Genomes and Genes
Summary: A condition of fetal overgrowth leading to a large-for-gestational-age FETUS. It is defined as BIRTH WEIGHT greater than 4,000 grams or above the 90th percentile for population and sex-specific growth curves. It is commonly seen in GESTATIONAL DIABETES; PROLONGED PREGNANCY; and pregnancies complicated by pre-existing diabetes mellitus.
Publications241 found, 100 shown here
- [Fetal macrosomia: management, obstetrical and neonatal results. Multicenter case-control study in 15 maternity hospitals in Paris and the Ile de France area]A Batallan
Service de gynécologie obstétrique du professeur P Madelenat, centre hospitalier Bichat Claude Bernard AP HP, rue Henri Huchard, 75018 Paris, France
Gynecol Obstet Fertil 30:483-91. 2002To study the perinatal management of fetal macrosomia (FM) and the obstetrical and neonatal results related to FM in the Ile de France area.
- The influence of obesity and diabetes on the prevalence of macrosomiaHugh M Ehrenberg
Case Western Reserve University School of Medicine, Department of Reproductive Biology, MetroHealth Medical Center, Cleveland, Ohio, USA
Am J Obstet Gynecol 191:964-8. 2004..This study was undertaken to determine the relative contribution of abnormal pregravid maternal body habitus and diabetes on the prevalence of large-for-gestational-age infants...
- Outcome of second delivery after prior macrosomic infant in women with normal glucose toleranceRhona Mahony
Departments of Obstetrics and Gynecology, National Maternity Hospital and University College Dublin, Ireland
Obstet Gynecol 107:857-62. 2006..Our aim was to estimate the obstetric outcome of second delivery in women with normal glucose tolerance whose first fetus was macrosomic (fetal weight >/= 4,500 g)...
- Metabolic syndrome in childhood: association with birth weight, maternal obesity, and gestational diabetes mellitusCharlotte M Boney
Division of Pediatric Endocrinology and Metabolism, Department of Pediatrics, Brown Medical School and Hasbro Children s Hospital, Providence, Rhode Island, USA
Pediatrics 115:e290-6. 2005..We examined the development of MS among large-for-gestational-age (LGA) and appropriate-for-gestational age (AGA) children...
- Risk factors and obstetric complications associated with macrosomiaN E Stotland
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, CA, USA
Int J Gynaecol Obstet 87:220-6. 2004..Macrosomia is associated with adverse maternal outcomes. The objective of this study was to characterize the epidemiology of macrosomia and related maternal complications...
- The macrosomic fetus: a challenge in current obstetricsTore Henriksen
Department of Obstetrics and Gynecology, Rikshospitalet, University of Oslo, Oslo, Norway
Acta Obstet Gynecol Scand 87:134-45. 2008..There is ample evidence that fetal macrosomia is associated with increased risk of complications both for the mother and the newborn...
- A multicenter, randomized trial of treatment for mild gestational diabetesMark B Landon
Department of Obstetrics and Gynecology, Ohio State University, Columbus, USA
N Engl J Med 361:1339-48. 2009..It is uncertain whether treatment of mild gestational diabetes mellitus improves pregnancy outcomes...
- Modifiable determinants of fetal macrosomia: role of lifestyle-related factorsNanna Voldner
Department of Obstetrics and Gynecology, University of Oslo, Rikshospitalet Medical Centre, Oslo, Norway
Acta Obstet Gynecol Scand 87:423-9. 2008..present investigation was to evaluate prospectively the contributions of modifiable maternal predictors of fetal macrosomia (> or =4,200 g), which included lifestyle-related factors, such as nutritional intake, physical activity, ..
- Effect of treatment of gestational diabetes mellitus on pregnancy outcomesCaroline A Crowther
Department of Obstetrics and Gynaecology, University of Adelaide, Adelaide, Australia
N Engl J Med 352:2477-86. 2005..We conducted a randomized clinical trial to determine whether treatment of women with gestational diabetes mellitus reduced the risk of perinatal complications...
- A systematic review of outcomes of maternal weight gain according to the Institute of Medicine recommendations: birthweight, fetal growth, and postpartum weight retentionAnna Maria Siega-Riz
Department of Epidemiology, School of Public Health, University of North Carolina, Chapel Hill, NC, USA
Am J Obstet Gynecol 201:339.e1-14. 2009..Improvements in future research include the use of consistent definitions of gestational weight gain and outcomes of interest, assessment of confounders, and better collection of weight and weight gain data...
- How big is too big? The perinatal consequences of fetal macrosomiaXun Zhang
Department of Pediatrics, McGill University Faculty of Medicine, Montreal, QC, Canada
Am J Obstet Gynecol 198:517.e1-6. 2008....
- Gestational weight gain and gestational diabetes mellitus: perinatal outcomesYvonne W Cheng
Division of Maternal Fetal Medicine, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, California 94143 0132, USA
Obstet Gynecol 112:1015-22. 2008..To examine the association between gestational weight gain and perinatal outcome in women with gestational diabetes mellitus (GDM)...
- Birth complications, overweight, and physical inactivityNanna Voldner
Department of Obstetrics and Gynecology, Rikshospitalet University Hospital, University of Oslo, Oslo, Norway
Acta Obstet Gynecol Scand 88:550-5. 2009..Maternal lifestyle factors are potential predictors of pregnancy complications. We examined relations between modifiable factors and delivery complications...
- Modulation of adipokines and cytokines in gestational diabetes and macrosomiaJ M Ategbo
Department of Physiology, Faculty of Life Sciences, University of Burgundy, 6 Boulevard Gabriel, Dijon 21000, France
J Clin Endocrinol Metab 91:4137-43. 2006..The purpose of this study was to assess the profile of these hormones and cytokines in macrosomic babies, born to gestational diabetic women...
- Fetal macrosomia in pregnant women with gestational diabetesJadranko Segregur
Department of Gynecology and Obstetrics, General Hospital Virovitica, Virovitica, Croatia
Coll Antropol 33:1121-7. 2009The aim of the study was to determine the frequency of fetal macrosomia in newborns from mothers with gestational diabetes mellitus (GDM) and healthy mothers, as well as determining the influence of fetal growth on pregnancy termination, ..
- A randomised control trial of low glycaemic index carbohydrate diet versus no dietary intervention in the prevention of recurrence of macrosomiaJennifer Walsh
Department of Obstetrics and Gynaecology, University College Dublin National Maternity Hospital, Dublin, Ireland
BMC Pregnancy Childbirth 10:16. 2010..b>Fetal macrosomia is associated with an increase in both adverse obstetric and neonatal outcome, and also confers a future risk ..
- Severe obesity, gestational weight gain, and adverse birth outcomesLisa M Bodnar
Department of Epidemiology, University of Pittsburgh, PA 15261, USA
Am J Clin Nutr 91:1642-8. 2010..Therefore, the committee recommended a single range, 5-9 kg at term, for all obese women...
- Risk factors for postpartum hemorrhage in vaginal deliveries in a Latin-American populationClaudio G Sosa
Perinatal Research Unit, School of Medicine, University of Uruguay, Montevideo, Uruguay
Obstet Gynecol 113:1313-9. 2009..To identify risk factors for immediate postpartum hemorrhage after vaginal delivery in a South American population...
- Gestational weight gain in obese mothers and associations with fetal growthStefanie N Hinkle
Emory University, Atlanta, GA, USA
Am J Clin Nutr 92:644-51. 2010..In 2009, the Institute of Medicine recommended gestational weight gains (GWGs) of 5-9 kg for all obese women. Recommendations by severity of obesity were not specified because of a lack of available data...
- Obstetric and neonatal outcome of babies weighing more than 4.5 kg: an analysis by parityE V Mocanu
Coombe Women s Hospital, 8, Dublin, Ireland
Eur J Obstet Gynecol Reprod Biol 92:229-33. 2000..To analyse by parity the obstetric and neonatal outcome of babies delivered weighing more than 4.5 kg...
- Association between regular exercise and excessive newborn birth weightKatrine Mari Owe
Department of Sport Medicine, Norwegian School of Sport Sciences, Oslo, Norway
Obstet Gynecol 114:770-6. 2009..To estimate the association between regular exercise before and during pregnancy and excessive newborn birth weight...
- Evaluating the therapeutic approach in pregnancies complicated by borderline glucose intolerance: a randomized clinical trialM Bonomo
Department of Obstetrics and Gynaecology, Niguarda Ca Granda Hospital, Piazza Ospedale Maggiore 3, 201621 Milan, Italy
Diabet Med 22:1536-41. 2005....
- Trends in fetal growth among singleton gestations in the United States and Canada, 1985 through 1998Cande V Ananth
Department of Obstetrics, Gynecology and Reproductive Sciences, UMDNJ Robert Wood Johnson Medical School, New Brunswick 08901, USA
Semin Perinatol 26:260-7. 2002..These findings suggest that US and Canadian babies are getting bigger. The role of preterm obstetrical induction and preterm cesarean delivery are likely to have influenced these trends...
- Neonatal macrosomia is an independent risk factor for adult metabolic syndromeGregory M Hermann
Department of Pediatrics, University of Iowa, Carver College of Medicine, Iowa City, Iowa 52242, USA
Neonatology 98:238-44. 2010..Weight in infancy correlates with risk of type 2 diabetes, hypertension, and obesity in adulthood. Clinical observations have been confounded by obesity-prone genotypes and obesity-linked lifestyles...
- Risk factors for macrosomia and its clinical consequences: a study of 350,311 pregnanciesMatthew C Jolly
Section of Endocrinology and Metabolic Medicine, The Mint Wing, Imperial College of Science Technology and Medicine, St Mary s Campus, London W2 1PG, UK
Eur J Obstet Gynecol Reprod Biol 111:9-14. 2003..To identify demographic risk factors for either birthweight >4kg or over the 90th centile and to quantify the obstetric risks...
- Being too large for gestational age precedes childhood obesity in African AmericansShobha H Mehta
Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, MI, USA
Am J Obstet Gynecol 204:265.e1-5. 2011..The purpose of this study was to investigate the association between large-for-gestational-age (LGA) infants and the development of childhood obesity in an inner-city primarily African American population...
- Maternal and neonatal outcomes among obese women with weight gain below the new Institute of Medicine recommendationsMarie Blomberg
Division of Obstetrics and Gynecology, Department of Clinical and Experimental Medicine, Faculty of Health Sciences, University of Linkoping, Linkoping, Sweden
Obstet Gynecol 117:1065-70. 2011..To estimate whether weight loss or low gestational weight gain in class I-III obese women is associated with adverse maternal and neonatal outcomes compared with gestational weight gain within the new Institute of Medicine recommendations...
- Secular trends of macrosomia in southeast China, 1994-2005Yanyu Lu
School of Public Health, Peking University Health Science Center, Beijing 100191, China
BMC Public Health 11:818. 2011....
- Management of suspected fetal macrosomiaM A Zamorski
Department of Family Medicine, University of Michigan Medical School, Ann Arbor 49109, USA
Am Fam Physician 63:302-6. 2001b>Fetal macrosomia, arbitrarily defined as a birth weight of more than 4,000 g (8 lb, 13 oz) complicates more than 10 percent of all pregnancies in the United States...
- [The delivery of macrosomic infants weighing 4500 g and more. A report of 61 cases]Jamel Kraiem
Clinique universitaire de gynécologie obstétrique, Hôpital Mohamed Telatli, Nabeul, Tunisie
Tunis Med 82:656-61. 2004..With literature review, we confirm the increased risk of shoulder dystocia, birth asphyxia and hypoglycemia for these infants. So, we believe that cesarean delivery is justified in all cases of fetal weight estimation > 4500g...
- Maternal weight characteristics influence recurrence of fetal macrosomia in women with normal glucose toleranceRhona Mahony
UCD Obstetrics and Gynaecology, University College of Dublin, National Maternity Hospital, Dublin, Ireland
Aust N Z J Obstet Gynaecol 47:399-401. 2007..Recurrence of fetal macrosomia was associated with greater maternal body mass index (P = 0.032), greater initial pregnancy weight (P < 0...
- Pre-pregnant body mass index, weight gain and the risk of delivering large babies among non-diabetic mothersC Kabali
Boston University School of Public Health, Boston, Massachusetts, USA
Int J Gynaecol Obstet 97:100-4. 2007..However, previous studies have focused on the separate effects of these two indices of weight in diabetic women...
- Echocardiographic measurements in infants of diabetic mothers and macrosomic infants of nondiabetic mothersKaan Demiroren
Department of Pediatrics, Meram Medicine Faculty, Selcuk University, Konya, Turkey
J Perinat Med 33:232-5. 2005..To compare echocardiographic findings of infants of diabetic mothers (IDMs), macrosomic infants of nondiabetic mothers and healthy full term appropriate-for-gestational-age (AGA) infants...
- Reasons for increasing trends in large for gestational age birthsPamela J Surkan
Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden
Obstet Gynecol 104:720-6. 2004....
- Value of a single early third trimester fetal biometry for the prediction of birth weight deviations in a low risk populationPaul A O M De Reu
Midden Brabant Midwifery Care Center, Boxtel, The Netherlands
J Perinat Med 36:324-9. 2008..The aim of this study was to develop a simple and useful method for the detection of growth deviations during pregnancy in primary care (midwife or general practitioner) practices...
- N-3 fatty acids modulate antioxidant status in diabetic rats and their macrosomic offspringA Yessoufou
Department of Physiology, UPRES Lipids and Nutrition, Faculty of Life Sciences, University of Burgundy, Dijon, France
Int J Obes (Lond) 30:739-50. 2006..We investigated the role of dietary n-3 polyunsaturated fatty acids (n-3 PUFA) in the modulation of total antioxidant status in streptozotocin (STZ)-induced diabetic rats and their macrosomic offspring...
- Antioxidant status and circulating lipids are altered in human gestational diabetes and macrosomiaOussama Grissa
Department of Physiology and Functional Explorations, Farhat Hached University Hospital, 4000 Sousse, Tunisia
Transl Res 150:164-71. 2007..These results suggest that human GDM and macrosomia are associated with downregulation of antioxidant status, and macrosomic infants also exhibit altered lipid metabolism...
- Modulation of lipid metabolism by n-3 polyunsaturated fatty acids in gestational diabetic rats and their macrosomic offspringNassima A Soulimane-Mokhtari
Departement de Biologie, Faculte des Sciences, université de Tlemcen, Algerie
Clin Sci (Lond) 109:287-95. 2005..Since the EPAX diet improves lipid anomalies considerably in diabetic mothers and their macrosomic offspring, it may prevent long-term metabolic abnormalities associated with macrosomia...
- Suspicion and treatment of the macrosomic fetus: a reviewSuneet P Chauhan
Spartanburg Regional Medical Center, Spartanburg, SC, USA
Am J Obstet Gynecol 193:332-46. 2005..To review the prevalence of and our ability to identify macrosomic (birthweight >4000 g) fetuses. Additionally, based on the current evidence, propose an algorithm for treatment of suspected macrosomia...
- Maternal obesity and pregnancy: a retrospective studyAngela M Kerrigan
Midwifery Research Department, Room 54, Antenatal Clinic, Liverpool Women s NHS Foundation Trust, Crown Street, Liverpool L8 7SS, UK
Midwifery 26:138-46. 2010..to establish the incidence of obesity in the pregnant population in a large city in the North West of England, identify links between obesity and social deprivation, and compare outcomes of pregnancy in obese and non-obese women...
- Maternal obesity: consequences for children, challenges for clinicians and carersW McGuire
Hull York Medical School, University of York, York, UK
Semin Fetal Neonatal Med 15:108-12. 2010..evidence for the association of maternal obesity with congenital structural neural tube and cardiac defects, fetal macrosomia that predisposes infants to birth injuries and to problems with physiological and metabolic transition, as ..
- No loss of genomic imprinting of IGF-II and H19 in placentas of diabetic pregnancies with fetal macrosomiaA Vambergue
Department of Endocrinology and Diabetes, Marc Linquette Hospital, CHRU Lille, France
Growth Horm IGF Res 17:130-6. 2007b>Fetal macrosomia is a common complication of maternal diabetes mellitus and is associated with substantial morbidity, but the precise cellular and molecular mechanisms that induce fetal macrosomia are not well understood...
- Trends in birth size and macrosomia in Queensland, Australia, from 1988 to 2005Petra H Lahmann
The University of Queensland, School of Population Health, Herston Qld, Australia
Paediatr Perinat Epidemiol 23:533-41. 2009..The trend in rising BW remained after controlling for other perinatal characteristics. Birth measures per se and related trends differed by Indigenous status and warrant further investigation...
- Macrosomia: mode of delivery and pregnancy outcomeAstrid R Bjørstad
Locus for Registry Based Epidemiology, Department of Public Health and Primary Health Care, University of Bergen, Kalfarveien 31, Bergen, Norway
Acta Obstet Gynecol Scand 89:664-9. 2010..To assess associations between birthweight and selected adverse outcomes in vaginal and cesarean deliveries and to clarify to which extent macrosomic births are delivered by cesarean section or are centralized to larger maternity units...
- Secular trends in neonatal macrosomia in Berlin: influences of potential determinantsRenate L Bergmann
Department of Obstetrics, Charité Virchow Hospitals of the Humboldt University, Berlin, and Robert Koch Institute, Berlin, Germany
Paediatr Perinat Epidemiol 17:244-9. 2003..37.[3.22, 3.53]) and for recognised diabetes (1.85.[1.69, 2.04]). It is speculated that this increase in the prevalence of neonatal macrosomia may contribute to the secular trend of overweight and obesity under affluent living conditions...
- Inverse changes in fetal insulin-like growth factor (IGF)-1 and IGF binding protein-1 in association with higher birth weight in maternal diabetesRobert S Lindsay
BHF Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, Scotland, UK
Clin Endocrinol (Oxf) 66:322-8. 2007..We examined IGF-1 and IGF binding protein-1 (IGFBP-1) concentrations in cord blood samples from offspring of mothers with gestational and type 2 diabetes...
- Macrosomic births in the united states: determinants, outcomes, and proposed grades of riskSheree L Boulet
Department of Maternal and Child Health, School of Public Health, University of Alabama at Birmingham, 3230 A Ryals Building, 1665 University Boulevard, Birmingham, AL 35294 0022, USA
Am J Obstet Gynecol 188:1372-8. 2003..We describe maternal risk factors for macrosomia and assess birth weight categories to determine predictive thresholds of adverse outcomes...
- Gestational weight gain, macrosomia, and risk of cesarean birth in nondiabetic nulliparasNaomi E Stotland
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California San Francisco, 1001 Potrero Avenue, San Francisco, CA 94110, USA
Obstet Gynecol 104:671-7. 2004..To examine how the association between excessive weight gain and cesarean birth is modified by infant birth weight in nondiabetic women...
- Is fetal macrosomia related to blood pressure among adolescents? A birth cohort study in ChinaY Li
1 School of Public Health, Public Health Security Key Laboratory of the Ministry of Education, Fudan University, Shanghai, China 2 Department of Epidemiology and Social Science on Reproductive Health, National Population and Family Planning Key Laboratory of Contraceptive Drugs and Devices, Shanghai Institute of Planned Parenthood Research, Shanghai, China
J Hum Hypertens 27:686-92. 2013..Multi-mixed models in SAS were used to control for repeated measures to explore the effects of fetal macrosomia on BP. At the inception of the cohort, 1595 pairs of participants were recruited...
- The influence of macrosomia on the duration of labor, the mode of delivery and intrapartum complicationsW Siggelkow
Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany
Arch Gynecol Obstet 278:547-53. 2008..This study assessed the perinatal outcome in a series of macrosomic fetuses with mothers from a general obstetric population in whom vaginal delivery was planned...
- Fetal macrosomia and adolescence obesity: results from a longitudinal cohort studyY Wang
Shanghai Institute for Planned Parental Research, Shanghai, China
Int J Obes (Lond) 33:923-8. 2009To assess the association between fetal macrosomia and adolescent obesity.
- Perinatal outcome of fetuses with a birth weight greater than 4500 g: an analysis of 3356 casesLuigi Raio
Department of Obstetrics and Gynecology, University of Berne Inselspital, Effingerstrasse 102, 3010 Berne, Switzerland
Eur J Obstet Gynecol Reprod Biol 109:160-5. 2003....
- Fundal height: a useful screening tool for fetal growth?Teresa N Sparks
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, California, USA
J Matern Fetal Neonatal Med 24:708-12. 2011..To determine the utility of fundal height in screening for small-for-gestational-age (SGA) and large-for-gestational-age (LGA) neonates at term...
- Is prenatal identification of fetal macrosomia useful?Françoise Vendittelli
AUDIPOG Sentinel Network Association des Utilisateurs de Dossiers Informatisés en Pédiatrie, Obstétrique et Gynécologie, Faculté de médecine Lyon Est, Lyon, France
Eur J Obstet Gynecol Reprod Biol 161:170-6. 2012..To determine whether prenatal identification of macrosomia (≥4000g) reduces neonatal complications and maternal perineal lesions during delivery...
- Maternal and neonatal outcomes of large for gestational age pregnanciesAlina Weissmann-Brenner
Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Tel Hashomer, Israel
Acta Obstet Gynecol Scand 91:844-9. 2012..To compare maternal and neonatal outcomes of term large for gestational age (LGA) pregnancies and adequate for gestational age (AGA) pregnancies...
- Fetal macrosomia and shoulder dystocia in women with gestational diabetes: risks amenable to treatment?Brett C Young
Massachusetts General Hospital, Division of Maternal Fetal Medicine, 55 Fruit Street, Founders 4th Floor, Boston, MA 02114, USA
Curr Diab Rep 13:12-8. 2013b>Fetal macrosomia and maternal diabetes are independent risk factors for shoulder dystocia, an obstetrical emergency that may cause permanent neonatal injury...
- Maternal and infant complications in high and normal weight infants by method of deliveryK D Gregory
Department of Obstetrics and Gynecology, Cedars Sinai Medical Center, University of California at Los Angeles, School of Medicine, 90048, USA
Obstet Gynecol 92:507-13. 1998..To estimate the population risks of maternal and infant complications with the birth of macrosomic (at least 4000 g) compared with normal weight infants...
- Prediction of fetal macrosomia with ultrasound parameters and maternal glycemic controls in gestational diabetes mellitusM Gojnic
Clinical Centre of Serbia, Institute of Gynecology and Obstetrics, Faculty of Medicine Belgrade, University of Belgrade, Serbia
Clin Exp Obstet Gynecol 39:512-5. 2012..of ultrasound measurements of fetal adipose subcutaneous tissue (ASCT), abdominal circumference (AC), liver length (LL), and amniotic fluid index (AFI) in prediction of fetal macrosomia (FM) and gestational diabetes mellitus (GDM).
- Low gestational weight gain improves infant and maternal pregnancy outcomes in overweight and obese Korean women with gestational diabetes mellitusJeong Eun Park
Division of Endocrinology and Metabolism, Department of Medicine, Cheil General Hospital and Women s Healthcare Center, Seoul, Korea
Gynecol Endocrinol 27:775-81. 2011....
- Increased composite maternal and neonatal morbidity associated with ultrasonographically suspected fetal macrosomiaJennifer R King
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
J Matern Fetal Neonatal Med 25:1953-9. 2012To determine the composite risk of maternal and neonatal morbidity in pregnancies with suspected fetal macrosomia.
- Is fetal macrosomia in adequately controlled diabetic women the result of a placental defect?--a hypothesisG Desoye
Clinic of Obstetrics and Gynecology, Karl Franzens University, Graz, Austria
J Matern Fetal Neonatal Med 11:258-61. 2002b>Fetal macrosomia may occur even in adequately controlled diabetic mothers...
- Sonographic prediction of fetal macrosomia: the consequences of false diagnosisNir Melamed
Helen Schneider Hospital for Women, Rabin Medical Center, Beilinson Campus, 49100 Petach Tikva, Israel
J Ultrasound Med 29:225-30. 2010..The purpose of this study was to determine the effect of false diagnosis of macrosomia (<4500 g) on maternal/perinatal outcomes...
- Prediction and prevention of the macrosomic fetusJennifer M Walsh
UCD Obstetrics and Gynaecology, School of Medicine and Medical Science, University College Dublin, National Maternity Hospital, Dublin, Ireland
Eur J Obstet Gynecol Reprod Biol 162:125-30. 2012b>Fetal macrosomia is associated with significant maternal and neonatal morbidity...
- Mode of delivery and birth outcomes of macrosomic infantsS L Boulet
Department of Maternal and Child Health, School of Public Health, University of Alabama at Birmingham, Birmingham, Alabama 35294 0022, USA
J Obstet Gynaecol 24:622-9. 2004..Consequently, an optimal management strategy has yet to be defined...
- Fetal anterior abdominal wall thickness in diabetic pregnancyMary F Higgins
National Maternity Hospital, University College Dublin, Dublin, Ireland
Eur J Obstet Gynecol Reprod Biol 140:43-7. 2008..The purpose of this study was to investigate whether third trimester fetal anterior abdominal wall (AAW) thickness in diabetic pregnancy reflects glycaemic control and predicts macrosomia...
- Fetal macrosomia in African women: a study of 249 casesC I Kamanu
Department of Obstetrics and Gynaecology, Abia State University Teaching Hospital, PMB, Aba, Nigeria
Arch Gynecol Obstet 279:857-61. 2009..To determine the incidence and risk factors of macrosomia in a Nigerian centre, and to assess the relation of maternal body mass index (BMI) at birth and of the total weight gain during pregnancy to macrosomia and adverse pregnancy outcome...
- Maternal characteristics and lifestyle factors and the risk of delivering high birth weight infantsJanne Ørskou
Perinatal Epidemiological Research Unit, Department of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark
Obstet Gynecol 102:115-20. 2003....
- Delivery of macrosomic babies: management and outcomes of 330 casesJiun How Lim
Department of Obstetrics and Gynaecology, University Putra Malaysia, Kuala Lumpur, Malaysia
J Obstet Gynaecol 22:370-4. 2002..However, shoulder dystocia remains a significant complication of vaginal delivery for macrosomic fetuses...
- Interventions for pregnant women with hyperglycaemia not meeting gestational diabetes and type 2 diabetes diagnostic criteriaShanshan Han
ARCH Australian Research Centre for Health of Women and Babies, Discipline of Obstetrics and Gynaecology, The University ofAdelaide, Adelaide, Australia
Cochrane Database Syst Rev 1:CD009037. 2012....
- Fetal macrosomia at the University College Hospital, Ibadan: a 3-year reviewO A Adesina
Department of Obstetrics and Gynaecology, University College Hospital, Ibadan, Nigeria
J Obstet Gynaecol 23:30-3. 2003..to determine the maternal characteristics and contribution to obstetric morbidity of infants presenting with fetal macrosomia at the University College Hospital, Ibadan. This was a retrospective study...
- Intrapartum prediction of macrosomia: accuracy of abdominal circumference estimationH Al-Inany
Department of Obstetrics and Gynecology, Cairo University, Cairo, Egypt
Gynecol Obstet Invest 51:116-9. 2001..To evaluate the accuracy of abdominal circumference (AC) estimation of macrosomia early in labor and whether a cutoff value could be detected...
- The association of maternal and fetal glucose homeostasis with fetal adiposity and birthweightJennifer M Walsh
Department of Obstetrics and Gynecology, School of Medicine and Medical Science, University College Dublin, Dublin, Ireland
Eur J Obstet Gynecol Reprod Biol 159:338-41. 2011..To examine the association between maternal and fetal glucose levels and fetal adiposity and infant birthweight...
- Fetal macrosomia in non-diabetic mothers: antenatal diagnosis and delivery outcomeC Bailey
Chelsea and Westminster Hospital, London, UK
J Obstet Gynaecol 29:206-8. 2009..Those women in whom macrosomia was not suspected had higher rates of vaginal deliveries without any increase in neonatal morbidity...
- The peri-partum management of pregnancies with macrosomic babies weighing > or =4,500 g at a tertiary University HospitalO B Navti
Department of Cancer and Molecular Medicine, Leicester Royal Infirmary, Leicester, UK
J Obstet Gynaecol 27:267-70. 2007The management of fetal macrosomia diagnosed antenatally presents a dilemma to the obstetrician...
- Recurrence of fetal macrosomia in non-diabetic pregnanciesC A Walsh
National Maternity Hospital Dublin, Ireland
J Obstet Gynaecol 27:374-8. 2007b>Fetal macrosomia (birth weight >/=4,500 g) is known to increase a number of adverse maternal and perinatal outcomes...
- A study of fetal macrosomiaK Wollschlaeger
Universitatsfrauenklinik, Magdeburg, Germany
Arch Gynecol Obstet 263:51-5. 1999We describe the maternal characteristics in pregnancy with fetal macrosomia, fetal and maternal complications related to macrosomia, and the risk of impaired glucose tolerance...
- Ponderal index and disproportionate fetal growth in IDDM pregnanciesJ Djelmis
Department of Obstetrics and Gynaecology, School of Medicine, University of Zagreb, Croatia
Coll Antropol 22:491-5. 1998..The rate of disproportionate macrosomic infants significantly differ among study group...
- Ultrasonographic prediction of fetal macrosomia. Association with cesarean deliveryS Parry
Department of Obstetrics and Gynecology, University of Pennsylvania Medical Center, Philadelphia 19104 4283, USA
J Reprod Med 45:17-22. 2000..To investigate whether the incorrect ultrasonographic prediction of macrosomia affects the cesarean delivery rate among nonmacrosomic neonates...
- Fetal macrosomia greater than or equal to 4000 grams. Comparing maternal and neonatal outcomes in diabetic and nondiabetic womenAhmed Saleh
Department of Obstetrics and Gynecology, Riyadh Military Hospital, Riyadh, Kingdom of Saudi Arabia
Saudi Med J 29:1463-9. 2008To compare maternal and neonatal outcomes of fetal macrosomia in diabetic and nondiabetic women.
- Glucose tolerance of 2- to 5-yr-old offspring of diabetic mothersJurate Buinauskiene
Department of Neonatology, Kaunas University of Medicine, Kaunas, Lithuania
Pediatr Diabetes 5:143-6. 2004..Macrosomia after birth, overweight, and obesity in childhood had a significant influence on the glucose tolerance of the ODM. The results of the oral glucose tolerance test correlated with the length of breastfeeding...
- Increased farnesylation of p21-Ras and neonatal macrosomia in women with gestational diabetesPatti Thureen
Department of Pediatrics, Medicine of the University of Colorado Health Sciences Center, Research Service of the Denver Veterans Affairs Medical Center, Colorado, USA
J Pediatr 149:871-3. 2006..The ability of fetal hyperinsulinemia to increase the availability of farnesylated p21-Ras may represent one mechanism of the growth-promoting action of insulin during fetal development...
- Fetal macrosomia: obstetric outcome of 311 cases in UNTH, Enugu, NigeriaH U Ezegwui
Department of Obstetrics and Gynaecology, Anambra State University Teaching Hospital, Amaku, Awka, Nigeria
Niger J Clin Pract 14:322-6. 2011In modern obstetrics, fetal macrosomia is a major contributor to obstetric morbidity. It is an important cause of perinatal morbidity and mortality.
- Estimating fetal weight in the management of macrosomiaD A Sacks
Department of Obstetrics and Gynecology, Kaiser Foundation Hospital, Bellflower, California 90706, USA
Obstet Gynecol Surv 55:229-39. 2000The purpose of this review is to examine the evidence that, including estimates of fetal macrosomia in patient care, will decrease adverse perinatal outcomes. A literature search for the years 1980 to 1999 was used...
- Detecting fetal macrosomia with abdominal circumference aloneChristine Henrichs
Division of Maternal Fetal Medicine, Spartanburg Regional Medical Center, Spartanburg, South Carolina, USA
J Reprod Med 48:339-42. 2003..To determine if abdominal circumference (AC) can identify macrosomia (> or = 4,000 g) at or beyond 37 weeks...
- Accuracy of ultrasound biometry in the prediction of macrosomia: a systematic quantitative reviewArri Coomarasamy
Education Resource Centre, Birmingham Women s Hospital, UK
BJOG 112:1461-6. 2005..To determine the accuracy of ultrasonographically estimated fetal weight (EFW) and abdominal circumference (AC) in the prediction of macrosomia...
- Sonographic estimate of birth weight: relative accuracy of sonographers versus maternal-fetal medicine specialistsJ Humphries
Maternal Fetal Medicine Department, Spartanburg Regional Center, South Carolina, USA
J Matern Fetal Neonatal Med 11:108-12. 2002..To compare the relative accuracy of predicting birth weight among registered diagnostic medical sonographers versus maternal-fetal medicine specialists...
- Perinatal consequences of fetal macrosomia: Zhang et alChristina M Scifres
Division of Maternal Fetal Medicine, Washington University in St Louis, School of Medicine, St Louis, MO, USA
Am J Obstet Gynecol 198:603-4; discussion e1-5. 2008
- Macrosomia and hyperinsulinaemic hypoglycaemia in patients with heterozygous mutations in the HNF4A geneEwan R Pearson
Peninsula Medical School, Exeter, United Kingdom
PLoS Med 4:e118. 2007....
- Animal evidence for the transgenerational development of diabetes mellitusL Aerts
Department of Developmental Biology, UZ Gasthuisberg, KULeuven, Belgium
Int J Biochem Cell Biol 38:894-903. 2006..The concept of fetal origin of adult diabetes therefore is of major significance for public health in the immediate and the far future...
- The association between birthweight 4000 g or greater and perinatal outcomes in patients with and without gestational diabetes mellitusTania F Esakoff
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, School of Medicine, San Francisco, CA, USA
Am J Obstet Gynecol 200:672.e1-4. 2009..The objective of the study was to examine the association between birthweight of 4000 g or greater and perinatal outcomes in women with and without gestational diabetes mellitus (GDM)...
- Pregnancy outcome and prepregnancy body mass index in 2459 glucose-tolerant Danish womenDorte M Jensen
Department of Endocrinology, Odense University Hospital, Odense, Denmark
Am J Obstet Gynecol 189:239-44. 2003..This study was undertaken to investigate the relationship between pregnancy outcome and prepregnancy overweight or obesity in women with a normal glucose tolerance test...
- Determinants of fetal growth at different periods of pregnancies complicated by gestational diabetes mellitus or impaired glucose toleranceUte M Schaefer-Graf
Department of Obstetrics, Charite, Campus Virchow Klinikum, Humboldt University, Berlin, Germany
Diabetes Care 26:193-8. 2003..To determine maternal parameters with the strongest influence on fetal growth in different periods of pregnancies complicated by an abnormal glucose tolerance test (GTT)...
- Age-related changes in cholesterol metabolism in macrosomic offspring of rats with streptozotocin-induced diabetesH Merzouk
Laboratoire de Physiologie Animale, , , , Algeria
J Lipid Res 42:1152-9. 2001..However, cholesterol oversynthesis exceeded its removal and was a major contributor to hypercholesterolemia in adult macrosomic rats. In conclusion, macrosomia was associated with alterations in cholesterol metabolism through adulthood...
- Macrosomic newborns: a 3-year reviewYasemin Akin
Department of Pediatrics I, Dr Lutfi Kirdar Kartal Training and Research Hospital, Istanbul, Turkey
Turk J Pediatr 52:378-83. 2010..the high birth trauma and NICU admission rates of macrosomic infants, it is important to emphasize the significance of prenatal diagnosis of fetal macrosomia and of management of these high-risk pregnancies in tertiary level hospitals.
- Postpartum oral glucose tolerance tests in mothers of macarosomic infants: inadequacy of current antenatal test criteria in detecting prediabetic stateO Bukulmez
Department of Obstetrics and Gynecology, Hacettepe University School of Medicine, Ankara, Turkey
Eur J Obstet Gynecol Reprod Biol 86:29-34. 1999..To assess the presence of subtle carbohydrate metabolism abnormalities in otherwise healthy mothers who have given macrosomic birth by utilizing postpartum oral glucose tolerance test (PPOGTT)...
- Expectant management versus labor induction for suspected fetal macrosomia: a systematic reviewLuis Sanchez-Ramos
Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, University of Florida, Jacksonville, Florida 32209, USA
Obstet Gynecol 100:997-1002. 2002To systematically review and summarize the medical literature regarding the effects of expectant management and labor induction on mode of delivery and perinatal outcomes in patients with suspected fetal macrosomia.
- Fetal macrosomia--a continuing obstetric challengeNonna Heiskanen
Department of Obstetrics and Gynecology, Kuopio University Hospital, Kuopio, Finland
Biol Neonate 90:98-103. 2006..Macrosomic fetuses represent a continuing challenge in obstetrics...
- Fetal macrosomia and maternal weight gain during pregnancyJ Lepercq
Service de Gynecologie Obstetrique, Hopital Cochin, Saint Vincent de Paul, AP HP, Universite Paris V, France
Diabetes Metab 28:323-8. 2002To calculate an adjusted maternal weight gain during pregnancy including infant and placental weights to the actual weight gain and secondarily examine its influence on the occurrence of fetal macrosomia.
- Relationship of adiponectin and resistin levels in umbilical and maternal serum with fetal macrosomiaJing Wang
Department of Obstetrics and Gynecology, General Hospital of Beijing Military Command, Beijing, China
J Obstet Gynaecol Res 36:533-7. 2010..However, correlations between adiponectin and resistin levels in umbilical and maternal serum and fetal macrosomia remain poorly understood...
- Antepartum detection of macrosomic fetus: clinical versus sonographic, including soft-tissue measurementsS P Chauhan
Spartanburg Regional Medical Center, Spartanburg, South Carolina, USA
Obstet Gynecol 95:639-42. 2000..To compare clinical and sonographic estimates of birth weights with five new estimation techniques that involve measurements of soft tissue, for identifying newborns with birth weights of at least 4000 g...
- Body mass index has a greater impact on pregnancy outcomes than gestational hyperglycaemiaW Ricart
Unit of Diabetes, Endocrinology and Nutrition, University Hospital Doctor Josep Trueta, Avgda de França s n, 17007, Girona, Spain
Diabetologia 48:1736-42. 2005..We evaluated diabetes-related pregnancy outcomes in a cohort of Spanish women in relation to their glucose tolerance status, prepregnancy BMI and other predictive variables...
- The Common Marmoset as a Primate Model of Maternal ObesitySUZETTE D contact TARDIF; Fiscal Year: 2010..females, regardless of the source of obesity will display a "pre-diabetic/mild diabetic" profile resulting in fetal macrosomia and hyperinsulinemia, that the DIO propensity group may differ from the diet resistant, lean group in terms ..
- DIET GLYCEMIC LOAD & METABOLISM IN OBESE PREGNANT WOMENJanet King; Fiscal Year: 2009..3) to determine if consuming low GL diets the last half of pregnancy reduces the prevalence of GDM and fetal macrosomia. At 28 and 34 weeks, the hormonal and substrate response will be measured to a standard 100 g oral glucose ..
- PATHOGENESIS OF FETAL MACROSOMIA IN MATERNAL DIABETESYEE KIM; Fiscal Year: 1980..4. Litter mates from the same mothers will be used to examine the parameters mentioned above in order to elucidate the relationship between maternal metabolism and fetal metabolism...
- OMEGA-3 SUPPLMENTATION DECREASES INFLAMMATION AND FETAL OBESITY IN PREGNANCYSylvie Hauguel De Mouzon; Fiscal Year: 2010..Pretiminary data witt also be obtained on fetat body composition in order to later address the prevention of the long term adverse effects (devetopmental programming) of maternal obesity in the developing fetus. ..
- CENTER FOR STUDY OF GROWTH REGULATION IN HUMAN PREGNANCYPatrick Catalano; Fiscal Year: 2004..abstract_text> ..
- GESTATIONAL DIABETES: DIAGNOSTIC CRITERIA AND OUTCOMESAssiamira Ferrara; Fiscal Year: 2003....
- Comparative effectiveness of diabetes prevention strategies in women with GDMAssiamira Ferrara; Fiscal Year: 2010..Finding that this intervention is cost-effective in this setting should motivate its adoption at KP as well as in other health care systems. ..
- Improving primary care to prevent childhood obesityMatthew Gillman; Fiscal Year: 2009....
- Popular Diets, Metabolism, and CVD RiskDavid Ludwig; Fiscal Year: 2008..This study should have major public health implications to the millions of Americans currently following diets to decrease body weight and risk for CVD. ..
- GENERAL CLINICAL RESEARCH CENTERE Reece; Fiscal Year: 2009..During the upcoming grant period, we anticipate the planning and funding of the UM Clinical and Translational Science Center. ..
- Maternal overnutrition and offspring fat mass, metabolic and vascular function.Debbie Lawlor; Fiscal Year: 2009....
- Reducing Sugar-Sweetened Beverage Consumption in Overweight AdolescentsDavid S Ludwig; Fiscal Year: 2010..These results should have immediat public health application, and aid in the design of future, comprehensive obesity prevention interventions. ..
- Maternal vitamin D, adiposity in early life, and risk of childhood asthma.Matthew W Gillman; Fiscal Year: 2010..This work also brings together a multidisciplinary research team with a proven track record of collaboration and expertise in nutritional, respiratory, and pediatric epidemiology. ..
- Risk factors for medically indicated preterm birth in a Latin American populationCLAUDIO GERARDO SOSA; Fiscal Year: 2010..The long-term goal of this research program is to develop intervention strategies that are based on the risk factors identified in the proposed study resulting in decreased morbidity and mortality. ..
- Hyperglycemia and adverse pregnancy outcome (HAPO)Boyd E Metzger; Fiscal Year: 2010..This application requests 4 years of additional funding for the CCC, to allow HAPO to achieve its recruitment goal of 25,000 women, complete all data collection on all enrolled women, and complete all data analyses. ..
- Mentored Patient-Oriented Research Career Development AwardLinda Barbour; Fiscal Year: 2006..abstract_text> ..
- Increasing Blood and Cord Blood Donation in BlacksMichael DeBaun; Fiscal Year: 2006....
- Human Subjects Research Electronic Tracking SystemDonald Wilson; Fiscal Year: 2003..WVU has a different organizational structure, a different information technology network, and different human subjects research emphasis from the University of Maryland School of Medicine. ..
- Hormone markers during pregnancy and ovarian concer riskSven Cnattingius; Fiscal Year: 2005..The Swedish research registers will allow us to perform a large cost-effective cohort study where information on markers of hormone exposure during pregnancy has been collected prospectively. ..
- OXIDATIVE STRESS, ANTIOXIDANT STATUS & PREGNANCY OUTCOMETheresa Scholl; Fiscal Year: 2005....
- Glycemic Index, Obesity, Insulin Resistance and CVD RiskDavid Ludwig; Fiscal Year: 2005..The project's key personnel and consultants include individuals with a diversity of expertise and perspective, ensuring a rigorous and impartial evaluation of study hypotheses. ..
- Sugar-sweetened Beverages and Weight Gain in ChildrenDavid Ludwig; Fiscal Year: 2003..abstract_text> ..
- UTERINE VASCULAR RESPONSE TO STEROID SIGNALINGIra Bernstein; Fiscal Year: 2002..abstract_text> ..
- International Congress--Origins of Health and DiseaseMatthew Gillman; Fiscal Year: 2005..For trainees and young investigators, the program will include a welcome reception/awards ceremony, meet-the-professor luncheon roundtables, reduced registration fees, and travel stipends. ..
- CONSTRUCTION OF RESEARCH ANIMAL FACILITYDonald Wilson; Fiscal Year: 2002..The proposed project, which will be co-financed by contributions from the State of Maryland, therefore, considered instrumental for sustaining the stature of the MPRC in schizophrenia research. ..
- EXTRAMURAL RESEARCH FACILITIES IMPROVEMENT PROVEMENTDonald Wilson; Fiscal Year: 2003....
- Pre- and peri-natal predictors of childhood obesityMatthew Gillman; Fiscal Year: 2009..The results of this study promise to unravel some knotty epidemiologic issues in the early origins of obesity, and to open up new potential avenues for primordial obesity prevention. ..
- Maternal fatty acids, child obesity, and asthma immunityMatthew Gillman; Fiscal Year: 2007..This work also brings together a multidisciplinary research team with a proven track record of collaboration and expertise in immunology, epidemiology, and biostatistics. ..
- Glycemic Load and infant birth weight in pregnant/glucose intolerant womenDavid Ludwig; Fiscal Year: 2007..A successful outcome of this study will provide preliminary data upon which to design a multi- centered clinical trial. [unreadable] [unreadable] [unreadable]..
- GENERAL CLINICAL RESEARCH CENTERAUBREY MD HOUGH; Fiscal Year: 2006..In this second funding cycle, the UAMS GCRC will continue expanding campus-wide clinical investigation. Support from all three sister institutions will continue to ensure GCRC success. ..
- Regulation of Maternal Fuel Supply and Neonatal AdiposityLinda Barbour; Fiscal Year: 2008..Such information may result in new treatment strategies in pregnant women to normalize fetal growth. ..
- Cancer Center Renovation GrantDonald Wilson; Fiscal Year: 2004....