnancy. The lesions are characterized by sterile, pustular eruptions...
  20. ncbi Impetigo in a population over 8.5 years: incidence, fusidic acid resistance and molecular characteristics
    Sverre Rørtveit
    Municipal Health Services of Austevoll, Bekkjarvik, Norway
    J Antimicrob Chemother 66:1360-4. 2011
    From around year 2000, impetigo caused by fusidic acid-resistant Staphylococcus aureus was observed in countries of Northern Europe...
  21. ncbi [Recurrent Impetigo Herpetiformis: successfully managed with ciclosporine. Report of one case]
    Enrique Valdés
    Departamento de Obstetricia y Ginecologia, Hospital Clinico, Universidad de Chile
    Rev Med Chil 133:1070-4. 2005
    b>Impetigo Herpetiformis is a high-risk gestational skin disease that represents a risk for both the mother and offspring. Its management is based on multisystemic support and maternal steroid therapy...
  22. ncbi Seasonal occurrence of impetigo: a retrospective 8-year review (1996-2003)
    A Loffeld
    Department of Dermatology, Birmingham Children s Hospital, Birmingha, UK
    Clin Exp Dermatol 30:512-4. 2005
    b>Impetigo, a common skin infection, has shown seasonal variation in African, Australian and Indian studies. We investigated seasonal variation of impetigo in a UK paediatric population...
  23. ncbi Successful treatment of impetigo herpetiformis with oral cyclosporine during pregnancy
    Naoko Imai
    Arch Dermatol 138:128-9. 2002
  24. ncbi Pemphigus, bullous impetigo, and the staphylococcal scalded-skin syndrome
    John R Stanley
    Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    N Engl J Med 355:1800-10. 2006
  25. ncbi The effect of antibacterial soap on impetigo incidence, Karachi, Pakistan
    Stephen Luby
    National Center of Infectious Disease, Centers for Disease Control, Atlanta, Georgia 30333, USA
    Am J Trop Med Hyg 67:430-5. 2002
    ..2% triclocarban would be effective in reducing the incidence of impetigo. We randomized 162 households in a low-income neighborhood of Karachi, Pakistan, to receive a regular supply of 1...
  26. pmc Molecular mechanisms of blister formation in bullous impetigo and staphylococcal scalded skin syndrome
    Yasushi Hanakawa
    Department of Dermatology, University of Pennsylvania School of Medicine, 415 Curie Boulevard, Philadelphia, PA 19104, USA
    J Clin Invest 110:53-60. 2002
    Bullous impetigo due to Staphylococcus aureus is one of the most common bacterial infections of man, and its generalized form, staphylococcal scalded skin syndrome (SSSS), is a frequent manifestation of staphylococcal epidemics in ..
  27. ncbi Molecular epidemiology and antimicrobial susceptibilities of 273 exfoliative toxin-encoding-gene-positive Staphylococcus aureus isolates from patients with impetigo in Japan
    Hidemasa Nakaminami
    Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    J Med Microbiol 57:1251-8. 2008
    ..273 Staphylococcus aureus isolates positive for the exfoliative toxin-encoding gene obtained from patients with impetigo in Japan in 2006 were studied. The mecA gene was detected in 74 meticillin-resistant S...
  28. pmc Bullous impetigo in children infected with methicillin-resistant Staphylococcus aureus alone or in combination with methicillin-susceptible S. aureus: analysis of genetic characteristics, including assessment of exfoliative toxin gene carriage
    Da Shi
    Division of Bacteriology, Department of Infectious Disease Control and International Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan
    J Clin Microbiol 49:1972-4. 2011
    Among bullous impetigo isolates, exfoliative toxin (ET) gene carriage was found in 61.5% of methicillin-resistant Staphylococcus aureus (MRSA) isolates versus 90.6% of methicillin-susceptible S. aureus (MSSA) isolates...
  29. ncbi The association between impetigo, insect bites and air temperature: a retrospective 5-year study (1999-2003) using morbidity data collected from a sentinel general practice network database
    Alex J Elliot
    Birmingham Research Unit of the Royal College of General Practitioners, Harborne, Birmingham, UK
    Fam Pract 23:490-6. 2006
    b>Impetigo is one of the commonest childhood skin infections. Insect bites are commonly implicated in the development of impetigo...
  30. ncbi Antimicrobial resistance of Staphylococcus aureus isolated from impetigo patients between 1994 and 2000
    Setsuko Nishijim
    Department of Dermatology and Bacterial Medicine Laboratories, Kansa Medical University, Kori Hospital, Neyagawa, Osaka, Japan
    Int J Dermatol 42:23-5. 2003
    The incidence of strains of Staphylococcus aureus resistant to the antimicrobial agents used in treating impetigo has been increasing.
  31. pmc Fusidic acid cream in the treatment of impetigo in general practice: double blind randomised placebo controlled trial
    Sander Koning
    Department of General Practice, University Hospital Rotterdam, Room Ff325, PO Box 1738, Erasmus University, 3000 DR Rotterdam, Netherlands
    BMJ 324:203-6. 2002
    To test the hypothesis that fusidic acid would not increase the treatment effect of disinfecting with povidone-iodine alone in children with impetigo.
  32. pmc Characterization of the epidemic European fusidic acid-resistant impetigo clone of Staphylococcus aureus
    A J O'Neill
    Antimicrobial Research Centre and Institute of Molecular and Cellular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom
    J Clin Microbiol 45:1505-10. 2007
    Resistance to the antibiotic fusidic acid in European strains of Staphylococcus aureus causing impetigo has increased in recent years...
  33. ncbi Bullous impetigo of the face after epilation by threading
    Michelle Weisfelner Bloom
    Arch Dermatol 141:1174-5. 2005
  34. ncbi Desmosomes and disease: pemphigus and bullous impetigo
    Aimee S Payne
    Department of Dermatology, University of Pennsylvania, Philadelphia, 415 Curie Boulevard, 211 Clinical Research Building, Pennsylvania, 19104 USA
    Curr Opin Cell Biol 16:536-43. 2004
    ..pathophysiologic targets of autoimmune or toxin-mediated disruption in the human diseases pemphigus and bullous impetigo (including its generalized form, called staphylococcal scalded skin syndrome)...
  35. pmc Genetically diverse group A streptococci from children in far-western Nepal share high genetic relatedness with isolates from other countries
    Varja Sakota
    Division of Bacterial and Myotic Diseases, Respiratory Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Clin Microbiol 44:2160-6. 2006
    ..Similarly, since most (40/51) strain types were highly related to strains found elsewhere, it is likely that a major fraction of the existing GAS clonal complexes have been discovered...
  36. pmc Differences between Belgian and Brazilian group A Streptococcus epidemiologic landscape
    Pierre Robert Smeesters
    Infectious Diseases Department, Hopital Universitaire des Enfants Reine Fabiola, Universite Libre de Bruxelles, Brussels, Belgium
    PLoS ONE 1:e10. 2006
    ..Group A Streptococcus (GAS) clinical and molecular epidemiology varies with location and time. These differences are not or are poorly understood...
  37. ncbi Antimicrobial susceptibility of Staphylococcus aureus isolated from children with impetigo in China from 2003 to 2007 shows community-associated methicillin-resistant Staphylococcus aureus to be uncommon and heterogeneous
    Y Liu
    Department of Dermatology, Beijing Children s Hospital, Capital Medical University, Beijing, China
    Br J Dermatol 161:1347-50. 2009
    The number of patients with impetigo caused by community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been increasing.
  38. pmc Antimicrobial agent of susceptibilities and antiseptic resistance gene distribution among methicillin-resistant Staphylococcus aureus isolates from patients with impetigo and staphylococcal scalded skin syndrome
    Norihisa Noguchi
    Department of Microbiology, School of Pharmacy, Tokyo University of Pharmacy and Life Science, 1432 1 Horinouchi, Hachioji, Tokyo 192 0392, Japan
    J Clin Microbiol 44:2119-25. 2006
    ..The data of MRSA strains that are causative agents of impetigo and staphylococcal scalded skin syndrome (SSSS) were compared with those of MRSA strains isolated from patients ..
  39. ncbi Treatment of bullous impetigo and the staphylococcal scalded skin syndrome in infants
    Graham A Johnston
    Department of Dermatology, Leicester Royal Infirmary, LE1 5WW Leicester, UK
    Expert Rev Anti Infect Ther 2:439-46. 2004
    b>Impetigo is a common, superficial, bacterial infection of the skin characterized by an inflamed and infected epidermis...
  40. pmc Severity of nonbullous Staphylococcus aureus impetigo in children is associated with strains harboring genetic markers for exfoliative toxin B, Panton-Valentine leukocidin, and the multidrug resistance plasmid pSK41
    Sander Koning
    Department of General Practice, Erasmus MC University Medical Center Rotterdam, 3015 GD Rotterdam, The Netherlands
    J Clin Microbiol 41:3017-21. 2003
    Nonbullous impetigo is a common skin infection in children and is frequently caused by Staphylococcus aureus. Staphylococcal toxins and especially exfoliative toxin A are known mediators of bullous impetigo in children...
  41. ncbi Confocal laser scanning microscopic observation of glycocalyx production by Staphylococcus aureus in skin lesions of bullous impetigo, atopic dermatitis and pemphigus foliaceus
    H Akiyama
    Department of Dermatology, Okayama University Graduate School of Medicine and Dentistry, Shikata cho 2 5 1, Okayama 700 8558, Japan
    Br J Dermatol 148:526-32. 2003
    ..Glycocalyx collapses during dehydration to produce electron-dense accretions. Confocal laser scanning microscopy (CLSM) may be used to visualize fully hydrated microbial biofilms...
  42. ncbi Tinea faciei in an infant caused by Microsporum gypseum simulating a dry impetigo
    Paulo Ricardo Criado
    Dermatology Unit, Hospital do Servidor Publico Estadual de Sao Paulo, Brazil
    Pediatr Dermatol 22:536-8. 2005
    ..The initial examination led us to the clinical diagnosis of impetigo. The mycologic studies found an uncommon dermatophyte agent, Microsporum gypseum...
  43. pmc A systematic review and meta-analysis of treatments for impetigo
    Ajay George
    Centre for Primary and Community Care, University of Sunderland, Benedict Building, St George s Way, Sunderland SR2 7BW
    Br J Gen Pract 53:480-7. 2003
    b>Impetigo is a common clinical problem seen in general practice. Uncertainty exists as to the most effective treatment, or indeed if treatment is necessary.
  44. ncbi A fusidic acid-resistant clone of Staphylococcus aureus associated with impetigo bullosa is spreading in Norway
    Yngvar Tveten
    Telemark Biomedical Centre, A S Telelab, Department of Medical Microbiology, Strømdaljordet 4, PO Box 1868, N 3703 Skien, Norway
    J Antimicrob Chemother 50:873-6. 2002
    ..To investigate the possibility that the increased prevalence of fusidic acid-resistant Staphylococcus aureus in Norway is caused by clonal spread...
  45. ncbi Determinants of regional differences in the incidence of impetigo
    R Ghotb Razmjou
    Department of General Practice, Erasmus MC University Medical Center, room Ff305, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Environ Res 109:590-3. 2009
    b>Impetigo is a common contagious skin infection, mostly seen in children and caused by Staphylococcus aureus and/or group A B-hemolytic Streptococcus...
  46. ncbi Clonal association of Staphylococcus aureus causing bullous impetigo and the emergence of new methicillin-resistant clonal groups in Kansai district in Japan
    Takayuki Yamaguchi
    Department of Bacteriology, Hiroshima University Graduate School of Biomedical Sciences, Hiroshima, Japan
    J Infect Dis 185:1511-6. 2002
    ..performed to reveal the clonal association of Staphylococcus aureus strains isolated from patients with bullous impetigo. Pulsed-field gel electrophoresis with cluster analysis, genetic and phenotypic characterizations, and ..
  47. ncbi Recurrent impetigo herpetiformis in a pregnant adolescent: case report
    H Guler Sahin
    Department of Obstetrics and Gynecology, University of Yuzuncu Yil, Medical Faculty, Van, Turkey
    Eur J Obstet Gynecol Reprod Biol 101:201-3. 2002
    b>Impetigo Herpetiformis is a rare pustular dermatosis that typically occurs in pregnant women with unknown etiology...
  48. ncbi Contrasting molecular epidemiology of group A streptococci causing tropical and nontropical infections of the skin and throat
    D E Bessen
    Yale University School of Medicine, Dept of Epidemiology and Public Health, New Haven, CT 06520
    J Infect Dis 182:1109-16. 2000
    Disease caused by group A streptococci (GAS) in tropical regions often takes the form of impetigo, whereas pharyngitis tends to predominate in temperate zones...
  49. ncbi Epidemiology of group A streptococcal pharyngitis & impetigo: a cross-sectional & follow up study in a rural community of northern India
    R Kumar
    School of Public Health, Postgraduate Institute of Medical Education and Research, Chandigarh 160 012, India
    Indian J Med Res 130:765-71. 2009
    ..Hence, disease burden due to GAS in 5-15 yr old school children in northern India was studied and emm typing of GAS isolates was carried out to help in designing prevention strategies...
  50. ncbi Trimethopim-sulfamethoxazole compared with benzathine penicillin for treatment of impetigo in Aboriginal children: a pilot randomised controlled trial
    Steven Y C Tong
    Menzies School of Health Research, Charles Darwin University, Darwin, Australia
    J Paediatr Child Health 46:131-3. 2010
    ..randomized controlled trial comparing trimethoprim-sulfamethoxazole to benzathine penicillin for treatment of impetigo in Aboriginal children...
  51. pmc NVC-422 topical gel for the treatment of impetigo
    Susan M Iovino
    NovaBay Pharmaceuticals Inc, Emeryville, CA 94605, USA
    Int J Clin Exp Pathol 4:587-95. 2011
    b>Impetigo is a highly contagious bacterial skin infection affecting children worldwide that is caused by the Gram-positive bacteria Staphylococcus aureus, Streptococcus pyogenes, or both...
  52. ncbi Dissemination of multiple MRSA clones among community-associated methicillin-resistant Staphylococcus aureus infections from Japanese children with impetigo
    Ken Hisata
    Department of Infection Control Science, School of Medicine, Juntendo University, Tokyo, Japan
    J Infect Chemother 17:609-21. 2011
    ..In 3 months we have characterized 17 MRSA strains isolated from children with impetigo at a Japanese hospital...
  53. ncbi Efficacy and safety of retapamulin ointment as treatment of impetigo: randomized double-blind multicentre placebo-controlled trial
    S Koning
    Department of General Practice, Erasmus MC University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Br J Dermatol 158:1077-82. 2008
    b>Impetigo is a common skin infection, primarily caused by Staphylococcus aureus and mainly occurring in children. It is usually treated topically with antibiotics to achieve a quick cure and prevent spread of the infection...
  54. ncbi Third-trimester impetigo herpetiformis treated with cyclosporine
    Lori Brightman
    J Am Acad Dermatol 56:S62-4. 2007
  55. ncbi Topical retapamulin ointment, 1%, versus sodium fusidate ointment, 2%, for impetigo: a randomized, observer-blinded, noninferiority study
    Arnold P Oranje
    Department of Dermatology and Venereology Pediatric Dermatology, University Medical Center Sophia Children s Hospital, Rotterdam, The Netherlands
    Dermatology 215:331-40. 2007
    ..Retapamulin is a novel pleuromutilin antibacterial developed for topical use...
  56. ncbi Recurrent staphylococcal conjunctivitis associated with facial impetigo contagiosa
    Shane R Durkin
    Department of Ophthalmology and Visual Science, Royal Adelaide Hospital, University of Adelaide, Adelaide, SA 5000, Australia
    Am J Ophthalmol 141:189-90. 2006
    To report the uncommon occurrence of impetigo contagiosa in the setting of recurrent staphylococcal conjunctivitis.
  57. ncbi Effect of handwashing on child health: a randomised controlled trial
    Stephen P Luby
    Division of Bacterial and Mycotic Diseases, National Centers for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Lancet 366:225-33. 2005
    ..We undertook a randomised controlled trial to assess the effect of handwashing promotion with soap on the incidence of acute respiratory infection, impetigo, and diarrhoea.
  58. pmc A Panton-Valentine leucocidin (PVL)-positive community-acquired methicillin-resistant Staphylococcus aureus (MRSA) strain, another such strain carrying a multiple-drug resistance plasmid, and other more-typical PVL-negative MRSA strains found in Japan
    Yoko Takizawa
    Department of Infectious Disease Control and International Medicine, Division of Bacteriology, Niigata University Graduate School of Medical and Dental Sciences, 757 Ichibanchou, Asahimachidori, Niigata, Japan
    J Clin Microbiol 43:3356-63. 2005
    Community-acquired methicillin-resistant Staphylococcus aureus (CA-MRSA) was collected from children with bullous impetigo in 2003 and 2004. One strain collected in 2003 was Panton-Valentine leucocidin (PVL) positive...
  59. ncbi Impetigo: aetiology, complications and treatment options
    Philip Watkins
    Merton Primary Care Tust, Mitcham, Surrey
    Nurs Stand 19:50-4. 2005
    This article describes impetigo, and outlines differential diagnoses, likely complications associated with impetigo and signs and symptoms...
  60. pmc Clinical manifestations of staphylococcal scalded-skin syndrome depend on serotypes of exfoliative toxins
    Osamu Yamasaki
    Centre National de Référencedes Staphylocoques, INSERM E0230, IFR62 Laennec, 7 rue Guillaume Paradin, 69372 Lyon Cedex 08, France
    J Clin Microbiol 43:1890-3. 2005
    ..in Staphylococcus aureus strains isolated from 103 patients with generalized SSSS and 95 patients with bullous impetigo. The eta gene and the etb gene were detected in, respectively, 31 (30%) and 20 (19%) episodes of generalized SSSS ..
  61. ncbi Generalized bullous impetigo in a neonate
    Kamaldeep Sandhu
    Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    Pediatr Dermatol 21:667-9. 2004
    Generalized bullous impetigo is uncommon in healthy and term neonates. It must be differentiated from staphylococcal scalded skin syndrome and other commonly encountered vesiculopustular lesions...
  62. ncbi Evaluation of simplified DNA extraction methods for emm typing of group A streptococci
    J J M Jose
    Department of Clinical Microbiology, Christian Medical College, Vellore 632 004, Tamil Nadu, India
    Indian J Med Microbiol 24:127-30. 2006
    ..the standard CDC cell lysate method for emm typing of 50 GAS strains isolated from children with pharyngitis and impetigo. For this, GAS colonies were transferred into two sets of PCR tubes...
  63. ncbi Impetigo in epidemic and nonepidemic phases: an incidence study over 4(1/2) years in a general population
    S Rørtveit
    Municipal Health Services of Austevoll Kommune, 5399 Bekkjarvik, Norway
    Br J Dermatol 157:100-5. 2007
    Little is known about incidence and natural variation of impetigo in general populations.
  64. ncbi Bullous impetigo: a rare presentation in fulminant streptococcal toxic shock syndrome
    Jainn Jim Lin
    Division of Pediatric Critical Care and Emergency Medicine, Chang Gung Children s Hospital and Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Pediatr Emerg Care 23:318-20. 2007
    ..However, bullous impetigo is invariably considered to be a staphylococcal disease...
  65. ncbi Management of common bacterial infections of the skin
    Philippe Bernard
    Department of Dermatology, Robert Debre Hospital, Reims, France
    Curr Opin Infect Dis 21:122-8. 2008
    Bacterial skin infections commonly encountered in the community include impetigo, folliculitis/furunculosis, simple abscesses, erysipelas and other nonnecrotizing cellulitis...
  66. ncbi [Handwashing and body hygiene: infections in childhood are significantly reduced]
    Hardy Thorsten Panknin
    Kinderkrankenschwester 26:514-5. 2007
  67. ncbi Impetigo in soldiers after hand-to-hand combat training
    Flavio Lejbkowicz
    Clinical Microbiology and Dermatology, Western Galilee Hospital, Naharyia, Israel
    Mil Med 170:972-4. 2005
    Bacterial skin infections are very common and trigger destruction of the skin integrity. Impetigo is a consequence of group A beta-hemolytic streptococcus or Staphylococcus aureus infection...
  68. ncbi Changing epidemiology of acute post-streptococcal glomerulonephritis in Northeast Florida: a comparative study
    Mohammad Ilyas
    Pediatric Nephrology, University of Florida Jacksonville, Jacksonville, FL, USA
    Pediatr Nephrol 23:1101-6. 2008
    ..Pharyngitis has replaced impetigo as the predominant cause of APSGN...
  69. ncbi Retapamulin: a semisynthetic pleuromutilin compound for topical treatment of skin infections in adults and children
    Michael R Jacobs
    Case Western Reserve University and University Hospitals Case Medical Center, Department of Pathology, 11100 Euclid Avenue, Cleveland, OH 44106, USA
    Future Microbiol 2:591-600. 2007
    ..A 1% ointment formulation has been developed for clinical use, and a placebo-controlled trial of impetigo in 210 patients produced significantly higher rates of clinical and microbiological success compared with placebo ..
  70. ncbi [Impetigo]
    J Mazereeuw-Hautier
    Service de Dermatologie, Hopital Rangueil, 1, avenue Jean Poulhes, TSA 50032, 31059 Toulouse cedex 09
    Ann Dermatol Venereol 133:194-207. 2006
  71. ncbi Treatment of uncomplicated skin and skin infections in the pediatric and adolescent patient populations
    Lawrence A Schachner
    University of Miami School of Medicine, FL 33101 6250, USA
    J Drugs Dermatol 4:s30-3. 2005
    ..Studies conducted in Miami show that during the early 1980s, the predominant pathogen associated with impetigo in pediatric patients shifted from Streptococcus pyogenes to Staphylococcus aureus...
  72. ncbi Novel antibacterial activity of monolaurin compared with conventional antibiotics against organisms from skin infections: an in vitro study
    Beatriz G Carpo
    Department of Dermatology, Makati Medical Center, Makati City, Philippines
    J Drugs Dermatol 6:991-8. 2007
    ....
  73. ncbi Topical antibiotic treatment of impetigo with tetracycline
    Shuichi Kuniyuki
    Department of Dermatology, Osaka City General Hospital, Osaka, Japan
    J Dermatol 32:788-92. 2005
    ..2-13 years with bullous and eroded lesions, from which Staphylococcus aureus was isolated, were diagnosed with impetigo and entered into a randomized, open-labeled trial of topical oxytetracycline hydrochloride (tetracycline) ..
  74. ncbi [Contagious impetigo--an interdisciplinary clinical picture]
    J Dissemond
    Klinik und Poliklinik fur Dermatologie, Venerologie und Allergologie, Universitatsklinikum Essen
    Dtsch Med Wochenschr 127:1648-50. 2002
  75. ncbi [Impetigo bullosa]
    Yngvar Tveten
    Tidsskr Nor Laegeforen 123:3089; author reply 3089. 2003
  76. ncbi Impetigo neonatorum associated with late onset group B streptococcal meningitis
    Ananya Guha
    Royal Liverpool Childrens NHS Trust, Alder Hey, Eaton Road, Liverpool L12 2AP, UK
    J Infect 47:185-7. 2003
    We present a case of nonbullous impetigo neonatorum associated with late onset group B streptococcal meningitis in a 12-day-old infant. Both skin lesions and meningitis resolved with antibiotic therapy...
  77. ncbi Staphylococcal epidermolysins
    Gilles Prevost
    Laboratory for Pathophysiology of Emergent and Nosocomial Bacteria, Bacteriology Institute of the Faculty of Medicine, Strasbourg, France
    Curr Opin Infect Dis 16:71-6. 2003
    Staphylococcal epidermolysins are the major causative toxins of bullous impetigo and staphylococcal scalded skin syndrome. This disease is characterized by the splitting of the epidermis between two cell layers resulting in exfoliation...
  78. ncbi An inhibitor of Staphylococcus aureus exfoliative toxin
    A A Al-Sulami
    Department of Biology, College of Education, University of Basra, Basra, Iraq
    East Mediterr Health J 7:121-7. 2001
    ..Furthermore it appeared to contain a substance that neutralized the action of exfoliative toxin. This suggests the possibility of a treatment for staphylococcal scalded skin syndrome and bullous impetigo.
  79. ncbi Clonal spread among Swedish children of a Staphylococcus aureus strain resistant to fusidic acid
    A Osterlund
    Department of Clinical Microbiology, Central Hospital, Vaxjo, Sweden
    Scand J Infect Dis 34:729-34. 2002
    ..Data from 1 of the laboratories demonstrated a close connection between this clone and impetigo. Sales statistics showed a pronounced increase in the use of fusidic acid ointments in the 0-12 y age group from ..
  80. pmc Fusidic acid cream for impetigo. Fusidic acid should be used with restraint
    Erwin M Brown
    BMJ 324:1394. 2002
  81. ncbi Fusidic acid cream for impetigo. Judicious use is advisable
    Olajumoke Sule
    BMJ 324:1394. 2002
  82. ncbi Fusidic acid cream for impetigo. Emergence of resistance to fusidic acid limits its use
    Vivienne C Weston
    BMJ 324:1394. 2002
  83. ncbi Fusidic acid cream for impetigo. Problem may be clinically important
    Bethan Stoddart
    BMJ 324:1394. 2002
  84. ncbi Fusidic acid cream for impetigo. Resistance trends must be monitored
    Paul Zadik
    BMJ 324:1394. 2002
  85. ncbi Mupirocin vs terbinafine in impetigo
    Ergin Ciftci
    Pediatric Clinic of Elmadag State Hospital, Ankara, Turkey
    Indian J Pediatr 69:679-82. 2002
    ..To compare the efficacy and safety of terbinafine with those of mupirocin, which has already proven antibacterial action, in the treatment of impetigo.
  86. ncbi Fusidic acid cream for impetigo. Findings cannot be extrapolated
    Susannah E Owen
    BMJ 324:1394. 2002
  87. ncbi Systemic or topical treatment for impetigo?
    Hannah Gunn
    Glasgow University, Scotland
    Aust Fam Physician 32:1022. 2003
  88. ncbi Prevalence of staphylococcal zoonosis in pyogenic skin infections
    P N Rao
    Institute of Preventive Medicine, Public Health Laboratories and Food Health Authority, Hyderabad, India
    Zentralbl Bakteriol Mikrobiol Hyg A 265:218-26. 1987
    ..aureus of animal host origin. Dogs, cattle and poultry were found to be the most important reservoirs transmitting S. aureus to humans, with folliculitis, furunculosis, impetigo as the frequent clinical manifestations.
  89. ncbi The frequency of erythromycin-resistant Staphylococcus aureus in impetiginized dermatoses
    M L Misko
    Department of Dermatology, University of Texas Medical Branch, Galveston 77555-0783, USA
    Pediatr Dermatol 12:12-5. 1995
    ..We conclude that S. aureus is the most common causative organism in secondary skin infections and impetigo in our patient population...
  90. ncbi Impetigo: an overview
    G L Darmstadt
    Department of Dermatology, Stanford University School of Medicine, California, Palo Alto 94304
    Pediatr Dermatol 11:293-303. 1994
    This article reviews in detail the pathogenesis, clinical characteristics and management of impetigo in children. Impetigo is the most common bacterial skin infection of children...
  91. pmc A fusidic acid-resistant epidemic strain of Staphylococcus aureus carries the fusB determinant, whereas fusA mutations are prevalent in other resistant isolates
    Alexander J O'Neill
    Antimicrobial Research Centre and School of Biochemistry and Microbiology, University of Leeds, Leeds LS2 9JT, UK
    Antimicrob Agents Chemother 48:3594-7. 2004
    Fusidic acid-resistant epidemic Staphylococcus aureus strains causing impetigo bullosa have been reported in Scandinavia. We show that these strains form part of a European epidemic clonotype that carries the fusB determinant...
  92. ncbi [An epidemic of bullous impetigo in the municipality of Austevoll in the year 2002]
    Sverre Rørtveit
    Kommunelegekontoret, 5399 Bekkjarvik
    Tidsskr Nor Laegeforen 123:2557-60. 2003
    Rising numbers of bullous impetigo caused by Staphylococcus aureus resistant to fucidic acid have been seen in Norway over the last few years.
  93. ncbi Impetigo contagiosa III. Comparative efficacy of oral erythromycin and topical mupirocin
    L L Barton
    St. Louis University School of Medicine, Department of Pediatrics/Adolescent Medicine, Missouri
    Pediatr Dermatol 6:134-8. 1989
    Ninety-seven patients with impetigo were prospectively enrolled in a study to determine the comparative efficacy of systemic and topical antibiotic therapy...
  94. ncbi [Antibacterial sensitivity, phage group and coagulase type of Staphylococcus aureus isolated from bullous impetigo]
    K Kagami
    Department of Dermatology, Kyoto First Red Cross Hospital
    Kansenshogaku Zasshi 71:1108-12. 1997
    Bullous Impetigo caused mainly by S. aureus is seen in high incidence in children. Three decades ago CEMs were much more effective for bullous impetigo than today. Recently, the causative S...
  95. ncbi [Clinical aspects of streptococcal and staphylococcal toxinic diseases]
    D Floret
    Service d urgence et de réanimation pédiatriques, Hopital Edouard Herriot, Place d Arsonval, 69437 Lyon, France
    Arch Pediatr 8:762s-768s. 2001
    ..Severe extensive forms have been observed particularly in neonates (Ritter's disease). Bullous impetigo is also due to exfoliatin...
  96. ncbi Acute bacterial skin infections in pediatric medicine: current issues in presentation and treatment
    James Hedrick
    Physicians to Children and Adolescents, Bardstown, KY 40004, USA
    Paediatr Drugs 5:35-46. 2003
    Bacterial skin and skin structure infections commonly encountered in children include impetigo, folliculitis, furunculosis, carbuncles, wound infections, abscesses, cellulitis, erysipelas, scarlet fever, acute paronychia, and ..
  97. ncbi [Pharmacokinetic and clinical studies of cefteram pivoxil granule in the pediatric field]
    T Motohiro
    Department of Pediatrics, School of Medicine, Kurume University
    Jpn J Antibiot 42:2023-61. 1989
    ..12), acute bronchitis (3), pneumonia (11), pleurisy (1), scarlet fever (28), acute purulent otitis media (16), impetigo (13), abscess (2), purulent lymphadenitis (1) and urinary tract infection (33)...
  98. ncbi [Antibiotic susceptibility of Staphylococcus aureus strains responsible for community-acquired skin infections]
    P Bernard
    Service de Dermatologie, Hopital Robert Debre, CHU de Reims, avenue du Maréchal Koenig, 51092 Reims Cedex, France
    Ann Dermatol Venereol 135:13-9. 2008
    ..aureus responsible for cutaneous infections seen in general practice...
  99. ncbi Quality control in chronic wound management: the role of local povidone-iodine (Betadine) therapy
    Judit Daroczy
    Department of Dermatology and Lymphology, St Stephan Hospital, Budapest, Hungary
    Dermatology 212:82-7. 2006
    ..Stasis dermatitis related to chronic venous insufficiency accompanied by infected superficial ulcers must be differentiated from erysipelas, cellulitis and contact eczema...
  100. ncbi Dermatological findings in 3 generations of a family with a high prevalence of human T cell lymphotropic virus type 1 infection in Brazil
    Vandack Nobre
    Infectious Diseases Branch, Federal University of Minas Gerais, Minas Gerais, Brazil
    Clin Infect Dis 43:1257-63. 2006
    ..The aim of this study was to investigate dermatological findings presented by 30 members of a Brazilian family, half of whom are infected with HTLV-1 (as confirmed by enzyme-linked immunosorbent assay and Western blot)...
  101. pmc Autoimmune and infectious skin diseases that target desmogleins
    Masayuki Amagai
    Department of Dermatology, Keio University School of Medicine, Tokyo, Japan
    Proc Jpn Acad Ser B Phys Biol Sci 86:524-37. 2010
    ..also targeted by exfoliative toxin (ET) released by Staphylococcus aureus in the infectious skin diseases bullous impetigo and staphylococcal scalded skin syndrome (SSSS)...

Research Grants21

  1. Delineation of the molecular mechanisms underlying group A Streptococcus virulenc
    Paul Sumby; Fiscal Year: 2013
    ..human bacterial pathogen group A Streptococcus (GAS) causes a broad spectrum of diseases, including pharyngitis, impetigo, and necrotizing fasciitis...
  2. Metal-dependent phosphohydrolase activity of CvfA from Streptococcus pyogenes
    GABRIELA CITLALLI PEREZ-ALVARADO; Fiscal Year: 2012
    ..Group A Streptococcus (GAS) is associated with a broad range of human diseases including scarlet fever, impetigo, pharyngitis, necrotizing fasciitis, streptococcal toxic shock syndrome and the post- streptococcal sequelae of ..
  3. Host defense against Staphylococcus aureus skin infections
    Lloyd S Miller; Fiscal Year: 2010
    ..S. aureus is responsible for the vast majority of skin and soft tissue infections such as impetigo, folliculitis, and cellulitis. In addition, S...
  4. Tissue-Specific Infection by Group A Streptococci
    DEBRA BESSEN; Fiscal Year: 2009
    ..and involve one of two tissues - the epithelial surface of the throat or skin - giving rise to pharyngitis or impetigo, respectively...
  5. SpyA, a novel S. pyogenes ADP-ribosyltransferase
    STEPHEN L MOSELEY; Fiscal Year: 2010
    ..Infections due to this organism range from the relatively mild and common pharyngitis and impetigo to the acute and life-threatening necrotizing fasciitis and toxic shock...
  6. INTERACTION OF GROUP A STREP WITH THE PLASMINOGEN SYSTEM
    Michael Boyle; Fiscal Year: 2001
    ..Group A streptococci are significant human pathogens associated with a variety of diseases including pharyngitis, impetigo, and invasive infections such as cellulitis and bacteremia...
  7. Mechanisms of Blister Formation by Staphylococcal Toxins
    John Stanley; Fiscal Year: 2006
    ..by Staphylococcus aureus, causes staphylococcal scalded skin syndrome (SSSS) and its more localized form, bullous impetigo. The crystal structure of ETA suggests that it is a serine protease with an inactive catalytic site which becomes ..
  8. MOLECULAR PROPERTIES OF CLASS I AND II STREPTOCOCCI
    DEBRA BESSEN; Fiscal Year: 2000
    ..Although GABHS can thrive in almost any bodily tissue, it is the nasopharynx and impetigo lesion that serve as the primary sites of infection and principal reservoirs for transmission...
  9. MOLECULAR ANALYSIS OF STAPHYLOCOCCAL EXFOLIATIVE TOXIN A
    LISA PLANO; Fiscal Year: 2007
    ..We further propose to develop an animal model of staphylococcal impetigo to address the role of the exfoliative toxins in pathogenesis of these bacteria.
  10. Expansion of Rodent Biocontainment at the University of Missouri
    LONNY DIXON; Fiscal Year: 2009
    ..virus, and Listeria monocytogenes, all of which can infect humans, causing such diseases as strep throat, impetigo, and streptococcal toxic shock syndrome;miscarriage, hydrocephalus and other birth defects;and food-borne illness. ..
  11. Exfoliative toxin A and desmosomal adhesion in epidermis
    CORY SIMPSON; Fiscal Year: 2009
    Exfoliative toxin A (ETA) secreted by Staphylococcus aureus causes destruction of human epidermis in bullous impetigo and Staphylcoccal Scalded Skin Syndrome (SSSS), which renders victims vulnerable to life-threatening infections and ..
  12. GROUP A STREPTOCOCCAL INFECTIONS IN CHILDREN
    Judith Martin; Fiscal Year: 2004
    ....
  13. STREPTOCOCCAL INACTIVATOR IN HUMAN CHEMOATTRACTANTS
    Paul Cleary; Fiscal Year: 2006
    ..New data indicates that the C5a peptide required for successful colonization and persistence of streptococci in nasal associated lymphoid tissue. ..
  14. Strategies for Group A Streptococcal Prevention
    Grace Lee; Fiscal Year: 2008
    ..During her K Award, she hopes to establish herself as a multidisciplinary researcher in the fields of decision sciences, infectious disease modeling, and health policy. [unreadable] [unreadable]..
  15. T cell immune response to group A streptococci in NALT
    Paul Cleary; Fiscal Year: 2008
    ..Experiments will determine impact of infection on the antigen specific T cell response in NALT and other lymphoid organs. ..
  16. Population genomics of Streptococcus pyogenes
    DEBRA BESSEN; Fiscal Year: 2009
    ..abstract_text> ..
  17. INTRACELLULAR INFECTION BY INVASIVE GROUP A STREPTOCOCCI
    Paul Cleary; Fiscal Year: 2006
    ..Information gained from this study may identify new targets for antibiotic development, and increase our understanding of the mechanisms by which this pathogen persists in human populations. ..
  18. Molecular Evolution of Resistance in Strep. pyogenes
    DEBRA BESSEN; Fiscal Year: 2005
    ..are highly prevalent bacterial pathogens that infect the throat or skin of humans, causing pharyngitis or impetigo. GAS can trigger autoimmune disease, such as rheumatic fever, or cause life-threatening infections, such as toxic ..
  19. TRAINING GRANT IN DERMATOLOGICAL RESEARCH
    Luis Diaz; Fiscal Year: 2006
    ..This competitive grant application requests funding to support the training at the UNC Dermatology Department of the next generation of dermatological investigators. ..
  20. Tissue-Specific Infection by Group A Streptococci
    DEBRA BESSEN; Fiscal Year: 2007
    ..most often it causes only a mild infection at superficial sites - the oropharynx (strep throat) or epidermis (impetigo)...
  21. EVOLUTION OF GROUP A STREPTOCOCCI
    DEBRA BESSEN; Fiscal Year: 2004
    ..These sera will be tested to determine whether strain structure is determined by the immunogenicity of the emm and sof gene products. ..