poultry diseases

Summary

Summary: Diseases of birds which are raised as a source of meat or eggs for human consumption and are usually found in barnyards, hatcheries, etc. The concept is differentiated from BIRD DISEASES which is for diseases of birds not considered poultry and usually found in zoos, parks, and the wild.

Top Publications

  1. ncbi Molecular epidemiology of chicken anemia virus in Nigeria
    M F Ducatez
    Institute of Immunology, Laboratoire National de Santé, Luxembourg, Grand Duchy of Luxembourg
    Arch Virol 151:97-111. 2006
  2. pmc Development of a real-time reverse transcriptase PCR assay for type A influenza virus and the avian H5 and H7 hemagglutinin subtypes
    Erica Spackman
    Southeast Poultry Research Laboratory, USDA Agricultural Research Service, Athens, Georgia 30605, USA
    J Clin Microbiol 40:3256-60. 2002
  3. pmc Characterization of chicken spleen transcriptome after infection with Salmonella enterica serovar Enteritidis
    Marta Matulova
    Veterinary Research Institute, Brno, Czech Republic
    PLoS ONE 7:e48101. 2012
  4. ncbi Vaccination with Clostridium perfringens recombinant proteins in combination with Montanide™ ISA 71 VG adjuvant increases protection against experimental necrotic enteritis in commercial broiler chickens
    Seung I Jang
    Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service US Department of Agriculture, Beltsville, MD 20705, USA
    Vaccine 30:5401-6. 2012
  5. pmc Rapid expression of chemokines and proinflammatory cytokines in newly hatched chickens infected with Salmonella enterica serovar typhimurium
    G S K Withanage
    Centre for Veterinary Science, Department of Clinical Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, United Kingdom
    Infect Immun 72:2152-9. 2004
  6. pmc Chicken cells sense influenza A virus infection through MDA5 and CARDIF signaling involving LGP2
    Matthias Liniger
    Institute of Virology and Immunoprophylaxis IVI, Mittelhausern, Switzerland
    J Virol 86:705-17. 2012
  7. pmc Duck egg-drop syndrome caused by BYD virus, a new Tembusu-related flavivirus
    Jingliang Su
    Key Laboratory of Zoonosis of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, China
    PLoS ONE 6:e18106. 2011
  8. pmc Immune response of chicken gut to natural colonization by gut microflora and to Salmonella enterica serovar enteritidis infection
    Magdalena Crhanova
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Infect Immun 79:2755-63. 2011
  9. pmc Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens
    C Loc Carrillo
    Division of Food Sciences, School of Biosciences, Sutton Bonington Campus, University of Nottingham, Loughborough LE12 5RD, United Kingdom
    Appl Environ Microbiol 71:6554-63. 2005
  10. pmc Virulence potential of five major pathogenicity islands (SPI-1 to SPI-5) of Salmonella enterica serovar Enteritidis for chickens
    Ivan Rychlik
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    BMC Microbiol 9:268. 2009

Detail Information

Publications311 found, 100 shown here

  1. ncbi Molecular epidemiology of chicken anemia virus in Nigeria
    M F Ducatez
    Institute of Immunology, Laboratoire National de Santé, Luxembourg, Grand Duchy of Luxembourg
    Arch Virol 151:97-111. 2006
    ..This first molecular epidemiological study of CAV in Africa shows that the Nigerian strains cluster with viruses from very diverse geographic origins and were almost as diverse (4.4%) as all other strains combined (5.8%)...
  2. pmc Development of a real-time reverse transcriptase PCR assay for type A influenza virus and the avian H5 and H7 hemagglutinin subtypes
    Erica Spackman
    Southeast Poultry Research Laboratory, USDA Agricultural Research Service, Athens, Georgia 30605, USA
    J Clin Microbiol 40:3256-60. 2002
    ..The remaining samples were positive with only one detection method. Overall the sensitivity and specificity of the H7- and H5-specific RRT-PCR were similar to those of VI and HI...
  3. pmc Characterization of chicken spleen transcriptome after infection with Salmonella enterica serovar Enteritidis
    Marta Matulova
    Veterinary Research Institute, Brno, Czech Republic
    PLoS ONE 7:e48101. 2012
    ..Expression of AVD, EXFABP, IRG1, AH221, TRAP6, SAA and all immunoglobulin genes can be therefore used for the characterization of the course of S. Enteritidis infection in chickens...
  4. ncbi Vaccination with Clostridium perfringens recombinant proteins in combination with Montanide™ ISA 71 VG adjuvant increases protection against experimental necrotic enteritis in commercial broiler chickens
    Seung I Jang
    Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service US Department of Agriculture, Beltsville, MD 20705, USA
    Vaccine 30:5401-6. 2012
    ..These results suggest that vaccination with clostridial recombinant proteins, particularly NetB toxin or PFO, in combination with ISA 71 VG enhances protective immunity against experimental necrotic enteritis in broiler chickens...
  5. pmc Rapid expression of chemokines and proinflammatory cytokines in newly hatched chickens infected with Salmonella enterica serovar typhimurium
    G S K Withanage
    Centre for Veterinary Science, Department of Clinical Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, United Kingdom
    Infect Immun 72:2152-9. 2004
    ..This is the first description of in vivo expression of chemokines and proinflammatory cytokines in response to oral infection with Salmonella in newly hatched chickens...
  6. pmc Chicken cells sense influenza A virus infection through MDA5 and CARDIF signaling involving LGP2
    Matthias Liniger
    Institute of Virology and Immunoprophylaxis IVI, Mittelhausern, Switzerland
    J Virol 86:705-17. 2012
    ..We finally demonstrate that the chMDA5 signaling pathway is inhibited by the viral nonstructural protein 1. In conclusion, chicken cells, including DF-1 fibroblasts and HD-11 macrophage-like cells, employ chMDA5 for sensing AIV...
  7. pmc Duck egg-drop syndrome caused by BYD virus, a new Tembusu-related flavivirus
    Jingliang Su
    Key Laboratory of Zoonosis of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing, China
    PLoS ONE 6:e18106. 2011
    ..More importantly its public health concerns should also be evaluated, and its epidemiology should be closely watched due to the zoonotic nature of flaviviruses...
  8. pmc Immune response of chicken gut to natural colonization by gut microflora and to Salmonella enterica serovar enteritidis infection
    Magdalena Crhanova
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    Infect Immun 79:2755-63. 2011
    ..Active modification of chicken gut microbiota in the future may accelerate or potentiate the maturation of the gut immune system and increase its resistance to infection with different pathogens...
  9. pmc Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens
    C Loc Carrillo
    Division of Food Sciences, School of Biosciences, Sutton Bonington Campus, University of Nottingham, Loughborough LE12 5RD, United Kingdom
    Appl Environ Microbiol 71:6554-63. 2005
    ..The selection of appropriate phage and their dose optimization are key elements for the success of phage therapy to reduce campylobacters in broiler chickens...
  10. pmc Virulence potential of five major pathogenicity islands (SPI-1 to SPI-5) of Salmonella enterica serovar Enteritidis for chickens
    Ivan Rychlik
    Veterinary Research Institute, Hudcova 70, 621 00 Brno, Czech Republic
    BMC Microbiol 9:268. 2009
    ..e. with the remaining four deleted) and a mutant with all 5 SPIs deleted, and assessed their virulence in one-day-old chickens, together with the innate immune response of this host...
  11. pmc Recombinant Bacillus subtilis expressing the Clostridium perfringens alpha toxoid is a candidate orally delivered vaccine against necrotic enteritis
    Tran H Hoang
    School of Biological Sciences, Royal Holloway, University of London, Egham, Surrey TW20 0EX, United Kingdom
    Infect Immun 76:5257-65. 2008
    ..Existing use of spores as competitive exclusion agents in animal feeds supports their use as a potentially economical and heat-stable vaccine for the poultry industry...
  12. ncbi Vaccination of chickens with Salmonella Pathogenicity Island (SPI) 1 and SPI2 defective mutants of Salmonella enterica serovar Enteritidis
    M Matulova
    Veterinary Research Institute, Brno, Czech Republic
    Vaccine 30:2090-7. 2012
    ....
  13. pmc Chicken cecum immune response to Salmonella enterica serovars of different levels of invasiveness
    Angela Berndt
    Friedrich Loeffler Institute, Institute of Molecular Pathogenesis, Naumburger Str 96a, D 07743 Jena, Germany
    Infect Immun 75:5993-6007. 2007
    ..The data indicate that the capability of Salmonella serovars to enter the cecal mucosa and invade lower regions affects both the level and character of the immune response in tissue...
  14. ncbi Mycoplasma synoviae invades non-phagocytic chicken cells in vitro
    Daliborka Dusanic
    Department of Animal Science, Biotechnical Faculty, University of Ljubljana, Groblje 3, 1230 Domzale, Slovenia
    Vet Microbiol 138:114-9. 2009
    ..2+/-0.3%) similar to that of R(low) (1.1+/-0.1%). This is the first study documenting the invasiveness of M. synoviae strains for non-phagocytic chicken cells...
  15. ncbi Immune-related gene expression in response to H11N9 low pathogenic avian influenza virus infection in chicken and Pekin duck peripheral blood mononuclear cells
    Sean C Adams
    Department of Population Health and Reproduction, University of California, Davis, Davis, CA 95616, USA
    Mol Immunol 46:1744-9. 2009
    ..These results highlight important differences in the host response to AIV of two species thought to be critical in the genesis and maintenance of epidemic strains of AIV...
  16. pmc Pathogenicity and antigenicity of a new variant of Korean nephropathogenic infectious bronchitis virus
    Kang Seuk Choi
    Avian Diseases Division, National Veterinary Research and Quarantine Service, Anyang 430 757, Korea
    J Vet Sci 10:357-9. 2009
    ..This report is the first to document the emergence of a new antigenic variant of nephropathogenic IBV in chicken from Korea...
  17. ncbi Coronavirus avian infectious bronchitis virus
    Dave Cavanagh
    Institute for Animal Health, Compton Laboratory, Compton, Newbury, Berkshire RG20 7NN, United Kingdom
    Vet Res 38:281-97. 2007
    ..Experimental vector IB vaccines and genetically manipulated IBVs--with heterologous spike protein genes--have produced promising results, including in the context of in ovo vaccination...
  18. ncbi An emerging recombinant cluster of nephropathogenic strains of avian infectious bronchitis virus in Korea
    Tae Hyun Lim
    Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, 1 Hwayang dong, Gwangjin gu, Seoul, Republic of Korea
    Infect Genet Evol 11:678-85. 2011
    ..This finding provides important information on IBV evolution and is essential for the effective control of IB in Korea...
  19. ncbi Immunogenicity of a Salmonella Enteritidis mutant as vaccine candidate and its protective efficacy against salmonellosis in chickens
    Rahul M Nandre
    College of Veterinary Medicine, Chonbuk National University, Jeonju 561 756, South Korea
    Vet Immunol Immunopathol 144:299-311. 2011
    ..By the examination of the protection efficacy measured by observations of gross lesions in the organs and bacterial recovery, the candidate can provide an efficient protection upon virulent challenge...
  20. pmc A simple and rapid method for detection of Goose Parvovirus in the field by loop-mediated isothermal amplification
    Jinlong Yang
    Chongqing Academy of Animal Science, Chongqing 402460, Chongqing, China
    Virol J 7:14. 2010
    ..The objective of this study is to develop a loop-mediated isothermal amplification (LAMP) method for the sensitive, rapid, and inexpensive detection of GPV in the field...
  21. ncbi Genetic analysis revealed LX4 genotype strains of avian infectious bronchitis virus became predominant in recent years in Sichuan area, China
    Nian Li Zou
    Key Laboratory of Animal Disease and Human Health of Sichuan Province, College of Veterinary Medicine, Sichuan Agricultural University, Ya an, Sichuan, China
    Virus Genes 41:202-9. 2010
    ....
  22. ncbi Characterization of a novel live attenuated infectious bronchitis virus vaccine candidate derived from a Korean nephropathogenic strain
    Hyun Jeong Lee
    Avian Disease Laboratory, College of Veterinary Medicine, Konkuk University, 1 Hwayang dong, Gwangjin gu, Seoul 143 701, Republic of Korea
    Vaccine 28:2887-94. 2010
    ....
  23. pmc DNA sequence of a ColV plasmid and prevalence of selected plasmid-encoded virulence genes among avian Escherichia coli strains
    Timothy J Johnson
    Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, 1802 Elwood Drive, VMRI 2, Iowa State University, Ames, IA 50011
    J Bacteriol 188:745-58. 2006
    ..coli. The region of pAPEC-O2-ColV containing genes that are highly prevalent among APEC appears to be a distinguishing trait of APEC strains...
  24. pmc Longitudinal study of Finnish Campylobacter jejuni and C. coli isolates from humans, using multilocus sequence typing, including comparison with epidemiological data and isolates from poultry and cattle
    Rauni Kärenlampi
    Department of Food and Environmental Hygiene, Faculty of Veterinary Medicine, P O Box 66, FI 00014 University of Helsinki, Finland
    Appl Environ Microbiol 73:148-55. 2007
    ..In contrast, ST-53, ST-58, ST-61, and ST-883 were significantly associated with isolates from cattle. Further studies are needed to reveal the significance of the observed associations...
  25. pmc Characterization of H9 subtype influenza viruses from the ducks of southern China: a candidate for the next influenza pandemic in humans?
    K S Li
    Joint Influenza Research Centre SUMC and HKU, Department of Microbiology and Immunology, Shantou University Medical College, Shantou, Guangdong 515031, P R China
    J Virol 77:6988-94. 2003
    ..Such reassortants may directly or indirectly play a role in the emergence of the next pandemic virus...
  26. ncbi Avian influenza: recent developments
    Ilaria Capua
    OIE and National Reference Laboratory for Avian Influenza, Istituto Zooprofilattico Sperimentale delle Venezie, Viale dell Universita 10, 35020 Legnaro, Padova, Italy
    Avian Pathol 33:393-404. 2004
    ....
  27. ncbi Increased detection of extended spectrum beta-lactamase producing Salmonella enterica and Escherichia coli isolates from poultry
    Cindy Dierikx
    Department of Bacteriology and TSEs, Central Veterinary Institute of Wageningen UR, Lelystad, The Netherlands
    Vet Microbiol 145:273-8. 2010
    ..The reason for the successful spread of this plasmid type in these species is not yet understood...
  28. ncbi An infectious disease of ducks caused by a newly emerged Tembusu virus strain in mainland China
    Pixi Yan
    Shanghai Veterinary Research Institute, Shanghai, PR China
    Virology 417:1-8. 2011
    ..These results indicate that FX2010 and BYD virus are newly emerged Tembusu virus strains that cause an infectious disease in ducks...
  29. pmc The PA protein directly contributes to the virulence of H5N1 avian influenza viruses in domestic ducks
    Jiasheng Song
    Harbin Veterinary Research Institute, CAAS, Harbin 150001, People s Republic of China
    J Virol 85:2180-8. 2011
    ..Our results provide strong evidence that the polymerase PA subunit is a virulence factor for H5N1 AIVs in ducks...
  30. ncbi Toxoplasma gondii infections in chickens (Gallus domesticus): prevalence, clinical disease, diagnosis and public health significance
    J P Dubey
    Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Agricultural Research Service, United States Department of Agriculture, Beltsville, MD 20705 2350, USA
    Zoonoses Public Health 57:60-73. 2010
    ..A very high prevalence of the parasite was found in chickens raised in backyards (up to 100%) and free-range organic (30-50%) establishments...
  31. ncbi Severe acute respiratory syndrome vaccine development: experiences of vaccination against avian infectious bronchitis coronavirus
    Dave Cavanagh
    Institute for Animal Health, Division of Molecular Biology, Compton Laboratory, Newbury, Berkshire, UK
    Avian Pathol 32:567-82. 2003
    ....
  32. ncbi Poultry coccidiosis: recent advancements in control measures and vaccine development
    Rami A Dalloul
    Animal and Natural Resources Institute, BARC East, Animal Parasitic Diseases Laboratory, USDA ARS, Beltsville, MD 20705, USA
    Expert Rev Vaccines 5:143-63. 2006
    ..This paper aims to review the current progress in understanding the host immune response to Eimeria and discuss current and potential strategies being developed for coccidiosis control in poultry...
  33. pmc The pathogenesis of low pathogenicity H7 avian influenza viruses in chickens, ducks and turkeys
    Erica Spackman
    Southeast Poultry Research Laboratory, USDA ARS, 934 College Station Rd, Athens, GA, 30605, USA
    Virol J 7:331. 2010
    ..In this study twelve H7 LPAI virus isolates from North America were each evaluated for their comparative pathogenesis in chickens, ducks, and turkeys...
  34. ncbi Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens
    Filip Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Trends Microbiol 17:32-6. 2009
    ..Recent research is creating a paradigm shift in our understanding of the pathogenesis of NE and is now providing information that will be necessary to monitor and control the incidence of NE in poultry...
  35. ncbi Antimicrobial resistance in selected bacteria from poultry
    Carlton L Gyles
    Department of Pathobiology, University of Guelph, Guelph, ON, Canada
    Anim Health Res Rev 9:149-58. 2008
    ..Commensal E. coli from poultry have similar patterns of resistance but at lower frequencies. Integron associated resistance occurs commonly in Salmonella and E. coli but has not been detected in Campylobacter...
  36. ncbi Variable protection after vaccination of broiler chickens against necrotic enteritis using supernatants of different Clostridium perfringens strains
    A Lanckriet
    Department of Pathology, Bacteriology and Avian Diseases, Research Group Veterinary Public Health and Zoonoses, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, Merelbeke, Belgium
    Vaccine 28:5920-3. 2010
    ..Our results indicate that the protective characteristics of the supernatants are not solely based on the presence of NetB or alpha toxin...
  37. ncbi Safety and efficacy of a maternal vaccine for the passive protection of broiler chicks against necrotic enteritis
    C F Crouch
    Intervet Schering Plough Animal Health, Walton Manor, Walton, Milton Keynes, UK
    Avian Pathol 39:489-97. 2010
    ..These results indicate that, under commercial conditions, maternal vaccination with Netvax™ can help to control losses related to necrotic enteritis...
  38. ncbi The immunobiology of avian systemic salmonellosis
    Lucy Chappell
    Division of Immunology, Institute for Animal Health, Compton, Newbury, RG20 7NN, UK
    Vet Immunol Immunopathol 128:53-9. 2009
    ..In carrier animals persistence may lead to reproductive tract and egg infection associated with a decline in CD4+ T cell numbers and function associated with the onset of sexual maturity in hens...
  39. pmc The successful experimental induction of necrotic enteritis in chickens by Clostridium perfringens: a critical review
    Bahram Shojadoost
    Department of Pathobiology, University of Guelph, Guelph, Ontario, N1G 2W1, Canada
    Vet Res 43:74. 2012
    ..Also a scoring system is provided to assist decisions on humane euthanasia of sick birds...
  40. ncbi Study on coccidiosis of scavenging indigenous chickens in Central Ethiopia
    H Ashenafi
    Faculty of Veterinary Medicine, Addis Ababa University, Debre Zeit, Ethiopia
    Trop Anim Health Prod 36:693-701. 2004
    ..With increasing demand for poultry products in developing countries, knowledge of production constraints in traditional management practices could help devise control strategies for constraints on backyard poultry production systems...
  41. ncbi Genomic analysis of Eimeria spp. populations in relation to performance levels of broiler chicken farms in Arkansas and North Carolina
    Ryan S Schwarz
    Animal Parasitic Diseases Lab, United States Department of Agriculture, 10300 Baltimore Ave, Beltsville, Maryland 20705, USA
    J Parasitol 95:871-80. 2009
    ..mivati-like, based on homology searches. Our study demonstrated the utility of analyzing multiple genomic loci to assess composition and polymorphisms of Eimeria spp. populations...
  42. pmc Ceftiofur resistance in Salmonella enterica serovar Heidelberg from chicken meat and humans, Canada
    Lucie Dutil
    Public Health Agency of Canada, Saint Hyacinthe, Quebec, Canada
    Emerg Infect Dis 16:48-54. 2010
    ....
  43. ncbi Blackhead disease (histomoniasis) in poultry: a critical review
    L R McDougald
    Department of Poultry Science, University of Georgia, Athens, GA 30602, USA
    Avian Dis 49:462-76. 2005
    ..gallinarum as the source of infection. The lack of suitable treatment drugs or vaccines emphasizes the importance of prevention by worm control and management...
  44. ncbi Prevalence of Eimeria species in broilers with subclinical signs from fifty farms
    X M Sun
    Parasitology Laboratory, College of Veterinary Medicine, China Agricultural University, Beijing 100193, PR China
    Avian Dis 53:301-5. 2009
    ..tenella, E. praecox, E. acervulina, E. maxima, and E mitis are the predominant species in local Shandong province, so an effective coccidiosis vaccine applied in this area should contain at least these five Eimeria species...
  45. ncbi Phage therapy reduces Campylobacter jejuni colonization in broilers
    Jaap A Wagenaar
    Division of Infectious Diseases, Animal Sciences Group, P O Box 65, 8200 AB Lelystad, The Netherlands
    Vet Microbiol 109:275-83. 2005
    ..This again resulted in a significant decrease in Campylobacter colonization. We conclude that phage treatment is a promising alternative for reducing C. jejuni colonization in broilers...
  46. pmc Phylogenetic and biological characterization of Newcastle disease virus isolates from Pakistan
    Taseer Ahmed Khan
    USDA ARS, Southeast Poultry Research Laboratory, 934 College Station Rd, Athens, GA 30605, USA
    J Clin Microbiol 48:1892-4. 2010
    ..A new matrix gene test that detected all isolates was developed. Phylogenetic analysis and pathotyping confirmed that virulent viruses of different genotypes are circulating in Pakistan...
  47. ncbi Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils
    L Timbermont
    Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Merelbeke, Belgium
    Avian Pathol 39:117-21. 2010
    ..These results suggest that butyric acid, medium-chain fatty acids and/or essential oils may contribute to the prevention of necrotic enteritis in broilers...
  48. pmc Incidence and mechanism of ciprofloxacin resistance in Campylobacter spp. isolated from commercial poultry flocks in the United Kingdom before, during, and after fluoroquinolone treatment
    Deborah J Griggs
    Antimicrobial Agents Research Group, Division of Immunity and Infection, The Medical School, University of Birmingham, Birmingham B15 2TT, United Kingdom
    Antimicrob Agents Chemother 49:699-707. 2005
    ..Most ciprofloxacin-resistant isolates had the GyrA substitution Thr-86-->Ile. Resistant isolates were isolated from the feces of some flocks up to the point of slaughter, which may have consequences for public health...
  49. ncbi Dietary supplementation with a probiotic fermented four-herb combination enhances immune activity in broiler chicks and increases survivability against Salmonella Gallinarum in experimentally infected broiler chicks
    Bock Gie Jung
    College of Veterinary Medicine, Chonnam National University, Gwangju, Republic of Korea
    J Vet Med Sci 72:1565-73. 2010
    ....
  50. ncbi Rapid detection of Tembusu virus by reverse-transcription, loop-mediated isothermal amplification (RT-LAMP)
    Y Tang
    Zoology Institute, Agricultural University of Shan Dong province, Shan Dong Province, China
    Transbound Emerg Dis 59:208-13. 2012
    ..In conclusion, RT-LAMP with SYBR Green I dye was shown to be a sensitive, simple assay for the rapid diagnosis of TMUV infection in ducks...
  51. ncbi Diversifying evolution of highly pathogenic H5N1 avian influenza virus in Egypt from 2006 to 2011
    E M Abdelwhab
    Institute of Poultry Diseases, Free University of Berlin, Koenigsweg 63, 14163 Berlin, Germany
    Virus Genes 45:14-23. 2012
    ..Continuous monitoring of the evolving H5N1 virus in Egypt is essential to develop new control campaigns in poultry and human population...
  52. ncbi Analysis of the complete genome of Tembusu virus, a flavivirus isolated from ducks in China
    Y Tang
    Zoology Institute, Agricultural University of Shan Dong province, Shan Dong Province, China
    Transbound Emerg Dis 59:336-43. 2012
    ..These data demonstrate that TMUV is a unique virus among the mosquito-borne flaviviruses and also provide a useful reference for a critically important study to determine why TMUV is a serious pathogen for ducks...
  53. ncbi Newcastle disease in the European Union 2000 to 2009
    Dennis J Alexander
    Virology Department, Animal Health and Veterinary Laboratories Agency Weybridge, Addlestone, Surrey, UK
    Avian Pathol 40:547-58. 2011
    ..Future legislation or recommendations aimed at the control and eradication of ND will need to encompass these three sources of virulent ND viruses...
  54. pmc Fluorescently tagged pUL47 of Marek's disease virus reveals differential tissue expression of the tegument protein in vivo
    Keith W Jarosinski
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA
    J Virol 86:2428-36. 2012
    ....
  55. ncbi Assessment of national strategies for control of high-pathogenicity avian influenza and low-pathogenicity notifiable avian influenza in poultry, with emphasis on vaccines and vaccination
    D E Swayne
    World Organisation for Animal Health OIE, 12 rue de Prony, Paris 75017, France
    Rev Sci Tech 30:839-70. 2011
    ..In countries with enzootic HPAI and LPNAI, development and implementation of exit strategies has been difficult...
  56. ncbi Genomic and antigenic characterization of the newly emerging Chinese duck egg-drop syndrome flavivirus: genomic comparison with Tembusu and Sitiawan viruses
    Peipei Liu
    CAS Key Laboratory of Pathogenic Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing, PR China
    J Gen Virol 93:2158-70. 2012
    ..The significance of these studies is discussed in the context of the emergence, evolution, epidemiology, antigenicity and pathogenicity of the newly emergent DEDSV...
  57. ncbi Prevalence of infectious bronchitis and Newcastle disease virus among domestic and wild birds in H5N1 outbreaks areas
    Zekiba Tarnagda
    Institut de recherche en sciences de la sante, Bobo Dioulasso, Burkina Faso
    J Infect Dev Ctries 5:565-70. 2011
    ..This study aimed to determine the prevalence of avian influenza virus, infectious bronchitis virus, and Newcastle disease virus among domestic and wild birds in highly pathogenic avian influenza (HPAI) H5N1 outbreaks areas...
  58. pmc A wild goose metapneumovirus containing a large attachment glycoprotein is avirulent but immunoprotective in domestic turkeys
    Richard S Bennett
    Department of Veterinary and Biomedical Sciences, University of Minnesota, 1971 Commonwealth Avenue, St Paul, MN 55108, USA
    J Virol 79:14834-42. 2005
    ....
  59. pmc The influence of the cage system and colonisation of Salmonella Enteritidis on the microbial gut flora of laying hens studied by T-RFLP and 454 pyrosequencing
    Steen Nordentoft
    National Veterinary Institute, Technical University of Denmark, Section for Poultry, Fish and Fur Animals, Hangovej 2, DK 8200 Aarhus N, Denmark
    BMC Microbiol 11:187. 2011
    ..The distribution of genera in the microbiota in caecum was furthermore described by next generation sequencing of 16S rDNA libraries...
  60. ncbi Naturally occurring parvoviral infection in Hungarian broiler flocks
    Elena Alina Palade
    Department of Pathology and Forensic Veterinary Medicine, Faculty of Veterinary Science, Szent Istvan University, Budapest, Istvan utca 2, Hungary
    Avian Pathol 40:191-7. 2011
    ....
  61. ncbi Non-commercial poultry industries: surveys of backyard and gamefowl breeder flocks in the United States
    L Garber
    United States Department of Agriculture, Animal and Plant Health Inspection Service, Veterinary Services, Centers for Epidemiology and Animal Health, Fort Collins, CO 80526, USA
    Prev Vet Med 80:120-8. 2007
    ..9 residences per circle had backyard poultry flocks. Gamefowl breeder flocks were larger, used more health care and biosecurity practices, and moved birds more frequently compared to backyard flocks...
  62. ncbi Expression of matrix metalloproteinases during impairment and recovery of the avian growth plate
    H Dan
    Department of Biochemistry and Nutrition, Robert H Smith Faculty of Agriculture, Food and Environment, Hebrew University, Israel
    J Anim Sci 87:3544-55. 2009
    ..Our results strengthen the link between MMP expression and growth-plate impairment, and we suggest that gelatinase activity (MMP-2 and 9) facilitates this process...
  63. ncbi Toxoplasma gondii infection in domestic ducks, free-range and caged chickens in southern China
    C Yan
    Department of Parasitology, College of Veterinary Medicine, South China Agricultural University, 483 Wushan Street, Tianhe District, Guangzhou, Guangdong Province 510642, PR China
    Vet Parasitol 165:337-40. 2009
    ..gondii oocysts because free-range chickens feed from the ground, and suggest that the meat from the domestic poultry may be an important source for human infection by T. gondii in People's Republic of China...
  64. pmc Complete genomic sequence of Chinese virulent duck enteritis virus
    Ying Wu
    Institute of Preventive Veterinary Medicine, Sichuan Agricultural University, Wenjiang, Chengdu City, Sichuan, People s Republic of China
    J Virol 86:5965. 2012
    ..In addition, knowledge of this virus will extend our general knowledge of DEV and will be useful for further studies of the mechanisms of virus replication and pathogenesis...
  65. ncbi Intestinal mucus protects Campylobacter jejuni in the ceca of colonized broiler chickens against the bactericidal effects of medium-chain fatty acids
    D Hermans
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Poult Sci 89:1144-55. 2010
    ....
  66. ncbi Carry-over of thermophilic Campylobacter spp. between sequential and adjacent poultry flocks
    Thomas Alter
    Institute of Food Hygiene, Free University Berlin, Koenigsweg 69, 14163 Berlin, Germany
    Vet Microbiol 147:90-5. 2011
    ..In conclusion, the data demonstrate that the large genetic diversity of Campylobacter must be considered in epidemiological evaluations and microbial risk assessments of Campylobacter in poultry...
  67. ncbi Phylogenetic analysis of infectious bronchitis coronaviruses newly isolated in China, and pathogenicity and evaluation of protection induced by Massachusetts serotype H120 vaccine against QX-like strains
    Chuyang Sun
    Division of Avian Infectious Diseases, National Key Laboratory of Veterinary Biotechnology, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People s Republic of China
    Avian Pathol 40:43-54. 2011
    ....
  68. ncbi Highly pathogenic avian influenza virus H5N1 from Egypt escapes vaccine-induced immunity but confers clinical protection against a heterologous clade 2.2.1 Egyptian isolate
    Christian Grund
    Friedrich Loeffler Institut, Greifswald Insel Riems, Germany
    Vaccine 29:5567-73. 2011
    ..In conclusion, monitoring vaccine-driven evolution of HPAIV H5N1 by surveillance, antigenic characterization, and challenge studies is essential to assess efficacy of AIV vaccination campaigns...
  69. ncbi Current status of vaccines against infectious bursal disease
    Hermann Muller
    Institute for Virology, Faculty of Veterinary Medicine, University of Leipzig, An den Tierkliniken 29, Leipzig, Germany
    Avian Pathol 41:133-9. 2012
    ..Recently, live viral vector vaccines have been licensed in several countries and are reaching the market. Here, the current status of IBD vaccines is discussed...
  70. ncbi Molecular epidemiological surveys of H5 subtype highly pathogenic avian influenza viruses in poultry in China during 2007-2009
    Wen Ming Jiang
    China Animal Health and Epidemiology Center, Qingdao 266032, PR China
    J Gen Virol 91:2491-6. 2010
    ..Viruses within Clade 2.3.2 have been circulating widely in China and caused a new wave of cross-continental spreading from Asia to Europe...
  71. ncbi Prevalence and antimicrobial resistance of Campylobacter isolates in broilers from China
    Xia Chen
    National Reference Laboratory for Veterinary Drug Residue, Key Laboratory of Development and Evaluation of the Chemical and Herbal Drugs for Animal Use, Department of Veterinary Pharmacology and Toxicology, College of Veterinary Medicine, China Agricultural University, Beijing 100193, People s Republic of China
    Vet Microbiol 144:133-9. 2010
    ....
  72. ncbi Coinfection of avian influenza virus (H9N2 subtype) with infectious bronchitis live vaccine
    M Haghighat-Jahromi
    Poultry Research Center, School of Veterinary Medicine, Shiraz University, P O Box 1731, 71345, Shiraz, Iran
    Arch Virol 153:651-5. 2008
    ....
  73. pmc Insertion of a multibasic cleavage motif into the hemagglutinin of a low-pathogenic avian influenza H6N1 virus induces a highly pathogenic phenotype
    Vincent J Munster
    Department of Virology, Erasmus Medical Center, PO Box 2040, Rotterdam, Netherlands
    J Virol 84:7953-60. 2010
    ....
  74. pmc Phylogenetic diversity and genotypical complexity of H9N2 influenza A viruses revealed by genomic sequence analysis
    GuoYing Dong
    Key Laboratory of Animal Ecology and Conservation Biology, National Research Center For Wildlife Born Diseases, Institute of Zoology, Chinese Academy of Sciences, Beijing, China
    PLoS ONE 6:e17212. 2011
    ..We propose a nomenclature system for identifying and unifying all lineages and genotypes of H9N2 influenza viruses in order to facilitate international communication on the evolution, ecology and epidemiology of H9N2 influenza viruses...
  75. pmc Transcriptome analysis of avian pathogenic Escherichia coli O1 in chicken serum reveals adaptive responses to systemic infection
    Ganwu Li
    Department of Veterinary Microbiology and Preventive Medicine, College of Veterinary Medicine, Iowa State University, 1802 University Blvd, Ames, IA 50011, USA
    Infect Immun 79:1951-60. 2011
    ..This genome-wide analysis provides novel insight into processes that are important to the pathogenesis of APEC O1...
  76. ncbi A SitABCD homologue from an avian pathogenic Escherichia coli strain mediates transport of iron and manganese and resistance to hydrogen peroxide
    Mourad Sabri
    Institut National de la Recherche Scientifique, INRS Institut Armand Frappier, 531 Boul des Prairies, Laval, Quebec, Canada H7V 1B7
    Microbiology 152:745-58. 2006
    ..coli SitABCD represents a manganese and iron transporter that, in combination with other ion transport systems, may contribute to acquisition of iron and manganese, and resistance to oxidative stress...
  77. ncbi Rapid detection of virulence-associated genes in avian pathogenic Escherichia coli by multiplex polymerase chain reaction
    Christa Ewers
    Institut für Mikrobiologie und Tierseuchen, Freie Universitat Berlin, Philippstrasse 13, 10115 Berlin, Germany
    Avian Dis 49:269-73. 2005
    ..coli and differentiate them from nonpathogenic strains and those belonging to other pathotypes...
  78. pmc First report of Toxoplasma gondii infection in market-sold adult chickens, ducks and pigeons in northwest China
    Wei Cong
    State Key Laboratory of Veterinary Etiological Biology, Key Laboratory of Veterinary Parasitology of Gansu Province, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, Gansu Province, People s Republic of China
    Parasit Vectors 5:110. 2012
    ..gondii infection in domestic birds in Lanzhou, northwest China was available. Therefore, this study was performed to determine the seroprevalence of T. gondii infection in domestic birds in Lanzhou, northwest China...
  79. pmc Quantification of the effect of vaccination on transmission of avian influenza (H7N7) in chickens
    J A van der Goot
    Central Institute for Animal Disease Control Lelystad, The Netherlands
    Proc Natl Acad Sci U S A 102:18141-6. 2005
    ..We discuss the implications of these findings for the use of vaccination programs in poultry and the value of transmission experiments in the process of choosing vaccine...
  80. ncbi Nitric oxide inhibition after Toxoplasma gondii infection of chicken macrophage cell lines
    L V C Guillermo
    Laboratorio de Biologia Celular e Tecidual, Centro de Biociencias e Biotecnologia, Universidade Estadual do Norte Fluminense, Avenida Alberto Lamego 2000, 28013 600, Campos dos Goytacazes, RJ, Brazil
    Poult Sci 83:776-82. 2004
    ..These results demonstrate that in chicken macrophages T. gondii can also inhibit NO production, which suggests that an iNOS suppression mechanism might be used for better survival in macrophages...
  81. ncbi Advances in avian immunology--prospects for disease control: a review
    Pete Kaiser
    The Roslin Institute and R D SVS, University of Edinburgh, Easter Bush Veterinary Centre, Roslin, Midlothian, UK
    Avian Pathol 39:309-24. 2010
    ....
  82. ncbi Comparison of virulence factors and expression of specific genes between uropathogenic Escherichia coli and avian pathogenic E. coli in a murine urinary tract infection model and a chicken challenge model
    Lixiang Zhao
    Animal Infectious Disease Laboratory, College of Veterinary Medicine, Yangzhou University, Yangzhou, Jiangsu 225009, PR China
    Microbiology 155:1634-44. 2009
    ..Further, this study compared the transcriptional profile of virulence genes among APEC and UPEC in vivo...
  83. pmc Surveillance of influenza A virus in migratory waterfowl in northern Europe
    Anders Wallensten
    Smedby Health Center, Kalmar, Sweden
    Emerg Infect Dis 13:404-11. 2007
    ..We argue that wild bird screening can function as a sentinel system, and we give an example of how it could have been used to forecast a remote and deadly outbreak of influenza A in poultry...
  84. ncbi Clostridium perfringens in poultry: an emerging threat for animal and public health
    Filip Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, B 9820 Merelbeke, Belgium
    Avian Pathol 33:537-49. 2004
    ..The most cost-effective control will probably be achieved by balancing the composition of the feed...
  85. ncbi Colonization strategy of Campylobacter jejuni results in persistent infection of the chicken gut
    Kim Van Deun
    Department of Pathology, Bacteriology and Avian Diseases, Ghent University, Salisburylaan 133, Merelbeke, Belgium
    Vet Microbiol 130:285-97. 2008
    ..These findings suggest a novel colonization mechanism by escaping rapid mucosal clearance through short-term epithelial invasion and evasion, combined with fast replication in the mucus...
  86. pmc Characterization of the contribution to virulence of three large plasmids of avian pathogenic Escherichia coli chi7122 (O78:K80:H9)
    Melha Mellata
    The Biodesign Institute, Arizona State University, Tempe, Arizona 85287, USA
    Infect Immun 78:1528-41. 2010
    ..This study should help us understand the virulence of other ExPEC strains and design more efficient infection control strategies...
  87. pmc Recombinant attenuated Salmonella enterica serovar typhimurium expressing the carboxy-terminal domain of alpha toxin from Clostridium perfringens induces protective responses against necrotic enteritis in chickens
    Bereket Zekarias
    The Biodesign Institute, Center for Infectious Diseases and Vaccinology, Arizona State University, 1001 S McAllister, Tempe, AZ 85287 5401, USA
    Clin Vaccine Immunol 15:805-16. 2008
    ..RASV-immunized chickens had reduced intestinal mucosal pathology after challenge with virulent C. perfringens. These results indicate that oral RASV expressing an alpha toxin C-terminal peptide induces protective immunity against NE...
  88. ncbi The paternal effect of Campylobacter jejuni colonization in ceca in broilers
    X Li
    Department of Poultry Science, Texas A and M University, College Station 77843, USA
    Poult Sci 87:1742-7. 2008
    ..jejuni counts in cloacal swabs and those in cecal contents. The results indicated that a paternal effect might be one of the important genetic factors influencing resistance to C. jejuni colonization in broilers...
  89. pmc The dioxin crisis as experiment to determine poultry-related campylobacter enteritis
    Akke Vellinga
    Department of Epidemiology and Social Medicine, Institute of Public Health Louis Pasteur, Brussels, Belgium
    Emerg Infect Dis 8:19-22. 2002
    ..The use of a disaster as an epidemiologic tool offers a unique opportunity to observe exceptional changes in the occurrence of infections or other diseases...
  90. ncbi Chicken anemia virus induced apoptosis: underlying molecular mechanisms
    Mathieu H M Noteborn
    Department of Molecular Cell Biology, Leadd BV and LUMC, Leiden, The Netherlands
    Vet Microbiol 98:89-94. 2004
    ..A number of novel proteins were shown to interact with apoptin in transformed cells. Future studies of apoptin, VP2 and related cellular proteins in chicken cells will unravel the regulatory aspects of CAV-induced apoptosis...
  91. pmc Increased expression of cysteine cathepsins in ovarian tissue from chickens with ovarian cancer
    Suzie E Ahn
    WCU Biomodulation Major, Department of Agricultural Biotechnology, Seoul National University, 599 Gwanak Ro, Gwanak Gu, Seoul 151 921, Korea
    Reprod Biol Endocrinol 8:100. 2010
    ..Chickens spontaneously develop epithelial ovarian cancer and are therefore a good animal model for human ovarian cancer. However, no studies have investigated the expression of CTSs in chickens with ovarian cancer...
  92. ncbi Changes in immune-related gene expression and intestinal lymphocyte subpopulations following Eimeria maxima infection of chickens
    Yeong Ho Hong
    Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, Building 1040, BARC East, United States Department of Agriculture, Beltsville, MD 20705, USA
    Vet Immunol Immunopathol 114:259-72. 2006
    ..Taken together, these data indicate a global chicken intestinal immune response is produced following experimental Eimeria infection involving multiple cytokines, chemokines, and T cell subsets...
  93. pmc The type VI secretion system plays a role in type 1 fimbria expression and pathogenesis of an avian pathogenic Escherichia coli strain
    Fernanda de Pace
    Department of Genetics, Evolution, and Bioagents, Campinas State University Unicamp, Campinas, Sao Paulo, Brazil
    Infect Immun 78:4990-8. 2010
    ..These results suggest that the T6SS influences the expression of type 1 fimbriae and contributes to APEC pathogenesis...
  94. pmc Identification of minimal predictors of avian pathogenic Escherichia coli virulence for use as a rapid diagnostic tool
    Timothy J Johnson
    Department of Veterinary and Biomedical Sciences, University of Minnesota, St Paul, Minnesota 55108, USA
    J Clin Microbiol 46:3987-96. 2008
    ..This panel may be helpful toward clarifying potential roles of APEC in human disease, ascertaining the source of APEC in animal outbreaks, and identifying effective targets of avian colibacillosis control...
  95. ncbi Chicken anemia virus
    K A Schat
    Department of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY 14853, USA
    Curr Top Microbiol Immunol 331:151-83. 2009
    ..Clinical disease is associated with infection in newly hatched chicks lacking maternal antibodies or older chickens with a compromised humoral immune response...
  96. pmc Isolation and molecular characterization of nalidixic acid-resistant extraintestinal pathogenic Escherichia coli from retail chicken products
    James R Johnson
    Department of Medicine, University of Minnesota, Minneapolis, Minnesota 55417, USA
    Antimicrob Agents Chemother 47:2161-8. 2003
    ....
  97. pmc Rescue of very virulent and mosaic infectious bursal disease virus from cloned cDNA: VP2 is not the sole determinant of the very virulent phenotype
    H J Boot
    Department of Avian Virology, Institute for Animal Science and Health, Lelystad, The Netherlands
    J Virol 74:6701-11. 2000
    ..However, the very virulent phenotype was not solely determined by this protein, since mosaic virus containing VP2 of vvIBDV induced neither morbidity nor mortality in young chickens...
  98. pmc Medium-chain fatty acids decrease colonization and invasion through hilA suppression shortly after infection of chickens with Salmonella enterica serovar Enteritidis
    F Van Immerseel
    Department of Pathology, Bacteriology and Avian Diseases, Faculty of Veterinary Medicine, Ghent University, B 9820 Merelbeke, Belgium
    Appl Environ Microbiol 70:3582-7. 2004
    ..Thus, MCFA are potentially useful products for reducing the level of colonization of chicks and could ultimately aid in the reduction of the number of contaminated eggs in the food supply...
  99. ncbi Analysis of chicken cytokine and chemokine gene expression following Eimeria acervulina and Eimeria tenella infections
    Yeong Ho Hong
    Animal Parasitic Diseases Laboratory, Animal and Natural Resources Institute, United States Department of Agriculture, Building 1040, BARC East, Beltsville, MD 20705, USA
    Vet Immunol Immunopathol 114:209-23. 2006
    ..tenella infection. We conclude that coccidiosis induces a diverse and robust primary cytokine/chemokine response, but a more subdued secondary response...
  100. pmc Polyclonal antibody against the DPV UL46M protein can be a diagnostic candidate
    Liting Lu
    Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, YA, AN, Sichuan, China
    Virol J 7:83. 2010
    ..Subsequently, we established Dot-ELISA using the polyclonal antibody and applied it to DPV detection...
  101. pmc Expression and intracellular localization of duck enteritis virus pUL38 protein
    Jun Xiang
    Avian Diseases Research Center, College of Veterinary Medicine of Sichuan Agricultural University, Yaan, Sichuan, China
    Virol J 7:162. 2010
    ..Furthermore, pUL38 was found in purified virus. These results provide the first evidence of the kinetics of expression and intracellular localization of DEV pUL38...

Research Grants26

  1. Pulmonary Arterial Hypertension: Avian Model of Complex Vascular Lesion Developme
    ROBERT WIDEMAN; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  2. CHAGAS DISEASE: AUTOIMMUNITY STEMS FROM PARASITE INVASION OF HOST GENOME
    Antonio Teixeira; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  3. Regulation of T Cell Homeostasis
    Jianzhu Chen; Fiscal Year: 2006
    ..In addition, the role of cell division in facilitating changes in chromatin structure at the IFN-g locus will be investigated by measuring the extent of DNA methylation, histone acetylation and factor binding...
  4. A NOVEL VECTOR FOR VACCINATION AGAINST HEPETITIS C VIRUS
    Nikolaus Osterrieder; Fiscal Year: 2006
    ..The tests will include ELISPOT and CTL assays in the context of a human class I allele using HLA-A2.1 transgenic mice. ..
  5. Development and Maintenance of Memory CD8 T Cells
    Jianzhu Chen; Fiscal Year: 2010
    ....
  6. Cancer and Non-cancer Mortality in Meat Workers (1 RO1-OH 008687-01 A1 SOH)
    Eric Johnson; Fiscal Year: 2008
    ..Infectious disease is a NIOSH priority area. [unreadable] [unreadable] [unreadable]..
  7. MHC Loci in the Control of Marek's Lymphoma
    MARCIA MILLER; Fiscal Year: 2005
    ..abstract_text> ..
  8. Human Metapneumovirus in High Risk Populations
    Gregory Gray; Fiscal Year: 2005
    ..These data will facilitate the development of more comprehensive epidemiological studies, and guide future intervention studies in reducing HMPV morbidity. ..
  9. COMBINATION CHEMOTHERAPY FOR PANDEMIC INFLUENZA
    Robert Webster; Fiscal Year: 2005
    ....
  10. Avian Influenza Vaccines for Pandemic Preparedness
    Daniel Perez; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  11. Transmissibility of Influenza A Viruses
    Daniel Perez; Fiscal Year: 2006
    ..The techniques needed to obtain this information are now available, and the results will lay the groundwork for important changes in agricultural policies and pandemic planning. ..
  12. Mechanisms of Influenza a Virus Transmission in Ferretts
    Daniel Perez; Fiscal Year: 2008
    ....
  13. Development and evaluation of subunit vaccine CmeC against Campylobacter jejuni
    Jun Lin; Fiscal Year: 2008
    ..S. The proposed research will provide novel information on the development of effective vaccine against C. jejuni to protect public health. [unreadable] [unreadable] [unreadable]..
  14. Host range restriction of human influenza viruses
    Christopher Olsen; Fiscal Year: 2009
    ..abstract_text> ..
  15. Mechanisms of T Cell Tumorigenesis
    Jianzhu Chen; Fiscal Year: 2008
    ..Findings from the proposed studies may shed light on the etiology and mechanisms underlying the frequent translocations of the antigen receptor loci in lymphoid tumors in humans. [unreadable] [unreadable] [unreadable]..
  16. MICROARRAY ANALYSIS OF RETINAL DEGENERATION IN MICE
    Caroline Zeiss; Fiscal Year: 2007
    ..Colin Barnstable, Professor of Neurobiology and Ophthalmology, who is an internationally recognized molecular biologist using mouse models of retinal development and degeneration. ..
  17. TRANSGENIC MOUSE MODEL FOR ANALYZING T CELL RESPONSES
    Jianzhu Chen; Fiscal Year: 2002
    ....
  18. Transgenic chickens for protein production
    Robert Etches; Fiscal Year: 2004
    ..These attributes make chickens an attractive option for the large-scale production of therapeutic proteins such as monoclonal antibodies. ..
  19. VZV BACs: New Tools for Pathogenesis Research
    Nikolaus Osterrieder; Fiscal Year: 2005
    ..B-scid/beige mice, and infected MeWo or MeWo-9 cells will be used to inoculate the grafts. Virus replication in the implants will be examined by virus titrations, real-time PCR, histopathology and immunohistochemistry. ..
  20. Resistant E.coli in Humans and Poultry
    James Johnson; Fiscal Year: 2005
    ..Does the research address a current and compelling problem of antimicrobial resistance that is of high public health importance and for which research is needed? [yes]. ..
  21. Population-based Surveillance for Zoonotic Influenza A
    Gregory Gray; Fiscal Year: 2005
    ..We are particularly well suited to conduct this work as we have extensive experience conducting both epidemiological and laboratory-based studies of respiratory pathogens. ..
  22. RNA Interference of Influenza Virus Infection
    Jianzhu Chen; Fiscal Year: 2006
    ..Theoretically, an siRNA-based treatment should remain effective even with the emergence of new strains of the virus. ..
  23. Control of V(D)J Recombination at the TCR beta Locus
    Jianzhu Chen; Fiscal Year: 2007
    ..The proposed studies may help elucidate the role of enhancers in regulating DSB repair, V(D)J recombination, genome instability, and tumorigenesis. ..
  24. POSSIBLE OF ROLE OF AVIAN RETROVIRUSES IN HUMAN CANCER
    Eric Johnson; Fiscal Year: 2002
    ..The confirmed demonstration of ALSV pro-viral DNA in the genome of exposed tumor samples but not in that of control tumor samples, will provide definitive evidence incriminating ALSV in human carcinogenesis. ..