sheep diseases

Summary

Summary: Diseases of domestic and mountain sheep of the genus Ovis.

Top Publications

  1. pmc Pathogenesis of bovine spongiform encephalopathy in sheep
    L J M van Keulen
    Department of Bacteriology and TSE s, Central Institute for Animal Disease Control CIDC, Wageningen University and Research Centre, P O Box 2004, 8203 AA Lelystad, The Netherlands
    Arch Virol 153:445-53. 2008
  2. ncbi Echinococcosis: a review
    Pedro Moro
    Immunization Safety Office, Office of the Director, Centers for Disease Control and Prevention, 1600 Clifton Road, MS D26, Atlanta, Georgia 30333, USA
    Int J Infect Dis 13:125-33. 2009
  3. ncbi The Q fever epidemic in The Netherlands: history, onset, response and reflection
    H I J Roest
    Department of Bacteriology and TSEs, Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands
    Epidemiol Infect 139:1-12. 2011
  4. ncbi Routes of transmission and consequences of small ruminant lentiviruses (SRLVs) infection and eradication schemes
    Ernst Peterhans
    Institute of Veterinary Virology, University of Bern, Bern, Switzerland
    Vet Res 35:257-74. 2004
  5. pmc Ovine TRIM5α can restrict visna/maedi virus
    P Jáuregui
    Instituto de Agrobiotecnologia, CSIC UPNA Gobierno de Navarra, Mutilva Baja, Navarra, Spain
    J Virol 86:9504-9. 2012
  6. ncbi Effect of ewe ovine lentivirus infection on ewe and lamb productivity
    J E Keen
    US Meat Animal Research Center, USDA, Clay Center, NE 68933, USA
    Prev Vet Med 30:155-69. 1997
  7. ncbi A combined microscopic-molecular method for the diagnosis of strongylid infections in sheep
    Nathan J Bott
    Department of Veterinary Science, The University of Melbourne, 250 Princes Highway, Werribee, VIC 3030, Australia
    Int J Parasitol 39:1277-87. 2009
  8. ncbi Characterization of new small ruminant lentivirus subtype B3 suggests animal trade within the Mediterranean Basin
    L Bertolotti
    Dipartimento di Produzioni Animali, Universita degli Studi di Torino, Grugliasco, Italy
    J Gen Virol 92:1923-9. 2011
  9. ncbi An innovative survey underlining the significant level of contamination by Toxoplasma gondii of ovine meat consumed in France
    Lénaïg Halos
    ENVA AFSSA INRA UMR BIPAR, National Reference Laboratory for Food Borne Parasites, 23 Avenue du Général de Gaulle, 94700 Maisons Alfort, France
    Int J Parasitol 40:193-200. 2010
  10. ncbi Transmission of small ruminant lentiviruses
    B A Blacklaws
    Department of Clinical Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK
    Vet Microbiol 101:199-208. 2004

Detail Information

Publications306 found, 100 shown here

  1. pmc Pathogenesis of bovine spongiform encephalopathy in sheep
    L J M van Keulen
    Department of Bacteriology and TSE s, Central Institute for Animal Disease Control CIDC, Wageningen University and Research Centre, P O Box 2004, 8203 AA Lelystad, The Netherlands
    Arch Virol 153:445-53. 2008
    ..These findings indicate a spread of the BSE agent in sheep from the enteric nervous system through parasympathetic and sympathetic nerves to the medulla oblongata and the spinal cord...
  2. ncbi Echinococcosis: a review
    Pedro Moro
    Immunization Safety Office, Office of the Director, Centers for Disease Control and Prevention, 1600 Clifton Road, MS D26, Atlanta, Georgia 30333, USA
    Int J Infect Dis 13:125-33. 2009
    ..Despite some progress in the control of echinococcosis, this zoonosis continues to be a major public health problem in several countries, and in several others it constitutes an emerging and re-emerging disease...
  3. ncbi The Q fever epidemic in The Netherlands: history, onset, response and reflection
    H I J Roest
    Department of Bacteriology and TSEs, Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands
    Epidemiol Infect 139:1-12. 2011
    ..In general good monitoring and surveillance systems are necessary to assess the real magnitude of Q fever...
  4. ncbi Routes of transmission and consequences of small ruminant lentiviruses (SRLVs) infection and eradication schemes
    Ernst Peterhans
    Institute of Veterinary Virology, University of Bern, Bern, Switzerland
    Vet Res 35:257-74. 2004
    ..This paper brings together existing information regarding these questions and identifies areas for future research...
  5. pmc Ovine TRIM5α can restrict visna/maedi virus
    P Jáuregui
    Instituto de Agrobiotecnologia, CSIC UPNA Gobierno de Navarra, Mutilva Baja, Navarra, Spain
    J Virol 86:9504-9. 2012
    ..Identification of TRIM5α active molecular species may open new prophylactic strategies against lentiviral infections...
  6. ncbi Effect of ewe ovine lentivirus infection on ewe and lamb productivity
    J E Keen
    US Meat Animal Research Center, USDA, Clay Center, NE 68933, USA
    Prev Vet Med 30:155-69. 1997
    ....
  7. ncbi A combined microscopic-molecular method for the diagnosis of strongylid infections in sheep
    Nathan J Bott
    Department of Veterinary Science, The University of Melbourne, 250 Princes Highway, Werribee, VIC 3030, Australia
    Int J Parasitol 39:1277-87. 2009
    ..e. 'egg count reduction') testing or control programmes, particularly following semi- or full-automation...
  8. ncbi Characterization of new small ruminant lentivirus subtype B3 suggests animal trade within the Mediterranean Basin
    L Bertolotti
    Dipartimento di Produzioni Animali, Universita degli Studi di Torino, Grugliasco, Italy
    J Gen Virol 92:1923-9. 2011
    ....
  9. ncbi An innovative survey underlining the significant level of contamination by Toxoplasma gondii of ovine meat consumed in France
    Lénaïg Halos
    ENVA AFSSA INRA UMR BIPAR, National Reference Laboratory for Food Borne Parasites, 23 Avenue du Général de Gaulle, 94700 Maisons Alfort, France
    Int J Parasitol 40:193-200. 2010
    ..4% (3-7.5%) (45 genotype II; one genotype III). This study offers an accurate drawing of the toxoplasmosis pattern amongst sheep consumed in France and a model for a zoonosis hazard control survey...
  10. ncbi Transmission of small ruminant lentiviruses
    B A Blacklaws
    Department of Clinical Veterinary Medicine, University of Cambridge, Madingley Road, Cambridge CB3 0ES, UK
    Vet Microbiol 101:199-208. 2004
    ..However, such transmission has not been demonstrated to date. The application of control measures based on this information allows more efficient strategies to be developed which will reduce the rate of transmission...
  11. pmc Causes of pneumonia epizootics among bighorn sheep, Western United States, 2008-2010
    Thomas E Besser
    Washington Animal Disease Diagnostic Laboratory, PO Box 647034, Washington State University, Pullman, WA 99164 7034, USA
    Emerg Infect Dis 18:406-14. 2012
    ..These data provide evidence that M. ovipneumoniae plays a primary role in the etiology of epizootic pneumonia of bighorn sheep...
  12. ncbi Genetic characterization of small ruminant lentivirus in Italian mixed flocks: evidence for a novel genotype circulating in a local goat population
    Elena Grego
    Dipartimento di Produzioni Animali, Epidemiologia, Ecologia, Facolta di Medicina Veterinaria, Universita degli Studi di Torino, Via Leonardo da Vinci 44, 10095 Grugliasco TO, Italy
    J Gen Virol 88:3423-7. 2007
    ..A recombinant subunit ELISA, based on genotype E-specific epitopes, was developed and a third independent flock carrying this genotype was identified, based on serology...
  13. ncbi Present situation of cystic echinococcosis in Central Asia
    Paul R Torgerson
    WHO Collaborating Centre for Parasitic Zoonoses, Institute of Parasitology, University of Zurich, Winterthurerstrasse 266a, 8057 Zurich, Switzerland
    Parasitol Int 55:S207-12. 2006
    ..Village and urban dogs have a considerably lower prevalence...
  14. ncbi High prevalence and abundant atypical genotypes of Toxoplasma gondii isolated from lambs destined for human consumption in the USA
    J P Dubey
    United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Beltsville, MD 20705 2350, USA
    Int J Parasitol 38:999-1006. 2008
    ..gondii in lambs, which has important implications in public health. We believe this is the first in-depth genetic analysis of T. gondii isolates from sheep in the USA...
  15. ncbi Bluetongue virus detection by two real-time RT-qPCRs targeting two different genomic segments
    J F Toussaint
    Veterinary and Agrochemical Research Centre, Department of Virology, Groeselenberg 99, B 1180 Brussels, Belgium
    J Virol Methods 140:115-23. 2007
    ..An RT-qPCR amplifying a fragment of the beta-actin mRNA was also developed and validated as internal control for the bluetongue specific assays. The three assays described allow a reliable and rapid detection of BTV...
  16. pmc Molecular characterization and phylogenetic analysis of small ruminant lentiviruses isolated from Canadian sheep and goats
    Yvan L'homme
    Canadian Food Inspection Agency, St Hyacinthe Laboratory, Quebec, Canada
    Virol J 8:271. 2011
    ..There is however no data about the genetic diversity of Caprine Arthritis Encephalitis Virus (CAEV) or Maedi Visna Virus (MVV) in this country...
  17. ncbi Prevention strategies against small ruminant lentiviruses: an update
    Ramses Reina
    Institute of Agrobiotechnology CSIC UPNA Government of Navarra, 31192 Mutilva Baja, Spain
    Vet J 182:31-7. 2009
    ..This review updates the knowledge on diagnosis, risk of infection, immunisation approaches and criteria for selecting the different strategies to control the spread of SRLVs...
  18. ncbi Diagnostic tests for small ruminant lentiviruses
    D de Andres
    Institute of Agrobiotechnology and Natural Resources, Pamplona, Spain
    Vet Microbiol 107:49-62. 2005
    ..Here we review recent developments in laboratory diagnostic methods and their use in field diagnosis. The results suggest that a combination of ELISA and PCR might afford optimal detection of SRLV infection...
  19. ncbi Naming and recognition of six foot lesions of sheep using written and pictorial information: a study of 809 English sheep farmers
    J Kaler
    Ecology and Epidemiology Group, Department of Biological Sciences, University of Warwick, Coventry CV4 7AL, UK
    Prev Vet Med 83:52-64. 2008
    ..Whilst ID and FR were the most prevalent causes of lameness in most flocks it is possible that in up to 17% flocks the primary cause of lameness was a different lesion...
  20. ncbi Phylogenetic analysis and reclassification of caprine and ovine lentiviruses based on 104 new isolates: evidence for regular sheep-to-goat transmission and worldwide propagation through livestock trade
    Cyril Shah
    Swiss National Center for Retroviruses, University of Zurich, Zurich, Switzerland
    Virology 319:12-26. 2004
    ..Furthermore, infection of goats by subtypes A3 or A4 was significantly associated with documented contact with sheep, which also harbor these subtypes, thus indicating regularly occurring sheep-to-goat transmission...
  21. ncbi Toxoplasmosis in sheep--the last 20 years
    J P Dubey
    United States Department of Agriculture, Agricultural Research Service, Animal and Natural Resources Institute, Animal Parasitic Diseases Laboratory, Building 1001, Beltsville, MD 20705 2350, USA
    Vet Parasitol 163:1-14. 2009
    ..In the present paper, information on the prevalence, transmission, and control of ovine toxoplasmosis in the last 20 years is reviewed...
  22. ncbi A microsatellite polymorphism in the gamma interferon gene is associated with resistance to gastrointestinal nematodes in a naturally-parasitized population of Soay sheep
    D W Coltman
    Institute of Cell, Animal and Population Biology, University of Edinburgh, UK
    Parasitology 122:571-82. 2001
    ....
  23. pmc The detection of antibodies against peste des petits ruminants virus in cattle, sheep and goats and the possible implications to rinderpest control programmes
    J Anderson
    ARFC Institute for Animal Health, Pirbright Laboratory, Woking, Surrey, UK
    Epidemiol Infect 112:225-31. 1994
    ....
  24. pmc Molecular epidemiology of Coxiella burnetii from ruminants in Q fever outbreak, the Netherlands
    Hendrik I J Roest
    Central Veterinary Institute, part of Wageningen UR, Lelystad, The Netherlands
    Emerg Infect Dis 17:668-75. 2011
    ..On the basis of 4 loci, this genotype is similar to a human genotype from the Netherlands. This finding strengthens the probability that this genotype of C. burnetii is responsible for the human Q fever epidemic in the Netherlands...
  25. ncbi Incidence and control of brucellosis in the Near East region
    Mohamed Refai
    Department of Microbiology, Faculty of Veterinary Medicine, Cairo University, Giza, Egypt
    Vet Microbiol 90:81-110. 2002
    ..The most commonly used vaccines are B. abortus S19 and B. melitensis Rev.1 vaccines. B. abortus RB51 vaccine is used in some countries on small scale. Vaccination is limited to cattle and small ruminants...
  26. ncbi Ovine progressive pneumonia provirus levels associate with breed and Ovar-DRB1
    Lynn M Herrmann-Hoesing
    US Department of Agriculture, Animal Disease Research Unit, Agricultural Research Service, Pullman, WA 99164 6630, USA
    Immunogenetics 60:749-58. 2008
    ..013-0.043) with higher OPP provirus levels. These results suggest that Ovar-DRB1 contributes as one host genetic factor that controls OPP provirus levels, but does not fully account for the breed-specific OPP proviral differences...
  27. pmc Association of Mycoplasma ovipneumoniae infection with population-limiting respiratory disease in free-ranging Rocky Mountain bighorn sheep (Ovis canadensis canadensis)
    Thomas E Besser
    Washington Animal Disease Diagnostic Laboratory, Washington State University, Pullman, WA 99164 6610, USA
    J Clin Microbiol 46:423-30. 2008
    ..001]). M. ovipneumoniae is strongly associated with bronchopneumonia in free-ranging bighorn sheep and is a candidate primary etiologic agent for this disease...
  28. ncbi A within farm clinical trial to compare two treatments (parenteral antibacterials and hoof trimming) for sheep lame with footrot
    G J Wassink
    Department of Biological Sciences, University of Warwick, Gibbet Hill Rd, Coventry CV4 7AL, West Midlands, UK
    Prev Vet Med 96:93-103. 2010
    ..We conclude that prompt parenteral and topical antibacterial treatment of sheep lame with ID and FR reduced the prevalence and incidence of these infectious conditions and led to improved health, welfare and productivity...
  29. ncbi Anthelmintic resistance
    P J Waller
    CSIRO Division of Animal Production, Pastoral Research Laboratory, Armidale, NSW, Australia
    Vet Parasitol 72:391-405; discussion 405-12. 1997
    ....
  30. ncbi SRLVs: a genetic continuum of lentiviral species in sheep and goats with cumulative evidence of cross species transmission
    Caroline Leroux
    Universite de Lyon, Lyon, France
    Curr HIV Res 8:94-100. 2010
    ..Three classifications have been successively proposed and allowed to refine the SRLV phylogeny over time. Phylogenetic reconstructions support the existence of SRLV cross-species transmission in domestic and wild small ruminants...
  31. pmc Acute phase protein response in an experimental model of ovine caseous lymphadenitis
    Peter D Eckersall
    Division of Animal Production and Public Health, Faculty of Veterinary Medicine, University of Glasgow, Bearsden Rd, Glasgow, G61 1QH, UK
    BMC Vet Res 3:35. 2007
    ..The concentration of Hp in serum increases in experimental CLA but it is not known if SAA and AGP respond in parallel or have differing response profiles...
  32. ncbi First evidence of peste des petits ruminants (PPR) virus circulation in Algeria (Sahrawi territories): outbreak investigation and virus lineage identification
    M de Nardi
    Istituto Zooprofilattico Sperimentale delle Venezie, Legnaro PD, Italy
    Transbound Emerg Dis 59:214-22. 2012
    ..3% of the samples. Sequence analysis revealed that the virus belonged to Lineage IV and phylogenetic analysis indicated a close relationship (99.3%) with the PPRV isolated during the Moroccan outbreak in 2008...
  33. ncbi A survey of the trichostrongylid nematode species present on UK sheep farms and associated anthelmintic control practices
    Charlotte G S Burgess
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik EH26 0PZ, United Kingdom
    Vet Parasitol 189:299-307. 2012
    ..047) and Wales (p(f)=0.012). Farm type, flock type and open or closed status did not have any significant effect on the incidence of anthelmintic resistance when all other factors were taken into consideration...
  34. ncbi Evidence of proviral clearance following postpartum transmission of an ovine lentivirus
    Lynn M Herrmann-Hoesing
    Animal Disease Research Unit, Agricultural Research Service, U S Department of Agriculture, Pullman, WA 99164 6630, USA
    Virology 362:226-34. 2007
    ..These data suggest the clearance of cell-associated lentiviruses from lamb circulation after passive transfer of antibody via colostrum...
  35. ncbi A novel deletion in the LTR region of a Greek small ruminant lentivirus may be associated with low pathogenicity
    K Angelopoulou
    Laboratory of Biochemistry and Toxicology, School of Veterinary Medicine, Aristotle University of Thessaloniki, Thessaloniki 54124, Greece
    Virus Res 118:178-84. 2006
    ..Furthermore, a specific deletion within this region may, at least in part, be associated with low pathogenicity of some SRLV strains...
  36. ncbi Cells, cytokines and other molecules associated with rejection of gastrointestinal nematode parasites
    Els N T Meeusen
    Centre for Animal Biotechnology, School of Veterinary Science, University of Melbourne, Melbourne, VIC 3010, Australia
    Vet Immunol Immunopathol 108:121-5. 2005
    ..In addition, other molecules, in particular carbohydrate binding galectins, may be involved in strengthening the final effector phase of the rejection response...
  37. ncbi Influence of dietary protein supply on resistance to experimental infections with Haemonchus contortus in Ile de France and Santa Ines lambs
    P A Bricarello
    Departamento de Parasitologia, Instituto de Biociencias, Universidade Estadual Paulista, Botucatu, SP, Brazil
    Vet Parasitol 134:99-109. 2005
    ..05). The present results show that the increase in protein content in growing lamb diets may benefit resistance and resilience to gastrointestinal parasites but that these benefits may vary among breeds...
  38. ncbi Divergent ghrelin expression patterns in sheep genetically resistant or susceptible to gastrointestinal nematodes
    Aaron Ingham
    CSIRO Livestock Industries, St Lucia, Queensland, Australia
    Vet Parasitol 181:194-202. 2011
    ..Such differences identify ghrelin as a previously unrecognized factor influencing the acquisition of immunity to nematodes...
  39. ncbi Association between major histocompatibility complex microsatellites, fecal egg count, blood packed cell volume and blood eosinophilia in Pelibuey sheep infected with Haemonchus contortus
    Juan Antonio Figueroa Castillo
    Departamento de Parasitologia, Facultad de Medicina Veterinaria y Zootecnia, Universidad Nacional Autonoma de Mexico, 04510, Mexico, D F, Mexico
    Vet Parasitol 177:339-44. 2011
    ..contortus...
  40. ncbi Farmers' practices and factors associated with the prevalence of all lameness and lameness attributed to interdigital dermatitis and footrot in sheep flocks in England in 2004
    J Kaler
    Department of Biological Sciences, University of Warwick, Coventry, CV4 7AL, UK
    Prev Vet Med 92:52-9. 2009
    ..75; PR=0.71, respectively). We conclude that management factors associated with all lameness, and lameness attributed to ID and FR are similar...
  41. ncbi Use of the Capripoxvirus homologue of Vaccinia virus 30 kDa RNA polymerase subunit (RPO30) gene as a novel diagnostic and genotyping target: development of a classical PCR method to differentiate Goat poxvirus from Sheep poxvirus
    Charles Euloge Lamien
    Animal Production and Health Laboratory, FAO IAEA Agriculture and Biotechnology Laboratory, IAEA Laboratories Seibersdorf, International Atomic Energy Agency, Wagramer Strasse 5, P O Box 100, A1400 Vienna, Austria
    Vet Microbiol 149:30-9. 2011
    ....
  42. ncbi Prevalence and risk factors associated to infection by Toxoplasma gondii in ovine in the State of Alagoas, Brazil
    José Wilton Pinheiro
    Unidade Acadêmica de Garanhuns, Universidade Federal Rural de Pernambuco, Avenida Bom Pastor, S N, 55296 901, Garanhuns, Pernambuco, Brazil
    Parasitol Res 105:709-15. 2009
    ....
  43. ncbi Mycoplasma ovipneumoniae can predispose bighorn sheep to fatal Mannheimia haemolytica pneumonia
    Rohana P Dassanayake
    Department of Veterinary Microbiology and Pathology, Washington State University, Pullman, WA 99164 6610, USA
    Vet Microbiol 145:354-9. 2010
    ..M. haemolytica and M. ovipneumoniae were isolated from the lungs. These results suggest that M. ovipneumoniae alone may not cause fatal pneumonia in BHS, but can predispose them to fatal pneumonia due to M. haemolytica infection...
  44. ncbi Seroprevalence of Toxoplasma gondii in pigs, sheep, goats, and cattle from Grenada and Carriacou, West Indies
    A Chikweto
    Pathobiology Academic Program, School of Veterinary Medicine, St George s University, Grenada, West Indies
    J Parasitol 97:950-1. 2011
    ..gondii. Results indicate that pigs, sheep, and goats could be important sources of T. gondii infection if their meat is consumed undercooked...
  45. ncbi Prevalence and molecular characterization of Cryptosporidium and Giardia species and genotypes in sheep in Maryland
    Monica Santin
    Environmental Microbial Safety Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Building 173, BARC East, 10300 Baltimore Avenue, Beltsville, MD 20705, USA
    Vet Parasitol 146:17-24. 2007
    ..duodenalis Assemblage A suggests a low prevalence of these zoonoses. However, the high prevalence of the zoonotic cervine genotype indicates that sheep should be considered a potential environmental source of this human pathogen...
  46. ncbi The detection of Toxoplasma gondii by comparing cytology, histopathology, bioassay in mice, and the polymerase chain reaction (PCR)
    A v Da Silva
    Departamento de Higiene Veterinária e Saúde Pública, Faculdade de Medicina Veterinaria e Zootecnia, Distrito de Rubião Jr, S N, SP, CEP 18 618 000, Botucatu
    Vet Parasitol 97:191-8. 2001
    ..1%) of the trypsin and 3 (7.7%) of the pepsin-digested samples showed T. gondii DNA. T. gondii isolation rate in mice (n = 34; 85.0%) was significantly higher than detection by PCR (n = 15; 37.5%)...
  47. pmc Mannose receptor may be involved in small ruminant lentivirus pathogenesis
    Helena Crespo
    Institute of Agrobiotechnology, CSIC UPNA Government of Navarra, Ctra Mutilva, Mutilva Baja, 31192, Spain
    Vet Res 43:43. 2012
    ..The increased MR expression appeared to be SRLV specific and may have a role in lentiviral pathogenesis...
  48. ncbi Impact of footrot vaccination and antibiotic therapy on footrot and contagious ovine digital dermatitis
    J S Duncan
    School of Veterinary Science, Faculty of Medical and Veterinary Science, University of Bristol, Langford House, Langford, Bristol BS40 5DU
    Vet Rec 170:462. 2012
    ..83, 95 per cent CI 2.61 to 5.62, P<0.001). These results suggest a role for infection with Dichelobacter nodosus in the aetiopathogenesis of CODD on this farm...
  49. ncbi Genetic variation within Taenia multiceps in Sardinia, Western Mediterranean (Italy)
    A Varcasia
    Sezione di Parassitologia e Malattie Parassitarie, Dipartimento di Biologia Animale, Universita degli Studi di Sassari, 2 07100 Via Vienna, Sassari, Italy
    Parasitol Res 99:622-6. 2006
    ..This is the first description of genetic variability in T. multiceps. Further investigations will be required to understand to what extent the genetic variability described in this paper would be reflected also in phenotypic differences...
  50. ncbi Gastrointestinal nematode species burdens and host mortality in a feral sheep population
    B H Craig
    Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Scotland
    Parasitology 133:485-96. 2006
    ....
  51. ncbi Genetic typing of Echinococcus granulosus in Romania
    J M Bart
    SERF Team Equipe Santé Environment Rural Franche Comté, Parasitology Department, College of Medicine of Besançon, 19 rue Ambroise Paré, 25000 Besancon, France
    Parasitol Res 98:130-7. 2006
    ..To our knowledge, this is the first report which demonstrates the occurrence of the Tasmanian sheep strain in cattle and the sympatric occurrence of these three strains (G1, G2, and G7) in Europe...
  52. pmc Sheep may not be an important zoonotic reservoir for Cryptosporidium and Giardia parasites
    Una M Ryan
    Division of Health Sciences, School of Veterinary and Biomedical Science, Murdoch University, Murdoch, Western Australia, Australia 6150
    Appl Environ Microbiol 71:4992-7. 2005
    ..These results suggest that the public health risk of sheep-derived Cryptosporidium and Giardia spp. in catchment areas and effluent may be overestimated and warrant further investigation...
  53. ncbi Immunohistochemical distinction between preclinical bovine spongiform encephalopathy and scrapie infection in sheep
    C M A Thuring
    Department of Animal Husbandry and Production, Faculty of Veterinary Medicine, University College Dublin, Ballsbridge, Dublin 4, Ireland
    J Comp Pathol 132:59-69. 2005
    ..In contrast, antibodies against epitopes situated N- and C-terminally from the 93-106 region of the ovine prion protein revealed no differences between BSE- and scrapie-infected sheep in terms of PrPSc granules in TBMs...
  54. ncbi Effects of housing on the incidence of visna/maedi virus infection in sheep flocks
    I Leginagoikoa
    Department of Animal Health, NEIKER Instituto Vasco de Investigación y Desarrollo Agrario, Berreaga 1, 48460 Derio, Bizkaia, Spain
    Res Vet Sci 88:415-21. 2010
    ....
  55. ncbi Seroprevalence of Toxoplasma gondii in sheep and goats in Rahim Yar Khan (Punjab), Pakistan
    M Ramzan
    Department of Parasitology, University of Agriculture, Faisalabad, 38040, Pakistan
    Trop Anim Health Prod 41:1225-9. 2009
    ..75; 99% C.I. = 0.47, 6.51) as compared to the group less than one year of age followed by the 2-2.5 years age group (OR = 1.63; 99% C.I. = 0.50, 5.74) whereas group with more than 3 years of age least seropositive...
  56. ncbi Association of CD80 and CD86 expression levels with disease status of Visna/Maedi virus infected sheep
    Ramses Reina
    Instituto de Agrobiotecnología CSIC Universidad Pública de Navarra Gobierno de Navarra, Navarra
    Viral Immunol 20:609-22. 2007
    ....
  57. ncbi Diverse host-virus interactions following caprine arthritis-encephalitis virus infection in sheep and goats
    Antoine Rachid
    Anses, Niort Laboratory, Ruminant Retrovirus Unit, Niort, France
    J Gen Virol 94:634-42. 2013
    ....
  58. ncbi Transitions in immune responses to Mycobacterium paratuberculosis
    J R Stabel
    USDA ARS, National Animal Disease Center, Ames, IA 50010, USA
    Vet Microbiol 77:465-73. 2000
    ..This paper reviews the current knowledge of T cell immune responses in M. paratuberculosis infection based upon clinical studies and research using mouse models...
  59. ncbi Experimental infection of pregnant ewes with bovine viral diarrhea virus type-2 (BVDV-2): effects on the pregnancy and fetus
    C F Scherer
    , Universidade Federal de Santa Maria (UFSM, 97105-900, RS, Santa Maria, Brazil
    Vet Microbiol 79:285-99. 2001
    ..These features make this species an attractive animal model for studying the pathogenesis of congenital BVDV-2 infection...
  60. ncbi Antibodies to surface epitopes of the carbohydrate larval antigen CarLA are associated with passive protection in strongylid nematode challenge infections
    G B L Harrison
    AgResearch Ltd, Hopkirk Research Institute, Grasslands Research Centre, Palmerston North, New Zealand
    Parasite Immunol 30:577-84. 2008
    ..The results provide further evidence that the larval surface carbohydrate antigen CarLA has potential as a mucosal immunogen for a strongylid nematode vaccine...
  61. ncbi Haemonchus contortus and Trichostrongylus colubriformis did not adapt to long-term exposure to sheep that were genetically resistant or susceptible to nematode infections
    K E Kemper
    Victorian Department of Primary Industries, Victorian AgriBiosciences Centre, LaTrobe R and D Park, Bundoora, VIC 3083, Australia
    Int J Parasitol 39:607-14. 2009
    ..In conclusion, selection of sheep for nematode resistance using WEC should be sustainable in the medium to long-term...
  62. pmc Identification of the single base change causing the callipyge muscle hypertrophy phenotype, the only known example of polar overdominance in mammals
    Brad A Freking
    U S Department of Agriculture, Agricultural Research Service, U S Meat Animal Research Center, Clay Center, Nebraska 68933 0166, USA
    Genome Res 12:1496-506. 2002
    ..Initial functional analysis indicates sequence encompassing the mutation is part of a novel transcript expressed in sheep fetal muscle we have named CLPG1...
  63. ncbi Diagnostic performance of ELISA and PCR in identifying SRLV-infected sheep and goats using serum, plasma and milk samples and in early detection of infection in dairy flocks through bulk milk testing
    J M A Brinkhof
    Department for Diagnostics, Research and Epidemiology, Animal Health Service Deventer, Deventer, The Netherlands
    Vet Microbiol 142:193-8. 2010
    ..These results demonstrate the potential of bulk milk testing as a cost effective tool for early detection of infection in dairy flocks, which is essential for SRLV-monitoring programs...
  64. ncbi High mortality and lesions of the central nervous system in trypanosomosis by Trypanosoma vivax in Brazilian hair sheep
    G J N Galiza
    Veterinary Hospital, CSTR, Federal University of Campina Grande, Patos, Paraíba 58700 000, Brazil
    Vet Parasitol 182:359-63. 2011
    ..vivax was introduced to the farm and the susceptible flock by buffalos that were asymptomatic carriers of the infection; T. vivax was most likely transmitted by Tabanus spp. bites and also iatrogenically...
  65. ncbi Toxoplasma gondii in Switzerland: a serosurvey based on meat juice analysis of slaughtered pigs, wild boar, sheep and cattle
    A E Berger-Schoch
    Institute of Parasitology, Vetsuisse Faculty, University of Bern, Bern, Switzerland
    Zoonoses Public Health 58:472-8. 2011
    ..Conclusively, the results demonstrated a high seroprevalence of T. gondii in animals slaughtered for meat production and revealed that increasing age of the animals is a more important risk factor than housing conditions in Switzerland...
  66. ncbi Development of one-step real-time RT-PCR assay for detection and quantitation of peste des petits ruminants virus
    Jingyue Bao
    China Animal Health and Epidemiology Center, Qingdao, Shandong 266032, China
    J Virol Methods 148:232-6. 2008
    ..7% to 73.3% by use of the real-time qRT-PCR. The real-time qRT-PCR assay described in this report allows the rapid, specific and sensitive laboratory detection of PPRV in tissue samples from field cases...
  67. ncbi Evaluation and application of a molecular method to assess the composition of strongylid nematode populations in sheep with naturally acquired infections
    Florian Roeber
    Department of Veterinary Science, The University of Melbourne, 250 Princes Highway, Werribee, Victoria 3030, Australia
    Infect Genet Evol 11:849-54. 2011
    ..This PCR tool has the potential to replace the conventional technique of larval culture. Future efforts will focus on enhancing and adapting this molecular method for high throughput application in routine, diagnostic settings...
  68. ncbi Experimental feed induction of ruminal lactic, propionic, or butyric acidosis in sheep
    A Lettat
    INRA, UR1213 Herbivores, Centre de Recherches de Clermont Ferrand Theix, F 63122 Saint Genes Champanelle, France
    J Anim Sci 88:3041-6. 2010
    ..We developed an original model that promoted differentiated fermentation pathways in the rumen of sheep. It will be used to study the ruminal microbiome changes involved in different acidosis situations...
  69. ncbi Escherichia coli O157:H7 colonization in small domestic ruminants
    Roberto M La Ragione
    Department of Food and Environmental Safety, Veterinary Laboratories Agency, Addlestone, Surrey, UK
    FEMS Microbiol Rev 33:394-410. 2009
    ..This review aims to critically review the current knowledge regarding colonization and persistence of E. coli O157:H7 in small domestic ruminants, including comparisons with the bovine host where appropriate...
  70. ncbi Anthelmintic resistance detection methods
    M A Taylor
    Veterinary Laboratories Agency, Woodham Lane, New Haw, Addlestone, Surrey, KT15 3NB, UK
    Vet Parasitol 103:183-94. 2002
    ..This review covers those tests that have been reported and described and highlights some of their strengths and weaknesses...
  71. ncbi Risk factors for seroprevalence of ovine lentivirus in breeding ewe flocks in Nebraska, USA
    J E Keen
    USDA, ARS, US Meat Animal Research Center, NE 68933, USA
    Prev Vet Med 30:81-94. 1997
    ..These findings support the hypothesis that management control efforts should concentrate on events early in the life of sheep, as this period is associated with factors which can modulate the risk for OLV infection...
  72. ncbi Prevalence and molecular characterisation of Cryptosporidium and Giardia species in pre-weaned sheep in Australia
    Rongchang Yang
    Division of Veterinary and Biomedical Sciences, Murdoch University, Murdoch, Western Australia 6150, Australia
    Vet Parasitol 161:19-24. 2009
    ..The findings of the present study indicate that pre-weaned lambs are not an important source of zoonotic Giardia genotypes in Australia but may be an important source of zoonotic Cryptosporidium...
  73. pmc Direct evidence for natural transmission of small-ruminant lentiviruses of subtype A4 from goats to sheep and vice versa
    Cyril Shah
    Swiss National Center for Retroviruses, University of Zurich, Zurich, Switzerland
    J Virol 78:7518-22. 2004
    ..These findings present for the first time direct evidence that natural interspecies transmission of SRLV is ongoing in both directions. The findings are of relevance to virus eradication programs in both species...
  74. ncbi Efficacy of two cyclooctadepsipeptides, PF1022A and emodepside, against anthelmintic-resistant nematodes in sheep and cattle
    G von Samson-Himmelstjerna
    Institute for Parasitology, Hannover School of Veterinary Medicine, Bunteweg 17, D 30559 Hannover, Germany
    Parasitology 130:343-7. 2005
    ..Both, PF1022A and emodepside were found to be fully effective against these parasite populations. These findings confirm that this new class of compounds acts by a different mode of action compared to the above-mentioned anthelmintics...
  75. pmc Field efficacy and safety of an oral formulation of the novel combination anthelmintic, derquantel-abamectin, in sheep in New Zealand
    P R Little
    Veterinary Medicine Research and Development, Pfizer Animal Health, 45 Poplar Road, Parkville 3052, Australia
    N Z Vet J 58:121-9. 2010
    ..To evaluate the efficacy and safety of the novel anthelmintic combination, derquantel-abamectin, against gastrointestinal nematode populations in sheep, under field-use conditions...
  76. pmc A super-spreading ewe infects hundreds with Q fever at a farmers' market in Germany
    Klaudia Porten
    Robert Koch Institute Seestrasse 10, 13353 Berlin, Germany
    BMC Infect Dis 6:147. 2006
    ..In May 2003 the Soest County Health Department was informed of an unusually large number of patients hospitalized with atypical pneumonia...
  77. ncbi Ecology of the free-living stages of major trichostrongylid parasites of sheep
    Lauren J O'Connor
    Centre for Animal Health and Welfare, School of Rural Science and Agriculture, University of New England, Armidale, NSW 2351, Australia
    Vet Parasitol 142:1-15. 2006
    ..We propose a logical framework for future ecological investigations to overcome some of these problems, facilitate the development of a more integrated dataset on the subject and improve prediction of free-living development...
  78. pmc Disease dynamics over very different time-scales: foot-and-mouth disease and scrapie on the network of livestock movements in the UK
    Rowland R Kao
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    J R Soc Interface 4:907-16. 2007
    ..These contradictory indicators emphasize that appropriate observation time frames and good discrimination among types of potentially infectious contacts are vital in order for network analysis to be a valuable epidemiological tool...
  79. ncbi Q Fever in dairy animals
    Annie Rodolakis
    INRA, UR 1282 Infectiologie Animale et Santé Publique, F 37380 Nouzilly
    Ann N Y Acad Sci 1166:90-3. 2009
    ..The number of Coxiella shed in milk is generally low. The phase I vaccine prevented abortion and greatly decreased the shedding of C. burnetii in milk...
  80. ncbi Spatial risk assessment of Rift Valley fever in Senegal
    Archie C A Clements
    Epidemiology Division, Department of Veterinary Clinical Sciences, Royal Veterinary College, Hatfield, Hertfordshire, United Kingdom
    Vector Borne Zoonotic Dis 7:203-16. 2007
    ..These risk maps are suitable for use in planning improved sentinel surveillance systems in Senegal, although further data collection is required in large areas of Senegal to better define the spatial distribution of RVF...
  81. pmc Global socioeconomic impact of cystic echinococcosis
    Christine M Budke
    University of Zurich, Zurich, Switzerland
    Emerg Infect Dis 12:296-303. 2006
    ..This initial valuation demonstrates the necessity for increased monitoring and global control of CE...
  82. ncbi Isolation and molecular characterization of Toxoplasma gondii strains from different hosts in Iran
    N Zia-Ali
    Department of Medical Parasitology and Mycology, School of Medicine, Kerman University of Medical Sciences, P O Box 444, Kerman, Iran
    Parasitol Res 101:111-5. 2007
    ..The results indicated that the studied isolates consisted of only two genotypes, II and III, with no evidence of type 1 or mixed genotypes...
  83. ncbi Parasite loss and inhibited development of Teladorsagia circumcincta in relation to the kinetics of the local IgA response in sheep
    A M Halliday
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Penicuik, Scotland, UK
    Parasite Immunol 29:425-34. 2007
    ..The timing of the response suggested that it occurred too late to have been the cause of worm loss or arrested development, though it may have retarded the growth of developing parasites...
  84. ncbi IgG-sandwich and IgM-capture enzyme-linked immunosorbent assay for the detection of antibody to Rift Valley fever virus in domestic ruminants
    Janusz T Paweska
    Special Pathogens Unit, National Institute for Communicable Diseases, Private Bag X4, Sandringham 2131, South Africa
    J Virol Methods 113:103-12. 2003
    ..As highly accurate and safe tests, they have the potential to replace traditional diagnostic methods, which pose biohazard risks limiting their use outside of endemic areas to high containment facilities...
  85. ncbi Detection of Mycoplasma ovipneumoniae in Pasteurella-vaccinated sheep flocks with respiratory disease in England
    L McAuliffe
    Mycoplasma Group, Veterinary Laboratories Agency Weybridge, Addlestone, Surrey KT15 3NB
    Vet Rec 153:687-8. 2003
  86. ncbi Melatonin, as an adjuvant-like agent, enhances platelet responsiveness
    Sergio Regodón
    Department of Animal Medicine, University of Extremadura, Caceres, Spain
    J Pineal Res 46:275-85. 2009
    ..These observations suggest that the use of melatonin, as a novel adjuvant, induces beneficial effects on platelet function and haemostasis, and opens new perspectives for therapeutic manipulation of immune responses to vaccination...
  87. ncbi Factors associated with changes of state of foot conformation and lameness in a flock of sheep
    J Kaler
    School of Life Sciences, University of Warwick, Coventry CV4 7AL, UK
    Prev Vet Med 97:237-44. 2010
    ..Treatment of ewes lame with footrot with parenteral antibacterials leads to recovery from lameness and prevents or resolves poor foot conformation which then reduces the susceptibility to further lameness with footrot...
  88. ncbi Identification, genetic diversity and prevalence of Theileria and Babesia species in a sheep population from Northern Spain
    Daniel Nagore
    Department of Animal Health, Instituto Vasco de Investigación y Desarrollo Agrario Berreaga 1, 48160 Derio, Bizkaia, Spain
    Int J Parasitol 34:1059-67. 2004
    ..The widespread distribution of Theileria spp. in the studied sheep population suggests that the parasites involved are of relatively low pathogenicity, in contrast to what has been reported for Theileria sp. China 1 in other countries...
  89. ncbi Risk factors associated with Mycoplasma agalactiae infection of small ruminants in northern Jordan
    Waleed Al-Momani
    University of Nizwa, Barkat Al Mauz, Nizwa, Oman
    Prev Vet Med 83:1-10. 2008
    ..04) with M. agalactiae seropositivity. Educating small ruminant farmers to avoid the use of outsider rams, ensuring adequate cleaning of milking utensils and separating the young from dams would enhance the health of small ruminants...
  90. ncbi Epidemiology of gastrointestinal nematode parasitism in Suffolk and Gulf Coast Native sheep with special emphasis on relative susceptibility to Haemonchus contortus infection
    J E Miller
    Department of Epidemiology and Community Health, School of Veterinary Medicine, Louisiana State University, Baton Rouge 70803, USA
    Vet Parasitol 74:55-74. 1998
    ..contortus) than Suffolk sheep...
  91. pmc Maedi-visna virus and caprine arthritis-encephalitis virus: distinct species or quasispecies and its implications for laboratory diagnosis
    J Pasick
    Canadian Food Inspection Agency, National Centre for Foreign Animal Disease, Winnipeg, Manitoba
    Can J Vet Res 62:241-4. 1998
    ..Implications for diagnostic testing and control of these diseases are discussed...
  92. pmc Seroepidemiological study of Q fever in domestic ruminants in semi-extensive grazing systems
    Francisco Ruiz-Fons
    NEIKER Instituto Vasco de Investigación y Desarrollo Agrario, Department of Animal Health, Bizkaia, Spain
    BMC Vet Res 6:3. 2010
    ..Serum antibodies were analysed by ELISA and positive samples were retested by Complement Fixation test (CFT) to detect recent infections...
  93. ncbi Estimating genetic differences in natural resistance in Rhön and Merinoland sheep following experimental Haemonchus contortus infection
    M Gauly
    Department of Animal Breeding and Genetics, Oberer Hardthof 18, Justus Liebig University of Giessen, D 35398 Giessen, Germany
    Vet Parasitol 106:55-67. 2002
    ..01). IgG was significantly (P<0.05) and positively correlated with worm burden in male Merinoland and IgL with worm burden in male Rhön sheep...
  94. ncbi Transmission and control implications of seroconversion to Maedi-Visna virus in Basque dairy-sheep flocks
    Eduardo Berriatua
    Sanidad Animal, Instituto Vasco de Investigacion y Desarrollo Agrario NEIKER, 48160 Derio, Bizkaia, Spain
    Prev Vet Med 60:265-79. 2003
    ....
  95. ncbi The use of melatonin as a vaccine agent
    Sergio Regodón
    Section of Histology, Department of Veterinary Medicine, The University of Extremadura Veterinary School, Avda de la Universidad, 10071 Caceres, Spain
    Vaccine 23:5321-7. 2005
    ..The finding that melatonin enhances a defined immune response in vivo opens new perspectives for the improvement of Th2-biased immune responses by alum adjuvants...
  96. ncbi The immune response to a DNA vaccine can be modulated by co-delivery of cytokine genes using a DNA prime-protein boost strategy
    J P Scheerlinck
    Cooperative Research Centre for Vaccine Technology Unit, CSIRO Livestock Industries, Private Bag 24, Geelong, Victoria 3220, Australia
    Vaccine 19:4053-60. 2001
    ..This study has demonstrated the efficacy of the co-delivery of cytokines to modulate immune responses generated in a DNA prime-protein boost strategy...
  97. ncbi Real time PCR for the diagnosis of benzimidazole resistance in trichostrongylids of sheep
    M A Alvarez-Sánchez
    Dpt Patología Animal Sanidad Animal, Facultad de Veterinaria, Universidad de Leon, C Profesor Pedro Cármenes s n, 24071 Leon, Spain
    Vet Parasitol 129:291-8. 2005
    ..A sensitive, rapid, highly reproducible and inexpensive technique for detecting resistance to benzimidazoles in a worm population has been developed...
  98. ncbi A bighorn sheep die-off in southern Colorado involving a Pasteurellaceae strain that may have originated from syntopic cattle
    Lisa L Wolfe
    Colorado Division of Wildlife, Wildlife Research Center, 317 West Prospect Road, Fort Collins, Colorado 80526 2097, USA
    J Wildl Dis 46:1262-8. 2010
    ..Our and others' findings suggest that intimate interactions between wild sheep and cattle should be discouraged as part of a comprehensive approach to health management and conservation of North American wild sheep species...
  99. pmc Transcriptomic analysis of the temporal host response to skin infestation with the ectoparasitic mite Psoroptes ovis
    Stewart T G Burgess
    Moredun Research Institute, Pentlands Science Park, Bush Loan, Edinburgh, Midlothian, EH26 0PZ, Scotland, UK
    BMC Genomics 11:624. 2010
    ..The main objective of this study was to perform a combined network and pathway analysis of the in vivo skin response to infestation with P. ovis to gain a clearer understanding of the mechanisms and signalling pathways involved...
  100. ncbi Pheno-genotypic characterisation of Escherichia coli O157:H7 isolates from domestic and wild ruminants
    S Sanchez
    Departamento de Sanidad Animal, Facultad de Veterinaria, Universidad de Extremadura, Caceres, Spain
    Vet Microbiol 142:445-9. 2010
    ..coli O157:H7. The study also highlights the emergence of phenotypic variants of E. coli O157:H7, which may not be identified by routine culture methods or by biochemical tests used to characterise serotype O157:H7...
  101. ncbi The current status of sheep pox disease
    V Bhanuprakash
    Division of Virology, Indian Veterinary Research Institute, Mukteswar, Nainital District, Uttaranchal 263 138, India
    Comp Immunol Microbiol Infect Dis 29:27-60. 2006
    ..This synthesis is to present an up-to-date review of the disease and its control to provide the reader with an overview of the problem...

Research Grants22

  1. Vaccine induced resistance against E. granulosus in dogs
    Wenbao Zhang; Fiscal Year: 2007
    ..granulosus infection by vaccination with the recombinant proteins. We will test humoral and cellular responses generated during vaccination to determine possible correlations of the immune parameters with protection. ..
  2. TRICHINELLOSIS AND REGULATION OF HOST GENE EXPRESSION
    Douglas Jasmer; Fiscal Year: 2001
    ..Understanding these mechanisms may also contribute unique insight on mechanisms of muscle differentiation and cell cycle regulation in mammalian cells. ..
  3. Pathogen Discovery in Chronic Lung Disease by Mass Tag PCR and Microarray
    W Ian Lipkin; Fiscal Year: 2009
    ....
  4. A Staged Strategy for Virus Identification and Discovery
    W Ian Lipkin; Fiscal Year: 2005
    ..Our initial focus will be two chronic diseases where specific viral taxa are associated and potentially implicated in pathogenesis: bronchioalveolar cell carcinoma and amyotrophic lateral sclerosis. ..
  5. MOLECULAR ANALYSIS OF A NEUROTROPIC AGENT--BORNA VIRUS
    WALTER LIPKIN; Fiscal Year: 2002
    ....
  6. Mass Tag PCR Detection of Respiratory Pathogens
    W Ian Lipkin; Fiscal Year: 2004
    ..abstract_text> ..
  7. BORNA DISEASE VIRUS AND NEUROPSYCHIATRIC DISEASE
    WALTER LIPKIN; Fiscal Year: 2002
    ..This study will be the first to collect and process human sera and PBMC samples in clinical laboratories with no history of BDV research and dispense aliquots to a central laboratory for randomized, blinded analysis. ..
  8. A DEVELOPMENTAL MODEL FOR AUTISM BASED ON CNS INFECTION
    WALTER LIPKIN; Fiscal Year: 2004
    ..4) Determine how opoptosis contributes to the neuropathology observed after neonatal infection. (5) Analyze regional changes in neurotransmitter systems following neonatal infection. ..
  9. A Staged Strategy for Virus Identification and Discovery
    WALTER LIPKIN; Fiscal Year: 2004
    ..Consistent with aims proposed in AI51292, our initial clinical application will be to analyze enteroviral serotypes implicated in human disease in North America. ..
  10. Molecular Therapy Core Centers
    Arthur Miller; Fiscal Year: 2008
    ..abstract_text> ..
  11. CONFOCAL MICROSCOPE
    Mark Ackermann; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  12. Genetic Regulation of Postnatal Uterine Morphogenesis and Function
    Thomas Spencer; Fiscal Year: 2008
    ..This research will help determine important genes for reproduction and help to design clinical therapies to prevent, identify and treat reproductive problems in women. [unreadable] [unreadable] [unreadable]..
  13. Progestogen Inhibition of Ovarian Cancer Cell Metastasis
    William Murdoch; Fiscal Year: 2003
    ....
  14. Preterm birth, lung innate immunity, and RSV
    Mark Ackermann; Fiscal Year: 2009
    ..The work is significant because it discovers the underlying basis for RSV susceptibility preterm and mechanistic approaches to enhance innate immunity. ..
  15. MICROARRAY ANALYSIS OF RETINAL DEGENERATION IN MICE
    Caroline Zeiss; Fiscal Year: 2007
    ..Colin Barnstable, Professor of Neurobiology and Ophthalmology, who is an internationally recognized molecular biologist using mouse models of retinal development and degeneration. ..
  16. Spiroplasma 16S rDNA in TSE Brain Tissues
    Frank Bastian; Fiscal Year: 2006
    ..involved. Although the role of Spiroplasma in TSE cannot be determined from these experiments, the presence of this microbe in all cases of TSE and not in controls would provide the basis for developing a test for TSE ..
  17. Alloantigen exposure influences infection threshold
    MARY BURKHARD; Fiscal Year: 2006
    ..Because these therapies would work in a virus non-specific manner, they would have potential use at the population level against multiple virus subtypes. ..
  18. JSRV AND OVINE PULMONARY CARCINOMA
    James DeMartini; Fiscal Year: 2001
    ..All of these techniques have been done by the investigators involved. Similar studies, in some cases without the advantage of the newer techniques, have been used with success in other studies of retroviral-associated neoplasia. ..
  19. Cell-FIV: Mucosal transmission and intervention
    MARY BURKHARD; Fiscal Year: 2005
    ..Vaginal challenge with cell-associated FIV will test the correlates of protection. ..
  20. CELL ASSOCIATED FIV--VAGINAL TRANSMISSION AND PROTECTION
    MARY BURKHARD; Fiscal Year: 2003
    ..Vaginal challenge with cell-associated FIV will test the correlates of protection. ..
  21. MECHANISMS REGULATING UTERINE MORPHOGENESIS
    Thomas Spencer; Fiscal Year: 2004
    ....
  22. Pandemic influenza control at the borders of island countries and in household
    Michael Baker; Fiscal Year: 2008
    ..Findings from the housing cohort would be used to guide advice about reducing influenza transmission in households, particularly in terms of crowding levels and exposure to active and passive smoking. ..