swine diseases

Summary

Summary: Diseases of domestic swine and of the wild boar of the genus Sus.

Top Publications

  1. pmc Methicillin-resistant Staphylococcus aureus in pig farming
    Andreas Voss
    Radboud University Medical Centre, Nijmegen, The Netherlands
    Emerg Infect Dis 11:1965-6. 2005
  2. pmc Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans
    Rebecca J Garten
    WHO Collaborating Center for Influenza, Centers for Disease Control and Prevention CDC, Atlanta, GA 30333, USA
    Science 325:197-201. 2009
  3. ncbi Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic
    Gavin J D Smith
    State Key Laboratory of Emerging Infectious Diseases and Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong SAR, China
    Nature 459:1122-5. 2009
  4. pmc In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses
    Yasushi Itoh
    Department of Pathology, Shiga University of Medical Science, Ohtsu, Shiga 520 2192, Japan
    Nature 460:1021-5. 2009
  5. ncbi Nipah virus: a recently emergent deadly paramyxovirus
    K B Chua
    Department of Medical Microbiology, University of Malaya Medical Center, 50603 Kuala Lumpur, Malaysia
    Science 288:1432-5. 2000
  6. ncbi Characterization of a porcine intestinal epithelial cell line for in vitro studies of microbial pathogenesis in swine
    Peter Schierack
    Institut für Mikrobiologie und Tierseuchen, Freie Universitat Berlin, Berlin, Germany
    Histochem Cell Biol 125:293-305. 2006
  7. pmc Reassortment of pandemic H1N1/2009 influenza A virus in swine
    D Vijaykrishna
    State Key Laboratory of Emerging Infectious Diseases and Department of Microbiology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong Special Administrative Region, China
    Science 328:1529. 2010
  8. ncbi Methicillin resistant Staphylococcus aureus colonization in pigs and pig farmers
    T Khanna
    Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    Vet Microbiol 128:298-303. 2008
  9. ncbi The emergence of Staphylococcus aureus ST398
    Tara C Smith
    Department of Epidemiology, Center for Emerging Infectious Diseases, University of Iowa, Iowa City, IA 52242, USA
    Vector Borne Zoonotic Dis 11:327-39. 2011
  10. pmc Prevalence of livestock-associated MRSA in communities with high pig-densities in The Netherlands
    Brigitte A van Cleef
    Centre for Infectious Disease Control Netherlands, RIVM National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    PLoS ONE 5:e9385. 2010

Detail Information

Publications309 found, 100 shown here

  1. pmc Methicillin-resistant Staphylococcus aureus in pig farming
    Andreas Voss
    Radboud University Medical Centre, Nijmegen, The Netherlands
    Emerg Infect Dis 11:1965-6. 2005
    ..While spa-type t108 is apparently a more widespread clone among pig farmers and their environment, we did find other spa-types...
  2. pmc Antigenic and genetic characteristics of swine-origin 2009 A(H1N1) influenza viruses circulating in humans
    Rebecca J Garten
    WHO Collaborating Center for Influenza, Centers for Disease Control and Prevention CDC, Atlanta, GA 30333, USA
    Science 325:197-201. 2009
    ..Antigenically the viruses are homogeneous and similar to North American swine A(H1N1) viruses but distinct from seasonal human A(H1N1)...
  3. ncbi Origins and evolutionary genomics of the 2009 swine-origin H1N1 influenza A epidemic
    Gavin J D Smith
    State Key Laboratory of Emerging Infectious Diseases and Department of Microbiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, 21 Sassoon Road, Pokfulam, Hong Kong SAR, China
    Nature 459:1122-5. 2009
    ..Our results highlight the need for systematic surveillance of influenza in swine, and provide evidence that the mixing of new genetic elements in swine can result in the emergence of viruses with pandemic potential in humans...
  4. pmc In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses
    Yasushi Itoh
    Department of Pathology, Shiga University of Medical Science, Ohtsu, Shiga 520 2192, Japan
    Nature 460:1021-5. 2009
    ..Finally, we show that CA04 is sensitive to approved and experimental antiviral drugs, suggesting that these compounds could function as a first line of defence against the recently declared S-OIV pandemic...
  5. ncbi Nipah virus: a recently emergent deadly paramyxovirus
    K B Chua
    Department of Medical Microbiology, University of Malaya Medical Center, 50603 Kuala Lumpur, Malaysia
    Science 288:1432-5. 2000
    ..Like Hendra virus, Nipah virus is unusual among the paramyxoviruses in its ability to infect and cause potentially fatal disease in a number of host species, including humans...
  6. ncbi Characterization of a porcine intestinal epithelial cell line for in vitro studies of microbial pathogenesis in swine
    Peter Schierack
    Institut für Mikrobiologie und Tierseuchen, Freie Universitat Berlin, Berlin, Germany
    Histochem Cell Biol 125:293-305. 2006
    ..IL-8 protein expression was enhanced by Salmonella invasion. We conclude that the IPEC-J2 cell line provides a relevant in vitro model system for porcine intestinal pathogen-host cell interactions...
  7. pmc Reassortment of pandemic H1N1/2009 influenza A virus in swine
    D Vijaykrishna
    State Key Laboratory of Emerging Infectious Diseases and Department of Microbiology, Li Ka Shing Faculty of Medicine, University of Hong Kong, Hong Kong Special Administrative Region, China
    Science 328:1529. 2010
    ..Continued reassortment of H1N1/2009 with swine influenza viruses could produce variants with transmissibility and altered virulence for humans. Global systematic surveillance of influenza viruses in swine is warranted...
  8. ncbi Methicillin resistant Staphylococcus aureus colonization in pigs and pig farmers
    T Khanna
    Department of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, Ontario N1G 2W1, Canada
    Vet Microbiol 128:298-303. 2008
    ..This study demonstrates that MRSA is common in pigs in Ontario, Canada, and provides further support to concerns about transmission of MRSA between pigs and humans...
  9. ncbi The emergence of Staphylococcus aureus ST398
    Tara C Smith
    Department of Epidemiology, Center for Emerging Infectious Diseases, University of Iowa, Iowa City, IA 52242, USA
    Vector Borne Zoonotic Dis 11:327-39. 2011
    ..We also discuss lingering research questions and implications for controlling spread of this bacterium in an agricultural environment and beyond...
  10. pmc Prevalence of livestock-associated MRSA in communities with high pig-densities in The Netherlands
    Brigitte A van Cleef
    Centre for Infectious Disease Control Netherlands, RIVM National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    PLoS ONE 5:e9385. 2010
    ..This cross-sectional study aimed to determine the spread to persons not in direct contact with livestock in areas with a high density of pig farms...
  11. pmc Reproduction of mucohaemorrhagic diarrhea and colitis indistinguishable from swine dysentery following experimental inoculation with "Brachyspira hampsonii" strain 30446
    Joseph E Rubin
    Department of Veterinary Microbiology, Western College of Veterinary Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    PLoS ONE 8:e57146. 2013
    ..hampsonii" strain 30446, however was isolated. The purpose of this study was to experimentally reproduce mucohaemorrhagic colitis and characterize strain 30446 shedding following inoculation...
  12. ncbi Spa type distribution in Staphylococcus aureus originating from pigs, cattle and poultry
    H Hasman
    Technical University of Denmark, National Food Institute, Bulowsvej 27, 1790 Copenhagen V, Denmark
    Vet Microbiol 141:326-31. 2010
    ..In conclusion, strains of MSSA CC398 were commonly present in pigs but not present at all in the other reservoirs tested...
  13. ncbi Escherichia coli in postweaning diarrhea in pigs: an update on bacterial types, pathogenesis, and prevention strategies
    John M Fairbrother
    The Escherichia coli Laboratory, Faculte de Medecine Veterinaire, Universite de Montreal, 3200 Sicotte, Saint Hyacinthe, QC, Canada J2S 2M2
    Anim Health Res Rev 6:17-39. 2005
    ..To date, not a single strategy has proved to be totally effective and it is probable that the most successful approach on a particular farm will involve a combination of diet modification and other preventive measures...
  14. pmc Spatial dynamics of human-origin H1 influenza A virus in North American swine
    Martha I Nelson
    Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health, Bethesda, Maryland, United States of America
    PLoS Pathog 7:e1002077. 2011
    ....
  15. pmc Are swine workers in the United States at increased risk of infection with zoonotic influenza virus?
    Kendall P Myers
    Center for Emerging Infectious Diseases, Department of Epidemiology, University of Iowa College of Public Health, Iowa City, IA 52242, USA
    Clin Infect Dis 42:14-20. 2006
    ..Pigs have an important role in interspecies transmission of the virus. We examined multiple swine-exposed human populations in the nation's number 1 swine-producing state for evidence of previous swine influenza virus infection...
  16. ncbi Porcine circovirus type 2 associated disease: update on current terminology, clinical manifestations, pathogenesis, diagnosis, and intervention strategies
    Tanja Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA
    J Vet Diagn Invest 19:591-615. 2007
    ..This article is intended to discuss the most common disease manifestations, pathogenesis, diagnostic approaches, and intervention strategies associated with PCVAD in North America...
  17. pmc Streptococcal toxic shock syndrome caused by Streptococcus suis serotype 2
    Jiaqi Tang
    Department of Epidemiology, Research Institute for Medicine of Nanjing Command, Nanjing, China
    PLoS Med 3:e151. 2006
    ....
  18. ncbi Molecular and phylogenetic characterization of Cryptosporidium and Giardia from pigs and cattle in Denmark
    R B Langkjaer
    Department of Veterinary Diagnostics and Research, Danish Institute for Food and Veterinary Research, Bulowsvej 27, DK 1790 Copenhagen V, Denmark
    Parasitology 134:339-50. 2007
    ..Giardia isolates belonging to the zoonotic Assemblage A was found in both young and older calves, as well as in weaners and piglets, whereas cows seemed to be infected purely by isolates of the livestock group, Assemblage E...
  19. pmc Prevalence and molecular characteristics of methicillin-resistant Staphylococcus aureus (MRSA) among pigs on German farms and import of livestock-related MRSA into hospitals
    R Kock
    Institute of Hygiene, University Hospital Munster, Robert Koch Str 41, 48149, Munster, Germany
    Eur J Clin Microbiol Infect Dis 28:1375-82. 2009
    ..Our results indicate that livestock represents a relevant reservoir for the import of MRSA into regional German hospitals...
  20. ncbi Swine influenza viruses a North American perspective
    Amy L Vincent
    Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA ARS, Ames, Iowa 50010, USA
    Adv Virus Res 72:127-54. 2008
    ....
  21. ncbi Helminth parasites in pigs: new challenges in pig production and current research highlights
    A Roepstorff
    Danish Centre for Experimental Parasitology, Department for Veterinary Disease Biology, Faculty of Life Sciences, University of Copenhagen, Dyrlægevej 100, DK 1870 Frederiksberg C, Copenhagen, Denmark
    Vet Parasitol 180:72-81. 2011
    ....
  22. ncbi Molecular detection of porcine kobuviruses in pigs in Korea and their association with diarrhea
    Seong Jun Park
    Department of Veterinary Medicine Virology Lab, Seoul National University, Gwanak Gu, Korea
    Arch Virol 155:1803-11. 2010
    ....
  23. ncbi Prevalence and antimicrobial susceptibility of methicillin-resistant Staphylococcus aureus among pigs in Belgium
    Florence Crombé
    Department of General Bacteriology, CODA CERVA VAR, Brussels, Belgium
    Microb Drug Resist 18:125-31. 2012
    ..In accordance with other European countries, age-related and management-related differences in MRSA prevalence were observed that should be considered when control strategies are outlined...
  24. ncbi Influenza A virus infection dynamics in swine farms in Belgium, France, Italy and Spain, 2006-2008
    C S Kyriakis
    Laboratory of Virology, Faculty of Veterinary Medicine, Ghent University, Merelbeke, Belgium
    Vet Microbiol 162:543-50. 2013
    ..This can either be explained by the persistence of the virus in a farm, or by the periodical re-introduction of SIVs of the same subtype...
  25. ncbi Porcine epidemic diarrhoea virus: a comprehensive review of molecular epidemiology, diagnosis, and vaccines
    DaeSub Song
    Viral Infectious Disease Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 305 806, South Korea
    Virus Genes 44:167-75. 2012
    ..In the current review, we first describe the molecular and genetic characteristics of the PEDV. Then we discuss its molecular epidemiology and diagnosis, what vaccines are available, and how PEDV can be treated...
  26. pmc Lactic acid bacterial colonization and human rotavirus infection influence distribution and frequencies of monocytes/macrophages and dendritic cells in neonatal gnotobiotic pigs
    Wei Zhang
    Department of Veterinary Preventive Medicine, Ohio Agricultural Research and Development Center, The Ohio State University, Wooster, OH 44691 4096, USA
    Vet Immunol Immunopathol 121:222-31. 2008
    ....
  27. ncbi Actinobacillus pleuropneumoniae: pathobiology and pathogenesis of infection
    Janine T Bosse
    Molecular Infectious Diseases Group, Department of Paediatrics, Faculty of Medicine, Imperial College, St Mary s Campus, W2 1PG, London, UK
    Microbes Infect 4:225-35. 2002
    ....
  28. ncbi Co-existence of multiple strains of two novel porcine bocaviruses in the same pig, a previously undescribed phenomenon in members of the family Parvoviridae, and evidence for inter- and intra-host genetic diversity and recombination
    Susanna K P Lau
    State Key Laboratory of Emerging Infectious Diseases, Hong Kong SAR
    J Gen Virol 92:2047-59. 2011
    ..This is the first report describing marked sequence diversity and the co-existence of two viruses of the family Parvoviridae within the same host, which may have originated from and, in turn, facilitated recombination...
  29. ncbi Phenotypic and molecular characterization of a novel strongly hemolytic Brachyspira species, provisionally designated "Brachyspira hampsonii"
    Yogesh Chander
    Minnesota Veterinary Diagnostic Laboratory, University of Minnesota, St Paul, MN 55108, USA
    J Vet Diagn Invest 24:903-10. 2012
    ..The results suggest that a potentially virulent new species of Brachyspira sp., provisionally named "Brachyspira hampsonii ", is circulating among swine herds in the United States...
  30. pmc Immunization of pigs to prevent disease in humans: construction and protective efficacy of a Salmonella enterica serovar Typhimurium live negative-marker vaccine
    Martin Selke
    Institute for Microbiology, Department of Infectious Diseases, University of Veterinary Medicine Hannover, Hannover, Germany
    Infect Immun 75:2476-83. 2007
    ..The approach described overcomes the problems currently limiting the use of bacterial live vaccines and holds considerable potential for future developments in the field...
  31. ncbi Comparison of detection methods for Toxoplasma gondii in naturally and experimentally infected swine
    Dolores E Hill
    United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Animal Parasitic Diseases Laboratory, BARC East Beltsville, MD 20705, USA
    Vet Parasitol 141:9-17. 2006
    ..gondii infection in tissues from naturally and experimentally infected pigs. The results indicate that a serum-based ELISA is the most sensitive method, of those tested, for detection of T. gondii infected swine...
  32. ncbi Genomic characterization of H1N2 swine influenza viruses in Italy
    Ana Moreno
    Department of Virology, Istituto Zooprofilattico Sperimentale della Lombardia e dell Emilia Romagna, Via Bianchi, 9, 25124 Brescia, Italy
    Vet Microbiol 156:265-76. 2012
    ..These findings also highlighted different genomic characteristics of the NA gene the recent Italian strains compared to circulating European viruses...
  33. ncbi Onset and duration of fecal shedding, cell-mediated and humoral immune responses in pigs after challenge with a pathogenic isolate or attenuated vaccine strain of Lawsonia intracellularis
    Roberto M C Guedes
    Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Minnesota, 205 Veterinary Science Building, 1971 Commonwealth Avenue, 55108, St Paul, MN, USA
    Vet Microbiol 91:135-45. 2003
    ..In summary, both pathogenic isolate challenged and vaccine exposed pigs demonstrated long-term shedding of and immune responses to L. intracellularis...
  34. ncbi Infection and colonization with methicillin resistant Staphylococcus aureus ST398 versus other MRSA in an area with a high density of pig farms
    M W H Wulf
    PAMM Laboratory for Medical Microbiology, de Run 6250, Veldhoven, The Netherlands
    Eur J Clin Microbiol Infect Dis 31:61-5. 2012
    ..ST398 isolates were more often multi-resistant than isolates of other spa-types. The emergence of MRSA ST398 led to an increase in both MRSA carriers and MRSA infections...
  35. ncbi Diversity of antimicrobial resistance pheno- and genotypes of methicillin-resistant Staphylococcus aureus ST398 from diseased swine
    Kristina Kadlec
    Institute of Farm Animal Genetics, Friedrich Loeffler Institute FLI, Neustadt Mariensee, Germany
    J Antimicrob Chemother 64:1156-64. 2009
    ....
  36. pmc Replication, pathogenesis and transmission of pandemic (H1N1) 2009 virus in non-immune pigs
    Sharon M Brookes
    Veterinary Laboratories Agency Weybridge, EU OIE FAO Reference Laboratory for Avian Influenza and Newcastle Disease, Addlestone, Surrey, United Kingdom
    PLoS ONE 5:e9068. 2010
    ..These findings provide potential clues to the existence and biological significance of viral receptor-binding variants with 225D and 225G during the 1918 pandemic [5]...
  37. ncbi A review of porcine circovirus 2-associated syndromes and diseases
    C Chae
    Department of Veterinary Pathology, College of Veterinary Medicine and School of Agricultural Biotechnology, Seoul National University, Kwanak Gu 151 742, Seoul, Republic of Korea
    Vet J 169:326-36. 2005
    ..The extent of the involvement of PCV2 in swine disease other than PMWS is currently poorly understood. This review concentrates on PCV-2-associated syndromes and diseases other than PMWS...
  38. pmc Cases of swine influenza in humans: a review of the literature
    Kendall P Myers
    Center for Emerging Infectious Diseases, Department of Epidemiology, College of Public Health, University of Iowa, Iowa City, IA, USA
    Clin Infect Dis 44:1084-8. 2007
    ..Because prior studies have shown that persons who work with swine are at increased risk of zoonotic influenza virus infection, it is prudent to include them in pandemic planning efforts...
  39. pmc Pathogenesis of pandemic influenza A (H1N1) and triple-reassortant swine influenza A (H1) viruses in mice
    Jessica A Belser
    Influenza Division, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30333, USA
    J Virol 84:4194-203. 2010
    ..Taken together, these studies demonstrate that the 2009 H1N1 viruses exhibited mild to moderate virulence in mice compared with highly pathogenic viruses...
  40. pmc Virulence factors of Actinobacillus pleuropneumoniae involved in colonization, persistence and induction of lesions in its porcine host
    Koen Chiers
    Department of Pathology, Bacteriology and Poultry Diseases, Faculty of Veterinary Medicine, Ghent University, Ghent, Belgium
    Vet Res 41:65. 2010
    ..Information on virulence factors involved in tonsillar and nasal cavity colonization and persistence is scarce, but it can be speculated that similar features as demonstrated for the lung may play a role...
  41. pmc Prevalence and risk factors of porcine cysticercosis in Angónia District, Mozambique
    Alberto Pondja
    Faculty of Veterinary Medicine, Eduardo Mondlane University, Maputo, Mozambique
    PLoS Negl Trop Dis 4:e594. 2010
    ....
  42. ncbi Experimental reproduction of postweaning multisystemic wasting syndrome in pigs by dual infection with Mycoplasma hyopneumoniae and porcine circovirus type 2
    T Opriessnig
    Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011 1250, USA
    Vet Pathol 41:624-40. 2004
    ..This study indicates that M. hyopneumoniae potentiates the severity of PCV2-associated lung and lymphoid lesions, increases the amount and prolongs the presence of PCV2-antigen, and increases the incidence of PMWS in pigs...
  43. ncbi The epidemiology and evolution of influenza viruses in pigs
    I H Brown
    Veterinary Laboratories Agency Weybridge, New Haw, Addlestone, UK
    Vet Microbiol 74:29-46. 2000
    ..Both human H3N2 and avian H1N1 were detected in pigs many years before they acquired the ability to spread rapidly and become associated with disease epidemics in pigs...
  44. pmc Genetic and pathobiologic characterization of pandemic H1N1 2009 influenza viruses from a naturally infected swine herd
    Hana M Weingartl
    Canadian Food Inspection Agency CFIA, National Centre for Foreign Animal Disease NCFAD, Manitoba, Canada
    J Virol 84:2245-56. 2010
    ..This, along with the somewhat irregular pathobiological characteristics observed in experimentally infected animals, suggests that although the virus may be of swine origin, significant viral evolution may still be ongoing...
  45. ncbi Porcine circovirus diseases
    Joaquim Segales
    Virology Department, Veterinary Research Laboratory, Veterinary Sciences Division, Stoney Road Stormont, DARDNI, Stormont, BT4 SD Belfast, Northern Ireland, UK
    Anim Health Res Rev 6:119-42. 2005
    ....
  46. ncbi Streptococcus suis infections in humans: the Chinese experience and the situation in North America
    Marcelo Gottschalk
    Centre de Recherche en Infectiologie Porcine CRIP, Faculte de Medecine Veterinaire, Universite de Montreal, 3200 rue Sicotte, St Hyacinthe, Quebec, J2S 2M2, Canada
    Anim Health Res Rev 8:29-45. 2007
    ..Here, we review the epidemiological, clinical and immunopathological features of S. suis infection in humans...
  47. ncbi Molecular epidemiology of porcine epidemic diarrhea virus in China
    Jianfei Chen
    Division of Swine Infectious Diseases, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People s Republic of China
    Arch Virol 155:1471-6. 2010
    ..Chinese PEDV field strains (excluding CH/GSJIII/07) can be differentiated from PEDV vaccine strains by a nested RT-PCR method...
  48. ncbi Prevalence, antibiotic resistance and molecular characterisation of Staphylococcus aureus in pigs at agricultural fairs in the USA
    A E Dressler
    Center for Emerging Infectious Diseases, University of Iowa College of Public Health, 105 River Street S431, Iowa City, IA 52242, USA
    Vet Rec 170:495. 2012
    ..These results verify the presence of antibiotic-resistant S aureus in pigs exhibited at USA fairs, suggesting that pigs are a potential reservoir for S aureus within this environment...
  49. ncbi Longitudinal investigation of methicillin-resistant Staphylococcus aureus in piglets
    J S Weese
    Department of Pathobiology, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada
    Zoonoses Public Health 58:238-43. 2011
    ..No piglets or sows received antimicrobials during the study period. These results indicate that age must be considered when designing surveillance programmes and interpreting results of different studies on MRSA...
  50. ncbi Pre-infection of pigs with Mycoplasma hyopneumoniae modifies outcomes of infection with European swine influenza virus of H1N1, but not H1N2, subtype
    C Deblanc
    Anses, Ploufragan Plouzane Laboratory, Swine Virology Immunology Unit, Ploufragan, France
    Vet Microbiol 157:96-105. 2012
    ..This experimental model of coinfection with Mhp and avian-like swine H1N1 is a relevant tool for studying the pathogenesis of SIV-associated PRDC and testing intervention strategies for the control of the disease...
  51. pmc Colonization and transmission of methicillin-resistant Staphylococcus aureus ST398 in nursery piglets
    Florence Crombé
    Veterinary and Agrochemical Research Centre, Department of Bacterial Diseases, Ukkel, Belgium
    Appl Environ Microbiol 78:1631-4. 2012
    ..Reproduction ratios (R(0)) in three experimental groups were found to vary between 3.92 and 52.54, indicating that after introduction, MRSA ST398 will spread easily among weaned piglets, with a tendency to become established...
  52. ncbi Novel H1N2 swine influenza reassortant strain in pigs derived from the pandemic H1N1/2009 virus
    Ana Moreno
    Istituto Zooprofilattico Sperimentale della Lombardia e dell Emilia Romagna IZSLER, Via Bianchi, 9, 25124 Brescia, Italy
    Vet Microbiol 149:472-7. 2011
    ..The new reassortant not only represents a pandemic (zoonotic) threat but also has unknown livestock implications for the European swine industry...
  53. ncbi First detection of kobuvirus in farm animals in Brazil and the Netherlands
    Aline F Barry
    Universidade Estadual de Londrina, Londrina, Brazil Central Veterinary Institute, Wageningen University and Research Centre, Lelystad, The Netherlands
    Infect Genet Evol 11:1811-4. 2011
    ..The data presented in this study contribute to the comprehension of kobuvirus epidemiology and also to the molecular identification of kobuvirus strains circulating worldwide...
  54. ncbi Immune and acute phase response in pigs experimentally infected with H1N2 swine influenza virus
    Małgorzata Pomorska-Mól
    Department of Swine Diseases, National Veterinary Research Institute, Puławy, Poland
    FEMS Immunol Med Microbiol 66:334-42. 2012
    ..g. vaccine efficiency investigations) or as a marker for disease severity, but to confirm this hypothesis more studies are needed...
  55. pmc New variants of porcine epidemic diarrhea virus, China, 2011
    Wentao Li
    Huazhong Agricultural University, Wuhan, People s Republic of China
    Emerg Infect Dis 18:1350-3. 2012
    ..Three new PEDV variants were identified...
  56. pmc Swine workers and swine influenza virus infections
    Gregory C Gray
    University of Iowa College of Public Health, Iowa City, Iowa, USA
    Emerg Infect Dis 13:1871-8. 2007
    ..Study data suggest that swine workers and their nonswine-exposed spouses are at increased risk of zoonotic influenza virus infections...
  57. pmc Development and characterization of protective Haemophilus parasuis subunit vaccines based on native proteins with affinity to porcine transferrin and comparison with other subunit and commercial vaccines
    Rafael Frandoloso
    Department of Animal Health, University of Leon, 24007 Leon, Spain
    Clin Vaccine Immunol 18:50-8. 2011
    ..parasuis, thus suggesting their effectiveness in preventing Glässer's disease outbreaks caused by serovar 5...
  58. ncbi Molecular characterization and phylogenetic analysis of porcine epidemic diarrhea virus (PEDV) field isolates in Korea
    Seong Jun Park
    Department of Veterinary Medicine Virology Lab, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, Gwanak Gu, Seoul, Korea
    Arch Virol 156:577-85. 2011
    ..These results raise questions as to whether a new type of PEDV vaccine may be necessary for preventing PEDV infection more effectively in Korea...
  59. ncbi Hyperendemic human and porcine Taenia solium infection in Perú
    Hector H Garcia
    Department of Microbiology, Universidad Peruana Cayetano Heredia, Lima, Peru
    Am J Trop Med Hyg 68:268-75. 2003
    ..Besides confirming the close relationship between taeniasis and cysticercosis cases, this large-scale field study demonstrated early age of tapeworm and cysticercosis infections in humans, and short duration of taeniasis infections...
  60. ncbi Retrospective study on swine Torque teno virus genogroups 1 and 2 infection from 1985 to 2005 in Spain
    Joaquim Segales
    Centre de Recerca en Sanitat Animal, UAB IRTA, Campus de la Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Vet Microbiol 134:199-207. 2009
    ..This study represents the earliest evidence of TTV infection in pigs to date, 14 years before the initial description of this virus. Moreover, this is also the earliest evidence of TTV infection in any species...
  61. pmc Wild boars as sources for infectious diseases in livestock and humans
    X J Meng
    Center for Molecular Medicine and Infectious Diseases, Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, CRC Integrated Life Sciences Building, Blacksburg, VA 24061 0913, USA
    Philos Trans R Soc Lond B Biol Sci 364:2697-707. 2009
    ..This article discusses the prevalence and risk of infectious agents in wild boars and their potential transmission to livestock and humans...
  62. ncbi A Bayesian approach for estimating values for prevalence and diagnostic test characteristics of porcine cysticercosis
    P Dorny
    Department of Animal Health, Prince Leopold Institute of Tropical Medicine, Antwerp, Belgium
    Int J Parasitol 34:569-76. 2004
    ..A Bayesian analysis framework offers the possibility to combine prior opinion with experimental data to more accurately estimate the real prevalence of porcine cysticercosis in the absence of a gold standard...
  63. ncbi Evidence for recombination in natural populations of porcine circovirus type 2 in Hong Kong and mainland China
    Ching Man Ma
    Department of Zoology, The University of Hong Kong, Hong Kong SAR
    J Gen Virol 88:1733-7. 2007
    ....
  64. ncbi Prevalence of swine Torque teno virus in post-weaning multisystemic wasting syndrome (PMWS)-affected and non-PMWS-affected pigs in Spain
    Tuija Kekarainen
    Centre de Recerca en Sanitat Animal CReSA, Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    J Gen Virol 87:833-7. 2006
    ..These results indicate a high prevalence of both swine TTV genogroups in Spain, being present more frequently in PMWS-affected animals than in non-PMWS-affected animals...
  65. ncbi Comparison of the pathogenicity of two US porcine reproductive and respiratory syndrome virus isolates with that of the Lelystad virus
    P G Halbur
    Veterinary Diagnostic Laboratory, Iowa State University, Ames, USA
    Vet Pathol 32:648-60. 1995
    ..This work demonstrated a marked difference in pathogenicity of porcine reproductive and respiratory syndrome isolates...
  66. ncbi Detection and characterization of infectious Hepatitis E virus from commercial pig livers sold in local grocery stores in the USA
    A R Feagins
    Center for Molecular Medicine and Infectious Diseases, Department of Biomedical Sciences and Pathobiology, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
    J Gen Virol 88:912-7. 2007
    ..The data demonstrated that commercial pig livers sold in grocery stores are contaminated by HEV and that the contaminating virus remains infectious, thus raising a public-health concern for food-borne HEV infection...
  67. ncbi Characterization of an influenza A virus isolated from pigs during an outbreak of respiratory disease in swine and people during a county fair in the United States
    Amy L Vincent
    Virus and Prion Diseases of Livestock Research Unit, National Animal Disease Center, USDA, Agricultural Research Service, Ames, IA 50010, USA
    Vet Microbiol 137:51-9. 2009
    ..The characteristics of the OH07 virus in our pig experimental model as well as the documented human transmission warrant close monitoring of the spread of this virus in pig and human populations...
  68. ncbi Genetic and antigenic evolution of swine influenza viruses in Europe and evaluation of their zoonotic potential
    G Kuntz-Simon
    Swine Virology and Immunology Unit, Research Laboratory on Poultry, Swine and Fish, French Agency for Food Safety, Ploufragan, France
    Zoonoses Public Health 56:310-25. 2009
    ..Our present understanding of the transmission of European SIVs from pigs to other animal species and to humans, together with the factors that limit inter-species transmission, is described...
  69. pmc Chinese-like strain of porcine epidemic diarrhea virus, Thailand
    Suphasawatt Puranaveja
    Chulalongkorn University, Bangkok, Thailand
    Emerg Infect Dis 15:1112-5. 2009
    ..Phylogenetic analysis places all Thai PEDV isolates during the outbreaks in the same clade as the Chinese strain JS-2004-2. This new genotype PEDV is prevailing and currently causing sporadic outbreaks in Thailand...
  70. ncbi Unexpected sequence types in livestock associated methicillin-resistant Staphylococcus aureus (MRSA): MRSA ST9 and a single locus variant of ST9 in pig farming in China
    Jaap A Wagenaar
    Department of Infectious Diseases and Immunology, Faculty of Veterinary Medicine, Utrecht University, P O Box 80 165, 3508 TD Utrecht, The Netherlands
    Vet Microbiol 139:405-9. 2009
    ..The study confirms that livestock may act as a reservoir for MRSA...
  71. pmc Clonal comparison of Staphylococcus aureus isolates from healthy pig farmers, human controls, and pigs
    Laurence Armand-Lefevre
    Bacteriology Laboratory, Groupe Hospitalier Bichat Claude Bernard, Paris, France
    Emerg Infect Dis 11:711-4. 2005
    ..This finding suggests a high rate of strain exchange between pigs and farmers...
  72. ncbi Risk factors associated with pleuritis and cranio-ventral pulmonary consolidation in slaughter-aged pigs
    L Fraile
    Centre de Recerca en Sanitat Animal CReSA, UAB IRTA, Campus de la Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Vet J 184:326-33. 2010
    ..59) that cranio-ventral pulmonary consolidation lesions (EP-like lesions) were affected by the type of farm ventilation, the presence of respiratory symptoms during the fattening period and Mhyo and SIV H1N2 herd seroprevalence...
  73. ncbi Combined human and porcine mass chemotherapy for the control of T. solium
    H H Garcia
    Department of Microbiology, Universidad Peruana Cayetano Heredia, San Martin de Porras, Lima, Peru
    Am J Trop Med Hyg 74:850-5. 2006
    ..Mass chemotherapy was effective in decreasing infection pressure in this hyperendemic area. However, the magnitude of the effect was small and did not attain the goal of eliminating transmission...
  74. pmc An investigation into human pandemic influenza virus (H1N1) 2009 on an Alberta swine farm
    Krista J Howden
    Terrestrial Animal Health Division, Canadian Food Inspection Agency, Ottawa, Ontario
    Can Vet J 50:1153-61. 2009
    ..The source of virus in this herd was determined to be an infected human. Zoonotic transmission to 2 individuals responding to the outbreak was suspected and recommendations to prevent occupational exposure are discussed...
  75. ncbi Molecular characterization of porcine TT virus, an orphan virus, in pigs from six different countries
    N E McKeown
    Center for Molecular Medicine and Infectious Diseases, College of Veterinary Medicine, Virginia Polytechnic Institute and State University, 1410 Price s Fork Road, Blacksburg, VA 24061 0342, USA
    Vet Microbiol 104:113-7. 2004
    ..There are also concerns for risk of potential human infection during xenotransplantation...
  76. pmc Emergence of methicillin-resistant Staphylococcus aureus of animal origin in humans
    Inge van Loo
    Elisabeth Hospital, Tilburg, The Netherlands
    Emerg Infect Dis 13:1834-9. 2007
    ..This study shows that MRSA from an animal reservoir has recently entered the human population and is now responsible for >20% of all MRSA in the Netherlands...
  77. ncbi Heterogeneity in spike protein genes of porcine epidemic diarrhea viruses isolated in Korea
    Dong Kyu Lee
    Department of Microbiology, College of Natural Sciences, Kyungpook National University, Daegu 702 701, Republic of Korea
    Virus Res 149:175-82. 2010
    ..Therefore, our data implicates a potential usefulness of the partial S protein gene including the N-terminal region in unveiling genetic relatedness of PEDV isolates...
  78. ncbi Case-control study of risk factors for human infection with a new zoonotic paramyxovirus, Nipah virus, during a 1998-1999 outbreak of severe encephalitis in Malaysia
    U D Parashar
    Respiratory and Enteric Viruses Branch, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Infect Dis 181:1755-9. 2000
    ..The outbreak stopped after pigs in the affected areas were slaughtered and buried. Direct, close contact with pigs was the primary source of human Nipah infection, but other sources, such as infected dogs and cats, cannot be excluded...
  79. pmc Antigenic and genetic evolution of swine influenza A (H3N2) viruses in Europe
    J C de Jong
    National Influenza Center, Department of Virology, Erasmus Medical Center, P O Box 1738, 3000 DR Rotterdam, The Netherlands
    J Virol 81:4315-22. 2007
    ..Our data suggest that humoral immunity in the population plays a smaller role in the evolutionary selection processes of swine H3N2 viruses than in human H3N2 viruses...
  80. ncbi In utero transmission of porcine torque teno viruses
    Tanja Pozzuto
    Charite Universitaetsmedizin, Campus Benjamin Franklin, Medizinische Clinik II Kardiologie und Pulmonologie, Hindenburgdamm 30, 12200 Berlin, Germany
    Vet Microbiol 137:375-9. 2009
    ..These data demonstrate that porcine TTV may be transmitted to piglets by the in utero route and that the incidence of fetal infection is high...
  81. pmc Swine influenza virus infection dynamics in two pig farms; results of a longitudinal assessment
    Meritxell Simon-Grifé
    Centre de Recerca en Sanitat Animal CReSA, UAB IRTA, Campus de la Universitat Autonoma de Barcelona, 08193 Bellaterra, Barcelona, Spain
    Vet Res 43:24. 2012
    ..These findings led us to propose that influenza virus infection in pigs might present different patterns, from an epidemic outbreak to an endemic form with different waves of infections with a lower incidence...
  82. pmc Mycoplasma suis invades porcine erythrocytes
    K Groebel
    Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 270, 8057 Zurich, Switzerland
    Infect Immun 77:576-84. 2009
    ..In addition, an intracellular life cycle may explain the chronic nature of hemotrophic mycoplasma infections and should serve as the foundation for novel strategies in hemotrophic mycoplasma research (e.g., treatment or prophylaxis)...
  83. pmc Molecular detection of Torque teno virus in different breeds of swine
    Zhiwei Wu
    School of Life Science, Sichuan University, Animal Disease Prevention and Food Safety Key Laboratory of Sichuan Province, 985 Project Science Innovative Platform for Resource and Environment Protection of Southwestern, Chengdu, Sichuan, 610065, P R China
    Virol J 8:503. 2011
    ..Very little information is known about the investigations of TTV prevalence in different swine breeds so far...
  84. ncbi Zinc resistance of Staphylococcus aureus of animal origin is strongly associated with methicillin resistance
    Lina M Cavaco
    Research Group for Antimicrobial Resistance and Molecular Epidemiology, National Food Institute, Technical University of Denmark, Copenhagen, Denmark
    Vet Microbiol 150:344-8. 2011
    ..This study showed that zinc resistance and the czrC gene are widespread among CC398 MRSA isolates. This suggests that the use of zinc in feed might have contributed to the emergence of MRSA...
  85. ncbi Characterization of influenza a outbreaks in Minnesota swine herds and measures taken to reduce the risk of zoonotic transmission
    A Beaudoin
    Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, Saint Paul, MN 55108, USA
    Zoonoses Public Health 59:96-106. 2012
    ..Inconsistent use of protective equipment and employee vaccination at swine farms indicates the need for further discussion and research of approaches to minimize interspecies influenza transmission on swine farms...
  86. ncbi Clostridial enteric infections in pigs
    J Glenn Songer
    Department of Veterinary Science and Microbiology, The University of Arizona, Tucson 85721, USA
    J Vet Diagn Invest 17:528-36. 2005
    ..Clostridium difficile can also be a normal inhabitant of the intestine of healthy pigs, and diagnosis of enteric infection with this microorganism is based on detection of its toxins in feces or intestinal contents...
  87. pmc Trypanosoma vivax, T. congolense "forest type" and T. simiae: prevalence in domestic animals of sleeping sickness foci of Cameroon
    H Nimpaye
    Laboratoire de Biologie Générale, Département de Biologie et Physiologie Animales, Faculte des Sciences, Universite de Yaounde I, BP 812, Yaounde, Cameroun
    Parasite 18:171-9. 2011
    ..The high prevalences of 7 vivax and T congolense "forest type" in Bipindi and Fontem-Center indicate their intense transmission in these foci...
  88. pmc The increase of methicillin-resistant Staphylococcus aureus (MRSA) and the presence of an unusual sequence type ST49 in slaughter pigs in Switzerland
    Gudrun Overesch
    Institute of Veterinary Bacteriology, Vetsuisse Faculty, University of Bern, Langgass strasse 122, CH 3012 Bern, Switzerland
    BMC Vet Res 7:30. 2011
    ..Monitoring should determine if the overall prevalence of MRSA in the entire country is increasing over the years and if specific multi-resistant MRSA clones are spreading over the country...
  89. ncbi Livestock associated methicillin-resistant Staphylococcus aureus (LaMRSA) isolated from lesions of pigs at necropsy in northwest Germany between 2004 and 2007
    D Meemken
    Field Station for Epidemiology, University of Veterinary Medicine Hannover, Foundation, Bakum, Germany
    Zoonoses Public Health 57:e143-8. 2010
    ..We assume that MRSA in pigs may have occurred earlier than 2004 and might be not really 'emerging', but rather have been overlooked until recently. The potentially causative role of the MRSA in the lesions warrants further investigation...
  90. ncbi The British pig health schemes: integrated systems for large-scale pig abattoir lesion monitoring
    M J Sanchez-Vazquez
    Scottish Agricultural College, Kings Buildings, West Mains Road, Edinburgh, EH9 3JG, UK
    Vet Rec 169:413. 2011
    ..Additionally, they offer the added value of providing nationwide disease monitoring information and have the potential to be a useful surveillance tool for emerging and enzootic conditions...
  91. pmc First time molecular detection and phylogenetic relationships of torque teno sus virus 1 and 2 in domestic pigs in Uganda: further evidence for a global distribution
    Matilda Brink
    Section of Virology, Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden
    Virol J 9:39. 2012
    ..Therefore, the aim of this study was to investigate the possible presence of the two viruses in domestic pigs in Uganda, and describe the phylogenetic relationships to those in the rest of the world...
  92. ncbi Development of a multilocus sequence typing scheme for intestinal spirochaetes within the genus Brachyspira
    T Råsbäck
    Department of Bacteriology, National Veterinary Institute SVA, SE 751 89 Uppsala, Sweden
    Microbiology 153:4074-87. 2007
    ..This is a first step towards establishing an MLST system for use in identifying Brachyspira species and determining relationships between individual strains and species in the genus...
  93. pmc Isolation and molecular characterization of genotype 1 Japanese encephalitis virus, SX09S-01, from pigs in China
    Qi S Cao
    State Key Laboratory of Agricultural Microbiology, Huazhong Agricultural University, Wuhan City 430070, Hubei Province, PR China
    Virol J 8:472. 2011
    ..Pigs play a critical role in Japanese encephalitis virus (JEV) transmission between mosquitos and humans. In 2009, lots of piglets developed symptom of viral encephalitis in a pig farm in Yunchen, Shanxi province...
  94. ncbi A meta-analysis comparing the effect of PCV2 vaccines on average daily weight gain and mortality rate in pigs from weaning to slaughter
    Charlotte Sonne Kristensen
    Danish Agriculture and Food Council, Pig Research Centre, Vinkelvej 11, DK 8620 Kjellerup, Denmark
    Prev Vet Med 98:250-8. 2011
    ..4%) and nursery-finishing pigs (5.4%), but not for nursery pigs (0.25%). Herds negative for PRRS had a significantly larger increase in ADG compared to herds positive for PRRS. The PRRS status had no effect on mortality rate...
  95. ncbi Persistence of pseudorabies virus in feral swine populations
    Joseph L Corn
    Southeastern Cooperative Wildlife Disease Study, University of Georgia, Athens 30602, USA
    J Wildl Dis 40:307-10. 2004
    ..Consistent results from latex agglutination tests conducted in the field and laboratory demonstrated that this test was useful as a rapid and reliable diagnostic tool when used in the field...
  96. ncbi A study of the prevalence of methicillin-resistant Staphylococcus aureus in pigs and in personnel involved in the pig industry in Ireland
    Marianne Horgan
    Teagasc Food Research Centre, Moorepark, Fermoy, Co Cork, Ireland
    Vet J 190:255-9. 2011
    ..These results indicate that porcine colonisation by MRSA, and in particular the animal-related strain MRSA-ST398, was not common in Ireland during the period of study...
  97. ncbi Genetic characterization of Toxoplasma gondii isolates from pigs in southwestern China
    Peng Zhou
    Laboratory of Animal Parasitology, Shanghai Veterinary Research Institute, CAAS, Shanghai 200241, China
    J Parasitol 97:1193-5. 2011
    ..gondii isolates from pigs in China's southwestern Yunnan Province, the results of which have implications for the prevention and control of T. gondii infections in humans and other animals...
  98. ncbi Brachyspira intermedia strain diversity and relationships to the other indole-positive Brachyspira species
    Nyree D Phillips
    Animal Research Institute, School of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, Western Australia 6150, Australia
    Vet Microbiol 143:246-54. 2010
    ..hyodysenteriae, and 4 isolates of "B. suanatina", it is difficult to justify including all weakly haemolytic indole-positive Brachyspira isolates in the single species B. intermedia...
  99. ncbi Development and use of a multiplex real-time quantitative polymerase chain reaction assay for detection and differentiation of Porcine circovirus-2 genotypes 2a and 2b in an epidemiological survey
    Carl A Gagnon
    Faculte de Medecine Veterinaire, Universite de Montreal, 3200 rue Sicotte, St Hyacinthe, Quebec, Canada
    J Vet Diagn Invest 20:545-58. 2008
    ....
  100. ncbi Taenia solium porcine cysticercosis: viability of cysticerci and persistency of antibodies and cysticercal antigens after treatment with oxfendazole
    C S Sikasunge
    School of Veterinary Medicine, University of Zambia, P O Box 32379, Lusaka, Zambia
    Vet Parasitol 158:57-66. 2008
    ....
  101. ncbi Isospora suis: an experimental model for mammalian intestinal coccidiosis
    H C Mundt
    Bayer HealthCare AG, 51368, Leverkusen, Germany
    Parasitol Res 98:167-75. 2006
    ..A negative correlation between excretion and diarrhoea may be responsible for the difficulties in the detection of the parasite in field samples...

Research Grants20

  1. Development of an additive model to study the significance of heat-labile and hea
    Weiping Zhang; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  2. Pathogenesis of EAST1 toxin in ETEC associated diarrhea disease
    Weiping Zhang; Fiscal Year: 2008
    ..The determination of virulence significance of EAST1 toxin in diarrheal disease will provide essential information to prevent or control this disease. [unreadable] [unreadable] [unreadable] [unreadable]..
  3. Molecular Determinants of Virulence Porcine Circovirus 2
    Steven Krakowka; Fiscal Year: 2007
    ..Collectively, these data will provide critical insight into pathogenic mechanisms of disease mediated by mammalian circoviruses and will provide key guidance for the future study of human circovirus pathogens. ..
  4. Human Metapneumovirus in High Risk Populations
    Gregory Gray; Fiscal Year: 2005
    ..These data will facilitate the development of more comprehensive epidemiological studies, and guide future intervention studies in reducing HMPV morbidity. ..
  5. Population-based Surveillance for Zoonotic Influenza A
    Gregory Gray; Fiscal Year: 2005
    ..We are particularly well suited to conduct this work as we have extensive experience conducting both epidemiological and laboratory-based studies of respiratory pathogens. ..
  6. Functional analysis of C. perfringens epsilon toxin
    J Songer; Fiscal Year: 2006
    ..This information can be used to model the mode of action of ETX, and to define regions of the molecule that could be targeted for immunoprophylaxis and treatment. ..
  7. MUCOSAL DEFENSE MECHANISMS IN SUBSTANCE ABUSE
    David R Brown; Fiscal Year: 2010
    ....
  8. ZOONOTIC AND XENOZOONOTIC RISKS OF HEPATITIS E VIRUS
    Xiang Jin Meng; Fiscal Year: 2001
    ..abstract_text> ..
  9. Role of iNOS and CAT-2 in defense against CP infection
    Jody Gookin; Fiscal Year: 2006
    ..parvum infection. The PI is presently in the 3rd year of a 5-year K08 from NIDDK. These studies are anticipated to generate key preliminary data for the PI's first R01 application ..
  10. Pathogenesis of Infectious in Swine with Pathogenic Avian Influenza Viruses
    BH JANKE; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  11. Lethality of H5N1 Influenza Virus is Linked to TGF-beta
    Stacey Schultz Cherry; Fiscal Year: 2009
    ..These studies provide a unique opportunity to understand the cellular and immunological basis of H5N1 influenza virus virulence in mammals: currently, an unexplored area of investigation. ..
  12. NO& Epithelial Repair in Cryptosporidiosis
    Jody Gookin; Fiscal Year: 2006
    ..abstract_text> ..
  13. Novel Integrative Genetic Elements of Mycoplasmas
    Michael Calcutt; Fiscal Year: 2003
    ....
  14. Host range restriction of human influenza viruses
    Christopher Olsen; Fiscal Year: 2009
    ..abstract_text> ..
  15. Biofilm growth and detachment of an oral pathogen
    Jeffrey Kaplan; Fiscal Year: 2007
    ..abstract_text> ..
  16. Non-replicative Vaccine for Human Brucellosis
    Ramesh Vemulapalli; Fiscal Year: 2011
    ..At present there is no vaccine available for prevention of brucellosis in humans. Research proposed in this application focuses on developing a highly effective and safe Brucella vaccine for human use. ..
  17. Protease Activation of Newcastle Disease Virus for Oncolytic viral therapy
    ELANKUMARAN SUBBIAH; Fiscal Year: 2008
    ..Our approach will yield a protease-targeted oncolytic virus that can be individualized according to the patient. [unreadable] [unreadable] [unreadable] [unreadable]..
  18. B.abortus-based vaccine against viral hemorrhagic fevers
    Ramesh Vemulapalli; Fiscal Year: 2004
    ..abstract_text> ..