continuous positive airway pressure

Summary

Summary: A technique of respiratory therapy, in either spontaneously breathing or mechanically ventilated patients, in which airway pressure is maintained above atmospheric pressure throughout the respiratory cycle by pressurization of the ventilatory circuit. (On-Line Medical Dictionary [Internet]. Newcastle upon Tyne(UK): The University Dept. of Medical Oncology: The CancerWEB Project; c1997-2003 [cited 2003 Apr 17]. Available from: http://cancerweb.ncl.ac.uk/omd/)

Top Publications

  1. ncbi Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial
    Ferran Barbe
    Coordinator Centre, IRB Lleida, Lleida, Spain
    JAMA 307:2161-8. 2012
  2. ncbi Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study
    Jose M Marin
    Respiratory Service, Hospital Universitario Miguel Servet, Isabel la Catolica, Zaragoza, Spain
    Lancet 365:1046-53. 2005
  3. ncbi Obstructive sleep apnoea and its cardiovascular consequences
    T Douglas Bradley
    Sleep Research Laboratory of the Toronto Rehabilitation Institute, Toronto, Canada
    Lancet 373:82-93. 2009
  4. pmc Early CPAP versus surfactant in extremely preterm infants
    Neil N Finer
    N Engl J Med 362:1970-9. 2010
  5. ncbi CPAP for the metabolic syndrome in patients with obstructive sleep apnea
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    N Engl J Med 365:2277-86. 2011
  6. pmc Adherence to continuous positive airway pressure therapy: the challenge to effective treatment
    Terri E Weaver
    Division of Biobehavioral and Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, PA 19104 6096, USA
    Proc Am Thorac Soc 5:173-8. 2008
  7. ncbi The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syndrome: evidence from a meta-analysis of placebo-controlled randomized trials
    Patrick Haentjens
    Center for Outcomes Research and Laboratory for Experimental Surgery, Endocrinology, Pharmacology, and General Internal Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium
    Arch Intern Med 167:757-64. 2007
  8. ncbi Nasal CPAP or intubation at birth for very preterm infants
    Colin J Morley
    Neonatal Services, Royal Women s Hospital, Melbourne, Australia
    N Engl J Med 358:700-8. 2008
  9. ncbi Obstructive sleep apnea: brain structural changes and neurocognitive function before and after treatment
    Nicola Canessa
    Center for Cognitive Neuroscience, Vita Salute San Raffaele University, Milan, Italy
    Am J Respir Crit Care Med 183:1419-26. 2011
  10. ncbi Cardiovascular mortality in women with obstructive sleep apnea with or without continuous positive airway pressure treatment: a cohort study
    Francisco Campos-Rodriguez
    Valme University Hospital, Seville, Spain
    Ann Intern Med 156:115-22. 2012

Detail Information

Publications368 found, 100 shown here

  1. ncbi Effect of continuous positive airway pressure on the incidence of hypertension and cardiovascular events in nonsleepy patients with obstructive sleep apnea: a randomized controlled trial
    Ferran Barbe
    Coordinator Centre, IRB Lleida, Lleida, Spain
    JAMA 307:2161-8. 2012
    b>Continuous positive airway pressure (CPAP) is the first-line treatment for patients with symptomatic obstructive sleep apnea (OSA)...
  2. ncbi Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study
    Jose M Marin
    Respiratory Service, Hospital Universitario Miguel Servet, Isabel la Catolica, Zaragoza, Spain
    Lancet 365:1046-53. 2005
    ..as a cardiovascular risk factor and the potential protective effect of its treatment with continuous positive airway pressure (CPAP) is unclear...
  3. ncbi Obstructive sleep apnoea and its cardiovascular consequences
    T Douglas Bradley
    Sleep Research Laboratory of the Toronto Rehabilitation Institute, Toronto, Canada
    Lancet 373:82-93. 2009
    ..In randomised trials, treating OSA with continuous positive airway pressure lowered blood pressure, attenuated signs of early atherosclerosis, and, in patients with heart ..
  4. pmc Early CPAP versus surfactant in extremely preterm infants
    Neil N Finer
    N Engl J Med 362:1970-9. 2010
    There are limited data to inform the choice between early treatment with continuous positive airway pressure (CPAP) and early surfactant treatment as the initial support for extremely-low-birth-weight infants.
  5. ncbi CPAP for the metabolic syndrome in patients with obstructive sleep apnea
    Surendra K Sharma
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    N Engl J Med 365:2277-86. 2011
    ..It is unclear whether treatment of obstructive sleep apnea syndrome with continuous positive airway pressure (CPAP) would modify these outcomes.
  6. pmc Adherence to continuous positive airway pressure therapy: the challenge to effective treatment
    Terri E Weaver
    Division of Biobehavioral and Health Sciences, School of Nursing, University of Pennsylvania, Philadelphia, PA 19104 6096, USA
    Proc Am Thorac Soc 5:173-8. 2008
    Despite the high efficacy of continuous positive airway pressure (CPAP) to reverse upper airway obstruction in sleep apnea, treatment effectiveness is limited by variable adherence to prescribed therapy...
  7. ncbi The impact of continuous positive airway pressure on blood pressure in patients with obstructive sleep apnea syndrome: evidence from a meta-analysis of placebo-controlled randomized trials
    Patrick Haentjens
    Center for Outcomes Research and Laboratory for Experimental Surgery, Endocrinology, Pharmacology, and General Internal Medicine, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium
    Arch Intern Med 167:757-64. 2007
    b>Continuous positive airway pressure (CPAP) in patients with obstructive sleep apnea syndrome (OSAS) might lower blood pressure, but evidence from clinical studies is inconsistent, perhaps as a result of small sample size or heterogeneity ..
  8. ncbi Nasal CPAP or intubation at birth for very preterm infants
    Colin J Morley
    Neonatal Services, Royal Women s Hospital, Melbourne, Australia
    N Engl J Med 358:700-8. 2008
    ..This randomized trial investigated whether nasal continuous positive airway pressure (CPAP), rather than intubation and ventilation, shortly after birth would reduce the rate of death ..
  9. ncbi Obstructive sleep apnea: brain structural changes and neurocognitive function before and after treatment
    Nicola Canessa
    Center for Cognitive Neuroscience, Vita Salute San Raffaele University, Milan, Italy
    Am J Respir Crit Care Med 183:1419-26. 2011
    ..Knowledge of the brain structures involved in OSA and the corresponding functional implications could provide clues to the pathogenesis of cognitive impairment and its reversibility in this disorder...
  10. ncbi Cardiovascular mortality in women with obstructive sleep apnea with or without continuous positive airway pressure treatment: a cohort study
    Francisco Campos-Rodriguez
    Valme University Hospital, Seville, Spain
    Ann Intern Med 156:115-22. 2012
    ..Obstructive sleep apnea (OSA) is a risk factor for cardiovascular death in men, but whether it is also a risk factor in women is unknown...
  11. ncbi Noninvasive ventilation with continuous positive airway pressure acutely improves 6-minute walk distance in chronic heart failure
    Sérgio Chermont
    Post Graduate Program in Cardiovascular Sciences, Fluminense Federal University, Niteroi, Brazil
    J Cardiopulm Rehabil Prev 29:44-8. 2009
    Noninvasive ventilation with continuous positive airway pressure (CPAP) has been used in patients with chronic heart failure (CHF), although its effect on exercise tolerance in these patients is unknown...
  12. pmc A comparison of continuous and bi-level positive airway pressure non-invasive ventilation in patients with acute cardiogenic pulmonary oedema: a meta-analysis
    Kwok M Ho
    Department of Intensive Care, Royal Perth Hospital, Perth, Western Australia, Australia
    Crit Care 10:R49. 2006
    We conducted the present study to investigate the potential beneficial and adverse effects of continuous positive airway pressure (CPAP) compared with bi-level positive airway pressure (BiPAP) noninvasive ventilation in patients with ..
  13. pmc Inflammation, oxidative stress, and repair capacity of the vascular endothelium in obstructive sleep apnea
    Sanja Jelic
    Columbia University College of Physicians and Surgeons, Division of Pulmonary, Allergy, and Critical Care Medicine, PH8 Center, Room 840, 630 W 168th St, New York, NY 10032, USA
    Circulation 117:2270-8. 2008
    ..The effects of continuous positive airway pressure (CPAP) therapy on endothelial function and repair capacity were assessed.
  14. ncbi Fixed and autoadjusting continuous positive airway pressure treatments are not similar in reducing cardiovascular risk factors in patients with obstructive sleep apnea
    Vincenzo Patruno
    Department of Respiratory Rehabilitation, S Marta Hospital, Rivoli d Adda, Ospedale Maggiore, Crema, Italy
    Chest 131:1393-9. 2007
    ..b>Continuous positive airway pressure (CPAP) is the first-line therapy for OSA, able not only to reduce daytime sleepiness but also to ..
  15. ncbi Suppression of central sleep apnea by continuous positive airway pressure and transplant-free survival in heart failure: a post hoc analysis of the Canadian Continuous Positive Airway Pressure for Patients with Central Sleep Apnea and Heart Failure Trial
    Michael Arzt
    University of Toronto, Toronto, Ontario, Canada
    Circulation 115:3173-80. 2007
    In the main analysis of the Canadian Continuous Positive Airway Pressure (CPAP) for Patients with Central Sleep Apnea (CSA) and Heart Failure Trial (CANPAP), CPAP had no effect on heart transplant-free survival; however, CPAP only ..
  16. ncbi Sympathetic chemoreflex responses in obstructive sleep apnea and effects of continuous positive airway pressure therapy
    Virginia A Imadojemu
    Division of Pulmonary, Allergy and Critical Care, Penn State Heart and Vascular Institute, 500 University Drive, Hershey, PA 17033, USA
    Chest 131:1406-13. 2007
    ..Sympathetic nerve activity is increased in awake and regularly breathing patients with obstructive sleep apnea (OSA). Over time, repetitive hypoxic stress could alter sympathetic chemoreflex function in OSA...
  17. ncbi Spontaneous breathing patterns of very preterm infants treated with continuous positive airway pressure at birth
    Arjan B Te Pas
    Division of Newborn Services, Royal Women s Hospital, Carlton, Victoria 3053, Australia
    Pediatr Res 64:281-5. 2008
    ..convenience sample of spontaneously breathing infants <or=32 wk' gestation treated with facemask continuous positive airway pressure at birth. Airway pressure and flow were measured and each breath analyzed...
  18. ncbi Effects of exercise training associated with continuous positive airway pressure treatment in patients with obstructive sleep apnea syndrome
    Carolina Ackel-D'Elia
    Disciplina de Medicina e Biologia do Sono, Departamento de Psicobiologia, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brazil
    Sleep Breath 16:723-35. 2012
    The aim of this study was to evaluate the effects of a 2-month exercise training associated with continuous positive airway pressure (CPAP) treatment on the subjective and objective sleep measurements, quality of life, and mood in ..
  19. ncbi Practice parameters for the indications for polysomnography and related procedures: an update for 2005
    Clete A Kushida
    Stanford University Center of Excellence for Sleep Disorders, Stanford, CA, USA
    Sleep 28:499-521. 2005
    ..Polysomnography is routinely indicated for the diagnosis of sleep related breathing disorders; for continuous positive airway pressure (CPAP) titration in patients with sleep related breathing disorders; for the assessment of ..
  20. ncbi 8-Isoprostane, a marker of oxidative stress, is increased in exhaled breath condensate of patients with obstructive sleep apnea after night and is reduced by continuous positive airway pressure therapy
    Giovanna E Carpagnano
    Institute of Respiratory Diseases, University of Bari, Bari, Italy
    Chest 124:1386-92. 2003
    ..Obstructive sleep apnea (OSA) is characterized by recurrent apnea during sleep that may compromise oxidative balance. Oxidative stress is increased in the blood and in the airways of OSA patients...
  21. ncbi Executive function in patients with obstructive sleep apnea treated with continuous positive airway pressure
    Esther Yuet Ying Lau
    Department of Psychology, The University of Hong Kong, Hong Kong, China
    J Int Neuropsychol Soc 16:1077-88. 2010
    ..One important question is regarding the reversibility of cognitive deficits after treatment with continuous positive airway pressure (CPAP)...
  22. pmc Effects of nocturnal continuous positive airway pressure therapy in patients with resistant hypertension and obstructive sleep apnea
    Tarek A Dernaika
    University of Oklahoma Health Sciences Center, Pulmonary and Critical Care Medicine, 920 Stanton L Young Blvd, WP 1310, Oklahoma City, OK 73104, USA
    J Clin Sleep Med 5:103-7. 2009
    To examine the long-term effects of continuous positive airway pressure (CPAP) therapy on blood pressure (BP) in patients with obstructive sleep apnea and resistant hypertension.
  23. ncbi Evaluation of positive airway pressure treatment for sleep related breathing disorders in adults
    Peter Gay
    Mayo Clinic, Rochester, MN 55905, USA
    Sleep 29:381-401. 2006
    ..Finally, the use of bilevel PAP therapy is reviewed for both patients with OSA and those with other selected nocturnal breathing disorders. Each section also contains a brief summary and suggestions for future research...
  24. ncbi Effects of continuous positive airway pressure therapy withdrawal in patients with obstructive sleep apnea: a randomized controlled trial
    Malcolm Kohler
    Sleep Disorders Centre and Pulmonary Division, University Hospital Zurich, Zurich, Switzerland
    Am J Respir Crit Care Med 184:1192-9. 2011
    To establish a new approach to investigate the physiological effects of obstructive sleep apnea (OSA), and to evaluate novel treatments, during a period of continuous positive airway pressure (CPAP) withdrawal.
  25. ncbi Practice parameters for the treatment of snoring and Obstructive Sleep Apnea with oral appliances: an update for 2005
    Clete A Kushida
    Stanford University Center of Excellence for Sleep Disorders, CA, USA
    Sleep 29:240-3. 2006
    ..appliances (OAs) are indicated for use in patients with mild to moderate OSA who prefer them to continuous positive airway pressure (CPAP) therapy, or who do not respond to, are not appropriate candidates for, or who fail treatment ..
  26. ncbi Long-term effects of nasal continuous positive airway pressure therapy on cardiovascular outcomes in sleep apnea syndrome
    Liam S Doherty
    Respiratory Sleep Disorders Unit, St Vincent s University Hospital, Elm Park, Dublin 4, Ireland
    Chest 127:2076-84. 2005
    Obstructive sleep apnea syndrome (OSAS) has been associated with increased morbidity and mortality, principally from cardiovascular disease, but the impact of nasal continuous positive airway pressure (CPAP) therapy is unclear.
  27. ncbi Continuous positive airway pressure treatment rapidly improves insulin sensitivity in patients with obstructive sleep apnea syndrome
    Igor A Harsch
    Department of Medicine I, Friedrich Alexander University Erlangen Nuremberg, Erlangen, Germany
    Am J Respir Crit Care Med 169:156-62. 2004
    ..sleep apnea itself is an independent risk factor for increased insulin resistance and whether continuous positive airway pressure (CPAP) treatment improves insulin sensitivity...
  28. ncbi Continuous positive airway pressure treatment of mild to moderate obstructive sleep apnea reduces cardiovascular risk
    Nikolaus J Buchner
    Department of Internal Medicine I, Marienhospital Herne, Ruhr University Bochum, Hoelkeskampring 40, D 44625 Herne, Germany
    Am J Respir Crit Care Med 176:1274-80. 2007
    ..Obstructive sleep apnea (OSA) is linked to increased cardiovascular risk, but the impact of mild forms of OSA and their treatment on cardiovascular outcomes remains controversial...
  29. ncbi Continuous positive airway pressure treatment reduces mortality in patients with ischemic stroke and obstructive sleep apnea: a 5-year follow-up study
    Miguel Angel Martínez-García
    Unidad de Neumología, Hospital General de Requena, Paraje Casablanca s n 46340, Valencia, Spain
    Am J Respir Crit Care Med 180:36-41. 2009
    Obstructive sleep apnea (OSA) is an independent risk factor for stroke, but little is known about the role of continuous positive airway pressure (CPAP) on mortality in patients with stroke.
  30. ncbi Continuous positive airway pressure improves sleepiness but not calculated vascular risk in patients with minimally symptomatic obstructive sleep apnoea: the MOSAIC randomised controlled trial
    Sonya Elizabeth Craig
    Oxford Centre for Respiratory Medicine, Churchill Hospital, Oxford, UK
    Thorax 67:1090-6. 2012
    b>Continuous positive airway pressure (CPAP) for symptomatic obstructive sleep apnoea (OSA) improves sleepiness and reduces vascular risk, but such treatment for the more prevalent, minimally symptomatic disease is contentious.
  31. ncbi Continuous positive airway pressure for central sleep apnea and heart failure
    T Douglas Bradley
    Department of Medicine, University of Toronto, Toronto
    N Engl J Med 353:2025-33. 2005
    The Canadian Continuous Positive Airway Pressure for Patients with Central Sleep Apnea and Heart Failure trial tested the hypothesis that continuous positive airway pressure (CPAP) would improve the survival rate without heart ..
  32. ncbi Risk factors of the failure of surfactant treatment by transient intubation during nasal continuous positive airway pressure in preterm infants
    Ahmed Cherif
    Neonatal Intensive Care Unit, Neonatology and Maternity Center, Faculty of Medicine, Department of Neonatology, University of Tunis, Tunis, Tunisia
    Am J Perinatol 25:647-52. 2008
    ..associated with the failure of the INSURE method ( INtubation- SURfactant- Extubation) during nasal continuous positive airway pressure for preterm infants with respiratory distress syndrome...
  33. ncbi Lung and systemic inflammation in preterm lambs on continuous positive airway pressure or conventional ventilation
    Graeme R Polglase
    School of Women s and Infants Health, The University of Western Australia, Perth, Western Australia 6009, Australia
    Pediatr Res 65:67-71. 2009
    ..We aimed to determine in preterm lungs if continuous positive airway pressure (CPAP) protects against pulmonary and systemic inflammation, compared with conventional mechanical ..
  34. ncbi Influence of obstructive sleep apnea on mortality in patients with heart failure
    Hanqiao Wang
    Sleep Research Laboratory of the Toronto Rehabilitation Institute, Toronto, Ontario, Canada
    J Am Coll Cardiol 49:1625-31. 2007
    ..This study sought to determine, in patients with heart failure (HF), whether untreated moderate to severe obstructive sleep apnea (OSA) is associated with a higher mortality rate than in patients with mild to no sleep apnea (M-NSA)...
  35. ncbi Sleep-disordered breathing and continuous positive airway pressure compliance in a group of commercial bus drivers in Hong Kong
    David S C Hui
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong, China
    Respirology 11:723-30. 2006
    ..Sleep-disordered breathing may predispose drivers to road traffic accidents. However, CPAP acceptance and compliance among commercial bus drivers is unknown...
  36. pmc Randomised study of three non-surgical treatments in mild to moderate obstructive sleep apnoea
    Bing Lam
    Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China
    Thorax 62:354-9. 2007
    ..Patients with mild to moderate obstructive sleep apnoea (OSA) may be managed with different treatment options. This study compared the effectiveness of three commonly used non-surgical treatment modalities...
  37. ncbi Impact of continuous positive airway pressure therapy on blood pressure in patients with obstructive sleep apnea hypopnea: a meta-analysis of randomized controlled trials
    M Alajmi
    Department of Medicine, Respiratory Division, University of British Columbia, Vancouver, British Columbia, Canada
    Lung 185:67-72. 2007
    ..sleep apnea hypopnea (OSAH) are predisposed to developing hypertension, and therapy with continuous positive airway pressure (CPAP) may reduce blood pressure (BP)...
  38. ncbi Can psychological factors help us to determine adherence to CPAP? A prospective study
    M R Wild
    Section of Psychological Medicine, Academic Centre, Gartnavel Royal Hospital, 1055 Great Western Road, Glasgow, G12 0XH, UK
    Eur Respir J 24:461-5. 2004
    ..social cognitive variables may contribute to the explanation of variance in adherence to continuous positive airway pressure (CPAP) treatment for patients with obstructive sleep apnoea/hypopnoea syndrome (OSAHS)...
  39. ncbi Auto-titrating continuous positive airway pressure therapy in patients with chronic heart failure and obstructive sleep apnoea: a randomized placebo-controlled trial
    Lindsay A Smith
    Cardiovascular Research, Centre for Cardiovascular Science, University of Edinburgh, Chancellor s Building, 49 Little France Crescent, Edinburgh EH16 4SB, UK
    Eur Heart J 28:1221-7. 2007
    ..We aimed to determine whether treatment of OSA with continuous positive airway pressure (CPAP) would improve subjective and objective measures of heart failure severity in patients with ..
  40. ncbi Obstructive sleep apnea: effects of continuous positive airway pressure on cardiac remodeling as assessed by cardiac biomarkers, echocardiography, and cardiac MRI
    Jane Colish
    Department of Internal Medicine, St Boniface General Hospital, Winnipeg, Manitoba, Canada
    Chest 141:674-81. 2012
    ..demonstrated short-term improvement in cardiovascular remodeling in patients with OSA receiving continuous positive airway pressure (CPAP) therapy, a long-term study incorporating cardiac biomarkers, echocardiography, and cardiac ..
  41. ncbi The effects of continuous positive airway pressure therapy withdrawal on cardiac repolarization: data from a randomized controlled trial
    Valentina A Rossi
    Sleep Disorders Centre and Pulmonary Division, University Hospital of Zurich, Raemistrasse 100, Zurich, Switzerland
    Eur Heart J 33:2206-12. 2012
    ..The aim of the current trial was to assess the effects of continuous positive airway pressure (CPAP) therapy withdrawal on the measures of cardiac repolarization in patients with OSA.
  42. ncbi Long-term effect of continuous positive airway pressure in hypertensive patients with sleep apnea
    Ferran Barbe
    Coordinating Center, Institut de Recerca Biomèdica Lleida, Lleida, Spain
    Am J Respir Crit Care Med 181:718-26. 2010
    b>Continuous positive airway pressure (CPAP) is the current treatment for patients with symptomatic obstructive sleep apnea (OSA). Its use for all subjects with sleep-disordered breathing, regardless of daytime symptoms, is unclear.
  43. ncbi Low efficacy of atrial fibrillation ablation in severe obstructive sleep apnoea patients
    Maria Matiello
    Arrhythmia Section, Cardiology Department, Thorax Institute, Hospital Clinic Universitari, Institut de Investigació Biomèdica August Pi i Sunyer, University of Barcelona, 08036 Barcelona, Catalonia, Spain
    Europace 12:1084-9. 2010
    ..Although the association of obstructive sleep apnoea (OSA) and AF is well established, data on AF ablation efficacy in OSA are scarce. The aim of this study was to clarify the effect of OSA on the outcome of AF ablation...
  44. ncbi Continuous positive airway pressure therapy improves vascular dysfunction and decreases oxidative stress in patients with the metabolic syndrome and obstructive sleep apnea syndrome
    Jun ichi Oyama
    Department of Cardiovascular, Respiratory, and Geriatric Medicine, Kyushu University Hospital at Beppu and Medical Institute of Bioregulation, Kyushu University, Oita, Japan
    Clin Cardiol 35:231-6. 2012
    ..Therefore, nasal continuous positive airway pressure (CPAP) therapy may have beneficial effects in patients with the MetS and OSAS.
  45. ncbi Safety and efficacy of pulmonary vein antral isolation in patients with obstructive sleep apnea: the impact of continuous positive airway pressure
    Dimpi Patel
    St David s Medical Center, Austin, TX, USA
    Circ Arrhythm Electrophysiol 3:445-51. 2010
    Obstructive sleep apnea (OSA) may be associated with pulmonary vein antrum isolation (PVAI) failure. The aim of the present study was to investigate if treatment with continuous positive airway pressure (CPAP) improved PVAI success rates.
  46. ncbi Non-CPAP therapies in obstructive sleep apnoea: mandibular advancement device therapy
    Marie Marklund
    Dept of Orthodontics, Faculty of Medicine, Umea University, Umea, Sweden
    Eur Respir J 39:1241-7. 2012
    Mandibular advancement devices (MADs) represent the main non-continuous positive airway pressure (non-CPAP) therapy for patients with obstructive sleep apnoea (OSA)...
  47. ncbi Oxidative and carbonyl stress in patients with obstructive sleep apnea treated with continuous positive airway pressure
    Peter Celec
    Institute of Molecular Biomedicine, Comenius University, Sasinkova 4, 811 08, Bratislava, Slovakia
    Sleep Breath 16:393-8. 2012
    ..b>Continuous positive airway pressure (CPAP) improves symptoms and prognosis of patients with OSAS.
  48. pmc Updates on definition, consequences, and management of obstructive sleep apnea
    John G Park
    Division of Pulmonary and Critical Care Medicine, Center for Sleep Medicine, Mayo Clinic, Rochester, MN 55905, USA
    Mayo Clin Proc 86:549-54; quiz 554-5. 2011
    ..This review focuses on updates in the areas of terminology and testing, complications of untreated OSA, perioperative considerations, treatment options, and new developments in this field...
  49. ncbi Continuous positive airway pressure increases haemoglobin O2 saturation after acute but not prolonged altitude exposure
    Piergiuseppe Agostoni
    Centro Cardiologico Monzino, IRCCS, Istituto di Cardiologia, Universita di Milano, Via Parea 4, 20138 Milan, Italy
    Eur Heart J 31:457-63. 2010
    ..b>Continuous positive airway pressure (CPAP) removes extravascular lung fluids and improves haemoglobin oxygen saturation in acute ..
  50. ncbi Effect of nasal continuous positive airway pressure in uncontrolled nocturnal asthmatic patients with obstructive sleep apnea syndrome
    Tansu Ulukavak Ciftci
    Department of Pulmonary Disease, Faculty of Medicine, Gazi University, Ankara
    Respir Med 99:529-34. 2005
    ..were to evaluate the association of nocturnal asthma and OSAS, and investigate the influence of continuous positive airway pressure (CPAP) therapy to improve nighttime symptoms in asthmatic patients with OSAS...
  51. ncbi Continuous positive airway pressure and conventional mechanical ventilation in the treatment of meconium aspiration syndrome
    J P Goldsmith
    Department of Pediatrics, Tulane University, New Orleans, LA 70115 5034, USA
    J Perinatol 28:S49-55. 2008
    ..pathophysiology will help determine the appropriate treatment strategy, including the use of continuous positive airway pressure (CPAP), conventional mechanical ventilation (CMV) and other therapies...
  52. pmc Neighborhood of residence is associated with daily adherence to CPAP therapy
    Alec B Platt
    Center for Health Equity Research and Promotion, Philadelphia Veterans Affairs Medical Center Philadelphia, PA, USA
    Sleep 32:799-806. 2009
    Adherence to continuous positive airway pressure (CPAP) therapy for obstructive sleep apnea is poor. Risk factors for nonadherence are not well understood but may reflect individual or neighborhood socioeconomic factors...
  53. pmc Low socioeconomic status is a risk factor for CPAP acceptance among adult OSAS patients requiring treatment
    Tzahit Simon-Tuval
    Sleep Wake Disorders Unit, Soroka University Medical Center, Faculty of Health Sciences, Ben Gurion University of the Negev, Beer Sheva, Israel
    Sleep 32:545-52. 2009
    To evaluate whether socioeconomic status (SES) has a role in obstructive sleep apnea syndrome (OSAS) patients' decision to accept continuous positive airway pressure (CPAP) treatment.
  54. ncbi Effect of continuous positive airway pressure on ambulatory BP in patients with sleep apnea and hypertension: a placebo-controlled trial
    Francisco Campos-Rodriguez
    Department of Respiratory Medicine, University Hospital, 41020 Sevilla, Spain
    Chest 129:1459-67. 2006
    ..Several controlled trials have investigated the effect of continuous positive airway pressure (CPAP) on BP in patients with OSAS, but its effect on hypertensive patients has not been analyzed ..
  55. ncbi Continuous positive airway pressure treatment in sleep apnea patients with resistant hypertension: a randomized, controlled trial
    Lourdes Lozano
    Department of Pneumology, Hospital Mutua de Terrassa, Universitat Autonoma de Barcelona, Barcelona, Spain
    J Hypertens 28:2161-8. 2010
    This controlled trial assessed the effect of continuous positive airway pressure (CPAP) on blood pressure (BP) in patients with obstructive sleep apnea (OSA) and resistant hypertension (RH).
  56. ncbi Managing hypertension in obstructive sleep apnea: the interplay of continuous positive airway pressure, medication and chronotherapy
    Costas Tsioufis
    First Cardiology Clinic, University of Athens, Hippokration Hospital, Greece
    J Hypertens 28:875-82. 2010
    ..despite multiple interventions, namely lifestyle modifications, use of antihypertensive drugs and continuous positive airway pressure application...
  57. ncbi Continuous positive airway pressure treatment in patients with sleep apnoea: does it really improve glucose metabolism?
    Paschalis Steiropoulos
    Department of Pneumonology, Democritus University of Thrace, Alexandroupolis, Greece
    Curr Diabetes Rev 6:156-66. 2010
    ..Additionally, OSAS has been proposed as an independent risk factor for type 2 diabetes mellitus. Continuous Positive Airway Pressure (CPAP) is the treatment of choice for OSAS, since it eliminates upper airway collapse during sleep ..
  58. ncbi Delivery room continuous positive airway pressure/positive end-expiratory pressure in extremely low birth weight infants: a feasibility trial
    Neil N Finer
    Department of Pediatrics, University of California, 200 W Arbor Dr, 8774, San Diego, CA 92103 8774, USA
    Pediatrics 114:651-7. 2004
    ....
  59. ncbi Efficacy of positive airway pressure and oral appliance in mild to moderate obstructive sleep apnea
    Maree Barnes
    Institute for Breathing and Sleep, Austin Health, Melbourne, Victoria, Australia
    Am J Respir Crit Care Med 170:656-64. 2004
    ..participated in a randomized controlled crossover trial of 3 months of treatment with each of nasal continuous positive airway pressure (CPAP), a mandibular advancement splint, and a placebo tablet...
  60. ncbi Variables associated with the early failure of nasal CPAP in very low birth weight infants
    Amer Ammari
    Division of Neonatology Department of Pediatrics, College of Physicians and Surgeons, Columbia University, New York, New York 10032 3702, USA
    J Pediatr 147:341-7. 2005
    To identify risk factors and neonatal outcomes associated with the early failure of "bubble" nasal continuous positive airway pressure (CPAP) in very low birth weight (VLBW) infants with respiratory distress syndrome (RDS).
  61. ncbi Very early surfactant without mandatory ventilation in premature infants treated with early continuous positive airway pressure: a randomized, controlled trial
    Mario Augusto Rojas
    Vanderbilt University, Division of Neonatal Perinatal Medicine, Department of Pediatrics, Nashville, TN 37232 2370, USA
    Pediatrics 123:137-42. 2009
    ..ventilation is a major risk factor for chronic lung disease, the early application of nasal continuous positive airway pressure has been used as a strategy for avoiding mechanical ventilation in premature infants...
  62. ncbi Type 2 diabetes, glycemic control, and continuous positive airway pressure in obstructive sleep apnea
    Ambika R Babu
    Department of Medicine, Rush University Medical Center, Chicago, IL 60612, USA
    Arch Intern Med 165:447-52. 2005
    ..It has been previously shown that the severity of insulin resistance is related to the severity of SDB...
  63. ncbi Antioxidant status in patients with sleep apnoea and impact of continuous positive airway pressure treatment
    A Barcelo
    Serveis de Analisis Cliniques, and Pneumologia, Hospital Universitario Arnau de Vilanova, Lleida, Spain
    Eur Respir J 27:756-60. 2006
    ..Of these, 27 patients who used continuous positive airway pressure (CPAP) for >4 h.night-1 were re-examined 12 months later. Patients with OSAS had lower TAS (1...
  64. ncbi Effects of continuous positive airway pressure on early signs of atherosclerosis in obstructive sleep apnea
    Luciano F Drager
    Hypertension Unit, Heart Institute InCor, University of Sao Paulo Medical School, Sao Paulo, Brazil
    Am J Respir Crit Care Med 176:706-12. 2007
    ..Atherosclerosis is a key mechanism for these cardiovascular events. Recent cross-sectional studies showed the presence of early signs of atherosclerosis in patients with OSA who were free of comorbidities...
  65. ncbi Subjective fatigue and subjective sleepiness: two independent consequences of sleep disorders?
    Jamil L Hossain
    Sleep Research Unit and Department of Psychiatry, University of Toronto, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada
    J Sleep Res 14:245-53. 2005
    ..Furthermore, predominantly fatigued individuals with sleep disorders seem vulnerable to additional negative consequences due to possible interplay between amplified fatigue and psychological distress...
  66. ncbi Long-term effect of continuous positive airway pressure on BP in patients with hypertension and sleep apnea
    Francisco Campos-Rodriguez
    Departments of Respiratory Medicine, Valme University Hospital 41020 Sevilla, Spain
    Chest 132:1847-52. 2007
    To analyze the long-term effect of continuous positive airway pressure (CPAP) on ambulatory BP in patients with obstructive sleep apnea (OSA) and hypertension, and to identify subgroups of patients for whom CPAP could be more effective.
  67. ncbi A self-management approach to improving continuous positive airway pressure adherence and outcomes
    Carl J Stepnowsky
    Health Services Research and Development Unit, Veterans Affairs San Diego Healthcare System and Department of Psychiatry, University of California, San Diego, USA
    Behav Sleep Med 5:131-46. 2007
    ..Low patient adherence to nasal continuous positive airway pressure (CPAP) limits the effectiveness of treatment...
  68. ncbi Predicting treatment adherence in obstructive sleep apnea using principles of behavior change
    Mark S Aloia
    Department of Psychiatry and Human Behavior Brown Medical School, Providence, RI, USA
    J Clin Sleep Med 1:346-53. 2005
    ..To determine the relative predictive utility of measures of behavior-change principles on treatment adherence in individuals with obstructive sleep apnea...
  69. pmc A systematic review of CPAP adherence across age groups: clinical and empiric insights for developing CPAP adherence interventions
    Amy M Sawyer
    University of Pennsylvania School of Nursing, Biobehavioral Health Sciences Division, USA
    Sleep Med Rev 15:343-56. 2011
    b>Continuous positive airway pressure (CPAP) is a highly efficacious treatment for obstructive sleep apnea (OSA) but adherence to the treatment limits its overall effectiveness across all age groups of patients...
  70. ncbi Hemodynamic changes during weaning from nasal continuous positive airway pressure
    Hesham Abdel-Hady
    Neonatal Care Unit, Mansoura University Children s Hospital, Egypt
    Pediatrics 122:e1086-90. 2008
    Nasal continuous positive airway pressure is frequently used to support preterm infants with respiratory distress syndrome...
  71. ncbi Myocardial infarction rate in acute pulmonary edema: noninvasive pressure support ventilation versus continuous positive airway pressure
    Andrea Bellone
    Emergency Department, Niguarda Ca Granda Hospital, P za Ospedale, Milano, Italy
    Crit Care Med 32:1860-5. 2004
    ..We investigated whether the use of NIPSV increases the incidence of acute myocardial infarction compared with continuous positive airway pressure (CPAP) in patients with acute pulmonary edema.
  72. ncbi Influence of continuous positive airway pressure on outcomes of rehabilitation in stroke patients with obstructive sleep apnea
    Clodagh M Ryan
    Toronto Rehabilitation Institute, University of Toronto, Ontario, Canada
    Stroke 42:1062-7. 2011
    ..We hypothesized that treatment of OSA by continuous positive airway pressure (CPAP) in stroke patients would enhance motor, functional, and neurocognitive recovery.
  73. ncbi Infertility and obstructive sleep apnea: the effect of continuous positive airway pressure therapy on serum prolactin levels
    Madalina Minciu Macrea
    Salem Veterans Affairs Medical Center, Salem, VA, USA
    Sleep Breath 14:253-7. 2010
    ..to be related to the hypoxic stress and subsequently to result in reversible changes with effective continuous positive airway pressure (CPAP) therapy...
  74. pmc Gender differences in obstructive sleep apnea and treatment response to continuous positive airway pressure
    Lichuan Ye
    Boston College School of Nursing, Chestnut Hill, MA, USA
    J Clin Sleep Med 5:512-8. 2009
    ..exist in clinical manifestations of obstructive sleep apnea (OSA) and whether women's responses to continuous positive airway pressure (CPAP) are similar to those of men are critical areas of exploration in sleep disordered breathing...
  75. ncbi Effect of heated humidification on compliance and quality of life in patients with sleep apnea using nasal continuous positive airway pressure
    M Jeffery Mador
    Division of Pulmonary, Critical Care and Sleep Medicine, Section 111S, State University of New York at Buffalo, Veterans Administration Medical Center, Veterans Affairs Western New York Healthcare System, Buffalo, NY 14215, USA
    Chest 128:2151-8. 2005
    To determine whether the addition of heated humidification at treatment initiation with nasal continuous positive airway pressure (CPAP) would lead to better CPAP compliance and improve quality of life and subjective sleepiness in ..
  76. ncbi Use of continuous positive airway pressure reduces airway reactivity in adults with asthma
    Michael Busk
    Division of Pulmonary, Allergy, Critical Care, Occupational, and Sleep Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
    Eur Respir J 41:317-22. 2013
    ..modulator of airway responsiveness and we have previously demonstrated in animal models that continuous positive airway pressure (CPAP) resulted in lower in vivo airway reactivity...
  77. ncbi Predictors of compliance with continuous positive airway pressure treatment in patients with obstructive sleep apnea and metabolic syndrome
    Zuzana Sopkova
    Department of Respiratory Medicine and Tuberculosis, Faculty of Medicine, P J Safarik University and L Pasteur Teaching Hospital, Kosice, Slovakia
    Wien Klin Wochenschr 121:398-404. 2009
    b>Continuous positive airway pressure (CPAP) applied via a tight-fitting mask is the most effective treatment for obstructive sleep apnea (OSA) and has potential to improve the cardiovascular prognosis in such patients...
  78. ncbi Effects of continuous positive airway pressure on pulmonary function and exercise tolerance in patients with congestive heart failure
    Veronica L Wittmer
    Physiological Sciences Graduate Program, Biomedical Center, Federal University of Espirito Santo, Av Marechal Campos 1468, Vitoria, 29042 755 ES, Brazil
    Chest 130:157-63. 2006
    b>Continuous positive airway pressure (CPAP) has been used to improve cardiopulmonary function and reduce pulmonary edema symptoms in patients with congestive heart failure (CHF)...
  79. ncbi Bubble CPAP - a primary respiratory support for respiratory distress syndrome in newborns
    Prashanth S Urs
    M S Ramaiah Medical College and Teaching Hospital, Bangalore, India
    Indian Pediatr 46:409-11. 2009
    In preterm infants with respiratory distress syndrome (RDS), the application of continuous positive airway pressure (CPAP) is associated with benefits in terms of reduced respiratory failure and reduced mortality...
  80. pmc Canadian Thoracic Society guidelines: diagnosis and treatment of sleep disordered breathing in adults
    John Fleetham
    Respiratory Medicine, Diamond Health Care Centre, Vancouver, British Columbia V5Z 1M9
    Can Respir J 13:387-92. 2006
  81. ncbi The effects of nasal continuous positive airway pressure on platelet activation in obstructive sleep apnea syndrome
    David S Hui
    Department of Medicine and Therapeutics, Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Chest 125:1768-75. 2004
    A case-controlled study to assess the effects of nasal continuous positive airway pressure (CPAP) on platelet activation in patients with obstructive sleep apnea (OSAS) syndrome.
  82. ncbi Optimal level of nasal continuous positive airway pressure in severe viral bronchiolitis
    Sandrine Essouri
    AP HP, Pediatric Intensive Care Unit, Kremlin Bicetre Hospital, 78 rue du General Leclerc, 94270, Le Kremlin Bicetre, France
    Intensive Care Med 37:2002-7. 2011
    To determine the optimal level of nasal continuous positive airway pressure (nCPAP) in infants with severe hypercapnic viral bronchiolitis as assessed by the maximal unloading of the respiratory muscles and improvement of breathing ..
  83. ncbi Continuous positive airway pressure reduces postprandial lipidemia in obstructive sleep apnea: a randomized, placebo-controlled crossover trial
    Craig L Phillips
    Sleep and Circadian Research Group, Woolcock Institute of Medical Research, Sydney, New South Wales, Australia
    Am J Respir Crit Care Med 184:355-61. 2011
    ..Dyslipidemia is common in Obstructive Sleep Apnea (OSA). Postprandial lipidemia (PPL) is a strong marker of cardiovascular risk. Evidence that OSA treatment improves PPL is lacking...
  84. pmc Boussignac continuous positive airway pressure for the management of acute cardiogenic pulmonary edema: prospective study with a retrospective control group
    Willem Dieperink
    Thoraxcenter, Department of Cardiology, University Medical Center Groningen, University of Groningen, Hanzeplein 1 P O Box 30, 001, 9700 RB Groningen, The Netherlands
    BMC Cardiovasc Disord 7:40. 2007
    b>Continuous positive airway pressure (CPAP) treatment for acute cardiogenic pulmonary edema can have important benefits in acute cardiac care...
  85. ncbi Effects of nasal mask leak and heated humidification on nasal mucosa in the therapy with nasal continuous positive airway pressure (nCPAP)
    Yvonne Fischer
    Department of Otorhinolaryngology, Laboratory for Sleep Research and Sleep Medicine, University of Ulm, Frauensteige 12, 89075 Ulm, Germany
    Sleep Breath 12:353-7. 2008
    The purpose of this study was to determine the objective short-term influence of nasal continuous positive airway pressure (nCPAP) therapy, nasal mask leak (NML) and heated humidifiers (HH) to nasal conditioning of spontaneously ..
  86. ncbi Cerebral outcomes in a preterm baboon model of early versus delayed nasal continuous positive airway pressure
    Michelle Loeliger
    Department of Anatomy and Cell Biology, University of Melbourne, 3010, Victoria, Australia
    Pediatrics 118:1640-53. 2006
    ..of this work was to evaluate the influence of randomized respiratory therapy with either early continuous positive airway pressure or delayed continuous positive airway pressure preceded by positive pressure ventilation on the ..
  87. ncbi Recovery of heart rate variability in patients with moderate to severe obstructive sleep apnea after 6-month continuous positive airway pressure treatment
    Pimporn Limphanudom
    Division of Respiratory Disease and Tuberculosis, Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    J Med Assoc Thai 90:1530-5. 2007
    To evaluate the effect of long-term treatment with continuous positive airway pressure (CPAP) on the heart rate variability (HRV) of obstructive sleep apnea (OSA) patients.
  88. ncbi Early extubation and nasal continuous positive airway pressure after surfactant treatment for respiratory distress syndrome among preterm infants <30 weeks' gestation
    Carlo Dani
    Department of Surgical and Medical Critical Care, Division of Neonatology, Careggi University Hospital of Florence, Florence, Italy
    Pediatrics 113:e560-3. 2004
    ..that preterm infants with infant respiratory distress syndrome who are treated with nasal continuous positive airway pressure (NCPAP) and surfactant administration followed by immediate extubation and NCPAP application (SURF-..
  89. ncbi Continuous positive airway pressure as treatment for systemic hypertension in people with obstructive sleep apnoea: randomised controlled trial
    Joaquín Durán-Cantolla
    Sleep Unit, Hospital Universitario Txagorritxu, Facultad de Medicina, Universidad del Pais Vasco, Vitoria 01009, Spain
    BMJ 341:c5991. 2010
    To assess the effect of continuous positive airway pressure (CPAP) on 24 hour ambulatory blood pressure monitoring values in a large number of patients with untreated systemic hypertension of new onset and obstructive sleep apnoea.
  90. ncbi Cardiometabolic changes after continuous positive airway pressure for obstructive sleep apnoea: a randomised sham-controlled study
    Camilla M Hoyos
    Endocrine and Cardiometabolic Research Group, Woolcock Institute of Medical Research, University of Sydney, Glebe, Australia
    Thorax 67:1081-9. 2012
    ..The reversibility of these observed changes with continuous positive airway pressure (CPAP) treatment in men with OSA has not been systematically studied in a randomised sham-..
  91. ncbi Auto-adjusting versus fixed positive pressure therapy in mild to moderate obstructive sleep apnoea
    Geraldine M Nolan
    Respiratory Sleep Disorders Unit, St Vincent s University Hospital, Dublin, Ireland
    Sleep 30:189-94. 2007
    ..To determine if auto-adjusting positive airway pressure (APAP) would be better tolerated on the basis of delivering a lower mean pressure in patients with mild to moderate obstructive sleep apnoea syndrome (OSAS)...
  92. pmc Working memory in obstructive sleep apnea: construct validity and treatment effects
    Joshua C Felver-Gant
    Department of Psychiatry and Human Behavior, Brown Medical School, Providence, RI, USA
    J Clin Sleep Med 3:589-94. 2007
    ....
  93. ncbi Microvascular endothelial dysfunction in obstructive sleep apnea is caused by oxidative stress and improved by continuous positive airway pressure therapy
    Nikolaus J Buchner
    Department of Internal Medicine I, Marienhospital Herne, Ruhr University Bochum, Herne, Germany
    Respiration 82:409-17. 2011
    ..Endothelial dysfunction has recently been demonstrated in obstructive sleep apnea (OSA), but the underlying mechanisms are not entirely understood. Oxidative stress is a typical feature of OSA...
  94. ncbi Clinical and polysomnographic predictors of short-term continuous positive airway pressure compliance
    Jacob Collen
    Department of Internal Medicine, Walter Reed Army Medical Center, Washington, DC, USA
    Chest 135:704-9. 2009
    Poor compliance and initial intolerance limit the effectiveness of continuous positive airway pressure (CPAP) in obstructive sleep apnea. Short-term compliance has been shown to predict long-term use...
  95. ncbi Cardiovascular mortality in obstructive sleep apnea in the elderly: role of long-term continuous positive airway pressure treatment: a prospective observational study
    Miguel Angel Martínez-García
    Pneumology Service, La Fe University and Polytechnic Hospital, Bulevar Sur S N, Valencia, Spain
    Am J Respir Crit Care Med 186:909-16. 2012
    ..Obstructive sleep apnea (OSA) is a risk factor for cardiovascular death in middle-aged subjects, but it is not known whether it is also a risk factor in the elderly...
  96. ncbi Use of heated humidification during nasal CPAP titration in obstructive sleep apnoea syndrome
    M Duong
    Adelaide Instiute for Sleep Health, South Australia, Australia, and McMaster University, Health Science Centre, Room 3U24, Cardiorespiratory Research Unit, 1200 Main Street West, Hamilton, Ontario L8N 3Z5, Canada
    Eur Respir J 26:679-85. 2005
    Nasal symptoms associated with the use of nasal continuous positive airway pressure (nCPAP) in obstructive sleep apnoea (OSA) can adversely impact on patients' tolerance, acceptance and adherence to nCPAP therapy...
  97. ncbi Effects of 8 weeks of continuous positive airway pressure on abdominal adiposity in obstructive sleep apnoea
    Sheila Sivam
    Sleep and Circadian Research Group, Woolcock Institute of Medical Research, PO Box M77, Missenden Road, NSW 2050, Australia
    Eur Respir J 40:913-8. 2012
    The aim of the present study was to investigate the effect of continuous positive airway pressure (CPAP) treatment on regional adipose tissue distribution in patients with moderate or severe obstructive sleep apnoea...
  98. pmc Nasal CPAP reduces systemic blood pressure in patients with obstructive sleep apnoea and mild sleepiness
    D S Hui
    Department of Medicine and Therapeutics, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Thorax 61:1083-90. 2006
    A randomised controlled study was undertaken to examine the effect of nasal continuous positive airway pressure (CPAP) on 24 hour systemic blood pressure (BP) in patients with obstructive sleep apnoea (OSA).
  99. ncbi Quality of life, compliance, sleep and nasopharyngeal side effects during CPAP therapy with and without controlled heated humidification
    Karl Heinz Ruhle
    Department of Pneumology, University Witten Herdecke, Hagen, Germany
    Sleep Breath 15:479-85. 2011
    ..humidifier (cHH) on the quality of life (QOL), compliance and nasopharyngeal side effects during continuous positive airway pressure (CPAP) therapy in patients with obstructive sleep apnea syndrome (OSAS) in comparison with ..
  100. ncbi Effect of CPAP on QT interval dispersion in obstructive sleep apnea patients without hypertension
    Dursun Dursunoglu
    Pamukkale University Medical Faculty, Department of Cardiology, 20200 Kinikli, Denizli, Turkey
    Sleep Med 8:478-83. 2007
    ..We aimed to determine the effect of nasal continuous positive airway pressure (CPAP) therapy on QTcd in OSA patients without hypertension.
  101. pmc Acute and chronic effects of continuous positive airway pressure therapy on left ventricular systolic and diastolic function in patients with obstructive sleep apnea and congestive heart failure
    Chris B Johnson
    Department of Medicine, University of Ottawa, Ottawa, Canada
    Can J Cardiol 24:697-704. 2008
    Obstructive sleep apnea (OSA) may contribute to the pathogenesis of congestive heart failure (CHF). Nocturnal continuous positive airway pressure (CPAP) therapy can alleviate OSA and may have a role in the treatment of CHF patients.

Research Grants66

  1. Effective treatment of sleep apnea in prediabetes to reduce cardiometabolic risk
    Esra Tasali; Fiscal Year: 2010
    ..evidence to support a strong association between OSA and diabetes, it remains unclear today whether continuous positive airway pressure (CPAP) treatment of OSA can significantly improve glucose control...
  2. ECG-derived cardiopulmonary coupling biomarkers of sleep, sleep-breathing, and ca
    Robert J Thomas; Fiscal Year: 2010
    ..contribute to obstructive sleep apnea severity, be associated with induction of central apneas when continuous positive airway pressure (CPAP) is used for treatment, and possibly impair long term efficacy and tolerance...
  3. Oxygen versus PAP for treatment of sleep apnea in chronic heart failure
    Henry Klar Yaggi; Fiscal Year: 2013
    ..show improvement in left ventricular ejection fraction (LVEF) following treatment of CSA with continuous positive airway pressure (CPAP) or adaptive pressure-support servo-ventilation (ASV), although the single long-term outcome ..
  4. Randomized Trial of Antenatal Late Preterm Steroids (ALPS) - Clinical Coordinatin
    Ronald Wapner; Fiscal Year: 2012
    ..Respiratory support is defined as the use of continuous positive airway pressure or humidified high-flow nasal cannula for at least two continuous hours, oxygen requirement of FiO2 ..
  5. A randomized trial of bariatric surgery for the treatment of sleep apnea
    Sanjay R Patel; Fiscal Year: 2013
    ..The current first line treatment for moderate to severe OSA, nasal continuous positive airway pressure (CPAP) is extremely effective but is often not well tolerated, leading to low adherence rates in ..
  6. Sleep Disordered Breathing and Passive Limb Movement in Children with Paraplegia
    Marlyn Woo; Fiscal Year: 2013
    ..The most common intervention, continuous positive airway pressure, poses special problems with children and young adolescents, since the necessary masks distort ..
  7. Perioperative Use and Outcomes of Noninvasive Ventilation in Sleep Apnea
    Peter K Lindenauer; Fiscal Year: 2013
    ..The long-term treatment of OSA in the ambulatory setting consists of continuous positive airway pressure, a form of noninvasive ventilation (NIV)...
  8. Mechanisms of diaphragm muscle dysfunction in critical-illness myopathy
    CATHERINE S SASSOON; Fiscal Year: 2012
    ..of CMV-NMBA (cisatracurium);CMV-NMBA-MP3 (3 mg/kg/d), CMV-NMBA-MP30 (30 mg/kg/d) or 0 cm H2O of continuous positive airway pressure (CPAP [control])...
  9. Intermittent hypoxia, adiponectin, and insulin resistance in cardiovascular risk
    NARASIMHAM LAXMI PARINANDI; Fiscal Year: 2013
    ..Treatment of OSA with continuous positive airway pressure (CPAP) alleviates the IH during sleep, increases insulin sensitivity, as well as improves cardiac ..
  10. An RCT of telemedicine interventions for OSA
    DAVID W SPARROW; Fiscal Year: 2013
    ..The most common treatment is continuous positive airway pressure (CPAP), although adherence to CPAP is poor in more than one-third of patients...
  11. Prediction of Physiological Events in People with Sleep Disordered Breathing
    Jonathan A Waxman; Fiscal Year: 2011
    ..The most common therapy is continuous positive airway pressure (CPAP), which is difficult for many patients to tolerate...
  12. Obstructive Sleep Apnea in WTC Responders: Role of Nasal Pathology
    Jag Sunderram; Fiscal Year: 2013
    ..with significant morbidity and impact on quality of life that can be improved by treatment with continuous positive airway pressure (CPAP)...
  13. Reversibility of Cardiovascular Injury with CPAP Use: Mechanisms Involved
    Claudia E Korcarz; Fiscal Year: 2013
    ..Treatment with continuous positive airway pressure (CPAP) may reduce CVD risk;however, the mechanisms, time course, and durability of its benefit are ..
  14. A randomized cross over trial of two treatments for OSA in Veterans with PTSD
    ALI ALBERT EL SOLH; Fiscal Year: 2013
    ..Treatment of the underlying obstructive sleep disturbances with continuous positive airway pressure (CPAP) has resulted in restoration of sleep architecture, decrease daytime sleepiness, and ..
  15. Mechanisms of Altered Glucose Metabolism in Sleep-Disordered Breathing
    Naresh Punjabi; Fiscal Year: 2013
    ..We will also determine whether metabolic dysfunction in SDB is reversible with continuous positive airway pressure (CPAP) treatment. Specifically, we propose: 1...
  16. Intermittent Hypoxia: A Model to Study Circulatory Control in Humans
    Urs A Leuenberger; Fiscal Year: 2012
    ..reflex responses to hypoxia are enhanced in patients with sleep apnea and are normalized in part by continuous positive airway pressure therapy...
  17. Targeted Therapies for Selected Phenotypes of Obstructive Sleep Apnea
    Jerome A Dempsey; Fiscal Year: 2010
    ..About 15-30% of obstructive sleep apnea (OSA) patients have a poor tolerance for nasally-applied continuous positive airway pressure (CPAP) or develop problematic central apneas in response to this standard care...
  18. Reactive Oxygen Species in Intermittent Hypoxia induced Sympathoexcitation
    PETER BERNARD RAVEN; Fiscal Year: 2012
    ..Faculty has identified two subgroups of OSA patients using an innovative clinical index of continuous positive airway pressure (CPAP) treatment success...
  19. Vascular Endothelial Activation in Sleep Apnea
    Sanja Jelic; Fiscal Year: 2013
    ..OSA remains frequently unrecognized and a majority of OSA patients do not adhere to standard continuous positive airway pressure therapy...
  20. The Effect of Treatment of OSA on Diabetes Self Management and Glycemic Control
    Eileen R Chasens; Fiscal Year: 2013
    ..The most effective treatment for OSA, continuous positive airway pressure (CPAP), results in improved self-reported daytime functioning...
  21. Enhancing Motivation for CPAP Adherence in Obstructive Sleep Apnea
    Faith S Luyster; Fiscal Year: 2013
    ..b>Continuous positive airway pressure (CPAP) therapy is an effective treatment for obstructive sleep apnea (OSA), but adherence is poor...
  22. Promoting Adherence to Sleep Apnea Treatment among Blacks with Metabolic Syndrome
    Girardin Jean-Louis; Fiscal Year: 2012
    ..physician recommended sleep apnea assessment at 6 months and 2) greater adherence to treatment with Continuous Positive Airway Pressure post diagnosis;3) effects of the intervention on adherence rates will be sustained 6 months after ..
  23. Understanding the sleep apnea/insomnia interaction: a CPAP/sham-CPAP trial
    Nalaka S Gooneratne; Fiscal Year: 2013
    ..Accordingly, the investigators propose a controlled clinical intervention trial using a continuous positive airway pressure+contact control (CPAP+CC) arm, a sham-CPAP+CC arm and a CPAP+cognitive behavioral therapy for ..
  24. COGNITIVE BENEFITS OF TREATING SLEEP APNEA IN DEMENTIA
    Sonia Ancoli-Israel; Fiscal Year: 2011
    ..The state-of-the-art treatment for SDB is Continuous Positive Airway Pressure (CPAP)...
  25. Sleep Disordered Breathing in normal elderly and risk for Alzheimers Disease
    Ricardo S Osorio; Fiscal Year: 2013
    ..2) if these SDB related phenomena in normal elderly are susceptible to intervention with nasal continuous positive airway pressure (CPAP) in moderate-to-severe SDB subjects...
  26. The Role of Obstructive Sleep Apnea in the Acutely Decompensated Heart Failure
    Rami Khayat; Fiscal Year: 2009
    ..There is strong evidence that treatment of OSA with Continuous Positive Airway pressure (CPAP) reduces fatal and non-fatal cardiovascular events...
  27. Mechanical Airway Support Device to Treat Obstructive Sleep Disordered Breathing
    Philip M Wong; Fiscal Year: 2013
    ..b>Continuous positive airway pressure (CPAP) is currently an effective but expensive treatment, and the need for an electric outlet also ..
  28. Sleep apnea, Type 2 diabetes, and CVD: a cluster related to insulin resistance
    Gerald M Reaven; Fiscal Year: 2013
    ..experimental approaches will be used to evaluate the clinical and/or metabolic benefits of adding continuous positive airway pressure (CPAP) to PlO-treated and placebo-treated patients with OSA...
  29. Prospective Multicenter Study of Bronchiolitis Admissions: Etiology & Disposition
    Carlos A Camargo; Fiscal Year: 2010
    ..and low-risk clinical rules to predict reliably those children with bronchiolitis who would require continuous positive airway pressure or intubation and those who would not require intensive care...
  30. Sleep and Metabolism in Obesity: Impact of Gender
    David A Ehrmann; Fiscal Year: 2011
    ..obese men without OSA, b. obese men with OSA before and after treatment with continuous positive airway pressure (CPAP), c. obese pre-menopausal women without OSA, and d...
  31. Effect of Positive Airway Pressure on Reducing Airway Reactivity in Patients wit*
    Robert A Wise; Fiscal Year: 2013
    ..One such proposed treatment is continuous positive airway pressure (CPAP) which prevents the fall in end expiratory lung volume and prevents closure of airways in ..
  32. Sleep-Disordered Breathing and CPAP after Adenotonsillectomy in Children
    Ronald D Chervin; Fiscal Year: 2013
    ..that would merit further treatment remain poorly defined, and the potential clinical benefit of continuous positive airway pressure (CPAP), the mainstay of treatment for adult SDB, has not been well documented in children who have ..
  33. Inflammatory response to sleep apnea in obese subjects
    JULIO ALONSO CHIRINOS MEDINA; Fiscal Year: 2010
    ..of patients with obesity and moderate-severe OSA, and that therefore the elimination of apnea by continuous positive airway pressure (CPAP) therapy in these patients will more greatly reduce inflammation (measured by C-reactive ..
  34. OSA, Sleepiness, and Activity in Diabetes Management
    Eileen R Chasens; Fiscal Year: 2010
    ..We will examine if treatment of obstructive sleep apnea with continuous positive airway pressure results in increased physical activity in persons with type 2 diabetes.
  35. Mild Cognitive Impairment and Obstructive Sleep Apnea
    Kathy Culpepper Richards; Fiscal Year: 2013
    ..OSA is effectively treated with continuous positive airway pressure (CPAP), a pressurized nasal mask worn during sleep, but there is little information on its efficacy ..
  36. Fibromyalgia and Sleep Treatments
    Nancy A Hamilton; Fiscal Year: 2010
    ..g., fatigue, increased pain, etc.). Since treatment of SDB with continuous positive airway pressure (CPAP) can improve the above symptoms, treatment of SDB in FM patients might improve FM ..
  37. Obstructive Sleep Apnea Increases Cardiovascular Risk in Type 2 Diabetes
    Aristidis Veves; Fiscal Year: 2013
    ..second aim involves a prospective, randomized clinical trial which will examine the effect of nasal continuous positive airway pressure (CPAP) treatment on the cardiovascular risk...
  38. Effect of sleep apnea on nocturnal GnRH/LH secretion in children in early puberty
    NATALIE DARA SHAW; Fiscal Year: 2011
    ..To investigate this hypothesis, we will enroll 15 children in early puberty with OSA treated with a continuous positive airway pressure (CPAP) machine...
  39. A method for measuring and modeling the physiologic traits causing sleep apnea
    DAVID ANDREW WELLMAN; Fiscal Year: 2013
    ..for measuring and modeling the traits causing OSA (Aim 1), and then determine how effective non-continuous positive airway pressure therapies are at manipulating the traits (Aim 2)...
  40. Role of Sleep in Cognitive Declines in Normal Aging and Mild Cognitive Impairment
    MICHAEL SCULLIN; Fiscal Year: 2013
    ..Or, if sleep-disordered breathing events cause memory consolidation/pruning declines then continuous positive airway pressure (CPAP) treatment might be appropriate...
  41. Modulation of Airway Reactivity by Chronic Mechanical Strain
    Robert S Tepper; Fiscal Year: 2012
    ..Our laboratory has recently demonstrated that chronic mechanical strain produced by imposing continuous positive airway pressure (CPAP) on rabbit lungs in vivo for 4-5 days results in a dramatic reduction in airway responses to ..
  42. Multidisciplinary Treatment for Obstructive Sleep Apnea and Insomnia
    Jason C Ong; Fiscal Year: 2013
    ..that combines cognitive-behavior therapy (CBT) for insomnia delivered by a psychologist with Continuous Positive Airway Pressure (CPAP) therapy managed by a physician...
  43. Spousal Involvement in Adherence to CPAP Treatment
    Lichuan Ye; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Poor adherence to continuous positive airway pressure (CPAP) treatment remains the single largest impediment to effective management for obstructive sleep apnea (OSA)...
  44. Effects of Treating Obstructive Sleep Apnea in Epilepsy
    Beth Malow; Fiscal Year: 2004
    ..longitudinally through PSG confirmation and treatment of OSA and randomized to either therapeutic continuous positive airway pressure (CPAP) or sub-therapeutic (placebo or sham) CPAP in order to determine tolerability...
  45. MEASURING QOL DURING TREATMENT FOR SLEEP APNEA
    JEANNETTE BREUGELMANS; Fiscal Year: 2000
    ..a battery of quality of life instruments at baseline and 1-month after initiation of treatment with continuous positive airway pressure (CPAP)...
  46. CARDIORESPIRATORY TRANSFER IN OBSTRUCTIVE SLEEP APNEA
    MICHAEL KHOO; Fiscal Year: 2000
    ..The second major objective is to assess the long-term effects of continuous positive airway pressure (CPAP) therapy on cardiorespiratory transfer in OSAS and to elucidate the mechanisms that may ..
  47. Enabling Sleep Apnea Patient-Centered Care Via an Internet Intervention
    Carl Stepnowsky; Fiscal Year: 2009
    ..patient-centered, collaborative management for patients prescribed the gold-standard treatment, continuous positive airway pressure (CPAP). Poor treatment adherence with CPAP therapy is well-documented...
  48. Stretch and Vitamin A Effects on Alveolar Formation
    KURT ALBERTINE; Fiscal Year: 2009
    ..lambs (vitA+CV) permits alveolar formation that resembles the lungs of preterm lambs treated with continuous positive airway pressure (CPAP;preterm control), and term newborn lambs (gestation control)...
  49. ETHANOL AND RESPIRATORY DRIVE DURING SLEEP
    Merrill Mitler; Fiscal Year: 1991
    ..that in males who habitually snore, E increases upper airway resistance (measured by the nasal continuous positive airway pressure required to eliminate snoring) and can cause sleep apnea...
  50. Screening for Obstructive Sleep Apnea in Commercial Drivers
    Indira Gurubhagavatula; Fiscal Year: 2009
    ..A safe and effective therapy for sleep apnea is available in the form of continuous positive airway pressure, a pneumatic splint that prevents airway collapse during sleep...
  51. THE ROLE OF CYTOKINES IN SLEEPINESS AND SLEEP APNEA
    Alexandros Vgontzas; Fiscal Year: 2009
    ..e., continuous positive airway pressure (CPAP). Additionally, neutralizing TNFa in obese apneics reduces EDS markedly and significantly...
  52. CPAP--NEW THERAPY FOR HYPERNASAL SPEECH
    David Kuehn; Fiscal Year: 1993
    ..The proposed therapy involves an approach that has been used to treat sleep apnea patients, continuous positive airway pressure (CPAP)...
  53. Intelligent Quantitative CPAP for OSA therapy
    HANI KAYYALI; Fiscal Year: 2007
    ..DESCRIPTION (provided by applicant): The long term objective is to develop a new class of Continuous Positive Airway Pressure (CPAP) devices that in addition to treating OSA patients can conduct simultaneous cardiorespiratory ..
  54. Intelligent Quantitative CPAP for OSA therapy
    FREDERICK BUSCH; Fiscal Year: 2004
    The long term objective is to develop a new class of Continuous Positive Airway Pressure (CPAP) devices that in addition to treating OSA patients can simultaneously record EKG, pulse oximetry, respiration and airflow for accurate ..
  55. HEMODYNAMIC EVENTS IN SLEEP APNEA--CAUSES & CONSEQUENCES
    J Weiss; Fiscal Year: 1999
    ..However, recent investigations of OSA patients sleeping without obstructions on nasal continuous positive airway pressure suggest that the hemodynamic response to arousal is superimposed on an already abnormally elevated ..
  56. Upper Airway Motor Control during Sleep in Children
    Eliot Katz; Fiscal Year: 2007
    ..responses to hypercapnea (chemoresponsiveness); 3) Muscle and airway mechanical responses to continuous positive airway pressure (CPAP) and pulses of negative airway luminal pressure (mechanoresponsiveness); 4) Muscle and airway ..
  57. SHOCK IN INFANCY: METABOLIC AND HEMODYNAMIC ASPECTS
    MARC ROWE; Fiscal Year: 1980
    ..A second project soon to be completed indicates that in the injured lung high levels of continuous positive airway pressure are effective in increasing arterial oxygen tension but that transcutaneous oxygen does not rise ..
  58. APPLES: Apnea Positive Pressure Long-Term Efficacy Study
    Clete Kushida; Fiscal Year: 2007
    DESCRIPTION (provided by applicant): Nasal continuous positive airway pressure (CPAP) therapy is in widespread use as the primary treatment for the obstructive sleep apnea syndrome (OSAS), a sleep-related breathing disorder affecting ..
  59. NEUROCIRCULATORY RESPONSES IN OBSTRUCTIVE SLEEP APNEA
    VIRGINIA IMADOJEMU; Fiscal Year: 2003
    ..is to examine the effect of sympathetic blockade in OSA and to determine the effectiveness of nasal continuous positive airway pressure (nCPAP) therapy on sympathoexcitation...
  60. MULTISITE STUDY OF THE FUNCTIONAL OUTCOMES OF CPAP USE
    Terri Weaver; Fiscal Year: 1999
    ..to determine how obstructive sleep apnea syndrome (OSAS) is most effectively treated with nasal continuous positive airway pressure (CPAP) using Granger's (1984) model of functional assessment...
  61. Treatment of Obstructive Sleep Apnea After Stroke
    Devin L Brown; Fiscal Year: 2010
    ..is to assess the feasibility of performing a prospective, randomized, blinded, clinical trial of continuous positive airway pressure (CPAP) versus control (sham) CPAP in stroke patients, and to gain preliminary data on outcome ..
  62. PATIENT INTERFACE FOR CONTINUOUS POSITIVE AIRWAY PRESSUR
    HANI KAYYALI; Fiscal Year: 2001
    ..Nasal Continuous Positive Airway Pressure (N-CPAP) is the most effective OSA treatment; it opens the airways by creating positive pressure in ..
  63. Effects of Sleep Apnea Treatment on Metabolic Syndrome
    Susan Redline; Fiscal Year: 2006
    ..To test these hypotheses, we propose a rigorous controlled assessment of the effect of CPAP (continuous positive airway pressure) therapy on indices of metabolic syndrome, inflammation, and markers of endothelial function...
  64. Sympathetic and Vascular Function in Sleep Apnea
    URS LEUENBERGER; Fiscal Year: 2006
    ..demonstrated that OSA is accompanied by chronic sympathoexcitation that is in part reversible with continuous positive airway pressure (CPAP) therapy...
  65. Nocturnal hypoxemia and executive functions in OSA
    Brian Hoyt; Fiscal Year: 2003
    ..it has been inferred from the finding that these deficits do not improve following treatment with continuous positive airway pressure (CPAP)...